impetigo: A pyoderma consisting of three forms of skin lesions having either a thick, adherent, recurrent, dirty yellow crust with an erythematous margin (common or superficial impetigo) or lessions which are superficial, thin-walled, and bullous as found in bullous impetigo. The lesions in bullous (staphylococcal) impetigo, which are always caused by S aureus, are superficial, thin-walled, and bullous.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1787 |
4. Check minimum number of eventsNone |
1787 |
5. Include endpointsNone |
1787 |
6. Filter based on genotype QC (FinnGen only) |
1787 |
Control definitions (FinnGen only)
- Control exclude
- L12_INFECT_SKIN
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L00-L08
- Name in latin
- Impetigo
Similar endpoints
↥List of similar endpoints to
Impetigo
based on the number of shared cases.
Similar with more cases:
- Infections of the skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 28301 | 13366 | 14843 |
| Only index persons | 20231 | 9754 | 10477 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.40 | 0.38 | 0.41 |
| Only index persons | 0.38 | 0.36 | 0.40 |
| Median age at first event (years) | |||
| Whole population | 10.66 | 11.12 | 10.05 |
| Only index persons | 15.69 | 15.96 | 15.43 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1787 | 1033 | 754 |
| Unadjusted period prevalence (%) | 0.34 | 0.35 | 0.33 |
| Median age at first event (years) | 23.24 | 24.08 | 22.08 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1601
- Matched controls
- 16011
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L01.0
ICD-10 Finland
Impetigo [any organism] [any site]
168.4
323.0
739
81
L01.1
ICD-10 Finland
Impetiginization of other dermatoses
248.7
302.9
303
15
68409
ICD-8 Finland
Impetigo, Unspecified
+∞
200.3
188
*
68408
ICD-8 Finland
Impetigo, Alia definita
+∞
181.8
171
*
6840A
ICD-9 Finland
Impetigo[IMPETIGO CONTAGIOSA]
+∞
115.0
109
*
L20.0
ICD-10 Finland
Besnier prurigo
4.9
93.8
347
856
E0000UV
ATC
NA
2.9
87.4
833
4349
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
20.6
81.9
124
65
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
3.7
70.2
349
1110
L01
ICD-10 Finland
Impetigo
12.5
68.2
126
109
D07BA04
ATC
hydrocortisone and antiseptics; topical
3.7
66.2
331
1052
L30.9
ICD-10 Finland
Dermatitis, unspecified
3.2
62.3
388
1452
D07AC01
ATC
betamethasone; topical
2.6
58.8
596
3011
E000001
ATC
NA
2.8
57.3
467
2073
D07AA02
ATC
hydrocortisone; topical
3.0
55.2
383
1529
D07AB08
ATC
desonide; topical
3.6
53.8
269
843
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
10.0
51.0
105
112
J01DB01
ATC
cefalexin; oral
2.6
47.9
1343
10717
E000002
ATC
NA
3.0
45.7
294
1100
J01FF01
ATC
clindamycin; systemic
2.4
41.8
440
2187
D07AB02
ATC
hydrocortisone butyrate; topical
2.3
41.6
482
2512
D07CC01
ATC
betamethasone and antibiotics; topical
3.0
41.6
270
1013
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.9
40.4
285
1127
TQW80
NOMESCO Finland
Local dermatologic skincare
8.2
39.7
91
117
6918B
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[ECZEMA ATOPICUM]
14.2
39.1
67
49
D07AC13
ATC
mometasone; topical
2.2
37.7
476
2563
N05BB01
ATC
hydroxyzine; systemic
3.8
37.0
167
474
A46
ICD-10 Finland
Erysipelas
3.3
35.7
198
660
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
4.6
34.5
126
293
D11AH01
ATC
tacrolimus; topical
10.0
34.0
69
72
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.5
33.0
165
509
H02AB06
ATC
prednisolone; systemic
1.9
31.3
668
4369
R06AE07
ATC
cetirizine; oral
1.9
30.9
732
4961
L30.3
ICD-10 Finland
Infective dermatitis
5.2
29.8
95
191
70708
ICD-8 Finland
Chronic ulcer of skin, Aliud definitum
+∞
29.2
28
*
E000003
ATC
NA
3.9
28.4
124
341
D11AX14
ATC
[U] tacrolimus; topical
24.1
28.4
40
17
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.7
28.4
211
851
J01DA01
ATC
[U] cefalexin; systemic
1.8
28.2
939
7045
D07BC01
ATC
betamethasone and antiseptics; topical
2.7
27.7
203
810
XQ802
NOMESCO Finland
Epicutan test
4.3
27.6
106
259
J05AB01
ATC
aciclovir; systemic
2.2
26.9
324
1671
E000006
ATC
NA
3.3
26.8
145
473
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
7.4
26.7
64
89
J01DA09
ATC
[U] cefadroxil; inhalant, oral
2.0
26.0
440
2601
D02AE01
ATC
carbamide; topical
3.2
26.0
145
482
L08.0
ICD-10 Finland
Pyoderma
13.2
25.7
45
35
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
2.6
23.8
193
814
D07AD01
ATC
clobetasol; topical
2.3
21.3
220
1046
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
20.9
543
3655
H03.8*L01.0
ICD-10 Finland
Involvement of eyelid in impetigo
+∞
20.9
20
*
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.4
20.4
183
812
R06AX27
ATC
desloratadine; oral
1.8
20.3
487
3193
XQ800
NOMESCO Finland
Prick test
2.4
20.1
175
765
D02AX
ATC
Other emollients and protectives
3.2
19.4
104
338
L20
ICD-10 Finland
Atopic dermatitis
3.6
19.2
90
263
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.9
18.7
298
1693
S87
ICPC
Dermatitis/atopic eczema
4.0
18.7
76
197
D11AH02
ATC
pimecrolimus; topical
12.5
18.1
32
26
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
7.5
18.0
42
57
XQ848
NOMESCO Finland
Dermatological photography
4.9
17.1
56
118
S29
ICPC
Skin symptom/complaint other
1.9
16.4
250
1394
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
5.8
16.4
46
81
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
16.2
268
1536
D09AB01
ATC
zinc bandage without supplements; topical
5.3
15.9
48
92
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
5.0
15.9
51
105
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.3
15.9
148
667
B00.10
ICD-10 Finland
Herpes simplex facialis
9.3
15.7
32
35
68400
ICD-8 Finland
Impetigo, Pemphigus neonatorum
+∞
15.6
15
*
E000004
ATC
NA
5.6
15.6
45
82
J05AB11
ATC
valaciclovir; oral
2.1
15.4
182
915
D07XB05
ATC
dexamethasone, combinations; topical
4.5
15.0
53
121
E000007
ATC
NA
2.5
14.7
116
481
H02AB07
ATC
prednisone; oral
2.1
14.6
177
899
H02AB04
ATC
methylprednisolone; systemic
2.0
14.2
190
1006
S76
ICPC
Skin infection other
3.0
14.0
82
285
L30.0
ICD-10 Finland
Nummular dermatitis
3.8
13.8
58
157
L05.9
ICD-10 Finland
Pilonidal cyst without abscess
75.8
13.6
15
*
395
Kela drug reimbursment
Dupilumab
+∞
13.6
13
*
J01MA12
ATC
levofloxacin; systemic
1.9
13.6
206
1144
S01AD03
ATC
aciclovir; ophthalmic
3.3
13.2
65
200
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.0
13.0
173
912
D07XC01
ATC
betamethasone, combinations; topical
2.1
12.9
160
819
L03.2
ICD-10 Finland
Cellulitis of face
19.2
12.9
19
10
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
12.7
303
1948
N06AX16
ATC
venlafaxine; oral
1.8
12.6
218
1262
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
3.8
12.6
52
139
D11AH05
ATC
dupilumab; topical
+∞
12.5
12
*
R06AE09
ATC
levocetirizine; oral
1.8
12.5
242
1460
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
12.5
788
6366
R50.9
ICD-10 Finland
Fever, unspecified
1.8
12.4
221
1294
R03AC02
ATC
salbutamol; inhalant
1.5
12.4
776
6253
H60.9
ICD-10 Finland
Otitis externa, unspecified
2.3
12.3
117
532
L04AD01
ATC
ciclosporin; systemic
4.3
12.3
45
108
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.6
12.2
89
354
H04.10
ICD-10 Finland
Dry eye syndrome
2.2
11.9
124
589
501
Kela drug reimbursment
Cow's milk and / or soy protein allergy in young children
4.1
11.8
45
112
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.4
11.8
103
449
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
11.7
242
1485
L27.2
ICD-10 Finland
Dermatitis due to ingested food
3.6
11.7
51
143
C01CA24
ATC
epinephrine; parenteral
2.2
11.6
122
582
D11AX15
ATC
[U] pimecrolimus; topical
23.1
11.6
16
7
M79.6
ICD-10 Finland
Pain in limb
1.5
11.5
450
3267
SPAT1263
SPAT
Sampling
1.5
11.4
618
4807
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
5.4
11.4
33
62
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
4.1
11.3
43
107
N02AX02
ATC
tramadol; systemic, rectal
1.5
11.3
472
3476
R51.80
ICD-10 Finland
Headache
1.7
11.2
242
1503
S97
ICPC
Chronic ulcer skin
3.2
11.2
59
192
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
11.2
320
2152
Z71.8
ICD-10 Finland
Other specified counselling
1.6
11.0
358
2486
L04.0
ICD-10 Finland
Acute lymphadenitis of face, head and neck
12.0
10.8
19
16
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.3
10.8
103
472
S06.0
ICD-10 Finland
Concussion
1.9
10.8
162
893
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.7
10.8
72
273
49300
ICD-8 Finland
Asthma, bronchiale
4.3
10.8
39
93
L02.0
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of face
7.2
10.8
25
35
N05AH04
ATC
quetiapine; oral
1.7
10.7
257
1649
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.2
10.7
109
516
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
10.6
773
6339
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
10.6
135
703
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
10.5
245
1557
L04AX01
ATC
azathioprine; systemic
2.6
10.5
75
297
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
10.4
250
1599
S84
ICPC
Impetigo
5.7
10.4
29
52
N06AB04
ATC
citalopram; systemic
1.6
10.4
260
1685
L03.9
ICD-10 Finland
Cellulitis, unspecified
5.6
10.3
29
53
B00.19
ICD-10 Finland
Other vesicular dermatitis caused by the herper simplex virus
7.5
10.2
23
31
WW200
NOMESCO Finland
Immunization
3.1
10.1
53
173
S18
ICPC
Laceration/cut
1.5
10.1
481
3626
N05BA01
ATC
diazepam; systemic, rectal
1.8
10.0
161
914
J01CF05
ATC
flucloxacillin; systemic
2.9
9.9
58
204
L23.2
ICD-10 Finland
Allergic contact dermatitis due to cosmetics
5.7
9.8
27
48
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.6
9.7
278
1864
S01GX01
ATC
cromoglicic acid; ophthalmic
1.6
9.7
299
2041
P01AB01
ATC
metronidazole; oral, rectal
1.5
9.6
472
3567
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
9.6
318
2206
WZC30
NOMESCO Finland
Teaching
1.9
9.6
154
870
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
9.6
500
3829
N02AA05
ATC
oxycodone; systemic
1.9
9.4
134
728
H62.4*L01.0
ICD-10 Finland
Otitis externa in impetigo
+∞
9.4
9
*
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
5.4
9.4
27
51
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
9.3
255
1690
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.8
9.3
174
1036
134
Kela drug reimbursment
General erythroderma
13.7
9.2
15
11
SPAT1153
SPAT
Removal of sutures
1.5
9.1
346
2475
S21
ICPC
Skin texture symptom/complaint
1.8
9.1
159
925
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.7
9.1
179
1082
L04AA06
ATC
mycophenolic acid; systemic
4.1
9.1
34
85
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
9.0
213
1357
R06AX13
ATC
loratadine; oral
1.6
9.0
228
1481
127
Kela drug reimbursment
Transplant complication
4.1
8.9
33
82
ZX112
NOMESCO Finland
Subcutaneous
3.7
8.7
37
103
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
8.7
224
1460
WX002
NOMESCO Finland
Sedation and analgesia
1.6
8.7
215
1387
UJF32
NOMESCO Finland
Coloscopy
1.6
8.7
257
1735
R06AX22
ATC
ebastine; oral
1.6
8.6
228
1497
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.7
8.6
205
1307
AA1AD
NOMESCO Finland
CT of head and brain
1.6
8.6
232
1530
B00.11
ICD-10 Finland
Herpes simplex labialis
4.7
8.6
28
61
T78.4
ICD-10 Finland
Allergy, unspecified
2.2
8.6
82
376
H03.1*B00.5
ICD-10 Finland
Herpesviral dermatitis of eyelid
8.3
8.6
18
22
B00.0
ICD-10 Finland
Eczema herpeticum
9.0
8.5
17
19
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.9
8.5
125
686
D07AB01
ATC
clobetasone; topical
2.9
8.5
49
170
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
8.5
699
5778
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
3.7
8.4
35
96
H02AB09
ATC
hydrocortisone; systemic
3.0
8.4
46
156
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
5.5
8.3
23
42
R03BA05
ATC
fluticasone; inhalant
1.5
8.3
268
1846
R06.0
ICD-10 Finland
Dyspnoea
1.5
8.2
268
1847
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.0
8.2
98
495
J01MA02
ATC
ciprofloxacin; systemic
1.4
8.1
417
3167
SPAT1229
SPAT
Assessment of need for aid
2.3
8.1
71
314
L02.1
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of neck
11.8
8.1
14
12
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
4.5
8.1
27
61
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
7.9
248
1695
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
7.9
131
751
R03BA01
ATC
beclometasone; inhalant
1.7
7.8
162
994
M54.5
ICD-10 Finland
Low back pain
1.4
7.7
412
3147
SPAT1310
SPAT
Counselling related to known health issue
1.4
7.7
442
3420
L04AA01
ATC
[U] ciclosporin; systemic
4.1
7.7
28
69
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
4.1
7.7
28
69
B07.9
ICD-10 Finland
Verruca simplex
2.4
7.7
63
271
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
7.6
123
696
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
7.6
338
2491
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
7.6
406
3104
S10
ICPC
Boil/carbuncle
2.4
7.5
62
266
R03BB04
ATC
tiotropium bromide; inhalant
2.0
7.5
91
466
TKC20
NOMESCO Finland
Catheterisation of bladder
2.3
7.5
67
299
C03CA01
ATC
furosemide; systemic
1.6
7.5
204
1346
4930A
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA SINE EXACERBATIONE]
4.2
7.4
26
62
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.4
7.4
61
262
L30.8
ICD-10 Finland
Other specified dermatitis
3.2
7.3
36
114
L01CD
ICD-10 Finland
NA
+∞
7.3
7
*
N05CD07
ATC
temazepam; oral
1.9
7.3
107
586
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.7
7.3
162
1013
K02.1
ICD-10 Finland
Caries of dentine
1.3
7.3
868
7535
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.7
7.2
154
954
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
3.5
7.2
31
89
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
7.2
582
4760
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
1.8
7.1
117
667
R03AC03
ATC
terbutaline; inhalant
1.6
7.1
176
1134
B02.9
ICD-10 Finland
Zoster without complication
2.3
7.0
59
257
ZX120
NOMESCO Finland
Intravenous
1.8
7.0
111
627
N02BE01
ATC
paracetamol; systemic, rectal
1.4
7.0
1151
10459
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
7.0
185
1214
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.8
6.9
108
604
A92
ICPC
Allergy/allergic reaction NOS
2.3
6.9
59
260
N05AX12
ATC
aripiprazole; systemic
2.1
6.9
73
354
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.8
6.8
109
616
R52.2
ICD-10 Finland
Other chronic pain
2.6
6.8
46
180
L73.2
ICD-10 Finland
Hidradenitis suppurativa
5.0
6.8
20
40
48609
ICD-8 Finland
Pneumonia, unspecified
3.5
6.8
29
83
F03
ICPC
Eye discharge
1.9
6.7
95
515
J01AA02
ATC
doxycycline; systemic
1.3
6.7
956
8470
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
3.8
6.7
26
69
L70.0
ICD-10 Finland
Acne vulgaris
2.1
6.6
69
332
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.0
6.6
86
451
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
6.6
109
623
J01XC01
ATC
fusidic acid; systemic
3.9
6.6
25
65
N03AX16
ATC
pregabalin; oral
1.5
6.6
242
1714
L40.3
ICD-10 Finland
Pustulosis palmaris et plantaris
4.2
6.5
23
56
J01AA07
ATC
tetracycline; systemic
1.5
6.5
212
1463
D07AC14
ATC
methylprednisolone aceponate; topical
2.2
6.4
65
308
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.9
6.4
35
121
J20
ICD-10 Finland
Acute bronchitis
1.8
6.4
111
648
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.4
6.3
320
2409
03599
ICD-8 Finland
Erysipelas
8.2
6.3
13
16
J01FA06
ATC
roxithromycin; oral
1.3
6.3
471
3785
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
3.7
6.3
25
68
L20.8
ICD-10 Finland
Other atopic dermatitis
3.9
6.3
24
63
R95
ICPC
Chron obstructive pulmonary disease
3.9
6.3
24
63
46100
ICD-8 Finland
Acute sinusitis, Maxillaris
3.1
6.3
31
100
Q82.81
ICD-10 Finland
Keratosis follicularis [Darier-White]
+∞
6.3
6
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
6.2
108
630
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
6.2
415
3276
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.9
6.2
93
516
N05BA04
ATC
oxazepam; oral
1.4
6.2
285
2109
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
2.5
6.2
47
194
N03AX12
ATC
gabapentin; oral
1.6
6.2
162
1062
SPAT1312
SPAT
General health counselling
1.3
6.1
479
3873
K04.08
ICD-10 Finland
Other specified pulpit
1.8
6.1
105
609
S19
ICPC
Skin injury other
2.4
6.1
48
204
N05AH03
ATC
olanzapine; systemic
1.8
6.1
92
512
A07EC02
ATC
mesalazine; oral, rectal
2.0
6.1
74
380
N06AB03
ATC
fluoxetine; oral
1.6
6.1
160
1049
N91.1
ICD-10 Finland
Secondary amenorrhoea
2.7
6.1
37
137
K50.8
ICD-10 Finland
Other Crohn disease
3.3
6.1
28
86
N07BB01
ATC
disulfiram; oral
2.1
6.0
65
319
WX892
NOMESCO Finland
Monitored bed care
1.9
6.0
86
471
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1053
8102
1.73
27.18
13.0
8.9
4.1
3.9
e9/l
1.69
941
7065
709
4956
1.71
25.52
6.1
5.0
36.2
36.7
g/l
1.44
656
4641
1204
9789
1.70
23.70
9.5
6.6
81.9
79.7
u/l
0.78
1143
9239
790
5854
1.63
21.64
9.2
6.9
1.2
1.2
mmol/l
0.19
672
5009
302
1761
1.86
19.54
2.4
1.8
—
—
—
0
0
824
6316
1.57
18.63
7.7
5.8
10.8
12.4
umol/l
1.84
771
5948
61
174
3.59
18.38
1.3
1.3
—
—
—
0
0
161
769
2.20
18.16
1.8
1.6
—
—
—
0
0
713
5318
1.57
17.99
8.5
6.6
1.2
1.2
mmol/l
0.31
660
4886
940
7460
1.55
17.93
5.9
4.7
6.6
6.4
mmol/l
1.51
871
6850
713
5432
1.52
15.74
2.9
2.4
73.1
73.2
nmol/l
0.04
653
5033
211
1172
1.91
15.70
5.1
4.6
261.6
251.6
u/l
0.13
201
1115
464
3222
1.59
15.48
3.1
2.2
2.9
2.8
mg/l
0.37
410
2795
1587
14475
1.86
15.27
17.7
10.9
21.4
21.3
mg/l
0.01
1283
10957
1174
9965
1.52
15.09
5.0
3.7
11.6
9.5
mm/h
5.09
1093
9295
31
61
5.15
15.07
1.2
1.2
—
—
—
0
0
135
657
2.14
14.50
1.7
1.5
—
—
—
0
0
205
1165
1.86
14.17
1.7
1.3
1827.5
234.4
u/ml
3.96
197
1083
201
1142
1.86
13.90
3.5
2.8
10.8
10.1
g/l
1.30
190
1055
294
1869
1.69
13.79
6.3
4.7
0.8
0.8
mmol/l
4.17
280
1771
271
1691
1.71
13.61
8.9
6.9
1.1
1.1
mmol/l
0.49
255
1592
523
3831
1.52
13.42
3.4
2.4
55.5
56.4
u/l
0.17
490
3567
100
449
2.30
13.08
2.2
1.6
0.2
0.2
g/l
0.80
90
426
211
1244
1.79
12.91
6.9
5.8
1.8
1.5
mmol/l
0.48
170
978
1042
8797
1.44
12.52
5.0
3.8
668.2
1175.2
e6/l
0.23
13
106
208
1245
1.76
12.06
7.1
5.8
5.9
5.8
kpa
0.74
199
1208
99
460
2.22
11.96
2.2
1.6
1.2
1.2
g/l
0.10
92
438
519
3871
1.48
11.94
3.6
3.1
2.4
2.4
mmol/l
0.33
460
3480
203
1215
1.76
11.77
2.1
1.8
—
—
—
0
0
203
1216
1.76
11.73
4.8
3.8
1.6
1.6
%
0.58
184
1108
112
558
2.07
11.34
7.4
11.4
—
—
—
0
0
263
1705
1.64
11.31
1.8
1.7
1069.2
1168.8
nmol/l
0.95
207
1322
43
135
3.24
11.26
2.6
2.7
0.2
0.2
e9/l
0.10
38
112
1526
14018
1.61
11.14
18.2
11.7
139.4
139.6
mmol/l
1.84
1491
13630
277
1827
1.61
11.10
3.6
3.2
29.8
29.7
s
0.09
266
1780
98
468
2.16
11.07
1.7
1.7
0.5
0.2
iu/ml
0.33
12
77
202
1229
1.73
11.04
2.2
1.8
—
—
—
0
0
1530
14075
1.60
10.97
18.3
11.8
3.9
3.9
mmol/l
0.04
1489
13653
93
442
2.16
10.64
2.7
1.8
—
—
—
0
0
189
1141
1.73
10.61
3.5
2.8
0.2
0.2
g/l
0.03
174
1072
86
397
2.23
10.58
2.3
1.7
—
—
—
0
0
185
1113
1.74
10.51
18.8
17.2
1.3
1.2
inr
0.06
32
175
182
1094
1.74
10.37
7.2
5.4
4.9
4.8
kpa
0.05
171
1061
42
137
3.12
10.35
2.7
2.7
608.0
580.7
e6/l
0.10
37
111
77
343
2.30
10.31
2.6
2.3
299.5
412.9
ug/l
0.34
70
318
361
2570
1.51
10.24
3.4
2.5
6.4
6.9
e6/l
0.23
332
2257
216
1373
1.65
10.00
2.9
2.1
323.3
366.1
nmol/l
2.48
206
1278
175
1058
1.72
9.77
6.7
6.1
5.1
5.1
kpa
0.19
161
1002
184
1128
1.70
9.76
6.8
8.5
1.3
0.9
mmol/l
0.66
151
878
26
64
4.11
9.71
1.5
1.3
25.7
15.7
u/ml
—
7
12
405
2989
1.46
9.52
3.3
2.6
335.9
4448.8
umol/l
7.34
349
2676
28
74
3.83
9.51
5.4
4.5
8.2
8.8
mg/l
0.18
21
67
1238
11024
1.40
9.48
4.2
3.8
14.4
14.5
pmol/l
0.82
1146
10178
170
1029
1.72
9.45
6.6
6.2
1.4
1.3
mmol/l
0.10
123
745
439
3294
1.44
9.44
2.5
2.1
165.0
246.7
u/l
1.36
417
3136
558
4376
1.40
9.34
2.0
1.8
92.2
96.4
pmol/l
1.63
324
2416
274
1882
1.54
9.12
3.0
2.4
13.3
14.3
umol/l
1.09
260
1759
1610
15136
1.64
8.93
12.8
8.6
27.4
27.2
u/l
0.16
1575
14677
40
139
2.92
8.88
2.5
2.6
11.7
10.5
%
0.29
30
93
175
1086
1.68
8.87
12.3
9.1
7.7
7.5
mmol/l
0.21
170
1048
233
1556
1.57
8.77
3.1
2.5
21.9
24.0
%
1.07
196
1362
23
56
4.15
8.72
1.3
1.4
—
71.3
—
0
8
68
310
2.24
8.67
7.2
7.1
206.9
303.8
iu/ml
—
8
47
316
2264
1.48
8.56
1.7
1.6
33712576.4
30785442.4
pmol/l
0.03
264
1949
1601
15061
1.60
8.48
18.3
11.8
72.4
72.0
umol/l
0.18
1601
15056
750
6242
1.35
8.44
4.7
3.9
—
—
—
0
0
164
1014
1.68
8.43
8.3
8.3
1.4
1.3
mmol/l
0.31
157
962
12
16
7.54
8.41
1.3
1.7
—
—
—
0
0
452
3473
1.40
8.37
4.0
3.0
0.2
0.4
e6/l
3.05
354
2564
221
1477
1.57
8.28
3.9
3.2
6.9
7.2
umol/l
0.07
185
1262
16
30
5.37
8.21
1.1
1.2
—
—
—
0
0
510
4011
1.38
8.19
3.5
3.0
37.4
52.7
ng/l
0.36
314
2250
23
59
3.94
8.16
1.3
1.5
—
322.0
—
0
5
95
504
1.93
8.13
4.7
4.5
3.5
3.3
g/l
0.44
86
480
170
1075
1.64
8.01
2.9
2.4
9365.7
4600.3
u/l
0.77
58
415
328
2396
1.45
8.01
1.6
1.4
20.1
20.1
nmol/l
0.01
286
2094
79
395
2.05
7.99
2.3
2.1
1.3
1.4
g/l
0.79
69
347
37
131
2.86
7.98
2.5
2.6
—
—
—
0
0
177
1134
1.62
7.92
7.0
8.4
5.1
5.1
kpa
0.05
168
1081
177
1134
1.62
7.92
6.9
8.4
12.1
12.9
kpa
1.49
167
1085
296
2125
1.47
7.90
3.7
2.6
142.8
102.9
ug/g
1.00
240
1700
570
4587
1.36
7.86
4.5
3.3
31.0
31.0
u/l
0.00
542
4363
1373
12583
1.39
7.85
14.4
9.5
92.1
90.9
ml/min/173m2
1.09
1106
10094
389
2952
1.41
7.67
2.7
2.1
0.9
1.1
mg/l
1.31
296
2143
126
744
1.75
7.66
3.1
2.5
67.6
67.3
g/l
0.23
117
691
198
1317
1.57
7.57
8.2
7.5
104.5
104.6
mmol/l
0.13
192
1288
98
540
1.86
7.49
1.3
1.2
0.2
1.5
u/ml
1.26
11
41
69
337
2.09
7.45
2.1
1.7
—
—
—
0
0
244
1706
1.50
7.41
3.0
2.4
2.4
2.4
g/l
0.79
232
1588
109
626
1.79
7.30
7.1
7.4
9.5
9.4
kpa
0.20
102
593
139
860
1.67
7.14
7.4
6.4
24.1
23.8
mmol/l
0.63
130
799
456
3589
1.36
7.14
4.2
3.4
0.0
0.0
estimate
1.08
176
1301
56
258
2.21
7.02
1.3
1.3
—
—
—
0
0
56
258
2.21
7.02
1.3
1.3
—
—
—
0
0
456
3604
1.36
6.92
4.4
3.3
7.9
8.4
mmol/l
1.27
408
3109
59
280
2.14
6.88
4.0
3.4
4.9
3.9
e9/l
2.08
59
280
255
1834
1.46
6.70
3.0
2.7
2.4
2.4
mmol/l
0.89
213
1614
491
3942
1.34
6.68
1.5
1.4
1.4
1.8
u/ml
0.48
123
999
60
290
2.11
6.68
4.5
3.7
60.1
55.4
%
1.87
60
290
327
2465
1.40
6.62
3.7
3.2
1455.9
1020.7
ng/l
0.74
278
2050
12
21
5.75
6.59
2.0
2.0
1.6
1.8
mg/l
—
7
16
792
6813
1.29
6.47
3.4
2.8
95.3
93.4
ug/l
0.11
736
6390
170
1137
1.55
6.35
4.0
2.7
—
—
—
0
0
1396
12980
1.34
6.14
5.1
4.3
2.0
1.9
mu/l
0.06
1309
12168
127
807
1.62
5.91
6.8
6.5
24.5
24.5
mmol/l
0.04
122
783
34
136
2.53
5.88
2.6
2.3
882.6
773.5
e6/l
0.31
12
40
21
64
3.31
5.86
1.5
1.5
—
965700.0
iu/ml
—
0
5
391
3089
1.34
5.84
2.9
2.2
—
—
—
0
0
116
727
1.64
5.71
3.3
3.3
102.6
159.2
ng/l
2.10
105
650
49
234
2.12
5.68
2.3
1.8
—
—
—
0
0
19
56
3.42
5.59
1.4
1.2
0.3
0.3
g/l
0.31
13
48
172
1186
1.50
5.58
2.9
2.2
29.2
74.4
u/l
0.58
146
1009
96
583
1.68
5.35
1.9
1.6
—
—
—
0
0
784
6846
1.26
5.32
3.9
3.2
0.0
0.0
estimate
0.80
173
1290
90
538
1.71
5.32
8.7
10.7
24.7
24.3
mmol/l
0.67
84
512
22
74
3.00
5.26
2.2
2.7
1215.3
930.1
u/ml
0.29
22
74
27
102
2.67
5.25
1.9
1.5
—
—
—
0
0
27
102
2.67
5.25
1.9
1.5
—
—
—
0
0
27
102
2.67
5.25
1.9
1.5
—
—
—
0
0
57
298
1.94
5.20
7.0
4.9
24.0
24.4
mmol/l
0.25
51
268
371
2955
1.32
5.18
4.1
3.3
1.0
1.0
kg/l
0.32
58
421
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
57
299
1.94
5.15
3.1
8.1
0.3
0.4
u/ml
0.41
35
163
57
300
1.93
5.10
2.6
2.0
10.5
10.6
g/l
0.04
47
263
57
302
1.92
5.01
2.7
3.0
32.6
34.2
umol/l
0.27
50
272
269
2057
1.36
4.93
3.3
2.7
1.0
1.0
e6/l
0.03
162
1137
25
94
2.68
4.92
1.5
1.7
16.6
24.9
umol/l
1.01
25
88
62
340
1.85
4.91
2.2
1.7
—
—
—
0
0
1090
9938
1.25
4.86
3.9
3.0
46.7
41.2
u/l
1.13
1030
9487
772
6782
1.24
4.81
3.9
3.2
0.0
0.0
estimate
0.00
179
1288
48
244
1.99
4.76
1.7
1.8
—
—
—
0
0
54
288
1.90
4.67
1.3
1.3
—
—
—
0
0
772
6797
1.24
4.67
5.2
4.4
0.0
0.0
estimate
0.50
176
1337
298
2335
1.33
4.64
1.3
1.2
19.3
26.0
iu/ml
1.20
81
702
1706
16581
1.64
4.55
25.5
16.0
4.5
4.6
e12/l
6.38
1665
16131
373
3027
1.29
4.49
2.4
2.2
—
—
—
0
0
270
2095
1.34
4.49
4.4
3.3
201.1
642.7
ng/l
3.22
170
1382
45
229
1.99
4.47
2.3
2.3
16.7
17.1
%
0.29
28
114
46
236
1.97
4.47
3.9
3.5
78.6
75.1
mg/l
0.03
39
185
46
236
1.97
4.47
3.9
3.5
28.5
30.6
mg/l
0.18
38
186
283
2213
1.33
4.46
1.9
1.7
1.5
1.4
%
1.56
244
1987
29
124
2.36
4.42
2.8
1.4
1.8
1.2
promille
0.95
23
100
281
2200
1.33
4.39
1.3
1.2
5.5
10.2
u/ml
1.10
103
914
611
5274
1.24
4.36
4.0
3.2
—
—
—
0
0
57
318
1.82
4.32
2.1
1.6
—
—
—
0
0
1705
16586
1.61
4.31
25.6
16.0
7.0
6.7
e9/l
3.17
1665
16123
1705
16592
1.60
4.23
25.7
16.1
135.1
136.9
g/l
6.06
1692
16393
1253
11680
1.24
4.22
5.0
4.5
39.0
38.2
mmol/mol
1.71
1169
11020
1702
16560
1.58
4.17
25.6
16.0
262.8
257.4
e9/l
2.56
1672
16128
23
91
2.55
4.13
1.5
1.6
—
—
—
0
0
22
86
2.58
4.05
7.0
3.7
—
—
—
0
0
57
325
1.78
4.04
2.6
2.0
7.1
7.3
g/l
0.34
42
258
57
325
1.78
4.04
2.6
2.0
4.6
3.8
g/l
0.84
42
245
57
325
1.78
4.04
2.6
2.0
—
—
—
0
0
61
355
1.74
4.03
1.5
1.4
283.4
315.0
ug/g
0.49
31
194
124
858
1.48
4.01
4.4
3.2
1.2
1.2
mmol/l
0.03
112
741
80
502
1.62
4.00
1.2
1.1
2.2
2.6
u/ml
0.22
35
148
29
131
2.23
3.93
2.1
1.9
—
—
—
0
0
10
24
4.18
3.89
3.1
3.0
—
—
—
0
0
10
24
4.18
3.89
1.1
1.0
0.0
0.0
u/ml
—
5
15
482
4102
1.24
3.84
1.9
1.7
—
—
—
0
0
31
147
2.13
3.75
1.4
1.3
—
—
—
0
0
86
560
1.56
3.71
1.2
1.2
4.3
2.7
u/ml
0.33
60
288
31
149
2.10
3.64
1.4
1.3
—
—
—
0
0
48
269
1.81
3.63
1.2
1.3
0.9
4.9
u/ml
—
5
23
31
150
2.09
3.58
1.4
1.3
—
—
—
0
0
119
837
1.45
3.57
5.7
5.0
72.4
73.7
ng/l
0.07
104
766
7
9
7.80
3.56
6.1
9.8
—
—
—
0
0
30
144
2.10
3.54
1.4
1.5
276.8
354.7
pmol/l
0.98
22
117
48
272
1.79
3.51
1.4
1.3
—
—
—
0
0
249
1978
1.30
3.50
3.6
2.9
2.5
2.6
e6/l
0.13
137
1062
38
200
1.92
3.49
2.1
1.7
—
—
—
0
0
27
125
2.18
3.48
1.6
2.1
—
—
—
0
0
52
303
1.74
3.47
1.3
1.1
—
—
—
0
0
33
166
2.01
3.45
2.3
1.8
—
—
—
0
0
88
587
1.52
3.43
1.8
1.8
—
—
—
0
0
94
637
1.50
3.41
8.7
10.2
93.3
94.0
%
0.30
94
632
60
366
1.66
3.40
1.9
2.0
3.2
1.9
ug/l
0.27
46
327
12
37
3.26
3.34
1.0
1.1
1.2
3.6
u/ml
—
7
26
18
71
2.55
3.29
2.0
2.1
329.1
170.0
umol/l
—
10
37
22
96
2.31
3.27
2.5
2.1
—
—
—
0
0
52
309
1.70
3.25
2.8
2.0
2.9
3.1
g/l
0.71
42
249
15
54
2.79
3.25
2.5
1.6
—
—
—
0
0
15
54
2.79
3.25
2.5
1.6
—
—
—
0
0
15
54
2.79
3.25
2.5
1.6
—
—
—
0
0
15
54
2.79
3.25
2.5
1.6
—
—
—
0
0
353
2970
1.23
3.07
4.4
4.0
58.0
9.4
mg/mmol
0.54
243
1969
17
68
2.51
3.04
1.4
1.1
—
—
—
0
0
29
147
1.99
3.00
1.4
1.3
—
—
—
0
0
29
147
1.99
3.00
1.4
1.3
—
—
—
0
0
29
148
1.98
2.95
1.4
1.3
—
—
—
0
0
1344
12787
1.21
2.93
4.0
3.6
5.8
5.7
mmol/l
1.36
1233
11892
203
1609
1.30
2.92
2.2
2.0
—
—
—
0
0
33
177
1.88
2.92
1.7
1.5
—
—
—
0
0
125
924
1.38
2.89
3.0
2.3
69.1
75.3
ml/min/173m2
0.89
48
340
54
336
1.63
2.88
2.9
1.9
133.1
1692.6
e6/l
1.05
47
269
54
336
1.63
2.88
2.9
1.9
7.3
10.8
e6/l
0.30
44
259
22
102
2.17
2.87
1.1
1.0
—
—
—
0
0
379
3237
1.22
2.84
1.8
1.6
1.4
1.4
mmol/l
0.47
335
2821
16
65
2.47
2.79
1.6
2.6
—
—
—
0
0
16
65
2.47
2.79
1.6
2.6
—
—
—
0
0
9
23
3.93
2.77
1.0
1.2
—
—
—
0
0
31
166
1.88
2.77
2.1
1.5
—
—
—
0
0
106
768
1.40
2.76
2.7
2.2
6.6
8.1
ug/l
0.22
90
684
67
444
1.53
2.75
2.0
1.5
229.5
242.3
u/ml
0.10
35
261
12
42
2.87
2.75
3.2
2.5
—
—
—
0
0
130
1708
0.74
2.74
1.5
1.6
—
—
—
0
0
69
461
1.52
2.73
1.9
1.4
—
—
—
0
0
30
160
1.89
2.71
1.3
1.2
—
—
—
0
0
28
146
1.93
2.70
1.8
1.5
—
—
—
0
0
15
60
2.51
2.70
1.0
1.4
73.8
92.8
%
—
6
33
60
390
1.56
2.69
1.8
1.7
—
11.2
—
0
5
164
1278
1.31
2.69
6.6
5.4
—
—
—
0
0
42
250
1.70
2.66
1.4
1.2
1.8
5.4
u/ml
1.97
20
106
15
61
2.47
2.62
1.0
1.1
81.2
94.1
%
—
6
34
12
44
2.74
2.54
1.3
1.2
8.0
8.7
ug/l
0.28
12
44
63
421
1.51
2.51
1.2
1.1
—
—
—
0
0
11
39
2.83
2.47
6.4
10.0
—
—
—
0
0
33
188
1.77
2.46
1.6
1.2
—
—
—
0
0
34
196
1.75
2.43
2.4
1.6
—
—
—
0
0
47
297
1.60
2.40
3.0
2.9
—
—
—
0
0
9
27
3.34
2.39
4.2
5.4
—
—
—
0
0
62
418
1.50
2.39
1.2
1.1
—
—
—
0
0
382
3318
1.19
2.38
2.5
2.3
—
—
—
0
0
41
251
1.65
2.38
1.4
1.2
1.5
2.9
u/ml
0.82
11
85
64
435
1.49
2.37
1.9
2.0
—
—
—
0
0
18
84
2.15
2.35
2.9
1.6
—
—
—
0
0
52
342
1.54
2.26
1.3
1.3
1.5
2.6
u/ml
—
8
38
30
171
1.77
2.25
4.4
3.5
1.2
1.2
%
0.03
20
144
9
29
3.11
2.22
1.0
1.2
—
—
—
0
0
21
107
1.97
2.20
1.1
1.1
—
—
—
0
0
21
108
1.96
2.15
1.1
1.1
—
—
—
0
0
30
174
1.74
2.14
1.1
1.1
—
—
—
0
0
40
251
1.61
2.13
1.9
2.3
129.7
134.4
g/l
0.57
34
192
18
88
2.06
2.11
1.2
1.2
—
—
—
0
0
1329
12752
1.16
2.11
21.4
13.5
13.6
13.4
%
2.45
1320
12487
52
348
1.51
2.11
1.3
1.3
2.6
12.1
u/ml
1.49
11
59
236
1984
1.22
2.08
2.4
2.1
—
—
—
0
0
17
82
2.08
2.07
1.1
1.1
1743.5
1637.5
miu/ml
0.12
17
82
17
82
2.08
2.07
1.8
1.3
—
—
—
0
0
21
110
1.92
2.06
1.4
1.1
105.2
92.2
u/l
0.11
16
74
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
19
97
1.97
2.00
1.3
1.2
—
—
—
0
0
35
217
1.63
1.98
1.2
1.3
—
32.0
—
0
5
5
11
4.55
1.94
1.0
1.2
—
—
—
0
0
37
235
1.59
1.91
1.5
1.7
9591.0
10608.7
e6/l
0.06
29
175
54
373
1.46
1.90
1.9
1.7
113.1
99.2
u/ml
—
9
59
27
158
1.72
1.89
2.5
1.7
—
—
—
0
0
25
143
1.76
1.89
2.4
1.6
—
—
—
0
0
22
121
1.83
1.88
1.0
1.1
—
—
—
0
0
14
65
2.16
1.88
1.0
1.0
167.9
251.2
iu/ml
0.61
14
65
49
333
1.48
1.88
2.4
1.7
3.5
3.7
mmol/l
1.34
44
315
9
34
2.66
1.86
1.9
1.5
—
—
—
0
0
20
107
1.88
1.86
1.2
1.1
—
—
—
0
0
20
107
1.88
1.86
1.2
1.1
—
—
—
0
0
20
107
1.88
1.86
1.2
1.1
—
—
—
0
0
75
554
1.37
1.83
1.5
2.0
39.0
39.2
u/l
0.03
67
515
10
40
2.51
1.83
1.0
1.1
—
—
—
0
0
36
230
1.58
1.82
2.3
1.6
—
—
—
0
0
127
1013
1.27
1.82
1.7
1.5
20.1
23.1
iu/l
0.51
101
824
89
677
1.33
1.81
2.0
1.5
9.6
8.3
u/l
0.36
67
522
8
29
2.77
1.79
1.0
1.1
—
—
—
0
0
30
184
1.64
1.79
1.1
1.1
—
—
—
0
0
10
41
2.45
1.75
1.0
1.0
1.0
0.2
u/ml
—
5
24
6
18
3.34
1.74
1.8
1.3
—
—
—
0
0
6
18
3.34
1.74
1.2
1.1
—
—
—
0
0
76
568
1.35
1.74
1.4
1.4
—
—
—
0
0
8
30
2.67
1.72
1.4
1.5
—
—
—
0
0
31
194
1.61
1.72
2.3
1.5
—
—
—
0
0
5
13
3.85
1.71
4.6
2.4
—
—
—
0
0
15
75
2.01
1.69
3.1
1.9
—
—
—
0
0
145
1187
1.24
1.68
2.1
2.1
11.5
12.7
nmol/l
1.03
129
1063
8
31
2.59
1.66
1.8
2.8
—
—
—
0
0
8
31
2.59
1.66
1.8
2.8
—
—
—
0
0
11
49
2.25
1.63
1.4
1.2
—
—
—
0
0
5
14
3.58
1.61
1.6
1.6
—
—
—
0
0
5
14
3.58
1.61
1.8
1.4
—
—
—
0
0
24
143
1.69
1.61
1.7
1.5
—
—
—
0
0
12
57
2.11
1.55
1.6
1.1
42.9
13.6
u/l
0.91
12
48
14
71
1.98
1.54
1.0
1.1
91.9
91.7
%
—
8
59
8
33
2.43
1.53
1.0
1.3
—
—
—
0
0
22
130
1.70
1.53
1.2
1.3
3.3
5.2
umol/l
2.30
22
120
5
15
3.34
1.52
1.6
3.0
—
—
—
0
0
5
15
3.34
1.52
1.0
1.3
—
—
—
0
0
35
234
1.51
1.50
1.1
1.2
106.3
111.9
%
0.46
29
217
12
58
2.08
1.49
1.3
1.2
—
—
—
0
0
17
94
1.82
1.47
1.3
1.2
—
40.7
—
0
6
22
132
1.67
1.46
1.1
1.3
0.9
0.4
u/ml
—
10
44
5
16
3.13
1.44
2.6
3.5
21.2
1588.6
u/l
—
5
16
12
59
2.04
1.43
1.6
1.1
112.3
88.9
u/l
0.28
12
51
1375
13343
1.13
1.43
4.0
3.7
4.6
4.7
mmol/l
1.63
1298
12634
9
39
2.31
1.43
2.4
2.2
—
—
—
0
0
9
40
2.26
1.40
1.3
1.9
—
—
—
0
0
49
356
1.39
1.38
1.2
1.1
11.1
4.9
u/ml
1.43
37
171
23
142
1.63
1.38
1.1
1.1
—
—
—
0
0
12
60
2.01
1.38
1.2
3.0
1.8
2.3
mmol/l
—
7
46
1467
14306
1.14
1.37
18.3
11.8
40.1
40.4
%
1.00
1145
11649
48
351
1.38
1.32
2.9
2.7
8.1
6.2
umol/l
0.25
36
270
25
160
1.57
1.31
1.1
1.0
—
—
—
0
0
119
985
1.22
1.29
2.3
2.3
52.2
22.8
au/ml
—
6
73
110
904
1.23
1.28
1.3
1.2
23.5
37.8
au/ml
—
5
41
5
18
2.78
1.28
2.2
4.7
38.0
45.7
umol/l
—
5
12
19
114
1.67
1.28
1.5
1.2
—
—
—
0
0
6
135
0.44
1.27
1.2
1.4
30.4
31.7
nmol/l
—
6
115
19
115
1.66
1.25
1.5
1.2
—
—
—
0
0
1314
12753
1.11
1.24
3.6
3.3
1.3
1.3
mmol/l
1.94
1236
12011
12
63
1.91
1.22
1.3
1.2
—
—
—
0
0
18
108
1.67
1.22
2.3
2.5
30.2
32.8
pg
1.11
18
108
10
49
2.05
1.22
1.0
1.1
—
—
—
0
0
10
49
2.05
1.22
1.0
1.1
—
—
—
0
0
23
148
1.56
1.20
1.0
1.1
14.6
6.1
iu/ml
—
5
32
6
26
2.31
1.18
5.3
6.8
—
—
—
0
0
6
26
2.31
1.18
5.5
6.9
—
—
—
0
0
0
33
0.00
1.16
0.0
2.3
—
—
—
0
0
105
875
1.21
1.10
1.8
1.6
376.2
306.8
mu/l
1.13
93
785
51
390
1.32
1.09
1.2
1.1
5.8
5.1
u/ml
0.11
37
171
103
860
1.21
1.07
3.7
4.3
24.7
25.6
ug/l
0.02
82
673
24
161
1.50
1.07
2.4
4.2
38.1
124.6
u/ml
—
7
45
7
33
2.13
1.05
3.9
6.4
—
—
—
0
0
1379
13460
1.11
1.05
4.2
3.9
2.8
2.8
mmol/l
1.04
1292
12655
5
22
2.28
1.03
8.2
8.1
—
—
—
0
0
35
255
1.38
1.03
1.1
1.1
—
—
—
0
0
18
114
1.58
1.02
1.0
1.1
—
—
—
0
0
7
35
2.00
1.00
2.9
2.1
—
—
—
0
0
9
49
1.84
0.98
1.0
1.1
—
—
—
0
0
9
49
1.84
0.98
1.0
1.1
—
—
—
0
0
5
23
2.18
0.98
1.2
1.0
—
—
—
0
0
20
132
1.52
0.97
1.1
1.0
—
—
—
0
0
10
54
1.86
0.96
4.1
1.6
—
—
—
0
0
10
54
1.86
0.96
4.1
1.6
—
—
—
0
0
28
199
1.41
0.95
1.4
1.2
—
—
—
0
0
9
51
1.77
0.94
1.1
1.1
—
—
—
0
0
9
51
1.77
0.94
1.1
1.1
—
—
—
0
0
9
52
1.73
0.92
1.1
1.2
—
—
—
0
0
34
252
1.36
0.92
1.5
1.4
—
—
—
0
0
24
167
1.44
0.92
1.3
1.3
0.6
0.6
nmol/l
0.16
24
159
122
1052
1.17
0.91
1.1
1.1
—
—
—
0
0
6
29
2.07
0.89
1.2
1.1
—
—
—
0
0
22
152
1.45
0.88
1.2
1.1
27.9
37.1
mg/l
1.10
17
117
39
298
1.32
0.88
1.2
1.2
21.3
37.3
u/ml
—
7
26
6
30
2.00
0.87
1.0
1.0
—
—
—
0
0
11
64
1.72
0.86
3.8
1.5
—
—
—
0
0
8
44
1.82
0.86
1.1
1.1
—
—
—
0
0
64
524
1.23
0.84
1.4
1.3
—
—
—
0
0
8
45
1.78
0.84
1.1
1.2
—
—
—
0
0
8
45
1.78
0.84
3.8
1.6
—
—
—
0
0
8
45
1.78
0.84
1.1
1.2
—
—
—
0
0
8
45
1.78
0.84
3.8
1.6
—
—
—
0
0
62
507
1.23
0.83
1.1
1.1
10.5
5.1
u/ml
—
7
81
6
115
0.52
0.82
1.0
1.5
0.9
1.0
g/l
—
6
115
8
46
1.74
0.82
3.8
1.6
—
—
—
0
0
1355
13266
1.09
0.82
3.9
3.6
1.4
1.4
mmol/l
2.44
1268
12504
43
337
1.28
0.82
4.3
3.5
123.3
1230.4
u/ml
1.24
38
288
43
337
1.28
0.82
1.1
1.1
1.0
0.5
u/ml
0.44
25
108
8
48
1.67
0.78
4.0
1.7
—
—
—
0
0
23
165
1.40
0.77
2.7
1.5
—
—
—
0
0
168
1871
0.89
0.77
2.8
2.7
0.6
0.7
ug/l
0.75
96
1082
0
28
0.00
0.76
0.0
1.1
—
—
—
0
0
9
54
1.67
0.74
1.1
1.3
—
—
—
0
0
9
54
1.67
0.74
1.1
1.3
—
—
—
0
0
138
1224
1.14
0.74
1.3
1.2
152.7
142.2
iu/ml
0.10
50
476
24
176
1.37
0.72
1.1
1.1
90.3
92.5
%
0.13
24
167
22
159
1.39
0.72
1.3
1.5
11.7
11.8
mmol/l
—
6
30
87
750
1.17
0.70
1.3
1.3
172.8
233.7
miu/ml
1.36
47
380
9
59
1.53
0.68
3.2
4.2
—
—
—
0
0
57
681
0.83
0.68
1.4
1.7
6.3
3.6
mg/l
1.05
42
452
149
1338
1.12
0.67
3.0
3.7
30.2
31.5
%
0.64
92
963
103
903
1.15
0.67
4.5
3.4
4.6
4.7
pmol/l
0.53
96
811
31
241
1.29
0.66
2.7
2.4
226.2
97.5
ug/min
0.29
20
152
11
70
1.57
0.65
1.5
1.6
13.7
4.6
nmol/l
0.30
11
57
11
70
1.57
0.65
1.0
1.0
—
—
—
0
0
65
762
0.85
0.64
1.5
1.5
—
—
—
0
0
8
52
1.54
0.59
1.1
1.1
—
—
—
0
0
44
363
1.22
0.59
1.6
1.9
—
—
—
0
0
86
753
1.15
0.59
2.4
1.8
—
—
—
0
0
18
131
1.38
0.59
16.1
14.2
920.6
772.8
nmol/l
0.56
18
125
47
391
1.21
0.58
1.4
1.4
—
—
—
0
0
15
106
1.42
0.57
1.5
1.5
1.6
1.8
mmol/l
1.59
15
101
34
274
1.25
0.57
1.3
1.2
—
—
—
0
0
10
65
1.54
0.55
4.5
2.4
8.3
10.3
mg/l
—
10
53
1219
11966
1.06
0.53
3.9
3.6
—
—
—
0
0
14
100
1.40
0.51
1.6
1.5
—
—
—
0
0
17
126
1.35
0.51
1.4
1.5
12.0
11.3
umol/l
0.16
17
117
7
45
1.56
0.49
3.7
2.8
156.6
105.2
ug/l
—
7
45
39
327
1.20
0.47
1.5
1.5
0.4
0.3
nmol/l
0.13
34
263
14
102
1.38
0.47
1.1
1.2
—
—
u/ml
—
0
0
33
273
1.21
0.46
1.5
1.1
315591.1
1784.9
iu/ml
—
7
74
7
50
1.40
0.45
2.4
2.3
15.5
19.7
umol/l
—
7
50
40
339
1.18
0.44
4.1
4.0
1.5
1.4
mmol/l
0.11
40
331
5
31
1.61
0.43
1.0
1.1
—
—
—
0
0
5
31
1.61
0.43
1.0
1.0
—
—
—
0
0
34
285
1.20
0.42
1.5
1.4
16.4
20.1
u/l
0.38
28
236
5
32
1.56
0.42
1.0
1.1
—
—
—
0
0
62
699
0.88
0.41
1.5
1.4
—
—
—
0
0
62
698
0.88
0.40
1.5
1.4
—
—
—
0
0
62
698
0.88
0.40
1.5
1.4
—
—
—
0
0
8
61
1.31
0.39
1.1
1.2
163.9
433.1
u/l
—
8
56
62
696
0.89
0.39
1.5
1.4
—
—
—
0
0
72
647
1.12
0.38
1.7
1.7
—
—
—
0
0
12
158
0.76
0.37
1.1
1.1
—
—
—
0
0
9
71
1.27
0.36
1.3
1.6
1.0
4.2
u/field
—
9
58
20
162
1.24
0.35
4.1
1.6
—
—
—
0
0
47
532
0.88
0.35
1.7
1.5
—
—
—
0
0
20
163
1.23
0.34
3.9
3.4
45.2
24.4
u/ml
0.75
20
158
23
275
0.83
0.33
3.3
3.3
18.8
23.6
mg/l
0.50
13
169
14
111
1.26
0.30
1.1
1.0
1.1
1.0
u/l
—
7
53
13
102
1.28
0.30
1.2
1.4
1.0
1.5
nmol/l
1.73
13
93
26
303
0.86
0.29
1.0
1.1
3.8
2.1
u/ml
—
10
146
58
525
1.11
0.29
1.1
1.1
—
—
—
0
0
106
990
1.08
0.28
1.3
1.4
—
—
—
0
0
96
901
1.07
0.23
1.6
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
43.9
—
0
5
135
1412
0.95
0.20
1.5
1.5
—
—
—
0
0
6
51
1.18
0.19
1.0
1.1
16.1
41.4
u/ml
—
6
51
6
51
1.18
0.19
1.0
1.0
—
—
—
0
0
81
764
1.06
0.19
1.7
1.9
—
—
—
0
0
24
213
1.13
0.18
1.2
1.1
—
—
—
0
0
323
3151
1.03
0.18
3.7
4.0
2.2
2.1
ug/l
0.12
290
2873
66
702
0.94
0.17
1.5
1.6
—
—
—
0
0
37
339
1.09
0.17
1.2
1.2
—
—
—
0
0
43
397
1.09
0.17
2.3
1.9
2.8
5.2
iu/l
3.00
18
149
11
92
1.20
0.16
2.2
1.8
—
—
—
0
0
15
172
0.87
0.15
1.3
1.5
—
—
—
0
0
12
107
1.12
0.08
2.0
1.3
—
—
—
0
0
6
58
1.03
0.08
1.2
1.0
—
—
—
0
0
30
318
0.94
0.08
2.9
2.0
0.6
0.8
nmol/l
0.88
24
276
11
98
1.12
0.07
1.3
1.1
—
—
—
0
0
57
591
0.96
0.07
1.5
1.5
—
—
—
0
0
23
217
1.06
0.06
1.3
1.4
6.4
6.8
mmol/l
0.31
17
151
33
344
0.96
0.05
1.3
1.5
—
—
—
0
0
250
2516
0.99
0.02
3.5
3.5
21.2
20.9
%
0.09
86
1012
266
2675
0.99
0.02
1.5
1.5
—
—
—
0
0
60
607
0.99
0.01
1.5
1.4
—
—
—
0
0
10
96
1.04
0.00
4.1
4.6
1.2
1.6
ug/l
—
10
91
18
176
1.02
0.00
1.1
1.1
—
—
—
0
0
30
295
1.02
0.00
1.1
1.1
—
—
—
0
0
13
130
1.00
0.00
1.2
1.9
—
—
—
0
0
14
139
1.01
0.00
1.2
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
6.7
—
—
—
0
0
7
70
1.00
0.00
1.1
1.3
—
—
—
0
0
7
72
0.97
0.00
1.0
1.1
—
—
—
0
0
7
73
0.96
0.00
3.3
2.2
44.1
48.4
umol/l
—
7
61
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
6
59
1.02
0.00
1.7
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
8.7
—
0
5
0
6
0.00
0.00
0.0
5.5
—
424.0
—
0
6
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
8
87
0.92
0.00
2.3
1.5
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_IMPETIGO and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_IMPETIGO | 2.412 [1.88, 3.09] | < 0.001 |
| Birth year | 0.995 [0.98, 1.0] | 0.296 |
During the follow-up period (1.1.1998 — 31.12.2019), 434 out of 8762 females with L12_IMPETIGO died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_IMPETIGO | 2.621 [2.05, 3.35] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.068 |
During the follow-up period (1.1.1998 — 31.12.2019), 538 out of 9066 males with L12_IMPETIGO died.
Mortality risk
Mortality risk for people of age
years, who have L12_IMPETIGO.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.191% | 0.601% |
| 5 | 1.282% | 3.415% |
| 10 | 3.315% | 8.425% |
| 15 | 6.262% | 15.572% |
| 20 | 11.018% | 26.219% |
Relationships between endpoints
↥Index endpoint: L12_IMPETIGO – Impetigo
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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