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Hypothyroidism, drug reimbursement

HYPOTHY_REIMB

hypothyroidism: Abnormally low levels of thyroid hormone.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

KELA reimbursements: KELA codes 104

1 out of 7 registries used, show all original rules.

13880

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Check minimum number of events None

13880

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Include endpoints None

13880

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Remove individuals based on genotype QC

13428

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HYPOTHY_REIMB

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 13428 11093 2335
Unadjusted prevalence (%) 3.26 4.82 1.28
Mean age at first event (years) 46.95 46.02 51.35

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.22 [1.00, 1.49] 5.1e-2 1439
15 years 0.01 0.89 [0.75, 1.04] 1.5e-1 573
5 years 0.00 0.97 [0.80, 1.18] 7.8e-1 160
1 year 0.00 1.43 [1.03, 1.99] 3.5e-2 41

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: HYPOTHY_REIMB – Hypothyroidism, drug reimbursement
GWS hits: 27

Survival analyses between endpoints

Plot

before Hypothyroidism, drug reimbursement
after Hypothyroidism, drug reimbursement

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypothyroidism, drug reimbursement

Endpoint not on priority list, no data to show.