No definition available.
Intrahepatic Cholestasis of Pregnancy (ICP) , excluding more controls
O15_ICP_EXMORE
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleonly females |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
- Control exclude
- !(O15_DELIVERY, O15_DELIVERY_PROXY)
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF3
- Parent code in ICD-10
- O26
- Name in latin
- Morbositates hepatis in graviditate, intra labores et/sive in puerperio
Similar endpoints
↥List of similar endpoints to
Intrahepatic Cholestasis of Pregnancy (ICP) , excluding more controls
based on the number of shared cases.
Similar with more cases:
- Intrahepatic Cholestasis of Pregnancy (ICP)
- Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8
- Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8, excluding more controls
- Pregnancy, childbirth and the puerperium
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 19565 | 19565 | - |
| Only index persons | 19357 | 19357 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.56 | 0.56 | - |
| Only index persons | 0.71 | 0.71 | - |
| Median age at first event (years) | |||
| Whole population | - | 29.97 | - |
| Only index persons | - | 29.97 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2970 | 2970 | - |
| Unadjusted period prevalence (%) | 1.01 | 1.01 | - |
| Median age at first event (years) | 30.33 | 30.33 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2669
- Matched controls
- 26689
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
16384.0
323.0
2068
*
A05AA02
ATC
ursodeoxycholic acid; oral
126.0
323.0
804
91
6467A
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Liver disorders in pregnancy[HEPATOSIS GRAVIDARUM]
+∞
323.0
680
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.5
65.8
338
1059
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
2.6
49.6
406
1720
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.5
44.2
403
1802
O80.8
ICD-10 Finland
Other single spontaneous delivery
2.1
31.1
377
1909
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.7
26.6
633
4069
O30.0
ICD-10 Finland
Twin pregnancy
3.0
25.1
149
512
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
2.4
24.0
206
883
W84
ICPC
Pregnancy high risk
2.1
22.0
276
1406
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
1.5
21.5
1040
7927
63900
ICD-8 Finland
Other toxaemias of pregnancy and the puerperium, Pruritus
16.4
21.4
34
21
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
2.5
18.7
154
643
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
1.6
17.8
575
3958
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
1.6
17.3
585
4068
63998
ICD-8 Finland
Other toxaemias of pregnancy and the puerperium, Alia definitae
22.0
16.8
24
11
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
3.3
16.4
82
251
K76.9
ICD-10 Finland
Liver disease, unspecified
5.2
15.4
47
91
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
0.6
14.8
187
3172
5742A
ICD-9 Finland
Cholelithiasis, Calculus of gallbladder without mention of cholecystitis[CHOLECYSTOLITHIASIS SINE CHOLECYSTITIDE,SINE OBSTR]
4.3
14.8
54
127
L29.9
ICD-10 Finland
Pruritus, unspecified
3.1
14.7
79
257
O60
ICD-10 Finland
Preterm labour and delivery
2.0
14.7
180
911
8811
FHL
Cesarean section
1.8
13.5
236
1356
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
3.5
13.2
61
177
A10BX01
ATC
guar gum; systemic
3.8
12.7
53
142
MAC96
NOMESCO Finland
Other induction or advancement of labour
1.9
12.5
182
983
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
1.5
12.4
564
4146
MAA00
NOMESCO Finland
Amniocentesis
2.0
12.1
152
776
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
1.6
11.8
359
2412
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
1.8
11.6
211
1232
6510B
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, SYNNYTYKSEN AIKANA]
4.1
11.2
42
103
XMA22
NOMESCO Finland
General examination of pregnant woman
1.5
11.1
367
2516
S02
ICPC
Pruritus
2.3
10.2
94
421
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
2.0
9.8
124
636
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
1.9
9.8
150
828
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
1.3
9.6
979
8179
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
9.6
255
1656
6510A
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, RASKAUDEN AIKANA]
5.0
9.4
29
59
6467X
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Liver disorders in pregnancy[HEPATOPATHIA ALIA GRAVIDARUM]
+∞
9.4
9
*
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
1.4
9.1
625
4918
G03DA04
ATC
progesterone; systemic, rectal, vaginal
1.9
8.9
133
729
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
1.6
8.9
221
1411
L04AX01
ATC
azathioprine; systemic
2.0
8.3
100
506
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
1.5
8.2
268
1828
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
8.0
977
8306
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
8.9
8.0
16
18
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
2.0
7.8
100
518
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
7.5
398
2987
O48
ICD-10 Finland
Prolonged pregnancy
0.5
7.5
79
1410
V230A
ICD-9 Finland
Supervision of high-risk pregnancy, Pregnancy with history of infertility
2.6
7.5
52
203
6488A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Abnormal glucose tolerance
2.4
7.5
60
255
6663
FHL
Cholecystectomy and cholangiography
3.6
7.4
31
86
K83.0
ICD-10 Finland
Cholangitis
4.2
7.3
26
63
K50.9
ICD-10 Finland
Crohn disease, unspecified
2.9
7.2
42
148
B18.2
ICD-10 Finland
Chronic viral hepatitis C
3.3
7.2
34
105
O84.2
ICD-10 Finland
Multiple delivery, all by caesarean section
3.1
7.1
37
122
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
3.9
7.1
27
70
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
2.7
7.0
45
167
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
2.0
6.8
84
433
O82.0
ICD-10 Finland
Delivery by elective caesarean section
1.5
6.7
254
1792
O26.0
ICD-10 Finland
Excessive weight gain in pregnancy
5.2
6.6
19
37
O61.0
ICD-10 Finland
Failed medical induction of labour
2.1
6.6
69
333
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
1.7
6.5
129
777
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
2.0
6.5
78
398
O98.4
ICD-10 Finland
Viral hepatitis complicating pregnancy, childbirth and the puerperium
5.3
6.5
18
34
1413
FHL
Laparoscopy and other therapeutic procedure
2.1
6.4
66
316
G03GB02
ATC
clomifene; oral
1.8
6.4
101
566
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
1.4
6.4
383
2933
O26.5
ICD-10 Finland
Maternal hypotension syndrome
14.3
6.4
10
7
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
3.5
6.4
27
77
O99.80
ICD-10 Finland
The fear of childbirth
1.4
6.4
293
2146
K80.1
ICD-10 Finland
Calculus of gallbladder with other cholecystitis
2.5
6.3
45
181
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
4.3
6.2
21
49
H02AB07
ATC
prednisone; oral
1.4
6.2
261
1881
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
2.0
6.1
70
351
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
809
1182
9.03
307.65
6.2
1.5
10.02
3.99
umol/l
20.04
713
833
282
506
6.05
152.00
1.2
1.3
108.47
108.30
u/ml
0.01
55
136
289
552
5.69
145.70
1.2
1.3
14.08
17.13
u/ml
—
5
17
280
521
5.83
145.15
1.2
1.2
200.63
266.59
u/ml
5.08
230
348
290
559
5.64
144.74
1.2
1.2
—
—
—
0
0
104
144
7.45
71.32
1.1
1.2
—
—
—
0
0
444
2431
1.97
34.44
2.4
2.4
6.01
5.71
umol/l
0.13
396
2063
1428
10880
1.60
33.81
5.0
4.9
9.67
9.33
umol/l
0.67
1343
10245
1111
8183
1.57
29.03
3.6
2.8
33.97
27.78
u/l
4.55
1065
7851
165
660
2.59
27.31
1.5
1.2
74.29
203.06
titre
0.79
14
62
1987
17040
1.50
22.91
7.3
6.3
78.91
70.77
u/l
14.37
1885
16143
2830
26644
2.32
21.61
10.8
7.9
32.16
23.71
u/l
36.75
2787
25999
248
1350
1.91
19.13
1.7
1.8
1.38
1.37
g/l
0.03
229
1267
307
1790
1.80
19.04
2.3
2.5
10.78
10.34
g/l
1.55
282
1661
262
1463
1.87
18.68
2.3
2.1
0.22
0.23
g/l
0.74
245
1383
1294
10885
1.33
12.92
8.1
7.4
0.00
0.00
e9/l
0.58
1083
9051
868
6974
1.35
11.49
2.4
2.3
59.55
55.24
u/l
0.49
823
6553
665
5158
1.37
10.97
3.8
2.9
99.46
99.99
%
0.25
640
4971
1310
11249
1.29
10.50
6.2
5.5
7.86
7.74
%
0.85
1260
10614
1302
11179
1.29
10.41
6.0
5.3
2.84
2.81
%
0.20
1239
10434
1255
10727
1.29
10.38
6.1
5.4
0.74
0.68
%
3.91
1202
10020
975
8061
1.31
10.34
4.4
4.0
36.64
37.03
g/l
1.54
917
7572
45
154
2.95
10.19
1.3
1.3
309.09
165.26
titre
0.43
11
38
49
180
2.75
9.77
1.1
1.1
317.48
290.75
mg/l
0.90
42
166
44
153
2.90
9.70
1.1
1.0
—
—
—
0
0
2008
18330
1.29
9.52
3.2
2.6
38.90
32.30
u/l
3.97
1917
17653
1348
11719
1.28
9.44
6.0
5.2
30.22
30.04
%
0.31
1290
11019
739
5954
1.32
9.25
1.5
1.4
2.08
2.09
g/l
0.04
483
3908
1328
11569
1.27
8.99
5.9
5.1
55.99
56.32
%
0.59
1274
10904
250
1682
1.53
8.78
3.1
4.0
221.03
236.18
u/l
1.01
236
1591
63
291
2.19
7.76
1.0
1.1
1.41
1.43
g/l
0.13
55
264
1401
12428
1.24
7.62
6.0
5.2
1.94
1.97
e9/l
0.85
1293
11301
401
3039
1.37
7.43
1.9
2.1
14.93
14.81
umol/l
0.13
378
2833
45
184
2.47
7.33
1.0
1.1
—
—
—
0
0
1645
14908
1.23
7.12
3.1
3.0
56.81
64.46
ug/l
3.93
1573
14230
271
1936
1.44
7.07
2.5
2.2
35.70
35.62
u/l
0.01
244
1663
1403
12523
1.23
6.96
6.2
5.3
0.18
0.18
e9/l
0.07
1297
11349
2397
22687
1.29
6.92
12.6
11.1
13.41
13.42
%
0.06
2372
22297
319
2358
1.40
6.87
1.9
2.1
24.39
24.43
%
0.02
275
2029
672
5539
1.28
6.80
2.6
2.5
0.16
0.25
e6/l
2.41
502
4087
674
5584
1.27
6.50
2.2
2.0
2.50
2.61
mg/l
0.74
595
4869
357
2713
1.36
6.48
1.9
2.0
2.52
2.51
g/l
0.11
329
2513
1973
18327
1.23
6.33
4.1
3.6
9.60
9.00
mm/h
1.79
1879
17409
735
6173
1.25
6.29
2.7
2.6
35.24
80.11
e6/l
1.10
545
4623
1145
10097
1.22
6.16
2.4
2.2
75.21
74.40
nmol/l
0.48
1084
9558
99
583
1.72
6.05
2.2
2.0
1.14
1.26
g/l
0.62
83
511
154
1015
1.55
6.00
1.3
1.3
—
—
—
0
0
33
130
2.56
5.86
3.0
3.0
8.75
7.30
mg/l
0.53
26
96
76
420
1.83
5.77
4.2
3.4
1035.77
435.64
u/ml
0.33
67
359
1503
13671
1.20
5.69
7.8
7.4
3.82
3.91
e9/l
1.00
1352
12110
54
274
1.99
5.32
1.4
1.3
—
—
—
0
0
2449
23467
1.25
4.96
4.2
4.0
—
—
—
0
0
838
7304
1.21
4.83
1.3
1.3
1.02
1.51
u/ml
1.54
253
2277
521
4329
1.25
4.78
2.3
2.2
9.66
8.48
e6/l
0.27
450
3741
2385
22818
1.23
4.72
8.5
7.6
93.85
93.45
ml/min/173m2
0.50
1995
18733
641
5469
1.22
4.57
1.3
1.3
10.17
8.63
u/ml
0.29
259
2429
2537
24511
1.24
4.12
5.1
5.0
1.64
1.87
mu/l
1.28
2420
23490
626
5406
1.20
3.89
2.1
2.0
683.75
1799.52
umol/l
1.64
561
4881
2289
21927
1.19
3.88
4.6
4.4
14.25
14.21
pmol/l
0.36
2156
20907
475
3995
1.22
3.87
3.2
2.4
94.43
94.41
ug/g
0.00
383
3155
36
180
2.01
3.78
1.3
1.2
50.34
64.73
u/l
0.81
29
122
88
572
1.55
3.77
2.7
1.7
696.00
313.10
titre
—
5
29
653
5677
1.19
3.76
1.3
1.3
24.17
25.18
iu/ml
0.07
199
1838
995
8968
1.16
3.68
4.9
5.0
1.22
1.22
mmol/l
0.26
847
7589
230
1786
1.31
3.66
2.4
2.4
—
—
—
0
0
311
2513
1.27
3.64
2.2
1.9
29.02
28.80
s
0.29
295
2415
878
7845
1.17
3.63
4.6
4.4
1.22
1.22
mmol/l
0.53
834
7214
134
959
1.42
3.59
2.0
2.0
40.43
38.48
u/l
0.58
123
896
2516
24368
1.21
3.50
9.1
8.4
3.88
3.89
mmol/l
0.93
2460
23709
158
2108
0.74
3.49
4.1
4.2
—
—
—
0
0
34
172
1.99
3.48
1.4
1.5
—
—
—
0
0
2506
24287
1.20
3.33
9.0
8.4
139.63
139.60
mmol/l
0.36
2448
23709
41
225
1.83
3.32
1.2
1.1
—
55.04
—
0
5
809
7228
1.16
3.30
1.7
1.7
100.92
100.44
pmol/l
0.10
426
4057
112
805
1.41
2.98
2.6
2.2
3.94
3.62
g/l
1.38
101
751
351
2941
1.22
2.98
2.2
2.3
5.39
4.91
e6/l
0.18
178
1537
44
256
1.73
2.97
1.1
1.2
—
—
—
0
0
568
4974
1.18
2.96
3.6
3.1
7.59
7.68
mmol/l
0.17
499
4374
372
3143
1.21
2.90
2.2
2.2
2.32
1.02
e6/l
0.49
198
1731
614
5421
1.17
2.89
1.5
1.6
1.23
1.33
mmol/l
1.76
544
4764
23
109
2.12
2.84
2.0
1.5
1.57
3.95
u/l
1.29
14
56
675
6011
1.16
2.83
1.9
1.7
0.94
0.82
mg/l
0.70
500
4444
2131
20466
1.15
2.83
4.0
3.8
36.97
37.02
mmol/mol
0.10
2028
19526
438
3767
1.19
2.82
1.4
1.4
20.96
21.13
nmol/l
0.10
393
3391
279
2297
1.24
2.81
2.8
3.5
4.58
4.57
pmol/l
0.01
258
2086
14
53
2.65
2.79
1.3
3.1
13180.67
63.34
mg/l
—
9
38
599
5292
1.17
2.79
1.9
1.9
113.56
136.10
u/l
0.83
578
5056
135
1019
1.34
2.69
6.3
6.7
6.77
6.61
mmol/l
0.13
128
988
476
4148
1.18
2.63
4.1
3.8
11.14
11.04
mg/mmol
0.02
303
2629
110
813
1.37
2.53
1.2
1.3
6.92
7.41
u/ml
0.04
14
140
174
1374
1.28
2.52
1.2
1.3
0.27
0.93
u/ml
1.70
12
109
42
255
1.66
2.48
1.2
1.1
—
—
—
0
0
264
2192
1.22
2.48
1.3
1.3
212.84
147.63
u/ml
0.34
254
2051
144
1112
1.31
2.48
1.7
1.7
—
—
—
0
0
130
990
1.33
2.47
1.4
1.4
—
—
—
0
0
38
225
1.70
2.47
1.0
1.1
8.69
9.97
iu/ml
—
10
59
457
3992
1.17
2.46
3.4
3.2
512.13
538.25
mg/l
0.03
288
2479
108
801
1.36
2.44
1.3
1.3
7.40
6.22
u/ml
—
9
79
103
759
1.37
2.43
1.2
1.3
64.44
39.39
u/ml
—
7
72
308
2614
1.20
2.32
3.0
3.1
0.83
0.83
mmol/l
0.41
293
2474
928
8545
1.13
2.31
1.7
1.7
—
—
—
0
0
183
1473
1.26
2.30
3.1
3.1
1.22
1.23
mmol/l
1.77
167
1282
377
3264
1.18
2.27
1.6
1.6
1.34
1.31
%
0.42
328
2931
33
193
1.72
2.26
1.8
2.5
61.49
62.31
%
0.07
33
193
71
499
1.43
2.22
3.7
3.7
57.21
57.16
%
0.01
71
499
285
2417
1.20
2.18
1.8
2.1
371.83
370.95
nmol/l
0.03
265
2261
332
2855
1.18
2.17
2.3
2.3
311.59
378.69
ng/l
0.42
262
2284
178
2184
0.80
2.15
1.4
1.5
—
—
—
0
0
77
553
1.40
2.15
1.2
1.1
12.11
11.61
au/ml
0.03
12
36
718
6537
1.13
2.14
2.6
2.8
2.34
2.34
mmol/l
0.11
655
5984
1358
12825
1.11
2.09
4.0
3.6
6.10
6.14
mmol/l
0.31
1219
11237
1867
17926
1.11
2.09
4.3
3.8
838.71
1363.88
e6/l
0.26
17
181
29
169
1.72
2.03
2.2
1.4
—
—
—
0
0
1404
13303
1.11
2.00
3.2
3.1
0.00
0.00
estimate
0.69
356
2774
39
248
1.58
1.98
3.6
2.9
28.93
32.57
umol/l
0.86
30
217
19
98
1.94
1.95
1.1
1.2
—
—
—
0
0
78
1049
0.74
1.94
1.3
1.3
2.93
4.06
ug/l
1.54
73
973
124
976
1.28
1.91
2.0
2.1
—
—
—
0
0
117
915
1.29
1.90
1.3
1.3
85.86
28.89
u/ml
—
5
71
463
4135
1.14
1.86
1.6
1.5
19324101.70
47560081.51
pmol/l
0.71
414
3688
2367
23088
1.12
1.82
3.3
3.2
5.53
5.53
mmol/l
0.00
2227
21918
91
1178
0.77
1.76
1.3
1.2
11.44
11.84
u/l
0.11
78
1016
45
306
1.48
1.73
1.2
1.2
—
—
—
0
0
45
306
1.48
1.73
1.2
1.2
—
—
—
0
0
8
30
2.67
1.72
1.3
1.2
—
—
—
0
0
8
30
2.67
1.72
1.0
1.2
—
—
—
0
0
5
13
3.85
1.71
1.0
1.2
—
—
—
0
0
2634
25892
1.15
1.70
10.5
9.5
16.15
17.67
mg/l
2.03
2054
20126
1405
13391
1.09
1.67
4.4
4.3
0.00
0.00
estimate
0.80
365
2883
1414
13482
1.09
1.66
3.2
3.2
0.00
0.00
estimate
1.32
367
2835
37
244
1.52
1.65
1.5
2.4
—
800.11
—
0
9
84
644
1.31
1.62
1.2
1.3
—
—
—
0
0
381
3399
1.14
1.58
2.6
2.2
6722.92
6893.16
u/l
0.04
168
1543
107
855
1.26
1.52
1.6
1.5
—
—
—
0
0
120
973
1.24
1.51
1.7
2.2
3.28
4.34
iu/l
1.59
44
415
160
1337
1.21
1.51
2.2
2.5
1.61
1.68
%
0.40
142
1208
24
146
1.65
1.50
1.2
1.1
95.40
99.12
%
—
10
57
222
1914
1.17
1.48
4.2
4.6
1.05
1.04
mmol/l
0.42
212
1800
65
488
1.34
1.47
1.4
1.5
—
—
—
0
0
2538
24932
1.12
1.46
11.5
9.9
39.46
39.51
%
0.14
2128
20808
37
253
1.47
1.43
2.5
2.8
9.49
112.09
ug/min
3.20
28
170
109
885
1.24
1.38
1.2
1.2
—
—
—
0
0
94
751
1.26
1.37
1.3
1.4
—
—
—
0
0
22
135
1.63
1.35
1.1
1.2
—
—
—
0
0
53
393
1.35
1.32
1.4
1.4
—
—
—
0
0
23
144
1.60
1.32
1.2
1.3
—
—
—
0
0
108
882
1.23
1.31
2.2
2.0
0.22
0.23
g/l
0.16
103
833
35
242
1.45
1.30
1.3
1.1
—
—
—
0
0
118
1422
0.82
1.29
2.2
2.2
—
—
—
0
0
19
114
1.67
1.28
1.9
1.6
1.79
1.95
umol/l
0.53
19
108
35
243
1.45
1.27
1.3
1.1
—
—
—
0
0
22
138
1.60
1.26
1.6
1.7
2.33
2.64
mg/l
0.43
22
132
101
825
1.23
1.23
1.8
2.2
55.45
68.92
ng/l
0.59
86
731
35
491
0.71
1.22
1.5
1.4
32.56
30.58
nmol/l
0.15
28
442
8
37
2.17
1.21
1.0
1.7
—
—
—
0
0
8
37
2.17
1.21
1.0
1.7
—
—
—
0
0
120
1001
1.21
1.20
2.4
2.2
67.18
67.54
g/l
0.26
112
937
35
247
1.42
1.19
1.3
1.1
—
—
—
0
0
35
247
1.42
1.19
1.3
1.1
—
—
—
0
0
35
247
1.42
1.19
1.3
1.1
—
—
—
0
0
336
3037
1.12
1.17
1.2
1.2
166.58
158.80
iu/ml
0.13
135
1278
70
553
1.27
1.15
3.4
3.3
23.80
24.12
mmol/l
0.37
59
490
145
1237
1.18
1.15
1.5
1.6
—
—
—
0
0
69
546
1.27
1.13
1.4
1.3
332.06
331.38
ug/g
0.01
32
257
22
143
1.54
1.11
1.2
1.1
99.80
103.18
%
—
10
57
2456
24163
1.09
1.11
3.4
3.3
4.79
4.88
mmol/l
5.35
2362
23214
696
6541
1.08
1.09
2.3
2.3
21.44
22.12
ng/l
0.04
235
2417
122
1032
1.19
1.08
1.1
1.1
8.55
5.30
u/ml
0.17
17
171
33
236
1.40
1.06
1.2
1.2
—
—
—
0
0
376
3443
1.11
1.05
1.6
1.5
—
—
—
0
0
343
3129
1.11
1.03
1.7
1.6
—
—
—
0
0
13
75
1.74
1.02
33.8
25.0
118.08
116.94
ug/l
0.02
13
63
33
238
1.39
1.02
1.2
1.2
—
—
—
0
0
103
863
1.20
1.02
2.0
2.6
4.83
4.66
kpa
0.26
98
832
41
307
1.34
1.02
1.1
1.5
—
2933.33
—
0
6
65
520
1.26
1.00
1.3
1.2
1.33
2.93
u/ml
1.89
21
167
292
2646
1.11
1.00
1.7
1.6
1151.06
1208.31
nmol/l
0.56
236
2171
5
23
2.18
0.98
1.0
1.1
—
—
—
0
0
32
232
1.38
0.97
2.3
2.6
1.41
1.48
%
0.06
27
180
0
30
0.00
0.97
0.0
1.1
—
—
—
0
0
162
1418
1.15
0.96
1.8
1.6
3.07
3.45
mg/l
0.28
118
941
17
108
1.58
0.96
1.4
1.8
—
—
—
0
0
0
31
0.00
0.96
0.0
1.1
—
—
—
0
0
12
69
1.74
0.96
1.1
1.1
—
—
—
0
0
767
7273
1.07
0.95
3.4
3.4
0.01
0.00
estimate
0.53
362
2846
228
2046
1.12
0.93
1.8
1.8
—
—
—
0
0
73
599
1.22
0.91
2.1
2.1
10.40
9.87
mg/l
0.22
68
568
2914
29002
1.25
0.91
16.2
14.2
266.92
267.53
e9/l
0.22
2874
28592
100
848
1.19
0.90
1.5
1.6
0.01
22.47
iu/ml
0.51
14
150
61
492
1.24
0.90
1.2
1.1
—
—
—
0
0
62
502
1.24
0.88
1.3
1.2
2.13
4.84
u/ml
2.55
24
189
31
228
1.36
0.88
1.2
1.2
—
—
—
0
0
2466
24324
1.08
0.88
3.5
3.5
2.89
2.95
mmol/l
3.38
2354
23199
21
299
0.70
0.86
1.5
1.4
—
—
—
0
0
34
256
1.33
0.84
1.3
1.5
—
—
—
0
0
39
300
1.30
0.84
1.8
2.0
17.54
17.01
%
0.33
16
148
25
179
1.40
0.84
1.1
1.1
—
—
—
0
0
34
257
1.33
0.83
1.3
1.5
—
—
—
0
0
17
113
1.51
0.82
1.2
1.2
—
—
—
0
0
34
258
1.32
0.81
1.3
1.5
—
—
—
0
0
18
122
1.48
0.80
1.2
1.1
—
—
—
0
0
28
208
1.35
0.77
2.6
3.0
—
—
—
0
0
44
349
1.26
0.77
1.9
1.6
14157.81
7179.80
e6/l
0.34
31
257
17
115
1.48
0.76
1.1
1.1
—
—
—
0
0
6
34
1.77
0.76
1.0
1.3
—
—
—
0
0
42
332
1.27
0.76
1.1
1.1
93.98
93.36
%
0.06
42
307
2341
23085
1.07
0.75
3.1
3.0
1.09
1.17
mmol/l
8.31
2255
22148
1105
10677
1.06
0.74
3.2
3.1
—
—
—
0
0
34
262
1.30
0.74
1.3
1.5
—
—
—
0
0
85
726
1.18
0.74
1.1
1.1
1.83
1.30
u/ml
0.20
20
184
34
263
1.30
0.73
1.3
1.5
—
—
—
0
0
228
2082
1.10
0.72
2.3
2.3
19.59
23.09
au/ml
0.27
11
171
9
56
1.61
0.72
1.9
1.4
—
—
iu/ml
—
0
0
10
159
0.63
0.72
1.8
1.5
20.20
25.15
umol/l
—
10
152
2437
24074
1.07
0.71
3.4
3.3
1.55
1.55
mmol/l
0.15
2345
23089
26
194
1.34
0.71
1.7
1.6
48.59
45.77
%
0.12
17
109
9
143
0.63
0.69
1.1
1.7
—
—
—
0
0
9
143
0.63
0.69
1.1
1.7
—
—
—
0
0
9
143
0.63
0.69
1.1
1.7
—
—
—
0
0
2914
29028
1.20
0.68
16.2
14.2
6.65
6.75
e9/l
1.50
2877
28573
2914
29029
1.20
0.68
16.2
14.2
4.45
4.45
e12/l
0.01
2878
28604
15
102
1.47
0.67
1.5
1.4
—
—
—
0
0
5
92
0.54
0.67
4.4
2.6
—
—
—
0
0
48
393
1.23
0.66
1.0
1.2
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
26
197
1.32
0.65
2.0
1.6
126.24
117.07
%
0.28
26
188
34
268
1.27
0.65
1.3
1.5
—
—
—
0
0
30
233
1.29
0.64
1.4
1.3
—
—
—
0
0
99
868
1.15
0.64
1.1
1.1
2.19
1.54
u/ml
0.32
35
312
171
1551
1.11
0.64
8.6
8.2
1.07
1.05
inr
0.19
32
306
14
201
0.70
0.64
1.1
1.1
—
—
—
0
0
47
387
1.22
0.63
3.0
1.9
111.22
234.62
ug/l
1.50
38
332
72
618
1.17
0.62
1.1
1.1
1.05
4.90
u/ml
5.73
30
241
50
599
0.83
0.62
1.2
1.2
—
—
—
0
0
10
63
1.59
0.61
1.2
1.1
—
—
—
0
0
16
222
0.72
0.61
1.6
1.4
—
—
—
0
0
12
175
0.68
0.60
1.2
1.7
—
—
—
0
0
69
801
0.86
0.60
4.8
7.3
24.30
24.18
mmol/l
0.13
62
749
152
1676
0.90
0.60
2.0
2.2
76.54
79.35
ml/min/173m2
0.43
52
592
127
1139
1.12
0.59
2.7
3.0
72.66
71.35
ng/l
0.07
118
1025
80
917
0.87
0.59
1.6
1.8
11.39
4.60
ug/l
0.88
73
810
2914
29041
1.18
0.58
16.3
14.2
132.35
133.08
g/l
3.54
2899
28861
51
428
1.19
0.58
2.7
1.9
—
—
—
0
0
51
428
1.19
0.58
2.7
1.9
3.64
3.77
g/l
0.35
40
296
51
428
1.19
0.58
2.7
1.9
6.83
7.14
g/l
0.87
43
327
59
502
1.18
0.57
3.6
5.2
1.71
1.81
%
0.15
54
465
113
1010
1.12
0.57
1.5
1.6
—
—
—
0
0
15
207
0.72
0.56
1.5
2.1
13.14
12.77
%
—
7
118
44
365
1.21
0.56
2.0
1.7
—
—
—
0
0
14
98
1.43
0.56
1.1
1.5
—
—
u/ml
—
0
0
287
2685
1.08
0.56
1.6
1.7
—
—
—
0
0
353
3330
1.07
0.55
1.3
1.3
28.24
27.68
iu/l
0.11
316
2935
11
159
0.69
0.54
1.8
2.8
939.00
818.49
e6/l
—
6
70
27
339
0.79
0.54
1.0
1.1
—
—
—
0
0
20
151
1.33
0.54
2.1
1.5
44.28
45.45
%
0.04
15
81
9
134
0.67
0.51
1.9
2.1
—
—
—
0
0
6
40
1.50
0.51
1.2
1.2
—
—
—
0
0
651
6267
1.05
0.51
2.0
1.9
—
—
—
0
0
49
417
1.18
0.50
2.7
1.9
2.72
3.02
g/l
1.83
43
309
300
2829
1.07
0.49
1.9
1.8
—
—
—
0
0
30
244
1.23
0.48
4.2
4.0
32.28
49.47
mg/l
0.46
24
203
118
1071
1.11
0.48
2.7
3.1
1.33
1.75
mmol/l
0.56
90
862
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
33
272
1.22
0.47
3.3
3.4
0.39
0.35
u/ml
0.33
19
146
29
236
1.23
0.46
1.1
1.2
0.05
0.60
u/ml
—
8
82
728
7045
1.04
0.46
2.1
2.0
—
—
—
0
0
84
751
1.12
0.45
1.7
1.5
6.29
6.55
mmol/l
0.58
55
527
196
1828
1.08
0.45
1.4
1.3
219.59
232.41
miu/ml
0.20
98
938
10
69
1.45
0.44
1.0
1.2
—
—
—
0
0
45
386
1.17
0.43
1.5
2.1
133.72
130.70
g/l
0.61
36
297
9
128
0.70
0.43
1.2
1.1
—
—
—
0
0
178
1910
0.93
0.43
1.4
1.4
—
—
—
0
0
16
207
0.77
0.42
1.1
1.6
—
—
—
0
0
74
660
1.12
0.42
1.1
1.1
1.40
5.21
u/ml
1.84
27
249
5
32
1.56
0.42
1.6
1.5
0.28
0.45
ug/l
—
5
21
196
1834
1.07
0.42
1.1
1.0
—
—
—
0
0
33
391
0.84
0.41
1.3
1.6
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
638
6180
1.04
0.40
1.6
1.5
—
—
—
0
0
104
950
1.10
0.39
1.8
1.6
7.31
7.50
mmol/l
0.37
67
568
234
2209
1.06
0.39
2.9
3.1
32.92
32.77
%
0.08
178
1750
427
4102
1.05
0.39
1.5
1.5
—
—
—
0
0
60
532
1.13
0.38
1.1
1.1
0.05
0.42
u/ml
0.64
13
107
86
781
1.10
0.37
1.1
1.1
3.37
5.71
u/ml
1.02
39
399
33
387
0.85
0.37
1.3
1.6
—
—
—
0
0
36
419
0.86
0.37
2.8
2.0
1.93
1.57
ug/l
0.11
29
383
5
37
1.35
0.37
6.0
3.8
—
—
—
0
0
21
257
0.82
0.37
1.5
1.4
—
—
—
0
0
29
244
1.19
0.36
4.3
3.9
20.40
26.67
mg/l
0.67
23
204
147
1371
1.08
0.36
4.6
3.5
35.47
38.73
ug/l
0.03
107
964
11
81
1.36
0.36
1.1
1.1
—
—
—
0
0
11
81
1.36
0.36
1.1
1.1
93.91
95.54
%
0.07
11
81
54
479
1.13
0.35
1.6
1.5
11.54
10.14
mmol/l
—
7
31
9
122
0.74
0.35
1.3
1.6
—
—
—
0
0
336
3224
1.05
0.33
1.5
1.5
—
—
—
0
0
54
482
1.12
0.33
1.2
1.4
—
—
—
0
0
6
89
0.67
0.33
1.0
1.0
—
—
—
0
0
174
1641
1.06
0.32
1.3
1.5
—
—
—
0
0
69
626
1.10
0.32
1.1
1.1
—
—
—
0
0
80
732
1.10
0.32
1.1
1.1
0.87
1.35
u/ml
0.38
29
278
57
512
1.12
0.32
1.1
1.1
—
—
—
0
0
337
3240
1.05
0.31
1.5
1.5
—
—
—
0
0
7
97
0.72
0.30
1.1
1.8
—
—
—
0
0
7
97
0.72
0.30
1.1
1.8
—
—
—
0
0
7
97
0.72
0.30
1.1
1.8
—
—
—
0
0
7
97
0.72
0.30
1.1
1.8
—
—
—
0
0
39
343
1.14
0.30
1.5
2.8
23.98
24.23
mmol/l
0.18
32
304
16
196
0.82
0.30
1.4
2.1
—
—
—
0
0
64
582
1.10
0.29
1.1
1.0
1.75
3.99
u/ml
1.96
33
312
337
3247
1.04
0.29
1.5
1.5
—
—
—
0
0
178
1688
1.06
0.29
1.3
1.5
—
—
—
0
0
308
2969
1.04
0.27
2.0
2.3
2.41
2.41
mmol/l
0.54
268
2573
336
3245
1.04
0.27
1.5
1.5
—
—
—
0
0
46
510
0.90
0.26
1.9
2.3
24.39
24.59
mmol/l
0.29
40
474
10
77
1.30
0.26
1.1
1.1
64.74
73.45
ug/l
—
10
70
5
75
0.67
0.25
1.2
2.0
—
—
—
0
0
5
75
0.67
0.25
1.2
2.0
—
—
—
0
0
5
75
0.67
0.25
1.2
2.0
—
—
—
0
0
25
216
1.16
0.25
1.2
1.7
—
—
—
0
0
53
581
0.91
0.25
1.1
1.2
—
—
—
0
0
319
3084
1.04
0.25
2.6
2.5
343.98
275.07
ng/l
0.15
138
1400
90
841
1.07
0.24
2.3
1.8
95.36
94.54
%
0.11
83
751
6
82
0.73
0.24
1.2
1.3
—
—
—
0
0
207
1986
1.05
0.23
1.7
1.5
417.30
282.37
mu/l
0.43
181
1756
25
218
1.15
0.23
1.9
1.8
7.86
23.90
mg/l
—
7
64
17
143
1.19
0.23
1.4
1.6
—
—
—
0
0
20
231
0.86
0.22
1.1
1.1
1770.25
1485.30
miu/ml
0.63
20
231
30
267
1.12
0.21
1.1
1.1
1.08
1.04
ratio
0.50
13
96
0
10
0.00
0.21
0.0
1.1
—
26.15
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
81
759
1.07
0.21
1.9
1.9
—
—
—
0
0
148
1549
0.95
0.21
1.2
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
8
102
0.78
0.21
1.1
1.1
—
—
—
0
0
564
5756
0.98
0.20
3.4
3.3
1.02
1.02
kg/l
0.26
91
919
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
34
307
1.11
0.20
2.4
1.3
—
222.86
—
0
7
15
176
0.85
0.20
1.2
1.6
0.80
1.31
promille
—
10
126
15
127
1.18
0.19
1.1
1.1
—
—
—
0
0
33
364
0.91
0.19
1.1
1.2
—
—
—
0
0
25
222
1.13
0.19
2.1
1.5
—
—
—
0
0
66
618
1.07
0.18
1.1
1.2
3.59
3.54
mmol/l
0.17
61
581
7
61
1.15
0.17
2.7
2.3
—
—
—
0
0
13
110
1.18
0.17
1.3
1.6
121.31
122.31
nmol/l
0.03
13
110
7
63
1.11
0.17
1.0
2.2
—
—
—
0
0
11
92
1.20
0.16
1.5
1.3
5.67
6.45
mmol/l
1.08
11
86
8
73
1.10
0.15
1.0
1.0
—
—
—
0
0
9
78
1.15
0.15
1.8
1.6
—
—
—
0
0
20
224
0.89
0.15
1.1
1.7
—
—
—
0
0
64
677
0.94
0.15
1.9
2.0
—
—
—
0
0
11
129
0.85
0.14
1.2
1.3
—
—
—
0
0
621
6127
1.02
0.13
1.9
1.8
—
—
—
0
0
44
468
0.94
0.12
3.5
3.3
30.04
21.36
mg/l
0.65
28
285
45
423
1.06
0.12
1.4
1.3
1.22
1.31
nmol/l
0.20
32
361
898
9065
0.99
0.12
1.5
1.5
—
—
—
0
0
88
846
1.04
0.12
2.0
2.0
—
—
—
0
0
37
347
1.07
0.11
3.2
4.2
37.59
93.59
u/ml
—
8
114
20
219
0.91
0.11
1.0
1.1
0.97
1.01
u/l
—
9
87
64
612
1.05
0.11
1.2
1.4
1158.14
2277.39
e6/l
0.33
50
508
32
299
1.07
0.10
2.6
2.5
—
—
—
0
0
114
1175
0.97
0.10
11.7
7.2
122.16
121.92
g/l
0.05
108
1127
1349
13567
0.99
0.10
4.4
4.0
—
—
—
0
0
242
2376
1.02
0.09
1.6
1.5
—
—
—
0
0
99
1021
0.97
0.09
1.4
1.4
0.38
0.53
nmol/l
1.64
81
831
5
46
1.09
0.09
1.0
1.0
—
—
—
0
0
5
46
1.09
0.09
1.0
1.0
—
—
—
0
0
5
47
1.06
0.09
1.2
1.1
—
—
—
0
0
36
340
1.06
0.09
2.3
2.5
0.81
0.83
nmol/l
0.05
28
298
135
1384
0.97
0.09
10.4
6.7
0.28
0.74
mmol/l
0.76
104
1035
5
60
0.83
0.08
1.0
1.1
—
—
—
0
0
5
60
0.83
0.08
1.0
1.1
—
—
—
0
0
5
65
0.77
0.08
1.4
2.8
17.44
15.30
umol/l
—
5
65
7
65
1.08
0.08
1.0
1.3
—
—
—
0
0
7
65
1.08
0.08
1.0
1.3
—
—
—
0
0
23
246
0.93
0.08
2.0
1.9
—
—
—
0
0
7
67
1.04
0.08
1.9
1.5
—
—
—
0
0
7
67
1.04
0.08
1.1
1.5
7.97
7.55
ug/l
—
7
67
199
1956
1.02
0.08
1.5
1.5
—
—
—
0
0
201
1976
1.02
0.07
2.7
2.3
24.31
30.77
u/ml
0.82
196
1913
6
72
0.83
0.07
1.2
3.6
—
—
—
0
0
78
757
1.03
0.07
1.2
1.1
—
—
—
0
0
8
75
1.07
0.07
1.0
6.7
—
59.85
—
0
13
7
81
0.86
0.07
1.0
1.1
—
—
—
0
0
347
3431
1.01
0.07
1.6
1.5
—
—
—
0
0
11
122
0.90
0.07
1.2
1.8
106.73
105.97
mmol/l
0.66
11
122
11
122
0.90
0.07
1.2
1.8
4.00
3.93
mmol/l
0.30
11
122
23
216
1.07
0.06
1.6
1.7
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
12
132
0.91
0.06
1.3
1.1
—
—
—
0
0
20
187
1.07
0.06
1.2
1.3
—
62.30
—
0
10
63
612
1.03
0.06
1.2
1.3
3.14
22.61
e6/l
3.61
44
478
353
3498
1.01
0.05
1.5
1.6
—
—
—
0
0
33
317
1.04
0.05
1.2
1.1
—
—
—
0
0
20
189
1.06
0.04
1.4
1.5
—
—
—
0
0
77
754
1.02
0.04
1.2
1.1
—
—
—
0
0
81
794
1.02
0.04
1.7
2.5
1.03
1.26
mmol/l
0.34
49
556
471
4682
1.01
0.04
1.7
1.8
—
—
—
0
0
15
160
0.94
0.04
1.3
1.4
1456.67
405.97
mu/l
0.40
15
153
29
301
0.96
0.03
1.0
1.1
—
—
—
0
0
14
149
0.94
0.03
1.1
1.0
—
—
—
0
0
24
250
0.96
0.03
1.4
1.7
—
—
—
0
0
104
1027
1.01
0.03
1.4
1.4
25.84
23.76
u/l
0.26
84
854
123
1217
1.01
0.02
10.9
7.0
96.23
96.58
%
0.18
117
1172
71
699
1.02
0.02
1.1
1.3
419.97
453.06
mg/l
0.28
65
668
15
142
1.06
0.02
1.5
2.1
30.20
32.18
pg
0.59
15
142
137
1382
0.99
0.02
10.3
6.7
5.00
4.98
kpa
0.13
132
1329
137
1382
0.99
0.02
10.3
6.7
14.35
13.96
kpa
0.29
132
1327
15
157
0.96
0.01
1.7
1.8
1.17
2.27
u/field
—
6
80
45
443
1.02
0.01
1.1
1.3
—
—
—
0
0
10
94
1.06
0.01
1.0
1.1
—
—
—
0
0
32
314
1.02
0.00
1.0
1.1
167.83
197.69
mg/l
1.41
26
278
14
145
0.97
0.00
1.9
3.8
—
—
—
0
0
32
325
0.98
0.00
1.1
1.2
46.60
34.88
mg/l
0.33
23
271
113
1131
1.00
0.00
1.5
1.5
—
—
—
0
0
11
112
0.98
0.00
1.1
1.5
11.56
13.63
pmol/l
1.06
11
94
21
208
1.01
0.00
1.8
1.6
—
—
—
0
0
33
328
1.01
0.00
1.1
1.2
—
—
—
0
0
98
977
1.00
0.00
1.9
2.3
0.35
0.20
e6/l
0.53
92
921
18
183
0.98
0.00
1.5
1.3
—
—
—
0
0
17
167
1.02
0.00
1.3
1.4
74.14
72.96
%
0.14
17
160
5
50
1.00
0.00
1.0
1.1
—
—
—
0
0
5
50
1.00
0.00
1.2
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
2.2
—
—
—
0
0
7
78
0.90
0.00
1.1
1.1
—
—
—
0
0
5
49
1.02
0.00
1.0
1.4
—
—
—
0
0
8
86
0.93
0.00
8.1
13.7
1197.88
1274.30
nmol/l
—
8
80
83
830
1.00
0.00
1.7
2.6
4.99
5.08
kpa
0.54
73
775
6
65
0.92
0.00
1.0
1.1
—
—
—
0
0
7
79
0.89
0.00
1.9
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
4.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
8
82
0.98
0.00
1.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
4.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
9
94
0.96
0.00
3.6
2.4
1.69
1.61
nmol/l
—
9
83
8
80
1.00
0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
5.2
—
—
—
0
0
6
66
0.91
0.00
1.0
1.0
—
—
—
0
0
7
69
1.01
0.00
1.9
1.5
—
—
—
0
0
8
83
0.96
0.00
3.5
3.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
87.60
—
0
5
5
58
0.86
0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
1.14
—
0
5
5
52
0.96
0.00
1.6
1.5
12.54
68.60
u/l
—
5
46
8
80
1.00
0.00
1.1
1.1
—
—
—
0
0
8
85
0.94
0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint O15_ICP_EXMORE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| O15_ICP_EXMORE | 0.646 [0.5, 0.83] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.437 |
During the follow-up period (1.1.1998 — 31.12.2019), 78 out of 13331 females with O15_ICP_EXMORE died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have O15_ICP_EXMORE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.056% | No data |
| 5 | 0.38% | No data |
| 10 | 1.081% | No data |
| 15 | 1.972% | No data |
| 20 | 3.48% | No data |
Relationships between endpoints
↥Index endpoint: O15_ICP_EXMORE – Intrahepatic Cholestasis of Pregnancy (ICP) , excluding more controls
GWS hits: 33
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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