No definition available.
Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8, excluding more controls
O15_ICP_WIDE_EXMORE
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleonly females |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
- Control exclude
- !(O15_DELIVERY, O15_DELIVERY_PROXY)
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF5
- Parent code in ICD-10
- O26
- Name in latin
- Morbositates hepatis in graviditate, intra labores et/sive in puerperio
Similar endpoints
↥List of similar endpoints to
Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8, excluding more controls
based on the number of shared cases.
Similar with more cases:
- Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8
- Pregnancy, childbirth and the puerperium
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 23532 | 23532 | - |
| Only index persons | 23124 | 23124 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.67 | 0.67 | - |
| Only index persons | 0.85 | 0.85 | - |
| Median age at first event (years) | |||
| Whole population | - | 29.44 | - |
| Only index persons | - | 29.44 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3612 | 3612 | - |
| Unadjusted period prevalence (%) | 1.23 | 1.23 | - |
| Median age at first event (years) | 29.60 | 29.60 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 3250
- Matched controls
- 32510
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A05AA02
ATC
ursodeoxycholic acid; oral
69.2
323.0
809
155
63900
ICD-8 Finland
Other toxaemias of pregnancy and the puerperium, Pruritus
+∞
323.0
568
*
6467A
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Liver disorders in pregnancy[HEPATOSIS GRAVIDARUM]
+∞
323.0
680
*
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
16384.0
323.0
2068
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.0
59.6
370
1316
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
2.3
47.9
481
2244
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.3
45.1
482
2314
63998
ICD-8 Finland
Other toxaemias of pregnancy and the puerperium, Alia definitae
16.9
44.3
71
43
O80.8
ICD-10 Finland
Other single spontaneous delivery
2.2
32.5
377
1864
63901
ICD-8 Finland
Other toxaemias of pregnancy and the puerperium, Interus gravis
+∞
27.1
26
*
63909
ICD-8 Finland
Other toxaemias of pregnancy and the puerperium, Necrosis acuta et subacuta hepatis
+∞
25.0
24
*
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.7
24.1
636
4157
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
2.4
23.3
206
892
O30.0
ICD-10 Finland
Twin pregnancy
2.8
22.9
149
542
W84
ICPC
Pregnancy high risk
2.0
20.4
276
1444
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
2.5
19.4
154
631
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
1.4
18.7
1040
8003
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
3.6
17.9
82
234
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
1.6
17.8
575
3928
5742A
ICD-9 Finland
Cholelithiasis, Calculus of gallbladder without mention of cholecystitis[CHOLECYSTOLITHIASIS SINE CHOLECYSTITIDE,SINE OBSTR]
3.6
17.7
80
226
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
4.0
17.1
69
177
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
1.5
16.4
585
4084
MAC96
NOMESCO Finland
Other induction or advancement of labour
2.0
14.3
182
932
O60
ICD-10 Finland
Preterm labour and delivery
1.9
12.5
180
963
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
1.4
11.9
564
4148
L29.9
ICD-10 Finland
Pruritus, unspecified
2.6
11.9
87
345
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
1.9
11.4
173
946
MAA00
NOMESCO Finland
Amniocentesis
2.0
11.3
153
803
6663
FHL
Cholecystectomy and cholangiography
3.7
11.1
47
128
XMA22
NOMESCO Finland
General examination of pregnant woman
1.5
10.9
367
2512
A10BX01
ATC
guar gum; systemic
2.7
10.8
70
260
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
10.6
1172
9856
6510B
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, SYNNYTYKSEN AIKANA]
3.7
10.3
43
117
K76.9
ICD-10 Finland
Liver disease, unspecified
3.2
10.2
51
159
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
9.9
306
2054
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
2.0
9.5
124
646
6467X
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Liver disorders in pregnancy[HEPATOPATHIA ALIA GRAVIDARUM]
+∞
9.4
9
*
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
1.7
9.3
211
1311
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
1.5
9.3
361
2552
63902
ICD-8 Finland
NA
+∞
8.3
8
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
8.2
480
3652
L04AX01
ATC
azathioprine; systemic
1.9
8.2
114
608
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
1.5
8.1
268
1826
S02
ICPC
Pruritus
2.0
8.0
100
511
K80.1
ICD-10 Finland
Calculus of gallbladder with other cholecystitis
2.5
8.0
62
255
6510A
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, RASKAUDEN AIKANA]
4.1
8.0
29
71
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
1.8
7.9
129
727
1413
FHL
Laparoscopy and other therapeutic procedure
2.1
7.9
88
432
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
1.6
7.8
221
1455
O84.2
ICD-10 Finland
Multiple delivery, all by caesarean section
3.2
7.7
38
120
V230A
ICD-9 Finland
Supervision of high-risk pregnancy, Pregnancy with history of infertility
2.5
7.6
57
232
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
4.2
7.6
27
65
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
1.3
7.6
979
8310
G03DA04
ATC
progesterone; systemic, rectal, vaginal
1.7
7.4
148
891
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
1.3
7.3
628
5054
O26.0
ICD-10 Finland
Excessive weight gain in pregnancy
5.8
7.2
19
33
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.3
7.2
579
4618
8811
FHL
Cesarean section
1.5
7.2
254
1757
K50.9
ICD-10 Finland
Crohn disease, unspecified
2.6
7.1
47
180
O98.4
ICD-10 Finland
Viral hepatitis complicating pregnancy, childbirth and the puerperium
6.0
7.1
18
30
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
3.4
7.0
32
96
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
1.9
7.0
100
542
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
6.3
6.9
17
27
O61.0
ICD-10 Finland
Failed medical induction of labour
2.2
6.9
69
324
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
2.7
6.9
45
170
K83.0
ICD-10 Finland
Cholangitis
3.2
6.8
33
104
A02BC02
ATC
pantoprazole; systemic
1.2
6.8
1732
15754
B18.2
ICD-10 Finland
Chronic viral hepatitis C
2.9
6.6
36
123
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
2.0
6.5
84
436
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
3.5
6.5
28
81
6662
FHL
Cholecystectomy
3.0
6.5
34
114
Z22.5
ICD-10 Finland
Carrier of viral hepatitis
14.3
6.4
10
7
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
1.9
6.4
85
450
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
6.2
616
5050
K30
ICD-10 Finland
Functional dyspepsia
1.4
6.0
282
2065
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
810
1205
8.38
307.65
6.2
1.5
10.01
4.09
umol/l
19.22
714
846
292
580
5.39
140.26
1.3
1.3
108.05
108.98
u/ml
0.07
56
146
293
592
5.30
138.03
1.2
1.2
203.38
263.87
u/ml
4.48
235
383
303
637
5.10
136.37
1.2
1.2
—
—
—
0
0
302
640
5.06
134.62
1.3
1.3
14.08
17.13
u/ml
—
5
17
110
171
6.60
67.72
1.1
1.1
—
—
—
0
0
540
3139
1.85
34.28
2.4
2.4
5.98
6.17
umol/l
0.10
477
2675
1774
14201
1.49
29.55
5.2
5.4
9.58
9.52
umol/l
0.11
1678
13393
1319
10028
1.50
27.84
3.5
2.9
33.59
29.45
u/l
2.18
1263
9593
193
839
2.37
26.59
1.4
1.2
72.00
184.25
titre
0.82
15
73
2486
21829
1.45
22.17
7.6
6.7
79.16
72.43
u/l
13.32
2348
20634
299
1700
1.83
19.95
1.8
1.8
1.48
1.36
g/l
0.32
273
1571
3445
32782
2.11
19.91
11.3
8.7
30.86
23.70
u/l
37.37
3375
31877
363
2235
1.69
18.32
2.4
2.6
10.45
10.34
g/l
0.24
331
2052
325
2098
1.60
13.53
2.2
2.1
0.22
0.22
g/l
0.28
301
1981
1574
13508
1.29
12.47
8.4
7.9
0.00
0.00
e9/l
1.20
1300
11164
2395
21747
1.30
12.03
3.3
2.7
40.07
34.67
u/l
3.28
2267
20752
884
7046
1.34
11.90
1.5
1.4
2.08
2.13
g/l
0.63
557
4472
1606
13910
1.28
11.51
6.4
5.5
2.85
2.82
%
0.25
1525
12932
1614
13989
1.28
11.50
6.6
5.7
8.03
7.90
%
1.03
1546
13135
1550
13393
1.28
11.23
6.5
5.5
0.73
0.69
%
1.96
1480
12469
1086
8983
1.30
11.06
2.4
2.4
59.07
55.95
u/l
0.42
1019
8360
835
6693
1.32
10.64
4.0
3.1
99.38
98.68
%
0.41
807
6470
1658
14508
1.26
10.60
6.4
5.5
29.95
29.81
%
0.25
1578
13565
107
539
2.02
10.36
1.9
1.4
9.03
6.32
iu/ml
—
6
9
1635
14324
1.26
10.21
6.2
5.3
56.05
56.29
%
0.42
1565
13427
56
223
2.54
9.52
1.1
1.1
315.49
289.81
mg/l
0.93
45
200
1260
10785
1.26
9.38
4.6
4.2
36.37
36.63
g/l
0.99
1173
10112
326
2314
1.45
8.68
3.1
4.2
244.56
234.22
u/l
0.17
309
2186
49
192
2.57
8.64
1.3
1.3
272.86
176.88
titre
0.34
14
48
1725
15413
1.23
8.35
6.3
5.3
1.93
1.96
e9/l
0.65
1574
13892
47
189
2.51
7.89
1.1
1.0
—
—
—
0
0
500
3874
1.34
7.87
2.1
2.1
14.41
14.46
umol/l
0.06
466
3610
1732
15551
1.22
7.78
6.4
5.4
0.18
0.18
e9/l
0.12
1577
13968
1888
17106
1.22
7.71
3.2
2.9
64.71
71.83
ug/l
2.59
1798
16216
72
358
2.03
7.34
1.0
1.1
1.41
1.45
g/l
0.39
61
321
403
3064
1.35
7.18
2.2
2.2
23.41
23.86
%
0.26
347
2647
2449
22852
1.22
7.14
4.4
3.8
10.28
9.86
mm/h
1.09
2317
21576
344
2552
1.38
7.14
2.5
2.2
35.34
35.74
u/l
0.04
312
2184
929
7875
1.24
7.14
3.0
2.7
34.21
72.23
e6/l
1.22
679
5914
1451
12928
1.20
6.71
2.4
2.2
76.94
76.11
nmol/l
0.57
1347
12064
823
6936
1.24
6.60
2.3
2.1
2.56
2.70
mg/l
1.15
727
6004
112
668
1.70
6.48
4.3
3.5
780.16
389.18
u/ml
0.31
97
569
443
3476
1.31
6.35
2.2
2.1
2.48
2.47
g/l
0.07
407
3220
1123
9827
1.21
6.16
1.8
1.8
102.45
100.02
pmol/l
0.89
569
5200
844
7180
1.23
6.15
3.0
2.6
0.20
0.30
e6/l
1.45
617
5307
76
412
1.86
6.09
1.3
1.3
—
—
—
0
0
128
805
1.61
6.06
2.0
1.9
1.21
1.35
g/l
1.04
110
700
994
8610
1.21
6.04
1.3
1.3
1.02
1.56
u/ml
2.06
288
2578
170
1143
1.51
6.01
1.4
1.3
—
—
—
0
0
2770
26358
1.22
5.79
4.0
3.8
—
—
—
0
0
3118
30054
1.27
5.78
5.3
5.1
1.69
1.89
mu/l
1.38
2951
28480
2962
28408
1.24
5.58
10.0
8.8
90.29
90.13
ml/min/173m2
0.17
2475
23305
35
146
2.41
5.53
2.9
2.9
8.55
7.61
mg/l
0.33
28
106
119
753
1.60
5.53
2.4
1.7
531.43
477.78
titre
—
7
36
1865
17180
1.18
5.48
8.4
7.9
3.83
3.89
e9/l
0.64
1660
15162
2856
27306
1.22
5.45
13.9
12.4
13.45
13.47
%
0.25
2821
26804
768
6543
1.22
5.44
1.3
1.3
10.26
9.54
u/ml
0.13
294
2828
1357
12235
1.17
5.06
5.4
5.3
1.22
1.22
mmol/l
1.36
1159
10343
46
228
2.03
4.85
1.0
1.1
—
—
—
0
0
471
3857
1.25
4.80
2.6
2.4
4.87
4.73
e6/l
0.06
238
2004
785
6807
1.20
4.55
1.3
1.3
25.61
27.54
iu/ml
0.17
235
2189
2792
26776
1.19
4.46
4.7
4.5
14.38
14.36
pmol/l
0.19
2608
25277
611
5186
1.21
4.44
1.4
1.4
21.86
21.52
nmol/l
0.22
528
4558
562
4750
1.22
4.25
3.0
2.3
97.07
102.01
ug/g
0.19
451
3719
1203
10866
1.16
4.19
5.1
4.7
1.22
1.22
mmol/l
1.57
1130
9914
229
2959
0.76
3.97
5.1
5.0
—
—
—
0
0
777
6822
1.18
3.84
2.2
2.1
615.94
2716.69
umol/l
5.09
683
6068
48
264
1.83
3.81
1.3
1.2
47.05
59.09
u/l
0.98
38
179
642
5564
1.19
3.70
2.5
2.3
9.28
8.18
e6/l
0.30
546
4819
32
156
2.06
3.61
1.9
1.5
1.53
3.62
u/l
1.64
19
77
3314
32448
1.26
3.56
12.1
11.0
66.02
65.95
umol/l
0.08
3309
32436
46
257
1.80
3.50
1.0
1.1
8.09
10.63
iu/ml
0.28
12
68
38
200
1.91
3.48
1.4
1.4
—
—
—
0
0
3132
30501
1.20
3.47
11.0
10.1
3.89
3.90
mmol/l
1.03
3061
29664
3122
30408
1.20
3.38
10.9
10.0
139.69
139.64
mmol/l
0.53
3050
29655
400
3350
1.22
3.33
2.4
2.0
29.01
28.94
s
0.08
383
3230
488
4176
1.19
3.24
2.5
2.3
2.25
1.07
e6/l
0.59
254
2309
309
2534
1.24
3.15
1.3
1.3
196.80
147.83
u/ml
0.28
291
2356
813
7265
1.15
3.15
1.9
1.7
1.03
0.89
mg/l
0.76
600
5420
151
1131
1.35
3.10
1.4
1.4
—
—
—
0
0
354
2952
1.22
3.09
1.9
2.1
380.51
367.82
nmol/l
0.61
332
2735
129
946
1.38
3.03
2.5
2.2
3.94
3.60
g/l
1.74
118
887
806
7219
1.15
3.02
1.9
1.9
133.42
138.52
u/l
0.12
772
6855
159
1210
1.33
2.95
1.9
2.0
40.10
38.84
u/l
0.36
146
1118
61
389
1.58
2.91
2.0
1.7
36.00
23.37
iu/ml
—
5
19
47
281
1.68
2.89
1.1
1.2
—
—
—
0
0
1028
9396
1.13
2.81
1.7
1.7
—
—
—
0
0
422
3616
1.19
2.78
3.1
3.1
0.83
0.82
mmol/l
0.97
398
3401
239
1942
1.25
2.69
2.0
2.6
1.64
1.72
%
0.70
210
1748
2968
28902
1.15
2.68
3.7
3.6
5.60
5.60
mmol/l
0.10
2774
27141
323
2711
1.21
2.67
2.7
3.4
4.56
4.54
pmol/l
0.14
297
2449
44
265
1.67
2.66
1.2
1.1
—
—
—
0
0
2288
21936
1.12
2.64
4.5
4.1
654.22
1705.32
e6/l
0.85
23
234
2687
26011
1.13
2.60
4.6
4.3
37.49
37.56
mmol/mol
0.19
2536
24575
29
156
1.87
2.56
1.2
1.2
—
—
—
0
0
47
292
1.62
2.53
1.2
1.1
—
55.04
—
0
5
806
7299
1.13
2.53
1.6
1.6
1.25
1.33
mmol/l
1.69
706
6306
1716
16234
1.11
2.48
4.2
3.8
6.20
6.26
mmol/l
0.65
1553
14438
201
1618
1.26
2.47
1.2
1.3
0.29
1.07
u/ml
2.22
16
135
163
1285
1.28
2.39
1.7
1.7
—
—
—
0
0
87
625
1.40
2.38
1.2
1.1
12.11
11.61
au/ml
0.03
12
36
518
4578
1.15
2.33
2.5
2.5
669.35
566.53
ng/l
0.24
419
3745
83
594
1.41
2.33
2.3
2.4
9.83
10.29
g/l
0.68
77
516
66
453
1.47
2.31
3.5
5.2
123.71
395.41
iu/ml
—
7
54
71
497
1.44
2.26
1.8
1.6
16640.50
6809.71
e6/l
0.78
52
367
423
3692
1.17
2.25
1.6
1.6
1.33
1.32
%
0.15
370
3295
76
543
1.41
2.17
1.5
1.4
—
—
—
0
0
181
1467
1.25
2.14
7.6
6.7
7.82
7.18
mmol/l
0.73
173
1421
71
504
1.42
2.11
2.3
2.1
39.02
38.86
g/l
0.09
66
454
185
1509
1.24
2.07
2.2
2.6
66.86
67.13
g/l
0.21
171
1396
284
2422
1.19
2.03
2.5
2.6
—
—
—
0
0
48
321
1.50
1.95
1.8
2.3
—
800.09
—
0
11
129
1017
1.28
1.95
1.2
1.2
—
—
—
0
0
78
572
1.37
1.95
2.9
2.3
0.40
0.54
g/l
0.24
73
513
127
1000
1.28
1.94
1.3
1.3
6.34
7.95
u/ml
0.18
16
174
60
421
1.43
1.93
1.2
1.2
—
—
—
0
0
60
421
1.43
1.93
1.2
1.2
—
—
—
0
0
147
1181
1.26
1.91
2.0
2.0
—
—
—
0
0
117
914
1.29
1.91
1.3
1.3
72.23
39.48
u/ml
—
9
97
954
8856
1.10
1.90
2.9
3.1
2.35
2.35
mmol/l
0.14
839
7968
420
3722
1.15
1.85
1.7
1.6
1126.46
1193.30
nmol/l
0.91
339
2974
11
46
2.40
1.85
1.2
1.2
—
—
—
0
0
48
326
1.48
1.83
2.2
2.8
1.62
1.41
%
0.21
41
254
80
1062
0.75
1.83
1.3
1.3
2.93
4.05
ug/l
1.53
74
976
84
632
1.34
1.80
3.6
3.6
57.35
57.06
%
0.09
84
632
124
984
1.27
1.80
1.3
1.3
6.51
5.62
u/ml
0.08
11
99
9
35
2.58
1.80
1.0
1.2
—
—
—
0
0
751
6910
1.11
1.77
3.7
3.0
7.28
7.28
mmol/l
0.01
652
5980
58
412
1.41
1.77
2.0
1.3
—
215.00
—
0
8
21
117
1.80
1.74
1.0
1.1
—
—
—
0
0
201
2379
0.84
1.72
1.4
1.5
—
—
—
0
0
3207
31583
1.14
1.69
11.8
10.4
17.16
18.38
mg/l
1.54
2504
24597
670
6145
1.11
1.68
4.4
3.8
9.34
9.61
mg/mmol
0.06
408
3722
292
2543
1.16
1.66
2.3
2.3
19.54
22.96
au/ml
0.29
12
191
5
14
3.57
1.61
1.0
1.0
—
—
—
0
0
54
387
1.40
1.59
2.4
2.6
14.83
93.18
ug/min
3.26
37
240
15
77
1.95
1.59
1.4
7.2
11863.60
63.89
mg/l
—
10
54
6
20
3.00
1.58
1.0
1.2
—
—
—
0
0
87
673
1.30
1.58
2.2
2.3
—
—
—
0
0
87
673
1.30
1.58
2.2
2.3
3.70
3.74
g/l
0.12
69
478
87
673
1.30
1.58
2.2
2.3
7.29
7.25
g/l
0.09
74
517
130
1057
1.24
1.57
2.3
2.0
0.23
0.23
g/l
0.14
125
998
383
3415
1.14
1.57
2.6
2.2
6722.92
6853.20
u/l
0.03
168
1552
88
683
1.30
1.56
1.2
1.3
—
—
—
0
0
107
855
1.26
1.51
1.6
1.5
—
—
—
0
0
43
299
1.44
1.51
1.3
1.2
—
—
—
0
0
96
1207
0.79
1.50
1.3
1.2
12.36
12.17
u/l
0.04
80
1039
43
300
1.44
1.48
1.3
1.2
—
—
—
0
0
3034
29834
1.11
1.45
12.9
10.9
39.28
39.34
%
0.21
2473
23984
384
3444
1.13
1.45
1.2
1.2
179.40
158.31
iu/ml
0.41
152
1428
639
5894
1.10
1.45
3.6
3.1
381.71
543.24
mg/l
0.37
391
3514
18
102
1.77
1.44
31.3
23.9
111.50
112.98
ug/l
0.03
18
83
156
1309
1.20
1.41
2.3
2.5
72.20
100.51
ng/l
1.89
137
1180
135
1117
1.22
1.41
1.3
1.3
85.86
31.18
u/ml
—
5
85
43
304
1.42
1.40
1.3
1.2
—
—
—
0
0
43
304
1.42
1.40
1.3
1.2
—
—
—
0
0
43
304
1.42
1.40
1.3
1.2
—
—
—
0
0
136
1132
1.21
1.35
1.7
2.1
3.25
4.30
iu/l
1.67
47
461
107
869
1.24
1.35
13.8
7.7
24.02
24.10
mmol/l
0.10
102
824
3043
29954
1.10
1.33
3.8
3.6
4.81
4.88
mmol/l
4.51
2903
28459
22
136
1.62
1.32
1.3
1.7
—
—
—
0
0
134
1117
1.21
1.32
1.4
1.5
—
—
—
0
0
47
342
1.38
1.32
3.5
2.8
29.34
33.95
umol/l
1.29
38
301
592
5471
1.10
1.30
1.6
1.5
15238528.58
36880165.23
pmol/l
0.69
525
4756
47
343
1.38
1.30
1.1
1.5
—
2933.33
—
0
6
35
242
1.45
1.30
2.0
1.3
—
—
—
0
0
22
137
1.61
1.29
1.1
1.4
—
—
u/ml
—
0
0
82
650
1.27
1.28
2.3
2.3
2.83
3.05
g/l
1.57
72
495
343
3085
1.12
1.26
3.7
3.6
33.20
32.98
%
0.15
256
2300
188
1624
1.17
1.25
9.4
5.4
1.20
1.23
mmol/l
0.18
183
1571
93
752
1.24
1.24
2.0
2.1
10.33
10.12
mg/l
0.10
87
711
35
491
0.71
1.22
1.5
1.4
32.56
30.58
nmol/l
0.15
28
442
462
4233
1.10
1.22
3.0
2.8
284.90
283.68
ng/l
0.00
255
2296
25
164
1.53
1.20
1.2
1.1
96.27
97.30
%
0.09
11
63
128
1517
0.84
1.19
2.1
2.1
—
—
—
0
0
37
264
1.41
1.18
1.7
1.6
53.33
50.62
%
0.14
24
156
258
2292
1.14
1.17
10.9
13.0
1.08
1.10
inr
0.14
51
413
298
2674
1.12
1.16
5.2
4.6
1.05
1.04
mmol/l
0.40
279
2504
13
72
1.81
1.15
1.1
1.1
—
—
—
0
0
159
1367
1.17
1.14
2.1
2.6
65.81
72.15
e9/l
1.80
112
1013
261
2326
1.13
1.13
7.9
5.9
104.96
104.74
mmol/l
0.46
256
2281
93
1129
0.82
1.12
5.8
7.1
24.84
24.45
mmol/l
0.53
84
1056
922
8739
1.07
1.10
2.6
2.6
25.88
29.06
ng/l
0.16
385
3956
231
2047
1.14
1.10
3.2
3.2
1.23
1.23
mmol/l
0.79
211
1786
1682
16266
1.06
1.10
3.5
3.3
0.00
0.00
estimate
0.69
395
3293
3065
30244
1.09
1.08
4.0
3.9
2.88
2.93
mmol/l
2.91
2897
28536
807
7620
1.08
1.07
2.0
1.9
—
—
—
0
0
122
1032
1.19
1.07
1.5
1.6
0.05
17.93
iu/ml
0.51
21
188
71
568
1.26
1.07
1.2
1.1
—
—
—
0
0
10
180
0.55
1.06
1.9
2.5
—
—
—
0
0
97
804
1.21
1.06
4.5
3.2
23.93
24.26
mmol/l
0.48
84
717
39
522
0.74
1.05
1.4
1.6
—
—
—
0
0
57
446
1.28
1.03
2.9
2.8
24.67
24.64
mmol/l
0.02
48
394
2904
28610
1.08
1.02
3.4
3.3
1.12
1.19
mmol/l
9.22
2765
27073
28
392
0.71
1.01
1.4
1.4
—
—
—
0
0
343
3132
1.11
1.00
1.7
1.6
—
—
—
0
0
405
3732
1.10
0.98
1.6
1.6
—
—
—
0
0
0
29
0.00
0.97
0.0
1.1
—
17.90
—
0
10
230
2058
1.13
0.97
1.8
1.7
—
—
—
0
0
191
1691
1.14
0.96
1.5
1.6
—
—
—
0
0
13
77
1.69
0.95
1.6
1.7
—
—
iu/ml
—
0
0
38
501
0.76
0.95
1.1
1.1
2.50
19990.67
iu/ml
—
6
134
72
589
1.23
0.92
1.4
1.2
2.29
4.64
u/ml
2.46
28
221
74
608
1.22
0.91
1.3
1.2
1.28
2.76
u/ml
2.03
25
189
181
1604
1.14
0.90
1.8
1.6
2.92
3.37
mg/l
0.41
135
1081
3019
29823
1.08
0.89
3.8
3.6
1.57
1.56
mmol/l
0.16
2874
28269
31
228
1.36
0.88
1.2
1.2
—
—
—
0
0
3539
35242
1.21
0.86
17.8
15.6
266.33
266.28
e9/l
0.02
3484
34641
23
161
1.43
0.86
1.2
1.1
101.36
102.33
%
0.07
11
63
29
212
1.37
0.86
1.2
1.1
—
—
—
0
0
17
252
0.67
0.86
1.5
1.9
13.14
12.75
%
—
7
130
108
926
1.17
0.86
1.2
1.1
2.03
1.47
u/ml
0.29
38
333
41
526
0.78
0.86
1.5
1.6
—
—
—
0
0
6
31
1.94
0.84
1.2
1.1
—
—
—
0
0
90
763
1.18
0.82
1.1
1.1
1.74
1.51
u/ml
0.08
21
195
191
1711
1.12
0.82
3.4
3.0
72.99
72.03
ng/l
0.06
170
1521
1685
16400
1.05
0.80
4.9
4.5
0.00
0.00
estimate
0.80
405
3388
1696
16517
1.05
0.79
3.6
3.4
0.00
0.00
estimate
1.57
411
3360
19
131
1.45
0.78
1.2
1.1
—
—
—
0
0
5
96
0.52
0.78
4.4
2.6
—
—
—
0
0
68
566
1.21
0.77
2.8
2.0
151.53
258.74
ug/l
0.83
58
501
123
1078
1.15
0.76
3.4
2.7
1.81
1.57
mmol/l
0.33
80
789
5
24
2.08
0.74
1.2
1.0
8.16
8.15
mmol/l
—
5
24
672
7059
0.94
0.74
3.7
3.6
1.02
1.02
kg/l
0.26
117
1131
22
158
1.39
0.74
1.3
1.6
0.77
2.99
u/field
1.89
13
108
22
158
1.39
0.74
1.1
1.2
—
—
—
0
0
9
55
1.64
0.73
1.0
1.3
—
—
—
0
0
5
25
2.00
0.72
1.2
1.1
—
—
—
0
0
120
1055
1.14
0.72
1.5
1.5
—
—
—
0
0
28
211
1.33
0.72
2.6
2.9
—
—
—
0
0
34
264
1.29
0.71
1.3
1.3
—
—
—
0
0
27
203
1.33
0.70
1.9
1.5
48.22
41.03
%
0.40
19
118
48
390
1.23
0.70
1.1
1.1
95.81
94.09
%
0.19
48
361
94
814
1.16
0.70
1.7
1.5
6.53
6.68
mmol/l
0.23
63
576
22
297
0.74
0.69
1.5
1.4
—
—
—
0
0
30
387
0.77
0.69
1.1
1.1
—
—
—
0
0
13
85
1.53
0.69
1.1
1.1
—
—
—
0
0
5
27
1.85
0.68
1.4
1.1
—
—
—
0
0
3539
35268
1.17
0.66
17.8
15.7
6.61
6.69
e9/l
1.30
3481
34594
140
1252
1.12
0.66
3.1
2.6
4.73
4.60
kpa
0.24
134
1210
3539
35269
1.17
0.65
17.7
15.6
4.44
4.44
e12/l
0.10
3480
34626
198
2164
0.91
0.64
2.3
2.2
72.83
75.39
ml/min/173m2
0.46
72
779
5
29
1.73
0.64
1.2
2.3
0.60
0.86
u/field
—
5
29
233
2146
1.09
0.63
1.1
1.0
—
—
—
0
0
10
63
1.59
0.61
1.2
1.1
—
—
—
0
0
57
481
1.19
0.60
2.5
2.4
—
—
—
0
0
43
353
1.22
0.60
1.8
1.6
—
—
—
0
0
20
266
0.75
0.59
1.4
1.5
—
—
—
0
0
18
243
0.74
0.59
1.4
2.0
—
—
—
0
0
361
3397
1.07
0.58
1.3
1.3
28.57
28.17
iu/l
0.08
322
2996
87
762
1.15
0.58
1.4
1.3
324.91
310.62
ug/g
0.27
43
391
664
6367
1.05
0.57
2.0
1.9
—
—
—
0
0
744
7156
1.05
0.57
2.1
2.0
—
—
—
0
0
3539
35281
1.15
0.57
17.9
15.7
132.19
132.85
g/l
3.24
3515
34991
6
37
1.62
0.55
1.2
1.1
—
—
—
0
0
34
275
1.24
0.55
1.1
1.2
—
—
—
0
0
6
38
1.58
0.54
1.2
1.1
—
—
—
0
0
301
2829
1.07
0.52
1.9
1.8
—
—
—
0
0
125
1131
1.11
0.52
3.7
2.8
5.12
5.12
kpa
0.02
113
1057
34
278
1.23
0.51
1.1
1.2
—
—
—
0
0
74
650
1.14
0.50
1.1
1.1
1.02
4.63
u/ml
5.71
31
258
236
2203
1.08
0.50
4.2
3.7
59.63
34.70
ug/l
0.24
179
1636
135
1233
1.10
0.48
2.6
2.4
0.31
0.22
e6/l
0.42
128
1172
11
76
1.45
0.48
2.2
3.1
—
—
—
0
0
29
355
0.82
0.48
1.5
1.7
—
—
—
0
0
30
365
0.82
0.47
1.2
1.6
—
—
—
0
0
377
3585
1.06
0.47
1.7
1.7
—
—
—
0
0
129
1178
1.10
0.46
1.1
1.1
8.14
6.18
u/ml
0.10
18
179
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
28
227
1.24
0.46
2.0
1.7
127.47
123.01
%
0.13
28
214
76
674
1.13
0.46
1.4
1.6
—
—
—
0
0
33
273
1.21
0.46
1.1
1.2
0.62
1.31
u/ml
—
9
97
92
828
1.11
0.44
1.1
1.1
3.14
5.59
u/ml
1.20
42
418
157
1696
0.92
0.44
11.2
7.1
119.09
121.17
g/l
0.72
150
1634
81
725
1.12
0.43
3.3
5.1
1.75
1.72
%
0.06
75
675
14
104
1.35
0.43
1.1
1.0
—
—
—
0
0
117
1070
1.10
0.42
2.2
2.0
—
—
—
0
0
17
131
1.30
0.42
1.2
1.2
—
—
—
0
0
217
2038
1.07
0.41
1.7
1.5
410.86
284.41
mu/l
0.42
190
1800
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
21
261
0.80
0.41
1.1
1.1
—
—
—
0
0
201
2143
0.93
0.41
1.5
1.4
—
—
—
0
0
8
59
1.36
0.41
1.1
1.2
—
—
—
0
0
5
34
1.47
0.40
1.0
1.0
—
—
—
0
0
28
336
0.83
0.40
1.6
1.5
—
—
—
0
0
166
1547
1.08
0.40
3.8
3.0
5.79
5.81
kpa
0.10
161
1497
12
88
1.36
0.40
2.4
2.4
—
—
—
0
0
7
101
0.69
0.39
1.9
1.6
—
—
—
0
0
7
104
0.67
0.39
1.9
1.6
—
—
—
0
0
72
802
0.90
0.39
1.2
1.2
—
—
—
0
0
639
6188
1.04
0.39
1.6
1.5
—
—
—
0
0
25
205
1.22
0.39
1.6
1.9
0.70
2.11
u/field
—
10
99
86
779
1.11
0.39
1.1
1.1
0.81
1.30
u/ml
0.44
32
296
427
4102
1.05
0.38
1.5
1.5
—
—
—
0
0
28
334
0.84
0.38
1.5
1.4
—
—
—
0
0
35
298
1.18
0.38
1.9
1.9
17.60
26.56
mg/l
—
8
81
46
401
1.15
0.38
2.0
1.7
—
—
—
0
0
56
496
1.13
0.37
1.5
2.1
131.16
129.27
g/l
0.31
44
378
8
113
0.71
0.37
3.6
2.1
1.17
1.16
ug/l
—
8
108
9
69
1.31
0.37
1.0
1.5
—
—
—
0
0
9
69
1.31
0.37
1.0
1.5
—
—
—
0
0
126
1360
0.92
0.37
2.1
2.0
12.19
4.85
ug/l
1.24
110
1206
19
235
0.81
0.36
1.5
1.6
—
—
—
0
0
14
180
0.78
0.36
1.9
2.7
921.00
824.79
e6/l
—
8
75
17
213
0.80
0.36
1.4
1.6
—
—
—
0
0
9
70
1.29
0.36
1.1
1.4
—
—
—
0
0
104
955
1.09
0.36
1.8
1.6
7.31
7.53
mmol/l
0.44
67
571
24
198
1.21
0.36
3.0
2.5
58.06
55.95
%
0.17
17
130
201
1896
1.06
0.36
1.4
1.3
219.59
233.55
miu/ml
0.22
98
958
12
90
1.33
0.35
1.1
1.2
—
—
—
0
0
12
90
1.33
0.35
1.1
1.2
95.00
96.36
%
0.06
12
90
74
669
1.11
0.35
1.1
1.1
—
—
—
0
0
105
967
1.09
0.35
2.1
1.9
—
—
—
0
0
10
73
1.37
0.34
5.4
4.6
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
50
443
1.13
0.34
3.5
3.7
0.39
0.36
u/ml
0.29
27
251
336
3224
1.05
0.33
1.5
1.5
—
—
—
0
0
22
182
1.21
0.33
1.1
1.1
—
—
—
0
0
152
1426
1.07
0.33
1.6
1.5
—
—
—
0
0
441
4260
1.04
0.32
2.5
2.5
2.43
2.43
mmol/l
0.68
381
3717
12
92
1.31
0.31
1.0
1.3
—
—
—
0
0
337
3240
1.04
0.31
1.5
1.5
—
—
—
0
0
57
513
1.11
0.31
1.5
1.5
10.96
10.18
mmol/l
—
8
42
163
1537
1.06
0.31
3.8
3.0
1.54
1.83
mmol/l
0.44
131
1267
42
371
1.13
0.30
1.3
1.4
—
—
—
0
0
41
362
1.13
0.30
1.3
1.4
—
—
—
0
0
76
696
1.09
0.30
1.1
1.1
1.35
5.18
u/ml
2.02
28
267
62
563
1.10
0.29
1.1
1.1
0.05
0.39
u/ml
0.66
14
117
337
3247
1.04
0.29
1.5
1.5
—
—
—
0
0
8
107
0.75
0.29
1.0
1.0
—
—
—
0
0
23
270
0.85
0.28
1.4
1.5
—
—
—
0
0
41
364
1.13
0.28
1.3
1.4
—
—
—
0
0
13
103
1.26
0.28
1.0
5.2
—
59.85
—
0
13
41
365
1.12
0.27
1.3
1.4
—
—
—
0
0
8
64
1.25
0.27
1.1
1.1
—
—
—
0
0
62
566
1.10
0.27
1.2
1.3
—
—
—
0
0
14
172
0.81
0.27
1.2
1.3
—
—
—
0
0
336
3245
1.04
0.26
1.5
1.5
—
—
—
0
0
62
568
1.09
0.26
1.1
1.2
—
—
—
0
0
42
377
1.12
0.25
1.3
1.4
—
—
—
0
0
53
581
0.91
0.25
1.1
1.2
—
—
—
0
0
16
133
1.20
0.24
1.3
1.5
123.38
124.27
nmol/l
0.03
16
133
41
369
1.11
0.24
1.3
1.4
—
—
—
0
0
16
190
0.84
0.23
1.6
1.6
—
—
—
0
0
16
190
0.84
0.23
1.6
1.6
—
—
—
0
0
16
190
0.84
0.23
1.6
1.6
—
—
—
0
0
64
592
1.08
0.22
1.1
1.1
—
—
—
0
0
48
438
1.10
0.22
1.4
1.3
1.17
1.30
nmol/l
0.33
34
371
10
79
1.27
0.22
1.3
1.3
8.00
11.77
u/l
—
10
73
15
178
0.84
0.22
1.9
3.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
26.23
—
0
11
148
1549
0.95
0.21
1.2
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
0.07
—
0
5
0
13
0.00
0.21
0.0
1.0
—
0.11
—
0
5
6
48
1.25
0.20
1.0
1.0
—
—
—
0
0
9
113
0.80
0.20
1.7
1.5
—
—
—
0
0
48
442
1.09
0.19
3.8
3.9
31.85
45.02
mg/l
0.67
38
366
44
404
1.09
0.19
1.9
2.1
16.94
16.65
%
0.17
20
199
22
249
0.88
0.19
1.1
1.1
1688.55
1498.21
miu/ml
0.39
22
249
10
81
1.24
0.18
1.1
1.0
64.74
74.52
ug/l
—
10
73
12
143
0.84
0.18
2.3
1.4
1552.29
3358.25
e6/l
—
7
102
230
2227
1.04
0.18
1.5
1.4
—
—
—
0
0
7
60
1.17
0.17
1.1
1.6
—
—
—
0
0
7
60
1.17
0.17
1.1
1.1
—
—
—
0
0
7
61
1.15
0.17
1.1
1.1
—
—
—
0
0
7
61
1.15
0.17
1.6
1.6
11.24
59.38
u/l
—
7
55
22
247
0.89
0.17
1.0
1.1
0.99
1.02
u/l
—
10
100
11
131
0.84
0.17
1.2
1.2
—
—
—
0
0
30
272
1.10
0.17
1.2
1.6
—
—
—
0
0
105
1002
1.05
0.17
2.5
1.9
95.95
94.28
%
0.28
97
899
26
288
0.90
0.16
5.4
5.1
376.42
373.52
umol/l
0.03
19
241
8
71
1.13
0.16
1.1
1.0
—
—
—
0
0
68
643
1.06
0.15
1.1
1.1
1.66
3.92
u/ml
2.17
36
326
9
78
1.15
0.15
1.4
3.4
—
—
—
0
0
9
79
1.14
0.15
1.0
1.1
—
—
—
0
0
9
79
1.14
0.15
1.0
1.0
—
—
—
0
0
23
255
0.90
0.15
4.5
4.9
6.84
6.61
mmol/l
0.10
16
210
18
159
1.13
0.15
1.2
1.1
—
—
—
0
0
37
342
1.08
0.15
1.0
1.1
180.18
205.06
mg/l
1.08
31
304
9
83
1.08
0.14
1.0
1.1
—
—
—
0
0
66
625
1.06
0.14
2.7
2.0
1.07
1.80
ug/l
0.50
58
564
260
2539
1.03
0.14
3.1
2.9
34.89
40.25
u/ml
0.23
250
2453
47
442
1.06
0.13
3.9
3.9
22.46
43.21
mg/l
0.95
38
366
37
345
1.07
0.12
1.5
1.4
333.76
313.57
pmol/l
0.19
29
270
16
142
1.13
0.12
3.3
3.3
—
—
—
0
0
894
8850
1.01
0.12
3.6
3.6
0.01
0.00
estimate
0.54
406
3361
25
229
1.09
0.12
1.6
1.7
—
—
—
0
0
39
365
1.07
0.12
1.2
1.1
—
—
—
0
0
14
158
0.89
0.12
1.4
1.5
—
—
—
0
0
74
709
1.04
0.11
4.2
2.7
25.06
24.83
mmol/l
0.30
65
660
11
126
0.87
0.11
2.5
1.4
4733.00
66579.70
e6/l
—
5
71
11
126
0.87
0.11
1.1
1.2
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
15
167
0.90
0.10
1.3
1.1
—
—
—
0
0
196
2004
0.98
0.10
9.7
6.6
0.69
0.87
mmol/l
0.25
157
1544
14
125
1.12
0.10
1.6
1.7
—
—
—
0
0
14
125
1.12
0.10
1.6
1.7
—
—
—
0
0
14
125
1.12
0.10
1.6
1.7
—
—
—
0
0
14
125
1.12
0.10
1.6
1.7
—
—
—
0
0
14
156
0.90
0.10
1.1
1.0
—
—
—
0
0
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
242
2376
1.02
0.09
1.6
1.5
—
—
—
0
0
40
421
0.95
0.09
1.1
1.2
—
—
—
0
0
11
97
1.13
0.09
1.0
1.1
—
—
—
0
0
479
4736
1.01
0.09
1.7
1.8
—
—
—
0
0
78
755
1.03
0.08
1.1
1.2
3.62
3.61
mmol/l
0.03
72
710
6
71
0.84
0.07
1.3
2.7
18.08
15.37
umol/l
—
6
71
6
70
0.86
0.07
1.2
1.3
—
—
—
0
0
8
75
1.07
0.07
1.1
1.1
—
—
—
0
0
8
75
1.07
0.07
1.1
1.1
—
—
—
0
0
13
143
0.91
0.07
1.2
1.5
12.02
14.05
pmol/l
1.23
13
113
37
353
1.05
0.07
1.1
1.2
43.03
35.48
mg/l
0.25
28
296
14
153
0.91
0.07
2.2
1.4
37.14
35.39
g/l
0.22
14
140
7
84
0.83
0.07
1.1
1.3
—
—
—
0
0
9
84
1.07
0.07
1.2
1.5
8.34
8.09
ug/l
—
9
84
347
3431
1.01
0.07
1.6
1.5
—
—
—
0
0
58
600
0.97
0.07
3.4
3.4
30.72
21.43
mg/l
0.88
36
359
46
442
1.04
0.07
2.4
2.2
0.82
0.82
nmol/l
0.01
37
382
358
3543
1.01
0.06
1.5
1.6
—
—
—
0
0
22
207
1.06
0.06
1.6
2.2
31.27
32.11
pg
0.29
22
207
31
296
1.05
0.05
1.1
1.1
1.08
1.04
ratio
0.52
13
105
20
188
1.06
0.05
2.0
1.3
4818.21
85814.74
e6/l
1.10
14
125
103
1050
0.98
0.05
1.3
1.4
0.38
0.52
nmol/l
1.63
83
846
64
657
0.97
0.05
1.3
1.3
—
—
—
0
0
11
100
1.10
0.05
1.2
1.3
—
—
—
0
0
11
100
1.10
0.05
1.2
1.3
—
—
—
0
0
43
416
1.03
0.05
3.2
4.3
34.23
92.21
u/ml
—
9
133
1048
10442
1.01
0.04
1.5
1.5
—
—
—
0
0
175
1770
0.99
0.04
10.4
6.9
95.86
96.39
%
0.41
168
1710
18
170
1.06
0.04
1.3
1.4
74.25
72.98
%
0.16
18
163
1288
12850
1.00
0.03
3.6
3.4
—
—
—
0
0
35
340
1.03
0.03
1.1
1.2
—
—
—
0
0
73
742
0.98
0.03
1.2
1.3
3.40
25.27
e6/l
3.32
52
565
34
332
1.02
0.01
1.0
1.1
—
—
—
0
0
1640
16417
1.00
0.01
4.2
3.9
—
—
—
0
0
91
918
0.99
0.01
1.2
1.1
—
—
—
0
0
74
747
0.99
0.01
1.8
1.9
—
—
—
0
0
107
1063
1.01
0.00
1.4
1.4
27.79
24.78
u/l
0.41
87
883
21
204
1.03
0.00
1.4
1.6
1.02
1.32
promille
0.43
15
144
10
95
1.05
0.00
12.7
13.4
1423.10
1326.15
nmol/l
—
10
89
24
242
0.99
0.00
1.2
1.3
—
68.00
—
0
14
13
125
1.04
0.00
2.5
1.7
—
—
—
0
0
14
135
1.04
0.00
1.5
1.3
5.78
6.48
mmol/l
0.85
14
128
43
428
1.00
0.00
4.5
7.5
105.18
105.33
mmol/l
0.06
38
383
74
742
1.00
0.00
1.2
1.4
1043.83
1964.17
e6/l
0.32
58
609
15
149
1.01
0.00
1.5
1.5
—
—
—
0
0
27
271
1.00
0.00
1.8
1.9
—
—
—
0
0
12
124
0.97
0.00
1.2
1.2
—
—
—
0
0
85
849
1.00
0.00
1.1
1.3
440.17
468.30
mg/l
0.25
78
811
10
96
1.04
0.00
1.8
1.9
—
—
—
0
0
10
96
1.04
0.00
1.8
1.9
—
—
—
0
0
10
96
1.04
0.00
1.8
1.9
—
—
—
0
0
233
2329
1.00
0.00
1.4
1.6
—
—
—
0
0
229
2287
1.00
0.00
1.4
1.5
—
—
—
0
0
200
2003
1.00
0.00
9.6
6.5
5.06
5.02
kpa
0.19
192
1926
200
2003
1.00
0.00
9.6
6.5
13.49
13.58
kpa
0.07
192
1922
92
923
1.00
0.00
1.2
1.1
—
—
—
0
0
16
163
0.98
0.00
1.3
1.4
1370.69
404.38
mu/l
0.39
16
156
7
78
0.90
0.00
1.1
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
4.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
2.80
—
0
5
5
58
0.86
0.00
1.2
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
5
58
0.86
0.00
4.4
2.3
109.20
146.72
nmol/l
—
5
50
25
250
1.00
0.00
1.4
1.4
—
—
—
0
0
5
51
0.98
0.00
1.6
1.2
79.80
84.45
ng/l
—
5
51
9
91
0.99
0.00
1.1
1.9
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
1.14
—
0
5
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
11
110
1.00
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
9
92
0.98
0.00
7.4
9.8
854.78
702.98
nmol/l
—
9
87
0
5
0.00
0.00
0.0
1.0
—
87.60
—
0
5
12
120
1.00
0.00
1.2
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint O15_ICP_WIDE_EXMORE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| O15_ICP_WIDE_EXMORE | 0.645 [0.51, 0.82] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.15 |
During the follow-up period (1.1.1998 — 31.12.2019), 78 out of 13316 females with O15_ICP_WIDE_EXMORE died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have O15_ICP_WIDE_EXMORE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.056% | No data |
| 5 | 0.347% | No data |
| 10 | 0.859% | No data |
| 15 | 1.645% | No data |
| 20 | 2.956% | No data |
Relationships between endpoints
↥Index endpoint: O15_ICP_WIDE_EXMORE – Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8, excluding more controls
GWS hits: 29
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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