Other and unspecified haemorrhagic conditions

D3_HAEMORRHAGICNAS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D69.9
  • Hospital discharge: ICD-9 287[8-9]
  • Hospital discharge: ICD-8 2879
  • Hospital discharge: excluded ICD-8 28790
  • Cause of death: ICD-10 D69.9
  • Cause of death: ICD-9 287[8-9]
  • Cause of death: ICD-8 2879
  • Cause of death: excluded ICD-8 28790

2 out of 7 registries used, show all original rules.

609

4. Check minimum number of events

None

609

5. Include endpoints

None

609

6. Filter based on genotype QC (FinnGen only)

585

Control definitions (FinnGen only)

Control exclude
D3_COAGDEF_PURPUR_HAEMORRHAGIC

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
D69
Name in latin
Status haemorrhagicus non specificatus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4553 2524 1979
Only index persons 3723 2126 1597
Unadjusted period prevalence (%)
Whole population 0.06 0.07 0.06
Only index persons 0.07 0.08 0.06
Median age at first event (years)
Whole population 55.34 53.94 56.82
Only index persons 52.24 50.26 54.86

-FinnGen-

Key figures

All Female Male
Number of individuals 585 346 239
Unadjusted period prevalence (%) 0.12 0.12 0.11
Median age at first event (years) 55.65 49.87 64.02

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
609
Matched controls
6090
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D69.9
ICD-10 Finland
Haemorrhagic condition, unspecified
11288.0
307.7
521
*
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
125.2
205.0
104
10
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
+∞
63.7
60
*
28799
ICD-8 Finland
Purpura and other haemorrhagic conditions, Other and unspecified
+∞
56.1
53
*
D69.0
ICD-10 Finland
Allergic purpura
435.8
41.7
41
*
D68.0
ICD-10 Finland
Von Willebrand disease
+∞
35.8
34
*
XW000
NOMESCO Finland
Bone marrow biopsy
6.2
30.3
54
94
B02AA02
ATC
tranexamic acid; systemic
3.3
29.8
134
478
WW500
NOMESCO Finland
Blood transfusion
5.8
28.4
54
100
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.4
26.7
108
359
R50.9
ICD-10 Finland
Fever, unspecified
3.0
25.2
136
536
D68.9
ICD-10 Finland
Coagulation defect, unspecified
249.4
23.8
24
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.5
22.3
85
271
R4110
NOMESCO Finland
Physiotherapy
2.4
21.9
208
1077
ZX120
NOMESCO Finland
Intravenous
3.3
21.3
89
300
H02AB07
ATC
prednisone; oral
2.9
21.1
119
477
129
Kela drug reimbursment
Idiopathic thrombocytopaenia or granulocytopenia
+∞
21.0
20
*
ZXD05
NOMESCO Finland
Urgent procedure
2.3
20.9
227
1242
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.1
20.7
60
158
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.3
20.6
86
290
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
20.5
309
1929
L04AX01
ATC
azathioprine; systemic
5.0
19.7
44
94
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
19.3
111
448
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
18.9
162
794
D64.9
ICD-10 Finland
Anaemia, unspecified
3.0
18.7
93
347
H02AB06
ATC
prednisolone; systemic
2.1
18.3
315
2043
C03CA01
ATC
furosemide; systemic
2.2
18.2
218
1228
ZXE00
NOMESCO Finland
One hour or less
2.1
18.1
271
1664
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
17.4
205
1144
D69.4
ICD-10 Finland
Other primary thrombocytopenia
+∞
16.7
16
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.5
16.5
119
536
N02AX02
ATC
tramadol; systemic, rectal
2.0
16.5
285
1830
A02BC02
ATC
pantoprazole; systemic
2.1
16.4
426
3167
ZXE20
NOMESCO Finland
More than three and less than five hours
2.6
16.4
107
459
D68.8
ICD-10 Finland
Other specified coagulation defects
39.2
15.5
19
5
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.4
14.9
57
181
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
14.8
241
1499
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.3
14.7
134
667
2879X
ICD-9 Finland
Purpura and other haemorrhagic conditions, Unspecified haemorrhagic conditions
+∞
14.6
14
*
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
37.0
14.5
18
5
Z3231
NOMESCO Finland
Registered nurse
2.1
14.4
192
1109
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.2
14.0
153
819
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.3
14.0
56
183
Z3226
NOMESCO Finland
Physiotherapist
2.2
13.9
134
682
28798
ICD-8 Finland
Purpura and other haemorrhagic conditions, Purpura et status haemorrhagicus alius
+∞
13.6
13
*
D69.1
ICD-10 Finland
Qualitative platelet defects
+∞
13.6
13
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
13.3
249
1611
Z2221
NOMESCO Finland
Medical doctor
2.0
13.1
189
1118
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
4.7
13.0
30
66
B01AA03
ATC
warfarin; systemic
2.2
12.9
133
694
I50.9
ICD-10 Finland
Heart failure, unspecified
2.3
12.9
109
524
N18.8
ICD-10 Finland
Other chronic renal failure
5.4
12.6
25
48
28719
ICD-8 Finland
Purpura and other haemorrhagic conditions, Thrombocytopenia NUD
+∞
12.5
12
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.9
12.3
214
1344
A46
ICD-10 Finland
Erysipelas
2.3
12.2
102
487
M05BA04
ATC
alendronic acid; oral
2.8
12.1
66
257
L04AA06
ATC
mycophenolic acid; systemic
8.9
12.1
25
29
UJF32
NOMESCO Finland
Coloscopy
2.0
12.0
167
971
D07AB08
ATC
desonide; topical
2.5
12.0
83
364
C07AB07
ATC
bisoprolol; oral
1.8
11.9
301
2121
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
11.8
236
1545
TK800
NOMESCO Finland
Hemodialysis
5.3
11.8
24
47
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
11.7
170
1003
D69.8
ICD-10 Finland
Other specified haemorrhagic conditions
66.3
11.6
13
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
3.6
11.6
39
114
126
Kela drug reimbursment
Chronic coagulation defects
+∞
11.5
11
*
C03DA01
ATC
spironolactone; oral
2.4
11.5
86
391
WZC00
NOMESCO Finland
Treatment plan or consultation
1.8
11.2
222
1444
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
11.1
168
1003
R04.0
ICD-10 Finland
Epistaxis
2.8
11.0
59
228
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
10.9
125
675
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
5.0
10.8
23
47
J01MA12
ATC
levofloxacin; systemic
2.0
10.5
124
676
H02AB04
ATC
methylprednisolone; systemic
2.2
10.5
96
474
M04AA01
ATC
allopurinol; systemic
2.3
10.4
87
414
P01AB01
ATC
metronidazole; oral, rectal
1.8
10.4
250
1716
B01AB05
ATC
enoxaparin; parenteral
1.8
10.3
195
1246
JN3AD
NOMESCO Finland
Abdominal CT examination
2.4
10.2
78
358
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.1
10.0
42
141
K92.1
ICD-10 Finland
Melaena
3.0
10.0
45
158
R23.3
ICD-10 Finland
Spontaneous ecchymoses
4.8
9.8
22
47
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.7
9.8
56
224
J01FF01
ATC
clindamycin; systemic
1.8
9.7
169
1050
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.6
9.7
57
231
D69
ICD-10 Finland
Purpura and other haemorrhagic conditions
55.9
9.7
11
*
KA1AE
NOMESCO Finland
Kidney ultrasound examination
4.4
9.7
24
56
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.7
9.6
22
48
XF400
NOMESCO Finland
ECG with 12 standard connections
2.1
9.5
104
551
B03BA03
ATC
hydroxocobalamin; parenteral
2.9
9.5
44
157
AA1AD
NOMESCO Finland
CT of head and brain
1.8
9.5
165
1024
N08.2*D69.0
ICD-10 Finland
Glomerular disorders in Henoch(-Schönlein) purpura
+∞
9.4
9
*
2873A
ICD-9 Finland
Purpura and other haemorrhagic conditions, Primary thrombocytopenia[PURPURA THROMBOCYTOPENICA IDIOPATHICA (ITP)]
+∞
9.4
9
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.3
9.4
71
324
R06AE07
ATC
cetirizine; oral
1.7
9.4
257
1818
WX002
NOMESCO Finland
Sedation and analgesia
2.0
9.3
121
681
Z2446
NOMESCO Finland
Social worker
2.7
9.3
53
211
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.8
9.3
46
170
J01DB01
ATC
cefalexin; oral
1.9
9.1
497
4240
L04AA01
ATC
[U] ciclosporin
10.3
9.1
17
17
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
10.3
9.1
17
17
6BA02, ,
NOMESCO Finland
37.3
9.0
11
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.1
9.0
37
123
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
9.0
137
813
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.7
8.9
28
78
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.2
8.7
74
354
JN4AD
NOMESCO Finland
Body CT examination
2.4
8.7
63
282
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.5
8.6
30
90
R06.0
ICD-10 Finland
Dyspnoea
1.8
8.5
169
1086
D69.5
ICD-10 Finland
Secondary thrombocytopenia
91.3
8.4
9
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.6
8.4
49
198
D68.3
ICD-10 Finland
Haemorrhagic disorder due to circulating anticoagulants
+∞
8.3
8
*
R31
ICD-10 Finland
Unspecified haematuria
2.2
8.3
72
347
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
8.3
171
1109
L04AD01
ATC
ciclosporin; systemic
6.6
8.2
20
31
JMA10
NOMESCO Finland
Transabdominal total splenectomy
14.7
8.2
13
9
127
Kela drug reimbursment
Transplant complication
7.7
8.2
18
24
L95.8
ICD-10 Finland
Other vasculitis limited to skin
33.8
8.1
10
*
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.7
7.9
25
70
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.7
7.9
177
1174
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.7
7.8
41
157
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.0
7.8
35
123
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.9
7.7
35
124
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.3
7.6
56
252
D69.2
ICD-10 Finland
Other nonthrombocytopenic purpura
25.4
7.6
10
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
7.6
309
2379
UKC02
NOMESCO Finland
Cystoscopy
1.9
7.6
97
542
N03AX16
ATC
[U] pregabalin
1.8
7.5
137
855
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
4.3
7.5
19
45
S20.2
ICD-10 Finland
Contusion of thorax
2.8
7.4
36
132
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.1
7.4
30
99
E0000UV, ,
ATC
1.6
7.4
245
1791
I34.1
ICD-10 Finland
Mitral (valve) prolapse
3.6
7.3
24
69
A41.9
ICD-10 Finland
Sepsis, unspecified
3.3
7.3
27
84
A11CC03
ATC
alfacalcidol; systemic
3.9
7.3
21
55
2878X
ICD-9 Finland
Purpura and other haemorrhagic conditions, Other specified haemorrhagic conditions
+∞
7.3
7
*
205
Kela drug reimbursment
Chronic hypertension
1.7
7.3
154
1002
JN4BD
NOMESCO Finland
Extensive body CT
2.1
7.2
67
332
D70.89
ICD-10 Finland
Neutropenic splenomegaly
7.4
7.2
16
22
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
7.2
126
777
XLA10, ,
NOMESCO Finland
3.1
7.2
30
101
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.8
7.1
35
129
TPH07
NOMESCO Finland
Cathetrisation of artery
2.1
7.1
71
362
L03AA02
ATC
filgrastim; parenteral
3.7
7.1
22
61
J01DA01
ATC
[U] cefalexin
1.6
7.1
361
2911
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
6.9
107
634
WW200
NOMESCO Finland
Immunization
3.9
6.9
20
53
C08CA01
ATC
amlodipine; oral
1.6
6.8
215
1546
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.0
6.8
80
433
R1240
NOMESCO Finland
Social assessment of need and possibilities of rehabilitation
9.5
6.8
13
14
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
40.5
6.8
8
*
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
16.9
6.8
10
6
ZXA05
NOMESCO Finland
Left side
1.7
6.7
146
955
I35.0
ICD-10 Finland
Aortic (valve) stenosis
2.5
6.7
42
176
R60.9
ICD-10 Finland
Oedema, unspecified
2.6
6.7
38
152
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.8
6.6
32
117
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.5
6.6
43
183
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.3
6.6
50
228
TQW80
NOMESCO Finland
Local dermatologic skincare
3.9
6.6
19
50
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.2
6.5
56
269
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
70.6
6.4
7
*
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
6.4
112
688
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
6.4
406
3404
S97
ICPC
Chronic ulcer skin
2.4
6.4
43
186
J01MA02
ATC
ciprofloxacin; systemic
1.6
6.4
224
1646
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.0
6.4
69
363
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
8.3
6.4
13
16
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
6.3
119
747
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.9
6.3
77
423
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
6.3
254
1927
B02BX05
ATC
eltrombopag; oral
+∞
6.3
6
*
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
7.1
6.2
14
20
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
27.0
6.2
8
*
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
2.7
6.2
33
127
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
6.2
113
702
J47
ICD-10 Finland
Bronchiectasis
4.0
6.2
17
43
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.4
6.1
40
171
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
6.1
113
706
B01AB10
ATC
tinzaparin; parenteral
2.1
6.1
62
319
R79.9
ICD-10 Finland
Abnormal finding of blood chemistry, unspecified
10.2
6.1
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
199
696
3.76
47.76
3.6
2.1
30.93
29.61
s
1.84
194
678
86
168
5.80
43.12
3.0
2.2
20.51
21.43
s
1.02
79
153
175
710
3.06
31.43
4.1
3.3
0.80
0.82
mmol/l
0.80
168
675
168
720
2.84
26.82
3.3
2.4
11.41
12.99
umol/l
2.18
160
669
134
513
3.07
26.20
3.9
2.5
1.82
1.72
%
0.55
125
464
151
618
2.92
26.20
3.4
2.5
20.77
22.09
%
0.59
142
532
372
2374
2.46
25.21
10.4
5.3
0.61
0.57
e9/l
1.50
330
2060
379
2450
2.45
24.78
10.6
5.3
1.77
1.92
e9/l
1.19
340
2180
372
2385
2.44
24.78
10.4
5.3
0.04
0.04
e9/l
0.02
330
2070
348
2182
2.39
24.15
10.5
5.4
0.66
0.66
%
0.08
332
2034
410
2775
2.46
23.74
14.8
8.4
4.12
4.09
e9/l
0.08
364
2428
355
2256
2.38
23.74
10.5
5.4
2.63
2.89
%
1.31
340
2109
356
2266
2.37
23.70
10.7
5.7
8.96
8.55
%
1.61
341
2124
153
662
2.75
23.68
3.4
2.4
2.28
2.35
g/l
0.80
148
618
40
66
6.42
23.57
1.7
1.3
—
—
—
0
0
362
2328
2.37
23.43
10.5
5.5
26.51
27.88
%
1.47
345
2187
377
2475
2.37
23.15
10.7
5.7
0.18
0.19
e9/l
0.98
339
2185
238
1314
2.33
21.57
4.0
3.0
0.63
0.42
e6/l
0.54
192
983
68
192
3.86
21.32
1.8
1.8
1.59
1.47
g/l
0.36
54
171
347
2248
2.26
21.30
11.2
5.8
—
—
—
0
0
96
343
3.14
20.88
4.5
2.6
10.75
10.43
g/l
0.28
88
309
232
1283
2.31
20.79
3.9
3.0
—
—
—
0
0
351
2299
2.24
20.78
10.3
5.3
58.64
57.24
%
1.34
335
2162
282
1713
2.20
19.88
5.2
3.6
106.87
108.32
e6/l
0.01
218
1195
250
1449
2.23
19.79
4.3
3.2
70.57
110.20
e6/l
0.33
203
1103
98
367
2.99
19.59
3.2
2.2
74.35
68.49
e9/l
0.89
72
301
188
971
2.35
19.56
3.9
2.9
506.03
550.98
mosm/kgh2o
1.93
170
829
364
2460
2.19
19.40
8.5
5.7
11.63
11.18
umol/l
0.25
348
2328
139
633
2.55
19.02
1.6
1.3
840.00
455.89
titre
0.90
34
141
97
373
2.90
18.44
3.8
2.5
65.78
66.59
g/l
0.43
90
340
327
2157
2.11
18.09
15.7
8.7
0.00
0.00
e9/l
0.15
269
1761
80
281
3.13
17.81
2.4
1.5
1.25
1.42
g/l
0.26
72
257
186
995
2.25
17.53
3.2
2.7
6.55
5.96
e6/l
0.18
176
891
219
1259
2.15
17.19
6.1
3.9
—
—
—
0
0
59
176
3.60
17.02
1.3
1.2
0.27
2.49
u/ml
—
6
11
327
2192
2.06
16.93
4.1
2.7
170.76
109.01
ug/l
2.48
311
2036
212
1211
2.15
16.85
8.5
6.4
—
—
—
0
0
212
1212
2.15
16.81
3.3
2.2
3.96
3.06
mg/l
2.94
186
1048
306
2019
2.04
16.37
7.5
4.4
35.15
35.66
g/l
0.94
287
1884
82
308
2.92
16.19
3.6
2.1
—
—
—
0
0
155
792
2.28
16.15
3.1
2.6
1.29
0.99
e6/l
0.59
85
435
249
1543
2.04
15.68
3.3
2.2
—
—
—
0
0
124
591
2.38
15.09
8.6
5.5
1.09
1.06
mmol/l
0.61
119
546
146
751
2.24
14.84
3.5
2.8
3.39
2.36
e6/l
0.47
76
396
319
2188
1.96
14.75
26.5
13.8
1.35
1.25
inr
1.11
110
649
334
2340
1.95
14.37
10.9
6.2
1.21
1.22
mmol/l
1.24
291
1984
24
40
6.21
13.95
1.3
1.1
—
—
—
0
0
200
1187
2.02
13.87
3.5
2.6
7365.23
8228.65
umol/l
0.07
181
1045
225
1399
1.96
13.60
6.5
3.8
7.39
7.40
ph
0.32
50
265
186
1083
2.03
13.55
2.6
1.7
1.15
1.13
mg/l
0.04
153
825
307
2121
1.90
13.47
9.4
5.6
1.21
1.22
mmol/l
1.15
293
1925
84
354
2.59
13.23
5.6
4.1
0.35
0.14
%
0.82
34
115
96
432
2.45
13.17
5.5
4.2
1.78
1.91
mmol/l
0.12
82
354
79
330
2.60
12.65
5.8
4.0
0.84
0.60
%
0.41
32
110
459
3663
2.03
12.60
12.4
6.9
80.97
78.94
u/l
0.42
446
3432
86
376
2.50
12.53
5.6
4.0
1.29
0.95
%
0.55
36
138
213
1333
1.92
12.41
3.4
3.1
2212.26
1355.66
ng/l
1.16
183
1127
109
535
2.26
12.23
4.1
2.6
6.48
7.74
umol/l
0.45
92
466
78
330
2.56
12.16
5.8
4.1
0.03
0.12
%
0.43
29
93
92
430
2.34
11.54
3.0
2.4
29.81
32.65
u/l
0.64
79
356
35
96
3.81
11.39
2.8
3.9
—
—
—
0
0
109
551
2.19
11.33
2.1
1.6
—
—
—
0
0
276
1915
1.81
11.33
4.4
3.4
5.95
5.82
ph
0.31
21
149
21
38
5.69
11.24
1.1
1.1
—
—
—
0
0
326
2396
1.78
10.84
5.2
3.7
0.00
0.01
estimate
0.50
69
436
322
2363
1.77
10.72
5.1
3.7
0.00
0.00
estimate
0.50
77
483
81
372
2.36
10.55
11.1
8.9
—
—
—
0
0
321
2364
1.76
10.46
6.9
5.0
0.00
0.00
estimate
0.50
72
450
29
74
4.06
10.42
1.4
1.2
3.20
4.31
u/ml
—
10
29
23
49
4.84
10.32
1.7
1.2
—
—
—
0
0
34
98
3.62
10.31
1.6
1.6
—
—
—
0
0
41
134
3.21
10.25
4.2
3.4
41.88
107.71
mg/l
0.80
32
111
41
134
3.21
10.25
4.2
3.4
36.96
32.69
mg/l
0.30
32
111
48
173
2.93
10.16
1.8
1.8
0.48
2.68
ug/l
0.77
43
155
23
50
4.74
10.08
2.4
1.5
33.13
32.68
pg
0.17
23
50
186
1179
1.83
10.04
3.4
2.1
—
—
—
0
0
218
1455
1.78
9.87
3.4
2.5
56.05
61.78
u/l
0.83
207
1359
40
132
3.17
9.84
4.3
3.4
1.11
2.26
ratio
—
7
15
120
663
2.01
9.78
2.8
1.9
—
—
—
0
0
160
984
1.85
9.44
1.9
1.4
2.66
2.35
g/l
1.05
100
601
9
0
+∞
9.40
1.4
0.0
38.92
—
s
—
9
0
39
131
3.11
9.33
1.3
1.2
64.06
2.65
u/ml
—
5
17
87
435
2.17
9.22
3.1
2.4
0.21
0.22
g/l
0.05
81
403
170
1072
1.81
9.22
4.6
3.6
—
—
—
0
0
307
2295
1.68
8.97
3.6
2.5
—
—
—
0
0
400
3212
1.71
8.88
6.2
4.4
735.89
2947.22
e6/l
—
9
55
71
333
2.28
8.78
1.7
1.4
—
—
—
0
0
224
1548
1.71
8.74
4.3
2.9
31.23
30.65
u/l
0.08
214
1478
359
2808
1.68
8.73
7.8
4.6
6.65
6.66
mmol/l
0.06
345
2601
101
546
2.02
8.70
1.9
1.6
—
—
—
0
0
80
409
2.10
7.99
9.8
7.3
1.28
1.37
mmol/l
0.49
80
399
51
216
2.49
7.92
3.0
3.2
0.61
0.67
%
0.71
51
216
110
633
1.90
7.87
1.3
1.2
—
—
—
0
0
411
3377
1.67
7.85
6.5
4.2
—
—
—
0
0
19
44
4.43
7.73
2.0
2.3
1.93
1.64
g/24h
—
9
23
263
1942
1.62
7.70
2.9
2.3
74.68
76.96
nmol/l
0.65
249
1731
212
1484
1.66
7.67
4.2
3.0
—
—
—
0
0
248
1812
1.62
7.54
4.9
3.6
55.79
37.39
ng/l
0.36
170
1237
224
1598
1.64
7.49
4.4
3.2
2.34
2.35
mmol/l
0.31
205
1414
17
39
4.46
7.00
1.6
1.0
—
—
—
0
0
21
57
3.78
6.97
2.4
1.6
—
—
—
0
0
201
1418
1.62
6.92
2.9
2.0
266.15
305.76
u/l
0.14
196
1336
253
1888
1.58
6.87
2.4
2.0
94.50
95.32
pmol/l
0.10
165
955
29
99
3.03
6.78
4.4
2.7
35.31
33.71
umol/l
0.14
29
87
35
133
2.73
6.76
3.4
3.2
—
—
—
0
0
102
607
1.82
6.51
1.4
1.3
—
—
—
0
0
30
108
2.87
6.41
1.4
1.2
47.35
27.15
u/ml
—
8
12
17
42
4.14
6.39
1.2
1.2
—
—
—
0
0
13
16
8.28
6.36
2.7
2.6
738.23
541.31
u/ml
0.65
13
16
99
590
1.81
6.28
2.6
2.3
150.73
118.18
ug/g
0.34
76
461
163
1123
1.62
6.06
1.8
1.5
20.18
20.81
nmol/l
0.18
140
958
18
49
3.75
5.96
1.7
1.3
—
—
—
0
0
10
9
11.27
5.81
1.6
2.6
—
—
—
0
0
21
65
3.31
5.77
1.0
1.1
—
—
—
0
0
421
3598
1.55
5.76
6.6
3.9
14.73
11.65
mm/h
3.10
401
3314
16
41
3.98
5.74
1.6
2.4
—
—
—
0
0
393
3318
1.52
5.61
4.3
3.7
—
—
—
0
0
122
796
1.67
5.59
1.4
1.3
29.57
33.13
iu/ml
0.15
43
264
16
42
3.89
5.57
1.2
1.0
—
—
—
0
0
25
89
2.89
5.47
1.6
1.3
215.64
224.24
u/ml
0.06
14
50
43
200
2.24
5.46
2.2
2.3
5570.48
3133.96
u/l
0.32
18
82
118
771
1.66
5.36
2.0
1.7
—
—
—
0
0
23
80
2.95
5.24
1.8
1.6
—
—
—
0
0
53
274
2.02
5.15
1.6
1.3
—
—
—
0
0
19
60
3.24
5.08
1.0
1.0
—
—
—
0
0
25
93
2.76
5.07
3.1
3.3
2.01
2.68
mmol/l
0.70
19
55
36
161
2.31
5.02
1.4
1.3
—
—
—
0
0
128
868
1.60
4.99
1.9
1.7
1115.85
1178.14
nmol/l
0.32
100
663
21
73
2.94
4.81
3.2
3.5
59.84
62.96
%
0.23
21
73
175
1287
1.50
4.73
6.0
4.0
0.00
0.00
estimate
0.50
68
439
24
91
2.70
4.71
2.3
3.1
—
—
—
0
0
131
907
1.57
4.66
4.2
3.8
1508.42
340.48
ng/l
0.54
103
682
130
899
1.57
4.65
3.6
2.9
2.45
2.45
mmol/l
0.03
114
788
24
92
2.67
4.61
3.8
4.1
—
—
—
0
0
84
526
1.69
4.47
1.5
1.3
—
—
—
0
0
15
45
3.39
4.35
1.6
1.2
—
—
—
0
0
534
4927
1.68
4.30
29.0
15.5
139.34
139.66
mmol/l
2.31
522
4784
82
517
1.68
4.25
10.4
7.3
1.37
1.12
mmol/l
0.23
61
417
20
73
2.80
4.22
1.4
1.5
—
—
—
0
0
20
73
2.80
4.22
1.5
1.2
—
—
—
0
0
64
378
1.77
4.18
5.4
3.4
—
—
—
0
0
36
175
2.12
4.14
4.2
3.5
1.09
1.29
mmol/l
1.45
36
168
534
4938
1.66
4.13
29.7
15.6
3.96
3.97
mmol/l
0.59
521
4786
470
4228
1.49
4.09
31.4
16.0
14.69
14.90
%
0.43
464
4174
67
404
1.74
4.08
1.5
1.4
—
—
—
0
0
22
87
2.59
4.01
2.4
1.5
—
—
—
0
0
371
3205
1.40
3.96
4.2
3.0
51.09
45.02
u/l
1.04
348
2999
526
4860
1.60
3.91
27.9
13.4
23.76
22.82
mg/l
0.26
468
3850
52
296
1.83
3.85
1.3
1.2
287.27
222.57
u/ml
0.13
45
266
14
38
3.75
3.81
3.6
3.4
—
—
—
0
0
6
5
12.10
3.77
1.2
1.0
—
—
—
0
0
44
241
1.89
3.67
1.9
2.5
—
—
—
0
0
35
177
2.04
3.66
5.9
4.2
—
—
—
0
0
16
56
2.91
3.65
1.3
1.1
1.42
1.45
g/l
0.13
16
50
15
51
2.99
3.59
3.2
2.5
—
—
—
0
0
67
419
1.67
3.59
11.6
8.1
113.25
121.19
g/l
2.54
67
411
14
46
3.09
3.55
1.2
1.4
—
—
—
0
0
42
230
1.89
3.52
4.9
3.6
24.88
25.09
mmol/l
0.15
42
225
129
942
1.47
3.52
2.4
1.9
—
—
—
0
0
65
406
1.67
3.50
6.0
3.8
—
—
—
0
0
108
764
1.50
3.44
1.3
1.3
4.22
9.31
u/ml
1.22
40
307
20
82
2.49
3.41
2.4
1.5
107.40
114.57
u/ml
—
5
14
13
42
3.14
3.39
1.2
1.5
76.00
65.73
%
—
5
33
48
278
1.79
3.38
7.8
6.4
23.89
24.63
mmol/l
0.70
48
265
36
190
1.95
3.37
1.1
1.2
—
—
—
0
0
11
28
3.98
3.30
4.1
3.6
—
—
—
0
0
33
171
1.98
3.25
1.5
1.7
—
—
—
0
0
45
259
1.80
3.24
4.3
3.0
0.35
0.20
e6/l
0.61
45
251
7
11
6.42
3.19
1.1
1.0
—
—
—
0
0
7
11
6.42
3.19
1.0
1.0
—
—
—
0
0
14
50
2.84
3.10
1.3
1.7
—
—
—
0
0
14
50
2.84
3.10
1.7
1.3
42.12
53.04
mu/l
0.15
14
45
171
1348
1.37
3.00
5.0
3.3
—
—
—
0
0
21
94
2.28
2.99
2.9
2.9
0.65
0.89
nmol/l
1.21
16
74
46
278
1.71
2.83
4.0
3.4
4.60
4.55
pmol/l
0.06
38
250
72
487
1.54
2.83
3.6
4.2
27.28
22.17
ug/l
0.10
61
410
48
295
1.68
2.78
4.9
4.1
—
—
—
0
0
20
91
2.24
2.76
2.1
2.4
—
—
—
0
0
7
14
5.04
2.73
1.6
1.6
—
—
—
0
0
233
1949
1.32
2.71
2.4
2.1
—
—
—
0
0
52
329
1.63
2.71
1.6
1.4
—
—
—
0
0
8
19
4.25
2.68
1.9
1.7
—
—
—
0
0
10
30
3.37
2.61
4.1
6.1
10.17
11.95
%
—
10
30
56
366
1.58
2.57
2.4
3.2
338.98
226.28
ng/l
0.85
51
339
144
1132
1.36
2.54
1.3
1.3
1.73
2.06
u/ml
0.12
35
312
80
568
1.47
2.51
1.6
1.3
—
—
—
0
0
8
21
3.85
2.47
1.4
1.4
—
—
—
0
0
14
57
2.49
2.46
1.3
1.2
—
—
—
0
0
50
322
1.60
2.44
4.4
3.6
4.99
5.11
kpa
0.40
45
307
18
83
2.20
2.43
1.8
2.4
14.77
16.10
%
—
7
43
6
12
5.04
2.40
1.8
2.4
—
—
—
0
0
21
104
2.06
2.39
1.5
1.6
8167.69
20720.99
e6/l
1.05
13
76
5
8
6.29
2.37
7.2
3.9
—
—
—
0
0
5
8
6.29
2.37
1.6
2.3
—
—
—
0
0
7
17
4.15
2.36
2.6
3.6
—
—
—
0
0
11
39
2.85
2.35
1.1
1.3
—
—
—
0
0
57
385
1.53
2.28
1.2
1.1
—
—
—
0
0
6
13
4.65
2.27
3.8
2.2
—
—
—
0
0
6
13
4.65
2.27
2.2
2.3
51.17
87.87
ug/l
—
6
13
173
1426
1.30
2.17
3.7
3.1
7.24
7.44
mmol/l
0.23
148
1200
7
19
3.71
2.15
1.7
2.2
46.86
104.50
mg/l
—
7
14
6
14
4.32
2.15
3.5
6.8
23.83
25.16
mmol/l
—
6
14
12
49
2.48
2.11
1.0
1.0
—
—
—
0
0
48
319
1.55
2.08
4.4
3.6
7.39
7.41
ph
—
5
31
9
31
2.93
2.08
1.6
3.8
—
—
—
0
0
5
10
5.03
2.07
1.2
1.1
—
—
—
0
0
167
1378
1.29
2.07
4.6
3.8
20.80
8.56
mg/mmol
1.12
126
861
125
993
1.33
2.04
1.8
1.7
431.42
5875875.41
pmol/l
0.50
98
851
14
63
2.25
2.02
3.5
3.5
—
—
—
0
0
63
449
1.45
1.97
1.3
1.4
—
—
—
0
0
158
1302
1.29
1.97
3.9
3.2
780.36
254.19
mg/l
0.54
118
841
14
64
2.22
1.95
1.6
1.5
—
—
—
0
0
5
11
4.57
1.94
1.2
1.1
—
—
—
0
0
5
11
4.57
1.94
1.4
1.0
—
—
—
0
0
36
228
1.62
1.92
5.0
3.5
—
—
—
0
0
12
52
2.33
1.88
4.3
3.3
—
—
—
0
0
9
34
2.67
1.87
1.1
1.2
—
—
—
0
0
8
28
2.88
1.86
1.6
4.1
—
—
—
0
0
29
175
1.69
1.86
2.5
2.8
—
—
—
0
0
11
46
2.42
1.86
3.7
2.5
63.09
56.90
%
0.47
11
40
404
3725
1.25
1.86
4.8
3.9
14.71
14.67
pmol/l
0.11
379
3388
6
17
3.55
1.84
3.8
3.1
—
—
—
0
0
5
12
4.19
1.82
1.4
1.2
—
—
—
0
0
5
12
4.19
1.82
1.4
1.2
—
—
—
0
0
5
12
4.19
1.82
1.4
1.2
—
—
—
0
0
132
1077
1.29
1.77
5.4
4.0
1.02
1.02
kg/l
0.62
16
161
6
18
3.36
1.75
2.7
2.8
43383.33
34922.50
ug/l
—
6
18
46
318
1.48
1.70
1.2
1.2
—
—
—
0
0
27
165
1.67
1.67
3.1
3.5
0.21
0.32
g/l
0.38
14
62
17
90
1.91
1.66
4.4
2.6
—
—
—
0
0
23
135
1.73
1.64
1.2
1.4
14.04
10.03
u/l
0.66
18
106
20
113
1.80
1.62
1.7
1.2
—
—
—
0
0
12
56
2.17
1.62
1.2
1.1
—
—
—
0
0
535
5134
1.35
1.62
17.5
9.7
25.17
25.30
u/l
0.07
527
4954
5
14
3.59
1.62
1.6
1.4
—
—
—
0
0
5
14
3.59
1.62
1.0
1.0
—
—
—
0
0
26
159
1.66
1.61
1.2
1.2
—
—
—
0
0
7
26
2.71
1.58
2.6
2.1
—
—
—
0
0
5
15
3.35
1.52
1.2
1.0
—
—
—
0
0
22
131
1.70
1.51
5.9
4.4
—
—
—
0
0
11
51
2.18
1.51
1.5
1.2
—
—
—
0
0
6
21
2.87
1.51
1.2
1.1
634.25
115.61
iu/ml
—
6
21
33
219
1.54
1.49
16.3
10.6
—
—
—
0
0
45
319
1.44
1.49
2.4
2.7
4.28
5.86
e9/l
0.63
40
266
10
45
2.24
1.47
1.1
1.3
489938.00
26743.33
e6/l
—
5
24
35
237
1.51
1.45
5.1
3.4
—
—
—
0
0
5
16
3.14
1.44
6.8
3.5
55.80
52.38
%
—
5
16
6
22
2.74
1.43
1.3
1.0
—
—
—
0
0
473
4493
1.24
1.39
5.7
4.6
1.87
2.14
mu/l
0.50
446
4112
9
41
2.21
1.37
2.1
2.2
1065.56
560.38
ml
—
9
24
18
106
1.72
1.30
3.3
2.5
—
—
—
0
0
461
4382
1.21
1.26
6.6
5.6
39.96
39.73
mmol/mol
0.20
424
4090
161
1396
1.21
1.25
4.3
3.8
—
—
—
0
0
6
25
2.41
1.24
1.0
1.6
—
—
—
0
0
6
25
2.41
1.24
1.3
1.2
33.71
31.79
nmol/l
—
6
20
526
5075
1.27
1.21
24.6
12.5
—
—
—
0
0
14
79
1.79
1.17
1.4
1.1
—
16.12
—
0
5
20
126
1.61
1.16
2.3
1.7
5.07
6.33
iu/l
—
8
43
10
51
1.98
1.11
2.8
1.1
—
—
—
0
0
484
4642
1.21
1.10
5.0
4.4
5.95
5.91
mmol/l
0.31
444
4244
5
21
2.39
1.09
1.2
1.1
—
—
—
0
0
5
21
2.39
1.09
2.2
1.3
—
—
—
0
0
11
59
1.88
1.08
2.1
3.3
—
—
—
0
0
140
1223
1.19
1.00
1.5
1.6
1.56
1.36
mmol/l
1.58
117
1039
13
76
1.73
0.99
1.4
1.2
—
—
—
0
0
7
37
1.90
0.94
1.6
1.4
—
—
—
0
0
6
27
2.23
0.93
1.2
2.0
1.00
1.87
u/field
—
6
21
6
28
2.15
0.91
2.2
2.0
9.83
9.14
mmol/l
—
6
28
21
143
1.49
0.91
1.1
2.1
—
—
—
0
0
37
481
0.75
0.90
1.1
1.3
—
—
—
0
0
10
56
1.80
0.88
1.2
1.3
0.88
0.52
nmol/l
—
10
50
6
30
2.01
0.87
1.5
1.7
0.96
0.98
g/l
—
6
30
19
128
1.50
0.87
1.6
1.4
303.17
306.00
ug/g
—
6
75
488
4721
1.17
0.81
4.9
4.3
4.37
4.64
mmol/l
6.76
456
4390
0
26
0.00
0.78
0.0
1.0
—
247.56
—
0
16
468
4519
1.15
0.77
4.5
3.8
1.30
1.25
mmol/l
0.82
431
4162
553
5414
1.23
0.77
40.3
19.7
230.18
250.98
e9/l
6.96
546
5276
553
5414
1.23
0.77
40.9
19.8
39.04
39.99
%
3.63
536
5081
9
53
1.71
0.75
1.1
1.2
—
—
—
0
0
5
24
2.09
0.74
1.2
1.1
—
—
—
0
0
38
299
1.29
0.74
1.3
1.4
—
56.41
—
0
20
553
5417
1.23
0.74
40.3
19.7
4.35
4.48
e12/l
6.68
544
5263
553
5418
1.22
0.73
40.3
19.7
6.95
6.73
e9/l
1.38
545
5262
5
25
2.01
0.73
1.2
1.1
—
—
—
0
0
43
349
1.25
0.67
1.3
1.2
131.93
172.40
iu/ml
0.34
16
142
483
4690
1.14
0.67
4.7
4.2
1.37
1.48
mmol/l
7.65
449
4338
5
28
1.79
0.66
1.4
1.3
—
—
—
0
0
34
271
1.27
0.62
4.3
2.6
33.24
48.79
u/ml
0.47
34
257
8
49
1.64
0.62
1.1
1.3
—
—
—
0
0
8
50
1.61
0.61
1.6
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.2
—
6.90
—
0
21
493
4804
1.14
0.60
5.2
4.7
2.56
2.74
mmol/l
4.37
454
4444
0
23
0.00
0.58
0.0
1.1
—
—
—
0
0
8
54
1.49
0.57
1.4
1.4
25.24
21.16
ug/l
—
8
54
23
177
1.31
0.55
1.3
1.3
208.33
287.48
miu/ml
—
9
87
6
38
1.58
0.54
1.2
1.5
—
—
—
0
0
9
63
1.43
0.52
1.1
1.9
—
—
—
0
0
12
166
0.72
0.48
15.7
9.0
—
—
—
0
0
36
300
1.21
0.48
1.6
2.2
11.60
12.79
nmol/l
0.43
30
273
25
201
1.25
0.45
1.1
1.7
—
—
—
0
0
5
31
1.62
0.43
1.0
1.2
2.82
1.88
mmol/l
—
5
31
52
455
1.16
0.41
6.4
3.6
—
—
—
0
0
25
204
1.24
0.41
1.1
1.7
—
—
—
0
0
25
204
1.24
0.41
1.1
1.7
—
—
—
0
0
23
186
1.25
0.41
2.7
1.9
—
—
—
0
0
7
101
0.69
0.40
1.0
1.3
4.49
3.81
mmol/l
—
7
94
10
71
1.42
0.39
1.2
1.2
—
—
—
0
0
5
35
1.43
0.39
1.2
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
193.09
—
0
19
25
206
1.22
0.38
1.1
1.7
—
—
—
0
0
5
37
1.35
0.37
1.0
1.1
—
—
—
0
0
6
42
1.43
0.35
3.2
3.2
36.93
17.52
mg/l
—
6
32
21
254
0.82
0.34
1.5
1.7
—
—
—
0
0
17
136
1.26
0.34
1.4
1.2
—
—
—
0
0
13
101
1.29
0.32
1.2
2.0
—
—
—
0
0
146
1384
1.07
0.29
4.5
4.8
2.30
2.49
ug/l
0.21
132
1244
58
534
1.10
0.24
2.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
22
192
1.15
0.21
1.1
1.7
—
—
—
0
0
6
51
1.18
0.19
1.3
2.3
—
—
—
0
0
12
100
1.20
0.18
1.9
1.1
—
—
—
0
0
59
552
1.08
0.18
2.1
1.7
—
—
—
0
0
8
71
1.13
0.16
2.6
2.7
3.96
4.06
mmol/l
—
8
71
8
71
1.13
0.16
2.6
2.7
104.50
105.55
mmol/l
—
8
71
8
71
1.13
0.16
2.6
2.7
—
—
—
0
0
11
92
1.20
0.16
1.0
1.1
0.07
2.96
u/ml
—
6
52
6
79
0.76
0.15
1.0
1.1
—
—
—
0
0
34
314
1.09
0.14
2.8
3.0
—
—
—
0
0
14
125
1.12
0.10
1.8
1.5
—
—
—
0
0
18
164
1.10
0.10
1.1
1.7
—
—
—
0
0
167
1700
0.98
0.08
3.2
2.8
—
—
—
0
0
13
117
1.11
0.08
1.1
1.8
44.77
40.04
nmol/l
0.40
13
112
53
512
1.04
0.06
1.4
1.4
—
—
—
0
0
139
1367
1.02
0.06
1.7
1.5
—
—
—
0
0
10
110
0.91
0.05
1.1
1.4
600.10
434.63
mg/l
—
10
105
22
209
1.05
0.04
1.1
1.1
—
—
—
0
0
13
122
1.07
0.02
1.8
1.4
—
—
—
0
0
13
122
1.07
0.02
1.8
1.4
—
—
—
0
0
12
113
1.06
0.02
1.0
1.1
—
—
—
0
0
21
203
1.04
0.01
1.2
1.1
—
—
—
0
0
79
798
0.99
0.01
3.0
3.0
0.69
0.80
ug/l
0.87
54
516
12
126
0.95
0.00
1.1
1.3
—
—
—
0
0
7
79
0.88
0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
30
300
1.00
-0.00
1.5
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
4.16
—
0
7
0
8
0.00
-0.00
0.0
1.4
—
41.13
—
0
8
7
72
0.97
-0.00
1.9
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
7
75
0.93
-0.00
2.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
91
0.99
-0.00
1.1
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
3693.60
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
59
0.85
-0.00
1.4
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
1.32
—
0
6
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint D3_HAEMORRHAGICNAS and mortality.

Females

Parameter HR [95% CI] p-value
D3_HAEMORRHAGICNAS 2.577 [2.13, 3.11] < 0.001
Birth year 0.996 [0.99, 1.0] 0.377

During the follow-up period (1.1.1998 — 31.12.2019), 542 out of 1833 females with D3_HAEMORRHAGICNAS died.

Males

Parameter HR [95% CI] p-value
D3_HAEMORRHAGICNAS 2.773 [2.18, 3.53] < 0.001
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 549 out of 1402 males with D3_HAEMORRHAGICNAS died.

Mortality risk

Mortality risk for people of age

years, who have D3_HAEMORRHAGICNAS.

N-year risk Females Males
1 0.304% 0.488%
5 1.55% 3.02%
10 3.838% 7.322%
15 6.969% 14.394%
20 12.299% 23.449%

Relationships between endpoints

Index endpoint: D3_HAEMORRHAGICNAS – Other and unspecified haemorrhagic conditions

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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