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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Toxic colitis

COLITTOX

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K52.1
  • Cause of death: ICD-10 K52.1

2 out of 7 registries used, show all original rules.

122

4. Check minimum number of events

None

122

5. Include endpoints

None

122

6. Filter based on genotype QC (FinnGen only)

118

Control definitions (FinnGen only)

Control exclude
K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K52
Name in latin
Gastroenteritis toxica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 118 65 53
Unadjusted period prevalence (%) 0.02 0.02 0.02
Median age at first event (years) 60.56 53.93 68.69

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
122
Matched controls
1220
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K52.1
ICD-10 Finland
Toxic gastroenteritis and colitis
+∞
176.1
122
*
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
24.8
23
*
A07EC02
ATC
mesalazine; oral, rectal
68.5
24.2
27
5
UJF32
NOMESCO Finland
Coloscopy
6.3
23.1
62
172
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
88.5
20.4
22
*
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
9.1
19.5
27
37
A03FA01
ATC
metoclopramide; systemic, rectal
5.3
18.5
57
173
A04AA02
ATC
granisetron; systemic, transdermal
8.4
18.2
27
40
130
Kela drug reimbursment
Malignant tumour
6.1
15.8
33
70
JN4BD
NOMESCO Finland
Extensive body CT
6.0
15.6
33
71
H02AB02
ATC
dexamethasone; systemic
5.5
15.1
36
86
K51.5
ICD-10 Finland
Left sided colitis
+∞
14.9
14
*
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
+∞
14.9
14
*
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
+∞
14.9
14
*
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
+∞
14.9
14
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
7.7
14.2
22
34
JN4AD
NOMESCO Finland
Body CT examination
5.8
13.9
30
65
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.5
13.9
32
74
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.2
13.5
55
200
UJF30
NOMESCO Finland
Ileoscopy through colon
6.3
12.6
24
46
A04AA01
ATC
ondansetron; systemic, rectal
6.0
12.0
24
48
R11
ICD-10 Finland
Nausea and vomiting
5.5
11.8
26
57
Z51.5
ICD-10 Finland
Palliative care
5.7
11.5
24
50
ZX120
NOMESCO Finland
Intravenous
5.3
11.4
26
59
N02AA05
ATC
oxycodone; systemic
3.9
10.8
43
150
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.9
10.3
39
131
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.6
10.2
28
74
A07EA02
ATC
hydrocortisone; rectal
44.0
10.2
12
*
JN3AD
NOMESCO Finland
Abdominal CT examination
4.7
10.0
27
70
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
8.3
9.2
20
28
UGC12
NOMESCO Finland
Flexible bronchoscopy
5.6
9.2
19
39
A07EA06
ATC
budesonide; oral, local oral
20.5
9.2
13
7
A02BC02
ATC
pantoprazole; systemic
4.0
9.0
99
633
L04AX01
ATC
azathioprine; systemic
18.0
8.8
13
8
H02AB06
ATC
prednisolone; systemic
3.2
8.7
77
428
L01BC06
ATC
capecitabine; oral
8.2
8.3
18
25
N02AX02
ATC
tramadol; systemic, rectal
3.0
8.2
67
353
P01AB01
ATC
metronidazole; oral, rectal
3.0
8.2
64
329
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
7.9
8.1
18
26
WZC00
NOMESCO Finland
Treatment plan or consultation
2.9
7.8
60
303
K51
ICD-10 Finland
Ulcerative colitis
+∞
7.4
7
*
TPH04
NOMESCO Finland
Cathetrisation of vein
3.1
7.1
37
149
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.6
7.1
18
44
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.2
6.5
30
112
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.9
6.5
21
62
B01AB05
ATC
enoxaparin; parenteral
2.7
6.4
50
250
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.6
6.3
54
282
TPX10
NOMESCO Finland
Implantation of vascular injection port
7.4
6.2
14
21
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
9.4
6.2
12
14

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
44
101
6.25
19.74
6.6
4.2
25.23
7.56
ug/l
0.75
38
79
29
49
7.45
17.44
1.3
1.2
—
—
—
0
0
65
257
4.27
14.32
7.8
4.2
—
—
—
0
0
33
88
4.77
11.99
1.6
1.1
—
—
—
0
0
47
168
3.92
11.52
8.4
3.0
0.79
0.83
mmol/l
1.77
47
157
79
399
3.78
11.43
12.9
4.6
32.98
35.90
g/l
3.16
79
381
98
574
4.60
11.33
23.9
9.8
4.19
4.08
e9/l
0.19
92
504
86
461
3.93
11.32
12.4
6.1
—
—
—
0
0
89
503
3.84
10.48
12.1
5.9
0.17
0.19
e9/l
0.87
81
449
87
487
3.74
10.35
11.5
5.6
0.03
0.04
e9/l
0.43
78
430
87
488
3.73
10.29
11.6
5.6
0.62
0.59
e9/l
0.60
78
430
88
499
3.74
10.19
11.4
5.6
1.70
1.83
e9/l
0.74
80
449
89
509
3.77
10.16
19.8
6.4
10.68
10.85
umol/l
0.07
89
482
79
446
3.19
8.67
13.3
7.2
1.20
1.22
mmol/l
2.00
72
383
27
80
4.05
8.39
1.6
1.4
—
—
—
0
0
74
411
3.03
8.21
10.8
5.9
1.20
1.22
mmol/l
1.87
74
378
34
124
3.41
7.76
1.3
1.2
—
—
—
0
0
33
127
3.19
6.84
10.3
6.6
1.02
1.06
mmol/l
0.27
33
116
49
236
2.80
6.81
2.1
1.9
3.10
2.87
mg/l
0.32
44
207
35
145
2.98
6.36
4.3
1.8
—
—
—
0
0
24
80
3.49
6.21
4.5
5.3
2.65
0.94
%
0.78
17
32
54
285
2.61
6.14
8.3
4.0
7.41
7.39
ph
—
8
53
53
280
2.58
5.99
3.8
3.0
—
—
—
0
0
15
27
6.18
5.91
1.6
1.3
189.10
262.77
ug/g
—
10
12
31
128
2.91
5.62
3.0
2.4
23.74
21.83
%
0.22
25
109
15
40
4.14
5.27
11.8
9.1
—
—
—
0
0
49
264
2.43
5.17
19.4
6.6
—
—
—
0
0
30
127
2.81
5.17
10.2
6.9
104.53
104.28
mmol/l
0.10
30
127
28
115
2.86
5.09
1.5
1.5
—
—
—
0
0
38
186
2.51
4.89
4.3
3.2
42.64
95.22
ng/l
0.63
28
138
48
263
2.36
4.82
3.5
3.8
0.00
0.00
estimate
-0.00
15
92
26
106
2.85
4.78
3.5
2.1
35.46
28.36
u/l
0.56
26
88
68
434
2.28
4.75
23.8
12.1
1.25
1.24
inr
0.01
21
129
27
114
2.76
4.64
2.8
1.3
—
—
—
0
0
40
206
2.40
4.58
2.9
3.9
1.02
1.02
kg/l
—
6
24
22
86
2.90
4.34
4.4
3.1
73.13
73.64
e9/l
0.02
15
67
20
75
2.99
4.24
4.8
5.4
0.15
0.19
%
0.08
13
27
21
83
2.85
4.06
7.1
7.7
—
—
—
0
0
54
331
2.13
3.99
4.5
2.9
21.94
34.38
e6/l
0.60
49
252
71
483
2.12
3.99
4.2
3.8
0.00
0.00
estimate
-0.00
15
98
71
484
2.12
3.95
5.6
5.2
0.00
0.00
estimate
-0.00
15
95
33
168
2.32
3.81
4.0
2.5
1.94
2.28
e6/l
0.16
24
89
66
442
2.07
3.81
22.6
9.1
0.00
0.00
e9/l
-0.00
55
359
71
494
2.05
3.63
4.2
3.8
0.00
0.00
estimate
-0.00
16
96
58
377
2.03
3.57
5.4
3.4
71.72
55.03
e6/l
0.22
52
270
40
227
2.13
3.53
3.9
3.6
—
—
—
0
0
89
677
2.16
3.53
5.5
4.2
—
—
—
0
0
7
10
7.34
3.41
1.3
1.6
305.43
254.20
u/ml
—
7
5
58
383
1.98
3.36
3.0
2.0
—
—
—
0
0
23
105
2.47
3.35
2.7
1.5
—
—
—
0
0
52
331
2.00
3.34
8.8
3.3
2.33
2.35
mmol/l
0.52
47
293
11
29
4.06
3.28
1.2
1.1
—
—
—
0
0
7
11
6.67
3.23
4.1
3.7
2.53
3.95
nmol/l
—
7
11
18
74
2.68
3.22
4.6
5.4
0.71
0.81
%
0.07
12
26
14
51
2.97
3.10
3.0
2.5
—
—
—
0
0
14
52
2.91
3.00
7.4
4.8
23.43
25.53
mmol/l
1.02
14
52
29
155
2.14
2.94
1.5
1.6
—
—
—
0
0
17
72
2.58
2.88
4.5
5.6
0.00
0.08
%
—
10
24
33
188
2.04
2.83
1.7
1.8
—
—
—
0
0
17
73
2.54
2.80
1.3
1.3
—
—
—
0
0
92
740
1.99
2.72
5.6
3.9
13.55
12.39
mm/h
0.33
86
674
15
62
2.62
2.66
1.7
2.3
—
—
—
0
0
7
15
4.88
2.64
2.4
3.3
1.14
2.20
%
—
7
15
8
20
4.20
2.61
2.9
2.6
—
—
—
0
0
45
294
1.84
2.55
4.7
2.7
—
—
—
0
0
7
16
4.57
2.51
2.4
1.2
—
—
—
0
0
45
298
1.81
2.43
5.2
2.3
—
—
—
0
0
33
199
1.90
2.38
1.5
1.7
372.00
438.68
pmol/l
1.17
28
165
6
13
4.79
2.30
2.8
2.4
—
—
—
0
0
12
48
2.66
2.26
7.7
4.2
24.17
24.61
mmol/l
0.24
12
48
111
980
2.47
2.23
40.9
13.6
24.44
22.56
mg/l
0.29
104
758
5
9
5.74
2.23
1.4
1.4
—
—
—
0
0
5
9
5.74
2.23
3.2
1.3
21.08
12.06
ug/l
—
5
9
8
24
3.49
2.22
1.3
1.5
—
—
—
0
0
14
62
2.42
2.17
6.6
3.7
117.93
129.06
g/l
0.96
14
62
13
56
2.48
2.13
2.3
2.8
1.18
1.22
%
0.06
13
56
13
56
2.48
2.13
2.3
2.8
0.69
0.69
%
0.03
13
56
6
15
4.15
2.06
1.5
1.5
—
—
—
0
0
83
676
1.71
2.01
5.1
3.9
—
—
—
0
0
5
11
4.69
1.96
2.8
2.8
—
—
—
0
0
5
11
4.69
1.96
5.6
3.3
—
—
—
0
0
54
396
1.65
1.95
2.1
1.9
95.58
94.47
pmol/l
0.06
33
202
5
12
4.29
1.84
1.2
1.5
—
—
—
0
0
5
12
4.29
1.84
2.4
2.4
—
—
—
0
0
12
55
2.31
1.74
3.0
1.5
1.26
0.95
g/l
0.61
12
50
15
76
2.11
1.73
3.3
3.6
—
—
—
0
0
10
41
2.56
1.69
5.3
4.7
—
—
—
0
0
6
19
3.27
1.68
6.3
2.2
7.78
8.25
kpa
—
6
19
15
77
2.08
1.68
4.4
3.8
—
—
—
0
0
13
67
2.05
1.44
6.8
4.8
—
—
—
0
0
50
382
1.52
1.42
4.3
3.8
17.06
44.81
ng/l
2.01
40
261
25
363
0.61
1.39
3.0
3.1
—
—
—
0
0
8
34
2.45
1.32
1.5
3.2
—
—
—
0
0
37
269
1.54
1.31
1.3
1.4
—
—
—
0
0
5
18
2.85
1.30
8.8
3.1
67.40
63.67
%
—
5
18
97
864
1.60
1.26
46.7
16.7
14.38
14.77
%
0.90
97
852
112
1037
1.98
1.25
43.2
15.9
80.92
78.87
umol/l
0.15
112
1037
37
272
1.52
1.24
3.7
3.5
—
—
—
0
0
5
19
2.70
1.23
6.8
2.2
5.20
5.00
kpa
—
5
19
40
302
1.48
1.17
2.6
3.0
7.11
7.95
mmol/l
0.50
32
258
109
1006
1.78
1.15
40.5
15.4
139.02
139.81
mmol/l
2.30
109
979
28
198
1.54
1.11
2.0
1.7
1.95
1.25
mg/l
0.43
22
161
5
21
2.44
1.10
2.2
2.4
6.42
7.92
kpa
—
5
21
109
1010
1.74
1.08
41.1
15.4
3.97
3.97
mmol/l
0.07
109
981
94
849
1.47
0.97
46.5
17.7
331.19
332.26
g/l
0.52
94
844
6
29
2.12
0.90
1.8
1.5
48.27
10.42
mg/l
—
6
29
8
43
1.92
0.89
3.7
3.6
—
—
—
0
0
18
122
1.56
0.86
1.4
1.2
—
—
—
0
0
10
58
1.79
0.82
2.2
2.9
4.31
4.45
pmol/l
—
10
52
37
295
1.36
0.78
3.4
3.7
5.05
8.02
mg/mmol
0.60
25
191
35
282
1.34
0.69
2.7
3.1
1919.96
279.27
mg/l
0.40
22
183
99
922
1.39
0.69
5.2
4.5
1.89
1.89
mu/l
0.01
92
840
5
28
1.82
0.67
1.0
1.3
—
—
—
0
0
5
28
1.82
0.67
1.6
1.5
4.00
2.50
e6/l
—
5
22
5
29
1.75
0.64
1.0
3.1
—
—
—
0
0
18
131
1.44
0.63
2.0
1.4
460.00
598.79
titre
—
8
33
113
1089
1.51
0.55
55.4
20.3
37.92
40.31
%
3.12
103
1034
93
985
0.77
0.55
4.8
4.9
2.51
2.74
mmol/l
1.50
81
909
12
83
1.49
0.54
1.5
1.4
—
—
—
0
0
11
75
1.51
0.53
7.4
4.5
—
—
—
0
0
32
266
1.28
0.50
4.6
3.9
—
—
—
0
0
113
1091
1.48
0.46
56.3
20.2
127.85
135.57
g/l
5.87
113
1075
113
1090
1.50
0.46
55.4
20.1
91.46
90.97
fl
0.52
113
1076
113
1090
1.50
0.46
55.3
20.0
30.43
30.29
pg
0.33
113
1076
91
960
0.80
0.45
4.5
4.4
1.30
1.47
mmol/l
3.65
79
888
87
922
0.80
0.45
4.3
4.0
1.76
1.29
mmol/l
0.67
76
848
7
51
1.39
0.45
1.1
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
5
36
1.41
0.38
1.2
1.4
36.46
22.52
iu/l
—
5
31
10
72
1.42
0.38
3.8
2.3
—
—
—
0
0
9
70
1.31
0.37
1.2
1.2
—
—
—
0
0
13
166
0.76
0.36
1.4
1.3
1.42
9.54
u/ml
—
5
69
25
211
1.23
0.35
1.5
1.3
8.56
0.88
u/ml
—
9
56
7
54
1.31
0.31
7.1
4.6
—
—
—
0
0
14
113
1.27
0.28
1.9
1.7
—
—
—
0
0
93
965
0.85
0.27
4.5
4.4
4.42
4.64
mmol/l
0.61
80
901
9
76
1.20
0.25
10.9
4.1
1.22
1.22
mmol/l
—
9
70
5
38
1.33
0.23
5.0
1.8
—
—
—
0
0
8
100
0.79
0.22
1.6
1.6
—
—
—
0
0
105
1023
1.19
0.21
34.7
12.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
293.00
—
0
6
0
10
0.00
0.21
0.0
2.7
—
11.08
—
0
10
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
11
91
1.23
0.18
1.5
1.6
—
—
—
0
0
7
61
1.16
0.18
1.0
1.2
—
—
—
0
0
19
210
0.89
0.13
2.5
2.9
0.84
0.74
ug/l
0.19
14
139
10
87
1.16
0.10
2.2
1.4
—
—
—
0
0
8
91
0.87
0.07
1.1
1.4
—
—
—
0
0
94
950
0.95
0.03
4.9
4.4
6.37
5.92
mmol/l
1.80
85
871
90
904
0.98
0.00
6.5
5.6
41.69
39.60
mmol/mol
1.06
83
842
0
9
0.00
-0.00
0.0
1.3
—
19.83
—
0
9
0
8
0.00
-0.00
0.0
1.3
—
227.47
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
28.80
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
96.86
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
41.17
—
0
6
8
81
0.99
-0.00
1.3
2.1
6.45
13.06
nmol/l
—
8
76
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
59.80
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: COLITTOX – Toxic colitis

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).