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Twin gestation

Endpoint Browser PheWeb

O15_TWIN_GEST

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — O30.0
  • Hospital discharge: ICD-9 — 6510
  • Hospital discharge: ICD-8 — Y8[1-3]
  • Cause of death: ICD-10 — O30.0
  • Cause of death: ICD-9 — 6510
  • Cause of death: ICD-8 — Y8[1-3]

2 out of 7 registries used, show all original rules.

3942

4. Check minimum number of events

None

3942

5. Include endpoints

None

3942

6. Filter based on genotype QC (FinnGen only)

3942

Control definitions (FinnGen only)

Control exclude
O15_MATERN_CARE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF6v3

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 27717 27717 -
Only index persons 27401 27401 -
Unadjusted period prevalence (%)
Whole population 0.79 0.79 -
Only index persons 1.01 1.01 -
Median age at first event (years)
Whole population - 30.85 -
Only index persons - 30.85 -

-FinnGen-

Key figures

All Female Male
Number of individuals 3942 3942 -
Unadjusted period prevalence (%) 1.34 1.34 -
Median age at first event (years) 31.12 31.12 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3563
Matched controls
35629
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
29.9
323.0
1086
515
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
5.2
323.0
1282
3483
Z37.2
ICD-10 Finland
Twins, both liveborn
1829.8
323.0
322
*
6510A
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, RASKAUDEN AIKANA]
+∞
323.0
454
*
O30.00
ICD-10 Finland
Twin pregnancy with separate amniotic and chorionic sacs
+∞
323.0
488
*
O84.2
ICD-10 Finland
Multiple delivery, all by caesarean section
930.7
323.0
484
6
O30.0
ICD-10 Finland
Twin pregnancy
16384.0
323.0
2267
*
O32.1
ICD-10 Finland
Maternal care for breech presentation
655.3
323.0
459
8
6510B
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, SYNNYTYKSEN AIKANA]
+∞
323.0
681
*
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
18.2
323.0
1393
1214
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
9.2
323.0
906
1273
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
5604.1
323.0
496
*
O60
ICD-10 Finland
Preterm labour and delivery
30.8
323.0
528
200
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
1671.9
323.0
678
5
O84.8
ICD-10 Finland
Other multiple delivery
3124.9
312.9
298
*
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
619.2
292.4
286
5
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
2568.4
261.5
250
*
O82.0
ICD-10 Finland
Delivery by elective caesarean section
16.8
260.7
431
290
W84
ICPC
Pregnancy high risk
10.7
221.5
450
473
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
3.2
220.0
1673
7678
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
3.6
209.6
1193
4359
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
8.3
202.0
478
652
Z39.2
ICD-10 Finland
Routine postpartum follow-up
3.7
187.1
975
3262
O30.01
ICD-10 Finland
Twin pregnancy with a shared chorionic sac and a separate amniotic sac
+∞
174.4
166
*
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
4.6
173.0
678
1733
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
326.9
154.0
155
5
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
7.5
150.1
375
547
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
+∞
142.7
136
*
G03GA01
ATC
chorionic gonadotrophin; parenteral
4.7
142.2
532
1278
G03DA04
ATC
progesterone; systemic, rectal, vaginal
5.5
136.9
437
879
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
+∞
134.2
128
*
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
667.2
131.4
129
*
O64.1
ICD-10 Finland
Obstructed labour due to breech presentation
25.2
131.3
187
78
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
4.1
126.8
559
1563
SPAT1379
SPAT
Health check-up of pregnant person
3.4
124.4
708
2442
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
3.6
121.2
625
1993
O47.1
ICD-10 Finland
False labour at or after 37 completed weeks of gestation
103.8
118.8
130
13
XMA22
NOMESCO Finland
General examination of pregnant woman
4.1
112.4
488
1336
MAG00
NOMESCO Finland
Assisted breech delivery
53.5
111.8
134
26
SPAT1197
SPAT
Extensive health check-up of expecting family
2.9
108.5
782
3148
O34.3
ICD-10 Finland
Maternal care for cervical incompetence
+∞
105.7
101
*
G03GA06
ATC
follitropin beta; parenteral
5.1
105.7
356
753
SPAT1380
SPAT
Postpartum check-up
3.3
99.6
580
2005
8811
FHL
Cesarean section
3.9
98.8
447
1262
O68.0
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly
4.2
97.8
401
1035
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
246.5
94.0
96
*
Z32.1
ICD-10 Finland
Pregnancy confirmed
2.9
93.0
639
2467
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
2.8
92.0
710
2947
6440B
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS]
10.7
91.4
182
178
W78
ICPC
Pregnancy
2.5
91.2
843
3881
O48
ICD-10 Finland
Prolonged pregnancy
900.6
90.2
88
*
O41.0
ICD-10 Finland
Oligohydramnios
879.6
88.1
86
*
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
858.6
86.0
84
*
H01CA02
ATC
nafarelin; nasal
4.3
83.3
337
854
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
3.9
83.2
376
1054
G03GA02
ATC
human menopausal gonadotrophin; parenteral
4.4
81.2
314
761
O20.0
ICD-10 Finland
Threatened abortion
5.6
75.8
234
444
O42.1
ICD-10 Finland
Premature rupture of membranes, onset of labour after 24 hours
+∞
75.3
72
*
WX320
NOMESCO Finland
Spinalanesthesy
2.5
73.4
680
3089
O40
ICD-10 Finland
Polyhydramnios
+∞
73.2
70
*
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
6.0
69.1
199
346
MAA00
NOMESCO Finland
Amniocentesis
8.2
68.3
158
201
WX306
NOMESCO Finland
Lumbar epidural anesthesy
3.1
68.0
411
1435
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
2.6
67.2
539
2252
O35.9
ICD-10 Finland
Maternal care for (suspected) fetal abnormality and damage, unspecified
+∞
66.9
64
*
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
8.3
66.4
152
190
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
5.0
64.3
217
455
SPAT1196
SPAT
Monitoring of normal pregnancy
3.0
64.2
415
1513
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
6.6
63.7
171
271
L02AE01
ATC
buserelin; implant, nasal, parenteral
6.0
61.1
176
306
6440A
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS IMMINENS]
5.3
59.6
190
373
W92
ICPC
Compl labour/ delivery livebirth
7.9
59.3
140
184
O47.9
ICD-10 Finland
False labour, unspecified
14.9
59.0
100
69
N97.9
ICD-10 Finland
Female infertility, unspecified
2.6
58.0
481
2035
O80.1
ICD-10 Finland
Spontaneous breech delivery
19.4
56.7
87
46
G03GA05
ATC
follitropin alfa; parenteral
3.5
55.8
282
858
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
2.4
55.5
512
2292
6522B
ICD-9 Finland
Malposition and malpresentation of foetus, Breech presentation without mention of version[PRAESENTATIO CLUNIUM,SYNNYTYKSEN AIKANA]
5.4
54.0
170
329
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
4.1
53.5
218
552
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
3.2
52.5
303
1017
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.6
52.5
418
1721
G03GB02
ATC
clomifene; oral
3.8
52.1
231
631
O41.1
ICD-10 Finland
Infection of amniotic sac and membranes
+∞
51.2
49
*
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
5.8
50.0
147
262
O36.4
ICD-10 Finland
Maternal care for intrauterine death
+∞
49.1
47
*
N97.0
ICD-10 Finland
Female infertility associated with anovulation
4.1
48.9
203
522
O44.0
ICD-10 Finland
Placenta praevia specified as without haemorrhage
+∞
45.9
44
*
O82.11
ICD-10 Finland
Childbirth with an emergency caesarean section in an emergency
8.7
45.1
99
116
O44.1
ICD-10 Finland
Placenta praevia with haemorrhage
+∞
43.8
42
*
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
5.9
42.4
122
212
NE1AG
NOMESCO Finland
MRI pelvimetry with high intensity magnet
148.4
41.8
44
*
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
12.3
41.6
76
63
O02.1
ICD-10 Finland
Missed abortion
2.5
41.6
349
1473
W85
ICPC
Gestational diabetes
3.3
41.0
219
694
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
5.4
40.9
126
238
O14.1
ICD-10 Finland
Severe pre-eclampsia
8.0
39.5
91
116
SPAT1357
SPAT
Monitoring of problem during pregnancy
3.9
39.1
166
436
O83.0
ICD-10 Finland
Breech extraction
44.2
39.1
48
11
O32.2
ICD-10 Finland
Maternal care for transverse and oblique lie
74.4
39.0
44
6
O84.1
ICD-10 Finland
Multiple delivery, all by forceps and vacuum extractor
87.1
38.8
43
5
6581A
ICD-9 Finland
Other problems associated with amniotic cavity and membranes, Premature rupture of membranes
+∞
38.6
37
*
6441A
ICD-9 Finland
Early or threatened labour, Other threatened labour
+∞
38.6
37
*
WX307
NOMESCO Finland
Obstetric epidural analgesia
2.2
38.1
422
2042
Z39.1
ICD-10 Finland
Care and examination of lactating mother
4.5
37.6
138
316
O30.9
ICD-10 Finland
Multiple gestation, unspecified
+∞
36.5
35
*
O43.0
ICD-10 Finland
Placental transfusion syndromes
+∞
36.5
35
*
O36.9
ICD-10 Finland
Maternal care for fetal problem, unspecified
360.9
36.0
36
*
MAC96
NOMESCO Finland
Other induction or advancement of labour
3.9
35.7
153
405
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.6
35.7
1507
11295
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
5.5
34.5
104
192
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
5.0
34.1
113
233
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
3.1
33.8
198
668
O31.8
ICD-10 Finland
Other complications specific to multiple gestation
+∞
33.4
32
*
O99.80
ICD-10 Finland
The fear of childbirth
2.7
32.8
237
915
H01CC01
ATC
ganirelix; parenteral
2.9
32.6
204
721
O63.0
ICD-10 Finland
Prolonged first stage (of labour)
5.0
32.5
107
219
O32.0
ICD-10 Finland
Maternal care for unstable lie
+∞
32.3
31
*
O69.0
ICD-10 Finland
Labour and delivery complicated by prolapse of cord
40.5
32.1
40
10
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
1.9
31.9
531
3016
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
2.9
31.6
202
722
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
1.8
31.2
672
4159
MAB20
NOMESCO Finland
Failed external version
60.6
31.1
36
6
O61.0
ICD-10 Finland
Failed medical induction of labour
8.3
30.7
69
85
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
5.4
30.6
94
178
MA4AT
NOMESCO Finland
Chorion biopsy with ultrasound guidance
51.9
30.3
36
7
6582B
ICD-9 Finland
Other problems associated with amniotic cavity and membranes, Delayed delivery after spontaneous or unspecified rupture of membranes
+∞
30.2
29
*
6526B
ICD-9 Finland
Malposition and malpresentation of foetus, Multiple gestation with malpresentation of one foetus or more[MONISIKIÖN YHT ESIINT VIRHETARJ,SYNNYTYKSEN AIKANA]
156.3
29.7
31
*
W90
ICPC
Uncompl labour/delivery livebirth
2.7
29.5
211
809
SPAT1189
SPAT
Other ultrasound examination during pregnancy
3.2
29.5
163
530
O31.2
ICD-10 Finland
Continuing pregnancy after intrauterine death of one fetus or more
+∞
29.2
28
*
G03GA04
ATC
urofollitropin; parenteral
5.4
29.1
89
168
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
3.4
29.1
144
431
MAX99
NOMESCO Finland
Assistance to normal delivery
1.9
29.0
490
2794
MAE00
NOMESCO Finland
Outlet vacuum delivery
2.2
28.6
303
1432
O45.9
ICD-10 Finland
Premature separation of placenta, unspecified
+∞
28.2
27
*
O80.8
ICD-10 Finland
Other single spontaneous delivery
2.9
27.5
170
597
O36.3
ICD-10 Finland
Maternal care for signs of fetal hypoxia
+∞
27.1
26
*
LGA20
NOMESCO Finland
Sterilisation by constriction of Fallopian tubes
6.2
27.1
74
122
B01AB05
ATC
enoxaparin; parenteral
1.6
26.7
745
4944
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
4.0
26.4
109
281
O30.1
ICD-10 Finland
Triplet pregnancy
+∞
26.1
25
*
O46.8
ICD-10 Finland
Other antepartum haemorrhage
+∞
26.1
25
*
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
4.2
26.0
100
241
LCA30
NOMESCO Finland
Transfer of oocyte or embryo to uterus in assisted fertilisation
6.9
25.8
65
96
O34.1
ICD-10 Finland
Maternal care for tumour of corpus uteri
262.5
25.7
26
*
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
2.6
25.1
193
774
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
3.7
25.1
112
309
O42.2
ICD-10 Finland
Premature rupture of membranes, labour delayed by therapy
+∞
25.0
24
*
LGA10
NOMESCO Finland
Sterilisation by destruction or division of Fallopian tubes
6.6
24.6
64
99
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
8.7
24.5
53
62
O32.5
ICD-10 Finland
Maternal care for multiple gestation with malpresentation of one fetus or more
+∞
24.0
23
*
O64.8
ICD-10 Finland
Obstructed labour due to other malposition and malpresentation
8.5
23.8
52
62
FM1QE
NOMESCO Finland
Extensive ultrasound of fetal heart
10.1
23.7
47
47
L02AE02
ATC
leuprorelin; implant, parenteral
3.1
23.4
130
425
G02CB01
ATC
bromocriptine; systemic
3.1
23.1
128
418
N97.4
ICD-10 Finland
Female infertility associated with male factors
2.9
22.8
146
523
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.0
22.7
290
1482
MAG10
NOMESCO Finland
Breech extraction delivery
231.4
22.6
23
*
O81.4
ICD-10 Finland
Vacuum extractor delivery
2.0
22.6
322
1718
8803
FHL
Stern exit
8.3
22.6
50
61
O86.0
ICD-10 Finland
Infection of obstetric surgical wound
6.2
22.2
60
98
Z30.2
ICD-10 Finland
Sterilization
1.7
22.2
538
3414
O72.0
ICD-10 Finland
Third-stage haemorrhage
3.0
22.1
133
460
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
2.2
22.0
228
1062
O36.0
ICD-10 Finland
Maternal care for rhesus isoimmunization
+∞
21.9
21
*
TLW00
NOMESCO Finland
Insemination
2.9
21.7
137
489
O21.0
ICD-10 Finland
Mild hyperemesis gravidarum
4.9
21.5
71
148
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
3.1
21.4
118
385
SPAT1200
SPAT
Guidance for breast-feeding and breast care
3.1
21.3
119
392
W29
ICPC
Pregnancy symptom/complaint other
3.2
21.2
116
376
O28.3
ICD-10 Finland
Abnormal ultrasonic finding on antenatal screening of mother
8.2
21.1
47
58
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
4.1
20.5
81
202
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
3.5
20.4
96
278
TLW10
NOMESCO Finland
Transfer of fresh embryo
2.9
20.4
125
438
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
4.8
20.0
67
142
N98.1
ICD-10 Finland
Hyperstimulation of ovaries
6.1
19.9
54
89
A05AA02
ATC
ursodeoxycholic acid; oral
3.8
19.9
85
227
O30.02
ICD-10 Finland
Twin pregnancy with a shared amniotic and chorionic sac
+∞
19.8
19
*
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
4.2
19.8
76
185
O83.1
ICD-10 Finland
Other assisted breech delivery
201.0
19.6
20
*
MWE00
NOMESCO Finland
Reoperation for deep haemorrhage in obstetric surgery
40.3
19.5
24
6
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
3.0
19.3
116
399
6467A
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Liver disorders in pregnancy[HEPATOSIS GRAVIDARUM]
5.6
19.3
56
101
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
2.7
19.2
134
509
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
5.2
18.9
58
112
Z36.8
ICD-10 Finland
Other antenatal screening
3.0
18.8
113
389
6289A
ICD-9 Finland
Infertility, female, Of unspecified origin[STERILITAS ET INFERTILITAS MULIERIS NUD PRIM]
4.3
18.7
70
166
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
3.1
18.7
103
337
G03DB01
ATC
dydrogesterone; oral
1.5
18.6
699
4933
Z31.2
ICD-10 Finland
In vitrofertilization
4.4
18.6
68
158
QBJ30
NOMESCO Finland
Correction of abdominal apron
4.2
18.6
71
172
FM1NE
NOMESCO Finland
Ultrasound examination of fetal heart
20.9
18.6
27
13
O26.7
ICD-10 Finland
Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
5.1
18.2
57
113
6400A
ICD-9 Finland
Haemorrhage in early pregnancy, Threatened abortion
4.1
17.8
69
170
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
2.5
17.8
137
552
6282B
ICD-9 Finland
Infertility, female, Of tubal origin[STERIL ET INFERT EX ORIG TUBAE UTERINAE SEC]
8.5
17.6
38
45
TLW12
NOMESCO Finland
Insertion of frozen embryo
3.0
17.5
101
341
Z35.1
ICD-10 Finland
Supervision of pregnancy with history of abortive outcome
8.0
17.5
39
49
C08CA05
ATC
nifedipine; systemic
2.5
16.9
134
546
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
2.2
16.8
167
765
SPAT1391
SPAT
Counselling and guidance related to family situation
4.4
16.5
59
135
SPAT1246
SPAT
Screening of depression or other psychiatric problem
2.1
15.9
190
947
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.5
15.7
513
3494
O34.0
ICD-10 Finland
Maternal care for congenital malformation of uterus
+∞
15.6
15
*
MAB00
NOMESCO Finland
Cerclage of cervix of pregnant uterus
160.7
15.5
16
*
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
2.2
15.2
157
732
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.5
15.2
560
3919
J01DA01
ATC
[U] cefalexin; systemic
1.3
14.9
2115
18650
O10.0
ICD-10 Finland
Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
2.9
14.9
91
319
SPAT1373
SPAT
Combined screening in early pregnancy
3.6
14.8
67
190
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
2.9
14.7
88
307
O35.0
ICD-10 Finland
Maternal care for (suspected) central nervous system malformation in fetus
+∞
14.6
14
*
6570A
ICD-9 Finland
Polyhydramnios[POLYHYDRAMNION, RASKAUDEN AIKANA]
+∞
14.6
14
*
O64.4
ICD-10 Finland
Obstructed labour due to shoulder presentation
80.4
14.6
16
*
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
2.0
14.3
174
874
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
14.2
907
7056
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.3
14.1
1170
9497
N02BE01
ATC
paracetamol; systemic, rectal
1.4
14.1
2793
25806
WX290
NOMESCO Finland
Other blockade of nerve
1.3
14.0
1695
14541
Z36.4
ICD-10 Finland
Antenatal screening for fetal growth retardation using ultrasound and other physical methods
3.0
14.0
82
282
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
13.8
1178
9595
SPAT1263
SPAT
Sampling
1.3
13.8
1237
10153
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
4.4
13.5
48
110
O31.1
ICD-10 Finland
Continuing pregnancy after abortion of one fetus or more
140.5
13.5
14
*
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
2.2
13.3
133
613
O47
ICD-10 Finland
False labour
5.4
13.0
38
71
1413
FHL
Laparoscopy and other therapeutic procedure
2.5
12.8
102
421
O21
ICD-10 Finland
Excessive vomiting in pregnancy
4.7
12.7
42
90
O20.8
ICD-10 Finland
Other haemorrhage in early pregnancy
5.3
12.5
37
70
N97.1
ICD-10 Finland
Female infertility of tubal origin
2.9
12.5
75
263
MAB10
NOMESCO Finland
External version
17.4
12.5
19
11
N97.8
ICD-10 Finland
Female infertility of other origin
2.2
12.4
120
545
SPAT1190
SPAT
Insertion or removal of intrauterine contraceptive device
1.6
12.4
317
2025
SPAT1316
SPAT
Extensive health check-up of children and adolescents
2.2
12.4
125
579
LAA06
NOMESCO Finland
Transvaginal puncture of ovarian cyst
3.5
12.2
56
162
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
4.4
11.8
41
93
XLA10
NOMESCO Finland
NA
1.8
11.8
221
1296
Z31.5
ICD-10 Finland
Genetic counselling
1.8
11.8
201
1144
Z29
ICPC
Social problem NOS
3.1
11.7
63
206
SPAT1375
SPAT
Structural ultrasound screening, weeks 18+0-21+6
4.2
11.7
43
103
P01AB01
ATC
metronidazole; oral, rectal
1.3
11.6
1380
11702
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
11.5
830
6546
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
3.9
11.5
46
119
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
0.5
11.5
82
1649
6412B
ICD-9 Finland
Antepartum haemorrhage, abruptio placentae and placenta praevia, Premature separation of placenta[ABLATIO PLACENTAE ANTETEMPUS,SYNN PÄÄTT HOITOJAKSO]
+∞
11.5
11
*
O33.9
ICD-10 Finland
Maternal care for disproportion, unspecified
+∞
11.5
11
*
O43.8
ICD-10 Finland
Other placental disorders
+∞
11.5
11
*
ULC02
NOMESCO Finland
Hysteroscopy
1.8
11.4
212
1241
J01DB01
ATC
cefalexin; oral
1.3
11.3
2723
25301
8216
FHL
Applicatio ovii
15.1
11.3
18
12
O12.1
ICD-10 Finland
Gestational proteinuria
4.1
11.3
43
107
WX810
NOMESCO Finland
Neonatal intesive care
10.6
11.2
21
20
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
3.5
11.1
50
143
LBF01
NOMESCO Finland
Laparoscopic perfusion of Fallopian tube
2.4
11.1
95
408
SPAT1303
SPAT
Counselling and guidance related to growth and development
4.1
10.9
41
101
O99.5
ICD-10 Finland
Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
3.8
10.8
44
116
SPAT1187
SPAT
General ultrasound examination in early pregnancy
3.8
10.8
45
121
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
10.7
246
1528
WYA40
NOMESCO Finland
Assessment of oral health and treatment needs for family expecting first child
2.7
10.7
72
272
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
10.7
2507
23088
O12.0
ICD-10 Finland
Gestational oedema
5.0
10.6
33
67
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
4.4
10.6
37
85
W05
ICPC
Pregnancy vomiting/nausea
3.9
10.5
42
109
6418A
ICD-9 Finland
Antepartum haemorrhage, abruptio placentae and placenta praevia, Other antepartum haemorrhage[ALIA HAEMORRHAGIA IN GRAVIDITATE,HOITOJ ENNEN SYNN]
+∞
10.4
10
*
6419A
ICD-9 Finland
Antepartum haemorrhage, abruptio placentae and placenta praevia, Unspecified antepartum haemorrhage[HAEMORRHAGIA NUD IN GRAVIDITATE,HOITOJ ENN SYNN NUD]
+∞
10.4
10
*
O33.5
ICD-10 Finland
Maternal care for disproportion due to unusually large fetus
+∞
10.4
10
*
O30
ICD-10 Finland
Multiple gestation
+∞
10.4
10
*
O35.5
ICD-10 Finland
Maternal care for (suspected) damage to fetus by drugs
+∞
10.4
10
*
O35.2
ICD-10 Finland
Maternal care for (suspected) hereditary disease in fetus
+∞
10.4
10
*
O34.4
ICD-10 Finland
Maternal care for other abnormalities of cervix
+∞
10.4
10
*
O84.9
ICD-10 Finland
Multiple delivery, unspecified
+∞
10.4
10
*
MBA05
NOMESCO Finland
Curettage of uterus after abortion
3.4
10.4
48
141
J01CA08
ATC
pivmecillinam; oral
1.3
10.4
1634
14293
M62.0
ICD-10 Finland
Diastasis of muscle
8.2
10.3
22
27
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
1.4
10.0
460
3351
L02BG04
ATC
letrozole; oral
1.7
9.8
192
1141
8219
FHL
Other measure in this category
8.7
9.8
20
23
O64.0
ICD-10 Finland
Obstructed labour due to incomplete rotation of fetal head
2.4
9.8
80
338
O62.2
ICD-10 Finland
Other uterine inertia
5.3
9.6
28
53
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
2.1
9.6
106
515
W30
ICPC
Pregnancy, Medical examin/health eval complete
4.5
9.5
32
71
A02BC01
ATC
omeprazole; systemic
1.3
9.5
641
4986
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.6
9.4
259
1690
O33.1
ICD-10 Finland
Maternal care for disproportion due to generally contracted pelvis
+∞
9.4
9
*
O41.8
ICD-10 Finland
Other specified disorders of amniotic fluid and membranes
+∞
9.4
9
*
O63.2
ICD-10 Finland
Delayed delivery of second twin, triplet, etc.
+∞
9.4
9
*
O85
ICD-10 Finland
Puerperal sepsis
3.2
9.3
46
144
1410
FHL
Laparoscopy
2.0
9.2
109
546
G02BA03
ATC
plastic IUD with progestogen
1.3
9.0
725
5785
SPAT1315
SPAT
Periodic health check-up of children and adolescents
2.0
9.0
116
597
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
2.2
9.0
91
424
MBA04
NOMESCO Finland
Curettage of uterus after delivery
4.0
9.0
34
85
L02AE03
ATC
goserelin; implant
2.7
9.0
61
232
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
1.6
8.9
245
1597
8221
FHL
Sterilization of the laparotomy pathway
2.2
8.9
83
374
MA3AE
NOMESCO Finland
Combined first trimester screening
1.8
8.9
149
845
6523B
ICD-9 Finland
Malposition and malpresentation of foetus, Transverse or oblique presentation[SITUS TRANSVERSUS ET OBLIQUUS,SYNNYTYKSEN AIKANA]
12.5
8.9
15
12
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
8.8
1638
14508
O73.0
ICD-10 Finland
Retained placenta without haemorrhage
3.1
8.8
46
150
F43.00
ICD-10 Finland
Acute stress reaction mild
1.9
8.7
116
607
MAE03
NOMESCO Finland
Mid-cavity or high vacuum delivery
4.7
8.7
28
60
SPAT1383
SPAT
Extensive health check-up at 4 years of age
3.3
8.7
41
124
SPAT1325
SPAT
Vaccination
1.3
8.6
663
5254
6522A
ICD-9 Finland
Malposition and malpresentation of foetus, Breech presentation without mention of version[PRAESENTATIO CLUNIUM,RASKAUDEN AIKANA]
3.5
8.5
37
105
O91.2
ICD-10 Finland
Nonpurulent mastitis associated with childbirth
3.0
8.5
47
160
O69.8
ICD-10 Finland
Labour and delivery complicated by other cord complications
20.1
8.5
12
6
MBC10
NOMESCO Finland
Repair of obstetric laceration of vagina
2.3
8.5
75
332
WX600
NOMESCO Finland
Single shot through catheter
2.4
8.4
66
275
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
1.3
8.4
621
4894
O36.2
ICD-10 Finland
Maternal care for hydrops fetalis
+∞
8.3
8
*
O33.3
ICD-10 Finland
Maternal care for disproportion due to outlet contraction of pelvis
+∞
8.3
8
*
O30.8
ICD-10 Finland
Other multiple gestation
+∞
8.3
8
*
MAA54
NOMESCO Finland
Fetoscopy
+∞
8.3
8
*
6584B
ICD-9 Finland
Other problems associated with amniotic cavity and membranes, Infection of amniotic cavity[AMNIONITIS, SYNNYTYKSEN AIKANA]
+∞
8.3
8
*
O45.8
ICD-10 Finland
Other premature separation of placenta
+∞
8.3
8
*
6500B
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
0.8
8.3
593
7375
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.5
8.2
325
2298
JAF10
NOMESCO Finland
Repair of umbilical hernia
2.7
8.2
52
191
O86.1
ICD-10 Finland
Other infection of genital tract following delivery
3.6
8.1
34
94
SPAT1381
SPAT
Extensive health check-up at 4 months of age
4.5
8.0
27
61
Z31.1
ICD-10 Finland
Artificial insemination
3.6
8.0
34
95
O03.0
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by genital tract and pelvic infection
3.3
8.0
38
116
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
8.0
1986
18064
6282A
ICD-9 Finland
Infertility, female, Of tubal origin[STERIL ET INFERT EX ORIG TUBAE UTERINAE PRIM]
5.5
8.0
22
40
W03
ICPC
Antepartum bleeding
3.5
7.9
35
101
G03DC02
ATC
norethisterone; oral
1.4
7.9
325
2315
E66.9
ICD-10 Finland
Obesity, unspecified
1.9
7.7
114
619
F20.9
ICD-10 Finland
Schizophrenia, unspecified
0.2
7.7
6
344
M01AE01
ATC
ibuprofen; systemic, rectal
1.4
7.7
3208
30925
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.5
7.7
58
238
O99.7
ICD-10 Finland
Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
5.9
7.7
20
34
MA3AE
SPAT
NA
7.4
7.7
17
23
SGA01
NOMESCO Finland
Tooth opening as first aid
1.3
7.6
543
4249
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
7.6
2276
21051
LA2JE
NOMESCO Finland
Follow-up of menstrual cycle with repeated measurement of ovarian cyst
3.1
7.6
39
127
Z30.0
ICD-10 Finland
General counselling and advice on contraception
1.4
7.6
300
2126
SPAT1382
SPAT
Extensive health check-up at 18 months of age
4.0
7.5
28
70
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
1.7
7.5
143
846
MBC30
NOMESCO Finland
Repair of partial rupture of perineum
2.1
7.4
82
400
KAY40
NOMESCO Finland
NA
0.4
7.4
24
641
F29
ICD-10 Finland
Unspecified nonorganic psychosis
0.4
7.4
39
863
MCA00
NOMESCO Finland
Upper uterine segment caesarean section
13.4
7.4
12
9
O62.1
ICD-10 Finland
Secondary uterine inertia
2.9
7.3
43
152
SPAT1301
SPAT
No procedures
1.3
7.3
730
5984
TMA00
NOMESCO Finland
Episiotomy
1.7
7.3
150
909
O34.8
ICD-10 Finland
Maternal care for other abnormalities of pelvic organs
+∞
7.3
7
*
O36.1
ICD-10 Finland
Maternal care for other isoimmunization
+∞
7.3
7
*
W18
ICPC
Post-partum symptom/complaint other
4.5
7.2
24
54
W28
ICPC
Limited function/disability (W)
7.3
7.2
16
22
6565A
ICD-9 Finland
Other foetal and placental problems affecting management of mother, Poor foetal growth[SIKIÖN HIDASTUNUT INTRAUTERIININ KASVU,RASK AIK]
4.1
7.2
26
64
XMA00
NOMESCO Finland
NA
3.7
7.1
29
79
Z39
ICD-10 Finland
Postpartum care and examination
2.6
7.1
47
180
LCH11
NOMESCO Finland
Pharmacologic abortion
1.6
7.1
193
1261
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.4
7.1
371
2769
V230A
ICD-9 Finland
Supervision of high-risk pregnancy, Pregnancy with history of infertility
2.6
7.0
49
191
C07AG01
ATC
labetalol; systemic
2.4
7.0
57
244
WX110
NOMESCO Finland
Local anesthesy
1.2
7.0
2311
21485
O26.9
ICD-10 Finland
Pregnancy-related condition, unspecified
3.7
6.9
28
76
O00.1
ICD-10 Finland
Tubal pregnancy
2.0
6.9
85
434
O90.9
ICD-10 Finland
Complication of the puerperium, unspecified
5.8
6.9
18
31
O62.0
ICD-10 Finland
Primary inadequate contractions
4.2
6.9
24
57
O21.1
ICD-10 Finland
Hyperemesis gravidarum with metabolic disturbance
4.6
6.9
22
48
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
2.2
6.8
64
293
6424A
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Mild or unspecified pre-eclampsia[PRAE-ECLAMPSIA LEVIS, ENNEN SYNNYTYSTÄ]
2.4
6.8
55
235
6563B
ICD-9 Finland
Other foetal and placental problems affecting management of mother, Foetal distress[ASPHYXIA FOETALIS, SYNNYTYKSEN AIKANA]
2.0
6.8
80
404
W99
ICPC
Disorder of pregn/delivery other
5.3
6.8
19
36
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
1.7
6.8
119
691
Z32
ICD-10 Finland
Pregnancy examination and test
2.9
6.7
37
127
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
0.2
6.7
7
334
LGA00
NOMESCO Finland
Sterilisation by ligature of Fallopian tubes
3.9
6.7
25
64
XLA00
NOMESCO Finland
NA
3.7
6.7
27
74
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.6
6.6
150
932
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
0.1
6.6
*
270
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
6.6
1970
18077
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
1.3
6.6
477
3740
O61.1
ICD-10 Finland
Failed instrumental induction of labour
10.0
6.5
12
12
A77
ICPC
Viral disease other/NOS
1.7
6.5
125
743
O73.1
ICD-10 Finland
Retained portions of placenta and membranes, without haemorrhage
3.0
6.5
34
114
O70.1
ICD-10 Finland
Second degree perineal laceration during delivery
1.8
6.4
96
530
P72
ICPC
Schizophrenia
0.2
6.4
7
325
6488A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Abnormal glucose tolerance
2.1
6.4
65
307
SPAT1262
SPAT
Handing over of treatment supplies
1.4
6.4
272
1956
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
1.9
6.4
83
435
N05AX08
ATC
risperidone; systemic
0.6
6.3
69
1221
P22
ICPC
Child behaviour symptom/complaint
5.2
6.3
18
35
O75.7
ICD-10 Finland
Vaginal delivery following previous caesarean section
11.0
6.3
11
10
MBA20
NOMESCO Finland
Expression of placenta
3.5
6.3
27
78
O33.0
ICD-10 Finland
Maternal care for disproportion due to deformity of maternal pelvic bones
+∞
6.2
6
*
63495
ICD-8 Finland
Other complications of pregnancy, Effluxus liquoris amnii praetemporarius
+∞
6.2
6
*
6545A
ICD-9 Finland
Abnormality of organs and soft tissues of pelvis, Cervical incompetence[INSUFFICIENTIA CERVICIS UTERI, RASKAUDEN AIKANA]
+∞
6.2
6
*
O30.2
ICD-10 Finland
Quadruplet pregnancy
+∞
6.2
6
*
Z37.5
ICD-10 Finland
Other multiple births, all liveborn
+∞
6.2
6
*
MAJ00
NOMESCO Finland
Reduction of multiple pregnancy by one foetus
+∞
6.2
6
*
6411B
ICD-9 Finland
Antepartum haemorrhage, abruptio placentae and placenta praevia, Haemorrhage from placenta praevia[PLACENTA PRAEVIA CUM HAEMORRHAGIA,SYNN PÄÄTT HOITOJ]
+∞
6.2
6
*
O34.7
ICD-10 Finland
Maternal care for abnormality of vulva and perineum
+∞
6.2
6
*
O32.8
ICD-10 Finland
Maternal care for other malpresentation of fetus
+∞
6.2
6
*
MAA06
NOMESCO Finland
Amnioreduction
+∞
6.2
6
*
O68.8
ICD-10 Finland
Labour and delivery complicated by other evidence of fetal stress
2.6
6.2
42
164
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
0.7
6.2
252
3405
O22.3
ICD-10 Finland
Deep phlebothrombosis in pregnancy
7.0
6.2
14
20
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.4
6.2
302
2226
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
1.8
6.2
103
588
SAA03
NOMESCO Finland
Extended examination of mouth
1.2
6.2
1250
11040
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
1.4
6.2
280
2038
O67.9
ICD-10 Finland
Intrapartum haemorrhage, unspecified
4.7
6.1
19
41
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
6.1
1123
9832
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
2.2
6.0
58
270
SPAT1392
SPAT
Counselling and guidance related to couple relationship
3.4
6.0
27
81
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
1.3
6.0
497
3969
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
3.0
6.0
31
103

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
199
577
3.58
57.75
2.5
2.0
7.0
5.8
umol/l
0.70
154
438
909
5587
1.81
49.37
1.7
1.6
—
—
—
0
0
1104
7493
1.66
40.74
1.8
1.7
—
—
—
0
0
389
1941
2.11
38.42
1.5
1.3
—
—
—
0
0
673
4174
1.74
34.00
2.2
1.8
—
—
—
0
0
52
114
4.61
22.16
3.2
2.1
—
—
—
0
0
1748
14427
1.38
20.97
4.3
3.5
—
—
—
0
0
101
376
2.73
19.25
1.5
1.4
7.8
7.7
mmol/l
0.23
69
221
1217
9634
1.38
18.14
2.0
2.0
—
—
—
0
0
1149
9126
1.37
16.44
2.1
1.9
—
—
—
0
0
2260
19949
1.31
15.04
3.9
3.5
251.3
1673.5
e6/l
2.58
14
222
437
3018
1.50
13.37
2.4
2.0
8070.7
4434.0
u/l
1.37
185
1089
955
7724
1.31
11.31
2.4
2.2
—
—
—
0
0
844
6750
1.32
10.77
2.0
1.9
—
—
—
0
0
254
1646
1.58
10.36
1.6
1.4
—
—
—
0
0
2343
21282
1.25
10.19
3.9
3.7
—
—
—
0
0
357
2520
1.46
9.73
3.3
3.2
—
—
—
0
0
1722
15178
1.24
9.64
3.8
3.8
6.3
6.3
mmol/l
0.27
1539
14057
144
862
1.70
8.11
1.1
1.1
—
—
—
0
0
968
8130
1.25
8.08
3.9
4.8
1.0
1.1
inr
2.00
351
2736
120
684
1.78
8.04
2.5
1.8
1.1
1.4
g/l
4.04
108
582
892
7444
1.26
7.84
1.8
1.7
1.0
0.8
mg/l
2.95
700
5556
427
3236
1.36
7.71
1.8
2.2
28.5
29.3
s
2.57
410
3130
45
186
2.44
7.16
1.2
1.2
—
—
—
0
0
924
7879
1.23
6.51
3.6
3.2
0.0
0.0
estimate
0.40
390
2852
180
1221
1.50
6.07
1.7
2.0
20.7
20.7
s
0.05
155
1015
1146
10051
1.20
5.95
2.0
1.5
—
—
—
0
0
110
686
1.62
5.42
1.3
1.4
—
—
—
0
0
788
6744
1.21
5.23
2.6
2.7
0.3
0.3
e6/l
0.23
605
4884
3659
35731
1.33
5.15
9.9
9.0
—
—
—
0
0
1699
15541
1.16
5.13
4.4
4.2
0.0
0.0
estimate
1.34
395
2904
38
171
2.23
5.09
1.2
1.2
—
—
—
0
0
187
1328
1.43
5.04
1.7
1.7
—
—
—
0
0
1707
15659
1.16
4.88
3.3
3.0
0.0
0.0
estimate
0.56
396
2832
792
6851
1.20
4.65
2.2
2.0
504.1
2415.7
umol/l
6.47
725
6200
608
5137
1.22
4.57
2.1
2.3
8.8
8.9
e6/l
0.07
536
4457
1683
15479
1.15
4.53
3.3
3.0
0.0
0.0
estimate
0.50
383
2777
230
1724
1.35
4.53
1.3
1.3
—
—
—
0
0
557
4676
1.22
4.46
2.3
2.4
517.3
527.8
mosm/kgh2o
0.43
490
3961
151
1056
1.45
4.46
2.5
2.7
—
—
—
0
0
409
3321
1.26
4.45
1.7
1.6
—
—
—
0
0
75
451
1.68
4.33
2.5
2.5
—
—
—
0
0
423
3485
1.24
4.06
1.8
1.9
—
—
—
0
0
783
6843
1.18
4.04
2.5
2.6
—
—
—
0
0
1972
18451
1.14
3.92
3.1
2.9
71.2
67.9
ug/l
0.23
1885
17715
1527
14073
1.14
3.79
7.6
7.9
0.0
0.0
e9/l
0.75
1294
11533
846
7488
1.17
3.71
2.6
2.7
44.0
79.9
e6/l
1.27
650
5572
3296
32023
1.18
3.56
8.9
9.4
3.9
3.9
mmol/l
1.08
3221
31165
3433
33473
1.20
3.55
10.0
9.8
18.3
17.9
mg/l
0.31
2671
25198
468
3966
1.20
3.42
2.5
2.7
350.9
329.0
ng/l
0.05
218
1974
3281
31898
1.17
3.36
8.9
9.3
139.6
139.6
mmol/l
0.08
3217
31115
146
1088
1.36
3.09
2.0
2.1
3.5
4.5
iu/l
0.69
63
504
94
649
1.46
3.08
1.3
1.4
100.3
108.9
u/ml
0.45
26
138
46
270
1.71
3.01
1.1
1.2
1.0
1.0
ratio
0.37
21
105
1542
14386
1.12
2.92
4.9
5.3
9.4
9.4
umol/l
0.06
1453
13590
960
8717
1.13
2.86
2.2
2.5
58.7
55.8
u/l
0.26
912
8133
1007
9180
1.13
2.81
2.8
2.6
—
—
—
0
0
265
2171
1.24
2.75
1.1
1.1
350.8
151.1
titre
—
6
61
6
10
6.01
2.70
1.5
1.4
—
—
—
0
0
84
585
1.45
2.68
1.9
1.8
—
—
—
0
0
3034
29467
1.13
2.63
11.6
12.1
13.5
13.5
%
0.26
2992
28936
768
6918
1.14
2.58
1.3
1.3
8.4
10.1
u/ml
0.33
346
3068
1059
9738
1.12
2.53
3.0
3.2
67.7
63.8
e6/l
0.10
716
6232
221
1807
1.24
2.37
2.7
2.3
—
—
—
0
0
97
719
1.36
2.22
2.9
3.1
0.5
0.3
g/l
0.41
44
282
62
427
1.46
2.15
1.3
1.2
—
—
—
0
0
11
251
0.44
2.10
1.5
1.5
—
—
—
0
0
26
146
1.79
2.06
2.8
3.0
10.4
8.2
mg/l
0.33
20
110
2935
28577
1.11
2.05
4.5
4.3
14.2
14.2
pmol/l
0.11
2829
27138
3841
38102
1.32
2.01
14.9
14.8
30.0
30.0
pg
0.08
3826
37801
97
1271
0.76
1.99
1.9
2.4
0.2
0.2
e6/l
0.00
90
1205
3843
38128
1.32
1.97
15.1
14.9
132.8
133.8
g/l
6.56
3826
37826
3841
38110
1.31
1.93
15.0
14.8
4.5
4.5
e12/l
4.59
3789
37418
3840
38105
1.30
1.87
14.9
14.8
90.1
90.2
fl
1.13
3824
37806
0
53
0.00
1.86
0.0
1.1
—
—
—
0
0
90
681
1.33
1.85
3.2
4.9
1.7
1.8
%
0.15
82
641
3841
38120
1.30
1.84
15.0
14.9
6.7
6.6
e9/l
1.94
3784
37392
32
198
1.62
1.83
1.3
1.4
5.5
6.5
mmol/l
1.11
25
138
110
859
1.29
1.81
2.1
2.4
13.1
13.2
%
0.07
110
850
7
23
3.05
1.80
2.9
1.7
262.0
310.9
umol/24h
—
7
23
3836
38070
1.28
1.78
15.0
14.8
265.4
274.2
e9/l
16.08
3792
37412
575
5214
1.12
1.75
3.6
3.8
—
—
—
0
0
899
8348
1.10
1.74
2.2
2.3
20.8
27.5
ng/l
0.64
337
3259
70
516
1.36
1.72
1.5
1.5
—
—
—
0
0
5
13
3.85
1.71
1.0
1.5
—
—
—
0
0
92
1184
0.77
1.69
1.7
1.8
—
—
—
0
0
739
6808
1.11
1.68
3.1
3.0
7.7
7.6
mmol/l
0.20
660
5940
84
648
1.30
1.55
1.1
1.2
—
—
—
0
0
88
684
1.29
1.54
3.4
5.1
0.9
0.9
%
0.50
81
645
250
2165
1.17
1.54
1.6
1.8
—
—
—
0
0
748
6939
1.10
1.48
3.3
3.0
—
—
—
0
0
698
6456
1.10
1.47
3.4
3.1
1.0
1.0
kg/l
0.45
112
882
3578
35356
1.13
1.45
8.2
8.4
24.8
24.2
u/l
0.82
3511
34561
250
2179
1.16
1.43
1.6
1.7
—
—
—
0
0
248
2162
1.16
1.42
1.5
1.8
—
—
—
0
0
59
440
1.35
1.40
2.1
1.9
133.0
130.8
g/l
0.41
47
310
84
659
1.28
1.40
1.3
1.2
3.8
3.7
u/ml
0.01
42
262
393
4355
0.89
1.38
2.3
2.4
2.4
2.4
mmol/l
0.04
334
3813
444
4031
1.11
1.36
2.2
2.4
1.2
1.1
e6/l
0.27
238
2138
5
17
2.94
1.36
1.0
1.1
—
—
—
0
0
250
2189
1.15
1.36
1.6
1.8
—
—
—
0
0
171
1457
1.18
1.32
2.8
2.3
—
—
—
0
0
2444
25071
0.93
1.31
2.7
2.8
32.8
33.8
u/l
0.40
2358
24169
1357
14195
0.93
1.30
2.2
2.3
73.3
74.3
nmol/l
0.87
1290
13438
330
2955
1.13
1.29
2.3
2.6
33.8
34.8
u/ml
0.03
318
2863
220
1920
1.15
1.27
1.1
1.1
—
—
—
0
0
979
10351
0.93
1.26
1.8
1.8
98.1
100.3
pmol/l
0.89
564
5618
278
2467
1.14
1.26
1.3
1.3
28.7
38.3
au/ml
—
6
108
27
178
1.52
1.26
2.3
2.0
—
—
—
0
0
59
450
1.32
1.24
2.9
3.2
—
—
—
0
0
19
116
1.64
1.21
2.0
2.0
—
—
—
0
0
1526
14662
1.07
1.20
2.2
2.2
—
—
—
0
0
766
7181
1.08
1.20
3.1
3.4
100.8
99.8
%
0.67
740
6955
740
6932
1.08
1.18
2.0
2.0
116.9
136.0
u/l
0.79
710
6618
973
9215
1.07
1.17
1.3
1.3
1.6
1.5
u/ml
0.06
325
2732
297
2663
1.12
1.16
2.3
2.3
17.7
26.3
au/ml
0.96
19
216
2340
22806
1.06
1.15
6.2
6.7
71.9
72.4
u/l
0.26
2233
21667
3257
32103
1.08
1.15
5.1
4.9
1.6
2.2
mu/l
2.98
3142
30765
5
20
2.50
1.15
4.2
2.6
—
—
—
0
0
5
20
2.50
1.15
1.6
1.1
15.6
17.7
umol/l
—
5
20
769
7226
1.08
1.14
2.2
2.2
2.6
2.7
mg/l
0.96
670
6304
44
326
1.35
1.14
2.8
2.4
7.3
6.9
mmol/l
0.27
44
320
569
5282
1.09
1.13
1.6
1.6
—
—
—
0
0
54
413
1.31
1.13
2.1
3.0
1.8
2.4
mmol/l
0.99
28
272
5
113
0.44
1.12
1.0
1.3
—
—
—
0
0
25
167
1.50
1.12
1.4
1.7
2.6
2.0
u/field
0.23
19
91
79
638
1.24
1.09
3.6
5.2
1.1
1.2
mmol/l
1.04
70
567
5
21
2.38
1.09
4.0
2.5
—
—
—
0
0
148
1718
0.86
1.09
3.0
3.8
63.6
78.5
ng/l
2.98
138
1556
210
1852
1.14
1.08
1.0
1.1
—
—
—
0
0
21
137
1.54
1.05
2.0
2.0
—
—
—
0
0
766
7223
1.08
1.04
1.3
1.3
16.6
23.8
iu/ml
3.94
290
2295
611
5714
1.08
1.03
4.2
3.9
15.2
9.5
mg/mmol
1.82
389
3525
11
60
1.84
1.02
1.1
1.1
—
—
—
0
0
183
2080
0.87
1.02
7.9
9.8
1.0
1.1
inr
3.31
32
368
1180
11297
1.06
1.02
2.7
3.1
30.2
28.8
u/l
0.18
1126
10831
51
394
1.30
1.02
2.7
2.9
29.9
32.7
umol/l
0.46
42
352
7
35
2.00
1.00
1.3
1.1
—
—
—
0
0
9
49
1.84
0.98
1.2
1.2
—
—
—
0
0
9
157
0.57
0.98
1.8
3.1
—
—
—
0
0
35
258
1.36
0.96
1.1
1.2
—
—
—
0
0
325
2967
1.10
0.95
3.7
3.5
4.5
4.5
pmol/l
0.06
303
2669
7
37
1.89
0.94
1.3
1.5
63.4
89.4
ng/l
—
7
37
78
942
0.82
0.93
2.0
2.2
8.8
10.2
mg/l
1.23
71
884
76
625
1.22
0.92
1.1
1.0
—
—
—
0
0
59
472
1.25
0.92
2.4
2.3
—
—
—
0
0
129
1114
1.16
0.92
1.2
1.3
—
—
—
0
0
92
772
1.20
0.92
3.6
3.5
0.7
0.7
%
0.29
85
744
1544
15939
0.95
0.90
5.0
5.8
56.1
56.2
%
0.02
1466
15154
46
358
1.29
0.90
1.7
2.3
17.8
16.8
%
0.85
19
184
1657
17071
0.95
0.89
5.1
5.9
2.0
2.0
e9/l
0.54
1520
15542
119
1377
0.86
0.88
1.6
1.3
3.8
3.1
ug/l
0.78
111
1244
621
5859
1.07
0.85
1.5
1.4
—
—
—
0
0
211
1897
1.12
0.85
3.3
3.2
1.2
1.2
mmol/l
1.14
187
1684
2458
24105
1.05
0.84
3.7
3.7
9.0
9.7
mm/h
2.82
2348
22830
6
31
1.94
0.84
1.0
1.2
—
—
—
0
0
35
265
1.32
0.84
1.2
1.2
—
—
—
0
0
48
380
1.27
0.83
1.5
1.3
—
—
—
0
0
583
5493
1.07
0.83
3.3
3.2
416.4
485.7
mg/l
0.13
363
3262
504
5370
0.93
0.82
1.5
1.5
20.8
21.1
nmol/l
0.26
461
4849
147
1296
1.14
0.81
1.1
1.1
6.4
3.8
u/ml
0.43
26
244
1441
14868
0.95
0.81
5.3
6.1
0.7
0.7
%
0.02
1361
14024
86
729
1.18
0.79
1.4
1.6
—
—
—
0
0
22
156
1.41
0.78
1.4
2.6
218.7
154.7
umol/l
—
7
86
66
547
1.21
0.78
3.4
3.1
19.3
21.0
mg/l
0.19
40
333
60
493
1.22
0.77
2.2
3.0
7.4
7.4
ph
0.07
53
407
1569
16134
0.95
0.76
5.1
6.0
30.3
30.1
%
0.43
1486
15313
92
789
1.17
0.75
3.7
3.7
1.5
1.4
%
0.40
92
780
193
1741
1.11
0.75
1.4
1.3
—
—
—
0
0
131
1154
1.14
0.75
2.0
2.3
55.2
88.8
ng/l
2.11
115
1031
182
1639
1.12
0.74
1.7
1.9
—
—
—
0
0
218
1983
1.11
0.73
1.6
1.8
—
—
—
0
0
51
416
1.23
0.71
2.0
2.9
—
—
—
0
0
25
185
1.35
0.71
2.4
1.9
—
—
—
0
0
11
68
1.62
0.71
3.0
1.4
—
—
—
0
0
139
1561
0.89
0.71
1.7
1.7
—
—
—
0
0
361
3366
1.08
0.71
2.2
2.4
7.7
6.0
umol/l
0.59
308
2830
9
146
0.62
0.69
3.2
2.9
—
—
—
0
0
410
3848
1.07
0.68
1.2
1.2
139.7
154.1
iu/ml
0.37
165
1574
56
671
0.83
0.67
2.7
3.3
169.6
117.2
u/ml
0.13
45
577
47
573
0.82
0.67
8.9
3.5
1.2
1.3
mmol/l
0.82
47
562
92
1056
0.87
0.66
1.2
1.3
—
—
—
0
0
491
4642
1.07
0.66
1.3
1.3
30.1
28.9
iu/l
0.32
436
4038
7
44
1.59
0.65
1.3
1.0
—
—
—
0
0
1499
15385
0.96
0.65
5.2
6.0
2.9
2.8
%
1.13
1412
14518
22
293
0.75
0.64
1.3
1.2
—
—
—
0
0
19
137
1.39
0.64
2.5
1.9
2088.4
1961.4
ml
0.23
19
131
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
141
1568
0.90
0.63
6.7
7.8
7.0
7.1
mmol/l
0.04
136
1515
451
4263
1.07
0.62
2.1
2.3
15.1
14.6
umol/l
0.85
419
3997
37
297
1.25
0.62
1.1
1.1
17.2
7.3
iu/ml
—
7
96
1511
14731
1.04
0.62
2.0
1.9
—
—
—
0
0
8
49
1.63
0.62
1.0
1.1
—
—
—
0
0
24
182
1.32
0.61
2.3
2.1
19.9
61.5
ug/l
0.52
24
174
8
51
1.57
0.60
3.8
2.3
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
0
22
0.00
0.59
0.0
1.0
—
—
—
0
0
435
4118
1.06
0.58
1.2
1.2
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
0.5
—
0
15
7
113
0.62
0.58
2.9
1.6
—
—
—
0
0
237
2196
1.08
0.57
3.5
4.2
0.8
0.6
%
0.23
48
396
158
1438
1.10
0.57
1.2
1.2
11.1
12.4
u/l
0.65
137
1177
6
36
1.67
0.56
2.8
3.0
—
—
—
0
0
501
5260
0.95
0.56
2.4
2.4
104.9
98.2
ug/g
0.21
410
4151
16
115
1.39
0.56
1.0
1.1
—
—
—
0
0
1604
16400
0.96
0.56
5.1
6.0
0.5
0.5
e9/l
2.32
1443
14689
411
3891
1.06
0.56
3.0
3.2
0.8
0.8
mmol/l
0.31
392
3687
330
3507
0.94
0.55
1.4
1.4
—
—
—
0
0
1610
16454
0.96
0.55
5.1
6.0
0.0
0.0
e9/l
0.36
1450
14694
18
133
1.36
0.55
1.2
1.1
—
—
—
0
0
902
9324
0.96
0.54
2.9
3.2
2.3
2.3
mmol/l
2.13
828
8528
242
2598
0.93
0.54
1.8
2.4
3.9
4.0
e9/l
0.50
209
2240
140
1539
0.91
0.53
8.2
8.7
—
—
—
0
0
150
1368
1.10
0.53
1.3
1.4
30.2
27.7
u/l
0.37
130
1125
23
294
0.78
0.53
6.4
3.2
—
—
—
0
0
18
134
1.34
0.53
1.0
1.1
—
—
—
0
0
25
196
1.28
0.52
2.5
3.2
—
—
—
0
0
20
152
1.32
0.52
1.5
1.6
—
6.9
—
0
15
1140
11091
1.04
0.51
4.0
4.3
36.5
37.0
g/l
2.43
1075
10429
6
40
1.50
0.51
1.2
1.3
—
—
—
0
0
1269
12374
1.04
0.51
5.1
5.6
1.2
1.2
mmol/l
1.84
1083
10567
229
2137
1.08
0.49
1.3
1.3
242.1
234.1
miu/ml
0.13
121
1124
45
381
1.18
0.48
1.4
1.4
—
—
—
0
0
63
721
0.87
0.48
1.0
1.3
—
—
—
0
0
86
964
0.89
0.48
1.1
1.1
0.1
1.5
u/ml
5.79
15
220
13
93
1.40
0.48
1.1
1.2
—
—
—
0
0
96
1067
0.90
0.47
10.7
8.8
0.7
0.7
%
0.32
96
1061
246
2307
1.07
0.47
1.3
1.2
—
—
—
0
0
19
146
1.30
0.47
1.2
1.1
—
—
—
0
0
28
343
0.82
0.46
1.0
1.1
—
—
—
0
0
7
48
1.46
0.46
1.0
1.1
—
—
—
0
0
15
199
0.75
0.46
1.1
1.7
43.0
35.4
%
—
10
116
31
375
0.83
0.46
1.5
1.5
317.2
352.8
pmol/l
0.22
24
304
7
49
1.43
0.46
1.1
1.6
—
—
—
0
0
84
750
1.12
0.46
1.3
1.2
256.7
271.6
u/ml
0.20
59
505
8
119
0.67
0.45
1.0
1.1
—
—
—
0
0
97
1074
0.90
0.45
10.6
8.7
94.9
94.2
%
0.66
97
1069
836
8616
0.96
0.45
3.6
3.9
—
—
—
0
0
1515
15450
0.97
0.44
5.4
6.3
7.7
7.9
%
1.39
1443
14704
1678
17084
0.97
0.44
5.1
6.3
0.2
0.2
e9/l
0.38
1527
15500
18
231
0.78
0.44
2.1
3.1
871.8
889.1
e6/l
—
8
102
202
1886
1.07
0.44
3.0
3.1
—
—
—
0
0
87
781
1.12
0.44
1.1
1.1
2.7
2.4
u/ml
0.17
45
468
74
829
0.89
0.43
1.1
1.1
0.7
4.2
u/ml
2.36
30
295
3117
31411
0.96
0.43
3.1
3.1
1.2
1.2
mmol/l
2.32
3003
30198
8
57
1.40
0.42
1.4
1.2
291.8
353.9
pmol/l
—
8
38
20
158
1.27
0.41
1.2
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
2.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
12
161
0.74
0.41
1.2
1.1
—
—
—
0
0
8
59
1.36
0.41
1.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
108.4
—
0
17
42
487
0.86
0.40
1.1
1.1
—
—
—
0
0
36
422
0.85
0.40
1.7
2.0
—
—
—
0
0
12
88
1.36
0.40
1.0
1.5
—
—
—
0
0
27
325
0.83
0.40
1.3
1.2
—
—
—
0
0
7
102
0.69
0.39
1.1
1.1
—
—
—
0
0
7
104
0.67
0.39
1.1
1.1
—
—
—
0
0
7
104
0.67
0.39
1.1
1.1
—
—
—
0
0
7
104
0.67
0.39
1.1
1.1
—
—
—
0
0
21
259
0.81
0.39
1.1
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
0.0
—
0
14
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
53
601
0.88
0.38
1.2
1.3
1.1
1.4
nmol/l
1.30
45
488
242
2289
1.06
0.38
3.8
4.5
0.2
0.2
%
0.11
53
503
58
653
0.89
0.38
1.2
1.2
—
—
—
0
0
357
3415
1.05
0.38
2.1
2.4
25.9
24.1
%
1.36
315
2981
82
904
0.91
0.37
4.7
5.0
23.5
24.3
mmol/l
1.12
71
823
336
3215
1.05
0.36
1.2
1.2
—
—
—
0
0
5
76
0.66
0.35
3.0
2.8
—
—
—
0
0
5
77
0.65
0.35
1.2
1.1
—
—
—
0
0
5
77
0.65
0.35
1.2
1.1
—
—
—
0
0
5
77
0.65
0.35
1.2
1.1
—
—
—
0
0
6
42
1.43
0.35
1.2
1.2
—
—
—
0
0
64
574
1.12
0.35
1.5
1.6
0.6
0.6
g/l
0.33
53
428
396
3806
1.04
0.35
2.1
2.3
2.5
2.5
g/l
0.70
361
3563
9
126
0.71
0.35
1.2
1.2
—
—
—
0
0
9
126
0.71
0.35
2.4
2.2
—
—
—
0
0
148
1383
1.07
0.35
2.4
2.2
66.9
67.7
g/l
0.81
142
1298
1842
18673
0.97
0.35
7.1
9.1
3.9
3.9
e9/l
0.32
1653
16629
233
2212
1.06
0.34
3.8
4.5
0.0
0.2
%
0.59
49
428
2030
20057
1.02
0.33
2.6
2.6
—
—
—
0
0
6
46
1.30
0.33
1.0
1.2
—
—
—
0
0
53
593
0.89
0.33
1.1
1.1
—
—
—
0
0
43
378
1.14
0.33
1.4
1.3
3.2
3.0
g/l
0.42
32
261
60
666
0.90
0.32
1.1
1.1
0.0
0.4
u/ml
0.87
11
124
233
2449
0.95
0.32
2.9
2.6
10.2
10.5
g/l
0.72
223
2278
770
7891
0.97
0.32
1.5
1.4
2.0
2.1
g/l
1.46
504
5220
43
379
1.14
0.32
1.4
1.3
0.4
0.3
g/l
0.65
33
261
43
379
1.14
0.32
1.4
1.3
6.4
6.4
g/l
0.04
32
262
583
5662
1.03
0.32
1.4
1.4
615.0
561.5
titre
0.21
123
1180
20
241
0.83
0.31
1.8
1.4
1.0
1.1
promille
0.22
14
186
99
916
1.08
0.31
1.7
2.3
—
—
—
0
0
99
916
1.08
0.31
1.3
1.3
127.1
169.3
titre
—
7
92
7
52
1.35
0.31
2.1
7.8
—
—
—
0
0
7
52
1.35
0.31
1.4
1.3
—
—
—
0
0
94
1017
0.92
0.31
7.5
6.5
—
—
—
0
0
34
390
0.87
0.31
4.8
3.1
56.6
43.8
mg/l
0.14
25
320
3103
31219
0.97
0.31
12.1
12.4
332.2
331.6
g/l
2.42
3088
30979
250
2387
1.05
0.31
3.7
4.4
0.7
0.8
%
0.38
56
541
791
8097
0.97
0.31
5.3
6.9
—
—
—
0
0
7
53
1.32
0.30
1.0
1.3
20.0
64.3
mu/l
—
7
39
7
53
1.32
0.30
1.3
1.3
—
—
—
0
0
261
2496
1.05
0.30
1.4
1.7
287.2
336.2
mu/l
1.81
231
2223
17
138
1.23
0.30
2.3
2.4
0.5
1.2
ug/l
2.30
17
131
36
315
1.14
0.30
1.3
1.3
0.1
0.9
u/ml
0.71
14
130
371
3846
0.96
0.30
1.6
1.7
—
—
—
0
0
214
2247
0.95
0.30
2.3
2.2
0.2
0.2
g/l
0.07
206
2134
15
185
0.81
0.29
1.5
1.5
—
2356.9
—
0
28
20
239
0.84
0.29
1.5
2.7
—
—
—
0
0
109
1016
1.07
0.29
6.0
4.6
—
—
—
0
0
8
106
0.75
0.29
1.6
1.4
38.8
36.2
g/l
—
8
97
60
545
1.10
0.28
1.1
1.1
—
—
—
0
0
99
1063
0.93
0.28
10.4
8.7
1.4
1.4
%
0.13
99
1056
63
690
0.91
0.28
3.3
3.2
1.4
1.3
mg/l
0.11
58
653
85
786
1.08
0.28
1.9
2.5
—
—
—
0
0
74
680
1.09
0.28
1.3
1.2
—
—
—
0
0
117
1097
1.07
0.27
1.3
1.3
8.7
8.8
u/ml
0.01
19
189
69
751
0.92
0.27
1.6
1.3
—
—
—
0
0
25
290
0.86
0.27
1.2
1.2
—
—
—
0
0
34
385
0.88
0.27
1.2
1.2
—
—
—
0
0
22
187
1.18
0.26
1.0
1.4
—
—
—
0
0
15
182
0.82
0.26
1.5
1.7
—
—
—
0
0
22
257
0.86
0.26
4.1
2.9
4.5
3.7
nmol/l
0.17
22
248
62
676
0.92
0.26
2.2
2.6
24.6
24.5
mmol/l
0.05
56
635
105
1120
0.94
0.26
1.1
1.1
2.8
1.0
u/ml
0.72
39
418
130
1227
1.06
0.25
2.2
2.1
—
—
—
0
0
44
396
1.11
0.25
5.0
6.8
10.7
11.1
mmol/l
0.44
37
361
81
753
1.08
0.24
1.4
1.4
346.4
311.0
ug/g
0.73
42
389
44
397
1.11
0.24
5.0
6.8
105.3
105.8
mmol/l
0.26
37
362
43
388
1.11
0.24
1.4
1.4
—
—
—
0
0
66
609
1.09
0.24
2.4
2.4
—
—
—
0
0
390
3787
1.03
0.24
2.4
2.5
5.5
4.7
e6/l
0.43
187
1913
6
85
0.71
0.24
1.2
1.1
—
—
—
0
0
765
7504
1.02
0.23
1.6
1.6
1.3
1.4
mmol/l
0.68
666
6621
5
38
1.32
0.23
1.2
2.4
—
—
—
0
0
5
38
1.32
0.23
2.0
1.7
—
—
—
0
0
146
1389
1.05
0.23
1.2
1.2
—
—
—
0
0
30
338
0.89
0.23
2.4
2.7
1.2
1.3
e9/l
0.33
20
195
23
264
0.87
0.23
2.9
1.7
—
—
—
0
0
35
390
0.90
0.23
4.8
3.1
18.2
27.0
mg/l
2.52
26
320
5
39
1.28
0.23
2.6
1.9
2.2
2.6
ug/l
—
5
32
83
887
0.93
0.22
1.6
1.3
513.3
429.7
mg/l
0.80
83
849
7
92
0.76
0.22
1.3
1.4
—
—
—
0
0
156
1632
0.95
0.21
8.5
7.8
119.0
121.1
g/l
0.70
149
1575
114
1080
1.06
0.21
1.3
1.3
14.2
10.7
u/ml
0.13
15
122
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
8
104
0.77
0.21
1.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
34
306
1.11
0.21
5.6
4.8
64.5
64.3
%
0.02
34
306
20
173
1.16
0.20
1.4
1.5
134.5
135.1
nmol/l
0.02
20
173
24
272
0.88
0.20
1.1
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
102
1076
0.95
0.20
1.1
1.1
—
—
—
0
0
75
799
0.94
0.19
1.1
1.1
—
—
—
0
0
130
1241
1.05
0.19
1.1
1.2
—
—
—
0
0
23
260
0.88
0.19
1.0
1.1
281.5
304.8
mg/l
1.28
23
233
176
1693
1.04
0.19
3.7
4.1
—
7.4
—
0
7
10
122
0.82
0.19
1.4
1.6
—
111.5
—
0
17
335
3264
1.03
0.18
1.3
1.3
—
—
—
0
0
14
164
0.85
0.18
2.4
2.4
7.4
7.8
%
0.08
14
159
298
2899
1.03
0.18
1.4
1.3
172.4
185.7
u/ml
0.09
279
2700
346
3548
0.97
0.18
1.3
1.4
—
—
—
0
0
183
1897
0.96
0.18
2.0
1.8
1.3
1.3
g/l
0.16
176
1786
7
59
1.19
0.18
2.0
1.9
—
—
—
0
0
71
754
0.94
0.17
2.2
2.7
—
—
—
0
0
7
61
1.15
0.17
1.3
1.7
—
—
—
0
0
30
272
1.10
0.17
1.1
1.1
—
—
—
0
0
5
67
0.75
0.17
1.6
1.5
—
—
—
0
0
17
148
1.15
0.16
1.1
1.0
—
—
—
0
0
21
236
0.89
0.16
1.1
1.1
—
—
—
0
0
262
2550
1.03
0.16
1.3
1.2
—
—
—
0
0
337
3293
1.03
0.16
2.3
2.1
365.5
372.6
nmol/l
0.35
325
3039
73
771
0.95
0.16
1.1
1.1
0.8
3.4
u/ml
6.08
25
309
26
235
1.11
0.15
1.2
1.2
—
—
—
0
0
22
197
1.12
0.15
1.2
1.4
—
—
—
0
0
42
390
1.08
0.15
5.5
4.4
—
—
—
0
0
340
3475
0.98
0.15
1.3
1.3
—
—
—
0
0
43
401
1.07
0.14
1.4
1.6
—
—
—
0
0
104
998
1.04
0.14
1.2
1.3
20.0
38.5
u/ml
1.29
11
101
142
1372
1.04
0.14
2.2
2.6
71.5
72.6
e9/l
0.12
95
974
111
1067
1.04
0.14
2.4
2.0
—
—
—
0
0
112
1164
0.96
0.14
5.4
6.5
24.4
24.6
mmol/l
0.24
112
1158
8
99
0.81
0.13
1.0
1.1
—
—
—
0
0
48
451
1.07
0.13
1.7
2.9
23.8
24.1
mmol/l
0.29
42
395
18
201
0.90
0.13
1.1
1.1
1486.4
1515.4
miu/ml
0.03
18
201
34
315
1.08
0.13
1.4
1.5
0.9
1.0
g/l
0.99
34
315
13
113
1.15
0.13
1.2
1.2
5.4
5.0
nmol/l
0.18
13
105
193
1982
0.97
0.13
7.5
7.0
0.5
0.7
mmol/l
0.26
148
1511
9
106
0.85
0.13
1.8
1.4
21.9
33.7
mmol/l
—
9
93
131
1352
0.97
0.12
1.9
1.4
0.5
0.5
nmol/l
0.01
106
1060
3315
33072
1.01
0.12
10.2
10.8
39.6
39.8
%
1.03
2747
28130
33
354
0.93
0.12
1.4
1.4
—
—
—
0
0
26
282
0.92
0.12
2.1
2.2
76.2
75.0
%
0.26
26
276
97
1005
0.96
0.11
1.1
1.1
2.8
5.0
u/ml
1.75
49
518
282
2767
1.02
0.11
2.3
2.4
37.7
36.6
u/l
0.04
250
2369
46
436
1.06
0.10
1.3
1.3
—
—
—
0
0
46
484
0.95
0.10
4.2
4.6
65.5
100.6
u/ml
0.27
14
161
24
259
0.93
0.10
1.2
1.5
—
—
—
0
0
24
259
0.93
0.10
1.2
1.5
—
—
—
0
0
24
259
0.93
0.10
1.2
1.5
—
—
—
0
0
24
259
0.93
0.10
1.2
1.5
—
—
—
0
0
17
154
1.10
0.10
2.3
2.1
26.2
30.2
umol/l
2.13
17
146
41
388
1.06
0.10
1.8
1.6
—
—
—
0
0
5
47
1.06
0.09
1.0
1.1
—
—
—
0
0
10
87
1.15
0.09
2.4
2.0
—
—
—
0
0
23
213
1.08
0.09
3.7
2.5
—
—
—
0
0
202
2060
0.98
0.09
1.9
2.5
1.7
1.7
%
0.07
179
1832
193
1969
0.98
0.09
7.5
6.9
5.0
5.1
kpa
0.03
183
1895
17
186
0.91
0.09
1.4
1.6
9394.8
20160.3
e6/l
0.43
11
135
92
949
0.97
0.09
1.2
1.1
—
—
—
0
0
92
949
0.97
0.09
1.2
1.1
—
—
—
0
0
3298
32919
1.01
0.09
3.5
3.7
3.0
3.0
mmol/l
0.61
3147
31528
193
1968
0.98
0.09
7.4
6.9
14.1
14.0
kpa
0.11
184
1891
92
948
0.97
0.08
8.2
9.1
—
—
—
0
0
22
204
1.08
0.08
1.1
1.1
8.1
9.3
u/ml
—
5
32
554
5485
1.01
0.08
1.6
1.5
421.9
36116652.6
pmol/l
4.95
498
4887
1104
10971
1.01
0.08
4.5
5.0
1.2
1.2
mmol/l
0.80
1025
10118
5
60
0.83
0.08
1.0
1.5
20.8
45.1
%
—
5
51
18
195
0.92
0.08
1.7
1.5
—
—
—
0
0
11
98
1.12
0.07
1.3
1.3
—
—
—
0
0
6
72
0.83
0.07
1.3
1.8
—
—
—
0
0
157
1601
0.98
0.07
1.4
1.3
—
—
—
0
0
26
276
0.94
0.07
2.1
2.2
16.4
13.6
%
0.60
13
151
17
157
1.08
0.07
3.5
2.5
11.0
10.8
%
0.04
17
157
636
6312
1.01
0.07
2.5
2.5
—
—
—
0
0
239
2423
0.99
0.06
1.4
1.3
—
—
—
0
0
9
100
0.90
0.06
5.3
4.8
—
—
—
0
0
352
3484
1.01
0.06
1.4
1.5
—
—
—
0
0
3081
30761
1.01
0.06
3.3
3.4
5.5
5.6
mmol/l
1.36
2943
29247
3264
32685
0.99
0.06
3.4
3.5
4.9
4.9
mmol/l
3.70
3148
31516
591
5953
0.99
0.06
1.3
1.3
—
—
—
0
0
432
4358
0.99
0.06
1.2
1.2
—
—
—
0
0
2788
27829
1.01
0.06
3.9
4.0
37.2
37.4
mmol/mol
0.80
2664
26650
12
131
0.92
0.05
1.4
2.3
237.1
152.4
e6/l
—
7
72
12
131
0.92
0.05
1.1
1.1
—
—
—
0
0
198
1954
1.01
0.05
1.4
1.4
—
—
—
0
0
14
151
0.93
0.05
1.0
1.1
0.5
1.5
u/ml
—
6
82
37
384
0.96
0.05
1.1
1.0
—
—
—
0
0
103
1049
0.98
0.05
1.2
1.2
—
—
—
0
0
157
1592
0.99
0.05
1.4
1.3
—
—
—
0
0
40
414
0.97
0.05
2.2
1.3
—
—
—
0
0
1014
10177
1.00
0.04
5.4
6.2
—
—
—
0
0
170
1680
1.01
0.04
7.8
7.5
97.1
96.3
%
1.91
163
1617
109
1107
0.98
0.04
2.0
2.7
5.0
5.1
kpa
0.64
96
1041
93
946
0.98
0.04
1.1
1.1
0.7
1.0
u/ml
0.28
35
386
36
372
0.97
0.04
2.5
2.6
19.2
88.3
ug/min
2.97
23
243
17
180
0.94
0.04
1.2
1.1
—
—
—
0
0
12
129
0.93
0.03
2.0
2.0
—
—
—
0
0
14
131
1.07
0.03
1.0
1.2
—
—
—
0
0
216
2179
0.99
0.03
2.9
3.3
—
—
—
0
0
24
230
1.04
0.03
1.9
2.3
—
—
—
0
0
15
141
1.06
0.03
1.1
1.1
—
—
—
0
0
3253
32557
1.00
0.03
3.4
3.4
1.5
1.6
mmol/l
4.24
3126
31341
72
707
1.02
0.03
3.5
3.6
58.5
56.6
%
0.88
72
707
211
2095
1.01
0.02
3.2
3.5
22.8
28.0
ug/l
0.09
147
1475
104
1028
1.01
0.02
8.6
6.4
24.3
24.3
mmol/l
0.04
94
959
34
331
1.03
0.02
1.1
1.2
—
—
—
0
0
741
7430
1.00
0.02
3.1
3.8
7.4
7.4
ph
0.06
156
1381
18
188
0.96
0.02
1.1
1.1
—
—
—
0
0
47
479
0.98
0.02
1.1
1.1
60.3
769.4
iu/ml
0.56
18
116
10
107
0.93
0.02
2.8
2.9
—
—
—
0
0
11
117
0.94
0.01
1.4
1.1
—
3.2
iu/ml
—
0
9
24
247
0.97
0.01
1.5
1.7
39.0
52.9
%
0.90
16
155
27
263
1.03
0.01
6.1
7.4
—
—
—
0
0
153
1539
0.99
0.01
1.8
1.7
—
—
—
0
0
282
2830
1.00
0.01
4.1
5.5
1.0
1.0
mmol/l
0.33
272
2680
108
1088
0.99
0.01
2.0
2.7
7.4
7.4
ph
1.23
16
135
52
527
0.99
0.01
1.6
1.7
10161.0
7557.6
e6/l
0.15
42
386
115
1157
0.99
0.00
1.9
1.9
5.9
6.2
ug/l
0.07
108
1009
175
1757
1.00
0.00
1.2
1.3
2.2
1.0
u/ml
0.33
13
151
65
656
0.99
0.00
7.2
4.2
—
—
—
0
0
11
108
1.02
0.00
1.0
1.2
—
—
—
0
0
13
128
1.02
0.00
2.3
2.2
—
—
—
0
0
24
239
1.00
0.00
1.3
1.8
—
—
—
0
0
25
249
1.00
0.00
1.3
1.3
—
63.9
—
0
19
33
331
1.00
0.00
1.1
1.0
—
—
—
0
0
30
304
0.99
0.00
1.6
2.5
—
—
—
0
0
26
264
0.98
0.00
1.5
1.3
—
—
—
0
0
35
354
0.99
0.00
1.1
1.0
1.7
0.5
u/ml
0.43
11
78
21
206
1.02
0.00
1.3
3.0
—
—
—
0
0
17
174
0.98
0.00
1.1
1.1
—
—
—
0
0
36
356
1.01
0.00
1.1
1.0
0.4
0.4
u/ml
—
9
96
163
1631
1.00
0.00
3.8
4.2
1.4
1.8
mmol/l
0.90
133
1329
78
783
1.00
0.00
1.7
1.3
83.7
30.9
e6/l
0.33
60
605
72
717
1.00
0.00
1.4
1.5
—
6.9
—
0
15
78
783
1.00
0.00
1.7
1.4
216.1
5407.0
e6/l
0.57
61
633
15
147
1.02
0.00
1.0
2.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
0.00
1.0
1.1
—
—
—
0
0
9
97
0.93
0.00
1.6
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
0.6
—
0
5
0
9
0.00
0.00
0.0
3.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
56
0.89
0.00
2.6
1.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
131.7
—
0
5
7
77
0.91
0.00
1.0
1.1
—
—
—
0
0
8
81
0.99
0.00
1.6
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
28.3
—
0
5
366
3660
1.00
0.00
1.9
1.7
1210.9
1193.6
nmol/l
0.15
304
2907
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
8
84
0.95
0.00
1.5
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
7
78
0.90
0.00
1.7
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
65
0.92
0.00
3.0
2.4
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint O15_TWIN_GEST and mortality.

Females

Parameter HR [95% CI] p-value
O15_TWIN_GEST 0.483 [0.39, 0.6] < 0.001
Birth year 0.998 [0.99, 1.01] 0.62

During the follow-up period (1.1.1998 — 31.12.2019), 99 out of 18735 females with O15_TWIN_GEST died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_TWIN_GEST.

N-year risk Females Males
1 0.054% No data
5 0.288% No data
10 0.77% No data
15 1.528% No data
20 2.695% No data

Relationships between endpoints

↥

Index endpoint: O15_TWIN_GEST – Twin gestation

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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