No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
805 |
4. Check minimum number of eventsNone |
805 |
5. Include endpointsNone |
805 |
6. Filter based on genotype QC (FinnGen only) |
789 |
Control definitions (FinnGen only)
- Control exclude
- G6_HYDROCEPH
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- G91
- Name in latin
- Hydrocephalia communicans
Similar endpoints
↥List of similar endpoints to
Communicating hydrocephalus
based on the number of shared cases.
Similar with more cases:
- Hydrocephalus
- Other neurological diseases
- Neurological diseases
- Neurological diseases, wide definition
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6750 | 3351 | 3305 |
| Only index persons | 4677 | 2460 | 2217 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.10 | 0.09 |
| Only index persons | 0.09 | 0.09 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 59.21 | 61.43 | 56.68 |
| Only index persons | 55.27 | 58.24 | 51.98 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 789 | 413 | 376 |
| Unadjusted period prevalence (%) | 0.16 | 0.15 | 0.17 |
| Median age at first event (years) | 60.89 | 59.89 | 61.98 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 805
- Matched controls
- 8050
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
+∞
314.9
281
*
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
8228.6
307.7
428
*
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
79.9
307.7
190
31
G91.0
ICD-10 Finland
Communicating hydrocephalus
+∞
307.7
734
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
22.4
292.3
237
147
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
42.6
243.9
150
43
AA1AA
NOMESCO Finland
Head X-ray examination
60.9
243.0
137
27
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
2745.3
237.6
218
*
AAF00
NOMESCO Finland
Ventriculostomy
458.8
212.8
204
6
AA1AD
NOMESCO Finland
CT of head and brain
8.0
192.6
522
1506
G91.1
ICD-10 Finland
Obstructive hydrocephalus
+∞
182.4
168
*
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
+∞
172.2
159
*
PA2CC
NOMESCO Finland
Cerebral very extensive angiography with X-ray
72.0
154.3
84
13
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
37.4
147.7
93
28
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
45.1
142.1
85
21
I60.2
ICD-10 Finland
Subarachnoid haemorrhage from anterior communicating artery
59.8
126.3
71
13
AAF15
NOMESCO Finland
Ventriculoatrial shunt
+∞
119.8
112
*
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
+∞
110.0
103
*
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
20.7
107.9
84
45
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
9.0
105.6
143
188
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
+∞
105.6
99
*
3313A
ICD-9 Finland
Other cerebral degenerations, Communicating hydrocephalus
+∞
100.1
94
*
I60.1
ICD-10 Finland
Subarachnoid haemorrhage from middle cerebral artery
41.6
95.3
58
15
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
21.0
94.8
73
38
N03AX14
ATC
levetiracetam; systemic
12.4
87.1
90
81
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
6.2
84.4
167
328
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
+∞
83.8
79
*
ZXD05
NOMESCO Finland
Urgent procedure
3.9
77.7
396
1616
AAF99
NOMESCO Finland
Other shunt operation on ventricle of brain or intracerebral cyst
763.6
72.3
70
*
XA800
NOMESCO Finland
Neuropsychological investigation
8.3
71.5
100
135
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
8.7
69.4
93
119
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
11.5
68.1
73
69
K90
ICPC
Stroke/cerebrovascular accident
9.0
67.0
87
107
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
11.9
62.2
65
59
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.9
59.8
152
367
AAA20
NOMESCO Finland
Insertion of intraventricular pressure monitoring device
621.9
59.5
58
*
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
11.3
59.3
64
61
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
10.8
57.3
64
64
G91.8
ICD-10 Finland
Other hydrocephalus
+∞
57.0
54
*
2132
FHL
Ventricular operators sunt
575.7
55.3
54
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
7.7
54.7
81
116
I60.7
ICD-10 Finland
Subarachnoid haemorrhage from intracranial artery, unspecified
200.3
54.7
56
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.6
54.2
230
803
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.5
53.7
242
878
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.4
53.2
262
1004
K91
ICPC
Cerebrovascular disease
13.2
52.5
51
41
I62.0
ICD-10 Finland
Nontraumatic subdural haemorrhage
21.5
51.6
39
19
R51.80
ICD-10 Finland
Headache
3.7
50.9
203
678
N03AG01
ATC
valproic acid; systemic, rectal
5.2
47.9
106
226
N03AB02
ATC
phenytoin; systemic
11.8
47.0
49
44
N18
ICPC
Paralysis/weakness
9.4
44.1
54
61
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
8.7
43.7
57
70
AAL00
NOMESCO Finland
Endovascular occlusion of intracranial aneurysm
+∞
42.0
40
*
N28
ICPC
Limited function/disability (N)
11.6
41.9
44
40
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
14.2
41.0
38
28
PA2LT
NOMESCO Finland
Endovascular closure of extensive brain aneurysm
79.5
40.3
45
6
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.2
39.9
119
321
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
7.6
39.0
57
80
ZXD35
NOMESCO Finland
Usual procedure
6.5
38.9
66
109
N03AF02
ATC
oxcarbazepine; oral
6.8
38.6
63
100
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
8.4
38.3
51
64
ZXE10
NOMESCO Finland
More than one and less than three hours
2.6
38.1
379
2053
Z2445
NOMESCO Finland
Psychologist
5.9
38.0
71
129
I60.0
ICD-10 Finland
Subarachnoid haemorrhage from carotid siphon and bifurcation
52.8
38.0
45
9
N29
ICPC
Neurological sympt/complt other
9.3
33.6
41
46
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
13.3
33.3
32
25
L28
ICPC
Limited function/disability (L)
2.8
32.2
213
931
TAB00
NOMESCO Finland
Lumbar puncture
4.7
31.8
78
180
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.2
31.7
144
511
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
10.4
31.1
35
35
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.6
29.5
105
319
G91.3
ICD-10 Finland
Post-traumatic hydrocephalus, unspecified
+∞
29.3
28
*
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
8.1
27.9
38
49
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
8.5
27.6
36
44
R56.8
ICD-10 Finland
Other and unspecified convulsions
4.2
27.4
76
193
N99
ICPC
Neurological disease other
11.1
27.0
29
27
SPAT1229
SPAT
Assessment of need for aid
3.4
26.9
106
343
2133
FHL
Suntin revisio
280.0
26.9
27
*
PA2MT
NOMESCO Finland
Endovascular closure of very extensive brain aneurysm
280.0
26.9
27
*
A28
ICPC
Limited function/disability NOS
2.5
26.8
207
967
R42
ICD-10 Finland
Dizziness and giddiness
2.4
26.5
242
1221
N03AF01
ATC
carbamazepine; oral, rectal
4.0
26.2
80
218
3314A
ICD-9 Finland
Other cerebral degenerations, Obstructive hydrocephalus
+∞
26.2
25
*
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.0
25.7
127
470
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.4
25.5
99
317
Z98.2
ICD-10 Finland
Presence of cerebrospinal fluid drainage device
+∞
25.1
24
*
AAF50
NOMESCO Finland
Third ventriculostomy
+∞
25.1
24
*
I60.6
ICD-10 Finland
Subarachnoid haemorrhage from other intracranial arteries
72.3
24.9
28
*
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
4.5
24.9
64
153
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
5.6
24.8
48
90
SPAT1216
SPAT
Assessment of functional ability
2.5
24.1
179
817
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.2
23.9
322
1894
XCK00
NOMESCO Finland
Perimetry
3.5
23.8
87
268
H53.4
ICD-10 Finland
Visual field defects
6.1
23.7
42
72
H47.2
ICD-10 Finland
Optic atrophy
34.6
23.5
30
9
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
31.1
22.9
30
10
M03BX01
ATC
baclofen; systemic
6.4
22.1
37
60
-, ,
ICD-10 Finland
5.3
21.9
45
89
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
39.9
21.8
27
7
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
8.0
21.8
30
39
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
3.0
21.3
101
364
I60.3
ICD-10 Finland
Subarachnoid haemorrhage from posterior communicating artery
51.5
21.2
25
5
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.2
21.2
92
315
R4120
NOMESCO Finland
Occupational therapy
3.4
21.0
81
258
PA2KT
NOMESCO Finland
Endovascular closure of brain aneurysm
38.3
20.9
26
7
ZXA00
NOMESCO Finland
Right side
2.1
20.4
270
1558
SPAT1234
SPAT
Support of social functional capacity
3.6
20.3
70
207
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
3.2
20.0
83
276
G91
ICD-10 Finland
Hydrocephalus
+∞
19.9
19
*
A06AD11
ATC
lactulose; oral
2.3
19.7
176
866
N06AB04
ATC
citalopram; systemic
2.2
19.4
203
1067
2161
FHL
Neck ligation, big brain
32.2
19.3
25
8
4300A
ICD-9 Finland
Subarachnoid haemorrhage[HAEMORRHAGIA SUBARACHNOID. POST ANEURYSMA SACCULARE]
26.8
19.2
26
10
P20
ICPC
Memory disturbance
2.4
18.9
155
734
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
8.3
18.8
25
31
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.2
18.5
77
257
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
18.4
241
1376
R1250
NOMESCO Finland
Evaluation of functional capability
5.3
18.3
37
72
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.7
18.1
105
421
R4150
NOMESCO Finland
Neuropsychological rehabilitation
17.0
18.0
28
17
AA1BD
NOMESCO Finland
Extensive CT of head and brain
5.2
17.8
37
74
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
17.7
342
2230
Y83.1
ICD-10 Finland
Surgical operation with implant of artificial internal device as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
6.5
17.7
29
46
GBB00
NOMESCO Finland
Tracheostomy
7.7
17.0
24
32
T90.5
ICD-10 Finland
Sequelae of intracranial injury
7.7
17.0
24
32
PA2AC
NOMESCO Finland
Cerebral angiography with X-ray
16.7
16.6
26
16
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
4.9
16.5
37
79
N05BA09
ATC
clobazam; oral
15.8
16.3
26
17
R53
ICD-10 Finland
Malaise and fatigue
2.0
16.3
224
1295
F03
ICD-10 Finland
Unspecified dementia
3.2
16.1
67
223
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.2
16.0
156
790
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
3.6
16.0
55
162
S06.0
ICD-10 Finland
Concussion
2.4
15.8
114
508
2124
FHL
Intracranial pressure measurement, intraventricular
+∞
15.7
15
*
2130
FHL
Ventricular atrial shunt
+∞
15.7
15
*
183
Kela drug reimbursment
Lamotrigin and topiramate
12.0
15.6
28
24
I60.4
ICD-10 Finland
Subarachnoid haemorrhage from basilar artery
86.8
15.6
17
*
I60.8
ICD-10 Finland
Other subarachnoid haemorrhage
163.0
15.5
16
*
AAK00
NOMESCO Finland
Cranioplasty
163.0
15.5
16
*
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.6
15.4
97
405
G04BD07
ATC
tolterodine; oral
3.1
15.4
66
224
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.8
15.2
81
310
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
5.8
15.2
28
50
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.7
15.1
49
139
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
14.3
15.1
25
18
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.2
14.9
138
683
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
3.7
14.9
49
140
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.1
14.8
157
821
AAF10
NOMESCO Finland
Lumboperitoneal shunt
+∞
14.6
14
*
N05AH04
ATC
quetiapine; oral
2.1
14.5
155
813
R11
ICD-10 Finland
Nausea and vomiting
2.6
14.4
93
392
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
4.9
14.1
31
65
N03AX09
ATC
lamotrigine; oral
3.5
14.0
49
146
Z3229
NOMESCO Finland
Other healthcare associate professional
2.5
13.9
91
387
G41.9
ICD-10 Finland
Status epilepticus, unspecified
20.5
13.8
20
10
N05AX08
ATC
risperidone; systemic
2.4
13.7
98
434
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.4
13.6
103
468
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
142.3
13.5
14
*
G81.1
ICD-10 Finland
Spastic hemiplegia
142.3
13.5
14
*
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
142.3
13.5
14
*
AAK80
NOMESCO Finland
Partial excision of skull cap
142.3
13.5
14
*
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
11.7
13.4
24
21
R41.0
ICD-10 Finland
Disorientation, unspecified
3.6
13.1
44
128
AAD05
NOMESCO Finland
Evacuation of acute subdural haematoma
17.1
13.0
20
12
G44.2
ICD-10 Finland
Tension-type headache
2.2
12.8
120
596
2139
FHL
Other measure in this category
+∞
12.5
12
*
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
12.2
131
686
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
9.8
11.8
23
24
WYA20
NOMESCO Finland
Home visit
4.5
11.8
29
67
A04
ICPC
Weakness/tiredness general
2.0
11.7
133
710
PA2YT
NOMESCO Finland
Cerebral artery PTA with stent
30.5
11.7
15
5
Q03.9
ICD-10 Finland
Congenital hydrocephalus, unspecified
+∞
11.5
11
*
N05BA01
ATC
diazepam; systemic, rectal
2.1
11.4
122
636
N03AX18
ATC
lacosamide; systemic
12.0
11.4
20
17
G40.10
ICD-10 Finland
Simple partial seizures
12.0
11.4
20
17
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.1
11.2
46
152
F06.7
ICD-10 Finland
Mild cognitive disorder
3.5
10.8
37
109
PA2BG
NOMESCO Finland
MRI examination of vessels in the head with high intensity magnet
18.1
10.8
16
9
N05CD08
ATC
midazolam; nasal, systemic
3.6
10.7
35
100
PA2AD
NOMESCO Finland
CT angiography of brain
13.1
10.7
18
14
SPAT1053
SPAT
Memory test
2.0
10.6
137
763
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
10.6
236
1556
W19
ICD-10 Finland
Unspecified fall
2.2
10.5
97
477
R51
ICD-10 Finland
Headache
3.0
10.5
48
169
S06.3
ICD-10 Finland
Focal brain injury
5.5
10.4
20
37
AAK85
NOMESCO Finland
Replantation of previously excised part of skull cap
+∞
10.4
10
*
2127
FHL
Ventriculostomy
+∞
10.4
10
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
10.4
156
913
ZXC86
NOMESCO Finland
Use of endoscopic device
16.3
10.4
16
10
G00.9
ICD-10 Finland
Bacterial meningitis, unspecified
33.0
10.4
13
*
G03.9
ICD-10 Finland
Meningitis, unspecified
23.7
10.3
14
6
N06AB10
ATC
escitalopram; oral
1.9
10.2
149
864
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.2
10.1
86
410
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
9.3
10.1
20
22
I60.5
ICD-10 Finland
Subarachnoid haemorrhage from vertebral artery
40.6
10.0
12
*
U04
ICPC
Incontinence urine
2.5
9.9
61
251
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.0
9.8
109
575
N05AH03
ATC
olanzapine; systemic
2.7
9.8
54
210
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
8.9
9.8
20
23
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
10.8
9.8
18
17
Z3231
NOMESCO Finland
Registered nurse
1.7
9.8
228
1517
AWE00
NOMESCO Finland
Reoperation for deep heamorrhage in surgery of the nervous system
55.7
9.7
11
*
R5110, ,
SPAT
2.5
9.7
64
273
I61.5
ICD-10 Finland
Intracerebral haemorrhage, intraventricular
101.2
9.4
10
*
4380A
ICD-9 Finland
Late effects of cerebrovascular disease[SEQUELAE MORBI CEREBROVASCULARIS]
17.8
9.4
14
8
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
+∞
9.4
9
*
GBB13
NOMESCO Finland
Revision of tracheostomy
+∞
9.4
9
*
TGB20
NOMESCO Finland
Tracheostomy tube replacement
+∞
9.4
9
*
GBB03
NOMESCO Finland
Percutaneous tracheostomy
+∞
9.4
9
*
G97.2
ICD-10 Finland
Intracranial hypotension following ventricular shunting
+∞
9.4
9
*
JDB10
NOMESCO Finland
Percutaneous gastrostomy
7.0
9.4
22
32
R32
ICD-10 Finland
Unspecified urinary incontinence
3.5
9.3
32
95
SPAT1231
SPAT
Assessment of adjustments needed in living environment
4.0
9.2
26
67
Z75.5
ICD-10 Finland
Holiday relief care
5.1
9.1
19
38
RS221, ,
NOMESCO Finland
4.7
9.1
21
46
I61.1
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, cortical
8.4
9.1
19
23
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
9.1
142
841
Z03
ICPC
Housing/neighbourhood problem
10.2
9.1
17
17
G41.0
ICD-10 Finland
Grand mal status epilepticus
37.1
9.0
11
*
Z43.0
ICD-10 Finland
Attention to tracheostomy
37.1
9.0
11
*
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
8.1
8.9
19
24
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
8.9
149
901
Z3226
NOMESCO Finland
Physiotherapist
1.8
8.9
155
949
G04BD09
ATC
trospium; oral
3.5
8.7
30
89
T85.7
ICD-10 Finland
Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
50.5
8.7
10
*
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
91.0
8.4
9
*
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
6.8
8.4
20
30
Z08
ICPC
Social welfare problem
5.0
8.4
18
37
SPAT1301
SPAT
No procedures
1.6
8.3
250
1763
7423A
ICD-9 Finland
Other congenital anomalies of nervous system, Congenital hydrocephalus
+∞
8.3
8
*
Q03.0
ICD-10 Finland
Malformations of aqueduct of Sylvius
+∞
8.3
8
*
G90.1
ICD-10 Finland
Familial dysautonomia [Riley-Day]
+∞
8.3
8
*
34793
ICD-8 Finland
Other disease of brain, Hydrocephalus acquisitus NUD
+∞
8.3
8
*
I60
ICD-10 Finland
Subarachnoid haemorrhage
+∞
8.3
8
*
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
2.5
8.3
52
216
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.0
8.3
88
457
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.0
8.2
36
124
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
4.0
8.2
23
59
SPAT1245
SPAT
Provision of support and information to patient’s family members
2.6
8.1
48
194
I69.2
ICD-10 Finland
Sequelae of other nontraumatic intracranial haemorrhage
17.4
8.1
12
7
AA5PD
NOMESCO Finland
CT examination of brain pefusion
6.4
8.0
20
32
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
0.5
8.0
67
1292
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.0
8.0
88
462
L29
ICPC
Musculoskeletal sympt/complt other
2.2
8.0
70
337
R55
ICD-10 Finland
Syncope and collapse
1.9
8.0
104
580
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
4.3
8.0
20
47
OAB43, ,
SPAT
0.4
8.0
36
885
N05AD01
ATC
haloperidol; systemic
3.1
8.0
33
110
A29
ICPC
General symptom/complaint other
1.9
8.0
111
633
XFP96
NOMESCO Finland
Other intraoperative electrophysiological investigation in arhythmia or disturbance of impulse propagation
3.7
7.9
25
70
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
6.2
7.9
20
33
G04BD08
ATC
solifenacin; oral
2.2
7.9
65
306
R4110
NOMESCO Finland
Physiotherapy
1.6
7.8
218
1507
G40
ICD-10 Finland
Epilepsy
6.5
7.7
19
30
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
3.9
7.7
22
57
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
15.2
7.7
12
8
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
4.4
7.7
19
44
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.6
7.7
44
175
SPAT1252
SPAT
Overall medication plan or its review
2.2
7.7
66
316
N30.0
ICD-10 Finland
Acute cystitis
1.8
7.6
126
757
R26.0
ICD-10 Finland
Ataxic gait
18.6
7.6
11
6
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
7.6
100
559
G40.89
ICD-10 Finland
Other epilepsy
12.0
7.6
13
11
D33.30
ICD-10 Finland
Acoustic neuroma
12.0
7.6
13
11
RL140, ,
NOMESCO Finland
25.3
7.6
10
*
H47.1
ICD-10 Finland
Papilloedema, unspecified
10.2
7.6
14
14
Z02.4
ICD-10 Finland
Examination for driving licence
0.5
7.4
86
1490
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
2.5
7.4
45
185
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
6.9
7.3
17
25
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
11.0
7.3
13
12
RP120, ,
NOMESCO Finland
+∞
7.3
7
*
G94.2
ICD-10 Finland
Hydrocephalus in other diseases classified elsewhere
+∞
7.3
7
*
74200
ICD-8 Finland
Congenital hydrocephalus, Communicans
+∞
7.3
7
*
74209
ICD-8 Finland
Congenital hydrocephalus, Unspecified
+∞
7.3
7
*
ZXA05
NOMESCO Finland
Left side
1.6
7.3
205
1419
AAA27
NOMESCO Finland
Insertion of intracerebral pressure monitoring device
30.3
7.2
9
*
G41.2
ICD-10 Finland
Complex partial status epilepticus
30.3
7.2
9
*
4309X
ICD-9 Finland
Subarachnoid haemorrhage[HAEMORRHAGIA SUBARACHNOIDALIS NUD]
30.3
7.2
9
*
AA9CW, ,
NOMESCO Finland
20.2
7.1
10
5
XX4AW, ,
NOMESCO Finland
20.2
7.1
10
5
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
12.2
7.1
12
10
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.3
7.1
54
246
G04BD12
ATC
mirabegron; oral
1.8
7.1
103
595
R1260
NOMESCO Finland
Evaluation of communicative skills
3.5
7.0
24
71
J01EA01
ATC
trimethoprim; systemic
1.6
7.0
209
1465
S06.6
ICD-10 Finland
Traumatic subarachnoid haemorrhage
5.9
6.9
18
31
Z43.5
ICD-10 Finland
Attention to cystostomy
7.6
6.9
15
20
P03
ICPC
Feeling depressed
2.1
6.9
62
302
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
13.9
6.9
11
8
RS313, ,
NOMESCO Finland
13.9
6.9
11
8
N02BE01
ATC
paracetamol; systemic, rectal
1.7
6.9
680
6134
L76
ICPC
Fracture: other
2.9
6.9
31
109
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.4
6.8
44
186
WX882
NOMESCO Finland
High dependency care
2.9
6.8
32
115
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
5.7
6.8
18
32
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
40.4
6.8
8
*
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
7.3
6.7
15
21
Z02.7
ICD-10 Finland
Issue of medical certificate
2.2
6.6
57
273
N05AB03
ATC
perphenazine; systemic, rectal
2.8
6.6
32
117
Z29
ICPC
Social problem NOS
3.4
6.6
23
69
G93.0
ICD-10 Finland
Cerebral cysts
12.4
6.6
11
9
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
4.2
6.6
17
41
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
3.9
6.6
19
50
N05BA04
ATC
oxazepam; oral
1.6
6.5
201
1415
Z2446
NOMESCO Finland
Social worker
2.1
6.5
61
303
N03AX11
ATC
topiramate; oral
3.5
6.5
22
65
XKC03
NOMESCO Finland
Water cystometry
2.8
6.4
31
113
R4130
NOMESCO Finland
Speech therapy
3.0
6.4
27
91
G00.3
ICD-10 Finland
Staphylococcal meningitis
70.4
6.4
7
*
N05AD03
ATC
melperone; systemic
3.6
6.3
20
56
H53.2
ICD-10 Finland
Diplopia
2.8
6.3
31
114
M01AH05
ATC
etoricoxib; oral
0.7
6.3
281
3558
N06AB03
ATC
fluoxetine; oral
1.8
6.3
96
562
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
11.1
6.3
11
10
TJD20
NOMESCO Finland
Change of gastrostomy tube
9.4
6.3
12
13
2152
FHL
Extraction, big brain
18.2
6.3
9
5
Q05.2
ICD-10 Finland
Lumbar spina bifida with hydrocephalus
+∞
6.3
6
*
SPAT1063
SPAT
Suctioning of mucus from airways
+∞
6.3
6
*
P52.2
ICD-10 Finland
Intraventricular (nontraumatic) haemorrhage, grade 3, and grade 4 of fetus and newborn
+∞
6.3
6
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.8
6.2
96
564
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
7.8
6.1
13
17
SPAT1042
SPAT
Guidance concerning balance maintenance
12.6
6.1
10
8
SPAT1240
SPAT
Therapeutic discussion
2.0
6.1
69
367
N06DA02
ATC
donepezil; oral
2.0
6.1
65
339
RT150, ,
NOMESCO Finland
10.1
6.0
11
11
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
5.6
6.0
16
29
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
155
52
36.68
240.89
4.5
1.2
—
—
—
0
0
197
131
19.59
232.73
3.8
1.6
35.28
6.65
e6/l
1.99
155
95
197
131
19.59
232.73
3.8
1.7
2275.85
1022.92
e6/l
0.50
155
98
104
24
49.61
177.32
4.4
1.1
—
—
—
0
0
117
134
10.05
95.97
2.9
1.6
3.56
3.76
mmol/l
0.88
112
125
47
40
12.42
46.68
2.3
1.5
—
—
—
0
0
189
785
2.84
31.46
9.7
8.1
1.58
1.29
mmol/l
0.57
148
630
34
36
9.82
29.02
1.2
1.0
460.18
557.05
ng/l
0.48
11
22
34
36
9.82
29.02
1.2
1.0
284.50
267.32
ng/l
0.07
12
22
34
36
9.82
29.02
1.2
1.0
33.65
37.75
ng/l
0.14
12
20
30
9
34.55
23.48
2.8
1.0
31.96
—
%
—
24
0
330
1978
2.13
23.16
2.9
2.1
228.14
286.84
u/l
0.45
309
1864
81
251
3.48
21.91
9.0
3.9
1.57
1.35
mmol/l
0.66
81
245
277
1610
2.10
20.57
4.8
4.1
90.53
88.57
%
0.70
267
1570
113
445
2.79
20.25
14.6
7.7
24.59
24.38
mmol/l
0.20
108
425
165
813
2.29
18.31
9.3
7.4
—
—
—
0
0
192
1046
2.10
16.41
2.4
2.2
28.65
29.68
s
1.40
184
1010
252
1554
1.90
14.94
2.6
2.4
—
—
—
0
0
233
1412
1.91
14.50
5.5
4.3
1.02
1.02
kg/l
0.22
17
209
121
592
2.23
13.41
2.8
2.4
5.19
6.41
ug/l
0.28
107
515
83
345
2.57
13.24
9.3
10.4
24.37
24.63
mmol/l
0.40
83
335
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
22
37
6.08
12.64
1.6
1.1
—
—
—
0
0
259
1688
1.79
12.46
5.5
4.2
0.00
0.00
estimate
0.50
47
555
336
2384
1.70
11.81
4.0
3.4
—
—
—
0
0
157
896
1.93
11.41
5.7
6.0
1.00
1.07
mmol/l
2.16
149
826
22
29
7.77
9.95
2.4
2.4
57.97
46.98
umol/l
0.56
17
24
396
3032
1.60
9.71
8.8
6.4
1.20
1.21
mmol/l
3.08
375
2758
21
29
7.41
9.26
2.1
1.1
—
—
—
0
0
166
1061
1.71
8.11
3.6
3.8
0.84
0.82
mmol/l
2.42
156
996
525
5996
0.64
7.79
3.9
4.5
1.41
1.46
mmol/l
1.71
487
5447
465
3806
1.53
7.77
9.0
5.2
6.89
6.73
mmol/l
0.83
453
3579
133
820
1.75
7.35
1.7
1.9
—
—
—
0
0
505
5791
0.66
7.30
3.8
4.1
1.37
1.28
mmol/l
1.99
472
5228
533
6038
0.65
7.17
4.0
4.6
4.50
4.59
mmol/l
1.21
496
5529
548
6172
0.65
7.16
4.7
5.1
2.62
2.69
mmol/l
0.94
512
5614
533
6034
0.65
7.09
4.3
4.7
6.02
6.00
mmol/l
0.10
504
5424
130
811
1.72
6.87
1.7
1.8
—
—
—
0
0
102
598
1.81
6.67
7.7
7.6
1.40
1.36
mmol/l
0.20
102
584
408
3321
1.46
6.53
9.2
7.1
1.20
1.21
mmol/l
2.63
372
2840
35
138
2.61
6.27
1.8
1.5
—
—
—
0
0
515
5804
0.69
5.84
17.8
14.4
83.23
78.09
ml/min/173m2
4.94
436
4778
164
1135
1.56
5.68
1.7
1.8
—
—
—
0
0
363
2943
1.43
5.66
3.0
2.7
—
—
—
0
0
16
35
4.64
5.19
1.9
1.1
—
—
—
0
0
376
3103
1.40
5.13
5.0
4.0
0.00
0.00
estimate
0.50
52
617
73
419
1.82
5.13
1.7
1.5
—
—
—
0
0
163
1163
1.50
4.86
3.4
2.9
1.82
1.24
e6/l
0.66
93
677
373
3103
1.38
4.72
6.0
5.4
0.00
0.00
estimate
-0.00
51
567
43
805
0.51
4.61
4.5
4.6
31.68
32.31
%
0.15
28
528
376
3144
1.37
4.56
5.0
4.0
0.00
0.01
estimate
0.50
50
553
346
2861
1.37
4.48
5.3
5.0
34.36
35.31
g/l
2.32
321
2664
41
203
2.07
4.45
1.3
1.2
—
—
—
0
0
33
150
2.25
4.43
1.7
3.4
26.94
34.58
umol/l
1.94
33
134
15
420
0.34
4.41
1.7
1.7
—
—
—
0
0
519
5750
0.73
4.38
5.5
6.0
39.64
40.26
mmol/mol
0.84
487
5285
482
5380
0.74
4.09
25.9
18.6
15.15
15.12
%
0.04
476
5279
8
10
8.07
4.06
1.5
1.0
—
—
—
0
0
172
1283
1.43
4.04
3.0
3.0
2.46
2.45
mmol/l
0.24
153
1132
234
1846
1.38
3.97
4.1
3.3
0.31
0.53
e6/l
1.64
187
1409
90
593
1.58
3.84
2.9
3.7
5.06
4.53
kpa
0.88
85
571
340
3962
0.75
3.74
3.1
3.2
50.08
51.17
u/l
0.12
317
3663
371
3162
1.32
3.71
12.8
16.1
1.18
1.28
inr
1.24
71
902
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
10
20
5.05
3.69
1.7
2.5
137.50
134.85
%
—
10
20
181
1395
1.38
3.49
3.0
2.7
5.72
5.44
e6/l
0.09
170
1258
291
2412
1.32
3.49
5.3
4.2
—
—
—
0
0
16
58
2.79
3.43
2.3
2.4
—
—
—
0
0
9
19
4.78
3.24
1.1
1.0
1681.22
1691.89
miu/ml
—
9
19
65
983
0.63
3.18
1.1
1.3
13.25
9.65
u/ml
0.22
22
355
64
408
1.62
3.15
1.7
1.6
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
40
224
1.83
3.12
5.7
2.9
0.34
0.35
u/ml
0.11
24
124
624
6631
0.74
3.12
11.0
10.7
25.40
25.56
u/l
0.09
606
6369
144
1090
1.39
3.08
4.3
3.1
2.43
2.14
e6/l
0.16
76
608
96
679
1.47
2.98
3.6
4.5
1.39
1.82
mmol/l
0.60
77
553
44
712
0.60
2.87
3.3
4.1
4.21
25.88
ug/l
1.27
37
602
268
2247
1.29
2.84
3.0
3.5
2.36
2.35
mmol/l
0.30
238
1975
72
1039
0.66
2.83
1.2
1.3
35.44
35.23
iu/ml
0.01
26
333
26
485
0.52
2.81
2.6
2.1
—
—
—
0
0
74
504
1.52
2.77
3.4
2.7
71.27
64.06
ml/min/173m2
0.63
30
210
299
2549
1.28
2.76
3.6
3.9
28.17
52.91
ng/l
1.15
226
1880
23
441
0.51
2.71
2.3
2.0
—
—
—
0
0
6
10
6.04
2.70
1.3
1.0
109.50
108.00
%
—
6
10
242
2014
1.29
2.70
4.5
3.4
47.80
98.74
e6/l
0.79
195
1556
27
141
1.95
2.63
1.3
1.4
—
—
—
0
0
5
8
6.28
2.37
1.0
1.3
—
—
—
0
0
8
22
3.66
2.37
1.0
1.1
—
—
—
0
0
14
59
2.40
2.30
1.1
1.1
—
—
—
0
0
6
14
4.31
2.15
1.3
1.2
—
—
—
0
0
168
2031
0.78
2.14
3.8
3.8
7.80
8.42
mg/mmol
0.08
116
1289
15
68
2.23
2.12
1.2
1.0
—
—
—
0
0
665
6932
0.77
2.11
30.8
22.6
131.98
134.40
g/l
3.79
651
6803
319
3587
0.82
2.09
2.5
2.8
—
—
—
0
0
17
82
2.10
2.08
1.1
1.3
—
—
—
0
0
665
6929
0.77
2.07
30.7
22.5
4.39
4.46
e12/l
3.40
648
6702
95
1234
0.74
2.06
2.4
3.1
0.62
0.77
ug/l
1.28
69
817
665
6926
0.77
2.03
30.6
22.5
256.98
246.20
e9/l
3.41
648
6724
665
6926
0.77
2.03
30.8
22.6
39.61
39.77
%
0.33
617
6427
10
231
0.43
2.02
1.3
1.6
—
126.67
—
0
9
160
1315
1.27
1.93
1.6
1.7
1375.63
1188.17
nmol/l
1.99
134
977
14
65
2.17
1.89
1.1
1.0
—
—
—
0
0
8
28
2.88
1.86
1.1
1.3
—
—
—
0
0
16
301
0.52
1.85
1.0
1.0
—
—
—
0
0
65
471
1.41
1.84
2.2
1.7
—
—
—
0
0
12
54
2.24
1.74
1.2
1.0
—
—
—
0
0
5
13
3.86
1.71
1.4
1.8
16.20
16.06
umol/l
—
5
13
11
48
2.31
1.71
1.4
1.5
—
—
—
0
0
73
958
0.74
1.70
1.4
1.5
—
—
—
0
0
79
600
1.35
1.70
2.4
2.0
458.84
376.21
nmol/l
0.44
74
549
11
50
2.22
1.57
1.4
1.2
1.23
1.51
nmol/l
0.44
11
44
42
291
1.47
1.54
2.7
2.0
3.76
2.56
ug/l
0.20
37
259
5
15
3.35
1.52
1.0
1.1
—
—
—
0
0
6
21
2.87
1.51
1.2
1.1
112.67
114.63
%
—
6
16
6
21
2.87
1.51
1.0
1.1
—
—
—
0
0
6
21
2.87
1.51
1.0
1.1
—
—
—
0
0
438
4694
0.85
1.45
3.6
4.2
14.83
13.13
mm/h
1.20
412
4290
165
1920
0.82
1.44
3.5
3.2
756.19
281.62
mg/l
0.44
116
1233
9
41
2.21
1.37
1.1
1.0
—
—
—
0
0
6
23
2.62
1.37
1.0
1.1
—
—
—
0
0
5
17
2.95
1.36
1.0
2.2
11.60
15.35
pmol/l
—
5
11
142
1658
0.83
1.28
2.7
2.9
342.31
8091.24
umol/l
7.38
118
1431
19
303
0.62
1.27
4.8
2.9
44.61
66.83
u/ml
0.47
19
288
179
2041
0.84
1.24
3.3
3.2
7.26
7.40
mmol/l
0.16
160
1701
239
2657
0.86
1.21
2.8
2.8
112.17
139.70
ug/l
1.80
222
2411
28
189
1.50
1.20
3.6
1.5
—
—
—
0
0
8
154
0.51
1.15
1.8
2.2
131.25
128.20
g/l
—
8
113
189
2131
0.85
1.14
4.1
5.2
2.85
2.84
ug/l
0.00
172
1888
547
5719
0.86
1.14
4.5
4.6
1.96
2.17
mu/l
0.47
512
5141
8
40
2.01
1.12
1.5
1.7
—
—
—
0
0
143
1647
0.84
1.11
1.6
1.7
1.49
1.36
mmol/l
0.99
127
1361
182
1604
1.17
1.11
1.5
1.5
21.13
20.62
nmol/l
0.15
169
1345
7
31
2.27
1.10
10.3
13.5
1734.00
1589.94
nmol/l
—
7
31
9
165
0.54
1.09
1.6
1.3
—
—
—
0
0
25
360
0.68
1.07
1.1
1.2
179.35
141.67
iu/ml
0.17
13
138
7
33
2.13
1.05
1.4
2.9
114.86
100.12
%
—
7
33
15
90
1.68
1.04
1.2
1.7
—
—
—
0
0
15
90
1.68
1.04
1.2
1.7
—
—
—
0
0
186
2085
0.86
1.04
2.5
3.1
1387.87
1608.90
ng/l
0.22
166
1793
28
197
1.44
1.01
3.4
3.3
92.07
90.20
%
0.15
28
189
7
135
0.51
0.99
1.1
1.3
—
—
—
0
0
5
23
2.18
0.98
1.0
1.0
—
—
—
0
0
33
241
1.39
0.98
2.0
2.2
361.13
474.67
ug/l
0.21
28
221
281
3043
0.88
0.94
5.7
5.9
57.72
57.31
%
0.22
265
2850
8
146
0.54
0.93
1.4
1.1
—
—
—
0
0
14
220
0.63
0.93
3.3
2.0
—
—
—
0
0
10
55
1.83
0.92
1.8
1.4
30.35
29.92
u/l
—
10
45
5
101
0.49
0.90
1.4
1.6
—
—
—
0
0
286
3084
0.89
0.88
5.9
6.1
27.51
27.54
%
0.01
271
2886
6
31
1.94
0.84
1.3
1.1
—
—
—
0
0
146
1294
1.16
0.84
3.8
4.0
371.48
299.49
ng/l
0.14
123
1054
21
146
1.45
0.83
1.3
1.3
—
—
—
0
0
21
146
1.45
0.83
1.3
1.3
—
—
—
0
0
33
249
1.34
0.83
1.4
2.8
9.95
10.43
g/l
0.38
25
223
6
115
0.52
0.83
3.0
3.4
4.92
4.41
e9/l
—
6
115
0
25
0.00
0.79
0.0
3.6
—
215.52
—
0
25
56
677
0.81
0.76
4.3
3.5
—
—
—
0
0
12
184
0.65
0.74
3.5
1.9
—
—
—
0
0
121
1364
0.87
0.74
1.2
1.3
0.74
1.75
u/ml
2.64
34
357
30
228
1.33
0.74
2.3
3.1
0.43
1.33
g/l
1.63
23
201
288
2691
1.11
0.72
2.1
2.0
93.59
94.37
pmol/l
0.12
154
1388
68
574
1.20
0.71
2.0
3.2
67.11
66.19
g/l
0.43
59
523
10
158
0.63
0.71
1.3
1.4
—
—
—
0
0
32
248
1.30
0.70
1.6
2.9
2.93
3.00
g/l
0.14
24
223
34
266
1.29
0.69
1.5
2.8
3.45
3.53
g/l
0.16
26
242
154
1393
1.13
0.68
1.4
1.7
464.76
10327004.91
pmol/l
0.80
132
1133
34
267
1.29
0.68
1.5
2.8
7.18
7.41
g/l
0.23
26
242
34
267
1.29
0.68
1.5
2.8
—
—
—
0
0
7
120
0.58
0.68
3.3
3.8
56.14
58.84
%
—
7
120
35
436
0.79
0.64
3.3
2.2
10.27
12.81
nmol/l
1.36
35
384
28
217
1.30
0.62
1.5
2.9
38.16
37.79
g/l
0.11
20
192
6
101
0.59
0.62
4.0
3.8
—
748.50
—
0
10
5
30
1.67
0.61
1.0
1.0
—
—
—
0
0
29
227
1.29
0.60
10.8
3.8
8.74
8.48
kpa
0.36
29
222
25
196
1.28
0.53
1.4
3.1
0.00
0.00
g/l
-0.00
20
179
9
132
0.68
0.52
1.4
1.2
—
—
—
0
0
9
65
1.39
0.50
1.6
1.3
568975.56
185535.86
e6/l
—
9
44
26
208
1.26
0.48
1.6
3.1
0.00
0.03
g/l
0.50
21
191
7
111
0.63
0.48
1.4
1.6
—
—
—
0
0
190
2030
0.92
0.48
2.4
2.6
54.76
100.97
u/l
0.61
179
1870
5
83
0.60
0.46
1.8
1.4
—
—
—
0
0
5
83
0.60
0.46
1.0
1.0
—
—
—
0
0
16
121
1.33
0.44
1.2
1.7
—
—
—
0
0
16
121
1.33
0.44
1.2
1.7
—
—
—
0
0
9
128
0.70
0.43
1.4
1.4
—
—
—
0
0
10
139
0.72
0.42
2.3
2.6
16.80
16.05
%
—
5
76
355
3416
1.07
0.42
5.4
6.4
10.64
12.22
umol/l
1.83
337
3233
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
66
738
0.88
0.40
3.1
4.4
231.15
264.32
u/l
0.85
55
699
7
102
0.68
0.39
2.9
1.4
—
—
—
0
0
11
81
1.36
0.36
1.2
1.5
—
—
—
0
0
11
146
0.75
0.36
1.4
1.3
—
—
—
0
0
6
45
1.34
0.34
1.3
1.5
—
275.00
—
0
6
384
3726
1.06
0.33
8.9
9.1
4.57
4.16
e9/l
2.09
332
3249
15
187
0.80
0.32
1.2
1.4
329.56
286.15
ug/g
—
9
103
15
186
0.80
0.31
4.7
6.1
1.57
1.49
mg/l
0.10
15
168
7
99
0.70
0.31
1.1
1.3
—
—
—
0
0
20
167
1.20
0.28
1.6
1.8
32732.07
14973.56
e6/l
0.40
14
124
54
594
0.90
0.27
2.4
3.2
186.62
239.15
ng/l
0.55
47
546
5
72
0.69
0.26
2.0
1.6
—
—
—
0
0
9
75
1.20
0.25
1.1
1.6
—
—
—
0
0
22
189
1.17
0.24
1.2
1.2
—
—
—
0
0
164
1712
0.95
0.23
2.2
2.1
3.03
3.10
mg/l
0.15
143
1440
59
544
1.09
0.23
4.2
3.8
85.54
84.55
ng/l
0.04
49
477
5
39
1.28
0.23
1.4
1.3
—
—
—
0
0
5
40
1.25
0.22
1.4
2.4
—
—
—
0
0
22
191
1.16
0.22
1.2
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
5
43
1.16
0.21
1.0
1.9
—
—
—
0
0
5
43
1.16
0.21
1.0
1.9
—
—
—
0
0
20
173
1.16
0.21
1.4
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
2.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
0.88
—
0
9
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
17
196
0.86
0.19
1.5
1.9
—
—
—
0
0
21
238
0.88
0.18
2.2
3.0
—
—
—
0
0
14
164
0.85
0.18
1.2
1.4
—
—
—
0
0
167
1727
0.96
0.17
4.1
4.4
21.69
21.26
%
0.14
77
829
32
291
1.10
0.17
1.3
2.0
1.47
1.54
g/l
0.16
25
259
32
292
1.10
0.16
1.3
1.3
—
—
—
0
0
26
235
1.11
0.16
1.8
1.6
—
—
—
0
0
19
168
1.13
0.16
1.4
1.2
—
—
—
0
0
13
150
0.86
0.14
2.1
1.7
33.92
40.77
nmol/l
0.75
13
143
56
593
0.94
0.14
2.2
2.4
36.58
113.51
u/l
0.46
43
495
267
2617
1.03
0.13
2.1
2.3
77.56
77.64
nmol/l
0.01
245
2314
8
98
0.81
0.13
1.0
1.1
—
—
—
0
0
9
106
0.85
0.13
1.2
1.7
—
—
—
0
0
20
219
0.91
0.11
1.4
1.2
0.30
1.73
u/ml
—
5
17
480
4754
1.02
0.11
3.7
3.8
14.96
14.90
pmol/l
0.18
441
4246
13
146
0.89
0.10
1.6
1.6
2.00
6.35
iu/l
—
5
39
136
1394
0.97
0.10
2.2
1.8
1.33
1.27
mg/l
0.13
108
1085
10
87
1.15
0.09
1.1
1.8
—
—
—
0
0
496
4920
1.02
0.09
6.7
7.6
81.90
80.58
u/l
0.25
474
4594
5
48
1.04
0.09
1.2
1.1
—
94.40
—
0
5
17
185
0.92
0.08
1.6
1.6
—
—
—
0
0
5
60
0.83
0.08
1.2
1.3
—
—
—
0
0
5
63
0.79
0.08
2.8
2.1
—
—
—
0
0
5
63
0.79
0.08
1.0
1.1
—
—
—
0
0
653
6502
1.02
0.07
26.0
18.1
139.40
139.64
mmol/l
1.20
642
6324
7
83
0.84
0.07
1.3
1.2
0.54
0.57
nmol/l
—
7
76
204
2011
1.02
0.07
3.2
3.3
37.13
32.47
u/l
0.26
191
1913
17
183
0.93
0.06
1.8
1.8
—
—
—
0
0
102
1042
0.98
0.06
2.8
2.5
12.43
12.61
umol/l
0.09
96
972
10
90
1.11
0.05
1.3
1.1
2.00
6.46
u/ml
—
5
37
38
366
1.04
0.05
4.7
3.0
0.34
0.26
e6/l
0.19
38
354
77
753
1.02
0.05
2.2
3.0
7.90
7.96
umol/l
0.01
63
655
12
130
0.92
0.04
1.3
1.7
—
—
—
0
0
624
6259
0.99
0.04
22.9
15.4
27.44
24.81
mg/l
1.11
535
4990
48
468
1.03
0.03
7.7
4.2
1.82
1.76
mmol/l
0.05
35
347
18
171
1.05
0.03
1.2
1.7
—
—
—
0
0
19
181
1.05
0.03
1.3
1.4
—
—
—
0
0
12
128
0.94
0.02
1.4
1.6
—
—
—
0
0
76
770
0.99
0.02
1.3
1.4
—
—
—
0
0
653
6521
1.01
0.01
25.0
18.3
3.96
3.99
mmol/l
2.15
642
6336
95
958
0.99
0.01
2.8
2.5
2.18
2.32
g/l
1.73
89
891
18
174
1.04
0.00
1.2
1.7
—
—
—
0
0
90
902
1.00
0.00
3.0
2.5
23.81
22.21
%
0.42
82
774
65
651
1.00
0.00
1.4
1.7
1.57
1.51
%
0.34
55
563
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
2.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
6
61
0.98
0.00
1.7
2.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
2.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
66.88
—
0
8
0
9
0.00
0.00
0.0
7.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
3.4
—
83.80
—
0
8
0
5
0.00
0.00
0.0
1.2
—
16.60
—
0
5
0
6
0.00
-0.00
0.0
2.5
—
0.83
—
0
6
8
82
0.98
-0.00
1.3
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
-0.00
6.5
2.9
60.83
54.77
%
—
6
55
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
11.41
—
0
7
0
6
0.00
-0.00
0.0
4.3
—
—
—
0
0
26
260
1.00
-0.00
1.8
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint G6_HCCOMM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_HCCOMM | 3.207 [2.83, 3.63] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.446 |
During the follow-up period (1.1.1998 — 31.12.2019), 862 out of 2207 females with G6_HCCOMM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_HCCOMM | 3.268 [2.82, 3.79] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.014 |
During the follow-up period (1.1.1998 — 31.12.2019), 835 out of 2089 males with G6_HCCOMM died.
Mortality risk
Mortality risk for people of age
years, who have G6_HCCOMM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.237% | 0.734% |
| 5 | 1.673% | 3.6% |
| 10 | 4.418% | 9.74% |
| 15 | 9.011% | 17.976% |
| 20 | 15.437% | 29.439% |
Relationships between endpoints
↥Index endpoint: G6_HCCOMM – Communicating hydrocephalus
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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