No definition available.
Intrahepatic Cholestasis of Pregnancy (ICP) , excluding more controls
O15_ICP_EXMORE
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleonly females |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
- Control exclude
- !(O15_DELIVERY, O15_DELIVERY_PROXY)
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF3
- Parent code in ICD-10
- O26
- Name in latin
- Morbositates hepatis in graviditate, intra labores et/sive in puerperio
Similar endpoints
↥List of similar endpoints to
Intrahepatic Cholestasis of Pregnancy (ICP) , excluding more controls
based on the number of shared cases.
Similar with more cases:
- Intrahepatic Cholestasis of Pregnancy (ICP)
- Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8
- Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8, excluding more controls
- Pregnancy, childbirth and the puerperium
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 19565 | 19565 | - |
| Only index persons | 19357 | 19357 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.56 | 0.56 | - |
| Only index persons | 0.71 | 0.71 | - |
| Median age at first event (years) | |||
| Whole population | - | 29.97 | - |
| Only index persons | - | 29.97 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2935 | 2935 | - |
| Unadjusted period prevalence (%) | 1.04 | 1.04 | - |
| Median age at first event (years) | 30.46 | 30.46 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 3058
- Matched controls
- 30580
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
6467A
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Liver disorders in pregnancy[HEPATOSIS GRAVIDARUM]
+∞
307.7
733
*
A05AA02
ATC
ursodeoxycholic acid; oral
123.3
307.7
1022
124
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
14638.1
307.7
2407
9
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.2
94.3
418
1437
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
2.4
64.4
492
2223
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.4
61.3
487
2236
O80.8
ICD-10 Finland
Other single spontaneous delivery
2.0
38.4
458
2443
63900
ICD-8 Finland
Other toxaemias of pregnancy and the puerperium, Pruritus
13.0
37.5
36
28
O30.0
ICD-10 Finland
Twin pregnancy
2.9
33.7
164
586
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
2.4
33.4
253
1125
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.7
28.8
742
4961
W84
ICPC
Pregnancy high risk
2.0
28.6
353
1896
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
1.6
26.7
745
5066
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
2.4
26.2
189
821
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
3.3
25.4
95
291
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
3.5
24.9
88
260
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
1.5
24.1
1305
10213
L29.9
ICD-10 Finland
Pruritus, unspecified
2.8
23.9
118
425
MAC96
NOMESCO Finland
Other induction or advancement of labour
2.1
20.8
215
1081
S02
ICPC
Pruritus
2.4
19.5
130
545
O60
ICD-10 Finland
Preterm labour and delivery
2.0
19.2
209
1071
K76.9
ICD-10 Finland
Liver disease, unspecified
3.8
18.8
56
148
5742A
ICD-9 Finland
Cholelithiasis, Calculus of gallbladder without mention of cholecystitis[CHOLECYSTOLITHIASIS SINE CHOLECYSTITIDE,SINE OBSTR]
3.8
18.5
55
145
63998
ICD-8 Finland
Other toxaemias of pregnancy and the puerperium, Alia definitae
18.7
17.3
26
14
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
1.5
16.4
662
4813
A10BX01
ATC
guar gum; oral
3.4
15.8
55
162
8811
FHL
Cesarean section
1.8
15.5
260
1531
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
1.6
15.3
433
2914
O98.4
ICD-10 Finland
Viral hepatitis complicating pregnancy, childbirth and the puerperium
7.0
15.3
23
33
XMA22
NOMESCO Finland
General examination of pregnant woman
1.5
14.6
442
3019
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
1.7
14.6
251
1488
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
0.6
14.0
200
3389
6467X
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Liver disorders in pregnancy[HEPATOPATHIA ALIA GRAVIDARUM]
+∞
13.5
13
*
K83.0
ICD-10 Finland
Cholangitis
4.4
13.1
32
73
MAA00
NOMESCO Finland
Amniocentesis
1.9
12.6
164
893
6510B
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, SYNNYTYKSEN AIKANA]
3.4
12.6
44
130
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
3.7
12.4
38
103
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
12.2
314
2064
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
4.2
12.0
31
74
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
1.4
11.9
674
5177
B18.2
ICD-10 Finland
Chronic viral hepatitis C
3.4
11.8
42
126
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
2.9
11.7
54
189
L29.8
ICD-10 Finland
Other pruritus
3.1
11.5
46
148
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
1.8
11.2
166
942
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
1.6
11.0
265
1714
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
1.3
10.9
1143
9593
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
10.7
1228
10423
V230A
ICD-9 Finland
Supervision of high-risk pregnancy, Pregnancy with history of infertility
2.7
10.6
55
205
6510A
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, RASKAUDEN AIKANA]
3.8
10.0
30
80
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
2.3
10.0
74
327
O26.0
ICD-10 Finland
Excessive weight gain in pregnancy
4.8
10.0
22
46
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
1.5
9.7
318
2201
ZXE00
NOMESCO Finland
One hour or less
1.3
9.7
1168
9936
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
1.7
9.5
156
915
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
8.0
9.3
20
25
O48
ICD-10 Finland
Prolonged pregnancy
0.5
9.3
96
1797
G03DA04
ATC
progesterone; systemic, rectal, vaginal
1.8
9.1
141
813
6663
FHL
Cholecystectomy and cholangiography
3.4
9.0
31
91
L04AX01
ATC
azathioprine; systemic
1.9
8.9
112
606
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
1.3
8.1
724
5901
O84.2
ICD-10 Finland
Multiple delivery, all by caesarean section
2.8
8.1
40
146
Z2221
NOMESCO Finland
Medical doctor
1.3
8.1
800
6606
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.3
8.0
531
4154
6488A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Abnormal glucose tolerance
2.2
7.9
64
295
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
1.9
7.9
102
558
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
4.1
7.8
21
52
A10AC01
ATC
insulin (human); parenteral
1.6
7.7
169
1072
6480A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Diabetes mellitus
3.1
7.6
31
102
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
3.1
7.4
30
98
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
3.1
7.4
30
98
O26.9
ICD-10 Finland
Pregnancy-related condition, unspecified
2.4
7.2
48
204
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
2.0
7.2
73
368
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
1.7
7.1
115
673
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
2.1
7.1
62
296
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
8.8
7.0
14
16
K80.1
ICD-10 Finland
Calculus of gallbladder with other cholecystitis
2.2
7.0
53
238
A02BC01
ATC
omeprazole; systemic
1.3
7.0
670
5503
K30
ICD-10 Finland
Functional dyspepsia
1.4
6.9
314
2314
O82.0
ICD-10 Finland
Delivery by elective caesarean section
1.4
6.8
305
2240
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
2.2
6.5
54
252
G03GB02
ATC
clomifene; oral
1.7
6.5
104
607
K50.9
ICD-10 Finland
Crohn disease, unspecified
2.3
6.5
46
201
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
1.9
6.5
74
390
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
1.9
6.4
80
433
O99.80
ICD-10 Finland
The fear of childbirth
1.4
6.4
368
2813
B01AB04
ATC
dalteparin; parenteral
1.7
6.4
120
732
ZXD05
NOMESCO Finland
Urgent procedure
1.2
6.4
987
8541
ZXD10
NOMESCO Finland
Scheduled procedure
1.2
6.3
910
7816
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
1.3
6.3
448
3533
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
1.6
6.3
122
752
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
1.7
6.2
107
640
1413
FHL
Laparoscopy and other therapeutic procedure
1.9
6.1
69
362
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
1.6
6.0
134
854
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.4
6.0
227
1618
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
5.2
6.0
17
33
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
865
1255
9.22
307.65
6.1
1.5
10.14
3.88
umol/l
23.59
766
882
298
521
6.23
165.12
1.2
1.3
107.84
108.18
u/ml
0.02
57
145
306
568
5.88
159.24
1.2
1.3
14.08
16.52
u/ml
—
5
18
297
538
6.01
158.54
1.2
1.2
197.04
268.85
u/ml
6.10
243
358
308
579
5.80
158.11
1.2
1.2
—
—
—
0
0
114
146
8.07
83.63
1.1
1.2
—
—
—
0
0
1467
11098
1.62
36.29
5.0
4.9
9.70
9.31
umol/l
0.80
1376
10468
451
2485
1.96
34.24
2.4
2.4
6.01
5.68
umol/l
0.15
400
2103
1143
8383
1.58
30.59
3.5
2.8
34.13
27.73
u/l
4.90
1094
8043
170
672
2.62
28.81
1.5
1.2
74.29
200.46
titre
0.82
14
65
2916
27364
2.41
24.14
10.8
7.9
32.65
23.62
u/l
38.65
2872
26698
2032
17404
1.50
23.53
7.3
6.2
78.75
70.63
u/l
14.84
1933
16524
254
1378
1.92
19.77
1.7
1.8
1.37
1.37
g/l
0.01
235
1294
315
1832
1.80
19.68
2.3
2.5
10.70
10.36
g/l
1.05
289
1700
265
1492
1.85
18.37
2.3
2.1
0.22
0.23
g/l
0.81
247
1410
1333
11213
1.33
13.29
8.1
7.4
0.00
0.00
e9/l
0.52
1118
9334
894
7130
1.36
12.54
2.4
2.3
59.49
56.26
u/l
0.34
846
6707
1009
8223
1.34
12.20
4.4
4.0
36.63
37.02
g/l
1.59
948
7743
683
5272
1.38
11.63
3.8
2.9
99.67
99.91
%
0.10
658
5083
265
1730
1.58
10.61
3.1
4.0
220.71
235.75
u/l
1.06
251
1639
1288
11016
1.29
10.54
6.1
5.3
0.74
0.68
%
4.07
1232
10300
1346
11578
1.29
10.54
6.2
5.5
7.85
7.72
%
1.00
1292
10935
1337
11505
1.29
10.38
6.0
5.3
2.83
2.81
%
0.19
1281
10829
2066
18826
1.30
10.09
3.2
2.6
38.47
32.00
u/l
4.02
1970
18132
45
155
2.93
10.07
1.3
1.3
309.09
165.26
titre
0.43
11
38
45
159
2.86
9.64
1.1
1.1
—
—
—
0
0
1388
12086
1.27
9.51
6.0
5.2
30.13
30.00
%
0.19
1332
11456
910
7515
1.30
9.49
5.1
5.3
1.03
1.04
inr
0.64
344
2647
765
6175
1.32
9.42
1.5
1.4
2.09
2.09
g/l
0.02
495
4054
49
185
2.68
9.28
1.1
1.1
317.48
291.81
mg/l
0.85
42
171
1365
11926
1.26
8.87
5.8
5.1
56.03
56.27
%
0.40
1313
11286
65
295
2.23
8.33
1.1
1.1
1.41
1.43
g/l
0.10
57
268
48
191
2.54
8.23
1.0
1.1
—
—
—
0
0
1441
12792
1.24
7.74
6.0
5.2
1.93
1.97
e9/l
1.09
1335
11711
279
1979
1.45
7.54
2.4
2.1
35.49
35.45
u/l
0.00
249
1696
1444
12845
1.24
7.53
6.1
5.3
0.18
0.18
e9/l
0.16
1333
11635
411
3120
1.37
7.51
1.9
2.1
14.91
14.88
umol/l
0.03
386
2932
331
2429
1.41
7.42
1.9
2.1
24.29
24.49
%
0.09
286
2089
2527
23977
1.31
7.25
12.5
11.0
15.75
14.37
%
0.41
2502
23623
1704
15477
1.23
7.11
3.2
3.0
56.33
63.47
ug/l
3.69
1627
14774
697
5753
1.27
6.95
2.2
2.0
2.50
2.61
mg/l
0.84
615
5021
689
5693
1.27
6.79
2.6
2.5
0.16
0.26
e6/l
2.68
516
4207
104
601
1.76
6.74
2.3
2.0
1.11
1.25
g/l
0.82
88
526
366
2777
1.36
6.70
1.9
2.0
2.52
2.51
g/l
0.11
337
2570
1178
10346
1.23
6.68
2.4
2.2
74.90
74.35
nmol/l
0.30
1115
9795
757
6343
1.26
6.61
2.7
2.6
34.57
78.89
e6/l
1.12
563
4734
2023
18794
1.23
6.42
4.1
3.6
9.53
8.94
mm/h
1.74
1925
17846
1551
14050
1.21
6.31
7.7
7.3
3.83
3.91
e9/l
0.94
1391
12442
167
1111
1.53
6.22
1.3
1.4
—
—
—
0
0
33
134
2.48
5.53
3.0
3.0
8.75
7.37
mg/l
0.49
26
99
75
423
1.79
5.35
4.3
3.4
1051.13
432.04
u/ml
0.34
66
362
874
7583
1.21
5.33
1.3
1.3
1.05
1.49
u/ml
1.35
263
2372
2460
23502
1.24
5.14
8.5
7.5
94.23
93.82
ml/min/173m2
0.54
2068
19283
2531
24266
1.25
5.06
4.2
4.0
—
—
—
0
0
54
280
1.95
5.02
1.3
1.3
—
—
—
0
0
536
4447
1.25
4.97
2.3
2.2
9.53
8.63
e6/l
0.21
475
3920
653
5568
1.22
4.67
1.3
1.3
10.11
8.73
u/ml
0.26
261
2473
644
5504
1.22
4.48
2.2
2.0
669.56
1855.83
umol/l
1.89
584
5051
2617
25281
1.24
4.29
5.2
5.0
1.64
1.86
mu/l
1.29
2498
24242
324
2577
1.29
4.27
2.2
1.9
29.02
28.77
s
0.34
307
2475
493
4124
1.23
4.22
3.1
2.4
104.31
93.02
ug/g
0.37
395
3259
903
8013
1.18
4.11
4.5
4.4
1.22
1.22
mmol/l
0.53
858
7446
2360
22593
1.20
4.10
4.6
4.4
14.25
14.21
pmol/l
0.41
2222
21533
667
5772
1.20
4.04
1.3
1.3
24.65
24.54
iu/ml
0.01
216
1946
1020
9167
1.17
3.94
4.8
5.0
1.22
1.22
mmol/l
0.28
870
7815
137
971
1.43
3.84
2.0
2.0
40.46
38.61
u/l
0.55
126
908
88
578
1.54
3.61
2.7
1.7
696.00
308.00
titre
—
5
30
2579
24982
1.21
3.49
9.0
8.3
3.88
3.89
mmol/l
1.03
2518
24298
235
1843
1.30
3.48
2.4
2.4
—
—
—
0
0
830
7402
1.17
3.46
1.7
1.7
100.81
100.31
pmol/l
0.11
441
4152
119
840
1.43
3.45
2.5
2.2
3.91
3.65
g/l
1.12
107
784
46
261
1.77
3.35
1.1
1.2
—
—
—
0
0
42
232
1.82
3.33
1.2
1.1
—
55.04
—
0
5
2569
24900
1.20
3.32
8.9
8.3
139.60
139.58
mmol/l
0.24
2509
24303
2188
20941
1.16
3.29
4.0
3.8
36.89
36.95
mmol/mol
0.13
2082
19974
34
178
1.92
3.19
1.4
1.5
—
—
—
0
0
491
4222
1.19
3.16
3.9
3.7
12.20
11.35
mg/mmol
0.16
316
2692
362
3027
1.22
3.12
2.2
2.3
5.33
4.90
e6/l
0.17
185
1583
585
5113
1.18
3.11
3.6
3.1
7.60
7.67
mmol/l
0.14
523
4579
611
5371
1.17
3.03
1.9
1.9
113.59
135.81
u/l
0.83
588
5129
694
6163
1.16
3.02
1.9
1.7
0.94
0.83
mg/l
0.60
514
4564
139
1037
1.36
2.96
6.2
6.6
6.70
6.59
mmol/l
0.09
131
1005
274
2239
1.25
2.94
1.3
1.3
208.92
148.46
u/ml
0.32
263
2093
382
3233
1.21
2.92
2.2
2.2
2.27
1.01
e6/l
0.48
204
1783
471
4065
1.19
2.90
3.4
3.2
494.63
535.62
mg/l
0.06
303
2571
166
2128
0.77
2.81
4.1
4.2
—
—
—
0
0
287
2380
1.23
2.70
2.9
3.5
4.58
4.58
pmol/l
0.02
265
2163
318
2666
1.22
2.69
2.9
3.0
0.83
0.83
mmol/l
0.19
303
2540
35
197
1.79
2.67
1.7
2.5
62.72
61.99
%
0.06
35
197
43
257
1.68
2.67
1.2
1.1
—
—
—
0
0
741
6667
1.15
2.67
2.6
2.8
2.34
2.34
mmol/l
0.01
677
6144
23
112
2.06
2.67
2.0
1.5
1.76
5.86
u/l
2.75
17
95
449
3889
1.18
2.66
1.4
1.4
20.96
21.21
nmol/l
0.15
403
3494
75
514
1.47
2.61
3.8
3.6
56.99
57.05
%
0.02
75
514
14
55
2.55
2.61
1.3
3.0
13180.67
63.72
mg/l
—
9
40
620
5517
1.16
2.60
1.5
1.6
1.22
1.33
mmol/l
1.80
549
4849
177
1401
1.28
2.52
1.2
1.3
0.27
0.92
u/ml
1.69
12
111
149
1157
1.30
2.46
1.7
1.7
—
—
—
0
0
132
1008
1.32
2.46
1.4
1.4
—
—
—
0
0
1949
18660
1.12
2.45
4.3
3.8
764.68
1158.83
e6/l
0.21
19
190
112
835
1.35
2.45
1.2
1.3
6.92
7.34
u/ml
0.04
14
142
1414
13306
1.12
2.40
4.0
3.6
6.10
6.13
mmol/l
0.22
1259
11653
110
823
1.35
2.36
1.2
1.3
7.40
6.24
u/ml
—
9
79
105
780
1.36
2.36
1.2
1.2
64.44
39.37
u/ml
—
7
73
389
3368
1.18
2.33
1.6
1.6
1.34
1.30
%
0.41
340
3024
38
229
1.67
2.33
1.0
1.1
8.69
9.97
iu/ml
—
10
59
30
169
1.78
2.32
2.2
1.4
—
—
—
0
0
337
2887
1.19
2.29
2.3
2.2
308.26
376.91
ng/l
0.44
266
2302
960
8870
1.12
2.22
1.7
1.7
—
—
—
0
0
2718
26659
1.18
2.12
10.5
9.4
16.03
17.72
mg/l
2.50
2123
20705
186
1517
1.24
2.10
3.1
3.0
1.22
1.23
mmol/l
1.80
170
1318
78
565
1.39
2.08
1.2
1.1
12.11
11.61
au/ml
0.03
12
36
475
4224
1.15
2.02
1.6
1.5
18868355.46
45082831.01
pmol/l
0.66
424
3762
185
2241
0.81
1.99
1.4
1.5
—
—
—
0
0
1466
13931
1.10
1.91
3.3
3.1
0.00
0.00
estimate
0.88
384
3046
127
1003
1.28
1.91
1.9
2.0
—
—
—
0
0
289
2489
1.18
1.88
1.9
2.1
370.17
372.19
nmol/l
0.07
269
2329
19
100
1.91
1.85
1.1
1.2
—
—
—
0
0
24
137
1.76
1.83
3.5
2.7
41205.00
39342.93
ug/l
0.26
24
137
167
1370
1.23
1.82
2.1
2.6
1.59
1.68
%
0.53
146
1237
119
941
1.28
1.79
1.3
1.3
85.86
28.89
u/ml
—
5
71
21
116
1.82
1.78
1.9
1.6
1.83
1.94
umol/l
0.35
21
110
141
1140
1.25
1.76
9.2
5.5
1.26
1.23
mmol/l
0.16
141
1112
1477
14078
1.10
1.75
3.3
3.2
0.00
0.00
estimate
1.32
383
2956
126
1007
1.26
1.74
1.8
2.2
3.22
4.29
iu/l
1.75
47
429
230
1957
1.19
1.74
4.1
4.6
1.06
1.04
mmol/l
0.50
219
1841
1467
13986
1.09
1.72
4.4
4.3
0.00
0.00
estimate
0.80
382
3006
8
30
2.67
1.72
1.3
1.2
—
—
—
0
0
5
13
3.85
1.71
1.0
1.2
—
—
—
0
0
408
3636
1.14
1.70
2.7
2.3
6781.95
7013.52
u/l
0.05
183
1699
98
766
1.29
1.64
1.3
1.4
—
—
—
0
0
24
143
1.68
1.61
1.2
1.2
—
—
—
0
0
120
1482
0.80
1.60
2.1
2.2
—
—
—
0
0
25
151
1.66
1.59
1.2
1.1
95.40
100.33
%
—
10
61
103
1294
0.79
1.59
1.3
1.2
11.02
11.53
u/l
0.16
88
1106
8
32
2.50
1.59
1.0
1.2
—
—
—
0
0
45
312
1.45
1.59
1.2
1.2
—
—
—
0
0
45
312
1.45
1.59
1.2
1.2
—
—
—
0
0
152
1258
1.22
1.56
1.5
1.6
—
—
—
0
0
87
676
1.30
1.54
1.2
1.3
—
—
—
0
0
2423
23702
1.11
1.52
3.3
3.2
5.52
5.52
mmol/l
0.04
2280
22499
23
138
1.67
1.51
1.7
1.7
2.38
2.64
mg/l
0.35
23
132
368
3297
1.13
1.44
1.7
1.5
—
—
—
0
0
66
499
1.33
1.43
1.4
1.5
—
—
—
0
0
21
125
1.68
1.43
1.1
1.1
—
—
—
0
0
36
245
1.47
1.42
1.3
1.1
—
—
—
0
0
114
927
1.24
1.41
1.6
1.5
—
—
—
0
0
103
829
1.25
1.40
1.8
2.1
54.91
68.59
ng/l
0.62
87
736
36
246
1.47
1.40
1.3
1.1
—
—
—
0
0
111
902
1.24
1.39
1.2
1.2
—
—
—
0
0
25
158
1.59
1.37
1.2
1.3
—
—
—
0
0
71
550
1.30
1.32
1.4
1.3
326.49
331.78
ug/g
0.08
33
259
101
1240
0.81
1.32
1.3
1.3
3.02
3.97
ug/l
1.50
94
1159
36
250
1.45
1.30
1.3
1.1
—
—
—
0
0
36
250
1.45
1.30
1.3
1.1
—
—
—
0
0
36
250
1.45
1.30
1.3
1.1
—
—
—
0
0
29
193
1.51
1.29
1.1
1.3
1.55
1.57
g/l
0.23
29
193
122
1011
1.22
1.29
2.3
2.2
67.20
67.53
g/l
0.23
114
947
37
260
1.43
1.27
2.4
2.8
9.49
127.14
ug/min
3.41
28
174
53
398
1.34
1.24
1.4
1.4
—
—
—
0
0
23
147
1.57
1.23
1.2
1.1
99.80
103.18
%
—
10
60
106
871
1.22
1.23
1.9
2.6
4.87
4.65
kpa
0.35
101
839
8
37
2.17
1.21
1.0
1.7
—
—
—
0
0
8
37
2.17
1.21
1.0
1.7
—
—
—
0
0
710
6652
1.09
1.19
2.3
2.3
21.19
22.21
ng/l
0.06
242
2438
109
902
1.22
1.18
2.2
2.0
0.22
0.23
g/l
0.14
104
853
800
7535
1.08
1.18
3.4
3.4
0.01
0.00
estimate
0.49
380
2962
35
248
1.42
1.16
1.2
1.2
—
—
—
0
0
245
2173
1.14
1.16
1.9
1.8
—
—
—
0
0
34
241
1.42
1.13
1.4
1.3
—
—
—
0
0
127
1072
1.19
1.13
1.1
1.1
7.72
5.56
u/ml
0.12
19
178
35
250
1.40
1.12
1.2
1.2
—
—
—
0
0
19
119
1.60
1.11
1.3
1.3
—
—
—
0
0
299
2701
1.12
1.06
1.7
1.6
1147.56
1206.18
nmol/l
0.58
240
2212
221
1960
1.14
1.06
1.3
1.3
23.13
38.12
au/ml
—
6
102
75
605
1.25
1.06
2.1
2.1
10.24
9.88
mg/l
0.15
70
574
348
3172
1.11
1.05
1.3
1.2
167.27
157.47
iu/ml
0.17
140
1322
104
869
1.20
1.05
1.5
1.6
0.01
21.61
iu/ml
0.51
14
156
3002
29870
1.27
1.02
16.2
14.1
266.64
267.41
e9/l
0.29
2960
29437
43
324
1.33
1.02
1.1
1.5
—
2933.33
—
0
6
13
76
1.71
0.98
33.8
24.7
118.08
116.94
ug/l
0.02
13
63
2512
24747
1.08
0.97
3.4
3.3
4.78
4.87
mmol/l
5.62
2422
23843
0
30
0.00
0.97
0.0
1.1
—
—
—
0
0
44
570
0.77
0.96
1.4
1.4
33.85
31.05
nmol/l
0.24
37
516
17
108
1.58
0.96
1.4
1.8
—
—
—
0
0
0
31
0.00
0.96
0.0
1.1
—
—
—
0
0
12
69
1.74
0.96
1.1
1.1
—
—
—
0
0
236
2119
1.12
0.95
2.3
2.3
18.19
23.25
au/ml
0.50
13
228
51
399
1.28
0.95
1.1
1.2
—
—
—
0
0
167
1472
1.14
0.91
1.8
1.6
3.12
4.22
mg/l
1.18
126
1028
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
28
201
1.40
0.91
1.9
1.5
124.72
118.83
%
0.18
28
191
62
500
1.24
0.91
1.2
1.1
—
—
—
0
0
35
263
1.33
0.87
1.3
1.5
—
—
—
0
0
2996
29821
1.23
0.87
16.2
14.0
39.61
39.97
%
0.86
2888
28619
10
168
0.59
0.86
1.8
1.4
20.20
25.42
umol/l
—
10
159
25
178
1.41
0.86
1.1
1.1
—
—
—
0
0
35
264
1.33
0.86
1.3
1.5
—
—
—
0
0
89
751
1.19
0.85
1.1
1.1
0.95
1.66
u/ml
0.62
41
345
40
308
1.30
0.85
1.8
1.9
17.54
17.01
%
0.32
16
151
1146
11044
1.06
0.85
3.3
3.1
—
—
—
0
0
21
298
0.70
0.85
1.3
1.6
—
—
—
0
0
21
298
0.70
0.85
1.3
1.6
—
—
—
0
0
51
406
1.26
0.85
2.2
2.0
5.47
5.40
mmol/24h
0.06
46
369
384
3561
1.09
0.85
1.6
1.5
—
—
—
0
0
35
265
1.32
0.84
1.3
1.5
—
—
—
0
0
3002
29892
1.23
0.82
16.2
14.1
6.68
6.76
e9/l
1.19
2962
29412
11
65
1.69
0.82
1.3
1.1
—
—
—
0
0
63
517
1.22
0.81
1.3
1.2
2.13
4.80
u/ml
2.63
24
197
49
392
1.25
0.79
3.0
1.9
115.47
231.21
ug/l
1.39
39
337
299
2753
1.10
0.78
1.6
1.7
—
—
—
0
0
3002
29897
1.22
0.78
16.2
14.1
4.45
4.45
e12/l
0.12
2964
29451
35
269
1.30
0.77
1.3
1.5
—
—
—
0
0
13
198
0.66
0.76
1.4
1.5
—
—
—
0
0
13
198
0.66
0.76
1.4
1.5
—
—
—
0
0
328
3038
1.09
0.76
1.9
1.8
—
—
—
0
0
16
107
1.50
0.76
1.6
1.4
—
—
—
0
0
35
270
1.30
0.76
1.3
1.5
—
—
—
0
0
2522
24912
1.07
0.75
3.5
3.5
2.88
2.94
mmol/l
3.61
2419
23875
5
24
2.09
0.74
1.0
1.1
—
—
—
0
0
17
116
1.47
0.74
1.1
1.1
—
—
—
0
0
75
636
1.18
0.71
1.1
1.1
1.02
4.99
u/ml
6.33
31
249
130
1151
1.14
0.71
2.7
3.0
72.31
70.97
ng/l
0.08
120
1036
2396
23642
1.06
0.70
3.0
3.0
1.09
1.16
mmol/l
8.54
2309
22693
9
143
0.63
0.69
1.9
2.1
—
—
—
0
0
103
899
1.15
0.69
1.1
1.1
2.38
2.29
u/ml
0.03
52
420
65
546
1.19
0.69
1.3
1.2
1.33
2.81
u/ml
1.94
21
185
122
1079
1.14
0.68
2.6
3.1
1.34
1.74
mmol/l
0.56
96
904
9
59
1.53
0.68
1.9
1.3
—
—
iu/ml
—
0
0
35
275
1.28
0.68
1.3
1.5
—
—
—
0
0
50
606
0.82
0.68
1.2
1.2
—
—
—
0
0
3002
29909
1.20
0.68
16.3
14.2
132.21
132.98
g/l
4.01
2987
29725
44
356
1.24
0.67
1.9
1.6
14157.81
7151.81
e6/l
0.34
31
262
244
2246
1.09
0.67
2.9
3.1
33.22
32.79
%
0.26
185
1807
5
94
0.53
0.66
4.4
2.7
—
—
—
0
0
42
339
1.24
0.66
1.1
1.1
93.98
93.07
%
0.09
42
314
52
430
1.21
0.66
2.6
1.9
—
—
—
0
0
12
178
0.67
0.64
1.2
1.7
—
—
—
0
0
14
201
0.70
0.64
1.1
1.1
—
—
—
0
0
26
198
1.32
0.64
1.7
1.6
48.59
46.23
%
0.10
17
111
2493
24654
1.06
0.62
3.3
3.2
1.55
1.55
mmol/l
0.20
2404
23719
154
1702
0.90
0.62
2.0
2.1
76.81
79.85
ml/min/173m2
0.48
53
600
23
302
0.76
0.62
1.7
1.4
—
—
—
0
0
706
6781
1.05
0.59
1.6
1.5
—
—
—
0
0
183
1997
0.91
0.59
1.4
1.4
—
—
—
0
0
28
219
1.28
0.58
2.6
2.9
—
—
—
0
0
71
819
0.86
0.57
4.7
7.2
24.24
24.18
mmol/l
0.06
64
778
87
764
1.14
0.57
1.7
1.5
6.24
6.53
mmol/l
0.81
74
703
36
441
0.81
0.57
1.1
1.1
2.33
21091.51
iu/ml
—
6
127
6
36
1.67
0.56
1.0
1.4
—
—
—
0
0
16
115
1.39
0.56
1.1
1.3
68.45
90.49
nmol/24h
0.93
16
115
30
239
1.26
0.55
1.1
1.2
0.28
0.92
u/ml
0.99
14
115
32
257
1.25
0.55
1.2
1.2
—
—
—
0
0
6
38
1.58
0.54
5.3
3.7
—
—
—
0
0
60
515
1.17
0.54
3.6
5.1
1.71
1.81
%
0.15
54
476
47
395
1.19
0.53
1.9
1.7
—
—
—
0
0
111
998
1.12
0.52
1.8
1.6
7.59
7.55
mmol/l
0.07
103
961
10
146
0.68
0.52
1.1
1.7
—
—
—
0
0
10
146
0.68
0.52
1.1
1.7
—
—
—
0
0
10
146
0.68
0.52
1.1
1.7
—
—
—
0
0
9
134
0.67
0.51
1.2
1.1
—
—
—
0
0
20
153
1.31
0.50
2.1
1.5
44.28
45.19
%
0.03
15
82
17
224
0.76
0.49
1.6
1.4
—
—
—
0
0
14
101
1.39
0.49
1.1
1.5
—
—
u/ml
—
0
0
28
345
0.81
0.49
1.0
1.1
—
—
—
0
0
82
922
0.89
0.48
1.6
1.8
11.11
4.58
ug/l
0.86
75
813
57
493
1.16
0.48
1.2
1.4
—
—
—
0
0
119
1080
1.11
0.48
1.6
1.5
—
—
—
0
0
77
681
1.13
0.48
1.1
1.1
1.27
4.83
u/ml
2.29
35
306
206
1918
1.08
0.48
1.0
1.0
—
—
—
0
0
363
3449
1.06
0.47
1.3
1.3
27.62
27.07
iu/l
0.11
325
3023
30
245
1.23
0.46
4.2
3.9
32.28
49.53
mg/l
0.47
24
204
16
210
0.76
0.46
1.1
1.6
—
—
—
0
0
10
69
1.45
0.44
1.0
1.2
—
—
—
0
0
777
7539
1.04
0.43
2.1
2.1
—
—
—
0
0
694
6723
1.04
0.42
2.1
2.0
—
—
—
0
0
5
32
1.56
0.42
1.6
1.5
0.28
0.45
ug/l
—
5
21
206
1932
1.07
0.41
1.4
1.3
229.22
233.13
miu/ml
0.05
106
998
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
33
277
1.19
0.41
3.3
3.5
0.39
0.36
u/ml
0.28
19
150
180
1682
1.07
0.40
1.3
1.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
46
399
1.16
0.40
1.7
2.1
133.43
130.60
g/l
0.57
37
308
474
4565
1.05
0.38
1.5
1.4
—
—
—
0
0
372
3562
1.05
0.38
1.5
1.4
—
—
—
0
0
89
810
1.10
0.37
1.1
1.1
3.22
5.76
u/ml
1.24
41
417
373
3577
1.05
0.37
1.5
1.4
—
—
—
0
0
86
782
1.10
0.37
1.9
1.9
—
—
—
0
0
16
125
1.28
0.37
1.3
1.3
156.31
139.94
mmol/24h
0.41
16
125
73
658
1.11
0.36
1.1
1.1
—
—
—
0
0
11
81
1.36
0.36
1.1
1.1
93.91
95.54
%
0.07
11
81
37
428
0.86
0.36
2.7
2.0
1.87
1.55
ug/l
0.10
30
389
9
122
0.74
0.35
1.3
1.6
—
—
—
0
0
15
117
1.28
0.35
1.1
1.4
12.16
13.60
pmol/l
0.73
15
99
29
245
1.19
0.35
4.3
3.9
20.40
26.75
mg/l
0.68
23
205
6
43
1.40
0.35
1.2
1.2
—
—
—
0
0
373
3585
1.05
0.34
1.5
1.4
—
—
—
0
0
183
1725
1.06
0.34
1.4
1.5
—
—
—
0
0
83
758
1.10
0.33
1.1
1.1
0.84
1.31
u/ml
0.39
30
291
163
1733
0.94
0.33
1.2
1.2
—
—
—
0
0
6
89
0.67
0.33
1.0
1.0
—
—
—
0
0
46
519
0.88
0.33
1.9
2.3
24.38
24.56
mmol/l
0.23
40
481
61
549
1.11
0.32
1.1
1.1
0.05
0.35
u/ml
0.66
15
133
372
3583
1.04
0.32
1.5
1.4
—
—
—
0
0
581
5974
0.97
0.31
3.4
3.3
1.02
1.02
kg/l
0.32
94
957
271
2594
1.05
0.31
1.5
1.5
—
—
—
0
0
26
221
1.18
0.30
1.8
1.8
11.00
23.82
mg/l
—
8
65
317
3047
1.05
0.30
2.0
2.3
2.41
2.41
mmol/l
0.59
272
2647
41
362
1.13
0.30
2.2
2.2
—
—
—
0
0
18
148
1.22
0.29
1.5
1.6
—
—
—
0
0
655
6395
1.03
0.28
1.9
1.8
—
—
—
0
0
393
3804
1.04
0.28
1.6
1.5
—
—
—
0
0
15
183
0.82
0.27
1.2
1.5
0.80
1.28
promille
—
10
133
8
64
1.25
0.27
1.0
2.2
—
—
—
0
0
8
65
1.23
0.27
1.0
1.3
—
—
—
0
0
8
65
1.23
0.27
1.0
1.3
—
—
—
0
0
14
113
1.24
0.26
1.3
1.6
118.50
122.58
nmol/l
0.16
14
113
10
77
1.30
0.26
1.1
1.0
64.74
73.05
ug/l
—
10
70
35
310
1.13
0.26
4.7
7.4
105.87
105.68
mmol/l
0.06
30
276
146
1384
1.06
0.25
4.7
3.5
35.47
38.46
ug/l
0.03
107
971
36
320
1.13
0.25
1.1
1.1
180.45
196.93
mg/l
0.60
30
282
35
393
0.89
0.25
1.5
1.6
—
—
—
0
0
57
522
1.09
0.24
1.1
1.1
—
—
—
0
0
21
244
0.86
0.24
1.1
1.1
1781.86
1490.26
miu/ml
0.70
21
244
6
85
0.71
0.24
1.2
1.3
—
—
—
0
0
68
630
1.08
0.23
1.1
1.2
3.57
3.54
mmol/l
0.12
63
591
93
873
1.07
0.23
2.0
2.1
—
—
—
0
0
67
621
1.08
0.22
1.2
1.4
1092.85
2246.84
e6/l
0.36
53
515
17
200
0.85
0.22
1.4
2.1
—
—
—
0
0
65
602
1.08
0.22
1.1
1.0
1.76
3.95
u/ml
2.03
34
327
5
40
1.25
0.22
1.0
1.4
—
—
—
0
0
25
219
1.14
0.22
1.2
1.7
—
—
—
0
0
49
449
1.09
0.21
1.1
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
26.15
—
0
10
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
51
469
1.09
0.21
1.4
1.3
1.15
1.28
nmol/l
0.42
40
411
8
104
0.77
0.21
1.1
1.2
—
—
—
0
0
210
2024
1.04
0.20
1.5
1.5
—
—
—
0
0
323
3139
1.03
0.20
2.7
2.5
339.10
273.54
ng/l
0.15
140
1413
36
397
0.91
0.20
1.4
1.6
—
—
—
0
0
224
2165
1.04
0.19
1.7
1.5
402.74
283.73
mu/l
0.41
196
1914
23
260
0.88
0.19
1.7
1.4
—
—
—
0
0
34
308
1.11
0.19
2.4
1.3
—
222.86
—
0
7
6
52
1.15
0.19
1.8
1.5
15.45
68.60
u/l
—
6
46
24
270
0.89
0.19
1.5
1.4
485.33
741.19
pmol/l
0.29
24
242
31
280
1.11
0.18
1.1
1.1
1.08
1.04
ratio
0.40
14
107
16
138
1.16
0.17
1.1
1.1
17.07
9.98
u/ml
—
9
91
25
224
1.12
0.17
2.1
1.5
—
—
—
0
0
7
63
1.11
0.17
2.7
2.3
—
—
—
0
0
5
68
0.73
0.17
1.4
2.7
17.44
14.93
umol/l
—
5
68
66
621
1.06
0.17
1.2
1.3
3.04
23.56
e6/l
3.91
47
486
34
371
0.92
0.16
1.1
1.2
—
—
—
0
0
8
70
1.14
0.16
2.0
1.5
—
—
—
0
0
20
225
0.89
0.16
1.1
1.7
—
—
—
0
0
75
710
1.06
0.16
1.1
1.3
420.70
453.31
mg/l
0.29
69
677
36
331
1.09
0.16
1.2
1.1
—
—
—
0
0
8
72
1.11
0.16
2.0
1.5
—
—
—
0
0
15
130
1.15
0.15
1.1
1.1
—
—
—
0
0
45
483
0.93
0.15
3.4
3.3
30.04
21.16
mg/l
0.67
28
293
6
78
0.77
0.15
1.2
2.0
—
—
—
0
0
6
78
0.77
0.15
1.2
2.0
—
—
—
0
0
6
78
0.77
0.15
1.2
2.0
—
—
—
0
0
9
78
1.15
0.15
1.6
1.5
—
—
—
0
0
36
332
1.09
0.15
1.1
1.2
44.80
35.33
mg/l
0.30
26
276
9
80
1.13
0.15
1.1
1.1
—
—
—
0
0
9
82
1.10
0.15
1.0
1.2
—
—
—
0
0
105
1007
1.04
0.14
1.9
2.2
0.32
0.20
e6/l
0.46
99
948
11
93
1.18
0.14
1.5
1.3
5.67
6.45
mmol/l
1.08
11
86
208
2025
1.03
0.14
2.6
2.3
23.96
30.88
u/ml
0.94
203
1961
8
100
0.80
0.13
1.1
1.8
—
—
—
0
0
8
100
0.80
0.13
1.1
1.8
—
—
—
0
0
20
181
1.11
0.12
1.4
1.3
69.00
67.12
umol/l
0.19
20
181
137
1412
0.97
0.12
10.3
6.7
0.25
0.76
mmol/l
0.91
105
1069
116
1199
0.97
0.12
11.5
7.2
121.99
121.89
g/l
0.02
110
1164
110
1063
1.04
0.12
1.4
1.4
25.14
23.22
u/l
0.25
87
885
33
309
1.07
0.10
1.1
1.1
—
—
—
0
0
5
45
1.11
0.09
1.0
1.0
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
12
135
0.89
0.09
1.3
1.1
—
—
—
0
0
15
166
0.90
0.09
1.7
1.8
1.17
2.24
u/field
—
6
87
5
46
1.09
0.09
1.0
1.0
—
—
—
0
0
5
47
1.06
0.09
1.2
1.1
—
—
—
0
0
21
194
1.08
0.09
1.4
1.5
—
—
—
0
0
934
9405
0.99
0.08
1.5
1.5
—
—
—
0
0
5
61
0.82
0.08
1.0
1.1
—
—
—
0
0
5
61
0.82
0.08
1.0
1.1
—
—
—
0
0
11
123
0.89
0.08
1.2
1.8
4.00
3.92
mmol/l
0.33
11
123
11
123
0.89
0.08
1.2
1.8
106.73
105.98
mmol/l
0.65
11
123
32
303
1.06
0.07
2.6
2.5
—
—
—
0
0
8
75
1.07
0.07
1.0
1.0
—
—
—
0
0
8
77
1.04
0.07
1.0
6.8
—
59.85
—
0
13
20
186
1.08
0.07
1.7
1.3
—
—
—
0
0
7
82
0.85
0.07
1.0
1.1
—
—
—
0
0
14
153
0.91
0.07
1.1
1.0
—
—
—
0
0
9
85
1.06
0.07
1.0
1.2
—
—
—
0
0
68
701
0.97
0.07
1.9
1.9
—
—
—
0
0
36
344
1.05
0.06
2.3
2.5
0.81
0.84
nmol/l
0.08
28
302
80
779
1.03
0.06
1.2
1.1
—
—
—
0
0
37
354
1.05
0.06
3.2
4.2
37.59
90.91
u/ml
—
8
119
12
131
0.92
0.05
1.2
1.3
—
—
—
0
0
33
343
0.96
0.04
1.1
1.2
—
—
—
0
0
21
221
0.95
0.04
1.0
1.1
0.98
1.01
u/l
—
10
89
16
150
1.07
0.04
1.6
2.4
30.31
32.09
pg
0.56
16
150
58
594
0.98
0.04
1.1
1.2
—
—
—
0
0
118
1163
1.02
0.04
1.5
1.5
—
—
—
0
0
139
1407
0.99
0.03
10.2
6.7
4.99
4.97
kpa
0.07
133
1353
139
1407
0.99
0.03
10.2
6.7
14.35
13.99
kpa
0.26
133
1351
79
776
1.02
0.03
1.2
1.1
—
—
—
0
0
376
3783
0.99
0.03
1.5
1.6
—
—
—
0
0
1422
14190
1.00
0.03
2.6
2.4
—
—
—
0
0
20
191
1.05
0.03
1.2
1.3
—
62.30
—
0
10
23
221
1.04
0.03
1.1
1.1
—
—
—
0
0
503
5046
1.00
0.02
1.7
1.8
—
—
—
0
0
82
810
1.01
0.02
1.7
2.5
1.03
1.21
mmol/l
0.25
49
568
125
1241
1.01
0.01
10.8
7.0
96.25
96.62
%
0.19
118
1195
25
257
0.97
0.01
1.9
1.9
—
—
—
0
0
25
256
0.98
0.00
1.4
1.7
—
—
—
0
0
84
846
0.99
0.00
1.7
2.5
5.00
5.08
kpa
0.50
77
812
110
1105
1.00
0.00
1.3
1.4
0.37
0.53
nmol/l
2.25
90
904
21
208
1.01
0.00
1.8
1.6
—
—
—
0
0
10
97
1.03
0.00
1.0
1.1
—
—
—
0
0
7
71
0.99
-0.00
1.3
3.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
1.2
1.6
—
—
—
0
0
8
82
0.98
-0.00
1.0
1.2
—
—
—
0
0
8
82
0.98
-0.00
2.0
1.4
—
—
—
0
0
8
85
0.94
-0.00
3.5
3.2
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
53
0.94
-0.00
1.0
1.3
—
—
—
0
0
5
52
0.96
-0.00
1.6
2.4
119.60
157.67
nmol/l
—
5
45
0
5
0.00
-0.00
0.0
1.2
—
1.14
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
87.60
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.4
—
—
—
0
0
6
66
0.91
-0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.2
—
—
—
0
0
6
65
0.92
-0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
4.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
94
0.96
-0.00
3.6
2.4
1.69
1.61
nmol/l
—
9
83
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.0
1.1
—
—
—
0
0
7
69
1.01
-0.00
1.1
1.5
7.97
7.53
ug/l
—
7
69
5
59
0.85
-0.00
1.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint O15_ICP_EXMORE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| O15_ICP_EXMORE | 0.646 [0.5, 0.83] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.437 |
During the follow-up period (1.1.1998 — 31.12.2019), 78 out of 13331 females with O15_ICP_EXMORE died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have O15_ICP_EXMORE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.056% | No data |
| 5 | 0.38% | No data |
| 10 | 1.081% | No data |
| 15 | 1.972% | No data |
| 20 | 3.48% | No data |
Relationships between endpoints
↥Index endpoint: O15_ICP_EXMORE – Intrahepatic Cholestasis of Pregnancy (ICP) , excluding more controls
GWS hits: 30
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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