This is a non-core endpoint: only basic statistics are computed.
See its core counterpart CD2_INSITU_SKIN_EAR_EXALLC for full statistics.
Carcinoma in situ of skin of ear and external auricular canal
CD2_INSITU_SKIN_EAR
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
451 |
4. Check minimum number of eventsNone |
451 |
5. Include endpointsNone |
451 |
6. Filter based on genotype QC (FinnGen only) |
451 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D04
- Name in latin
- Carcinoma in situ cutis auriculae
Similar endpoints
↥List of similar endpoints to
Carcinoma in situ of skin of ear and external auricular canal
based on the number of shared cases.
Similar with more cases:
- Carcinoma in situ of skin of ear and external auricular canal
- In situ neoplasms
- In situ neoplasms
- Neoplasms
- Any operation in hilmo
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 451 | 55 | 396 |
| Unadjusted period prevalence (%) | 0.16 | 0.02 | 0.17 |
| Median age at first event (years) | 78.48 | 74.91 | 78.98 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 382
- Matched controls
- 3819
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D04.2
ICD-10 Finland
Carcinoma in situ: Skin of ear and external auricular canal
+∞
323.0
382
*
L57.0
ICD-10 Finland
Actinic keratosis
30.5
176.8
280
315
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
18.7
122.7
215
245
TQW99
NOMESCO Finland
Other minor procedure on skin
22.2
98.4
151
109
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
12.6
91.5
191
281
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
30.5
86.8
118
55
DAB00
NOMESCO Finland
Excision of lesion of auricle
48.5
69.6
84
22
R23.8
ICD-10 Finland
Other and unspecified skin changes
8.0
62.1
168
341
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
9.2
59.9
142
231
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
24.3
59.7
86
45
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
10.7
57.1
120
156
C44.22
ICD-10 Finland
Spinocellular carcinoma of the skin of the outer ear and the outer ear canal
61.3
53.7
62
12
D06BB10
ATC
imiquimod; topical
14.2
51.3
91
82
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
23.2
50.8
74
39
ZQZ00
NOMESCO Finland
Treatment of several skin areas
47.0
43.8
53
13
S18
ICPC
Laceration/cut
4.6
42.8
261
1214
D04.4
ICD-10 Finland
Carcinoma in situ: Skin of scalp and neck
46.0
42.8
52
13
DAB10
NOMESCO Finland
Partial excision of auricle
34.7
41.8
54
18
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
24.1
39.2
56
27
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
25.5
39.2
55
25
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
42.0
38.9
48
13
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
10.9
38.0
76
85
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
12.5
37.8
70
67
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
11.7
37.5
72
74
ZXC50
NOMESCO Finland
Cryotherapy
10.4
37.0
76
89
ZXC20
NOMESCO Finland
Use of chemical agents
14.0
36.5
64
54
Z2221
NOMESCO Finland
Medical doctor
4.2
34.8
176
645
ZXC15
NOMESCO Finland
Use of photodynamic technique
18.6
33.5
52
32
ZZR00
NOMESCO Finland
Flap of skin
11.9
32.3
61
60
C44.21
ICD-10 Finland
Basocellular carcinoma of the skin of the outer ear and the outer ear canal
14.8
31.3
53
41
C44.42
ICD-10 Finland
Spinocellular carcinoma of the skin of the scalp and neck
35.9
28.3
36
11
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
6.5
27.8
78
146
127
Kela drug reimbursment
Transplant complication
34.7
25.1
32
10
ZXD10
NOMESCO Finland
Scheduled procedure
3.1
24.7
206
1039
L82
ICD-10 Finland
Seborrhoeic keratosis
3.9
23.8
113
368
Z3231
NOMESCO Finland
Registered nurse
3.2
23.7
167
742
D23.2
ICD-10 Finland
Benign neoplasm: Skin of ear and external auricular canal
17.1
22.8
36
23
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
9.6
22.6
47
55
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
11.1
22.5
43
43
J01DB01
ATC
cefalexin; oral
3.6
22.1
323
2304
WX002
NOMESCO Finland
Sedation and analgesia
3.5
21.9
123
453
D04.7
ICD-10 Finland
Carcinoma in situ: Skin of lower limb, including hip
28.4
21.7
29
11
Z94.0
ICD-10 Finland
Kidney transplant status
28.4
21.7
29
11
ZXE00
NOMESCO Finland
One hour or less
2.9
21.4
194
999
A98
ICPC
Health maint/preventive medicine
4.0
20.9
342
2592
8070/3-C44.2
ICD-O-3
Squamous cell carcinoma, NOS, of external ear
32.1
20.8
27
9
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
51.0
20.4
24
5
ZXA00
NOMESCO Finland
Right side
3.0
20.3
161
754
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
9.9
20.2
41
46
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
13.7
19.8
34
27
WX110
NOMESCO Finland
Local anesthesy
2.7
19.5
252
1579
L04AA06
ATC
mycophenolic acid; systemic
21.5
19.4
28
14
C44.62
ICD-10 Finland
Spinocellular carcinoma of the skin of the upper extremity including the shoulder
58.1
19.1
22
*
SPAT1153
SPAT
Removal of sutures
2.8
19.0
176
900
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.6
18.6
227
1360
S21
ICPC
Skin texture symptom/complaint
3.8
18.3
87
278
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
9.3
18.2
38
45
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
30.5
17.6
23
8
ZXE10
NOMESCO Finland
More than one and less than three hours
2.6
17.4
178
951
L04AD01
ATC
ciclosporin; systemic
17.0
17.3
27
17
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
4.0
17.2
75
221
XQ848
NOMESCO Finland
Dermatological photography
7.6
15.0
35
50
C44.20
ICD-10 Finland
Malignant tumor of the skin of the outer ear and of the outer ear canal without histology
26.3
14.8
20
8
E0000UV
ATC
NA
2.5
14.7
157
838
ZXA05
NOMESCO Finland
Left side
2.5
14.5
143
728
TDA10
NOMESCO Finland
Needle biopsy of auricle or external auditory canal
23.3
14.4
20
9
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
5.0
14.2
47
105
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
8.7
14.1
30
37
D04.8
ICD-10 Finland
Carcinoma in situ: Skin of other sites
144.9
13.5
14
*
S29
ICPC
Skin symptom/complaint other
2.8
13.5
96
403
A12AA04
ATC
calcium carbonate; oral
9.6
13.5
27
30
N02BE01
ATC
paracetamol; systemic, rectal
2.8
13.3
328
2612
8070/3-C44.3
ICD-O-3
Squamous cell carcinoma, NOS, of skin of other and unspecified parts of face
15.8
13.2
21
14
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
6.3
13.2
35
60
R4110
NOMESCO Finland
Physiotherapy
2.5
13.2
126
626
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
5.1
12.9
41
88
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.6
12.8
116
557
DHB00
NOMESCO Finland
Excision of lesion of external nose
13.8
12.6
21
16
Z3226
NOMESCO Finland
Physiotherapist
2.7
12.6
96
418
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
7.0
12.3
30
46
Z3229
NOMESCO Finland
Other healthcare associate professional
3.3
11.9
62
209
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
31.1
11.7
15
5
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
10.8
120
632
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
61.7
10.7
12
*
A11CC03
ATC
alfacalcidol; systemic
5.9
10.7
29
52
Z2446
NOMESCO Finland
Social worker
4.3
10.6
39
98
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.7
10.3
75
314
D06BX02
ATC
ingenol mebutate; topical
7.2
10.3
24
35
TK800
NOMESCO Finland
Hemodialysis
7.2
10.3
24
35
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.9
10.0
62
236
QCA25
NOMESCO Finland
Destruction of lesion of skin of upper limb
12.6
9.9
17
14
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
9.9
9.9
19
20
QDA25
NOMESCO Finland
Destruction of lesion of skin of lower limb
56.4
9.7
11
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.4
9.7
89
424
ZX120
NOMESCO Finland
Intravenous
3.0
9.7
56
204
C44.52
ICD-10 Finland
Spinocellular carcinoma of the skin on the torso
15.5
9.6
15
10
TQW80
NOMESCO Finland
Local dermatologic skincare
6.5
9.5
24
39
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
6.1
9.5
25
43
Z49.1
ICD-10 Finland
Extracorporeal dialysis
9.0
9.4
19
22
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
11.1
9.4
17
16
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
5.2
9.3
28
57
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.4
9.1
44
141
8070/3-C44.4
ICD-O-3
Squamous cell carcinoma, NOS, of skin of scalp and neck
37.6
9.1
11
*
QAB10
NOMESCO Finland
Major dressing of wound of skin of head or neck
12.9
8.9
15
12
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.0
8.8
34
90
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.7
8.8
29
66
H81
ICPC
Excessive ear wax
2.2
8.7
101
537
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
4.9
8.6
27
58
B01AB05
ATC
enoxaparin; parenteral
2.0
8.5
130
773
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
8.5
100
534
WXQ99
NOMESCO Finland
Other light therapy
92.0
8.4
9
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
8.3
156
1003
KA1AE
NOMESCO Finland
Kidney ultrasound examination
5.6
8.3
23
43
ZZA00
NOMESCO Finland
Split skin graft
4.3
8.3
30
75
QBA50
NOMESCO Finland
Cryotherapy of skin of trunk
14.9
8.3
13
9
I10
ICD-10 Finland
Essential (primary) hypertension
1.9
8.2
269
2104
N02AJ06
ATC
codeine and paracetamol; systemic
2.0
8.2
125
741
SAA01
NOMESCO Finland
Simple examination of mouth
1.9
8.2
201
1420
D04.9
ICD-10 Finland
Carcinoma in situ: Skin, unspecified
17.6
8.1
12
7
Z49.0
ICD-10 Finland
Preparatory care for dialysis
8.0
8.0
17
22
C07AB07
ATC
bisoprolol; oral
1.9
7.9
232
1734
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
7.2
7.9
18
26
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.3
7.9
38
122
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.3
7.8
76
370
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.9
7.8
160
1058
L17
ICPC
Foot/toe symptom/complaint
2.1
7.8
106
601
TQW40
NOMESCO Finland
Remowal of suture of skin
3.6
7.7
34
102
L03
ICPC
Low back symptom/complaint
2.2
7.6
87
457
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.9
7.6
156
1029
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.8
7.6
182
1264
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.9
7.6
154
1011
J01CA04
ATC
amoxicillin; systemic
1.9
7.5
266
2100
ZXE20
NOMESCO Finland
More than three and less than five hours
2.3
7.5
74
364
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
3.0
7.5
42
149
C44.50
ICD-10 Finland
Malignant tumor of the skin on the torso without histology
13.7
7.4
12
9
H02AB04
ATC
methylprednisolone; systemic
2.4
7.4
67
316
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
2.1
7.2
86
458
XF404
NOMESCO Finland
Ambulatory ECG
2.5
7.2
55
237
TQW40
SPAT
NA
5.8
7.2
19
34
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.4
7.1
62
284
C44.81
ICD-10 Finland
Overall basocellular carcinoma of the skin
12.3
7.1
12
10
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
7.1
134
851
8090/3-C44.2
ICD-O-3
Basal cell carcinoma, NOS, of external ear
7.2
7.1
16
23
KMAK
NOMESCO Finland
NA
1.8
7.0
145
952
N18.0
ICD-10 Finland
End-stage renal disease
6.0
7.0
18
31
ZXD05
NOMESCO Finland
Urgent procedure
1.9
7.0
135
867
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
4.2
6.9
25
63
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.9
6.9
127
797
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
6.3
6.8
17
28
C44.71
ICD-10 Finland
Basocellular carcinoma of the skin of the lower extremity including the hip
9.6
6.8
13
14
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
4.9
6.8
21
45
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
3.8
6.7
27
75
L04AA01
ATC
[U] ciclosporin; systemic
8.0
6.7
14
18
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.0
6.7
104
614
S97
ICPC
Chronic ulcer skin
2.9
6.6
38
138
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.8
6.6
158
1081
H02.1
ICD-10 Finland
Ectropion of eyelid
5.5
6.5
18
34
S15
ICPC
Foreign body in skin
3.0
6.5
36
126
SAA02
NOMESCO Finland
Basic examination of mouth
1.8
6.4
169
1188
M79.6
ICD-10 Finland
Pain in limb
1.8
6.4
122
775
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
6.4
107
649
Z02.4
ICD-10 Finland
Examination for driving licence
1.8
6.4
137
903
D07AB08
ATC
desonide; topical
2.6
6.4
47
198
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
6.3
151
1030
CBN30
NOMESCO Finland
Shortening of canthal ligament
11.3
6.3
11
10
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.9
6.3
118
742
WXQ41
NOMESCO Finland
Photodynamic therapy of head and neck
18.4
6.3
9
5
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
18.4
6.3
9
5
D07AC01
ATC
betamethasone; topical
1.8
6.3
132
864
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
7.2
6.3
14
20
C44.2
ICD-10 Finland
Malignant neoplasm: Skin of ear and external auricular canal
+∞
6.3
6
*
207
Kela drug reimbursment
Chronic arrhythmias
1.9
6.2
95
557
WX320
NOMESCO Finland
Spinalanesthesy
1.9
6.2
96
565
N18.8
ICD-10 Finland
Other chronic renal failure
3.5
6.2
27
81
Z71.8
ICD-10 Finland
Other specified counselling
2.0
6.1
77
420
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: CD2_INSITU_SKIN_EAR – Carcinoma in situ of skin of ear and external auricular canal
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).