No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleonly females |
293218 |
2. Check conditionsNone |
293218 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
3700 |
4. Check minimum number of eventsNone |
3700 |
5. Include endpointsNone |
3700 |
6. Filter based on genotype QC (FinnGen only) |
3563 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF5
- Parent code in ICD-10
- O26
- Name in latin
- Morbositates hepatis in graviditate, intra labores et/sive in puerperio
Similar endpoints
↥List of similar endpoints to
Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8
based on the number of shared cases.
Similar with more cases:
- Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8, excluding more controls
- Pregnancy, childbirth and the puerperium
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 23532 | 23532 | - |
| Only index persons | 23124 | 23124 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.67 | 0.67 | - |
| Only index persons | 0.85 | 0.85 | - |
| Median age at first event (years) | |||
| Whole population | - | 29.44 | - |
| Only index persons | - | 29.44 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3563 | 3563 | - |
| Unadjusted period prevalence (%) | 1.26 | 1.26 | - |
| Median age at first event (years) | 29.67 | 29.67 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 3700
- Matched controls
- 37000
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
8019.7
307.7
2407
7
A05AA02
ATC
ursodeoxycholic acid; oral
78.6
307.7
1027
180
63900
ICD-8 Finland
Other toxaemias of pregnancy and the puerperium, Pruritus
+∞
307.7
627
*
6467A
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Liver disorders in pregnancy[HEPATOSIS GRAVIDARUM]
+∞
307.7
733
*
63998
ICD-8 Finland
Other toxaemias of pregnancy and the puerperium, Alia definitae
30.2
116.7
77
26
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.3
115.7
1305
7116
O80.8
ICD-10 Finland
Other single spontaneous delivery
3.0
95.8
459
1642
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
2.4
90.9
745
3490
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2.3
82.7
746
3631
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.8
80.3
455
1776
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.9
76.1
1649
11006
W84
ICPC
Pregnancy high risk
3.0
72.9
353
1263
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
2.4
72.9
584
2687
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.3
68.4
580
2730
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
3.4
68.2
253
771
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
1.9
68.1
1143
6958
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
2.1
60.7
663
3447
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.0
55.6
674
3631
SPAT1380
SPAT
Postpartum check-up
2.0
53.1
724
4061
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
3.5
52.2
189
566
Z39.2
ICD-10 Finland
Routine postpartum follow-up
1.8
51.9
986
6150
SPAT1379
SPAT
Health check-up of pregnant person
1.9
51.9
824
4859
O30.0
ICD-10 Finland
Twin pregnancy
3.8
51.3
164
452
SPAT1197
SPAT
Extensive health check-up of expecting family
1.8
46.3
911
5712
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
2.2
44.2
435
2155
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.6
43.9
1650
12255
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
1.7
43.1
1007
6611
XMA22
NOMESCO Finland
General examination of pregnant woman
2.1
42.1
442
2242
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
1.8
41.6
727
4383
MAC96
NOMESCO Finland
Other induction or advancement of labour
2.8
41.1
215
798
W78
ICPC
Pregnancy
1.7
39.8
1033
6950
O60
ICD-10 Finland
Preterm labour and delivery
2.8
39.2
209
783
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
4.4
37.7
95
220
Z32.1
ICD-10 Finland
Pregnancy confirmed
1.8
37.5
700
4291
MAX99
NOMESCO Finland
Assistance to normal delivery
1.8
36.5
667
4058
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
2.4
35.4
251
1081
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
2.3
34.5
265
1182
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
2.7
30.0
166
634
WX307
NOMESCO Finland
Obstetric epidural analgesia
1.7
29.8
584
3607
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.7
29.5
602
3761
63901
ICD-8 Finland
Other toxaemias of pregnancy and the puerperium, Interus gravis
+∞
29.2
28
*
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
2.0
28.9
319
1641
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
1.8
28.8
448
2584
O99.80
ICD-10 Finland
The fear of childbirth
1.9
28.5
368
1998
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
1.6
26.5
694
4612
63909
ICD-8 Finland
Other toxaemias of pregnancy and the puerperium, Necrosis acuta et subacuta hepatis
+∞
26.1
25
*
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
1.6
25.2
671
4474
MAA00
NOMESCO Finland
Amniocentesis
2.5
24.8
165
690
O82.0
ICD-10 Finland
Delivery by elective caesarean section
1.9
24.2
306
1648
5742A
ICD-9 Finland
Cholelithiasis, Calculus of gallbladder without mention of cholecystitis[CHOLECYSTOLITHIASIS SINE CHOLECYSTITIDE,SINE OBSTR]
3.5
24.1
83
241
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
2.0
24.1
277
1444
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
2.5
24.1
156
644
W29
ICPC
Pregnancy symptom/complaint other
2.3
23.9
194
884
L29.9
ICD-10 Finland
Pruritus, unspecified
2.7
23.6
130
496
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
1.6
23.1
559
3633
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
3.0
21.5
96
327
SPAT1196
SPAT
Monitoring of normal pregnancy
1.7
21.4
438
2724
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
1.8
21.3
354
2077
8811
FHL
Cesarean section
1.9
19.7
279
1557
ZXE00
NOMESCO Finland
One hour or less
1.4
19.7
1386
11127
ZXD05
NOMESCO Finland
Urgent procedure
1.4
19.5
1096
8463
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
19.4
1452
11770
W90
ICPC
Uncompl labour/delivery livebirth
1.8
19.4
319
1865
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
2.7
18.8
102
387
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
1.7
18.7
359
2192
S02
ICPC
Pruritus
2.3
18.1
141
632
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
3.7
17.5
54
146
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
2.5
17.0
104
419
OAA12, ,
SPAT
1.9
16.8
226
1241
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
2.8
16.4
81
293
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
2.2
16.1
134
618
W92
ICPC
Compl labour/ delivery livebirth
2.1
15.6
144
692
6663
FHL
Cholecystectomy and cholangiography
3.6
15.3
49
136
W85
ICPC
Gestational diabetes
1.7
15.3
262
1548
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
2.3
15.1
115
511
OAA11, ,
SPAT
1.7
15.1
304
1878
K76.9
ICD-10 Finland
Liver disease, unspecified
3.1
14.8
61
199
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
2.8
14.6
74
271
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
1.9
14.5
175
928
6510B
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, SYNNYTYKSEN AIKANA]
3.7
14.3
45
124
V230A
ICD-9 Finland
Supervision of high-risk pregnancy, Pregnancy with history of infertility
3.0
14.1
61
205
A10BX01
ATC
guar gum; oral
2.7
14.1
74
277
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
2.3
13.9
103
454
O30.00
ICD-10 Finland
Twin pregnancy with separate amniotic and chorionic sacs
3.8
13.9
41
108
Z3232
NOMESCO Finland
Midwife
1.5
13.8
513
3642
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
2.3
13.7
107
481
O84.2
ICD-10 Finland
Multiple delivery, all by caesarean section
3.8
13.7
41
109
6467X
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Liver disorders in pregnancy[HEPATOPATHIA ALIA GRAVIDARUM]
+∞
13.5
13
*
O26.9
ICD-10 Finland
Pregnancy-related condition, unspecified
3.4
13.5
48
143
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
2.0
13.4
142
720
Z37.0
ICD-10 Finland
Single live birth
1.4
13.2
559
4066
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
1.7
13.2
249
1512
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
2.6
13.2
73
281
MA3AE
NOMESCO Finland
Combined first trimester screening
1.6
12.9
316
2049
K83.0
ICD-10 Finland
Cholangitis
3.7
12.7
40
110
O61.0
ICD-10 Finland
Failed medical induction of labour
2.6
12.7
74
292
O20.0
ICD-10 Finland
Threatened abortion
1.9
12.4
149
789
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
12.4
376
2559
A02BC01
ATC
omeprazole; systemic
1.4
12.3
815
6389
OAA10, ,
SPAT
1.8
12.2
198
1152
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
3.2
12.2
47
148
WX320
NOMESCO Finland
Spinalanesthesy
1.4
12.1
702
5385
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
2.5
12.0
72
288
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
2.9
12.0
54
186
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
1.6
12.0
318
2100
O98.4
ICD-10 Finland
Viral hepatitis complicating pregnancy, childbirth and the puerperium
10.1
12.0
23
23
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
11.8
634
4801
SPAT1357
SPAT
Monitoring of problem during pregnancy
1.8
11.7
161
891
SPAT1200
SPAT
Guidance for breast-feeding and breast care
1.8
11.6
159
879
Z39.1
ICD-10 Finland
Care and examination of lactating mother
1.9
11.6
136
715
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
11.6
1484
12709
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
2.1
11.3
107
522
O61.8
ICD-10 Finland
Other failed induction of labour
3.7
11.1
34
92
OAA41, ,
SPAT
2.0
11.0
117
595
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
2.2
11.0
93
434
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
1.8
10.9
164
933
Z36.8
ICD-10 Finland
Other antenatal screening
2.0
10.8
121
626
O47
ICD-10 Finland
False labour
2.6
10.8
60
232
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
2.0
10.7
112
567
SPAT1263
SPAT
Sampling
1.3
10.6
1404
12029
L29.8
ICD-10 Finland
Other pruritus
2.8
10.6
50
177
O26.0
ICD-10 Finland
Excessive weight gain in pregnancy
8.5
10.5
22
26
B18.2
ICD-10 Finland
Chronic viral hepatitis C
3.0
10.5
44
146
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
1.9
10.4
123
649
63902, ,
ICD-8 Finland
+∞
10.4
10
*
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.4
10.4
573
4352
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
1.9
10.3
137
753
MAC98
NOMESCO Finland
Other induction of labor
4.7
10.2
23
49
O21.0
ICD-10 Finland
Mild hyperemesis gravidarum
2.3
10.2
71
306
6480A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Diabetes mellitus
3.5
10.2
34
98
Z2221
NOMESCO Finland
Medical doctor
1.3
10.1
950
7788
P01AB01
ATC
metronidazole; oral, rectal
1.3
10.0
1526
13270
A10AC01
ATC
insulin (human); parenteral
1.7
10.0
194
1189
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.4
9.9
415
3008
6510A
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, RASKAUDEN AIKANA]
3.7
9.9
30
81
65007
ICD-8 Finland
Delivery without mention of complication, Multiple pregnancy, all presentations
4.9
9.8
21
43
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
4.9
9.8
21
43
Y6099
ICD-8 Finland
Prenatal care and observation
1.8
9.8
149
853
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
1.3
9.7
714
5656
K80.1
ICD-10 Finland
Calculus of gallbladder with other cholecystitis
2.3
9.7
71
312
57409
ICD-8 Finland
Cholelithiasis, Unspecified
3.4
9.7
34
101
SPAT1189
SPAT
Other ultrasound examination during pregnancy
1.7
9.7
182
1105
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
1.8
9.6
143
812
6488A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Abnormal glucose tolerance
2.3
9.6
69
302
SPAT1246
SPAT
Screening of depression or other psychiatric problem
1.6
9.4
213
1355
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
9.4
1156
9790
O84.8
ICD-10 Finland
Other multiple delivery
4.5
9.3
22
49
W27
ICPC
Fear of complications of pregnancy
2.3
9.1
64
277
B01AB04
ATC
dalteparin; parenteral
1.7
9.0
145
843
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
1.7
9.0
168
1020
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
2.1
8.7
81
393
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
1.7
8.7
149
882
W03
ICPC
Antepartum bleeding
2.5
8.7
51
203
WX234
NOMESCO Finland
Paracervical blockade
1.7
8.7
169
1037
G03DA04
ATC
progesterone; systemic, rectal, vaginal
1.7
8.6
159
961
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
8.4
1058
8956
K30
ICD-10 Finland
Functional dyspepsia
1.4
8.3
387
2854
O32.1
ICD-10 Finland
Maternal care for breech presentation
1.5
8.3
230
1536
O26.7
ICD-10 Finland
Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
2.2
8.2
65
296
OAA70, ,
SPAT
2.0
8.2
86
437
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
2.2
8.1
64
292
O72.0
ICD-10 Finland
Third-stage haemorrhage
1.7
7.9
127
740
J01DB01
ATC
cefalexin; oral
1.3
7.9
2942
27858
G03DB01
ATC
dydrogesterone; oral
1.3
7.8
640
5134
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
1.5
7.8
228
1539
O36.9
ICD-10 Finland
Maternal care for fetal problem, unspecified
2.3
7.7
58
259
6440B
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS]
2.2
7.7
64
299
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
1.8
7.6
110
621
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.2
7.6
1663
14874
WX306
NOMESCO Finland
Lumbar epidural anesthesy
1.4
7.6
336
2456
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
1.9
7.6
93
499
W94
ICPC
Puerperal mastitis
2.5
7.6
45
181
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
3.1
7.4
30
98
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
1.7
7.4
120
702
6500B
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
1.3
7.3
731
6011
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.5
7.3
259
1819
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
2.7
7.3
36
132
Z71.8
ICD-10 Finland
Other specified counselling
1.2
7.2
1118
9653
R51.80
ICD-10 Finland
Headache
1.3
7.2
599
4814
SPAT1373
SPAT
Combined screening in early pregnancy
1.8
7.2
94
516
O02.1
ICD-10 Finland
Missed abortion
1.4
7.2
287
2062
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.2
7.2
1041
8926
1413
FHL
Laparoscopy and other therapeutic procedure
1.9
7.1
91
496
SPAT1391
SPAT
Counselling and guidance related to family situation
2.1
7.1
64
309
K50.9
ICD-10 Finland
Crohn disease, unspecified
2.3
7.1
52
231
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
2.9
7.0
32
112
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.0
7.0
74
378
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
4.0
6.9
19
48
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
1.6
6.9
148
934
O91.2
ICD-10 Finland
Nonpurulent mastitis associated with childbirth
2.0
6.8
65
320
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
1.8
6.8
101
576
L04AX01
ATC
azathioprine; systemic
1.7
6.8
128
780
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.4
6.8
273
1962
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
2.9
6.8
31
109
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
1.8
6.7
92
512
Z37.2
ICD-10 Finland
Twins, both liveborn
3.4
6.7
23
68
6440A
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS IMMINENS]
1.9
6.7
79
420
O98.8
ICD-10 Finland
Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium
7.8
6.6
14
18
SPAT1307
SPAT
Psychosocial counselling and guidance
1.4
6.6
259
1855
SPAT1190
SPAT
Insertion or removal of intrauterine contraceptive device
1.4
6.5
317
2354
TQW30
NOMESCO Finland
Acupuncture
2.6
6.5
36
140
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.2
6.5
1072
9296
G03GB02
ATC
clomifene; oral
1.7
6.5
106
623
Z34
ICD-10 Finland
Supervision of normal pregnancy
1.4
6.5
242
1718
SPAT1375
SPAT
Structural ultrasound screening, weeks 18+0-21+6
2.0
6.4
62
307
O40
ICD-10 Finland
Polyhydramnios
2.0
6.4
62
307
6662
FHL
Cholecystectomy
2.6
6.4
34
130
SFA20
NOMESCO Finland
Two-surface restoration
1.2
6.4
2158
19968
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
1.3
6.3
699
5808
O86.1
ICD-10 Finland
Other infection of genital tract following delivery
2.3
6.3
46
204
Z22.5
ICD-10 Finland
Carrier of viral hepatitis
11.0
6.3
11
10
W99
ICPC
Disorder of pregn/delivery other
2.9
6.3
27
92
O83.8
ICD-10 Finland
Other specified assisted single delivery
3.8
6.3
18
47
O86.0
ICD-10 Finland
Infection of obstetric surgical wound
2.2
6.2
47
212
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.4
6.2
233
1658
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
1.7
6.1
103
610
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
1.7
6.1
101
596
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
2.1
6.1
55
266
O26.5
ICD-10 Finland
Maternal hypotension syndrome
10.0
6.0
11
11
G03AC03
ATC
levonorgestrel; oral, implant
1.3
6.0
491
3933
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
866
816
13.55
307.65
6.1
1.5
10.13
4.41
umol/l
14.15
767
568
308
599
5.52
151.58
1.3
1.3
107.44
111.08
u/ml
0.31
58
133
319
650
5.28
148.98
1.2
1.3
14.08
20.97
u/ml
—
5
15
310
666
4.99
135.93
1.2
1.2
199.72
268.79
u/ml
5.63
248
433
321
712
4.84
135.49
1.2
1.2
—
—
—
0
0
120
185
6.67
74.47
1.1
1.2
—
—
—
0
0
706
4358
1.77
36.82
1.6
1.5
—
—
—
0
0
1813
14307
1.52
33.69
5.2
5.4
9.61
9.61
umol/l
0.01
1711
13495
547
3217
1.82
33.30
2.4
2.4
5.98
5.94
umol/l
0.02
481
2704
198
851
2.40
27.97
1.4
1.2
72.00
192.43
titre
0.92
15
74
1351
10426
1.47
25.72
3.4
3.0
33.72
29.08
u/l
2.86
1292
9973
368
2082
1.85
25.04
1.7
1.5
—
—
—
0
0
474
2906
1.72
24.54
1.5
1.4
—
—
—
0
0
3531
33442
2.22
23.36
11.2
8.8
31.29
23.78
u/l
37.65
3460
32478
2531
22245
1.44
22.06
7.5
6.8
79.03
72.74
u/l
12.03
2396
21050
329
1868
1.84
22.06
1.9
1.7
—
—
—
0
0
305
1782
1.78
18.54
1.8
1.9
1.47
1.36
g/l
0.30
279
1651
371
2304
1.68
18.09
2.5
2.7
10.39
10.37
g/l
0.04
338
2133
373
2350
1.65
17.19
1.5
1.4
—
—
—
0
0
372
2344
1.65
17.13
1.5
1.4
—
—
—
0
0
1112
8765
1.38
17.06
2.4
2.4
59.03
57.41
u/l
0.19
1042
8110
373
2359
1.65
16.92
1.5
1.4
—
—
—
0
0
372
2357
1.64
16.75
1.5
1.4
—
—
—
0
0
393
2527
1.62
16.68
1.6
1.5
—
—
—
0
0
271
1579
1.77
16.61
1.5
1.5
—
—
—
0
0
2370
21104
1.34
15.69
4.5
3.9
612.72
1705.94
e6/l
0.99
25
233
1613
13757
1.31
13.71
8.4
8.0
0.00
0.00
e9/l
0.49
1335
11283
1209
10024
1.31
12.30
6.5
7.9
1.06
1.08
inr
1.07
425
3245
341
2276
1.55
12.26
3.1
4.3
243.22
232.29
u/l
0.19
324
2149
328
2202
1.54
11.48
2.3
2.2
0.22
0.22
g/l
0.23
303
2088
2852
26533
1.33
11.38
4.0
3.7
—
—
—
0
0
910
7379
1.31
10.61
1.5
1.4
2.08
2.13
g/l
0.51
569
4686
1947
17344
1.26
10.55
3.2
2.9
64.06
70.71
ug/l
2.45
1852
16433
2453
22511
1.27
10.04
3.2
2.8
39.68
34.23
u/l
3.50
2320
21452
114
598
1.94
9.85
1.6
1.5
—
—
—
0
0
1294
11054
1.26
9.84
4.5
4.2
36.39
36.69
g/l
1.27
1207
10343
951
7837
1.29
9.67
3.0
2.8
33.69
81.49
e6/l
1.55
697
5839
1652
14593
1.24
9.11
6.6
6.0
8.01
7.92
%
0.60
1580
13736
3015
28511
1.31
9.05
13.8
12.6
15.70
14.40
%
0.48
2981
28044
1643
14518
1.24
9.00
6.4
5.7
2.84
2.77
%
0.83
1569
13625
1713
15213
1.23
8.92
2.6
2.4
—
—
—
0
0
56
231
2.45
8.87
1.1
1.0
315.49
298.07
mg/l
0.54
45
207
853
7003
1.28
8.82
3.9
3.2
99.56
98.94
%
0.35
825
6777
1772
15826
1.23
8.64
4.2
3.9
6.19
6.29
mmol/l
1.42
1596
14332
1583
13974
1.23
8.62
6.5
5.8
0.72
0.69
%
2.00
1510
13036
2499
23192
1.24
8.24
4.4
3.8
10.21
10.13
mm/h
0.12
2363
21813
74
356
2.10
8.19
1.1
1.1
1.41
1.48
g/l
0.61
63
318
1700
15195
1.22
7.98
6.3
5.7
29.87
29.80
%
0.12
1625
14354
861
7170
1.26
7.79
3.0
2.7
0.20
0.29
e6/l
1.34
634
5285
1674
15006
1.21
7.44
6.2
5.6
56.07
56.28
%
0.35
1607
14154
133
799
1.69
7.44
2.1
1.9
1.18
1.44
g/l
2.79
115
689
49
207
2.39
7.43
1.3
1.2
272.86
199.36
titre
0.25
14
47
1031
8807
1.24
7.38
1.3
1.3
1.04
1.59
u/ml
2.08
298
2562
3200
30708
1.31
7.20
5.3
5.1
1.69
2.01
mu/l
2.03
3031
29119
48
206
2.35
7.04
1.1
1.1
—
—
—
0
0
780
6497
1.25
6.95
1.3
1.3
10.21
9.27
u/ml
0.18
296
2768
107
626
1.73
6.63
1.9
1.5
9.03
10.87
iu/ml
—
6
12
163
1062
1.56
6.61
1.2
1.2
—
—
—
0
0
1745
15815
1.20
6.60
3.6
3.3
0.00
0.00
estimate
1.34
431
3167
111
658
1.71
6.56
1.8
1.6
7.59
7.64
mmol/l
0.09
103
630
410
3177
1.33
6.41
2.7
2.2
6781.95
5943.48
u/l
0.21
183
1307
1747
15872
1.19
6.33
5.0
4.5
0.00
0.00
estimate
0.80
422
3078
1773
16131
1.19
6.31
6.4
5.9
0.18
0.18
e9/l
0.25
1613
14487
1759
15997
1.19
6.28
3.6
3.3
0.00
0.01
estimate
1.80
427
3043
1767
16084
1.19
6.22
6.3
5.7
1.93
1.97
e9/l
0.90
1619
14571
510
4092
1.29
6.16
2.1
2.2
14.40
14.21
umol/l
0.24
474
3822
799
6785
1.23
5.86
1.3
1.3
25.88
27.82
iu/ml
0.17
253
2230
846
7231
1.22
5.82
2.3
2.1
2.56
2.74
mg/l
1.87
747
6211
657
5472
1.24
5.77
2.5
2.3
9.12
8.63
e6/l
0.13
579
4857
35
143
2.46
5.77
2.9
2.9
8.55
7.33
mg/l
0.46
28
108
1060
9269
1.20
5.74
1.7
1.7
—
—
—
0
0
352
2713
1.33
5.72
2.4
2.2
35.18
36.24
u/l
0.12
317
2308
795
6773
1.22
5.63
2.2
2.1
604.49
2729.09
umol/l
5.41
710
6098
2863
27307
1.21
5.62
4.7
4.4
14.38
14.37
pmol/l
0.11
2674
25679
482
3889
1.28
5.55
2.6
2.5
4.84
4.57
e6/l
0.12
245
1942
111
691
1.63
5.51
4.3
3.3
788.06
349.30
u/ml
0.35
96
591
76
431
1.78
5.32
1.3
1.2
—
—
—
0
0
841
7253
1.21
5.21
2.0
1.9
—
—
—
0
0
415
3320
1.28
5.12
2.2
2.3
23.36
23.56
%
0.11
358
2852
3291
31932
1.28
5.10
11.8
10.6
17.05
18.66
mg/l
2.46
2573
24599
183
1292
1.44
5.10
1.4
1.3
—
—
—
0
0
136
906
1.52
5.07
2.5
2.5
3.92
3.58
g/l
1.76
124
847
452
3666
1.27
4.99
2.2
2.2
2.48
2.47
g/l
0.24
415
3396
49
248
1.99
4.88
1.0
1.1
—
—
—
0
0
1484
13519
1.16
4.72
2.4
2.3
76.65
75.54
nmol/l
0.87
1378
12608
832
7248
1.19
4.56
1.9
1.7
1.03
0.86
mg/l
1.01
614
5394
3037
29297
1.20
4.46
9.9
9.1
90.71
90.38
ml/min/173m2
0.41
2548
23985
580
4895
1.22
4.44
3.0
2.3
105.43
98.05
ug/g
0.25
463
3859
1913
17809
1.15
4.43
8.3
8.6
3.84
3.91
e9/l
0.83
1699
15738
32
145
2.22
4.27
1.2
1.2
—
—
—
0
0
1382
12594
1.16
4.25
5.4
5.5
1.22
1.22
mmol/l
1.25
1184
10710
119
815
1.48
3.96
2.4
1.7
531.43
448.24
titre
—
7
34
3185
30943
1.21
3.91
10.8
10.3
139.66
139.64
mmol/l
0.27
3111
30112
413
3411
1.24
3.90
2.4
2.0
29.01
29.15
s
0.20
395
3300
3195
31052
1.21
3.89
10.9
10.4
3.89
3.90
mmol/l
2.27
3119
30134
31
145
2.15
3.86
1.2
1.2
—
—
—
0
0
498
4216
1.21
3.69
2.5
2.3
2.22
1.08
e6/l
0.58
260
2257
3627
35873
1.56
3.54
17.8
15.9
266.11
269.11
e9/l
2.30
3570
35192
237
3001
0.78
3.54
5.1
5.0
—
—
—
0
0
1144
10394
1.15
3.53
1.8
1.8
102.32
99.75
pmol/l
0.97
584
5438
818
7276
1.16
3.38
1.9
2.0
133.19
136.21
u/l
0.07
782
6893
3621
35816
1.52
3.35
17.8
15.8
39.52
39.87
%
1.55
3486
34244
1228
11247
1.14
3.32
5.0
4.9
1.22
1.22
mmol/l
1.17
1155
10334
49
285
1.73
3.28
1.1
1.2
—
—
—
0
0
3627
35894
1.53
3.27
17.8
15.9
6.63
6.64
e9/l
0.05
3566
35139
927
8344
1.15
3.24
3.6
3.6
0.01
0.00
estimate
0.39
424
3057
3627
35899
1.52
3.21
17.7
15.9
4.44
4.45
e12/l
1.13
3566
35173
97
669
1.46
3.19
1.7
1.4
6.44
6.87
mmol/l
1.11
83
605
32
165
1.95
3.13
1.9
1.5
2.29
5.84
u/l
2.64
24
141
153
1150
1.34
3.07
1.4
1.4
—
—
—
0
0
3627
35912
1.51
3.04
17.9
16.0
132.08
133.06
g/l
6.69
3603
35570
319
2637
1.23
3.03
1.3
1.3
193.85
158.78
u/ml
0.20
300
2451
204
1602
1.29
3.00
1.2
1.3
0.29
1.09
u/ml
2.04
16
141
46
272
1.70
2.94
1.0
1.1
8.09
9.07
iu/ml
0.10
12
77
331
2772
1.21
2.78
2.8
3.4
4.56
4.52
pmol/l
0.32
304
2494
1329
12337
1.12
2.78
3.6
3.3
—
—
—
0
0
142
1074
1.34
2.76
1.8
2.1
3.19
4.32
iu/l
1.68
50
434
38
220
1.73
2.64
1.4
1.4
—
—
—
0
0
162
1270
1.29
2.47
1.9
2.1
40.13
39.05
u/l
0.30
149
1169
622
5546
1.15
2.46
1.4
1.4
21.84
21.42
nmol/l
0.29
538
4892
300
2526
1.20
2.41
2.3
2.4
17.23
22.44
au/ml
0.60
15
250
9
224
0.40
2.41
7.4
12.3
854.78
864.22
nmol/l
—
9
214
48
305
1.58
2.38
1.2
1.1
—
58.03
—
0
6
289
2431
1.20
2.35
2.4
2.6
—
—
—
0
0
91
665
1.38
2.27
1.2
1.2
—
—
—
0
0
3024
29525
1.13
2.26
3.7
3.6
5.58
5.62
mmol/l
1.03
2827
27657
88
641
1.38
2.24
3.6
3.6
57.15
57.09
%
0.02
88
641
119
911
1.32
2.20
1.3
1.3
72.23
38.00
u/ml
—
9
91
276
2334
1.20
2.15
1.3
1.3
23.13
39.60
au/ml
—
6
120
432
3795
1.16
2.12
3.1
3.2
0.83
0.82
mmol/l
0.90
408
3579
358
3100
1.17
2.12
1.9
2.1
379.07
374.24
nmol/l
0.18
336
2850
49
323
1.52
2.11
1.9
1.6
—
—
—
0
0
14
292
0.48
2.11
1.4
1.4
—
—
—
0
0
14
292
0.48
2.11
1.4
1.4
—
—
—
0
0
61
423
1.45
2.06
2.0
1.7
36.00
27.05
iu/ml
—
5
22
150
1198
1.26
2.03
1.9
2.0
—
—
—
0
0
45
294
1.54
2.03
1.2
1.1
—
—
—
0
0
168
1363
1.24
1.99
1.7
1.7
—
—
—
0
0
58
402
1.45
1.98
1.1
1.2
—
—
—
0
0
129
1016
1.28
1.96
1.3
1.3
6.34
9.07
u/ml
0.33
16
172
10
229
0.44
1.95
12.7
18.0
1407.10
5704.20
nmol/l
—
10
220
936
8674
1.11
1.92
2.6
2.7
25.63
29.77
ng/l
0.21
392
3964
21
113
1.86
1.91
1.0
1.1
—
—
—
0
0
88
663
1.34
1.86
1.2
1.1
12.11
11.79
au/ml
0.02
12
41
11
46
2.40
1.85
1.3
1.2
—
—
—
0
0
5
12
4.17
1.82
1.0
1.0
—
—
—
0
0
812
7490
1.11
1.82
1.6
1.6
1.25
1.34
mmol/l
2.12
711
6481
126
1003
1.27
1.79
1.3
1.3
6.51
5.74
u/ml
0.07
11
106
2744
26752
1.10
1.78
4.5
4.4
37.41
37.68
mmol/mol
1.05
2590
25249
70
513
1.37
1.78
3.4
5.0
123.71
501.93
iu/ml
—
7
59
685
6271
1.11
1.77
4.2
3.7
10.19
9.49
mg/mmol
0.17
421
3791
138
1113
1.25
1.76
1.4
1.5
—
—
—
0
0
11
48
2.30
1.70
1.2
1.2
—
—
—
0
0
523
4730
1.12
1.68
2.5
2.6
663.88
599.75
ng/l
0.14
423
3856
158
1303
1.22
1.65
2.3
2.6
71.74
104.03
ng/l
2.27
138
1156
71
529
1.35
1.65
1.8
1.7
16640.50
8248.71
e6/l
0.63
52
390
396
3527
1.14
1.64
1.3
1.2
179.61
156.92
iu/ml
0.46
157
1411
46
319
1.45
1.62
2.8
2.4
63.74
62.12
%
0.19
46
319
44
304
1.45
1.58
1.3
1.2
—
—
—
0
0
187
1577
1.20
1.57
2.2
2.6
66.88
67.38
g/l
0.45
173
1460
246
2125
1.17
1.56
2.0
2.6
1.63
1.74
%
1.14
214
1884
44
305
1.45
1.56
1.3
1.2
—
—
—
0
0
466
4208
1.12
1.55
3.0
2.8
282.71
318.78
ng/l
0.12
257
2299
131
1068
1.23
1.55
1.2
1.2
—
—
—
0
0
22
130
1.70
1.52
1.1
1.1
—
—
—
0
0
44
307
1.44
1.51
1.3
1.1
—
—
—
0
0
44
307
1.44
1.51
1.3
1.1
—
—
—
0
0
76
581
1.31
1.51
1.5
1.4
—
—
—
0
0
24
146
1.65
1.50
1.2
1.2
—
—
—
0
0
44
308
1.43
1.49
1.3
1.2
—
—
—
0
0
10
204
0.49
1.48
1.9
2.4
—
—
—
0
0
353
3143
1.14
1.48
3.6
3.6
33.40
32.81
%
0.49
263
2329
653
6022
1.10
1.48
3.6
3.2
373.46
465.19
mg/l
0.20
406
3599
9
37
2.44
1.47
1.0
1.3
—
—
—
0
0
185
1572
1.19
1.45
7.5
7.4
7.75
7.49
mmol/l
0.23
176
1515
137
1132
1.22
1.44
1.3
1.3
85.86
39.48
u/ml
—
5
82
26
164
1.59
1.43
1.2
1.1
96.27
93.85
%
0.22
11
67
36
245
1.47
1.42
2.0
1.3
—
—
—
0
0
142
1184
1.21
1.38
2.5
2.5
0.30
0.26
e6/l
0.16
135
1123
13
67
1.94
1.38
1.1
1.1
—
—
—
0
0
58
435
1.34
1.34
2.0
1.3
—
106.67
—
0
6
1084
10268
1.08
1.32
1.5
1.5
—
—
—
0
0
768
7178
1.09
1.30
3.7
3.1
7.29
7.25
mmol/l
0.08
676
6272
793
7433
1.09
1.26
2.1
2.1
—
—
—
0
0
18
107
1.69
1.25
31.3
25.1
111.50
100.45
ug/l
0.29
18
89
6
25
2.40
1.24
1.0
1.2
—
—
—
0
0
604
5600
1.09
1.24
1.6
1.6
14953704.90
38961738.89
pmol/l
0.79
535
4833
22
139
1.59
1.23
1.3
1.7
—
—
—
0
0
41
560
0.73
1.22
1.5
1.5
—
—
—
0
0
11
56
1.97
1.22
5.1
4.9
—
—
—
0
0
29
419
0.69
1.20
1.5
1.5
—
—
—
0
0
29
419
0.69
1.20
1.5
1.5
—
—
—
0
0
234
2063
1.14
1.19
3.2
3.2
1.23
1.23
mmol/l
1.05
214
1779
79
633
1.25
1.15
2.9
2.2
0.40
0.55
g/l
0.27
74
571
15
87
1.73
1.15
1.4
6.9
11863.60
62.45
mg/l
—
10
58
24
158
1.52
1.14
1.2
1.1
101.36
96.75
%
0.37
11
65
30
426
0.70
1.14
1.6
1.4
—
—
—
0
0
707
6629
1.08
1.12
2.0
2.0
—
—
—
0
0
198
1735
1.15
1.11
1.5
1.6
—
—
—
0
0
36
259
1.39
1.11
1.2
1.2
—
—
—
0
0
122
1029
1.19
1.10
2.2
2.0
—
—
—
0
0
208
2355
0.88
1.09
1.4
1.5
—
—
—
0
0
977
9285
1.07
1.08
2.9
3.1
2.35
2.35
mmol/l
0.09
865
8436
247
2204
1.13
1.07
1.9
1.8
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
30
211
1.43
1.06
1.9
1.8
125.97
120.34
%
0.18
30
203
36
262
1.38
1.05
1.2
1.2
—
—
—
0
0
389
3564
1.10
1.05
1.7
1.7
—
—
—
0
0
126
1072
1.18
1.04
1.5
1.6
—
—
—
0
0
88
724
1.22
1.04
2.2
2.2
—
—
—
0
0
60
473
1.27
1.03
1.2
1.2
—
—
—
0
0
60
473
1.27
1.03
1.2
1.2
—
—
—
0
0
21
138
1.52
1.02
1.3
1.4
144.42
139.76
mmol/24h
0.12
21
138
131
1123
1.17
1.00
2.3
1.9
0.23
0.23
g/l
0.16
126
1053
110
931
1.19
0.98
2.1
1.8
—
—
—
0
0
126
1079
1.17
0.98
1.5
1.6
0.05
0.37
iu/ml
1.13
21
202
5
23
2.18
0.98
1.2
1.0
8.16
8.07
mmol/l
—
5
23
134
1154
1.17
0.97
1.1
1.1
7.40
5.52
u/ml
0.11
20
178
22
149
1.48
0.95
1.1
1.3
—
—
u/ml
—
0
0
73
596
1.23
0.95
1.4
1.2
2.29
4.74
u/ml
2.74
28
234
26
363
0.71
0.93
5.4
5.6
376.42
377.30
umol/l
0.01
19
311
95
1124
0.84
0.92
5.7
7.1
24.76
24.39
mmol/l
0.49
87
1065
19
126
1.51
0.91
1.3
1.2
—
—
—
0
0
427
3965
1.09
0.89
1.7
1.6
1124.29
1189.84
nmol/l
0.88
343
3074
108
1259
0.85
0.88
1.3
1.2
11.85
11.95
u/l
0.03
90
1047
371
3425
1.09
0.88
1.3
1.3
27.95
27.29
iu/l
0.14
331
2978
38
290
1.31
0.86
1.3
1.4
—
—
—
0
0
206
2289
0.89
0.84
1.5
1.4
—
—
—
0
0
25
179
1.40
0.84
3.4
2.7
40704.80
39321.69
ug/l
0.19
25
179
44
557
0.79
0.83
1.5
1.5
—
—
—
0
0
22
154
1.43
0.83
1.3
1.6
0.77
2.93
u/field
1.75
13
107
95
809
1.18
0.83
2.0
2.1
10.21
10.66
mg/l
0.22
89
759
6
32
1.88
0.81
1.2
1.1
—
—
—
0
0
306
2813
1.10
0.81
5.1
5.0
1.05
1.04
mmol/l
0.33
286
2629
54
436
1.24
0.80
2.3
2.6
14.83
91.12
ug/min
3.74
37
276
29
215
1.35
0.80
1.2
1.2
—
—
—
0
0
37
285
1.30
0.80
1.7
1.7
53.33
51.51
%
0.09
24
166
74
620
1.20
0.78
1.3
1.2
1.28
3.13
u/ml
2.56
25
199
5
99
0.50
0.77
4.4
2.7
—
—
—
0
0
89
760
1.18
0.76
1.4
1.4
320.89
313.58
ug/g
0.12
44
390
157
1399
1.13
0.75
1.6
1.5
—
—
—
0
0
14
91
1.54
0.75
1.1
1.1
—
—
—
0
0
164
1467
1.12
0.74
2.1
2.5
65.11
72.55
e9/l
2.44
116
1072
200
2206
0.90
0.74
2.3
2.3
73.08
75.44
ml/min/173m2
0.42
73
836
72
606
1.19
0.74
1.2
1.1
—
—
—
0
0
40
502
0.79
0.73
1.1
1.1
2.13
19850.12
iu/ml
—
8
135
5
25
2.00
0.72
1.2
1.1
—
—
—
0
0
31
237
1.31
0.72
1.1
1.2
1.56
1.61
g/l
0.59
31
237
6
109
0.55
0.72
3.8
2.3
125.17
164.02
nmol/l
—
6
93
9
57
1.58
0.71
1.0
1.3
—
—
—
0
0
435
4086
1.07
0.71
1.6
1.6
1.33
1.32
%
0.10
382
3689
130
1465
0.88
0.70
2.1
2.1
—
—
—
0
0
3099
30676
1.06
0.70
3.8
3.7
4.80
4.88
mmol/l
5.73
2963
29231
49
399
1.23
0.70
1.2
1.4
—
3728.00
—
0
5
211
1927
1.10
0.67
1.4
1.3
229.22
242.24
miu/ml
0.21
106
997
26
196
1.33
0.67
1.3
1.5
71.19
67.92
umol/l
0.44
26
196
103
1173
0.87
0.67
14.8
8.0
94.22
94.24
%
0.01
103
1168
5
28
1.79
0.66
1.2
2.0
0.60
0.93
u/field
—
5
28
241
2218
1.09
0.66
1.5
1.5
—
—
—
0
0
28
359
0.78
0.63
1.6
1.5
—
—
—
0
0
78
673
1.16
0.63
1.1
1.1
—
—
—
0
0
21
280
0.75
0.62
1.4
1.5
—
—
—
0
0
25
190
1.32
0.62
1.6
1.9
0.70
2.15
u/field
—
10
98
103
1166
0.88
0.62
1.3
1.3
3.02
3.77
ug/l
0.98
95
1076
41
333
1.23
0.62
1.0
1.1
189.59
213.53
mg/l
0.97
35
294
23
302
0.76
0.62
1.6
1.4
—
—
—
0
0
30
380
0.79
0.62
1.6
1.6
—
—
—
0
0
243
2246
1.09
0.61
1.1
1.0
—
—
—
0
0
112
994
1.13
0.61
1.2
1.1
2.23
2.39
u/ml
0.06
58
470
0
20
0.00
0.60
0.0
1.0
—
0.18
—
0
7
43
353
1.22
0.60
1.3
1.4
—
—
—
0
0
42
345
1.22
0.58
1.3
1.4
—
—
—
0
0
42
345
1.22
0.58
1.3
1.4
—
—
—
0
0
65
557
1.17
0.58
1.1
1.2
—
—
—
0
0
31
387
0.80
0.57
1.1
1.1
—
—
—
0
0
234
2168
1.08
0.57
1.7
1.6
397.41
305.78
mu/l
0.31
205
1916
104
1168
0.89
0.57
14.7
8.0
0.70
0.69
%
0.06
104
1162
21
275
0.76
0.56
1.1
1.1
—
—
—
0
0
30
375
0.80
0.56
1.2
1.5
—
—
—
0
0
36
292
1.24
0.56
1.9
1.9
19.31
26.41
mg/l
—
9
74
72
828
0.87
0.56
1.2
1.2
—
—
—
0
0
19
252
0.75
0.56
1.4
2.1
—
—
—
0
0
42
347
1.21
0.56
1.3
1.4
—
—
—
0
0
19
251
0.76
0.55
1.5
1.6
—
—
—
0
0
48
404
1.19
0.54
2.3
2.2
—
—
—
0
0
186
1714
1.09
0.53
1.8
1.7
3.04
4.03
mg/l
1.32
144
1236
82
722
1.14
0.53
3.3
5.2
1.75
1.68
%
0.13
75
675
10
66
1.52
0.52
1.3
1.2
8.00
12.66
u/l
—
10
59
124
1122
1.11
0.51
3.4
2.9
1.81
1.63
mmol/l
0.23
80
834
14
100
1.40
0.51
1.1
1.2
99.57
108.54
%
0.57
14
95
6
40
1.50
0.51
1.2
1.2
—
—
—
0
0
6
40
1.50
0.51
1.2
1.2
—
—
—
0
0
43
360
1.20
0.51
1.8
1.6
—
—
—
0
0
43
360
1.20
0.51
1.3
1.4
—
—
—
0
0
105
1168
0.90
0.51
14.6
7.9
1.14
1.33
%
1.83
105
1160
41
343
1.20
0.50
1.1
1.1
41.87
33.54
mg/l
0.31
31
289
38
316
1.20
0.49
1.1
1.1
—
—
—
0
0
42
353
1.19
0.49
1.3
1.4
—
—
—
0
0
159
1727
0.92
0.49
11.0
7.6
119.01
120.97
g/l
0.68
152
1682
94
841
1.12
0.48
1.1
1.1
0.89
1.56
u/ml
0.65
44
395
66
577
1.15
0.48
1.2
1.3
—
—
—
0
0
3121
30976
1.05
0.48
4.0
3.9
2.87
2.92
mmol/l
2.95
2962
29353
57
493
1.16
0.48
1.7
2.3
130.98
130.18
g/l
0.12
45
370
13
93
1.40
0.48
1.7
1.3
519.84
353.59
u/l
0.39
13
88
78
692
1.13
0.47
1.8
1.9
—
—
—
0
0
413
3938
1.05
0.46
1.6
1.6
—
—
—
0
0
27
218
1.24
0.46
1.9
1.5
48.22
41.34
%
0.38
19
121
77
684
1.13
0.45
1.4
1.6
—
—
—
0
0
2959
29346
1.04
0.45
3.4
3.3
1.12
1.20
mmol/l
13.56
2819
27758
77
685
1.13
0.45
1.1
1.1
0.98
3.71
u/ml
5.22
32
256
23
285
0.81
0.43
1.4
1.5
—
—
—
0
0
14
185
0.76
0.43
1.3
1.6
—
—
—
0
0
48
415
1.16
0.42
1.1
1.1
95.81
95.36
%
0.04
48
385
6
92
0.65
0.42
1.3
2.3
18.08
16.00
umol/l
—
6
92
5
32
1.56
0.42
1.4
1.1
—
—
—
0
0
8
58
1.38
0.41
1.1
1.6
—
—
—
0
0
5
33
1.52
0.41
1.0
1.1
—
—
—
0
0
3075
30537
1.04
0.41
3.7
3.6
1.57
1.57
mmol/l
0.06
2933
29020
194
1816
1.07
0.41
3.4
3.3
72.75
73.94
ng/l
0.08
172
1607
113
1034
1.10
0.41
1.4
1.4
27.05
25.06
u/l
0.25
90
864
11
79
1.39
0.40
2.2
3.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
0.29
—
0
6
235
2218
1.06
0.39
4.3
3.7
59.63
33.48
ug/l
0.26
179
1631
5
35
1.43
0.39
1.0
1.1
—
—
—
0
0
15
193
0.78
0.39
1.2
1.3
—
—
—
0
0
18
225
0.80
0.38
1.5
1.5
—
—
—
0
0
12
89
1.35
0.37
1.2
1.2
—
—
—
0
0
12
89
1.35
0.37
1.2
1.2
—
—
—
0
0
30
354
0.85
0.36
1.6
1.4
—
—
—
0
0
57
507
1.13
0.36
2.5
2.6
—
—
—
0
0
198
2097
0.94
0.35
9.7
6.8
0.68
0.90
mmol/l
0.34
158
1641
9
126
0.71
0.35
3.3
2.2
1.92
1.02
ug/l
—
9
118
70
635
1.10
0.32
2.8
2.1
153.65
329.62
ug/l
0.70
59
558
44
497
0.88
0.32
1.4
1.4
33.85
31.85
nmol/l
0.16
37
444
12
92
1.31
0.31
2.4
2.1
—
—
—
0
0
11
84
1.31
0.30
1.0
1.1
—
—
—
0
0
12
93
1.29
0.30
1.0
1.3
—
—
—
0
0
42
372
1.13
0.30
1.2
1.1
—
—
—
0
0
8
108
0.74
0.29
1.0
1.0
—
—
—
0
0
8
108
0.74
0.29
2.0
1.4
—
—
—
0
0
80
737
1.09
0.28
1.1
1.2
3.60
3.59
mmol/l
0.06
74
693
126
1183
1.07
0.28
3.7
3.0
5.12
5.14
kpa
0.12
117
1140
17
205
0.83
0.28
1.5
1.5
—
—
—
0
0
17
205
0.83
0.28
1.5
1.5
—
—
—
0
0
17
205
0.83
0.28
1.5
1.5
—
—
—
0
0
8
63
1.27
0.27
1.8
1.7
13.59
68.68
u/l
—
8
56
689
6733
1.03
0.27
3.7
3.6
1.02
1.02
kg/l
0.24
120
1011
95
885
1.08
0.27
1.1
1.1
3.00
5.57
u/ml
1.34
44
451
12
95
1.26
0.26
1.1
1.1
95.00
98.02
%
0.15
12
95
17
141
1.21
0.26
1.2
1.4
12.44
14.04
pmol/l
0.97
17
116
32
282
1.14
0.25
1.1
1.1
1.08
1.04
ratio
0.47
14
107
9
75
1.20
0.25
1.1
1.3
—
—
—
0
0
34
302
1.13
0.24
1.1
1.2
0.60
1.19
u/ml
0.64
15
136
143
1359
1.05
0.23
3.0
2.8
4.76
4.63
kpa
0.26
137
1309
15
179
0.84
0.23
1.9
2.8
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
15
178
0.84
0.22
1.3
1.1
—
—
—
0
0
89
836
1.07
0.21
1.1
1.3
439.79
450.65
mg/l
0.09
82
800
30
267
1.12
0.21
1.2
1.6
—
—
—
0
0
67
623
1.08
0.21
1.2
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
28.58
—
0
12
8
105
0.76
0.21
2.0
1.4
—
—
—
0
0
89
838
1.06
0.20
1.1
1.1
0.79
1.03
u/ml
0.22
33
336
54
499
1.08
0.20
1.4
1.3
1.11
1.40
nmol/l
1.05
42
425
202
2096
0.96
0.20
9.5
6.8
5.04
5.05
kpa
0.03
193
2009
202
2096
0.96
0.20
9.5
6.8
13.49
13.55
kpa
0.04
193
2006
13
108
1.20
0.20
1.2
1.2
—
—
—
0
0
13
108
1.20
0.20
1.0
4.9
—
379.36
—
0
14
79
742
1.07
0.20
1.1
1.1
1.23
4.46
u/ml
2.15
36
326
6
50
1.20
0.19
1.0
1.0
—
—
—
0
0
15
127
1.18
0.19
1.6
1.6
—
—
—
0
0
15
127
1.18
0.19
1.6
1.6
—
—
—
0
0
114
1086
1.05
0.18
1.3
1.5
0.36
0.48
nmol/l
1.40
92
881
12
143
0.84
0.18
2.3
1.3
1552.29
3680.97
e6/l
—
7
100
45
415
1.09
0.18
1.9
2.3
16.94
16.71
%
0.13
20
209
511
5014
1.02
0.17
1.7
1.8
—
—
—
0
0
44
407
1.08
0.17
4.5
7.8
105.18
105.44
mmol/l
0.11
38
365
128
1334
0.96
0.17
2.1
2.0
11.98
5.11
ug/l
1.16
112
1178
8
68
1.18
0.16
1.1
1.1
—
—
—
0
0
35
321
1.09
0.16
1.1
1.2
—
—
—
0
0
69
652
1.06
0.16
1.1
1.1
1.67
3.38
u/ml
1.97
37
343
8
73
1.10
0.15
1.1
1.1
—
—
—
0
0
10
119
0.84
0.15
1.8
1.4
—
—
—
0
0
9
79
1.14
0.15
1.0
1.5
—
—
—
0
0
9
79
1.14
0.15
1.0
1.5
—
—
—
0
0
14
121
1.16
0.15
1.1
1.0
—
—
—
0
0
13
112
1.16
0.14
1.2
1.2
—
—
—
0
0
77
733
1.05
0.14
1.2
1.4
992.72
6175.33
e6/l
0.51
61
588
14
160
0.87
0.14
1.1
1.0
—
—
—
0
0
11
128
0.86
0.13
1.1
1.2
—
—
—
0
0
17
151
1.13
0.13
1.3
1.6
120.94
127.89
nmol/l
0.34
17
151
267
2611
1.02
0.13
3.1
2.9
34.32
39.24
u/ml
0.22
257
2527
64
608
1.05
0.13
1.1
1.1
—
—
—
0
0
63
599
1.05
0.12
1.1
1.1
0.04
0.35
u/ml
0.76
16
147
46
487
0.94
0.12
2.4
2.5
0.82
0.82
nmol/l
0.00
37
413
93
964
0.96
0.11
1.2
1.1
—
—
—
0
0
57
598
0.95
0.11
2.2
1.9
5.34
5.28
mmol/24h
0.05
52
541
13
146
0.89
0.10
2.3
1.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
50
476
1.05
0.10
3.5
3.9
0.39
0.36
u/ml
0.29
27
263
235
2306
1.02
0.10
1.4
1.6
—
—
—
0
0
59
565
1.04
0.09
3.4
3.6
30.72
22.01
mg/l
0.80
36
347
76
733
1.04
0.09
1.2
1.3
3.31
20.85
e6/l
4.24
55
555
5
47
1.06
0.09
1.6
1.2
79.80
84.34
ng/l
—
5
47
177
1808
0.98
0.09
10.3
7.4
95.88
96.27
%
0.28
169
1745
381
3861
0.99
0.09
1.5
1.7
—
—
—
0
0
28
262
1.07
0.09
2.6
2.6
—
—
—
0
0
94
969
0.97
0.09
1.2
1.1
—
—
—
0
0
24
257
0.93
0.08
1.2
1.2
—
55.57
—
0
14
5
62
0.81
0.08
1.2
1.6
—
—
—
0
0
16
146
1.10
0.08
1.1
1.3
68.45
85.23
nmol/24h
0.69
16
146
7
64
1.09
0.08
1.1
1.1
—
—
—
0
0
10
88
1.14
0.08
1.5
3.1
—
—
—
0
0
10
88
1.14
0.08
1.1
1.0
64.74
75.60
ug/l
—
10
76
7
65
1.08
0.08
1.1
1.2
—
—
—
0
0
7
68
1.03
0.07
1.1
1.3
—
—
—
0
0
8
77
1.04
0.07
1.1
1.1
—
—
—
0
0
16
147
1.09
0.07
1.6
1.5
—
—
—
0
0
9
86
1.05
0.07
1.0
1.0
—
—
—
0
0
9
86
1.05
0.07
1.0
1.1
—
—
—
0
0
22
206
1.07
0.07
1.1
1.1
—
—
—
0
0
238
2348
1.01
0.06
1.4
1.6
—
—
—
0
0
23
244
0.94
0.06
1.0
1.1
1.00
1.04
u/l
0.43
11
104
23
244
0.94
0.06
4.5
6.6
6.84
6.91
mmol/l
0.03
16
204
29
276
1.05
0.06
1.8
1.9
—
—
—
0
0
11
121
0.91
0.06
2.5
1.4
4733.00
81884.59
e6/l
—
5
68
67
652
1.03
0.05
2.7
2.0
1.05
2.28
ug/l
0.87
59
587
170
1679
1.01
0.04
3.7
3.4
5.78
5.82
kpa
0.20
165
1622
16
150
1.07
0.04
1.1
1.1
17.07
13.03
u/ml
—
9
102
18
171
1.05
0.03
1.2
1.1
—
—
—
0
0
11
102
1.08
0.03
1.7
1.8
—
—
—
0
0
11
102
1.08
0.03
1.7
1.8
—
—
—
0
0
11
102
1.08
0.03
1.7
1.8
—
—
—
0
0
11
102
1.08
0.03
1.0
1.1
—
—
—
0
0
14
132
1.06
0.02
1.5
1.3
5.78
6.37
mmol/l
0.66
14
121
74
730
1.01
0.02
4.2
2.8
25.06
24.84
mmol/l
0.30
65
678
47
479
0.98
0.02
3.9
3.8
22.46
46.29
mg/l
1.09
38
391
10
93
1.08
0.02
1.1
2.1
—
—
—
0
0
41
402
1.02
0.01
1.1
1.2
—
—
—
0
0
25
244
1.02
0.00
1.1
1.1
—
—
—
0
0
453
4523
1.00
0.00
2.4
2.5
2.43
2.43
mmol/l
0.40
388
3957
11
108
1.02
0.00
1.2
1.1
—
—
—
0
0
20
202
0.99
0.00
2.0
1.4
4818.21
51442.77
e6/l
0.80
14
137
48
478
1.00
0.00
3.8
3.8
31.85
43.76
mg/l
0.63
38
392
23
235
0.98
0.00
1.1
1.1
1702.70
1533.25
miu/ml
0.36
23
235
16
159
1.01
0.00
3.3
4.0
—
—
—
0
0
21
209
1.00
0.00
1.4
1.7
1.02
1.19
promille
0.22
15
162
27
274
0.99
0.00
1.6
1.3
—
—
—
0
0
14
144
0.97
0.00
2.2
1.4
37.14
34.68
g/l
0.34
14
132
167
1669
1.00
0.00
3.7
3.4
1.53
1.82
mmol/l
0.45
137
1425
43
433
0.99
0.00
3.2
4.5
34.23
74.87
u/ml
—
9
137
0
6
0.00
0.00
0.0
1.0
—
3.17
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
5.7
—
—
—
0
0
6
64
0.94
-0.00
1.2
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
84
0.95
-0.00
1.1
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
84
0.95
-0.00
1.1
1.1
—
—
—
0
0
9
92
0.98
-0.00
1.2
1.5
8.34
7.95
ug/l
—
9
92
5
53
0.94
-0.00
1.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.5
—
—
—
0
0
9
90
1.00
-0.00
1.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint O15_ICP_WIDE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| O15_ICP_WIDE | 0.645 [0.51, 0.82] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.15 |
During the follow-up period (1.1.1998 — 31.12.2019), 78 out of 13316 females with O15_ICP_WIDE died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have O15_ICP_WIDE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.056% | No data |
| 5 | 0.347% | No data |
| 10 | 0.859% | No data |
| 15 | 1.645% | No data |
| 20 | 2.956% | No data |
Relationships between endpoints
↥Index endpoint: O15_ICP_WIDE – Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8
GWS hits: 32
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data