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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Toxic colitis

COLITTOX

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K52.1
  • Cause of death: ICD-10 K52.1

2 out of 7 registries used, show all original rules.

111

4. Check minimum number of events

None

111

5. Include endpoints

None

111

6. Filter based on genotype QC (FinnGen only)

111

Control definitions (FinnGen only)

Control exclude
K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K52
Name in latin
Gastroenteritis toxica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 111 59 52
Unadjusted period prevalence (%) 0.02 0.02 0.02
Median age at first event (years) 55.78 47.20 65.51

-FinnGen-

Age distribution of first events

0103040506070809002468101214161820AgeIndividuals

-FinnGen-

Year distribution of first events

197019751980198519901995200020052010201520202023024681012141618202224YearIndividuals

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
103
Matched controls
1029
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K52.1
ICD-10 Finland
Toxic gastroenteritis and colitis
+∞
148.5
103
*
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
21.6
20
*
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
130.4
20.4
21
*
A07EC02
ATC
mesalazine; oral, rectal
58.5
20.2
23
5
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
+∞
14.9
14
*
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
+∞
14.9
14
*
K51.5
ICD-10 Finland
Left sided colitis
+∞
13.9
13
*
130
Kela drug reimbursment
Malignant tumour
10.0
13.6
28
37
UJF32
NOMESCO Finland
Coloscopy
5.3
13.4
52
166
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
+∞
12.8
12
*
A03FA01
ATC
metoclopramide; systemic, rectal
5.3
12.7
47
140
JN4BD
NOMESCO Finland
Extensive body CT
7.0
12.1
32
62
A04AA02
ATC
granisetron; systemic, transdermal
10.1
11.9
24
30
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
13.5
11.7
20
18
A07EA02
ATC
hydrocortisone; rectal
121.9
10.6
11
*
H02AB06
ATC
prednisolone; systemic
4.0
10.2
66
319
H02AB02
ATC
dexamethasone; systemic
6.1
10.1
29
62
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
7.5
10.0
24
40
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
10.3
9.8
19
22
ZX120
NOMESCO Finland
Intravenous
6.6
9.2
24
45
A49.9
ICD-10 Finland
Bacterial infection, unspecified
6.2
8.8
24
48
A02BC02
ATC
pantoprazole; systemic
4.0
8.5
82
509
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
4.6
8.5
32
92
TPX10
NOMESCO Finland
Implantation of vascular injection port
16.3
8.5
13
9
JN4AD
NOMESCO Finland
Body CT examination
6.5
8.5
22
41
TPH04
NOMESCO Finland
Cathetrisation of vein
4.3
8.1
33
102
L01BC06
ATC
capecitabine; oral
10.8
8.1
15
16
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
16.7
7.9
12
8
A07EA06
ATC
budesonide; oral, local oral
20.3
7.8
11
6
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.5
7.6
45
188
L04AX01
ATC
azathioprine; systemic
17.4
7.4
11
7
UJF30
NOMESCO Finland
Ileoscopy through colon
5.5
6.9
20
43
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
43.0
6.9
8
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
6.6
6.8
17
30
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
13.5
6.8
11
9
Z51.5
ICD-10 Finland
Palliative care
6.3
6.7
17
31
P01AB01
ATC
metronidazole; oral, rectal
3.0
6.4
52
263
B01AB05
ATC
enoxaparin; parenteral
3.1
6.2
42
189
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.2
6.2
24
70
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
7.2
6.1
14
22

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
27
44
7.79
16.82
1.4
1.2
—
—
—
0
0
37
89
5.74
15.60
6.4
4.3
29.50
8.24
ug/l
0.77
32
70
57
225
4.15
12.51
8.1
4.2
—
—
—
0
0
30
75
5.11
11.86
1.6
1.1
—
—
—
0
0
90
507
5.10
11.64
22.9
9.7
4.20
4.06
e9/l
0.22
84
449
44
152
4.14
11.48
8.9
2.6
0.79
0.83
mmol/l
1.97
44
142
64
288
3.89
11.35
12.5
4.8
—
—
—
0
0
81
445
4.03
10.30
12.5
5.8
0.16
0.20
e9/l
1.40
74
402
79
431
3.89
10.06
11.9
5.5
0.03
0.04
e9/l
0.60
71
384
79
431
3.89
10.06
12.0
5.4
0.62
0.59
e9/l
0.35
71
382
70
355
3.63
9.95
13.4
4.2
32.72
36.01
g/l
3.30
70
337
80
442
3.90
9.95
11.8
5.4
1.72
1.84
e9/l
0.54
73
401
33
110
3.85
8.80
1.3
1.3
—
—
—
0
0
78
455
3.40
8.26
19.9
5.6
10.80
10.96
umol/l
0.06
78
432
70
389
3.16
7.94
13.6
7.2
1.20
1.21
mmol/l
1.44
64
331
66
355
3.12
7.93
11.3
5.8
1.20
1.22
mmol/l
1.36
66
327
24
71
4.04
7.48
1.5
1.4
—
—
—
0
0
23
70
3.88
6.87
4.7
3.8
3.15
1.00
%
0.74
13
22
49
240
2.86
6.71
9.0
3.8
7.40
7.40
ph
—
7
44
31
117
3.29
6.70
10.9
6.1
1.01
1.05
mmol/l
0.33
31
107
32
126
3.16
6.43
4.4
1.9
—
—
—
0
0
47
243
2.62
5.61
3.7
3.1
—
—
—
0
0
45
234
2.55
5.24
19.8
6.3
—
—
—
0
0
35
165
2.64
4.94
4.3
3.1
45.50
105.66
ng/l
0.64
26
120
23
87
3.07
4.86
5.0
3.7
—
—
—
0
0
27
114
2.81
4.69
3.1
2.3
24.71
21.30
%
0.40
22
96
26
108
2.84
4.65
1.5
1.5
—
—
—
0
0
43
230
2.42
4.62
3.4
3.9
0.00
0.00
estimate
0.00
15
77
19
66
3.27
4.60
4.9
3.9
0.18
0.20
%
0.04
11
20
26
109
2.81
4.57
9.8
6.8
104.31
103.94
mmol/l
0.14
26
101
25
103
2.84
4.54
2.8
1.3
—
—
—
0
0
11
26
4.59
4.47
1.2
1.1
—
—
—
0
0
50
290
2.32
4.44
4.4
2.9
19.25
34.95
e6/l
0.74
45
228
30
142
2.52
4.14
3.9
2.4
2.00
2.12
e6/l
0.05
21
77
37
194
2.36
4.09
4.0
3.7
—
—
—
0
0
60
389
2.18
3.94
21.5
8.6
0.00
0.00
e9/l
0.00
50
317
19
73
2.93
3.88
6.1
6.7
—
—
—
0
0
53
330
2.16
3.83
5.4
3.4
51.48
52.87
e6/l
0.02
47
245
12
35
3.72
3.73
12.1
8.5
—
—
—
0
0
19
75
2.85
3.70
4.7
2.8
71.00
71.97
e9/l
0.03
13
60
63
424
2.12
3.68
4.3
3.8
0.00
0.00
estimate
0.00
15
80
17
64
2.96
3.59
4.7
3.8
0.75
0.54
%
—
10
13
63
428
2.09
3.54
5.6
5.3
0.00
0.00
estimate
0.00
14
80
80
597
2.22
3.49
5.4
4.3
—
—
—
0
0
52
331
2.07
3.46
23.5
8.3
1.24
1.26
inr
0.06
17
94
43
255
2.12
3.45
4.5
2.7
—
—
—
0
0
17
67
2.82
3.31
1.3
1.3
—
—
—
0
0
51
327
2.04
3.29
3.7
3.7
—
—
—
0
0
63
437
2.02
3.25
4.3
3.8
0.00
0.00
estimate
0.00
15
82
16
63
2.80
3.12
4.7
4.0
0.00
0.00
%
—
9
17
8
16
5.30
3.11
2.9
2.8
—
—
—
0
0
14
52
2.94
3.02
1.8
2.5
—
—
—
0
0
84
665
2.08
2.79
5.7
3.9
13.40
12.30
mm/h
0.28
78
610
7
14
5.26
2.77
2.4
1.2
—
—
—
0
0
12
43
3.01
2.74
6.5
5.2
23.42
25.49
mmol/l
0.83
12
43
27
148
2.09
2.58
1.5
1.5
—
—
—
0
0
6
11
5.69
2.58
4.7
3.7
2.43
3.95
nmol/l
—
6
11
5
7
7.41
2.57
1.4
1.6
—
—
—
0
0
20
97
2.30
2.57
2.8
1.5
—
—
—
0
0
31
180
2.00
2.54
1.7
1.8
—
—
—
0
0
5
8
6.48
2.39
5.6
4.1
—
—
—
0
0
49
338
1.81
2.36
3.0
2.0
—
—
—
0
0
6
13
4.81
2.30
1.5
1.5
—
—
—
0
0
34
211
1.88
2.28
1.6
1.5
20.67
20.33
nmol/l
0.04
34
187
12
48
2.68
2.27
3.0
1.5
1.26
0.90
g/l
0.75
12
43
32
195
1.90
2.26
6.9
4.7
—
—
—
0
0
5
9
5.75
2.23
3.2
1.7
—
—
—
0
0
5
9
5.75
2.23
3.2
2.7
—
—
—
0
0
5
9
5.75
2.23
2.8
2.8
—
—
—
0
0
5
9
5.75
2.23
3.2
1.7
—
—
—
0
0
5
9
5.75
2.23
3.2
1.7
—
—
—
0
0
5
9
5.75
2.23
3.2
1.7
—
—
—
0
0
13
55
2.54
2.22
5.8
3.7
118.77
129.75
g/l
0.86
13
55
11
44
2.67
2.08
3.0
2.5
—
—
—
0
0
49
348
1.73
2.08
2.0
1.9
94.16
93.75
pmol/l
0.02
31
180
14
64
2.36
2.04
3.9
3.8
—
—
—
0
0
100
881
2.36
2.01
41.5
13.3
25.08
22.70
mg/l
0.35
93
676
11
45
2.60
2.00
6.8
4.3
24.31
24.50
mmol/l
0.09
11
45
14
67
2.25
1.85
3.4
3.6
—
—
—
0
0
5
12
4.31
1.84
1.2
1.5
—
—
—
0
0
88
751
1.83
1.80
44.4
16.5
14.36
13.63
%
3.72
88
737
74
603
1.68
1.78
5.0
3.8
—
—
—
0
0
39
270
1.69
1.77
5.3
2.2
—
—
—
0
0
28
177
1.78
1.74
1.5
1.8
368.22
442.55
pmol/l
1.25
23
148
11
49
2.38
1.70
2.5
2.8
1.22
1.27
%
0.09
11
49
21
331
0.55
1.68
2.7
3.0
—
—
—
0
0
5
15
3.44
1.54
8.8
2.1
67.40
61.53
%
—
5
15
9
37
2.56
1.52
5.7
5.1
—
—
—
0
0
6
22
2.82
1.45
1.3
1.5
—
—
—
0
0
5
16
3.22
1.45
6.8
2.3
8.48
8.34
kpa
—
5
16
5
16
3.22
1.45
6.8
2.3
5.20
4.96
kpa
—
5
16
12
61
2.08
1.39
7.3
5.0
—
—
—
0
0
8
36
2.31
1.27
9.4
10.1
22.15
25.66
mmol/l
—
8
30
5
19
2.71
1.23
2.2
2.5
6.32
7.92
kpa
—
5
19
36
266
1.52
1.20
2.5
2.9
7.06
8.05
mmol/l
0.59
31
229
101
934
1.90
1.12
42.1
15.4
81.59
78.93
umol/l
0.18
101
934
33
243
1.51
1.11
1.3
1.4
—
—
—
0
0
90
809
1.59
1.10
38.8
14.2
37.06
40.22
%
1.89
62
607
98
901
1.75
1.07
39.9
15.0
139.16
139.79
mmol/l
1.88
98
880
43
338
1.44
1.04
4.3
3.8
17.64
45.38
ng/l
1.64
35
227
98
905
1.71
1.00
40.7
14.9
3.96
3.98
mmol/l
0.33
98
883
86
772
1.51
0.99
46.0
17.3
331.71
332.36
g/l
0.26
86
767
7
36
2.01
0.99
4.1
3.0
—
—
—
0
0
6
29
2.13
0.91
1.0
3.1
—
—
—
0
0
32
244
1.44
0.90
3.6
3.6
—
—
—
0
0
33
260
1.38
0.77
3.5
3.8
5.18
7.94
mg/mmol
0.51
24
166
9
55
1.69
0.76
2.3
3.0
4.37
4.48
pmol/l
—
9
50
5
25
2.05
0.73
1.2
3.5
—
—
—
0
0
83
891
0.73
0.68
4.5
4.8
2.54
2.72
mmol/l
1.05
74
821
31
247
1.35
0.67
2.7
3.0
2010.34
318.40
mg/l
0.39
21
158
5
28
1.82
0.67
1.0
1.3
—
—
—
0
0
81
867
0.76
0.58
4.2
4.3
1.30
1.46
mmol/l
3.38
72
801
9
61
1.52
0.55
1.2
1.2
—
—
—
0
0
88
825
1.32
0.52
5.0
4.5
1.93
1.90
mu/l
0.10
82
751
24
192
1.32
0.50
1.5
1.3
9.50
0.91
u/ml
—
8
52
7
47
1.52
0.48
1.1
1.1
—
—
—
0
0
102
983
1.46
0.46
54.4
19.6
30.34
30.28
pg
0.11
102
970
102
983
1.46
0.46
54.5
19.6
91.28
90.96
fl
0.28
102
970
102
984
1.45
0.46
55.1
19.8
128.33
135.53
g/l
4.59
102
969
78
831
0.79
0.46
4.1
3.9
1.79
1.29
mmol/l
0.66
70
763
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
5
35
1.45
0.40
1.2
1.4
36.46
22.88
iu/l
—
5
30
9
66
1.40
0.39
8.6
4.8
—
—
—
0
0
83
871
0.81
0.36
4.2
4.3
4.46
4.61
mmol/l
0.35
73
812
14
109
1.33
0.35
1.4
1.2
—
—
—
0
0
7
96
0.71
0.32
1.6
1.6
—
—
—
0
0
7
54
1.32
0.31
1.0
1.2
—
—
—
0
0
8
65
1.25
0.28
4.3
2.4
—
—
—
0
0
12
149
0.78
0.28
1.4
1.3
1.42
8.79
u/ml
—
5
63
27
236
1.19
0.28
4.3
4.0
—
—
—
0
0
14
115
1.25
0.25
2.1
1.4
342.86
642.76
titre
—
7
29
11
88
1.28
0.23
1.5
1.6
—
—
—
0
0
5
38
1.33
0.23
3.8
3.9
3.80
4.12
mmol/l
—
5
31
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
293.00
—
0
6
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
6
48
1.26
0.20
7.3
4.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
9
77
1.18
0.16
1.7
1.4
—
—
—
0
0
12
102
1.20
0.16
2.0
1.7
—
—
—
0
0
94
926
1.10
0.08
34.6
12.6
—
—
—
0
0
8
76
1.06
0.07
1.3
2.1
6.45
12.83
nmol/l
—
8
71
8
77
1.04
0.07
1.8
1.4
—
—
—
0
0
7
84
0.82
0.07
1.1
1.4
—
—
—
0
0
84
854
0.93
0.07
4.7
4.4
6.31
5.91
mmol/l
1.49
77
786
0
9
0.00
0.00
0.0
1.3
—
19.83
—
0
9
0
6
0.00
0.00
0.0
1.0
—
41.17
—
0
6
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
99.70
—
0
7
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
3.0
—
11.95
—
0
6
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
28.80
—
0
5

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: COLITTOX – Toxic colitis

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).