Divergent concomitant strabismus

H7_DIVERGSTRAB

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H50.1
  • Hospital discharge: ICD-9 3781
  • Hospital discharge: ICD-8 37301
  • Cause of death: ICD-10 H50.1
  • Cause of death: ICD-9 3781
  • Cause of death: ICD-8 37301

2 out of 7 registries used, show all original rules.

3261

4. Check minimum number of events

None

3261

5. Include endpoints

None

3261

6. Filter based on genotype QC (FinnGen only)

3161

Control definitions (FinnGen only)

Control exclude
H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H50
Name in latin
Strabismus divergens concomitans

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 30557 17266 13194
Only index persons 27598 15794 11804
Unadjusted period prevalence (%)
Whole population 0.44 0.49 0.37
Only index persons 0.53 0.58 0.45
Median age at first event (years)
Whole population 13.93 14.80 12.62
Only index persons 13.95 14.85 12.74

-FinnGen-

Key figures

All Female Male
Number of individuals 3161 2047 1114
Unadjusted period prevalence (%) 0.65 0.73 0.51
Median age at first event (years) 20.98 18.07 26.33

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3261
Matched controls
32610
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
2937.6
307.7
521
*
H50.31
ICD-10 Finland
Intermittent exotropia
1843.5
307.7
464
*
H50.52
ICD-10 Finland
Exophoria
88.4
307.7
268
33
3503
FHL
Single muscle retroposition
+∞
307.7
347
*
37301
ICD-8 Finland
Strabismus, Concomitans divergens
+∞
307.7
1664
*
H50.1
ICD-10 Finland
Divergent concomitant strabismus
6259.5
307.7
1240
*
3781B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS DIVERGENS ALTERNANS]
+∞
304.0
287
*
3781A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS CONCOMITANS DIVERGENS]
+∞
262.1
248
*
CEC00
NOMESCO Finland
Recession of extraocular muscle
2038.3
210.6
202
*
3507
FHL
Retroposition and resection
1971.2
204.2
196
*
H53.0
ICD-10 Finland
Amblyopia ex anopsia
26.6
192.6
133
52
37303
ICD-8 Finland
Strabismus, Heterophoria (exophoria, esophroria, hypophoria)
+∞
162.9
155
*
H50.2
ICD-10 Finland
Vertical strabismus
237.1
154.6
158
7
37300
ICD-8 Finland
Strabismus, Concomitans convergens
+∞
149.1
142
*
H53.2
ICD-10 Finland
Diplopia
7.2
125.1
190
276
H50.0
ICD-10 Finland
Convergent concomitant strabismus
620.9
122.1
120
*
CEC30
NOMESCO Finland
Resection of extraocular muscle
+∞
118.5
113
*
3505
FHL
Single muscle resection
+∞
114.2
109
*
H50.51
ICD-10 Finland
Esophoria
48.7
82.3
48
10
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
81.6
78
*
H52.0
ICD-10 Finland
Hypermetropia
9.3
77.4
94
104
3782B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Intermittent heterotropia[STRABISMUS DIVERGENS INTERMITTENS]
+∞
77.4
74
*
H50.30
ICD-10 Finland
Intermittent esotropy
734.6
73.5
72
*
CEW99
NOMESCO Finland
Other operation on extraocular muscle
+∞
69.0
66
*
WX140
NOMESCO Finland
Parabulbar anesthesy
4.0
66.4
197
517
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
15.2
64.9
57
38
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.7
62.0
377
1523
H52.1
ICD-10 Finland
Myopia
5.5
60.6
119
223
3504
FHL
Retroposition of two muscles
+∞
59.6
57
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.2
57.6
613
3164
H50.9
ICD-10 Finland
Strabismus, unspecified
81.7
57.1
64
8
3784B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Heterophoria[EXOPHORIA]
+∞
55.4
53
*
37720
ICD-8 Finland
Other diseases of retina and optic nerve, Amblyopia
193.3
55.1
57
*
H52.2
ICD-10 Finland
Astigmatism
8.0
53.7
73
93
XCK00
NOMESCO Finland
Perimetry
3.1
49.0
215
726
H51.1
ICD-10 Finland
Convergence insufficiency and excess
464.3
46.4
46
*
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
15.2
40.8
36
24
CEC20
NOMESCO Finland
Recession and advancement of extraocular muscle
+∞
40.7
39
*
CEC50
NOMESCO Finland
Advancement of extraocular muscle
+∞
39.7
38
*
37302
ICD-8 Finland
Strabismus, Concomitans sursum sive deorsum vergens
+∞
38.6
37
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.7
38.3
946
6311
3781X
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS DIVERGENS ALIUS]
+∞
36.5
35
*
H27.0
ICD-10 Finland
Aphakia
14.0
34.8
32
23
H50.8
ICD-10 Finland
Other specified strabismus
96.1
34.8
38
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.7
33.0
184
707
3508
FHL
Transposition or anteposition
+∞
32.3
31
*
37001
ICD-8 Finland
Refractive errors, Hypermetropia. Hyperopia
+∞
32.3
31
*
F95
ICPC
Strabismus
111.1
30.7
33
*
3780A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONCOMITANS CONVERGENS]
+∞
30.2
29
*
CEC40
NOMESCO Finland
Resection and advancement of extraocular muscle
+∞
26.1
25
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
26.1
1188
8982
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.0
25.3
281
1451
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
8.9
25.1
31
35
3680A
ICD-9 Finland
Visual disturbances, Amblyopia ex anopsia
+∞
25.0
24
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.1
24.1
248
1245
3783A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Other and unspecified heterotropia
+∞
24.0
23
*
H50.4
ICD-10 Finland
Other and unspecified heterotropia
+∞
24.0
23
*
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
241.7
23.7
24
*
183
Kela drug reimbursment
Lamotrigin and topiramate
5.3
23.0
46
88
37002
ICD-8 Finland
Refractive errors, Myopia
+∞
22.9
22
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.9
22.6
300
1646
N03AG01
ATC
valproic acid; systemic, rectal
2.2
22.1
203
975
ZXA00
NOMESCO Finland
Right side
1.6
22.0
706
4919
N03AX09
ATC
lamotrigine; oral
2.2
21.9
187
872
ZXA05
NOMESCO Finland
Left side
1.6
21.1
645
4438
H50.3
ICD-10 Finland
Intermittent heterotropia
+∞
19.8
19
*
3519
FHL
Other measure in this category
+∞
18.8
18
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
18.3
208
1081
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.9
18.2
247
1362
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.6
18.2
105
411
N05AH02
ATC
clozapine; systemic
3.1
18.1
77
256
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.5
18.0
594
4142
3780B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONVERGENS ALTERNANS]
+∞
17.7
17
*
N05AH03
ATC
olanzapine; systemic
2.0
17.6
210
1110
H53.3
ICD-10 Finland
Other disorders of binocular vision
6.4
17.5
29
46
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
180.9
17.5
18
*
Z3231
NOMESCO Finland
Registered nurse
1.5
17.2
758
5600
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
63.7
16.7
19
*
H51.8
ICD-10 Finland
Other specified disorders of binocular movement
+∞
16.7
16
*
37872
ICD-8 Finland
Other diseases of eye, Aphakia artefacta, acquisita
40.3
16.3
20
5
Z3229
NOMESCO Finland
Other healthcare associate professional
1.9
16.2
227
1266
H53.1
ICD-10 Finland
Subjective visual disturbances
1.9
15.9
193
1026
H25.1
ICD-10 Finland
Senile nuclear cataract
1.5
15.8
501
3455
ZXA10
NOMESCO Finland
Bilateral
1.5
15.4
470
3213
F20.9
ICD-10 Finland
Schizophrenia, unspecified
2.7
15.3
80
298
N05AH04
ATC
quetiapine; oral
1.5
15.3
538
3792
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.0
15.3
167
856
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
2.9
15.0
69
240
N05BA09
ATC
clobazam; oral
5.0
15.0
32
65
N04AA02
ATC
biperiden; systemic
3.0
14.9
66
225
3793A
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[APHAKIA]
31.8
14.8
19
6
H26.4
ICD-10 Finland
After-cataract
1.9
14.5
195
1072
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
14.4
416
2808
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
14.4
573
4135
N03AF02
ATC
oxcarbazepine; oral
2.4
14.3
101
436
H54.5
ICD-10 Finland
Severe visual impairment, monocular
6.0
13.8
24
40
WX704
NOMESCO Finland
Intubation
1.8
13.8
225
1313
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
13.7
968
7709
N05AX12
ATC
aripiprazole; systemic
2.0
13.7
140
702
S01ED01
ATC
timolol; ophthalmic
2.5
13.6
82
329
N03AX14
ATC
levetiracetam; systemic
2.5
13.4
81
325
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
4.0
13.3
37
93
ZXD20
NOMESCO Finland
Day surgery
1.6
13.2
363
2421
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.7
13.0
233
1395
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
22.6
12.9
18
8
G40.10
ICD-10 Finland
Simple partial seizures
4.7
12.8
29
62
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
12.8
327
2145
WX002
NOMESCO Finland
Sedation and analgesia
1.5
12.8
491
3514
N06AX11
ATC
mirtazapine; oral
1.3
12.6
947
7595
R62.0
ICD-10 Finland
Delayed milestone
5.2
12.5
25
48
F83
ICD-10 Finland
Mixed specific developmental disorders
5.6
12.4
23
41
H26.02
ICD-10 Finland
Presenil cataract
2.5
12.0
76
312
37405
ICD-8 Finland
Cataract, Traumatica
21.4
12.0
17
8
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
10.5
11.7
22
21
AA1AD
NOMESCO Finland
CT of head and brain
1.4
11.7
622
4715
N06AB06
ATC
sertraline; oral
1.5
11.5
335
2261
K59.09
ICD-10 Finland
Constipation, unspecified
1.8
11.5
157
868
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
11.5
298
1960
114
Kela drug reimbursment
Glaucoma
1.8
11.5
173
986
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.7
11.5
223
1367
P85
ICPC
Mental retardation
13.6
11.4
19
14
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
120.4
11.4
12
*
WX142
NOMESCO Finland
Sub-tenon anesthesy
4.8
11.4
25
52
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.1
11.4
113
561
N03AF01
ATC
carbamazepine; oral, rectal
1.9
11.3
130
681
N05AA02
ATC
levomepromazine; systemic
2.0
11.1
115
579
A46
ICD-10 Finland
Erysipelas
1.5
11.1
330
2237
N03AX12
ATC
[U] gabapentin; oral
1.5
11.0
426
3048
H54.7
ICD-10 Finland
Unspecified visual loss
4.8
10.9
24
50
N06AA09
ATC
amitriptyline; systemic
1.6
10.8
233
1466
N05BA01
ATC
diazepam; systemic, rectal
1.5
10.8
341
2342
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
2.9
10.6
48
166
N05CF01
ATC
zopiclone; oral
1.3
10.6
813
6510
SPAT1101
SPAT
Orthostatic test
2.2
10.6
87
401
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
4.1
10.6
28
68
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
10.5
689
5390
N03AE01
ATC
clonazepam; systemic
1.8
10.5
154
872
3506
FHL
Resection of two muscles
+∞
10.4
10
*
37000
ICD-8 Finland
Refractive errors, Astigmatismus
+∞
10.4
10
*
3510
FHL
Cardiac surgery on three or more muscles
+∞
10.4
10
*
3501
FHL
Myotomy or tenotomy
+∞
10.4
10
*
37003
ICD-8 Finland
Refractive errors, Anisometropia
+∞
10.4
10
*
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
12.1
10.3
18
15
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.5
10.3
329
2265
G47.3
ICD-10 Finland
Sleep apnoea
1.4
10.3
586
4486
H54.4
ICD-10 Finland
Blindness, monocular
10.6
10.3
19
18
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.5
10.2
281
1873
N05AX08
ATC
risperidone; systemic
1.7
10.2
202
1245
F20.39
ICD-10 Finland
Undifferentiated schizophrenia UNS
4.2
10.1
26
62
XKC03
NOMESCO Finland
Water cystometry
2.3
10.1
73
320
N03AX11
ATC
topiramate; oral
2.2
10.0
80
365
WX702
NOMESCO Finland
Supraglottic ventilation device
1.8
10.0
156
899
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
4.0
10.0
28
71
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.6
9.8
234
1512
34301
ICD-8 Finland
Cerebral spastic infantile paralysis, Diplegia spastica
55.2
9.6
11
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
9.6
1008
8405
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.6
9.6
252
1662
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
4.3
9.6
24
56
XA800
NOMESCO Finland
Neuropsychological investigation
1.9
9.6
119
640
S01EX03, ,
ATC
3.0
9.6
41
138
Q12.0
ICD-10 Finland
Congenital cataract
15.1
9.5
15
10
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.4
9.5
376
2700
WX400
NOMESCO Finland
Inhalation anesthesy
1.9
9.5
119
642
3431A
ICD-9 Finland
Infantile cerebral palsy, Hemiplegic
100.3
9.4
10
*
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
100.3
9.4
10
*
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
9.4
785
6351
H52.4
ICD-10 Finland
Presbyopia
2.2
9.3
75
344
N06AX16
ATC
venlafaxine; oral
1.4
9.3
415
3046
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.1
9.2
81
385
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.6
9.1
216
1391
S18
ICPC
Laceration/cut
1.3
9.0
1164
9939
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
4.1
9.0
24
59
WX725
NOMESCO Finland
Noninvasive ventilation
1.8
9.0
138
794
N06AB04
ATC
citalopram; systemic
1.3
8.8
558
4332
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
3.6
8.8
28
78
SPAT1240
SPAT
Therapeutic discussion
1.5
8.8
313
2201
L28
ICPC
Limited function/disability (L)
1.4
8.8
380
2773
XCK10
NOMESCO Finland
Photography of fundus of eye
1.6
8.7
213
1382
N05AD01
ATC
haloperidol; systemic
2.2
8.7
73
341
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.6
8.7
224
1473
H47.2
ICD-10 Finland
Optic atrophy
6.6
8.6
21
32
H05.2
ICD-10 Finland
Exophthalmic conditions
11.6
8.6
15
13
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
2.3
8.5
60
260
S01CA03
ATC
hydrocortisone and antiinfectives; ophthalmic
3.1
8.5
34
110
E66.8
ICD-10 Finland
Other obesity
1.7
8.5
162
989
SPAT1301
SPAT
No procedures
1.3
8.4
771
6299
M41.9
ICD-10 Finland
Scoliosis, unspecified
2.8
8.4
39
138
R06.0
ICD-10 Finland
Dyspnoea
1.3
8.2
644
5154
87011
ICD-8 Finland
Open wound of eye and orbit, Perforans oculi, Complicata
14.5
8.2
13
9
R02
ICPC
Shortness of breath/dyspnoea
1.5
8.2
298
2106
T82
ICPC
Obesity
1.8
8.1
117
660
H13
ICPC
Plugged feeling ear
1.4
8.1
426
3209
-1, ,
NOMESCO Finland
1.3
8.1
959
8082
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
2.2
8.1
66
305
37404
ICD-8 Finland
Cataract, Secundaria
33.4
8.1
10
*
CGD10
NOMESCO Finland
Laser keratoplasty for error of refraction
11.7
8.1
14
12
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
6.8
8.1
19
28
Z2445
NOMESCO Finland
Psychologist
1.8
8.1
113
633
G04BD08
ATC
solifenacin; oral
1.7
8.0
133
782
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.6
8.0
190
1225
ZXY60
NOMESCO Finland
2-person team, nurses
3.9
8.0
23
60
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
7.9
546
4288
H57.1
ICD-10 Finland
Ocular pain
1.8
7.9
104
572
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.6
7.8
198
1297
N05AF05
ATC
zuclopenthixol; systemic
3.2
7.8
30
95
R03AC02
ATC
salbutamol; inhalant
1.2
7.8
1599
14303
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.7
7.8
143
866
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
7.8
615
4924
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
2.2
7.7
61
279
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.3
7.6
494
3843
A06AD11
ATC
lactulose; oral
1.4
7.6
299
2143
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
2.4
7.6
48
199
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
3.5
7.4
24
68
H53.9
ICD-10 Finland
Visual disturbance, unspecified
1.9
7.4
88
468
S01ED51
ATC
timolol, combinations; ophthalmic
1.7
7.4
144
886
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
3.6
7.3
23
64
H50.5
ICD-10 Finland
Heterophoria
+∞
7.3
7
*
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
+∞
7.3
7
*
H50.6
ICD-10 Finland
Mechanical strabismus
+∞
7.3
7
*
UKC02
NOMESCO Finland
Cystoscopy
1.4
7.3
303
2196
R51.80
ICD-10 Finland
Headache
1.3
7.3
437
3363
N03AX16
ATC
[U] pregabalin
1.3
7.3
582
4665
XKD00
NOMESCO Finland
Uroflowmetry
1.5
7.2
264
1866
H40.3
ICD-10 Finland
Glaucoma secondary to eye trauma
15.8
7.2
11
7
A10BA02
ATC
metformin; oral
1.3
7.2
622
5033
G04BD12
ATC
mirabegron; oral
1.5
7.2
234
1618
N88
ICPC
Epilepsy
3.7
7.2
22
60
188
Kela drug reimbursment
Psychosis requiring demanding treatment
2.7
7.2
36
133
SPAT1139
SPAT
Nutrition survey
2.0
7.2
76
389
3430A
ICD-9 Finland
Infantile cerebral palsy, Diplegic
30.1
7.1
9
*
P72
ICPC
Schizophrenia
2.2
7.1
59
275
L17
ICPC
Foot/toe symptom/complaint
1.3
7.1
724
5980
R42
ICD-10 Finland
Dizziness and giddiness
1.3
7.1
523
4143
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.3
7.1
53
237
A28
ICPC
Limited function/disability NOS
1.4
7.1
319
2344
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
10.0
7.0
13
13
H53.4
ICD-10 Finland
Visual field defects
2.4
7.0
45
188
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
1.9
6.9
89
486
N05AB03
ATC
perphenazine; systemic, rectal
1.8
6.9
93
515
F82
ICD-10 Finland
Specific developmental disorder of motor function
5.8
6.9
18
31
G91.1
ICD-10 Finland
Obstructive hydrocephalus
5.8
6.9
18
31
N06AX21
ATC
duloxetine; oral
1.4
6.9
316
2328
T90
ICPC
Diabetes non-insulin dependent
1.3
6.8
501
3964
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.4
6.8
345
2582
R56.8
ICD-10 Finland
Other and unspecified convulsions
1.7
6.8
119
711
M54.4
ICD-10 Finland
Lumbago with sciatica
1.3
6.8
475
3732
R35
ICD-10 Finland
Polyuria
1.6
6.8
135
835
SPAT1216
SPAT
Assessment of functional ability
1.4
6.8
317
2343
N05AA01
ATC
chlorpromazine; systemic, rectal
2.6
6.8
37
143
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.0
6.8
73
376
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
6.8
731
6076
H50.39
ICD-10 Finland
Intermittent heterotropia
40.1
6.8
8
*
A02BC03
ATC
lansoprazole; oral
1.3
6.7
695
5745
G81.1
ICD-10 Finland
Spastic hemiplegia
16.7
6.7
10
6
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
2.3
6.7
50
223
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.5
6.7
178
1179
N03AX18
ATC
lacosamide; systemic
3.3
6.7
24
73
37520
ICD-8 Finland
Glaucoma, Secondary
22.6
6.7
9
*
F71.1
ICD-10 Finland
Moderate mental retardation, significant impairment of behaviour requiring attention or treatment
22.6
6.7
9
*
H03AA01
ATC
levothyroxine sodium; systemic
1.3
6.7
601
4887
S06.0
ICD-10 Finland
Concussion
1.4
6.6
267
1924
R4110
NOMESCO Finland
Physiotherapy
1.3
6.6
685
5666
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
3.6
6.6
21
59
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.5
6.6
235
1656
Z02.7
ICD-10 Finland
Issue of medical certificate
1.5
6.6
170
1121
H33.0
ICD-10 Finland
Retinal detachment with retinal break
2.1
6.6
62
305
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
2.8
6.5
32
117
F70.9
ICD-10 Finland
Mild mental retardation, Without mention of impairment of behaviour
10.0
6.5
12
12
ZXE00
NOMESCO Finland
One hour or less
1.2
6.5
1041
9027
H26.2
ICD-10 Finland
Complicated cataract
2.7
6.5
33
123
N06AX26
ATC
vortioxetine; oral
1.5
6.5
200
1369
WX720
NOMESCO Finland
Own respiration
1.7
6.5
114
684
ZYB04
NOMESCO Finland
Outreach service in patient’s home or everyday environment
3.7
6.5
20
55
A10BJ06
ATC
semaglutide; parenteral
1.7
6.5
124
761
M01AE03
ATC
ketoprofen; systemic, rectal
1.2
6.5
915
7834
T36
ICD-10 Finland
Poisoning by systemic antibiotics
1.7
6.4
120
731
XCW11
NOMESCO Finland
Assessment of strabismus
70.0
6.4
7
*
3656X
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA SECUNDARIA ALIA SEU NUD]
70.0
6.4
7
*
H40.0
ICD-10 Finland
Glaucoma suspect
1.5
6.4
165
1087
WX110
NOMESCO Finland
Infiltration anesthesia
1.2
6.4
2130
19820
R20.2
ICD-10 Finland
Paraesthesia of skin
1.5
6.3
177
1187
C03CA01
ATC
furosemide; systemic
1.3
6.3
547
4425
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.4
6.3
315
2355
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.3
6.3
368
2819
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.6
6.3
123
759
CE2W4
NOMESCO Finland
Eye movement mapping
9.3
6.3
12
13
K02.1
ICD-10 Finland
Caries of dentine
1.2
6.3
1754
16033
3782A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Intermittent heterotropia[STRABISMUS CONVERGENS INTERMITTENS]
+∞
6.3
6
*
3671A
ICD-9 Finland
Disorders of refraction and accommodation, Myopia
+∞
6.3
6
*
N02BE01
ATC
paracetamol; systemic, rectal
1.3
6.2
2638
25122
7433A
ICD-9 Finland
Congenital anomalies of eye, Congenital cataract and lens anomalies
26.7
6.2
8
*
34408
ICD-8 Finland
Other cerebral paralysis, Alia definita
26.7
6.2
8
*
3768
FHL
Eye examination under general anesthesia
26.7
6.2
8
*
H52.5
ICD-10 Finland
Disorders of accommodation
26.7
6.2
8
*
CD2S4
NOMESCO Finland
Photography of eye
3.7
6.2
19
52
P99
ICPC
Psychological disorders other
1.8
6.2
85
475
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.4
6.2
232
1650
R60.0
ICD-10 Finland
Localized oedema
1.4
6.1
258
1873
R5140
NOMESCO Finland
Monitoring the use of the aid
1.4
6.1
248
1789
R5130, ,
SPAT
7.7
6.1
13
17
G91.0
ICD-10 Finland
Communicating hydrocephalus
4.1
6.1
16
39
R53
ICD-10 Finland
Malaise and fatigue
1.3
6.0
618
5098
P29
ICPC
Psychological sympt/compl other
1.5
6.0
196
1357
Z01.8
ICD-10 Finland
Other specified special examinations
1.3
6.0
573
4687
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
1.8
6.0
83
465

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
99
398
2.53
16.27
5.3
5.6
386.81
368.86
umol/l
0.48
88
350
379
2492
1.59
14.74
8.0
8.0
1.57
1.07
mmol/l
1.83
291
1952
340
2213
1.60
13.77
8.3
8.5
95.57
95.93
%
0.56
327
2129
1103
8977
1.35
13.55
3.4
3.2
32.60
34.23
u/l
0.28
1042
8549
321
2070
1.61
13.51
8.4
8.7
123.03
122.76
g/l
0.08
310
2011
370
2487
1.55
13.02
8.2
8.0
5.21
5.10
kpa
1.51
347
2372
370
2488
1.55
12.99
8.2
8.0
12.26
12.78
kpa
1.01
347
2373
910
7238
1.36
12.86
3.2
2.8
—
—
—
0
0
756
5864
1.38
12.46
3.8
3.4
—
—
—
0
0
718
5533
1.38
12.30
4.6
3.7
1.02
1.02
kg/l
0.02
93
819
1399
11946
1.30
11.72
6.6
6.5
1.21
1.21
mmol/l
0.92
1202
10237
888
7136
1.34
11.49
2.2
2.1
207.50
218.78
u/l
0.09
826
6744
219
1348
1.67
11.08
8.8
7.0
24.79
24.52
mmol/l
0.44
207
1273
870
7004
1.33
11.04
3.5
3.8
7.39
7.40
ph
0.70
137
1339
2169
19718
1.30
10.78
6.8
7.3
78.43
77.14
u/l
0.69
2058
18671
1479
12827
1.28
10.61
3.9
3.4
0.00
0.00
estimate
1.47
251
2539
1473
12817
1.27
10.11
5.1
4.6
0.00
0.00
estimate
0.50
250
2429
1484
12942
1.27
9.93
3.9
3.4
0.01
0.00
estimate
0.17
245
2358
1651
14584
1.27
9.93
5.1
4.6
6.75
6.58
mmol/l
2.08
1544
13575
1259
10766
1.28
9.90
6.3
5.9
1.21
1.21
mmol/l
0.88
1166
9903
218
1390
1.61
9.61
6.2
4.9
—
—
—
0
0
417
3053
1.42
9.47
1.9
1.7
—
—
—
0
0
1132
9612
1.27
9.26
1.9
1.9
97.96
96.56
pmol/l
0.45
586
5066
1220
10459
1.27
9.20
4.5
4.8
35.89
36.11
g/l
0.66
1137
9786
2848
27106
1.40
9.13
16.0
13.6
139.68
139.66
mmol/l
0.21
2789
26429
2541
23819
1.30
8.70
17.6
14.9
16.23
14.60
%
0.48
2502
23412
1211
10429
1.26
8.64
3.6
3.1
5.63
5.88
ph
2.04
78
992
753
6132
1.30
8.45
4.3
4.2
—
—
—
0
0
2849
27208
1.37
8.14
15.9
13.7
3.95
3.95
mmol/l
0.16
2785
26475
1957
17844
1.24
8.12
3.7
3.4
—
—
—
0
0
1038
8879
1.25
7.63
3.3
3.2
37.91
47.77
ng/l
0.45
607
5305
2550
24057
1.28
7.38
19.8
15.5
332.46
332.77
g/l
0.91
2532
23896
139
850
1.66
7.30
5.3
5.2
1.71
1.64
%
0.36
129
788
2271
21164
1.24
7.19
4.6
4.0
14.70
14.59
pmol/l
1.29
2126
19599
2118
19597
1.23
7.15
4.3
3.9
11.18
10.91
mm/h
0.41
1994
18337
340
2521
1.39
7.14
2.0
2.1
378.33
371.51
nmol/l
0.27
321
2319
206
1402
1.50
6.85
10.1
10.2
0.71
0.67
%
0.68
206
1391
180
1192
1.54
6.81
9.1
11.1
—
—
—
0
0
119
712
1.70
6.80
5.8
6.0
1.40
1.27
mmol/l
0.67
104
610
204
1404
1.48
6.44
10.1
10.1
1.57
1.38
%
1.02
204
1394
1490
13406
1.21
6.34
6.7
6.0
0.04
0.04
e9/l
0.11
1305
11687
111
666
1.69
6.31
6.4
4.1
3.89
3.87
mmol/l
0.17
111
659
254
1836
1.42
6.19
2.2
2.3
7.47
7.12
ug/l
0.07
217
1640
1486
13394
1.20
6.13
6.6
6.0
0.58
0.56
e9/l
1.16
1303
11691
917
7903
1.22
6.00
2.6
2.5
55.09
68.31
u/l
0.71
844
7352
133
848
1.59
5.97
5.5
5.3
0.90
0.90
%
0.01
123
788
794
6749
1.23
5.92
4.5
3.7
0.00
0.00
estimate
1.49
239
2368
1531
13869
1.20
5.89
7.4
6.3
0.19
0.19
e9/l
0.72
1370
12296
1191
10549
1.20
5.85
11.9
12.6
1.15
1.20
inr
1.53
337
3190
1441
12992
1.20
5.82
5.4
6.1
11.17
11.30
umol/l
0.13
1368
12353
632
5249
1.25
5.81
1.5
1.5
19.96
20.65
nmol/l
0.64
558
4562
1526
13832
1.19
5.80
6.6
6.1
2.02
1.97
e9/l
0.24
1367
12369
101
607
1.69
5.74
1.7
1.6
11.19
30.93
e6/l
1.03
80
464
101
607
1.69
5.74
1.7
1.6
1952.29
1238.70
e6/l
0.30
85
487
1682
15389
1.19
5.73
10.7
9.2
4.16
4.02
e9/l
1.52
1477
13514
21
65
3.25
5.72
2.7
2.2
18.77
16.35
umol/l
0.38
21
65
199
1400
1.45
5.65
10.5
10.2
93.37
94.15
%
1.17
199
1393
611
5087
1.25
5.47
2.5
2.5
5.47
6.37
e6/l
0.94
550
4539
546
4511
1.25
5.22
3.6
3.4
379.13
461.36
ng/l
0.22
397
3136
2813
27118
1.27
5.21
14.4
12.5
22.28
21.86
mg/l
0.26
2261
21134
82
480
1.73
5.16
7.1
7.3
11.21
11.31
mmol/l
0.08
73
426
1210
10825
1.19
5.15
2.4
2.2
74.34
75.71
nmol/l
0.99
1125
9936
215
2914
0.72
5.14
4.6
4.1
31.24
31.93
%
0.42
157
2082
82
481
1.72
5.13
7.1
7.3
104.22
105.51
mmol/l
1.13
73
427
256
1932
1.35
4.85
3.7
3.3
—
—
—
0
0
1820
16906
1.17
4.78
4.9
4.0
1769.97
1775.03
e6/l
0.00
35
201
485
4001
1.25
4.68
1.7
1.7
1196.67
1167.43
nmol/l
0.31
393
3083
470
3873
1.25
4.58
3.2
3.7
0.82
0.82
mmol/l
0.41
446
3666
1381
12577
1.17
4.58
6.9
6.5
—
—
—
0
0
163
1154
1.43
4.53
9.9
10.9
24.52
24.29
mmol/l
0.46
153
1124
95
604
1.59
4.41
1.7
1.4
3.72
3.69
mmol/l
0.11
89
567
2597
24928
1.21
4.38
5.3
4.7
3.05
1.97
mu/l
0.64
2448
23254
579
4903
1.22
4.37
1.3
1.3
27.31
27.76
iu/ml
0.02
192
1584
775
6755
1.19
4.30
1.7
1.6
1.41
1.41
mmol/l
0.06
677
5803
276
2147
1.31
4.28
4.2
4.2
5.87
5.83
kpa
0.24
269
2087
90
570
1.60
4.26
1.7
1.6
—
—
—
0
0
847
7450
1.18
4.23
3.4
3.3
7.44
7.76
mmol/l
1.28
732
6435
245
1880
1.33
4.18
1.3
1.3
108.95
203.61
u/ml
4.51
229
1747
387
3152
1.26
4.18
5.3
5.9
1.07
1.05
mmol/l
0.37
367
2942
1915
17957
1.16
4.18
4.4
4.0
—
—
—
0
0
281
2201
1.30
4.14
4.1
4.1
—
7.38
—
0
13
2498
23929
1.19
4.13
5.7
5.0
39.55
38.97
mmol/mol
2.22
2355
22471
987
8818
1.17
4.05
3.6
3.5
71.76
92.39
e6/l
0.66
704
6079
228
1740
1.33
4.05
1.5
1.4
—
—
—
0
0
258
2010
1.31
3.97
7.8
7.9
1.29
1.36
mmol/l
0.53
245
1959
272
2136
1.30
3.95
4.1
4.2
1.90
1.84
mmol/l
0.10
226
1771
923
8226
1.17
3.88
2.9
3.3
2.35
2.35
mmol/l
0.02
819
7380
835
7383
1.18
3.87
3.1
3.1
42.05
82.29
e6/l
1.71
658
5604
768
6756
1.18
3.78
3.0
3.0
0.44
0.40
e6/l
0.16
598
5074
786
6928
1.18
3.78
3.8
3.8
13.13
8.86
mg/mmol
0.75
500
4422
11
24
4.60
3.74
10.9
10.2
—
—
—
0
0
767
6765
1.17
3.64
8.7
6.8
—
—
—
0
0
561
4821
1.20
3.60
2.6
2.8
540.66
540.18
mosm/kgh2o
0.02
473
4127
484
4102
1.21
3.60
2.6
2.6
0.98
1.31
e6/l
1.01
280
2276
1323
12168
1.15
3.57
6.8
6.2
0.68
0.68
%
0.07
1244
11404
673
5884
1.18
3.55
3.2
3.0
1038.32
1167.72
ng/l
0.51
567
4925
123
869
1.43
3.53
6.9
4.8
—
—
—
0
0
457
3860
1.21
3.52
1.3
1.4
492.27
542.82
titre
0.23
88
787
2919
28469
1.24
3.52
13.4
11.5
—
—
—
0
0
228
1778
1.30
3.51
4.1
3.7
5.04
4.74
kpa
0.99
221
1721
1362
12566
1.14
3.48
6.8
6.2
2.82
2.83
%
0.03
1285
11809
222
1731
1.30
3.43
2.8
2.9
118.57
180.91
ng/l
3.19
197
1553
754
6676
1.17
3.39
2.9
2.9
—
—
—
0
0
745
6595
1.17
3.36
3.2
3.3
490.99
381.80
mg/l
0.23
480
4221
248
1968
1.28
3.35
9.1
9.1
—
—
—
0
0
107
745
1.45
3.34
1.1
1.3
90.00
130.33
titre
0.41
16
60
1369
12661
1.14
3.34
7.2
6.5
8.36
8.39
%
0.12
1293
11919
102
709
1.45
3.22
1.4
1.3
—
—
—
0
0
1392
12909
1.14
3.22
6.6
6.0
56.90
56.49
%
0.64
1311
12175
32
164
1.96
3.19
2.5
1.9
—
—
—
0
0
1327
12277
1.14
3.17
3.1
2.8
105.01
106.53
ug/l
0.08
1249
11528
25
117
2.15
3.16
4.0
2.2
142.70
154.89
nmol/l
0.34
20
102
253
2030
1.27
3.14
2.5
2.7
10.56
10.52
g/l
0.06
234
1866
41
231
1.78
3.08
1.2
1.2
38.23
39.55
mg/l
0.08
33
190
40
224
1.80
3.06
1.1
1.1
232.77
267.63
mg/l
0.47
35
192
34
181
1.89
3.05
1.6
1.5
—
—
—
0
0
1406
13089
1.13
2.99
6.8
6.2
28.67
28.94
%
0.40
1332
12360
355
2977
1.22
2.96
2.6
2.9
8.95
7.53
umol/l
0.34
296
2584
439
3759
1.19
2.94
2.5
2.4
12.92
13.84
umol/l
2.11
413
3521
414
3529
1.20
2.91
2.1
2.0
—
—
—
0
0
570
5007
1.17
2.81
1.7
1.6
76000454.57
31541058.19
pmol/l
0.56
500
4258
128
957
1.35
2.71
3.8
3.3
—
—
—
0
0
47
288
1.64
2.66
2.3
2.0
—
—
—
0
0
227
1839
1.25
2.64
3.6
3.2
4.44
4.52
pmol/l
0.65
209
1636
12
41
2.93
2.61
1.4
1.6
—
—
—
0
0
101
732
1.39
2.60
2.0
1.9
4.00
4.19
iu/l
0.07
44
273
10
30
3.34
2.60
1.6
1.3
—
—
—
0
0
182
2283
0.79
2.60
3.6
4.0
—
—
—
0
0
27
142
1.91
2.55
1.1
1.1
—
7.65
nmol/l
—
0
26
12
44
2.73
2.54
1.0
1.2
—
—
—
0
0
12
44
2.73
2.54
1.0
1.2
—
—
—
0
0
12
44
2.73
2.54
1.0
1.2
—
—
—
0
0
153
1191
1.30
2.47
1.1
1.1
1.28
0.89
u/ml
—
6
15
528
4661
1.16
2.44
1.4
1.3
5.74
10.08
u/ml
1.28
205
1910
372
3198
1.18
2.40
2.5
2.5
21.97
23.74
%
1.68
299
2769
976
10567
0.89
2.38
2.8
2.5
—
—
—
0
0
686
6182
1.14
2.36
2.4
2.2
2.79
2.86
mg/l
0.30
606
5291
713
6442
1.14
2.36
3.9
4.0
90.83
92.79
%
1.31
693
6280
3098
30565
1.27
2.35
21.6
18.1
90.33
90.53
fl
1.69
3062
30204
155
1218
1.29
2.35
1.4
1.6
358.56
287.55
mu/l
1.42
141
1094
3096
30544
1.27
2.34
21.7
18.2
258.58
257.36
e9/l
0.48
3025
29860
74
518
1.44
2.34
2.7
3.1
31.85
36.35
umol/l
0.84
67
475
3099
30581
1.27
2.31
21.8
18.3
135.94
136.07
g/l
0.20
3062
30211
3098
30571
1.27
2.30
21.7
18.2
4.54
4.53
e12/l
0.76
3020
29825
3098
30572
1.27
2.29
21.7
18.2
6.78
6.67
e9/l
1.10
3022
29817
46
293
1.58
2.27
1.8
1.7
—
—
—
0
0
8
23
3.48
2.27
1.1
1.1
—
—
—
0
0
3097
30565
1.26
2.26
21.6
18.1
30.11
30.19
pg
1.86
3061
30201
1983
19008
1.11
2.25
3.4
3.0
46.80
44.29
u/l
0.38
1889
18010
25
135
1.86
2.22
3.8
2.9
146.00
179.88
umol/l
0.25
17
73
3092
30515
1.26
2.22
21.8
18.3
40.46
40.39
%
0.29
2875
28883
353
3046
1.18
2.20
1.5
1.4
—
—
—
0
0
396
3451
1.17
2.18
2.5
2.4
2.43
2.39
g/l
0.91
366
3216
84
613
1.38
2.13
4.3
3.1
—
—
—
0
0
128
997
1.30
2.10
3.7
3.3
0.67
0.65
%
0.22
128
992
2620
25542
1.13
2.10
4.5
4.0
5.89
5.82
mmol/l
1.53
2443
23667
138
1087
1.28
2.09
1.3
1.3
0.25
0.93
u/ml
1.55
11
92
5
10
5.01
2.07
3.8
4.4
—
—
—
0
0
194
1592
1.23
2.07
1.6
1.8
1.19
1.38
g/l
1.33
181
1475
41
263
1.57
2.00
1.6
1.5
286.55
282.07
mosm/kgh2o
0.59
31
201
2935
28872
1.17
1.89
10.5
9.6
27.70
26.71
u/l
1.33
2856
28032
477
4261
1.14
1.89
2.7
2.9
2.44
2.44
mmol/l
0.16
406
3740
172
2085
0.82
1.87
1.4
1.4
—
—
—
0
0
717
6577
1.12
1.83
2.3
2.5
1894.02
4211.18
umol/l
1.61
626
5874
240
2042
1.19
1.80
6.6
8.2
8.54
8.77
mmol/l
0.21
225
1962
211
1775
1.20
1.79
1.2
1.2
—
—
—
0
0
55
387
1.43
1.77
2.7
2.9
—
—
—
0
0
215
1815
1.20
1.76
1.3
1.4
32.50
28.64
iu/l
0.89
174
1551
104
813
1.29
1.72
1.1
1.2
—
—
—
0
0
431
3851
1.14
1.71
2.7
2.8
3.90
3.00
e6/l
0.51
223
2042
81
613
1.33
1.69
1.2
1.2
50.03
40.67
u/ml
0.24
14
66
397
3531
1.14
1.69
1.6
1.6
—
—
—
0
0
95
736
1.30
1.68
1.2
1.2
2.57
7.12
u/ml
1.60
12
124
67
496
1.36
1.63
4.6
3.6
—
—
—
0
0
1254
11886
1.09
1.61
9.9
9.1
0.00
0.00
e9/l
0.07
1020
9715
19
106
1.80
1.58
1.2
1.1
0.15
1.83
u/ml
1.31
13
59
20
114
1.76
1.56
2.6
3.2
7.41
7.42
ph
—
6
35
109
870
1.26
1.55
1.4
1.7
1.27
1.18
g/l
2.37
99
818
92
720
1.29
1.54
3.1
3.0
—
—
—
0
0
707
6540
1.10
1.53
1.3
1.3
1.16
1.66
u/ml
1.07
206
1764
621
5709
1.11
1.52
1.4
1.5
2.43
2.28
g/l
1.06
378
3568
105
837
1.26
1.52
1.1
1.1
1.06
4.76
u/ml
2.68
18
122
279
2442
1.16
1.51
2.4
2.5
33.85
59.24
u/l
0.70
229
2108
181
1529
1.19
1.51
4.3
4.1
5.17
5.15
kpa
0.11
176
1465
105
838
1.26
1.51
2.8
2.0
1.59
1.95
ug/l
0.24
97
755
651
6005
1.11
1.50
1.8
1.9
1.09
1.07
mg/l
0.07
487
4469
105
839
1.26
1.49
1.4
1.8
0.25
0.23
g/l
0.96
95
788
92
724
1.28
1.48
1.3
1.2
6.25
7.14
u/ml
0.07
11
77
148
1230
1.21
1.47
3.9
4.6
24.36
24.05
mmol/l
0.60
143
1208
28
427
0.65
1.46
1.0
1.1
0.02
0.25
u/ml
2.29
11
127
18
102
1.77
1.44
1.8
1.7
—
—
—
0
0
11
52
2.12
1.44
1.4
1.4
—
—
—
0
0
178
1513
1.19
1.40
4.3
4.1
7.41
7.41
ph
0.01
23
180
189
1615
1.18
1.40
1.2
1.2
—
—
—
0
0
141
1173
1.21
1.40
1.1
1.1
—
—
—
0
0
27
173
1.57
1.40
1.1
1.5
—
—
—
0
0
6
138
0.43
1.39
1.0
1.2
—
—
—
0
0
7
29
2.42
1.39
1.1
1.2
1.42
1.78
umol/24h
—
7
29
19
111
1.72
1.39
1.2
1.7
—
—
—
0
0
52
381
1.37
1.38
1.3
1.4
63.53
63.11
mmol/l
0.02
38
313
132
1094
1.22
1.37
1.3
1.3
204.91
226.33
miu/ml
0.25
47
548
275
2427
1.15
1.35
2.6
2.7
1.71
1.78
%
0.66
246
2168
123
1015
1.22
1.34
2.2
2.5
20.69
21.29
s
0.93
104
877
132
1100
1.21
1.31
3.2
2.3
—
—
—
0
0
33
225
1.47
1.31
1.5
1.4
3266.50
97544.90
e6/l
1.39
24
154
12
62
1.94
1.27
1.2
1.4
52.00
31.27
%
—
5
41
25
162
1.55
1.25
1.1
1.1
—
—
—
0
0
395
3586
1.12
1.25
2.1
2.4
29.54
29.73
s
0.30
385
3463
201
1746
1.16
1.25
3.7
3.8
87.83
80.74
ng/l
0.47
180
1535
8
36
2.23
1.24
1.3
1.8
73.75
102.78
ng/l
—
8
36
199
1732
1.16
1.21
2.2
2.6
66.35
66.73
g/l
0.28
186
1593
163
1398
1.17
1.20
1.8
2.3
—
—
—
0
0
28
189
1.49
1.18
1.1
1.4
82803.68
81527.00
e6/l
0.01
19
113
203
1773
1.15
1.18
2.9
2.8
71.08
71.28
e9/l
0.03
150
1324
6
127
0.47
1.16
2.8
2.7
2091.67
2001.70
ml
—
6
115
6
127
0.47
1.16
1.2
1.1
—
—
—
0
0
31
215
1.45
1.15
1.1
1.4
2736.75
2651.97
e6/l
0.03
24
151
266
2372
1.13
1.15
1.2
1.2
—
—
—
0
0
74
589
1.26
1.15
1.6
1.9
190.44
200.82
pmol/l
0.46
68
556
15
87
1.73
1.15
1.8
2.3
—
—
—
0
0
68
536
1.27
1.14
1.5
1.4
20.77
26.46
u/l
0.89
56
438
8
152
0.53
1.14
1.1
1.4
140.50
132.25
nmol/l
—
8
152
73
582
1.26
1.12
1.7
1.7
19475.94
12467.99
e6/l
0.45
54
417
74
591
1.26
1.12
1.5
1.4
—
—
—
0
0
569
6107
0.92
1.11
2.2
2.2
—
—
—
0
0
65
512
1.28
1.10
2.1
2.3
135.38
131.36
g/l
0.69
50
379
80
647
1.24
1.09
3.0
2.3
—
—
—
0
0
89
730
1.23
1.07
1.8
2.3
10.65
10.31
g/l
0.29
82
661
69
550
1.26
1.07
1.6
1.4
109.10
116.05
u/ml
0.30
27
106
768
7245
1.08
1.07
3.4
3.0
—
—
—
0
0
168
1462
1.16
1.05
1.1
1.1
358.33
120.72
titre
—
6
36
185
1624
1.15
1.03
3.1
2.7
—
—
—
0
0
134
1148
1.17
1.03
3.4
3.2
—
—
—
0
0
142
1223
1.17
1.02
2.4
2.3
—
—
—
0
0
66
527
1.26
1.02
4.0
4.2
—
—
—
0
0
34
462
0.73
1.02
1.0
1.1
3.76
3.97
u/ml
0.03
19
183
36
264
1.37
1.01
1.0
1.1
—
—
—
0
0
35
472
0.74
1.00
1.8
1.7
—
—
—
0
0
18
115
1.57
0.99
1.8
2.3
—
—
—
0
0
38
503
0.75
0.97
1.1
1.1
4.05
4.96
u/ml
0.23
22
228
11
186
0.59
0.95
1.0
1.2
—
—
—
0
0
74
605
1.23
0.95
1.3
1.3
246.72
262.05
u/ml
0.22
47
371
0
32
0.00
0.95
0.0
1.0
—
—
—
0
0
51
399
1.28
0.95
1.5
1.5
—
—
—
0
0
43
557
0.77
0.94
2.1
2.2
0.76
0.83
nmol/l
0.31
37
472
29
208
1.40
0.94
1.1
1.0
—
—
—
0
0
6
117
0.51
0.94
1.0
1.2
—
—
—
0
0
52
409
1.28
0.93
3.6
3.0
7.44
7.28
mmol/l
0.10
52
398
12
70
1.72
0.92
1.6
1.4
36.92
49.51
%
0.51
12
60
206
1839
1.13
0.92
2.4
2.2
12.46
12.67
nmol/l
0.14
190
1657
150
1312
1.15
0.91
1.1
1.1
—
—
—
0
0
12
195
0.61
0.90
1.0
1.0
0.08
2.05
u/ml
—
6
48
90
756
1.20
0.89
1.2
1.2
—
—
—
0
0
35
262
1.34
0.89
1.1
1.1
—
—
—
0
0
633
6700
0.93
0.88
3.5
3.5
—
—
—
0
0
10
56
1.79
0.87
1.0
1.2
—
—
—
0
0
55
440
1.25
0.87
3.5
2.9
1.57
1.50
mmol/l
0.24
55
425
20
136
1.47
0.86
1.1
1.0
747.75
759.53
ng/l
0.04
12
89
94
1105
0.85
0.86
1.5
1.4
—
—
—
0
0
159
1405
1.14
0.85
3.1
2.2
—
—
—
0
0
51
406
1.26
0.85
2.5
1.5
—
—
—
0
0
321
3486
0.91
0.85
1.3
1.3
—
—
—
0
0
20
137
1.46
0.84
1.1
1.0
282.42
302.35
ng/l
0.13
12
92
61
744
0.82
0.83
1.4
1.5
—
—
—
0
0
19
129
1.48
0.83
1.3
1.5
9.58
13.72
u/l
3.37
19
124
1038
10786
0.94
0.81
1.9
2.0
—
—
—
0
0
57
464
1.23
0.79
2.2
2.8
—
—
—
0
0
88
748
1.18
0.79
6.0
5.3
1.43
1.40
mg/l
0.14
80
707
384
3572
1.09
0.79
2.2
2.5
116.44
119.39
ug/g
0.06
302
2883
17
247
0.69
0.79
1.0
1.2
—
—
—
0
0
0
26
0.00
0.78
0.0
1.3
—
—
—
0
0
159
1415
1.13
0.78
3.1
2.2
—
—
—
0
0
5
96
0.52
0.78
2.4
2.8
—
—
—
0
0
344
3192
1.09
0.76
1.6
1.7
—
—
—
0
0
27
200
1.35
0.76
1.6
2.3
—
—
—
0
0
10
161
0.62
0.75
2.2
1.3
—
—
—
0
0
18
124
1.45
0.75
1.8
2.0
2.29
2.72
ug/l
0.13
12
106
159
1420
1.13
0.74
3.1
2.2
—
—
—
0
0
5
24
2.08
0.74
1.0
1.1
—
—
—
0
0
740
7743
0.94
0.73
1.5
1.5
—
—
—
0
0
1253
12142
1.05
0.73
2.5
2.5
—
—
—
0
0
22
300
0.73
0.73
1.1
1.3
—
—
nmol/l
—
0
0
58
479
1.21
0.72
1.1
1.1
—
—
—
0
0
14
207
0.67
0.72
1.9
1.3
1.58
1.56
g/l
0.08
14
207
60
720
0.83
0.72
1.4
1.4
—
—
—
0
0
6
110
0.54
0.72
2.3
2.0
—
—
—
0
0
12
76
1.58
0.71
1.4
1.4
—
—
—
0
0
16
109
1.47
0.70
3.0
2.7
—
—
—
0
0
195
2143
0.90
0.69
1.3
1.4
—
—
—
0
0
60
716
0.83
0.69
1.4
1.4
—
—
—
0
0
17
118
1.44
0.69
2.8
2.3
34.80
86.88
ug/l
0.36
17
106
27
204
1.33
0.68
1.0
1.1
361.25
394.41
nmol/l
0.34
20
189
146
1307
1.12
0.67
3.3
2.3
—
—
—
0
0
14
202
0.69
0.65
1.0
2.1
—
—
—
0
0
514
4874
1.06
0.65
1.6
1.6
—
—
—
0
0
35
278
1.26
0.63
1.5
1.6
50.17
60.15
%
0.75
23
173
13
189
0.69
0.63
2.0
2.1
0.63
1.73
u/field
—
8
86
28
216
1.30
0.63
3.6
1.9
34.52
19.66
ug/l
0.47
28
211
24
314
0.76
0.63
1.0
1.3
—
—
—
0
0
17
234
0.73
0.62
3.6
2.8
—
—
—
0
0
14
96
1.46
0.61
1.0
1.1
—
—
—
0
0
48
398
1.21
0.60
1.3
1.5
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
9.14
—
0
7
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
3.4
—
0.64
—
0
7
41
335
1.23
0.59
1.3
1.5
—
—
—
0
0
20
266
0.75
0.59
3.0
3.8
—
—
—
0
0
0
22
0.00
0.59
0.0
1.5
—
344.09
—
0
22
25
192
1.30
0.59
1.9
5.1
12.47
11.47
%
0.59
25
192
14
97
1.45
0.59
1.4
1.4
—
—
—
0
0
208
1916
1.09
0.58
2.4
3.6
1.22
1.23
mmol/l
0.43
177
1665
331
3523
0.93
0.58
1.5
1.4
—
—
—
0
0
153
1389
1.11
0.58
3.2
2.2
—
—
—
0
0
6
35
1.72
0.57
5.3
2.7
—
—
—
0
0
22
286
0.77
0.56
5.0
4.6
12.87
79.35
u/ml
—
6
84
19
141
1.35
0.56
1.1
1.1
1810.32
1570.18
miu/ml
0.34
19
141
60
513
1.17
0.56
3.4
3.4
26.34
23.98
mg/l
0.15
38
322
17
124
1.37
0.55
2.3
2.0
1.71
1.87
umol/l
0.39
17
116
249
2318
1.08
0.55
2.2
2.4
0.22
0.22
g/l
0.05
237
2178
623
5976
1.05
0.55
4.4
4.3
2.74
2.28
ug/l
0.52
557
5396
9
60
1.50
0.54
1.1
1.4
1.97
1.04
u/ml
—
9
60
26
204
1.28
0.54
1.8
1.5
37.19
34.38
%
0.14
20
120
21
160
1.31
0.53
1.0
1.2
—
—
—
0
0
15
108
1.39
0.53
1.2
1.0
—
—
—
0
0
214
1986
1.08
0.52
3.6
4.2
0.79
0.65
%
0.44
62
631
22
282
0.78
0.52
1.0
1.1
—
—
—
0
0
102
913
1.12
0.51
1.4
1.4
13.06
10.21
u/l
0.89
78
736
126
1142
1.11
0.51
2.5
1.8
—
—
—
0
0
30
242
1.24
0.51
2.6
2.5
—
—
—
0
0
14
191
0.73
0.50
1.1
1.4
74.43
76.63
umol/l
0.15
14
191
232
2165
1.08
0.50
4.1
4.4
1.02
0.90
%
0.32
71
717
23
180
1.28
0.49
1.2
1.5
—
—
—
0
0
27
216
1.25
0.49
1.5
1.3
1.34
1.45
nmol/l
0.17
21
194
56
483
1.16
0.49
1.1
1.1
—
—
—
0
0
780
8058
0.96
0.48
2.3
2.3
—
—
—
0
0
40
335
1.20
0.48
1.5
2.6
—
—
—
0
0
54
465
1.16
0.48
1.1
1.1
1.24
2.76
u/ml
2.36
28
235
81
719
1.13
0.48
2.5
2.1
9.42
11.02
mg/l
1.11
76
668
116
1052
1.11
0.48
1.8
1.6
47.68
9.60
u/ml
—
5
33
22
278
0.79
0.47
4.4
2.2
—
—
—
0
0
26
209
1.25
0.46
1.1
1.2
—
65.78
—
0
12
55
477
1.16
0.45
2.1
2.6
16.93
16.55
%
0.26
32
239
244
2292
1.07
0.45
1.4
1.5
—
—
—
0
0
33
274
1.21
0.44
1.6
2.6
—
—
—
0
0
56
641
0.87
0.44
1.2
1.3
—
—
—
0
0
48
413
1.16
0.44
2.4
2.5
4.99
6.38
umol/l
0.67
36
305
104
943
1.11
0.44
1.6
1.8
1.53
1.52
g/l
0.04
91
829
181
1941
0.93
0.43
2.5
2.7
4.60
5.06
e9/l
0.29
154
1643
5
31
1.61
0.43
1.0
1.1
—
—
—
0
0
17
218
0.78
0.42
1.1
1.1
1.17
1.46
u/ml
—
8
63
0
15
0.00
0.41
0.0
3.4
—
—
—
0
0
26
213
1.22
0.40
1.3
1.1
—
—
—
0
0
31
259
1.20
0.40
4.4
4.2
6.28
7.14
mmol/l
1.16
21
223
46
529
0.87
0.40
1.1
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
5
35
1.43
0.39
1.0
1.1
—
—
—
0
0
69
617
1.12
0.39
1.9
2.2
39.16
38.01
g/l
1.12
63
551
46
526
0.87
0.38
1.1
1.1
—
—
—
0
0
189
1776
1.07
0.37
1.3
1.3
43.41
50.17
au/ml
—
7
96
8
112
0.71
0.37
1.6
1.3
—
—
—
0
0
149
1389
1.08
0.37
2.5
2.2
1416.85
5137.27
u/l
3.02
51
548
10
72
1.39
0.37
1.5
1.5
10.80
12.55
g/l
—
5
55
69
620
1.12
0.36
1.3
1.2
—
—
—
0
0
80
726
1.10
0.36
1.8
2.6
—
—
—
0
0
29
342
0.85
0.35
1.1
1.3
—
0.38
nmol/l
—
0
24
5
79
0.63
0.35
1.2
1.1
—
—
—
0
0
13
99
1.31
0.35
1.1
1.3
—
—
—
0
0
9
122
0.74
0.35
1.0
1.3
152.44
166.16
mmol/24h
—
9
122
6
45
1.33
0.33
1.0
1.4
—
—
—
0
0
269
2818
0.95
0.33
1.5
1.4
—
—
—
0
0
84
768
1.10
0.33
1.8
2.5
2864.07
389.90
ug/l
0.50
75
715
17
210
0.81
0.33
1.5
1.5
—
—
—
0
0
14
177
0.79
0.33
6.7
6.6
—
—
—
0
0
26
219
1.19
0.33
2.8
3.2
311.47
43.20
mg/l
0.50
13
162
207
1962
1.06
0.33
4.3
4.5
0.02
0.41
%
1.03
48
515
108
1001
1.08
0.32
1.3
1.2
—
—
—
0
0
122
1137
1.08
0.32
5.0
4.2
—
—
—
0
0
11
83
1.33
0.32
1.5
1.7
—
—
—
0
0
12
154
0.78
0.32
1.7
2.4
501.86
498.41
min
—
7
114
53
591
0.90
0.31
1.1
1.1
0.82
1.56
u/ml
0.60
35
296
41
461
0.89
0.29
1.6
1.7
0.47
0.79
g/l
2.89
33
350
204
1943
1.05
0.28
2.4
2.4
17.54
22.35
au/ml
0.50
16
178
50
450
1.11
0.28
1.3
1.3
3.67
5.04
u/ml
0.51
24
195
180
1894
0.95
0.28
1.8
1.7
—
—
—
0
0
90
837
1.08
0.26
2.7
3.8
0.30
0.30
g/l
0.01
43
378
20
169
1.18
0.25
4.1
2.9
44250.00
40384.31
ug/l
0.66
20
169
49
444
1.11
0.25
1.6
3.6
—
—
—
0
0
99
1055
0.94
0.24
1.7
1.6
—
—
—
0
0
56
513
1.09
0.24
1.3
1.1
—
13.16
—
0
37
40
360
1.11
0.23
2.8
3.2
0.82
0.83
nmol/l
0.10
35
281
69
639
1.08
0.23
1.1
1.1
3.19
5.53
u/ml
1.08
43
340
5
38
1.32
0.23
1.0
1.3
—
8.42
—
0
14
5
40
1.25
0.22
1.0
1.3
—
—
—
0
0
341
3511
0.97
0.22
2.8
2.8
0.84
0.70
ug/l
0.50
215
2100
108
1021
1.06
0.22
5.4
4.4
24.73
24.74
mmol/l
0.02
102
957
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
132.17
—
0
6
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
5.1
—
388.17
—
0
12
43
471
0.91
0.21
1.3
1.2
—
—
—
0
0
111
1052
1.06
0.21
1.2
1.2
—
—
—
0
0
5
43
1.16
0.21
1.2
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
69.89
—
0
9
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
6
48
1.25
0.20
1.0
1.0
—
—
—
0
0
6
48
1.25
0.20
1.7
1.5
—
—
—
0
0
75
703
1.07
0.20
1.1
1.1
1.38
2.45
u/ml
0.91
45
369
18
208
0.86
0.20
1.2
1.4
204.46
215.33
pmol/l
0.08
18
208
24
271
0.88
0.20
1.0
1.4
—
—
—
0
0
12
99
1.21
0.19
1.2
1.2
—
0.10
—
0
7
19
218
0.87
0.19
2.5
3.1
64.86
55.14
%
1.41
14
192
53
491
1.08
0.19
2.5
3.8
—
—
—
0
0
11
90
1.22
0.19
1.5
1.3
—
—
—
0
0
10
122
0.82
0.19
1.1
1.7
—
—
—
0
0
21
184
1.14
0.19
1.1
1.2
1.09
1.04
ratio
—
6
71
18
206
0.87
0.18
1.1
1.3
—
—
—
0
0
62
580
1.07
0.18
1.1
1.4
—
—
—
0
0
7
61
1.15
0.17
1.4
1.1
—
—
—
0
0
43
465
0.92
0.17
1.0
1.1
3.67
18175.35
iu/ml
—
6
129
2637
26473
0.98
0.17
4.3
4.0
1.44
1.47
mmol/l
4.06
2488
24884
20
226
0.88
0.17
1.1
1.0
—
—
—
0
0
22
196
1.12
0.16
1.1
1.1
—
—
—
0
0
8
70
1.14
0.16
1.9
2.2
—
—
—
0
0
6
77
0.78
0.15
3.0
3.1
—
—
—
0
0
9
78
1.15
0.15
7.7
10.7
—
—
—
0
0
76
800
0.95
0.15
2.4
3.7
246.06
1927.27
u/ml
0.74
64
685
226
2199
1.03
0.15
4.4
3.7
—
—
—
0
0
9
82
1.10
0.15
1.0
1.1
—
—
—
0
0
55
518
1.06
0.14
3.6
3.6
57.93
57.29
%
0.16
55
518
33
357
0.92
0.14
1.8
3.4
1.23
1.42
%
0.15
28
326
12
103
1.17
0.13
2.2
1.5
14.83
14.91
pmol/l
0.02
12
86
20
180
1.11
0.13
1.2
1.3
32.76
32.86
nmol/l
0.00
14
155
9
106
0.85
0.13
1.2
1.4
—
—
—
0
0
287
2812
1.02
0.12
1.3
1.3
—
—
—
0
0
17
189
0.90
0.12
1.4
1.6
—
—
—
0
0
2702
26948
1.02
0.11
4.8
4.4
2.82
2.86
mmol/l
1.55
2548
25298
43
405
1.06
0.11
1.2
1.2
—
—
—
0
0
64
611
1.05
0.11
1.1
1.1
0.33
1.30
u/ml
1.99
30
272
88
847
1.04
0.11
9.6
8.5
—
—
—
0
0
67
700
0.96
0.11
1.4
1.4
265.06
301.25
ug/g
0.61
37
381
2547
25543
0.99
0.11
3.9
3.6
1.32
1.29
mmol/l
1.41
2394
23871
211
2065
1.02
0.10
4.3
4.5
0.17
0.12
%
0.30
52
616
14
156
0.90
0.10
6.1
3.4
—
—
—
0
0
24
222
1.08
0.10
3.9
2.7
808.29
762.03
e6/l
0.18
24
216
12
106
1.13
0.09
2.1
2.6
—
—
—
0
0
220
2243
0.98
0.09
2.9
4.1
8.70
19.72
ug/l
1.33
158
1784
44
418
1.05
0.09
1.3
1.7
—
—
—
0
0
31
330
0.94
0.09
1.1
1.2
—
—
—
0
0
19
174
1.09
0.09
3.8
2.8
42.75
44.00
%
0.10
12
86
220
2159
1.02
0.09
1.2
1.2
122.30
156.40
iu/ml
0.71
84
824
5
48
1.04
0.09
1.2
1.9
—
—
—
0
0
25
233
1.07
0.09
4.1
3.1
—
—
—
0
0
44
420
1.05
0.08
1.3
1.4
2.56
4.25
ug/l
1.28
35
377
591
5965
0.99
0.08
2.0
1.9
—
—
—
0
0
24
224
1.07
0.08
1.2
1.2
1.99
1.77
u/ml
0.05
13
114
52
499
1.04
0.08
1.1
1.2
—
—
—
0
0
2657
26624
0.99
0.08
4.4
4.0
4.70
4.77
mmol/l
2.98
2514
25142
35
332
1.05
0.08
1.1
1.3
—
—
—
0
0
7
68
1.03
0.07
1.4
1.5
65.86
60.56
%
—
7
55
24
225
1.07
0.07
1.1
1.2
—
62.86
—
0
7
8
76
1.05
0.07
2.0
1.5
—
—
—
0
0
56
540
1.04
0.07
2.1
2.5
80.10
98.30
ug/min
0.22
33
333
8
77
1.04
0.07
1.8
1.6
—
—
—
0
0
55
531
1.04
0.07
5.2
3.9
3.01
2.48
mmol/l
0.49
40
344
8
92
0.87
0.06
1.1
1.7
—
—
—
0
0
30
285
1.05
0.06
1.7
1.4
6.53
6.76
g/l
0.11
23
197
9
100
0.90
0.06
1.1
1.1
—
—
—
0
0
9
102
0.88
0.06
1.0
1.0
—
—
—
0
0
9
102
0.88
0.06
1.1
1.1
—
—
—
0
0
9
104
0.87
0.06
1.3
1.6
—
—
—
0
0
331
3276
1.01
0.06
1.8
1.7
—
—
—
0
0
22
207
1.06
0.06
1.3
2.0
8.09
6.73
mmol/l
0.61
15
144
30
286
1.05
0.06
1.7
1.4
—
—
—
0
0
11
121
0.91
0.06
1.2
1.0
—
—
—
0
0
326
3292
0.99
0.05
1.2
1.2
—
—
—
0
0
34
326
1.04
0.05
1.1
1.2
—
—
—
0
0
38
366
1.04
0.05
1.4
1.9
—
950.00
—
0
16
43
444
0.97
0.04
1.6
1.8
—
—
—
0
0
36
347
1.04
0.04
2.1
2.5
—
—
—
0
0
30
288
1.04
0.04
1.1
1.5
678.04
377.46
pmol/l
0.61
25
256
10
91
1.10
0.04
1.3
1.4
82.18
87.14
nmol/24h
—
10
91
22
231
0.95
0.04
2.5
2.6
2.04
1.73
g/24h
—
10
121
58
594
0.98
0.04
1.9
3.5
39.73
46.12
mg/l
0.19
44
484
58
593
0.98
0.03
1.9
3.4
39.17
65.82
mg/l
1.21
43
482
14
131
1.07
0.03
1.1
1.1
139.08
193.69
iu/ml
0.80
14
131
55
538
1.02
0.03
1.3
1.5
0.62
0.42
nmol/l
0.32
38
422
42
429
0.98
0.02
2.0
1.6
—
—
—
0
0
66
669
0.99
0.01
1.1
1.1
—
—
—
0
0
21
203
1.03
0.01
1.0
1.1
18.50
10.90
iu/ml
—
7
52
63
638
0.99
0.01
4.8
3.7
7.42
7.42
ph
0.01
56
570
36
367
0.98
0.01
3.2
3.1
4.92
81.28
u/ml
1.01
36
360
29
284
1.02
0.00
1.7
1.4
0.43
0.37
g/l
0.24
22
195
29
284
1.02
0.00
1.7
1.4
3.05
2.90
g/l
0.12
22
197
38
374
1.02
0.00
1.3
1.7
—
—
—
0
0
12
124
0.97
0.00
1.5
1.5
—
—
—
0
0
21
214
0.98
0.00
1.0
1.1
7.54
2.38
u/ml
0.31
12
80
348
3479
1.00
0.00
1.2
1.2
—
—
—
0
0
11
108
1.02
0.00
1.1
1.1
—
—
—
0
0
16
158
1.01
0.00
1.4
1.5
16.44
24.72
umol/l
0.86
16
150
19
192
0.99
0.00
2.1
2.5
690.91
618.30
ml
0.27
11
133
20
202
0.99
0.00
1.1
1.1
—
—
—
0
0
44
442
1.00
0.00
1.5
1.6
—
—
—
0
0
22
217
1.01
0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
68.97
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
19
190
1.00
-0.00
1.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.3
3.10
3.52
mmol/l
—
5
44
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
7
75
0.93
-0.00
1.7
2.1
—
196.87
—
0
9
6
68
0.88
-0.00
1.0
1.1
0.35
5.24
u/ml
—
6
58
8
89
0.90
-0.00
2.1
2.9
—
—
—
0
0
19
190
1.00
-0.00
1.4
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.6
—
4.39
—
0
9
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
9
98
0.92
-0.00
3.6
4.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
37.13
—
0
7
21
210
1.00
-0.00
2.9
3.5
15.55
25.32
mu/l
1.97
21
203
0
5
0.00
-0.00
0.0
1.6
—
2923.32
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
20
200
1.00
-0.00
1.1
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
310.46
—
0
9
0
5
0.00
-0.00
0.0
3.0
—
1.78
—
0
5

Mortality – FinRegistry

Association

Association between endpoint H7_DIVERGSTRAB and mortality.

Females

Parameter HR [95% CI] p-value
H7_DIVERGSTRAB 1.402 [1.2, 1.63] < 0.001
Birth year 0.994 [0.99, 1.0] 0.189

During the follow-up period (1.1.1998 — 31.12.2019), 367 out of 5205 females with H7_DIVERGSTRAB died.

Males

Parameter HR [95% CI] p-value
H7_DIVERGSTRAB 1.47 [1.26, 1.71] < 0.001
Birth year 0.989 [0.98, 1.0] 0.019

During the follow-up period (1.1.1998 — 31.12.2019), 424 out of 4879 males with H7_DIVERGSTRAB died.

Mortality risk

Mortality risk for people of age

years, who have H7_DIVERGSTRAB.

N-year risk Females Males
1 0.126% 0.247%
5 0.883% 1.752%
10 1.992% 4.215%
15 3.76% 8.247%
20 6.617% 14.032%

Relationships between endpoints

Index endpoint: H7_DIVERGSTRAB – Divergent concomitant strabismus

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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