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Hypothyroidism, drug reimbursement


hypothyroidism: Abnormally low levels of thyroid hormone.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

KELA reimbursements: KELA codes 104

1 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 13428 11093 2335
Unadjusted prevalence (%) 3.26 4.82 1.28
Mean age at first event (years) 46.95 46.02 51.35


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.22 [1.00, 1.49] 5.1e-2 1439
15 years 0.01 0.89 [0.75, 1.04] 1.5e-1 573
5 years 0.00 0.97 [0.80, 1.18] 7.8e-1 160
1 year 0.00 1.43 [1.03, 1.99] 3.5e-2 41

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: HYPOTHY_REIMB – Hypothyroidism, drug reimbursement
GWS hits: 27

Survival analyses between endpoints


before Hypothyroidism, drug reimbursement
after Hypothyroidism, drug reimbursement

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Drugs most likely to be purchased after Hypothyroidism, drug reimbursement

Endpoint not on priority list, no data to show.