Multiple gestation

O15_MULTIP_GEST

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O30
  • Hospital discharge: ICD-9 651
  • Hospital discharge: ICD-8 Y8[0-7]
  • Cause of death: ICD-10 O30
  • Cause of death: ICD-9 651
  • Cause of death: ICD-8 Y8[0-7]

2 out of 7 registries used, show all original rules.

4073

4. Check minimum number of events

None

4073

5. Include endpoints

4073

6. Filter based on genotype QC (FinnGen only)

4073

Control definitions (FinnGen only)

Control exclude
O15_MATERN_CARE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF6v3
Parent code in ICD-10
O30-O48
Name in latin
Plurifetatio

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 28565 28565 -
Only index persons 28227 28227 -
Unadjusted period prevalence (%)
Whole population 0.82 0.82 -
Only index persons 1.04 1.04 -
Median age at first event (years)
Whole population - 30.85 -
Only index persons - 30.84 -

-FinnGen-

Key figures

All Female Male
Number of individuals 4073 4073 -
Unadjusted period prevalence (%) 1.39 1.39 -
Median age at first event (years) 31.09 31.09 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3683
Matched controls
36829
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
2795.1
323.0
508
*
O60
ICD-10 Finland
Preterm labour and delivery
30.0
323.0
543
211
Z37.2
ICD-10 Finland
Twins, both liveborn
879.8
323.0
322
*
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
638.0
323.0
681
13
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
5.1
323.0
1321
3640
6510A
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, RASKAUDEN AIKANA]
+∞
323.0
454
*
O30.0
ICD-10 Finland
Twin pregnancy
4503599627370496.0
323.0
2267
*
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
9.2
323.0
940
1322
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
28.8
323.0
1117
547
6510B
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, SYNNYTYKSEN AIKANA]
+∞
323.0
681
*
O84.2
ICD-10 Finland
Multiple delivery, all by caesarean section
810.1
323.0
493
7
O30.00
ICD-10 Finland
Twin pregnancy with separate amniotic and chorionic sacs
+∞
323.0
488
*
O32.1
ICD-10 Finland
Maternal care for breech presentation
581.9
323.0
461
9
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
17.9
323.0
1434
1265
O84.8
ICD-10 Finland
Other multiple delivery
811.2
307.9
299
*
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
3057.7
307.4
293
*
O82.0
ICD-10 Finland
Delivery by elective caesarean section
18.2
280.1
449
279
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
+∞
268.0
254
*
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
3.2
223.7
1718
7909
W84
ICPC
Pregnancy high risk
10.3
223.2
463
505
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
3.5
209.4
1228
4569
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
8.0
200.4
486
687
Z39.2
ICD-10 Finland
Routine postpartum follow-up
3.7
189.3
1004
3399
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
4.7
184.3
710
1787
O30.01
ICD-10 Finland
Twin pregnancy with a shared chorionic sac and a separate amniotic sac
+∞
174.3
166
*
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
337.6
162.3
163
5
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
7.8
158.5
388
549
G03GA01
ATC
chorionic gonadotrophin; parenteral
4.8
149.8
553
1311
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
+∞
144.7
138
*
G03DA04
ATC
progesterone; systemic, rectal, vaginal
5.6
144.7
454
895
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
1435.0
141.6
137
*
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
+∞
138.4
132
*
O64.1
ICD-10 Finland
Obstructed labour due to breech presentation
27.0
135.9
190
74
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
4.1
130.3
572
1592
O47.1
ICD-10 Finland
False labour at or after 37 completed weeks of gestation
116.7
124.9
135
12
SPAT1379
SPAT
Health check-up of pregnant person
3.3
124.3
727
2552
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
3.6
124.2
639
2031
XMA22
NOMESCO Finland
General examination of pregnant woman
4.2
120.6
507
1350
8811
FHL
Cesarean section
4.2
114.5
483
1286
G03GA06
ATC
follitropin beta; parenteral
5.3
114.1
372
759
O34.3
ICD-10 Finland
Maternal care for cervical incompetence
+∞
109.9
105
*
MAG00
NOMESCO Finland
Assisted breech delivery
47.9
109.6
134
29
SPAT1197
SPAT
Extensive health check-up of expecting family
2.8
107.3
802
3289
SPAT1380
SPAT
Postpartum check-up
3.2
100.8
597
2085
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
501.0
98.9
98
*
O68.0
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly
4.2
97.3
406
1063
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
2.8
95.5
735
3046
O48
ICD-10 Finland
Prolonged pregnancy
+∞
95.2
91
*
6440B
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS]
9.7
94.5
199
216
Z32.1
ICD-10 Finland
Pregnancy confirmed
2.9
92.2
660
2608
O41.0
ICD-10 Finland
Oligohydramnios
317.1
91.2
92
*
W78
ICPC
Pregnancy
2.5
90.5
867
4056
H01CA02
ATC
nafarelin; nasal
4.3
88.0
349
868
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
442.9
87.5
87
*
G03GA02
ATC
human menopausal gonadotrophin; parenteral
4.5
86.3
329
786
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
3.8
82.6
382
1090
O42.1
ICD-10 Finland
Premature rupture of membranes, onset of labour after 24 hours
+∞
78.4
75
*
O30.1
ICD-10 Finland
Triplet pregnancy
+∞
76.3
73
*
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
9.4
75.3
161
179
O20.0
ICD-10 Finland
Threatened abortion
5.2
74.7
245
498
WX320
NOMESCO Finland
Spinalanesthesy
2.5
74.3
706
3245
O40
ICD-10 Finland
Polyhydramnios
732.5
73.4
72
*
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
6.0
69.5
201
351
MAA00
NOMESCO Finland
Amniocentesis
8.0
68.0
160
209
WX306
NOMESCO Finland
Lumbar epidural anesthesy
3.0
66.9
425
1532
SPAT1196
SPAT
Monitoring of normal pregnancy
3.0
66.8
426
1539
O35.9
ICD-10 Finland
Maternal care for (suspected) fetal abnormality and damage, unspecified
659.7
66.1
65
*
N97.9
ICD-10 Finland
Female infertility, unspecified
2.7
64.8
504
2061
O47.9
ICD-10 Finland
False labour, unspecified
15.8
64.0
106
69
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
2.5
63.5
552
2403
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
6.1
63.1
180
309
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
4.6
61.2
223
506
L02AE01
ATC
buserelin; implant, nasal, parenteral
5.6
59.5
180
332
G03GA05
ATC
follitropin alfa; parenteral
3.5
58.4
292
881
W92
ICPC
Compl labour/ delivery livebirth
7.1
58.3
147
213
6440A
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS IMMINENS]
4.9
58.1
198
419
O80.1
ICD-10 Finland
Spontaneous breech delivery
20.2
57.6
87
44
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
4.3
57.3
227
559
O36.4
ICD-10 Finland
Maternal care for intrauterine death
+∞
55.3
53
*
6522B
ICD-9 Finland
Malposition and malpresentation of foetus, Breech presentation without mention of version[PRAESENTATIO CLUNIUM,SYNNYTYKSEN AIKANA]
5.4
55.3
173
332
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
3.1
54.2
315
1062
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.6
53.1
437
1832
O41.1
ICD-10 Finland
Infection of amniotic sac and membranes
+∞
52.2
50
*
G03GB02
ATC
clomifene; oral
3.7
51.8
240
679
O82.11
ICD-10 Finland
Childbirth with an emergency caesarean section in an emergency
11.0
51.6
100
93
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
2.3
51.3
523
2450
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
5.8
50.5
149
267
O30.9
ICD-10 Finland
Multiple gestation, unspecified
+∞
50.1
48
*
N97.0
ICD-10 Finland
Female infertility associated with anovulation
3.9
49.3
214
573
O44.0
ICD-10 Finland
Placenta praevia specified as without haemorrhage
+∞
48.0
46
*
O83.0
ICD-10 Finland
Breech extraction
124.1
45.8
49
*
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
5.8
44.4
129
227
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
6.2
44.2
123
205
O44.1
ICD-10 Finland
Placenta praevia with haemorrhage
+∞
43.8
42
*
SPAT1357
SPAT
Monitoring of problem during pregnancy
4.3
42.9
168
409
O02.1
ICD-10 Finland
Missed abortion
2.5
42.7
363
1541
NE1AG
NOMESCO Finland
MRI pelvimetry with high intensity magnet
148.4
41.8
44
*
O32.2
ICD-10 Finland
Maternal care for transverse and oblique lie
91.1
40.8
45
5
O84.1
ICD-10 Finland
Multiple delivery, all by forceps and vacuum extractor
145.0
40.8
43
*
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
10.3
39.7
79
78
W85
ICPC
Gestational diabetes
3.1
39.0
225
752
6441A
ICD-9 Finland
Early or threatened labour, Other threatened labour
+∞
38.6
37
*
6581A
ICD-9 Finland
Other problems associated with amniotic cavity and membranes, Premature rupture of membranes
+∞
38.6
37
*
O43.0
ICD-10 Finland
Placental transfusion syndromes
+∞
37.6
36
*
O14.1
ICD-10 Finland
Severe pre-eclampsia
7.1
37.4
93
133
O36.9
ICD-10 Finland
Maternal care for fetal problem, unspecified
371.0
37.1
37
*
MAC96
NOMESCO Finland
Other induction or advancement of labour
3.9
36.6
159
426
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
3.2
36.4
204
668
Z39.1
ICD-10 Finland
Care and examination of lactating mother
4.3
36.2
140
337
H01CC01
ATC
ganirelix; parenteral
3.1
36.0
211
712
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.6
35.4
1564
11811
WX307
NOMESCO Finland
Obstetric epidural analgesia
2.1
35.4
429
2154
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
5.6
35.3
106
195
O99.80
ICD-10 Finland
The fear of childbirth
2.7
34.9
247
942
MAB20
NOMESCO Finland
Failed external version
124.5
34.7
37
*
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
6.0
34.6
97
164
O31.2
ICD-10 Finland
Continuing pregnancy after intrauterine death of one fetus or more
+∞
34.4
33
*
O31.8
ICD-10 Finland
Other complications specific to multiple gestation
+∞
34.4
33
*
SPAT1189
SPAT
Other ultrasound examination during pregnancy
3.4
33.1
165
495
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
2.9
33.1
207
730
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
1.8
33.0
696
4280
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
4.7
32.8
115
252
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
1.9
32.1
551
3162
O69.0
ICD-10 Finland
Labour and delivery complicated by prolapse of cord
36.7
31.5
40
11
6582B
ICD-9 Finland
Other problems associated with amniotic cavity and membranes, Delayed delivery after spontaneous or unspecified rupture of membranes
+∞
31.3
30
*
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
4.4
31.2
117
274
O80.8
ICD-10 Finland
Other single spontaneous delivery
3.1
31.1
181
609
O32.0
ICD-10 Finland
Maternal care for unstable lie
315.4
30.9
31
*
O63.0
ICD-10 Finland
Prolonged first stage (of labour)
4.5
30.5
111
253
MA4AT
NOMESCO Finland
Chorion biopsy with ultrasound guidance
45.4
29.6
36
8
G03GA04
ATC
urofollitropin; parenteral
5.3
29.3
91
175
6526B
ICD-9 Finland
Malposition and malpresentation of foetus, Multiple gestation with malpresentation of one foetus or more[MONISIKIÖN YHT ESIINT VIRHETARJ,SYNNYTYKSEN AIKANA]
104.2
28.7
31
*
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
3.3
28.6
148
458
W90
ICPC
Uncompl labour/delivery livebirth
2.6
28.5
219
876
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
2.7
28.4
205
791
O45.9
ICD-10 Finland
Premature separation of placenta, unspecified
+∞
28.2
27
*
6511B
ICD-9 Finland
Multiple gestation, Triplet pregnancy[TRIGEMINI,SYNNYTYKSEN AIKANA]
+∞
28.2
27
*
MAE00
NOMESCO Finland
Outlet vacuum delivery
2.2
28.0
315
1523
O72.0
ICD-10 Finland
Third-stage haemorrhage
3.4
27.8
141
430
MAX99
NOMESCO Finland
Assistance to normal delivery
1.8
27.6
497
2887
O61.0
ICD-10 Finland
Failed medical induction of labour
6.6
27.2
71
110
O36.3
ICD-10 Finland
Maternal care for signs of fetal hypoxia
+∞
27.1
26
*
O34.1
ICD-10 Finland
Maternal care for tumour of corpus uteri
+∞
27.1
26
*
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
3.9
26.8
114
301
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
8.9
26.7
57
65
LGA20
NOMESCO Finland
Sterilisation by constriction of Fallopian tubes
5.7
26.5
77
137
G02CB01
ATC
bromocriptine; systemic
3.3
26.4
139
436
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
4.2
26.3
101
243
O46.8
ICD-10 Finland
Other antepartum haemorrhage
262.4
25.7
26
*
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
6.2
25.7
70
115
N97.4
ICD-10 Finland
Female infertility associated with male factors
3.0
25.3
153
529
LCA30
NOMESCO Finland
Transfer of oocyte or embryo to uterus in assisted fertilisation
6.4
25.3
67
106
O28.3
ICD-10 Finland
Abnormal ultrasonic finding on antenatal screening of mother
9.7
25.2
51
53
O42.2
ICD-10 Finland
Premature rupture of membranes, labour delayed by therapy
+∞
25.0
24
*
FM1NE
NOMESCO Finland
Ultrasound examination of fetal heart
58.4
25.0
29
5
FM1QE
NOMESCO Finland
Extensive ultrasound of fetal heart
11.1
24.8
47
43
TLW10
NOMESCO Finland
Transfer of fresh embryo
3.2
24.5
132
422
O81.4
ICD-10 Finland
Vacuum extractor delivery
2.0
24.0
333
1758
O32.5
ICD-10 Finland
Maternal care for multiple gestation with malpresentation of one fetus or more
+∞
24.0
23
*
MAG10
NOMESCO Finland
Breech extraction delivery
+∞
24.0
23
*
B01AB05
ATC
enoxaparin; parenteral
1.6
23.9
771
5281
L02AE02
ATC
leuprorelin; implant, parenteral
3.1
23.8
133
437
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.1
23.7
300
1524
TLW00
NOMESCO Finland
Insemination
2.9
23.6
146
511
O86.0
ICD-10 Finland
Infection of obstetric surgical wound
6.1
23.2
64
107
O21.0
ICD-10 Finland
Mild hyperemesis gravidarum
5.1
23.0
73
145
LGA10
NOMESCO Finland
Sterilisation by destruction or division of Fallopian tubes
5.8
22.6
64
111
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
3.7
22.5
100
275
Z30.2
ICD-10 Finland
Sterilization
1.7
22.2
550
3507
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
2.2
22.2
244
1168
O36.0
ICD-10 Finland
Maternal care for rhesus isoimmunization
+∞
21.9
21
*
6511A
ICD-9 Finland
Multiple gestation, Triplet pregnancy[TRIGEMINI,RASKAUDEN AIKANA]
+∞
21.9
21
*
A05AA02
ATC
ursodeoxycholic acid; oral
3.8
21.9
94
252
6289A
ICD-9 Finland
Infertility, female, Of unspecified origin[STERILITAS ET INFERTILITAS MULIERIS NUD PRIM]
4.7
21.8
75
163
O64.8
ICD-10 Finland
Obstructed labour due to other malposition and malpresentation
7.2
21.5
52
73
8803
FHL
Stern exit
7.3
20.9
50
69
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
4.3
20.8
77
180
6282B
ICD-9 Finland
Infertility, female, Of tubal origin[STERIL ET INFERT EX ORIG TUBAE UTERINAE SEC]
9.2
20.8
43
47
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
2.7
20.5
140
525
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
3.2
20.5
108
341
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
2.5
20.4
166
685
MWE00
NOMESCO Finland
Reoperation for deep haemorrhage in obstetric surgery
27.2
20.0
27
10
W29
ICPC
Pregnancy symptom/complaint other
3.0
19.9
120
414
6467A
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Liver disorders in pregnancy[HEPATOSIS GRAVIDARUM]
5.3
19.9
61
117
N98.1
ICD-10 Finland
Hyperstimulation of ovaries
5.5
19.9
59
109
SPAT1200
SPAT
Guidance for breast-feeding and breast care
2.9
19.9
122
428
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
3.9
19.8
82
213
O30.02
ICD-10 Finland
Twin pregnancy with a shared amniotic and chorionic sac
+∞
19.8
19
*
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
2.7
19.8
141
541
Z36.8
ICD-10 Finland
Other antenatal screening
3.0
19.6
115
392
O26.7
ICD-10 Finland
Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
5.1
19.4
61
121
G03DB01
ATC
dydrogesterone; oral
1.5
18.9
740
5264
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
4.8
18.8
63
134
TLW12
NOMESCO Finland
Insertion of frozen embryo
3.0
18.6
107
359
6400A
ICD-9 Finland
Haemorrhage in early pregnancy, Threatened abortion
3.9
18.4
75
193
QBJ30
NOMESCO Finland
Correction of abdominal apron
4.1
18.2
71
176
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.8
18.1
121
449
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
2.8
18.0
120
445
SPAT1246
SPAT
Screening of depression or other psychiatric problem
2.2
17.9
196
938
J01DA01
ATC
[U] cefalexin; systemic
1.4
17.8
2198
19187
Z31.2
ICD-10 Finland
In vitrofertilization
4.1
17.8
69
170
O83.1
ICD-10 Finland
Other assisted breech delivery
66.9
17.7
20
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
17.2
941
7149
LAA06
NOMESCO Finland
Transvaginal puncture of ovarian cyst
4.2
16.8
63
151
O34.0
ICD-10 Finland
Maternal care for congenital malformation of uterus
+∞
16.7
16
*
O31.1
ICD-10 Finland
Continuing pregnancy after abortion of one fetus or more
+∞
16.7
16
*
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
3.1
16.5
90
293
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.6
16.4
534
3629
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
2.2
15.9
172
819
Z35.1
ICD-10 Finland
Supervision of pregnancy with history of abortive outcome
6.6
15.8
40
61
C08CA05
ATC
nifedipine; systemic
2.4
15.7
139
601
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
2.1
15.7
179
870
MAB00
NOMESCO Finland
Cerclage of cervix of pregnant uterus
85.4
15.6
17
*
8216
FHL
Applicatio ovii
19.3
15.5
23
12
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.5
15.4
585
4116
O10.0
ICD-10 Finland
Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
2.8
15.2
95
339
SPAT1190
SPAT
Insertion or removal of intrauterine contraceptive device
1.7
15.0
329
2016
N02BE01
ATC
paracetamol; systemic, rectal
1.4
14.7
2892
26711
SPAT1391
SPAT
Counselling and guidance related to family situation
3.8
14.7
62
166
O20.8
ICD-10 Finland
Other haemorrhage in early pregnancy
6.1
14.7
39
64
O35.0
ICD-10 Finland
Maternal care for (suspected) central nervous system malformation in fetus
+∞
14.6
14
*
6570A
ICD-9 Finland
Polyhydramnios[POLYHYDRAMNION, RASKAUDEN AIKANA]
+∞
14.6
14
*
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
14.3
1218
9913
O47
ICD-10 Finland
False labour
5.6
14.3
41
74
1413
FHL
Laparoscopy and other therapeutic procedure
2.5
14.3
112
457
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.3
14.3
1221
9944
P01AB01
ATC
metronidazole; oral, rectal
1.3
14.1
1436
11996
O21
ICD-10 Finland
Excessive vomiting in pregnancy
5.0
13.9
44
89
O64.4
ICD-10 Finland
Obstructed labour due to shoulder presentation
53.5
13.8
16
*
O30.8
ICD-10 Finland
Other multiple gestation
+∞
13.5
13
*
O30.2
ICD-10 Finland
Quadruplet pregnancy
+∞
13.5
13
*
SPAT1263
SPAT
Sampling
1.3
13.5
1276
10525
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
13.2
260
1544
SPAT1373
SPAT
Combined screening in early pregnancy
3.2
13.2
67
209
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
4.3
13.1
48
114
Z36.4
ICD-10 Finland
Antenatal screening for fetal growth retardation using ultrasound and other physical methods
2.8
13.0
85
313
XLA10
NOMESCO Finland
NA
1.8
12.8
230
1329
O99.5
ICD-10 Finland
Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
4.2
12.8
47
112
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
3.7
12.7
54
147
J01DB01
ATC
cefalexin; oral
1.3
12.6
2820
26123
Z31.5
ICD-10 Finland
Genetic counselling
1.8
12.6
210
1185
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
4.2
12.5
47
114
O43.8
ICD-10 Finland
Other placental disorders
+∞
12.5
12
*
O30
ICD-10 Finland
Multiple gestation
+∞
12.5
12
*
6419A
ICD-9 Finland
Antepartum haemorrhage, abruptio placentae and placenta praevia, Unspecified antepartum haemorrhage[HAEMORRHAGIA NUD IN GRAVIDITATE,HOITOJ ENN SYNN NUD]
+∞
12.5
12
*
O35.5
ICD-10 Finland
Maternal care for (suspected) damage to fetus by drugs
+∞
12.5
12
*
6412B
ICD-9 Finland
Antepartum haemorrhage, abruptio placentae and placenta praevia, Premature separation of placenta[ABLATIO PLACENTAE ANTETEMPUS,SYNN PÄÄTT HOITOJAKSO]
+∞
12.5
12
*
WX290
NOMESCO Finland
Other blockade of nerve
1.3
12.4
1741
15115
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
2.1
12.4
139
672
ULC02
NOMESCO Finland
Hysteroscopy
1.8
12.4
219
1259
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
0.5
12.2
85
1727
N97.1
ICD-10 Finland
Female infertility of tubal origin
2.8
12.1
78
286
W05
ICPC
Pregnancy vomiting/nausea
4.3
11.9
43
101
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
11.9
2594
23801
O12.1
ICD-10 Finland
Gestational proteinuria
4.3
11.8
43
102
WX810
NOMESCO Finland
Neonatal intesive care
11.7
11.8
21
18
N97.8
ICD-10 Finland
Female infertility of other origin
2.2
11.8
123
579
LBF01
NOMESCO Finland
Laparoscopic perfusion of Fallopian tube
2.4
11.7
101
436
SPAT1316
SPAT
Extensive health check-up of children and adolescents
2.1
11.6
129
625
O33.5
ICD-10 Finland
Maternal care for disproportion due to unusually large fetus
+∞
11.5
11
*
O33.9
ICD-10 Finland
Maternal care for disproportion, unspecified
+∞
11.5
11
*
6418A
ICD-9 Finland
Antepartum haemorrhage, abruptio placentae and placenta praevia, Other antepartum haemorrhage[ALIA HAEMORRHAGIA IN GRAVIDITATE,HOITOJ ENNEN SYNN]
+∞
11.5
11
*
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
2.2
11.4
113
519
MAB10
NOMESCO Finland
External version
13.6
11.4
19
14
8219
FHL
Other measure in this category
8.9
11.2
23
26
J01CA08
ATC
pivmecillinam; oral
1.3
11.1
1691
14756
O62.2
ICD-10 Finland
Other uterine inertia
6.1
11.0
29
48
M62.0
ICD-10 Finland
Diastasis of muscle
9.2
11.0
22
24
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
1.4
10.9
476
3433
SPAT1375
SPAT
Structural ultrasound screening, weeks 18+0-21+6
3.9
10.8
43
111
6282A
ICD-9 Finland
Infertility, female, Of tubal origin[STERIL ET INFERT EX ORIG TUBAE UTERINAE PRIM]
6.9
10.8
26
38
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
10.8
857
6849
O12.0
ICD-10 Finland
Gestational oedema
5.0
10.7
33
66
1410
FHL
Laparoscopy
2.1
10.6
117
568
SPAT1187
SPAT
General ultrasound examination in early pregnancy
3.7
10.5
45
124
Z29
ICPC
Social problem NOS
2.8
10.5
66
239
MBA04
NOMESCO Finland
Curettage of uterus after delivery
4.6
10.4
35
77
O35.2
ICD-10 Finland
Maternal care for (suspected) hereditary disease in fetus
+∞
10.4
10
*
O33.3
ICD-10 Finland
Maternal care for disproportion due to outlet contraction of pelvis
+∞
10.4
10
*
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
10.3
1705
14978
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.6
10.1
273
1769
MA3AE
NOMESCO Finland
Combined first trimester screening
1.9
10.1
155
851
MBC10
NOMESCO Finland
Repair of obstetric laceration of vagina
2.5
10.0
78
320
O85
ICD-10 Finland
Puerperal sepsis
3.3
9.9
49
152
6522A
ICD-9 Finland
Malposition and malpresentation of foetus, Breech presentation without mention of version[PRAESENTATIO CLUNIUM,RASKAUDEN AIKANA]
4.1
9.8
37
92
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
3.6
9.8
42
117
WYA40
NOMESCO Finland
Assessment of oral health and treatment needs for family expecting first child
2.5
9.7
74
301
A02BC01
ATC
omeprazole; systemic
1.3
9.6
666
5205
O73.0
ICD-10 Finland
Retained placenta without haemorrhage
3.2
9.5
47
147
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
2.2
9.4
94
435
JAF10
NOMESCO Finland
Repair of umbilical hernia
2.9
9.4
55
191
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.5
9.4
339
2351
O84.9
ICD-10 Finland
Multiple delivery, unspecified
100.3
9.4
10
*
MAE03
NOMESCO Finland
Mid-cavity or high vacuum delivery
4.9
9.4
29
59
O63.2
ICD-10 Finland
Delayed delivery of second twin, triplet, etc.
+∞
9.4
9
*
O41.8
ICD-10 Finland
Other specified disorders of amniotic fluid and membranes
+∞
9.4
9
*
O33.1
ICD-10 Finland
Maternal care for disproportion due to generally contracted pelvis
+∞
9.4
9
*
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
1.3
9.3
641
5000
SPAT1303
SPAT
Counselling and guidance related to growth and development
3.4
9.2
42
123
Z31.1
ICD-10 Finland
Artificial insemination
3.9
9.2
36
93
O62.0
ICD-10 Finland
Primary inadequate contractions
5.4
9.2
26
48
6523B
ICD-9 Finland
Malposition and malpresentation of foetus, Transverse or oblique presentation[SITUS TRANSVERSUS ET OBLIQUUS,SYNNYTYKSEN AIKANA]
13.7
9.2
15
11
MBA05
NOMESCO Finland
Curettage of uterus after abortion
3.1
9.1
49
162
O86.1
ICD-10 Finland
Other infection of genital tract following delivery
3.7
9.1
38
104
L02BG04
ATC
letrozole; oral
1.7
9.0
198
1219
F29
ICD-10 Finland
Unspecified nonorganic psychosis
0.4
8.9
41
957
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
8.8
2052
18586
LCH11
NOMESCO Finland
Pharmacologic abortion
1.6
8.8
203
1262
O03.0
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by genital tract and pelvic infection
3.5
8.8
39
112
G02BA03
ATC
plastic IUD with progestogen
1.3
8.8
748
6013
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
3.5
8.7
38
108
O34.4
ICD-10 Finland
Maternal care for other abnormalities of cervix
50.1
8.7
10
*
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
1.8
8.7
152
875
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
1.4
8.7
502
3806
SPAT1315
SPAT
Periodic health check-up of children and adolescents
1.9
8.6
118
625
O26.9
ICD-10 Finland
Pregnancy-related condition, unspecified
4.5
8.6
29
65
SPAT1383
SPAT
Extensive health check-up at 4 years of age
3.3
8.6
42
130
W30
ICPC
Pregnancy, Medical examin/health eval complete
4.1
8.6
32
79
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.5
8.6
64
259
L02AE03
ATC
goserelin; implant
2.6
8.6
62
244
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
1.9
8.5
128
700
O64.0
ICD-10 Finland
Obstructed labour due to incomplete rotation of fetal head
2.2
8.4
80
365
O21.1
ICD-10 Finland
Hyperemesis gravidarum with metabolic disturbance
5.4
8.4
24
45
F20.9
ICD-10 Finland
Schizophrenia, unspecified
0.2
8.4
7
381
6500B
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
0.8
8.4
606
7526
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
8.3
2357
21740
MAJ00
NOMESCO Finland
Reduction of multiple pregnancy by one foetus
+∞
8.3
8
*
Z37.5
ICD-10 Finland
Other multiple births, all liveborn
+∞
8.3
8
*
6584B
ICD-9 Finland
Other problems associated with amniotic cavity and membranes, Infection of amniotic cavity[AMNIONITIS, SYNNYTYKSEN AIKANA]
+∞
8.3
8
*
MAA54
NOMESCO Finland
Fetoscopy
+∞
8.3
8
*
O45.8
ICD-10 Finland
Other premature separation of placenta
+∞
8.3
8
*
O36.2
ICD-10 Finland
Maternal care for hydrops fetalis
+∞
8.3
8
*
O91.2
ICD-10 Finland
Nonpurulent mastitis associated with childbirth
2.9
8.3
48
166
O68.8
ICD-10 Finland
Labour and delivery complicated by other evidence of fetal stress
3.1
8.1
43
142
SGA01
NOMESCO Finland
Tooth opening as first aid
1.3
8.1
560
4361
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
1.5
8.1
254
1709
M01AE01
ATC
ibuprofen; systemic, rectal
1.4
8.1
3320
32003
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
2.3
8.0
72
321
SPAT1382
SPAT
Extensive health check-up at 18 months of age
4.1
8.0
29
71
F43.00
ICD-10 Finland
Acute stress reaction mild
1.9
7.9
118
647
V230A
ICD-9 Finland
Supervision of high-risk pregnancy, Pregnancy with history of infertility
2.7
7.8
51
192
A11JC
ATC
Vitamins, other combinations
45.1
7.7
9
*
MCA00
NOMESCO Finland
Upper uterine segment caesarean section
15.0
7.7
12
8
O69.8
ICD-10 Finland
Labour and delivery complicated by other cord complications
15.0
7.7
12
8
SPAT1301
SPAT
No procedures
1.3
7.6
758
6212
N05AX08
ATC
risperidone; systemic
0.5
7.5
71
1311
Z32
ICD-10 Finland
Pregnancy examination and test
3.1
7.5
38
122
SPAT1325
SPAT
Vaccination
1.3
7.5
684
5538
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
7.5
1169
10088
Z39
ICD-10 Finland
Postpartum care and examination
2.6
7.4
50
193
WX110
NOMESCO Finland
Local anesthesy
1.2
7.4
2388
22171
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.7
7.4
156
948
O64.5
ICD-10 Finland
Obstructed labour due to compound presentation
80.2
7.4
8
*
E66.9
ICD-10 Finland
Obesity, unspecified
1.8
7.4
117
652
W03
ICPC
Antepartum bleeding
3.2
7.4
36
113
6173B
ICD-9 Finland
Endometriosis of pelvic peritoneum[ENDOMETRIOSIS RETROUTERINA]
3.0
7.4
39
130
WX600
NOMESCO Finland
Single shot through catheter
2.2
7.3
67
302
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
0.2
7.3
7
352
6545A
ICD-9 Finland
Abnormality of organs and soft tissues of pelvis, Cervical incompetence[INSUFFICIENTIA CERVICIS UTERI, RASKAUDEN AIKANA]
+∞
7.3
7
*
O36.1
ICD-10 Finland
Maternal care for other isoimmunization
+∞
7.3
7
*
O34.8
ICD-10 Finland
Maternal care for other abnormalities of pelvic organs
+∞
7.3
7
*
6565A
ICD-9 Finland
Other foetal and placental problems affecting management of mother, Poor foetal growth[SIKIÖN HIDASTUNUT INTRAUTERIININ KASVU,RASK AIK]
4.1
7.3
26
63
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
0.7
7.3
264
3628
SPAT1381
SPAT
Extensive health check-up at 4 months of age
3.9
7.2
28
73
G03DC02
ATC
norethisterone; oral
1.4
7.2
338
2469
O62.1
ICD-10 Finland
Secondary uterine inertia
2.8
7.2
43
155
O99.7
ICD-10 Finland
Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
5.3
7.1
20
38
A77
ICPC
Viral disease other/NOS
1.7
7.1
129
757
MBA20
NOMESCO Finland
Expression of placenta
3.9
7.0
27
70
O00.1
ICD-10 Finland
Tubal pregnancy
2.0
7.0
86
438
P72
ICPC
Schizophrenia
0.2
7.0
7
340
1350
FHL
Hysteroscopy
3.4
7.0
32
96
Z30.0
ICD-10 Finland
General counselling and advice on contraception
1.4
7.0
308
2225
O73.1
ICD-10 Finland
Retained portions of placenta and membranes, without haemorrhage
3.1
7.0
36
118
W28
ICPC
Limited function/disability (W)
7.0
7.0
16
23
W18
ICPC
Post-partum symptom/complaint other
4.1
7.0
25
61
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
0.1
7.0
*
279
LA2JE
NOMESCO Finland
Follow-up of menstrual cycle with repeated measurement of ovarian cyst
2.8
6.9
41
147
8221
FHL
Sterilization of the laparotomy pathway
2.0
6.9
87
448
OAA11
SPAT
NA
1.9
6.8
95
511
J01CA04
ATC
amoxicillin; systemic
1.2
6.8
2886
27422
MCA30
NOMESCO Finland
Supravaginal caesarean hysterectomy
40.1
6.8
8
*
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.4
6.7
315
2303
MBC30
NOMESCO Finland
Repair of partial rupture of perineum
2.0
6.7
84
434
62800
ICD-8 Finland
Sterility, female, Sterilitas primaria
3.8
6.6
26
69
J03.8
ICD-10 Finland
Acute tonsillitis due to other specified organisms
6.4
6.6
16
25
R2110
NOMESCO Finland
Giving the first information
1.5
6.6
239
1663
N05AB03
ATC
perphenazine; systemic, rectal
0.4
6.6
29
686
N05AH02
ATC
clozapine; systemic
0.3
6.5
12
418
WW500
NOMESCO Finland
Blood transfusion
2.0
6.5
76
384
W99
ICPC
Disorder of pregn/delivery other
5.0
6.5
19
38
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
1.9
6.5
86
455
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
1.8
6.4
108
618
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
2.2
6.4
60
275
6171A
ICD-9 Finland
Endometriosis of ovary
2.8
6.3
37
131
WX234
NOMESCO Finland
Paracervical blockade
1.7
6.3
115
672
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.2
6.3
1866
17048
6563B
ICD-9 Finland
Other foetal and placental problems affecting management of mother, Foetal distress[ASPHYXIA FOETALIS, SYNNYTYKSEN AIKANA]
1.9
6.3
83
438
KAY40
NOMESCO Finland
NA
0.4
6.3
24
598
O75.7
ICD-10 Finland
Vaginal delivery following previous caesarean section
9.3
6.3
12
13
N05AX12
ATC
aripiprazole; systemic
0.5
6.3
63
1141
63495
ICD-8 Finland
Other complications of pregnancy, Effluxus liquoris amnii praetemporarius
+∞
6.2
6
*
6584A
ICD-9 Finland
Other problems associated with amniotic cavity and membranes, Infection of amniotic cavity[AMNIONITIS, RASKAUDEN AIKANA]
+∞
6.2
6
*
6411B
ICD-9 Finland
Antepartum haemorrhage, abruptio placentae and placenta praevia, Haemorrhage from placenta praevia[PLACENTA PRAEVIA CUM HAEMORRHAGIA,SYNN PÄÄTT HOITOJ]
+∞
6.2
6
*
O32.8
ICD-10 Finland
Maternal care for other malpresentation of fetus
+∞
6.2
6
*
O34.7
ICD-10 Finland
Maternal care for abnormality of vulva and perineum
+∞
6.2
6
*
O33.0
ICD-10 Finland
Maternal care for disproportion due to deformity of maternal pelvic bones
+∞
6.2
6
*
MAA06
NOMESCO Finland
Amnioreduction
+∞
6.2
6
*
6424A
ICD-9 Finland
Hypertension complicating pregnancy, childbirth and the puerperium, Mild or unspecified pre-eclampsia[PRAE-ECLAMPSIA LEVIS, ENNEN SYNNYTYSTÄ]
2.2
6.2
57
259
XX2XT
NOMESCO Finland
Other injection with other radiological guidance
5.0
6.2
18
36
LGA00
NOMESCO Finland
Sterilisation by ligature of Fallopian tubes
3.6
6.2
25
69
MA3AE
SPAT
NA
5.3
6.1
17
32
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.2
6.1
1760
16024
O61.1
ICD-10 Finland
Failed instrumental induction of labour
7.7
6.1
13
17
J01AA02
ATC
doxycycline; systemic
1.2
6.1
2570
24215
O67.9
ICD-10 Finland
Intrapartum haemorrhage, unspecified
4.7
6.1
19
41
N05BA06
ATC
lorazepam; systemic, sublingual
0.4
6.0
30
678
MCA96
NOMESCO Finland
Other caesarean section
10.0
6.0
11
11
WZB00
SPAT
NA
0.5
6.0
57
1048
B02AA02
ATC
tranexamic acid; systemic
1.3
6.0
634
5221

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
207
595
3.61
60.85
2.5
2.0
6.9
5.8
umol/l
0.68
161
450
936
5759
1.81
50.57
1.7
1.6
—
—
—
0
0
1142
7721
1.67
42.91
1.8
1.7
—
—
—
0
0
395
2000
2.08
37.43
1.5
1.3
—
—
—
0
0
693
4324
1.73
34.15
2.2
1.8
—
—
—
0
0
1811
14938
1.38
21.85
4.3
3.5
—
—
—
0
0
52
120
4.38
20.81
3.2
2.1
—
—
—
0
0
1260
9926
1.39
19.49
2.0
2.0
—
—
—
0
0
101
387
2.65
18.21
1.5
1.4
7.8
7.7
mmol/l
0.21
69
229
1191
9464
1.37
16.96
2.1
1.9
—
—
—
0
0
2342
20639
1.32
15.97
3.9
3.5
234.7
1713.0
e6/l
2.86
15
229
456
3106
1.53
14.90
2.4
2.0
8073.7
4565.4
u/l
1.35
192
1122
990
8004
1.31
11.75
2.4
2.2
—
—
—
0
0
2424
22015
1.25
10.56
3.9
3.7
—
—
—
0
0
373
2616
1.47
10.49
3.3
3.2
—
—
—
0
0
870
7005
1.31
10.48
2.0
1.9
—
—
—
0
0
259
1686
1.57
10.35
1.6
1.4
—
—
—
0
0
1784
15728
1.24
9.95
3.7
3.8
6.2
6.3
mmol/l
0.35
1596
14560
997
8424
1.24
7.79
4.0
4.9
1.0
1.1
inr
1.71
365
2821
441
3354
1.35
7.76
1.8
2.2
28.5
29.3
s
2.68
424
3244
122
711
1.74
7.59
2.5
1.8
1.1
1.4
g/l
3.92
110
607
916
7697
1.25
7.48
1.8
1.7
1.0
0.8
mg/l
3.17
719
5748
144
887
1.65
7.31
1.1
1.1
—
—
—
0
0
46
192
2.41
7.16
1.3
1.2
—
—
—
0
0
1190
10380
1.21
6.63
2.0
1.5
—
—
—
0
0
957
8179
1.22
6.56
3.6
3.2
0.0
0.0
estimate
0.39
406
2959
184
1263
1.48
5.86
1.6
2.0
20.6
20.7
s
0.06
159
1053
114
706
1.63
5.75
1.3
1.4
—
—
—
0
0
818
6994
1.21
5.48
2.6
2.7
0.3
0.3
e6/l
0.23
626
5066
3780
36910
1.34
5.33
9.9
9.0
—
—
—
0
0
585
4852
1.24
5.25
2.3
2.5
518.7
527.1
mosm/kgh2o
0.34
509
4115
636
5327
1.23
5.21
2.2
2.3
8.6
8.8
e6/l
0.10
558
4623
39
176
2.23
5.18
1.2
1.2
—
—
—
0
0
1754
16078
1.16
5.06
4.5
4.2
0.0
0.0
estimate
1.34
411
3014
1763
16197
1.16
4.87
3.4
3.0
0.0
0.0
estimate
0.56
412
2939
423
3421
1.26
4.74
1.7
1.7
—
—
—
0
0
191
1382
1.40
4.65
1.7
1.7
—
—
—
0
0
1740
16008
1.15
4.64
3.3
3.0
0.0
0.0
estimate
0.50
398
2883
235
1765
1.35
4.56
1.3
1.3
—
—
—
0
0
816
7097
1.19
4.46
2.6
2.6
—
—
—
0
0
812
7081
1.18
4.30
2.1
1.9
498.5
2349.2
umol/l
6.44
744
6400
154
1089
1.43
4.30
2.5
2.8
—
—
—
0
0
76
465
1.65
4.13
2.5
2.5
—
—
—
0
0
881
7764
1.17
4.09
2.6
2.8
43.2
79.7
e6/l
1.37
673
5775
436
3603
1.24
4.05
1.8
1.9
—
—
—
0
0
1577
14543
1.14
3.84
7.7
8.0
0.0
0.0
e9/l
0.76
1334
11914
2032
19051
1.13
3.81
3.1
2.9
70.7
67.9
ug/l
0.20
1942
18288
3408
33098
1.18
3.76
8.9
9.4
3.9
3.9
mmol/l
1.27
3332
32220
3393
32977
1.17
3.53
8.9
9.3
139.6
139.6
mmol/l
0.17
3328
32175
3545
34604
1.19
3.38
10.1
9.8
18.1
17.9
mg/l
0.18
2762
26064
98
670
1.47
3.34
1.3
1.4
100.3
109.3
u/ml
0.48
26
143
997
9020
1.14
3.15
2.2
2.5
58.4
56.0
u/l
0.22
946
8413
1044
9476
1.14
3.14
2.8
2.6
—
—
—
0
0
149
1122
1.34
2.96
2.1
2.1
3.5
4.4
iu/l
0.74
66
516
1101
10063
1.13
2.94
3.0
3.2
67.0
63.8
e6/l
0.08
743
6453
479
4126
1.18
2.92
2.5
2.7
356.8
321.2
ng/l
0.09
222
2066
274
2237
1.24
2.91
1.1
1.1
302.1
158.0
titre
—
7
64
1595
14911
1.11
2.86
5.0
5.3
9.4
9.4
umol/l
0.03
1504
14090
796
7146
1.14
2.81
1.3
1.3
8.2
10.1
u/ml
0.39
356
3170
46
277
1.67
2.76
1.1
1.2
1.0
1.0
ratio
0.36
21
106
231
1877
1.24
2.59
2.7
2.3
—
—
—
0
0
3131
30438
1.12
2.55
11.6
12.1
13.5
13.5
%
0.26
3088
29893
6
11
5.46
2.54
1.5
1.4
—
—
—
0
0
101
736
1.38
2.52
2.8
3.1
0.5
0.3
g/l
0.42
44
285
85
610
1.40
2.34
1.9
1.9
—
—
—
0
0
34
201
1.70
2.24
1.3
1.4
5.6
6.5
mmol/l
1.15
27
141
11
257
0.43
2.21
1.5
1.5
—
—
—
0
0
3969
39361
1.33
2.17
14.9
14.8
30.0
30.0
pg
0.13
3954
39054
27
151
1.79
2.15
2.7
2.9
10.4
8.2
mg/l
0.34
20
115
3971
39390
1.32
2.11
15.1
14.9
132.9
133.8
g/l
6.27
3953
39081
3969
39369
1.32
2.09
15.0
14.8
4.5
4.5
e12/l
4.17
3916
38664
32
190
1.69
2.09
2.4
2.3
—
—
—
0
0
3968
39364
1.31
2.03
15.0
14.8
90.1
90.2
fl
1.21
3952
39059
63
441
1.44
2.03
1.3
1.2
—
—
—
0
0
25
140
1.79
2.00
2.3
2.5
155.6
84.8
au/ml
—
5
23
3969
39379
1.31
2.00
15.1
14.9
6.7
6.6
e9/l
2.11
3911
38637
3030
29528
1.10
1.99
4.5
4.3
14.2
14.2
pmol/l
0.08
2922
28040
3964
39325
1.30
1.98
15.1
14.9
265.5
274.0
e9/l
15.68
3920
38653
1000
10734
0.91
1.88
1.8
1.8
98.1
100.3
pmol/l
0.83
577
5811
101
1304
0.77
1.87
1.9
2.4
0.2
0.2
e6/l
0.01
94
1236
350
3060
1.16
1.84
2.2
2.6
34.5
34.7
u/ml
0.01
338
2965
7
23
3.05
1.80
2.9
1.7
262.0
310.9
umol/24h
—
7
23
92
703
1.32
1.78
3.2
4.9
1.7
1.8
%
0.22
84
662
932
8661
1.10
1.76
2.3
2.3
21.0
27.3
ng/l
0.61
354
3401
112
883
1.28
1.72
2.0
2.4
13.2
13.2
%
0.02
112
874
595
5413
1.12
1.70
3.7
3.8
—
—
—
0
0
5
14
3.57
1.61
1.0
1.4
—
—
—
0
0
95
1208
0.78
1.61
1.7
1.8
—
—
—
0
0
3699
36534
1.14
1.58
8.3
8.4
24.8
24.2
u/l
0.90
3627
35711
760
7035
1.10
1.56
3.1
3.0
7.6
7.6
mmol/l
0.12
680
6132
1013
9505
1.09
1.54
1.3
1.3
1.6
1.5
u/ml
0.07
338
2826
71
536
1.33
1.53
1.5
1.5
—
—
—
0
0
90
705
1.28
1.49
3.4
5.0
0.9
1.0
%
0.67
83
665
721
6676
1.10
1.48
3.4
3.1
1.0
1.0
kg/l
0.50
118
916
1398
14668
0.93
1.48
2.2
2.3
73.6
74.4
nmol/l
0.64
1328
13881
1581
15136
1.07
1.41
2.2
2.2
—
—
—
0
0
61
457
1.34
1.41
2.9
3.1
—
—
—
0
0
255
2230
1.15
1.40
1.6
1.8
—
—
—
0
0
60
449
1.34
1.40
2.4
1.9
132.2
130.7
g/l
0.24
48
315
85
669
1.28
1.38
1.1
1.2
—
—
—
0
0
46
332
1.39
1.34
2.7
2.4
7.2
6.9
mmol/l
0.21
46
326
769
7180
1.09
1.31
3.3
3.0
—
—
—
0
0
253
2224
1.15
1.31
1.5
1.8
—
—
—
0
0
20
121
1.66
1.30
2.1
2.0
—
—
—
0
0
151
1782
0.84
1.30
3.0
3.7
63.2
79.2
ng/l
3.32
140
1611
255
2244
1.15
1.30
1.6
1.7
—
—
—
0
0
590
5449
1.10
1.29
1.6
1.6
—
—
—
0
0
5
18
2.78
1.28
1.0
1.1
—
—
—
0
0
411
4521
0.90
1.28
2.3
2.4
2.4
2.4
mmol/l
0.04
352
3955
226
1975
1.15
1.27
1.1
1.1
—
—
—
0
0
175
1502
1.17
1.25
2.9
2.3
—
—
—
0
0
5
118
0.42
1.24
1.0
1.3
—
—
—
0
0
255
2254
1.14
1.23
1.6
1.8
—
—
—
0
0
1221
11637
1.07
1.22
2.7
3.0
30.0
28.7
u/l
0.17
1163
11164
1705
17668
0.94
1.19
5.1
5.9
2.0
2.0
e9/l
0.52
1563
16077
2528
25877
0.94
1.18
2.7
2.8
32.9
33.7
u/l
0.32
2438
24946
3365
33171
1.08
1.17
5.1
4.9
1.6
2.2
mu/l
3.03
3246
31785
455
4173
1.10
1.17
2.2
2.4
1.2
1.1
e6/l
0.24
244
2208
85
687
1.24
1.15
1.3
1.2
3.8
3.7
u/ml
0.04
42
277
5
20
2.50
1.15
1.6
1.1
15.6
17.7
umol/l
—
5
20
22
142
1.55
1.14
2.1
2.0
—
—
—
0
0
516
5577
0.91
1.14
1.5
1.4
20.6
21.1
nmol/l
0.46
472
5038
1590
16492
0.94
1.13
5.0
5.8
56.2
56.2
%
0.10
1511
15676
765
7189
1.08
1.13
1.9
2.0
116.9
135.7
u/l
0.81
731
6859
793
7463
1.08
1.12
1.3
1.3
16.4
23.7
iu/ml
4.11
298
2374
2419
23602
1.06
1.11
6.2
6.7
72.0
72.4
u/l
0.19
2309
22414
283
2540
1.12
1.10
1.3
1.3
25.6
38.3
au/ml
—
7
109
5
21
2.38
1.09
4.2
3.0
—
—
—
0
0
793
7473
1.08
1.09
2.2
2.2
2.6
2.7
mg/l
0.82
694
6515
53
408
1.30
1.07
2.6
3.0
29.9
33.1
umol/l
0.55
42
364
154
1331
1.16
1.05
1.1
1.1
6.4
3.7
u/ml
0.45
26
252
25
170
1.47
1.04
1.4
1.7
2.6
2.1
u/field
0.19
19
92
81
661
1.23
1.03
3.6
5.2
1.1
1.3
mmol/l
1.19
72
587
5
22
2.27
1.03
4.0
2.8
—
—
—
0
0
1483
15378
0.94
1.03
5.3
6.1
0.7
0.7
%
0.00
1402
14501
631
5911
1.08
1.02
4.1
3.9
14.8
9.3
mg/mmol
1.80
401
3646
1614
16691
0.95
1.01
5.1
6.0
30.2
30.1
%
0.30
1530
15837
787
7439
1.07
1.00
3.2
3.4
100.8
99.8
%
0.68
760
7204
36
265
1.36
0.99
1.1
1.2
—
—
—
0
0
55
432
1.28
0.98
2.3
2.9
1.8
2.4
mmol/l
1.00
29
286
7
36
1.95
0.97
1.3
1.1
—
—
—
0
0
213
1897
1.13
0.96
1.0
1.1
—
—
—
0
0
2543
24905
1.06
0.95
3.7
3.7
9.0
9.7
mm/h
2.84
2430
23590
133
1148
1.16
0.94
1.2
1.3
—
—
—
0
0
302
2748
1.11
0.94
2.3
2.3
17.3
26.3
au/ml
1.08
20
221
9
51
1.77
0.94
1.0
1.1
—
—
—
0
0
11
62
1.78
0.94
1.1
1.1
—
—
—
0
0
7
37
1.89
0.94
2.7
2.9
—
—
—
0
0
514
4795
1.08
0.93
1.3
1.3
30.0
29.0
iu/l
0.25
456
4174
70
570
1.23
0.93
3.4
3.2
20.0
20.8
mg/l
0.09
42
346
23
158
1.46
0.93
1.3
2.5
197.8
154.2
umol/l
—
8
87
1541
15910
0.95
0.89
5.2
6.0
2.9
2.8
%
0.96
1453
15009
143
1632
0.87
0.88
6.6
7.8
7.0
7.1
mmol/l
0.02
137
1577
36
272
1.33
0.87
1.3
1.2
—
—
—
0
0
82
975
0.84
0.85
2.0
2.2
8.8
10.1
mg/l
1.24
75
915
603
5683
1.07
0.85
3.2
3.2
401.6
482.3
mg/l
0.16
377
3378
639
6035
1.07
0.85
1.5
1.4
—
—
—
0
0
333
3066
1.09
0.84
3.6
3.5
4.5
4.5
pmol/l
0.08
311
2757
199
1784
1.12
0.84
1.4
1.3
—
—
—
0
0
8
46
1.74
0.82
1.3
1.0
—
—
—
0
0
47
372
1.27
0.82
2.2
2.3
17.4
16.8
%
0.41
20
189
6
32
1.88
0.81
1.0
1.2
—
—
—
0
0
193
2147
0.89
0.81
7.6
10.0
1.0
1.1
inr
3.23
34
378
26
189
1.38
0.80
2.3
1.9
—
—
—
0
0
1650
16972
0.95
0.80
5.1
6.0
0.5
0.5
e9/l
2.42
1483
15188
1656
17031
0.95
0.80
5.2
6.0
0.0
0.0
e9/l
0.46
1489
15196
94
803
1.17
0.79
3.5
3.5
0.7
0.7
%
0.28
87
773
9
151
0.60
0.78
3.2
2.9
—
—
—
0
0
77
649
1.19
0.77
1.1
1.0
—
—
—
0
0
142
1602
0.88
0.76
8.1
8.7
—
—
—
0
0
9
53
1.70
0.75
1.2
1.2
—
—
—
0
0
9
53
1.70
0.75
3.4
2.2
—
—
—
0
0
9
54
1.67
0.74
1.1
1.4
23.6
63.1
mu/l
—
9
40
187
1687
1.11
0.73
1.8
1.9
—
—
—
0
0
7
38
1.84
0.73
1.3
1.4
63.4
87.7
ng/l
—
7
38
125
1416
0.88
0.73
1.6
1.3
3.8
3.0
ug/l
0.82
117
1280
88
757
1.17
0.71
1.5
1.6
—
—
—
0
0
25
186
1.35
0.70
2.3
2.1
20.5
60.4
ug/l
0.51
25
178
454
4274
1.07
0.69
1.2
1.2
—
—
—
0
0
11
69
1.60
0.68
3.0
1.4
—
—
—
0
0
216
1974
1.10
0.68
3.3
3.3
1.2
1.2
mmol/l
1.21
192
1751
48
392
1.23
0.68
1.5
1.3
—
—
—
0
0
1726
17680
0.96
0.67
5.1
6.3
0.2
0.2
e9/l
0.30
1570
16027
7
117
0.60
0.67
2.9
1.6
—
—
—
0
0
164
1479
1.11
0.66
1.3
1.2
11.0
12.4
u/l
0.80
143
1208
421
3959
1.07
0.66
1.2
1.2
138.2
153.9
iu/ml
0.43
168
1615
223
2044
1.10
0.66
1.7
1.8
—
—
—
0
0
59
494
1.20
0.66
2.4
2.3
—
—
—
0
0
52
430
1.21
0.66
2.5
2.8
—
—
—
0
0
94
820
1.15
0.65
3.7
3.6
1.5
1.4
%
0.32
94
810
1558
15980
0.96
0.64
5.4
6.3
7.7
7.9
%
1.59
1485
15205
932
9668
0.95
0.64
2.9
3.2
2.3
2.3
mmol/l
2.15
855
8839
61
514
1.19
0.64
2.3
3.0
7.4
7.4
ph
0.10
54
426
246
2272
1.09
0.63
3.5
4.2
0.7
0.6
%
0.24
50
405
42
513
0.82
0.62
1.1
1.1
—
—
—
0
0
371
3484
1.07
0.62
2.2
2.4
7.6
6.0
umol/l
0.59
314
2928
95
1081
0.88
0.62
1.1
1.3
—
—
—
0
0
38
306
1.24
0.62
1.1
1.1
17.2
7.4
iu/ml
—
7
99
23
302
0.76
0.62
1.3
1.2
—
—
—
0
0
63
739
0.85
0.61
1.0
1.3
—
—
—
0
0
5
30
1.67
0.61
1.0
1.2
—
—
—
0
0
239
2208
1.09
0.61
1.3
1.3
245.6
233.4
miu/ml
0.21
125
1162
145
1605
0.90
0.60
1.7
1.7
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
0.0
—
0
15
59
694
0.85
0.60
2.6
3.3
162.6
308.5
u/ml
0.25
47
599
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
28
355
0.79
0.59
1.0
1.1
—
—
—
0
0
88
771
1.14
0.59
1.3
1.2
261.0
269.2
u/ml
0.10
61
520
1559
15221
1.04
0.58
2.0
2.0
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
50
594
0.84
0.57
8.4
3.5
1.2
1.3
mmol/l
0.63
50
583
258
2400
1.08
0.57
1.3
1.2
—
—
—
0
0
11
161
0.68
0.57
2.5
3.3
—
—
—
0
0
1897
19336
0.96
0.55
7.2
9.1
4.0
3.9
e9/l
0.54
1702
17217
47
394
1.20
0.54
1.4
1.4
—
—
—
0
0
8
122
0.66
0.54
1.0
1.1
—
—
—
0
0
132
1194
1.11
0.54
2.0
2.3
54.8
87.4
ng/l
2.07
116
1070
6
38
1.58
0.54
1.8
1.7
—
—
—
0
0
19
142
1.34
0.54
2.5
2.0
2088.4
1960.8
ml
0.23
19
136
83
941
0.88
0.54
4.6
4.9
23.5
24.3
mmol/l
1.19
72
858
15
204
0.73
0.52
1.1
1.7
43.0
36.3
%
—
10
120
16
117
1.37
0.52
1.0
1.1
—
—
—
0
0
273
2557
1.07
0.52
1.4
1.7
284.9
335.3
mu/l
2.01
243
2275
155
1418
1.10
0.52
1.3
1.4
30.9
27.8
u/l
0.49
134
1160
155
1419
1.10
0.51
1.2
1.2
—
—
—
0
0
863
8917
0.96
0.51
3.7
3.9
—
—
—
0
0
13
92
1.41
0.50
1.0
1.5
—
—
—
0
0
90
801
1.13
0.50
1.1
1.1
2.7
2.4
u/ml
0.19
45
480
6
41
1.46
0.50
1.2
1.2
—
—
—
0
0
3220
32474
0.96
0.50
3.1
3.1
1.2
1.2
mmol/l
2.26
3100
31223
345
3645
0.94
0.49
1.4
1.4
—
—
—
0
0
18
136
1.32
0.49
1.2
1.1
—
—
—
0
0
32
388
0.82
0.48
1.5
1.5
313.6
358.6
pmol/l
0.31
25
315
252
2686
0.93
0.48
1.8
2.4
3.9
4.0
e9/l
0.40
218
2308
219
2346
0.93
0.48
2.3
2.2
0.2
0.2
g/l
0.09
211
2229
463
4424
1.05
0.47
2.1
2.3
15.1
14.6
umol/l
0.88
428
4147
813
8394
0.96
0.47
5.2
6.9
—
—
—
0
0
18
137
1.32
0.47
1.0
1.1
—
—
—
0
0
7
48
1.46
0.46
1.0
1.1
—
—
—
0
0
100
1108
0.90
0.46
10.3
9.0
0.7
0.7
%
0.18
100
1102
59
675
0.87
0.46
1.2
1.2
—
—
—
0
0
67
590
1.14
0.45
1.5
1.6
0.6
0.6
g/l
0.38
55
441
12
164
0.73
0.45
1.2
1.1
—
—
—
0
0
25
201
1.25
0.44
2.5
3.2
—
—
—
0
0
20
253
0.79
0.44
1.8
1.5
1.0
1.1
promille
0.20
14
195
7
51
1.37
0.44
1.1
1.6
—
—
—
0
0
13
95
1.37
0.43
1.1
1.1
—
—
—
0
0
25
307
0.81
0.43
6.0
3.1
—
—
—
0
0
1177
11495
1.03
0.43
4.0
4.3
36.5
37.0
g/l
2.44
1108
10810
9
128
0.70
0.43
2.4
2.2
—
—
—
0
0
9
130
0.69
0.43
1.2
1.2
—
—
—
0
0
69
775
0.89
0.42
1.6
1.3
—
—
—
0
0
20
158
1.27
0.41
1.5
1.6
—
6.9
—
0
15
63
557
1.13
0.41
1.1
1.1
—
—
—
0
0
251
2369
1.06
0.41
3.8
4.5
0.1
0.2
%
0.12
55
515
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
2.0
—
—
—
0
0
19
238
0.80
0.40
2.0
3.0
871.8
888.8
e6/l
—
8
106
0
18
0.00
0.40
0.0
1.1
—
108.1
—
0
18
208
1955
1.07
0.39
3.1
3.1
—
—
—
0
0
8
61
1.31
0.39
1.0
1.1
—
—
—
0
0
34
400
0.85
0.39
1.2
1.2
—
—
—
0
0
7
105
0.67
0.39
1.1
1.2
—
—
—
0
0
22
270
0.81
0.39
2.2
2.8
579.9
503.5
e6/l
0.58
17
222
7
106
0.66
0.39
1.1
1.1
—
—
—
0
0
7
106
0.66
0.39
1.1
1.1
—
—
—
0
0
7
106
0.66
0.39
1.1
1.1
—
—
—
0
0
78
864
0.90
0.38
1.1
1.1
0.8
4.2
u/ml
2.50
32
312
25
302
0.83
0.38
1.2
1.2
—
—
—
0
0
45
391
1.15
0.38
1.4
1.3
3.2
3.0
g/l
0.44
33
271
19
151
1.26
0.38
1.2
1.2
—
—
—
0
0
102
1114
0.91
0.38
10.2
8.9
94.9
94.2
%
0.68
102
1109
242
2291
1.06
0.37
3.9
4.5
0.0
0.2
%
0.59
51
438
45
392
1.15
0.37
1.4
1.3
6.5
6.4
g/l
0.10
33
273
45
392
1.15
0.37
1.4
1.3
0.4
0.3
g/l
0.70
34
272
381
3972
0.96
0.37
1.6
1.7
—
—
—
0
0
15
191
0.78
0.36
1.5
1.7
—
—
—
0
0
28
332
0.84
0.36
1.3
1.3
—
—
—
0
0
97
1058
0.91
0.36
8.0
6.5
—
—
—
0
0
602
5833
1.04
0.36
1.4
1.4
600.6
556.0
titre
0.18
127
1215
64
713
0.90
0.36
3.3
3.2
1.3
1.3
mg/l
0.09
59
675
5
78
0.64
0.35
1.2
1.1
—
—
—
0
0
5
78
0.64
0.35
1.2
1.1
—
—
—
0
0
5
78
0.64
0.35
1.2
1.1
—
—
—
0
0
20
162
1.24
0.35
1.2
1.2
—
—
—
0
0
6
43
1.40
0.35
1.2
1.2
—
—
—
0
0
102
939
1.09
0.34
1.8
2.3
—
—
—
0
0
276
2633
1.05
0.34
1.3
1.2
—
—
—
0
0
92
1001
0.92
0.33
1.1
1.1
0.1
1.4
u/ml
6.04
16
234
259
2468
1.05
0.33
3.8
4.4
0.7
0.8
%
0.38
58
554
6
46
1.30
0.33
1.0
1.2
—
—
—
0
0
88
957
0.92
0.32
8.0
9.2
23.7
24.1
mmol/l
0.49
83
907
368
3541
1.04
0.32
2.1
2.4
26.0
24.0
%
1.50
323
3093
525
5415
0.97
0.32
2.4
2.4
102.7
97.8
ug/g
0.15
426
4274
23
273
0.84
0.31
2.9
1.6
—
—
—
0
0
7
52
1.35
0.31
2.1
7.8
—
—
—
0
0
7
53
1.32
0.30
1.4
1.3
—
—
—
0
0
7
98
0.71
0.30
1.3
1.4
—
—
—
0
0
102
946
1.08
0.30
1.3
1.3
127.1
169.3
titre
—
7
92
135
1266
1.07
0.30
2.2
2.1
—
—
—
0
0
22
261
0.84
0.30
1.2
1.1
—
—
—
0
0
7
55
1.27
0.30
1.3
1.3
—
—
—
0
0
76
697
1.09
0.29
1.3
1.2
—
—
—
0
0
1303
12820
1.02
0.29
5.0
5.6
1.2
1.2
mmol/l
1.65
1113
10941
8
107
0.75
0.29
1.0
1.0
—
—
—
0
0
3205
32231
0.97
0.28
12.0
12.5
332.2
331.6
g/l
2.40
3189
31985
8
111
0.72
0.28
1.6
1.4
38.8
36.8
g/l
—
8
102
37
326
1.14
0.28
1.3
1.3
0.1
0.9
u/ml
0.71
14
135
36
408
0.88
0.28
4.6
3.0
53.7
43.1
mg/l
0.13
27
333
84
776
1.08
0.28
1.4
1.4
348.7
312.3
ug/g
0.78
43
402
151
1427
1.06
0.28
2.4
2.2
66.9
67.7
g/l
0.78
145
1340
241
2516
0.96
0.27
3.0
2.6
10.2
10.5
g/l
0.77
230
2344
121
1136
1.07
0.27
1.3
1.3
8.7
8.7
u/ml
0.00
19
196
136
1282
1.06
0.27
1.1
1.2
—
—
—
0
0
64
699
0.91
0.27
2.2
2.6
24.6
24.6
mmol/l
0.08
58
658
2097
20758
1.02
0.27
2.6
2.6
—
—
—
0
0
417
4043
1.03
0.26
3.0
3.2
0.8
0.8
mmol/l
0.38
397
3832
87
808
1.08
0.26
2.0
2.6
—
—
—
0
0
349
3375
1.04
0.26
1.3
1.3
—
—
—
0
0
85
914
0.93
0.26
1.6
1.3
512.5
434.1
mg/l
0.75
85
875
64
696
0.92
0.25
1.1
1.1
0.0
0.4
u/ml
0.88
12
134
407
3950
1.03
0.25
2.0
2.3
2.5
2.5
g/l
0.65
370
3694
23
266
0.86
0.24
1.0
1.1
281.5
304.0
mg/l
1.22
23
239
17
142
1.20
0.24
2.3
2.4
0.5
1.2
ug/l
2.34
17
135
369
3578
1.03
0.24
1.4
1.5
—
—
—
0
0
799
8140
0.98
0.23
1.5
1.4
2.0
2.1
g/l
1.62
524
5380
112
1057
1.06
0.23
5.9
4.6
—
—
—
0
0
68
630
1.08
0.23
2.4
2.4
—
—
—
0
0
162
1697
0.95
0.23
8.2
7.9
119.2
121.0
g/l
0.58
155
1638
23
264
0.87
0.23
4.0
3.0
4.4
3.7
nmol/l
0.14
23
255
131
1243
1.06
0.23
1.3
1.3
2.4
42.2
u/ml
—
5
102
104
1103
0.94
0.22
10.0
9.0
1.4
1.4
%
0.07
104
1096
343
3328
1.03
0.22
1.2
1.2
—
—
—
0
0
56
608
0.92
0.22
1.1
1.1
—
—
—
0
0
115
1215
0.94
0.22
5.4
6.5
24.4
24.6
mmol/l
0.28
115
1209
5
40
1.25
0.22
1.2
2.4
—
—
—
0
0
23
200
1.15
0.22
1.2
1.4
—
—
—
0
0
40
441
0.91
0.22
1.9
2.0
—
—
—
0
0
10
124
0.81
0.21
1.4
1.6
—
111.5
—
0
17
118
1119
1.06
0.21
1.3
1.3
14.2
10.5
u/ml
0.14
15
126
5
42
1.19
0.21
2.6
1.9
2.2
2.5
ug/l
—
5
35
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
3.6
—
—
—
0
0
16
188
0.85
0.21
1.4
1.5
—
2356.9
—
0
28
57
616
0.92
0.21
1.2
1.3
1.2
1.4
nmol/l
0.78
48
500
8
101
0.79
0.21
1.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
73
780
0.93
0.20
2.2
2.7
—
—
—
0
0
789
7758
1.02
0.20
1.6
1.6
1.3
1.4
mmol/l
0.81
687
6842
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
37
407
0.91
0.20
4.6
3.0
18.1
26.9
mg/l
2.74
28
332
6
49
1.22
0.20
1.0
1.1
—
—
—
0
0
3193
31795
1.02
0.19
3.3
3.4
5.5
5.6
mmol/l
1.66
3047
30233
22
193
1.14
0.19
1.0
1.4
—
—
—
0
0
77
819
0.94
0.19
1.1
1.1
—
—
—
0
0
603
6146
0.98
0.19
1.3
1.3
—
—
—
0
0
11
90
1.22
0.19
2.5
2.0
—
—
—
0
0
18
207
0.87
0.19
1.1
1.1
1486.4
1522.2
miu/ml
0.04
18
207
33
364
0.91
0.19
1.4
1.4
—
—
—
0
0
108
1030
1.05
0.17
1.2
1.3
20.0
39.1
u/ml
1.35
11
102
31
281
1.10
0.17
1.1
1.1
—
—
—
0
0
111
1162
0.95
0.17
1.1
1.1
2.5
1.0
u/ml
0.68
43
433
7
62
1.13
0.17
2.0
1.9
—
—
—
0
0
22
247
0.89
0.17
1.9
2.9
—
—
—
0
0
307
2992
1.03
0.17
1.4
1.3
167.9
183.0
u/ml
0.11
288
2783
35
320
1.09
0.17
5.5
4.7
63.4
64.7
%
0.13
35
320
7
63
1.11
0.17
1.3
1.7
—
—
—
0
0
5
68
0.74
0.17
1.6
1.5
—
—
—
0
0
8
69
1.16
0.16
2.5
2.3
—
—
—
0
0
43
399
1.08
0.15
1.4
1.4
—
—
—
0
0
663
6530
1.02
0.15
2.6
2.5
—
—
—
0
0
6
80
0.75
0.15
2.7
2.8
—
—
—
0
0
20
178
1.12
0.15
1.4
1.5
134.5
134.2
nmol/l
0.01
20
178
25
226
1.11
0.15
3.7
2.7
—
—
—
0
0
359
3666
0.98
0.15
1.3
1.4
—
—
—
0
0
200
2059
0.97
0.15
7.3
7.1
0.5
0.8
mmol/l
0.30
153
1574
48
449
1.07
0.15
1.3
1.3
—
—
—
0
0
7
88
0.80
0.14
1.1
1.1
—
—
—
0
0
348
3411
1.02
0.14
2.3
2.1
366.7
373.2
nmol/l
0.32
336
3148
400
3927
1.02
0.14
2.4
2.5
5.5
4.8
e6/l
0.37
192
1978
12
103
1.17
0.13
1.2
1.3
—
—
—
0
0
44
412
1.07
0.13
5.0
6.7
10.7
11.1
mmol/l
0.40
37
376
32
346
0.92
0.13
2.4
2.7
1.2
1.3
e9/l
0.37
21
199
77
806
0.95
0.13
1.1
1.1
0.8
3.4
u/ml
6.54
27
327
24
263
0.91
0.13
1.2
1.5
—
—
—
0
0
24
263
0.91
0.13
1.2
1.5
—
—
—
0
0
24
263
0.91
0.13
1.2
1.5
—
—
—
0
0
24
263
0.91
0.13
1.2
1.5
—
—
—
0
0
23
209
1.10
0.13
1.1
1.1
8.1
9.1
u/ml
—
5
34
9
108
0.83
0.13
1.8
1.4
21.9
33.8
mmol/l
—
9
95
47
499
0.94
0.13
4.1
4.7
62.1
100.0
u/ml
0.32
15
164
44
413
1.07
0.13
5.0
6.7
105.3
105.8
mmol/l
0.28
37
377
208
2133
0.97
0.13
1.9
2.5
1.7
1.7
%
0.04
184
1897
106
1100
0.96
0.12
1.2
1.1
—
—
—
0
0
49
462
1.06
0.12
2.0
2.8
23.9
24.1
mmol/l
0.15
43
404
762
7708
0.99
0.12
3.1
3.8
7.4
7.4
ph
0.08
161
1439
190
1950
0.97
0.12
2.0
1.8
1.3
1.3
g/l
0.19
182
1837
180
1753
1.03
0.12
3.7
4.0
—
7.4
—
0
7
17
152
1.12
0.12
1.1
1.0
—
—
—
0
0
3370
33782
0.99
0.12
3.4
3.5
4.9
4.9
mmol/l
3.53
3249
32582
114
1102
1.04
0.12
2.3
1.9
—
—
—
0
0
95
986
0.96
0.12
8.0
9.1
—
—
—
0
0
94
975
0.96
0.11
1.1
1.1
—
—
—
0
0
94
975
0.96
0.11
1.1
1.1
—
—
—
0
0
200
2046
0.98
0.11
7.3
7.0
5.0
5.1
kpa
0.08
190
1971
200
2045
0.98
0.10
7.2
7.0
14.1
14.0
kpa
0.07
191
1967
15
167
0.90
0.10
2.3
2.4
7.5
7.8
%
0.08
15
162
16
144
1.11
0.10
1.1
1.1
—
—
—
0
0
107
1104
0.97
0.10
1.1
1.1
—
—
—
0
0
43
407
1.06
0.10
5.3
4.4
—
—
—
0
0
353
3585
0.98
0.10
1.3
1.4
—
—
—
0
0
3409
34023
1.01
0.09
3.5
3.7
3.0
3.0
mmol/l
0.53
3253
32595
18
164
1.10
0.09
3.3
2.6
10.7
10.9
%
0.06
18
164
22
238
0.92
0.09
1.1
1.1
—
—
—
0
0
26
242
1.07
0.09
1.2
1.2
—
—
—
0
0
248
2524
0.98
0.09
1.4
1.3
—
—
—
0
0
42
399
1.05
0.09
1.8
1.6
—
—
—
0
0
3421
34147
1.01
0.09
10.2
10.8
39.5
39.8
%
1.31
2832
29027
37
390
0.95
0.08
2.5
2.6
19.2
85.9
ug/min
2.98
23
254
12
134
0.90
0.08
2.0
1.9
—
—
—
0
0
162
1586
1.02
0.08
1.7
1.7
—
—
—
0
0
145
1418
1.02
0.08
2.2
2.6
71.2
72.6
e9/l
0.15
98
1007
5
61
0.82
0.08
1.0
1.5
20.8
44.7
%
—
5
52
573
5676
1.01
0.08
1.6
1.5
20582943.7
34923260.4
pmol/l
0.29
515
5054
13
117
1.11
0.08
1.2
1.1
5.4
5.1
nmol/l
0.12
13
109
3359
33648
0.99
0.08
3.3
3.4
1.5
1.6
mmol/l
4.21
3226
32398
12
133
0.90
0.07
1.1
1.1
—
—
—
0
0
6
74
0.81
0.07
1.3
1.8
—
—
—
0
0
26
276
0.94
0.07
1.1
1.2
—
—
—
0
0
25
235
1.06
0.07
1.8
2.4
—
—
—
0
0
161
1640
0.98
0.07
1.4
1.3
—
—
—
0
0
43
412
1.04
0.07
1.4
1.6
—
—
—
0
0
7
81
0.86
0.07
1.7
1.6
—
—
—
0
0
7
80
0.87
0.07
1.0
1.1
—
—
—
0
0
14
153
0.91
0.07
1.0
1.1
0.5
1.5
u/ml
—
6
84
9
100
0.90
0.06
1.6
1.2
—
—
—
0
0
9
103
0.87
0.06
5.3
4.8
—
—
—
0
0
290
2934
0.99
0.06
4.1
5.5
1.0
1.0
mmol/l
0.29
279
2780
109
1067
1.02
0.06
8.3
6.4
24.4
24.3
mmol/l
0.04
98
996
177
1743
1.02
0.06
7.6
7.7
97.1
96.3
%
1.77
170
1679
10
111
0.90
0.06
2.8
2.9
—
—
—
0
0
17
182
0.93
0.05
1.2
1.1
—
—
—
0
0
24
253
0.95
0.05
1.5
1.8
39.0
51.9
%
0.82
16
160
34
326
1.04
0.05
1.4
1.5
0.9
1.0
g/l
0.97
34
326
112
1141
0.98
0.05
2.2
2.7
5.0
5.1
kpa
0.56
99
1071
17
159
1.07
0.05
2.3
2.0
26.2
30.2
umol/l
2.18
17
151
33
343
0.96
0.04
1.1
1.0
—
—
—
0
0
18
191
0.94
0.04
1.3
1.5
8618.3
19883.1
e6/l
0.47
12
138
161
1631
0.99
0.04
1.4
1.3
—
—
—
0
0
454
4513
1.01
0.04
1.2
1.2
—
—
—
0
0
103
1046
0.98
0.04
1.1
1.1
2.7
4.9
u/ml
1.96
53
538
39
402
0.97
0.04
1.1
1.1
—
—
—
0
0
1049
10523
1.00
0.03
5.3
6.2
—
—
—
0
0
14
131
1.07
0.03
2.2
2.2
—
—
—
0
0
167
1687
0.99
0.03
3.7
4.1
1.4
1.8
mmol/l
0.88
136
1378
221
2194
1.01
0.02
3.1
3.5
21.8
27.4
ug/l
0.10
154
1537
225
2266
0.99
0.02
2.9
3.3
—
—
—
0
0
74
729
1.02
0.02
3.6
3.6
59.0
56.6
%
1.16
74
729
1136
11384
1.00
0.02
4.5
5.0
1.2
1.2
mmol/l
0.68
1054
10504
53
540
0.98
0.02
1.6
1.7
9929.7
7482.3
e6/l
0.15
43
393
35
341
1.03
0.02
1.1
1.2
—
—
—
0
0
19
198
0.96
0.02
1.1
1.1
—
—
—
0
0
111
1121
0.99
0.02
2.2
2.7
7.4
7.4
ph
1.18
17
138
2879
28770
1.00
0.02
3.9
4.0
37.1
37.4
mmol/mol
0.83
2749
27544
28
288
0.97
0.02
2.0
2.2
76.5
75.1
%
0.37
28
282
180
1811
0.99
0.01
1.2
1.3
2.0
1.0
u/ml
0.32
14
154
14
133
1.05
0.01
1.0
1.2
—
—
—
0
0
42
428
0.98
0.01
2.1
1.3
—
—
—
0
0
288
2870
1.00
0.01
2.3
2.4
37.6
36.4
u/l
0.05
254
2462
80
807
0.99
0.01
1.8
1.4
209.4
5236.4
e6/l
0.57
63
654
80
807
0.99
0.01
1.7
1.3
81.1
31.3
e6/l
0.32
62
623
12
114
1.05
0.00
1.0
1.2
—
—
—
0
0
24
246
0.98
0.00
1.3
1.8
—
—
—
0
0
120
1206
0.99
0.00
1.9
1.9
5.7
6.2
ug/l
0.09
112
1053
15
152
0.99
0.00
1.0
2.5
—
—
—
0
0
21
208
1.01
0.00
1.3
3.0
—
—
—
0
0
27
272
0.99
0.00
6.1
7.4
—
—
—
0
0
28
282
0.99
0.00
2.0
2.2
16.3
13.5
%
0.67
14
154
31
312
0.99
0.00
2.1
2.5
—
—
—
0
0
203
2028
1.00
0.00
1.4
1.4
—
—
—
0
0
99
985
1.01
0.00
1.1
1.1
0.9
0.9
u/ml
0.03
39
401
20
201
1.00
0.00
1.7
1.5
—
—
—
0
0
49
491
1.00
0.00
1.1
1.1
60.3
762.9
iu/ml
0.56
18
117
68
679
1.00
0.00
7.0
4.2
—
—
—
0
0
36
364
0.99
0.00
1.1
1.0
1.6
0.5
u/ml
0.42
12
79
13
134
0.97
0.00
1.4
2.3
237.1
153.7
e6/l
—
7
75
37
367
1.01
0.00
1.1
1.0
0.4
0.4
u/ml
—
10
97
139
1393
1.00
0.00
1.9
1.4
0.5
0.5
nmol/l
0.06
113
1089
74
743
1.00
0.00
1.4
1.5
—
6.9
—
0
15
18
177
1.02
0.00
1.2
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
5
59
0.85
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
8
88
0.91
0.00
1.5
1.5
—
—
—
0
0
27
270
1.00
0.00
1.5
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
29.1
—
0
6
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
12
120
1.00
0.00
1.3
1.1
—
3.2
iu/ml
—
0
9
26
260
1.00
0.00
1.3
1.3
—
68.0
—
0
21
5
58
0.86
0.00
2.6
1.9
—
—
—
0
0
380
3800
1.00
0.00
1.9
1.7
1224.0
1195.2
nmol/l
0.27
317
3017
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
86
0.93
0.00
1.6
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
131.7
—
0
5
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
0.6
—
0
5
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint O15_MULTIP_GEST and mortality.

Females

Parameter HR [95% CI] p-value
O15_MULTIP_GEST 0.55 [0.44, 0.69] < 0.001
Birth year 0.99 [0.98, 1.0] 0.025

During the follow-up period (1.1.1998 — 31.12.2019), 101 out of 19121 females with O15_MULTIP_GEST died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_MULTIP_GEST.

N-year risk Females Males
1 0.041% No data
5 0.293% No data
10 0.648% No data
15 1.275% No data
20 2.25% No data

Relationships between endpoints

Index endpoint: O15_MULTIP_GEST – Multiple gestation

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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