No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditionsNone |
293373 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
3612 |
4. Check minimum number of eventsNone |
3612 |
5. Include endpointsNone |
3612 |
6. Filter based on genotype QC (FinnGen only) |
3612 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF5
- Parent code in ICD-10
- O26
- Name in latin
- Morbositates hepatis in graviditate, intra labores et/sive in puerperio
Similar endpoints
↥List of similar endpoints to
Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8
based on the number of shared cases.
Similar with more cases:
- Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8, excluding more controls
- Pregnancy, childbirth and the puerperium
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 23532 | 23532 | - |
| Only index persons | 23124 | 23124 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.67 | 0.67 | - |
| Only index persons | 0.85 | 0.85 | - |
| Median age at first event (years) | |||
| Whole population | - | 29.44 | - |
| Only index persons | - | 29.44 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3612 | 3612 | - |
| Unadjusted period prevalence (%) | 1.23 | 1.23 | - |
| Median age at first event (years) | 29.60 | 29.60 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 3252
- Matched controls
- 32519
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A05AA02
ATC
ursodeoxycholic acid; oral
91.7
323.0
809
117
63900
ICD-8 Finland
Other toxaemias of pregnancy and the puerperium, Pruritus
+∞
323.0
569
*
6467A
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Liver disorders in pregnancy[HEPATOSIS GRAVIDARUM]
+∞
323.0
680
*
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
16384.0
323.0
2068
*
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.3
82.7
1040
5599
O80.8
ICD-10 Finland
Other single spontaneous delivery
3.2
63.8
377
1298
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.9
63.7
1388
9118
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2.4
63.1
636
3011
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
2.4
60.1
585
2716
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.1
59.8
370
1313
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
2.0
57.2
979
5816
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
2.4
51.6
481
2168
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
2.2
51.1
575
2842
63998
ICD-8 Finland
Other toxaemias of pregnancy and the puerperium, Alia definitae
22.0
48.4
71
33
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
3.9
46.8
206
560
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.3
46.5
482
2281
W84
ICPC
Pregnancy high risk
3.0
45.5
276
960
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.1
43.6
564
2945
Z39.2
ICD-10 Finland
Routine postpartum follow-up
1.8
39.9
778
4735
SPAT1380
SPAT
Postpartum check-up
2.0
37.2
581
3253
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.6
36.6
1432
10642
SPAT1379
SPAT
Health check-up of pregnant person
1.9
36.0
652
3847
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
1.9
35.9
628
3660
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
3.9
35.6
154
412
SPAT1197
SPAT
Extensive health check-up of expecting family
1.8
34.1
738
4610
O30.0
ICD-10 Finland
Twin pregnancy
3.8
33.5
149
409
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
1.7
33.0
824
5370
XMA22
NOMESCO Finland
General examination of pregnant woman
2.1
29.0
367
1877
W78
ICPC
Pregnancy
1.7
28.5
789
5262
63901
ICD-8 Finland
Other toxaemias of pregnancy and the puerperium, Interus gravis
+∞
28.2
27
*
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
2.1
28.1
361
1857
Z32.1
ICD-10 Finland
Pregnancy confirmed
1.8
27.0
556
3387
O60
ICD-10 Finland
Preterm labour and delivery
2.7
25.7
180
683
63909
ICD-8 Finland
Other toxaemias of pregnancy and the puerperium, Necrosis acuta et subacuta hepatis
+∞
25.0
24
*
MAC96
NOMESCO Finland
Other induction or advancement of labour
2.6
24.6
182
714
MAX99
NOMESCO Finland
Assistance to normal delivery
1.7
24.4
529
3266
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
2.3
23.7
221
979
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
2.3
22.2
211
947
O99.80
ICD-10 Finland
The fear of childbirth
2.0
22.1
293
1520
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
3.1
21.8
124
412
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
4.2
21.5
82
198
WX307
NOMESCO Finland
Obstetric epidural analgesia
1.7
21.1
447
2733
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
2.0
21.0
268
1370
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
1.8
20.8
383
2237
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.7
20.7
489
3084
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
1.6
20.6
580
3841
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
1.7
20.5
461
2864
MAA00
NOMESCO Finland
Amniocentesis
2.5
19.8
153
618
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
1.6
18.9
538
3565
5742A
ICD-9 Finland
Cholelithiasis, Calculus of gallbladder without mention of cholecystitis[CHOLECYSTOLITHIASIS SINE CHOLECYSTITIDE,SINE OBSTR]
3.7
18.0
80
222
O82.0
ICD-10 Finland
Delivery by elective caesarean section
1.9
17.6
255
1370
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
1.8
17.1
315
1839
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
2.6
17.0
129
517
SPAT1196
SPAT
Monitoring of normal pregnancy
1.7
16.1
381
2397
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
3.2
16.0
84
267
8811
FHL
Cesarean section
1.9
15.9
254
1410
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
3.5
15.0
69
198
W29
ICPC
Pregnancy symptom/complaint other
2.3
15.0
145
658
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
14.4
1172
9535
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
1.9
13.5
210
1156
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
2.6
13.5
100
397
6510B
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, SYNNYTYKSEN AIKANA]
4.9
13.4
43
89
K76.9
ICD-10 Finland
Liver disease, unspecified
4.0
12.9
51
130
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
2.7
12.7
85
320
W85
ICPC
Gestational diabetes
1.8
12.2
197
1102
L29.9
ICD-10 Finland
Pruritus, unspecified
2.6
12.1
87
339
O61.0
ICD-10 Finland
Failed medical induction of labour
2.9
11.5
69
243
Z37.0
ICD-10 Finland
Single live birth
1.5
11.5
487
3506
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
2.3
11.3
104
462
O30.00
ICD-10 Finland
Twin pregnancy with separate amniotic and chorionic sacs
5.8
11.3
31
54
A10BX01
ATC
guar gum; systemic
2.8
11.2
71
259
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
2.3
11.2
106
479
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
3.9
11.1
45
118
W90
ICPC
Uncompl labour/delivery livebirth
1.7
11.1
219
1306
O21.0
ICD-10 Finland
Mild hyperemesis gravidarum
3.1
11.0
60
199
W92
ICPC
Compl labour/ delivery livebirth
2.2
10.9
111
518
6663
FHL
Cholecystectomy and cholangiography
3.6
10.8
47
131
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
1.8
10.7
190
1097
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
1.8
10.6
174
976
MA3AE
NOMESCO Finland
Combined first trimester screening
1.7
10.5
203
1202
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
1.9
10.3
147
788
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
10.2
1233
10469
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
1.6
10.2
248
1568
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
10.1
480
3525
O98.4
ICD-10 Finland
Viral hepatitis complicating pregnancy, childbirth and the puerperium
11.3
10.0
18
16
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
10.0
306
2047
SPAT1200
SPAT
Guidance for breast-feeding and breast care
1.9
10.0
138
732
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
2.2
9.9
93
420
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
2.3
9.8
89
396
WX320
NOMESCO Finland
Spinalanesthesy
1.4
9.7
554
4209
O84.2
ICD-10 Finland
Multiple delivery, all by caesarean section
3.9
9.6
38
99
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
2.7
9.5
62
233
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
2.8
9.4
59
214
6467X
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Liver disorders in pregnancy[HEPATOPATHIA ALIA GRAVIDARUM]
+∞
9.4
9
*
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
1.7
9.4
200
1223
O26.0
ICD-10 Finland
Excessive weight gain in pregnancy
8.7
9.3
19
22
K83.0
ICD-10 Finland
Cholangitis
4.2
9.2
33
79
O20.0
ICD-10 Finland
Threatened abortion
1.9
9.1
130
699
6510A
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, RASKAUDEN AIKANA]
4.8
9.1
29
61
V230A
ICD-9 Finland
Supervision of high-risk pregnancy, Pregnancy with history of infertility
2.8
9.1
57
207
S02
ICPC
Pruritus
2.1
8.9
100
490
B18.2
ICD-10 Finland
Chronic viral hepatitis C
3.7
8.6
36
99
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
2.6
8.6
60
235
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
2.6
8.5
60
236
63902
ICD-8 Finland
NA
+∞
8.3
8
*
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
8.5
8.3
17
20
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
8.2
897
7475
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
1.8
8.1
138
788
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.4
8.1
335
2397
P01AB01
ATC
metronidazole; oral, rectal
1.2
8.1
1284
11184
O26.9
ICD-10 Finland
Pregnancy-related condition, unspecified
3.4
8.0
37
111
L04AX01
ATC
azathioprine; systemic
1.9
8.0
114
614
SPAT1263
SPAT
Sampling
1.2
8.0
1203
10408
Z39.1
ICD-10 Finland
Care and examination of lactating mother
1.9
7.8
103
539
O72.0
ICD-10 Finland
Third-stage haemorrhage
1.9
7.8
101
526
6488A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Abnormal glucose tolerance
2.3
7.8
65
280
J01DB01
ATC
cefalexin; oral
1.3
7.8
2528
23808
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
4.2
7.7
27
64
SPAT1357
SPAT
Monitoring of problem during pregnancy
1.8
7.6
135
782
G03AC03
ATC
levonorgestrel; systemic
1.4
7.6
466
3572
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
7.5
825
6866
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
1.7
7.5
148
886
K80.1
ICD-10 Finland
Calculus of gallbladder with other cholecystitis
2.3
7.4
62
267
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
1.7
7.4
135
790
Y6099
ICD-8 Finland
Prenatal care and observation
1.7
7.3
131
762
A07EA06
ATC
budesonide; oral, local oral
2.0
7.3
90
459
G03DA04
ATC
progesterone; systemic, rectal, vaginal
1.7
7.3
148
893
A02BC01
ATC
omeprazole; systemic
1.3
7.3
662
5372
Z30.2
ICD-10 Finland
Sterilization
1.4
7.2
406
3069
B04AD01
ATC
NA
20.1
7.1
10
5
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
1.9
7.1
105
575
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
2.0
7.1
86
436
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
1.8
7.0
108
599
O02.1
ICD-10 Finland
Missed abortion
1.5
6.9
240
1660
SPAT1246
SPAT
Screening of depression or other psychiatric problem
1.6
6.8
177
1143
1413
FHL
Laparoscopy and other therapeutic procedure
1.9
6.8
88
459
WX002
NOMESCO Finland
Sedation and analgesia
1.4
6.7
399
3038
O26.5
ICD-10 Finland
Maternal hypotension syndrome
16.7
6.7
10
6
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
2.9
6.7
39
137
6440A
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS IMMINENS]
2.0
6.7
77
384
O36.9
ICD-10 Finland
Maternal care for fetal problem, unspecified
2.5
6.7
48
193
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
6.6
1822
16669
O85
ICD-10 Finland
Puerperal sepsis
2.4
6.6
50
206
K50.9
ICD-10 Finland
Crohn disease, unspecified
2.5
6.6
47
188
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
1.3
6.6
570
4591
WX306
NOMESCO Finland
Lumbar epidural anesthesy
1.4
6.5
279
2008
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
6.5
782
6564
G03DB01
ATC
dydrogesterone; oral
1.3
6.5
577
4663
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.3
6.5
446
3480
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.5
6.5
218
1498
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
3.4
6.4
28
82
W03
ICPC
Antepartum bleeding
2.7
6.4
39
144
O61.8
ICD-10 Finland
Other failed induction of labour
4.4
6.3
21
48
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
4.2
6.3
22
53
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
5.5
6.3
17
31
57409
ICD-8 Finland
Cholelithiasis, Unspecified
3.2
6.3
30
94
6500B
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
1.3
6.3
676
5596
6480A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Diabetes mellitus
3.0
6.3
33
111
K30
ICD-10 Finland
Functional dyspepsia
1.4
6.2
282
2051
O26.7
ICD-10 Finland
Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
2.3
6.2
53
232
J01DA01
ATC
[U] cefalexin; systemic
1.2
6.2
1872
17241
O84.8
ICD-10 Finland
Other multiple delivery
4.2
6.1
21
50
O40
ICD-10 Finland
Polyhydramnios
2.2
6.1
54
243
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
1.7
6.1
111
653
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
1.8
6.1
98
552
H02AB07
ATC
prednisone; oral
1.4
6.1
331
2488
UJF92
NOMESCO Finland
Capsular endoscopy
2.2
6.0
55
249
SPAT1189
SPAT
Other ultrasound examination during pregnancy
1.6
6.0
142
897
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
810
769
13.29
307.65
6.2
1.5
10.01
4.48
umol/l
12.24
714
533
292
579
5.40
140.54
1.3
1.3
108.05
111.61
u/ml
0.29
56
130
302
630
5.14
137.15
1.3
1.3
14.08
20.97
u/ml
—
5
15
293
642
4.88
125.39
1.2
1.2
203.38
270.37
u/ml
5.04
235
420
303
684
4.74
125.07
1.2
1.2
—
—
—
0
0
110
180
6.27
64.41
1.1
1.2
—
—
—
0
0
540
3161
1.83
33.46
2.4
2.4
5.98
5.95
umol/l
0.01
477
2666
1774
14063
1.51
31.91
5.2
5.4
9.58
9.60
umol/l
0.03
1678
13255
639
4044
1.70
29.96
1.6
1.5
—
—
—
0
0
193
839
2.37
26.59
1.4
1.2
72.00
194.52
titre
0.93
15
73
1319
10223
1.46
24.37
3.5
3.0
33.59
29.20
u/l
2.55
1263
9779
343
1940
1.85
23.35
1.7
1.5
—
—
—
0
0
2486
21824
1.45
22.23
7.6
6.8
79.16
72.89
u/l
11.64
2348
20625
3445
32729
2.14
20.81
11.3
8.9
30.86
23.83
u/l
35.93
3375
31792
301
1731
1.81
19.33
1.9
1.8
—
—
—
0
0
427
2707
1.65
19.31
1.5
1.4
—
—
—
0
0
299
1748
1.77
18.15
1.8
1.9
1.48
1.37
g/l
0.31
273
1622
363
2264
1.67
17.43
2.4
2.7
10.45
10.36
g/l
0.19
331
2098
1086
8623
1.37
15.76
2.4
2.4
59.07
56.33
u/l
0.35
1019
7973
337
2175
1.61
14.05
1.5
1.4
—
—
—
0
0
336
2170
1.60
13.97
1.5
1.4
—
—
—
0
0
337
2183
1.60
13.83
1.5
1.4
—
—
—
0
0
336
2181
1.60
13.67
1.5
1.4
—
—
—
0
0
2288
20523
1.31
13.34
4.5
3.9
654.22
1698.44
e6/l
0.84
23
222
1574
13447
1.30
13.14
8.4
8.1
0.00
0.00
e9/l
0.53
1300
11031
242
1462
1.70
13.06
1.6
1.5
—
—
—
0
0
347
2339
1.53
11.94
1.6
1.5
—
—
—
0
0
325
2174
1.54
11.58
2.2
2.2
0.22
0.22
g/l
0.18
301
2062
1039
8504
1.31
11.54
4.7
5.6
1.05
1.08
inr
1.07
360
2796
2770
25748
1.33
11.16
4.0
3.7
—
—
—
0
0
326
2235
1.50
10.35
3.1
4.3
244.56
232.69
u/l
0.20
309
2109
884
7166
1.31
10.34
1.5
1.4
2.08
2.14
g/l
0.71
557
4559
1888
16833
1.25
10.06
3.2
2.9
64.71
71.58
ug/l
2.47
1798
15954
929
7652
1.29
9.51
3.0
2.8
34.21
82.30
e6/l
1.51
679
5708
2395
22020
1.26
9.45
3.3
2.8
40.07
34.49
u/l
3.51
2267
20981
107
558
1.95
9.42
1.6
1.5
—
—
—
0
0
56
230
2.46
8.95
1.1
1.0
315.49
298.45
mg/l
0.53
45
206
1614
14274
1.24
8.77
6.6
6.0
8.03
7.94
%
0.58
1546
13434
1606
14202
1.24
8.72
6.4
5.7
2.85
2.77
%
0.82
1525
13239
1260
10877
1.24
8.48
4.6
4.2
36.37
36.67
g/l
1.20
1173
10162
1550
13689
1.23
8.42
6.5
5.8
0.73
0.69
%
1.89
1480
12768
835
6882
1.28
8.35
4.0
3.2
99.38
98.94
%
0.23
807
6664
2449
22731
1.24
8.11
4.4
3.9
10.28
10.16
mm/h
0.20
2317
21390
844
7003
1.27
7.93
3.0
2.7
0.20
0.29
e6/l
1.19
617
5139
72
351
2.07
7.72
1.0
1.1
1.41
1.48
g/l
0.64
61
316
2856
27032
1.27
7.66
13.9
12.8
13.45
13.49
%
0.76
2821
26508
1658
14844
1.22
7.60
6.4
5.7
29.95
29.83
%
0.21
1578
13920
49
205
2.41
7.58
1.3
1.2
272.86
199.36
titre
0.25
14
47
1635
14665
1.21
7.22
6.2
5.6
56.05
56.31
%
0.45
1565
13786
107
613
1.77
7.10
1.9
1.5
9.03
10.87
iu/ml
—
6
12
1716
15481
1.21
7.08
4.2
3.9
6.20
6.30
mmol/l
1.41
1553
14029
47
203
2.33
6.81
1.1
1.1
—
—
—
0
0
768
6403
1.25
6.81
1.3
1.3
10.26
9.35
u/ml
0.17
294
2739
994
8528
1.23
6.76
1.3
1.3
1.02
1.62
u/ml
2.40
288
2485
128
782
1.66
6.75
2.0
1.9
1.21
1.46
g/l
2.42
110
674
1640
14790
1.20
6.63
4.2
3.7
—
—
—
0
0
3118
29970
1.30
6.52
5.3
5.1
1.69
2.02
mu/l
2.01
2951
28409
35
135
2.61
6.45
2.9
2.9
8.55
7.20
mg/l
0.53
28
103
1028
8922
1.21
6.13
1.7
1.7
—
—
—
0
0
104
620
1.70
6.05
1.8
1.6
7.31
7.57
mmol/l
0.54
67
384
500
4017
1.28
5.99
2.1
2.2
14.41
14.16
umol/l
0.33
466
3721
148
967
1.55
5.96
1.2
1.2
—
—
—
0
0
112
685
1.66
5.93
4.3
3.3
780.16
350.41
u/ml
0.35
97
588
1725
15729
1.19
5.90
6.3
5.7
1.93
1.97
e9/l
0.79
1574
14156
1732
15805
1.18
5.85
6.4
5.9
0.18
0.18
e9/l
0.36
1577
14181
383
2982
1.32
5.80
2.6
2.2
6722.92
5988.01
u/l
0.17
168
1224
785
6665
1.23
5.79
1.3
1.3
25.61
28.67
iu/ml
0.29
235
2113
642
5349
1.24
5.64
2.5
2.3
9.28
8.48
e6/l
0.20
546
4637
471
3790
1.28
5.56
2.6
2.5
4.87
4.55
e6/l
0.15
238
1892
823
7052
1.22
5.51
2.3
2.1
2.56
2.75
mg/l
1.83
727
6052
76
426
1.80
5.51
1.3
1.2
—
—
—
0
0
344
2659
1.32
5.49
2.5
2.2
35.34
36.36
u/l
0.11
312
2264
1682
15381
1.18
5.36
3.5
3.3
0.00
0.00
estimate
0.88
395
2900
2792
26693
1.20
5.02
4.7
4.4
14.38
14.37
pmol/l
0.07
2608
25119
777
6677
1.21
5.00
2.2
2.1
615.94
2659.10
umol/l
4.89
683
5923
31
129
2.42
4.96
1.2
1.2
—
—
—
0
0
1685
15478
1.17
4.92
4.9
4.5
0.00
0.00
estimate
0.80
405
2983
1696
15602
1.16
4.82
3.6
3.3
0.00
0.01
estimate
1.80
411
2949
443
3608
1.26
4.73
2.2
2.2
2.48
2.47
g/l
0.19
407
3341
403
3257
1.27
4.59
2.2
2.3
23.41
23.51
%
0.05
347
2797
3207
31182
1.25
4.39
11.8
10.6
17.16
18.65
mg/l
2.11
2504
24026
1451
13259
1.16
4.37
2.4
2.3
76.94
75.67
nmol/l
1.03
1347
12363
129
881
1.48
4.32
2.5
2.5
3.94
3.58
g/l
1.84
118
823
119
802
1.50
4.26
2.4
1.7
531.43
448.24
titre
—
7
34
46
240
1.93
4.25
1.0
1.1
—
—
—
0
0
813
7112
1.18
4.23
1.9
1.7
1.03
0.86
mg/l
1.00
600
5296
807
7059
1.18
4.20
2.0
1.9
—
—
—
0
0
3314
32372
1.29
4.20
12.1
11.3
66.02
66.37
umol/l
0.55
3309
32360
170
1232
1.40
4.16
1.4
1.3
—
—
—
0
0
562
4766
1.21
4.11
3.0
2.3
97.07
97.34
ug/g
0.01
451
3743
3122
30305
1.22
4.11
10.9
10.4
139.69
139.65
mmol/l
0.40
3050
29500
2962
28609
1.20
4.10
10.0
9.1
90.29
90.00
ml/min/173m2
0.34
2475
23424
3132
30412
1.22
4.10
11.0
10.5
3.89
3.90
mmol/l
2.19
3061
29526
229
2955
0.76
3.93
5.1
5.0
—
—
—
0
0
1357
12413
1.15
3.91
5.4
5.5
1.22
1.22
mmol/l
1.18
1159
10487
1865
17444
1.14
3.86
8.4
8.6
3.83
3.90
e9/l
0.86
1660
15410
488
4118
1.21
3.75
2.5
2.4
2.25
1.08
e6/l
0.58
254
2208
1123
10210
1.14
3.44
1.8
1.8
102.45
99.68
pmol/l
1.08
569
5341
29
140
2.08
3.37
1.2
1.2
—
—
—
0
0
46
262
1.77
3.30
1.0
1.1
8.09
9.33
iu/ml
0.13
12
74
400
3363
1.21
3.21
2.4
2.0
29.01
29.16
s
0.20
383
3252
806
7190
1.16
3.20
1.9
2.0
133.42
136.44
u/l
0.07
772
6811
48
280
1.72
3.19
1.3
1.2
47.05
59.71
u/l
1.13
38
195
47
273
1.73
3.17
1.1
1.2
—
—
—
0
0
3539
35024
1.52
3.15
17.8
16.0
266.33
269.12
e9/l
2.00
3484
34362
32
166
1.94
3.09
1.9
1.5
1.53
4.48
u/l
2.14
19
86
94
649
1.46
3.08
1.7
1.4
6.53
6.95
mmol/l
0.83
63
463
151
1133
1.35
3.07
1.4
1.4
—
—
—
0
0
201
1578
1.29
2.97
1.2
1.3
0.29
1.10
u/ml
2.03
16
139
1203
11080
1.13
2.93
5.1
4.9
1.22
1.22
mmol/l
1.14
1130
10096
3539
35049
1.48
2.84
17.7
16.0
4.44
4.45
e12/l
0.80
3480
34342
309
2568
1.22
2.80
1.3
1.3
196.80
155.42
u/ml
0.23
291
2391
3539
35053
1.48
2.79
17.8
16.0
6.61
6.63
e9/l
0.14
3481
34320
38
218
1.75
2.72
1.4
1.4
—
—
—
0
0
3539
35061
1.46
2.69
17.9
16.1
132.19
133.12
g/l
5.87
3515
34727
323
2718
1.21
2.60
2.7
3.4
4.56
4.52
pmol/l
0.32
297
2445
894
8141
1.13
2.57
3.6
3.6
0.01
0.00
estimate
0.43
406
2968
88
629
1.41
2.46
1.2
1.2
—
—
—
0
0
611
5446
1.15
2.44
1.4
1.4
21.86
21.43
nmol/l
0.29
528
4803
2968
28961
1.14
2.36
3.7
3.7
5.60
5.63
mmol/l
0.86
2774
27143
354
3033
1.19
2.36
1.9
2.1
380.51
373.71
nmol/l
0.27
332
2800
284
2387
1.21
2.34
2.5
2.6
—
—
—
0
0
61
412
1.49
2.31
2.0
1.7
36.00
27.05
iu/ml
—
5
21
47
300
1.57
2.30
1.2
1.1
—
58.03
—
0
6
9
218
0.41
2.29
7.4
12.3
854.78
865.34
nmol/l
—
9
208
136
1055
1.30
2.27
1.7
2.1
3.25
4.34
iu/l
1.51
47
429
159
1259
1.28
2.27
1.9
2.1
40.10
39.08
u/l
0.28
146
1160
1288
12046
1.11
2.27
3.6
3.3
—
—
—
0
0
806
7359
1.12
2.20
1.6
1.6
1.25
1.35
mmol/l
2.13
706
6363
117
898
1.31
2.13
1.3
1.3
72.23
38.00
u/ml
—
9
91
292
2488
1.19
2.10
2.3
2.4
19.54
22.14
au/ml
0.21
12
190
57
390
1.47
2.06
1.5
1.4
10.96
11.69
mmol/l
—
8
50
44
286
1.55
2.03
1.2
1.1
—
—
—
0
0
87
645
1.36
2.02
1.2
1.1
12.11
11.83
au/ml
0.02
12
39
80
1077
0.74
1.98
1.3
1.3
2.93
3.80
ug/l
1.06
74
990
163
1320
1.25
1.97
1.7
1.7
—
—
—
0
0
21
112
1.88
1.96
1.0
1.1
—
—
—
0
0
84
623
1.36
1.95
3.6
3.6
57.35
57.13
%
0.06
84
623
147
1179
1.26
1.93
2.0
2.1
—
—
—
0
0
127
1002
1.28
1.91
1.3
1.3
6.34
9.19
u/ml
0.35
16
169
422
3738
1.15
1.87
3.1
3.2
0.83
0.82
mmol/l
1.33
398
3500
46
309
1.49
1.85
2.0
1.6
—
—
—
0
0
11
46
2.40
1.85
1.2
1.2
—
—
—
0
0
10
223
0.45
1.83
12.7
18.0
1423.10
5845.68
nmol/l
—
10
213
5
12
4.17
1.82
1.0
1.0
—
—
—
0
0
922
8563
1.10
1.81
2.6
2.7
25.88
29.98
ng/l
0.21
385
3937
9
35
2.58
1.80
1.0
1.3
—
—
—
0
0
124
989
1.26
1.74
1.3
1.3
6.51
5.79
u/ml
0.06
11
104
71
524
1.36
1.74
1.8
1.7
16640.50
8268.19
e6/l
0.63
52
386
76
572
1.34
1.65
1.5
1.4
—
—
—
0
0
462
4155
1.13
1.64
3.0
2.9
284.90
319.85
ng/l
0.11
255
2291
53
377
1.41
1.62
1.1
1.2
—
—
—
0
0
48
336
1.43
1.61
2.2
2.6
1.62
1.42
%
0.20
41
260
134
1090
1.24
1.61
1.4
1.5
—
—
—
0
0
518
4698
1.12
1.60
2.5
2.6
669.35
602.40
ng/l
0.14
419
3834
384
3420
1.14
1.59
1.2
1.2
179.40
157.62
iu/ml
0.42
152
1372
156
1295
1.21
1.55
2.3
2.6
72.20
104.53
ng/l
2.25
137
1149
129
1050
1.24
1.55
1.2
1.2
—
—
—
0
0
185
1562
1.19
1.54
2.2
2.6
66.86
67.34
g/l
0.43
171
1446
43
298
1.45
1.53
1.3
1.2
—
—
—
0
0
10
44
2.28
1.53
1.2
1.2
—
—
—
0
0
43
299
1.44
1.51
1.3
1.2
—
—
—
0
0
13
65
2.00
1.48
1.1
1.2
—
—
—
0
0
43
301
1.43
1.46
1.3
1.2
—
—
—
0
0
43
301
1.43
1.46
1.3
1.2
—
—
—
0
0
43
301
1.43
1.46
1.3
1.2
—
—
—
0
0
10
202
0.49
1.45
1.9
2.4
—
—
—
0
0
58
429
1.36
1.44
2.0
1.3
—
106.67
—
0
6
83
649
1.29
1.42
2.3
2.3
9.83
10.19
g/l
0.47
77
568
135
1117
1.22
1.41
1.3
1.3
85.86
39.94
u/ml
—
5
81
2687
26296
1.09
1.37
4.6
4.4
37.49
37.74
mmol/mol
0.94
2536
24815
25
158
1.59
1.37
1.2
1.1
96.27
93.45
%
0.26
11
64
670
6215
1.10
1.35
4.4
3.9
9.34
9.02
mg/mmol
0.07
408
3750
96
1189
0.80
1.35
1.3
1.2
12.36
12.12
u/l
0.06
80
990
44
315
1.40
1.35
2.9
2.4
62.87
62.30
%
0.06
44
315
239
2090
1.15
1.33
2.0
2.5
1.64
1.74
%
1.03
210
1851
66
506
1.31
1.32
3.5
5.1
123.71
501.93
iu/ml
—
7
59
39
545
0.71
1.31
1.4
1.5
—
—
—
0
0
28
416
0.67
1.31
1.4
1.4
—
—
—
0
0
181
1553
1.17
1.29
7.6
7.5
7.82
7.52
mmol/l
0.27
173
1500
22
137
1.61
1.29
1.3
1.7
—
—
—
0
0
18
107
1.69
1.25
31.3
25.1
111.50
100.45
ug/l
0.29
18
89
35
244
1.44
1.25
2.0
1.3
—
—
—
0
0
6
25
2.40
1.24
1.0
1.2
—
—
—
0
0
60
462
1.30
1.19
1.2
1.2
—
—
—
0
0
60
462
1.30
1.19
1.2
1.2
—
—
—
0
0
231
2037
1.14
1.17
3.2
3.2
1.23
1.23
mmol/l
0.90
211
1761
258
2292
1.14
1.17
10.9
13.5
1.08
1.12
inr
0.34
51
393
201
2294
0.87
1.16
1.4
1.5
—
—
—
0
0
751
7053
1.08
1.15
3.7
3.1
7.28
7.25
mmol/l
0.07
652
6083
15
87
1.73
1.15
1.4
6.9
11863.60
62.43
mg/l
—
10
58
130
1098
1.19
1.14
2.3
2.0
0.23
0.23
g/l
0.15
125
1030
1048
9967
1.07
1.14
1.5
1.5
—
—
—
0
0
3034
29908
1.09
1.14
12.9
11.3
39.28
39.52
%
1.19
2473
24245
592
5513
1.09
1.11
1.6
1.6
15238528.58
39609181.86
pmol/l
0.78
525
4754
23
151
1.53
1.11
1.2
1.1
101.36
96.69
%
0.37
11
61
639
5970
1.09
1.11
3.6
3.2
381.71
473.11
mg/l
0.19
391
3514
22
143
1.54
1.11
1.1
1.2
—
—
—
0
0
71
565
1.26
1.11
2.3
2.1
39.02
38.67
g/l
0.20
66
511
78
628
1.25
1.10
2.9
2.2
0.40
0.55
g/l
0.26
73
566
343
3114
1.11
1.09
3.7
3.7
33.20
32.78
%
0.32
256
2278
120
1012
1.19
1.09
1.5
1.6
—
—
—
0
0
744
7005
1.08
1.07
2.1
2.1
—
—
—
0
0
135
1153
1.18
1.06
2.6
2.4
0.31
0.25
e6/l
0.23
128
1092
72
579
1.25
1.04
1.4
1.2
2.29
4.45
u/ml
2.57
28
227
17
265
0.64
1.04
1.5
2.1
13.14
12.78
%
—
7
136
41
543
0.75
1.03
1.5
1.5
—
—
—
0
0
5
107
0.47
1.01
4.4
2.2
109.20
164.33
nmol/l
—
5
93
87
718
1.22
1.00
2.2
2.2
7.29
7.34
g/l
0.10
74
566
87
718
1.22
1.00
2.2
2.2
3.70
3.73
g/l
0.07
69
532
87
718
1.22
1.00
2.2
2.2
—
—
—
0
0
22
147
1.50
1.00
1.1
1.3
—
—
u/ml
—
0
0
93
1113
0.83
1.00
5.8
7.1
24.84
24.42
mmol/l
0.58
84
1031
664
6243
1.08
0.99
2.0
2.0
—
—
—
0
0
74
601
1.24
0.99
1.3
1.2
1.28
3.13
u/ml
2.40
25
189
5
23
2.18
0.98
1.2
1.0
8.16
8.07
mmol/l
—
5
23
35
467
0.75
0.95
1.5
1.4
32.56
31.69
nmol/l
0.06
28
414
29
208
1.40
0.94
1.2
1.2
—
—
—
0
0
230
2065
1.12
0.93
1.8
1.8
—
—
—
0
0
34
252
1.35
0.92
1.1
1.2
—
—
—
0
0
19
126
1.51
0.91
1.2
1.1
—
—
—
0
0
191
1702
1.13
0.88
1.5
1.6
—
—
—
0
0
22
152
1.45
0.88
1.3
1.6
0.77
2.96
u/field
1.76
13
106
26
358
0.72
0.87
5.4
5.6
376.42
378.34
umol/l
0.02
19
307
10
56
1.79
0.87
5.4
4.9
—
—
—
0
0
420
3901
1.09
0.87
1.7
1.7
1126.46
1189.94
nmol/l
0.84
339
3023
54
431
1.26
0.87
2.4
2.7
14.83
88.78
ug/min
3.55
37
271
122
1055
1.16
0.87
1.5
1.6
0.05
0.38
iu/ml
1.14
21
195
34
255
1.34
0.86
1.1
1.2
—
—
—
0
0
117
1010
1.16
0.85
2.2
2.0
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
28
204
1.38
0.85
2.0
1.9
127.47
120.89
%
0.21
28
196
954
9132
1.06
0.85
2.9
3.1
2.35
2.35
mmol/l
0.01
839
8229
129
1123
1.15
0.85
1.1
1.1
8.14
5.59
u/ml
0.14
18
174
377
3493
1.09
0.83
1.7
1.7
—
—
—
0
0
48
381
1.26
0.82
1.8
2.4
—
709.08
—
0
12
6
32
1.88
0.81
1.2
1.1
—
—
—
0
0
37
284
1.31
0.81
1.7
1.7
53.33
51.51
%
0.09
24
166
3043
30092
1.07
0.81
3.8
3.7
4.81
4.89
mmol/l
5.47
2903
28626
82
693
1.19
0.79
2.3
2.2
2.83
3.09
g/l
1.97
72
546
38
485
0.78
0.78
1.1
1.1
2.50
19037.49
iu/ml
—
6
127
188
1690
1.12
0.78
9.4
6.0
1.20
1.21
mmol/l
0.08
183
1630
57
466
1.23
0.77
2.9
3.3
24.67
24.71
mmol/l
0.02
48
414
361
3356
1.08
0.75
1.3
1.3
28.57
27.69
iu/l
0.19
322
2921
71
595
1.20
0.75
1.2
1.1
—
—
—
0
0
47
377
1.25
0.75
1.1
1.4
—
3728.00
—
0
5
5
25
2.00
0.72
1.2
1.1
—
—
—
0
0
9
56
1.61
0.72
1.0
1.3
—
—
—
0
0
423
3968
1.07
0.71
1.6
1.6
1.33
1.32
%
0.15
370
3582
105
916
1.15
0.70
2.1
1.8
—
—
—
0
0
20
275
0.73
0.70
1.4
1.5
—
—
—
0
0
47
381
1.24
0.70
3.5
2.9
29.34
34.55
umol/l
1.55
38
339
87
749
1.17
0.70
1.4
1.3
324.91
313.32
ug/g
0.21
43
385
93
805
1.16
0.69
2.0
2.1
10.33
10.68
mg/l
0.16
87
755
198
2176
0.90
0.69
2.3
2.3
72.83
75.28
ml/min/173m2
0.44
72
827
5
27
1.85
0.68
1.2
2.0
0.60
0.89
u/field
—
5
27
7
42
1.67
0.68
1.1
1.1
—
—
—
0
0
5
95
0.53
0.66
4.4
2.7
—
—
—
0
0
25
188
1.33
0.66
1.6
1.9
0.70
2.10
u/field
—
10
98
22
294
0.75
0.66
1.5
1.4
—
—
—
0
0
18
248
0.72
0.65
1.4
2.1
—
—
—
0
0
102
1159
0.88
0.64
15.0
8.0
94.20
94.27
%
0.03
102
1154
201
1837
1.10
0.64
1.4
1.3
219.59
238.06
miu/ml
0.31
98
948
152
1369
1.12
0.64
1.6
1.5
—
—
—
0
0
14
201
0.70
0.64
1.9
2.7
921.00
846.12
e6/l
—
8
85
29
371
0.78
0.64
1.5
1.6
—
—
—
0
0
30
381
0.79
0.63
1.1
1.1
—
—
—
0
0
261
2419
1.09
0.62
7.9
6.2
104.96
104.79
mmol/l
0.32
256
2368
43
352
1.22
0.61
1.8
1.6
—
—
—
0
0
28
357
0.78
0.61
1.6
1.5
—
—
—
0
0
298
2780
1.08
0.60
5.2
5.0
1.05
1.04
mmol/l
0.28
279
2597
108
958
1.13
0.60
1.2
1.1
2.03
1.25
u/ml
0.45
38
348
17
122
1.40
0.60
1.2
1.2
—
—
—
0
0
42
344
1.22
0.59
1.3
1.4
—
—
—
0
0
201
2184
0.92
0.58
1.5
1.4
—
—
—
0
0
159
1445
1.10
0.58
2.1
2.5
65.81
72.71
e9/l
2.09
112
1056
3065
30386
1.06
0.58
4.0
4.0
2.88
2.93
mmol/l
2.58
2897
28708
41
336
1.22
0.58
1.3
1.4
—
—
—
0
0
41
336
1.22
0.58
1.3
1.4
—
—
—
0
0
21
275
0.76
0.56
1.1
1.1
—
—
—
0
0
128
1418
0.90
0.56
2.1
2.0
—
—
—
0
0
41
338
1.22
0.56
1.3
1.4
—
—
—
0
0
56
476
1.18
0.56
1.5
2.3
131.16
130.24
g/l
0.13
44
355
10
65
1.54
0.55
1.3
1.2
8.00
12.66
u/l
—
10
58
74
644
1.15
0.55
1.1
1.1
—
—
—
0
0
13
90
1.45
0.55
1.1
1.1
—
—
—
0
0
181
1663
1.09
0.54
1.8
1.7
2.92
3.65
mg/l
0.81
135
1149
123
1108
1.11
0.54
3.4
3.0
1.81
1.63
mmol/l
0.23
80
827
103
1153
0.89
0.54
14.8
8.0
0.70
0.69
%
0.12
103
1147
30
372
0.80
0.53
1.2
1.6
—
—
—
0
0
42
350
1.20
0.52
1.3
1.4
—
—
—
0
0
14
192
0.73
0.52
1.2
1.3
—
—
—
0
0
107
960
1.12
0.52
13.8
8.2
24.02
24.19
mmol/l
0.23
102
903
6
40
1.50
0.51
1.2
1.2
—
—
—
0
0
6
40
1.50
0.51
1.2
1.2
—
—
—
0
0
35
287
1.22
0.51
1.9
1.9
17.60
26.21
mg/l
—
8
75
233
2173
1.08
0.50
1.1
1.0
—
—
—
0
0
13
92
1.41
0.50
1.7
1.3
519.84
351.16
u/l
0.40
13
87
81
716
1.13
0.50
3.3
5.3
1.75
1.66
%
0.18
75
668
236
2203
1.08
0.50
4.2
3.7
59.63
33.58
ug/l
0.25
179
1626
157
1709
0.91
0.50
11.2
7.7
119.09
120.85
g/l
0.57
150
1648
405
3850
1.06
0.50
1.6
1.6
—
—
—
0
0
41
343
1.20
0.50
1.3
1.4
—
—
—
0
0
34
279
1.22
0.50
1.3
1.3
—
—
—
0
0
28
346
0.81
0.49
1.5
1.4
—
—
—
0
0
48
408
1.18
0.49
1.1
1.1
95.81
95.35
%
0.05
48
380
27
216
1.25
0.49
1.9
1.5
48.22
41.22
%
0.39
19
120
90
803
1.12
0.48
1.1
1.1
1.74
1.42
u/ml
0.11
21
188
3019
29953
1.05
0.48
3.8
3.6
1.57
1.57
mmol/l
0.10
2874
28416
74
652
1.14
0.48
1.1
1.1
1.02
3.66
u/ml
4.69
31
239
76
671
1.14
0.48
1.4
1.6
—
—
—
0
0
104
1153
0.90
0.48
14.7
8.0
1.15
1.33
%
1.72
104
1145
72
816
0.88
0.48
1.2
1.2
—
—
—
0
0
19
244
0.78
0.47
1.5
1.6
—
—
—
0
0
17
221
0.77
0.46
1.4
1.5
—
—
—
0
0
8
118
0.68
0.45
3.6
2.2
1.17
1.05
ug/l
—
8
110
2904
28804
1.04
0.44
3.4
3.3
1.12
1.21
mmol/l
13.03
2765
27246
11
78
1.41
0.43
2.2
3.1
—
—
—
0
0
62
546
1.14
0.42
1.1
1.3
—
—
—
0
0
5
32
1.56
0.42
1.4
1.1
—
—
—
0
0
5
32
1.56
0.42
1.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
0.29
—
0
6
12
88
1.36
0.40
1.1
1.1
95.00
98.55
%
0.18
12
88
12
88
1.36
0.40
2.4
2.1
—
—
—
0
0
12
88
1.36
0.40
1.1
1.1
—
—
—
0
0
7
103
0.68
0.39
1.9
1.4
—
—
—
0
0
5
35
1.43
0.39
1.0
1.1
—
—
—
0
0
57
503
1.14
0.39
2.5
2.6
—
—
—
0
0
14
182
0.77
0.39
1.4
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
0.18
—
0
7
7
106
0.66
0.39
1.9
1.4
—
—
—
0
0
74
666
1.11
0.38
1.8
1.9
—
—
—
0
0
230
2176
1.06
0.37
1.5
1.4
—
—
—
0
0
97
889
1.09
0.36
4.5
3.7
23.93
24.27
mmol/l
0.50
84
797
217
2053
1.06
0.35
1.7
1.6
410.86
304.59
mu/l
0.34
190
1812
23
277
0.83
0.35
1.4
1.5
—
—
—
0
0
12
91
1.32
0.33
1.0
1.3
—
—
—
0
0
16
199
0.80
0.33
1.6
1.5
—
—
—
0
0
16
199
0.80
0.33
1.6
1.5
—
—
—
0
0
16
199
0.80
0.33
1.6
1.5
—
—
—
0
0
191
1805
1.06
0.33
3.4
3.3
72.99
74.10
ng/l
0.08
170
1596
6
90
0.67
0.32
1.3
2.3
18.08
15.84
umol/l
—
6
90
196
2070
0.94
0.32
9.7
6.9
0.69
0.90
mmol/l
0.31
157
1597
11
83
1.33
0.32
1.0
1.1
—
—
—
0
0
28
239
1.17
0.31
2.6
2.7
—
—
—
0
0
125
1168
1.07
0.31
3.7
3.0
5.12
5.15
kpa
0.16
113
1092
672
6549
1.03
0.30
3.7
3.6
1.02
1.02
kg/l
0.26
117
991
7
56
1.25
0.29
1.1
1.5
—
—
—
0
0
8
107
0.75
0.29
1.0
1.0
—
—
—
0
0
11
85
1.30
0.28
1.2
1.2
—
—
—
0
0
11
85
1.30
0.28
1.2
1.2
—
—
—
0
0
92
854
1.08
0.28
1.1
1.1
3.14
5.59
u/ml
1.17
42
434
35
308
1.14
0.27
1.1
1.2
—
—
—
0
0
9
117
0.77
0.27
1.7
1.4
—
—
—
0
0
31
271
1.15
0.27
1.1
1.1
1.08
1.04
ratio
0.50
13
103
62
567
1.10
0.26
1.2
1.3
—
—
—
0
0
30
262
1.15
0.26
1.2
1.6
—
—
—
0
0
24
206
1.17
0.26
3.0
2.4
58.06
55.57
%
0.21
17
134
37
329
1.13
0.26
1.0
1.1
180.18
213.81
mg/l
1.56
31
291
78
723
1.08
0.25
1.1
1.2
3.62
3.59
mmol/l
0.10
72
680
9
75
1.20
0.25
1.1
1.3
—
—
—
0
0
13
105
1.24
0.24
1.0
5.0
—
379.36
—
0
14
68
628
1.08
0.24
2.8
2.1
151.53
332.16
ug/l
0.72
58
553
76
708
1.08
0.22
1.1
1.1
1.35
3.67
u/ml
2.00
28
250
33
295
1.12
0.22
1.1
1.2
0.62
0.47
u/ml
—
9
97
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
28.00
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
64
594
1.08
0.21
1.1
1.1
—
—
—
0
0
105
993
1.06
0.21
2.5
2.0
95.95
95.31
%
0.09
97
899
126
1324
0.95
0.21
2.1
2.0
12.19
5.09
ug/l
1.18
110
1173
62
577
1.08
0.20
1.1
1.1
0.05
0.43
u/ml
0.69
14
110
6
50
1.20
0.19
1.0
1.0
—
—
—
0
0
86
811
1.06
0.19
1.1
1.1
0.81
1.05
u/ml
0.20
32
326
140
1340
1.05
0.19
3.1
2.8
4.73
4.64
kpa
0.17
134
1291
68
637
1.07
0.19
1.1
1.1
1.66
3.45
u/ml
2.03
36
334
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
15
175
0.86
0.18
1.3
1.1
—
—
—
0
0
107
1018
1.05
0.18
1.4
1.4
27.79
25.26
u/l
0.32
87
850
200
2070
0.96
0.18
9.6
6.8
5.06
5.05
kpa
0.01
192
1982
200
2070
0.96
0.18
9.6
6.8
13.49
13.54
kpa
0.04
192
1979
39
357
1.09
0.18
1.2
1.1
—
—
—
0
0
37
338
1.10
0.18
1.5
1.3
333.76
401.12
pmol/l
0.31
29
264
14
119
1.18
0.17
1.1
1.1
—
—
—
0
0
12
142
0.84
0.17
2.3
1.3
1552.29
3680.97
e6/l
—
7
100
37
339
1.09
0.17
1.1
1.1
43.03
33.54
mg/l
0.32
28
287
44
407
1.08
0.17
1.9
2.4
16.94
16.68
%
0.15
20
203
7
63
1.11
0.17
1.1
1.1
—
—
—
0
0
7
63
1.11
0.17
1.6
1.7
11.24
68.68
u/l
—
7
56
8
68
1.18
0.16
1.1
1.1
—
—
—
0
0
479
4702
1.02
0.16
1.7
1.8
—
—
—
0
0
8
72
1.11
0.16
1.1
1.1
—
—
—
0
0
9
79
1.14
0.15
1.0
1.5
—
—
—
0
0
9
79
1.14
0.15
1.0
1.5
—
—
—
0
0
34
313
1.09
0.15
1.0
1.1
—
—
—
0
0
22
242
0.91
0.13
1.0
1.1
0.99
1.04
u/l
—
10
105
15
169
0.89
0.12
1.9
2.8
—
—
—
0
0
14
123
1.14
0.12
1.6
1.7
—
—
—
0
0
14
123
1.14
0.12
1.6
1.7
—
—
—
0
0
14
123
1.14
0.12
1.6
1.7
—
—
—
0
0
14
123
1.14
0.12
1.6
1.7
—
—
—
0
0
11
127
0.87
0.12
1.1
1.2
—
—
—
0
0
12
104
1.15
0.12
1.2
1.2
—
—
—
0
0
10
85
1.18
0.12
1.1
1.0
64.74
76.52
ug/l
—
10
73
43
404
1.07
0.12
4.5
7.9
105.18
105.45
mmol/l
0.11
38
361
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
50
473
1.06
0.12
3.5
3.9
0.39
0.36
u/ml
0.29
27
262
25
271
0.92
0.11
1.4
1.3
—
—
—
0
0
16
178
0.90
0.11
1.3
1.5
1370.69
436.69
mu/l
0.38
16
170
58
554
1.05
0.10
3.4
3.6
30.73
22.20
mg/l
0.78
36
337
64
613
1.04
0.10
1.3
1.3
—
—
—
0
0
85
820
1.04
0.10
1.1
1.3
440.17
452.93
mg/l
0.10
78
786
5
46
1.09
0.09
1.6
1.2
79.80
85.04
ng/l
—
5
46
13
145
0.90
0.09
2.5
1.6
—
—
—
0
0
14
155
0.90
0.09
1.1
1.0
—
—
—
0
0
46
482
0.95
0.09
2.4
2.5
0.82
0.82
nmol/l
0.00
37
409
25
233
1.07
0.09
1.6
1.8
—
—
—
0
0
175
1786
0.98
0.08
10.4
7.4
95.86
96.28
%
0.30
168
1722
7
64
1.09
0.08
1.1
1.2
—
—
—
0
0
91
936
0.97
0.08
1.2
1.1
—
—
—
0
0
7
66
1.06
0.08
1.1
1.3
—
—
—
0
0
22
205
1.07
0.07
1.1
1.1
—
—
—
0
0
8
76
1.05
0.07
1.1
1.1
—
—
—
0
0
12
108
1.11
0.07
1.2
1.2
—
—
—
0
0
9
85
1.06
0.07
1.0
1.1
—
—
—
0
0
9
85
1.06
0.07
1.0
1.0
—
—
—
0
0
358
3619
0.99
0.07
1.5
1.7
—
—
—
0
0
9
88
1.02
0.07
1.4
3.1
—
—
—
0
0
229
2258
1.02
0.06
1.4
1.6
—
—
—
0
0
74
720
1.03
0.06
1.2
1.4
1043.83
6259.29
e6/l
0.50
58
579
233
2300
1.01
0.06
1.4
1.6
—
—
—
0
0
92
941
0.98
0.06
1.2
1.1
—
—
—
0
0
18
168
1.07
0.06
1.2
1.1
—
—
—
0
0
24
253
0.95
0.05
1.2
1.2
—
55.57
—
0
14
16
149
1.07
0.05
1.3
1.6
123.38
127.90
nmol/l
0.20
16
149
11
100
1.10
0.05
1.0
1.2
—
—
—
0
0
74
723
1.02
0.05
4.2
2.9
25.06
24.85
mmol/l
0.27
65
672
11
120
0.92
0.05
2.5
1.4
4733.00
81884.59
e6/l
—
5
68
103
1048
0.98
0.04
1.3
1.5
0.38
0.47
nmol/l
0.91
83
845
13
140
0.93
0.04
1.2
1.4
12.02
14.07
pmol/l
1.26
13
115
66
645
1.02
0.04
2.7
2.0
1.07
2.30
ug/l
0.85
58
581
48
467
1.03
0.04
1.4
1.3
1.17
1.45
nmol/l
0.75
34
382
260
2578
1.01
0.04
3.1
2.9
34.89
39.26
u/ml
0.18
250
2497
14
131
1.07
0.03
1.5
1.3
5.78
6.41
mmol/l
0.73
14
120
441
4433
0.99
0.03
2.5
2.5
2.43
2.43
mmol/l
0.28
381
3876
40
389
1.03
0.03
1.1
1.2
—
—
—
0
0
27
260
1.04
0.03
1.8
1.9
—
—
—
0
0
23
239
0.96
0.02
4.5
6.6
6.84
6.94
mmol/l
0.04
16
199
73
720
1.01
0.02
1.2
1.3
3.40
20.74
e6/l
4.06
52
547
163
1642
0.99
0.02
3.8
3.4
1.54
1.85
mmol/l
0.48
131
1356
11
103
1.07
0.02
1.2
1.1
—
—
—
0
0
47
478
0.98
0.01
3.9
3.7
22.46
46.37
mg/l
1.09
38
390
21
203
1.03
0.01
1.4
1.7
1.02
1.18
promille
0.21
15
158
166
1653
1.00
0.00
3.8
3.4
5.79
5.82
kpa
0.14
161
1597
10
98
1.02
0.00
1.8
1.8
—
—
—
0
0
10
98
1.02
0.00
1.8
1.8
—
—
—
0
0
10
98
1.02
0.00
1.8
1.8
—
—
—
0
0
15
145
1.03
0.00
1.5
1.5
—
—
—
0
0
18
185
0.97
0.00
1.3
1.5
74.25
72.61
%
0.21
18
177
43
426
1.01
0.00
3.2
4.5
34.23
73.40
u/ml
—
9
134
16
156
1.03
0.00
3.3
4.0
—
—
—
0
0
22
224
0.98
0.00
1.1
1.1
1688.55
1527.62
miu/ml
0.32
22
224
48
477
1.01
0.00
3.8
3.7
31.85
43.61
mg/l
0.62
38
391
14
143
0.98
0.00
2.2
1.4
37.14
34.76
g/l
0.32
14
131
8
83
0.96
0.00
1.1
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
9
93
0.97
0.00
1.1
2.1
—
—
—
0
0
8
83
0.96
0.00
1.1
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
2.60
—
0
5
6
64
0.94
0.00
1.2
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
4.9
—
—
—
0
0
9
91
0.99
0.00
1.2
1.5
8.34
7.95
ug/l
—
9
91
9
90
1.00
0.00
1.0
1.0
—
—
—
0
0
5
57
0.88
0.00
1.2
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
5.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
20
200
1.00
0.00
2.0
1.4
4818.21
51820.58
e6/l
0.80
14
136
0
8
0.00
0.00
0.0
3.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint O15_ICP_WIDE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| O15_ICP_WIDE | 0.645 [0.51, 0.82] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.15 |
During the follow-up period (1.1.1998 — 31.12.2019), 78 out of 13316 females with O15_ICP_WIDE died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have O15_ICP_WIDE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.056% | No data |
| 5 | 0.347% | No data |
| 10 | 0.859% | No data |
| 15 | 1.645% | No data |
| 20 | 2.956% | No data |
Relationships between endpoints
↥Index endpoint: O15_ICP_WIDE – Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8
GWS hits: 29
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data