Nontoxic multinodular goitre

E4_GOITREMULTINOD

nodular goiter: Goiter characterized by discrete tissue mass(es) that may or may not produce thyroid hormones.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E04.2
  • Hospital discharge: ICD-9 2411
  • Hospital discharge: ICD-8 241
  • Cause of death: ICD-10 E04.2
  • Cause of death: ICD-9 2411
  • Cause of death: ICD-8 241

2 out of 7 registries used, show all original rules.

8855

4. Check minimum number of events

None

8855

5. Include endpoints

None

8855

6. Filter based on genotype QC (FinnGen only)

8586

Control definitions (FinnGen only)

Control exclude
E4_THYROID

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E04
Name in latin
Struma atoxica multinodularis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 61722 52630 8754
Only index persons 53558 46255 7303
Unadjusted period prevalence (%)
Whole population 1.32 1.51 0.24
Only index persons 1.51 1.70 0.28
Median age at first event (years)
Whole population 53.21 52.57 57.09
Only index persons 52.22 51.51 56.67

-FinnGen-

Key figures

All Female Male
Number of individuals 8586 7233 1353
Unadjusted period prevalence (%) 2.26 2.57 0.62
Median age at first event (years) 52.93 51.52 60.42

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
8855
Matched controls
88549
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
192.5
307.7
2091
142
E05.80
ICD-10 Finland
Subacute thyrotoxicosis
59.9
307.7
205
35
2504
FHL
Unilateral resection or enucleation
69.2
307.7
378
57
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
86.1
307.7
1486
207
E04.8
ICD-10 Finland
Other specified nontoxic goitre
86.5
307.7
203
24
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
96.0
307.7
270
29
EP1AE
NOMESCO Finland
Neck ultrasound examination
7.4
307.7
1337
2072
BAA60
NOMESCO Finland
Total thyroidectomy
2422.9
307.7
1669
9
H03AA01
ATC
levothyroxine sodium; systemic
95.9
307.7
4767
1064
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
216.2
307.7
333
16
BAA20
NOMESCO Finland
Unilateral partial excision of thyroid gland
179.2
307.7
210
12
E03.89
ICD-10 Finland
Other specified hypothyroidism
169.7
307.7
732
47
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
34.7
307.7
768
242
104
Kela drug reimbursment
Thyroid insufficiency
911.6
307.7
2246
33
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
33.2
307.7
829
275
E03
ICD-10 Finland
Other hypothyroidism
117.9
307.7
853
80
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
170.6
307.7
407
25
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
111.7
307.7
766
75
H03BB01
ATC
carbimazole; oral
64.5
307.7
517
85
2505
FHL
Bilateral resection (also used if total removal has been performed on the other side)
135.7
307.7
377
29
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
150.6
307.7
1888
159
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
137.3
307.7
175
13
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
3908.4
307.7
1069
*
T86
ICPC
Hypothyroidism/myxoedema
60.9
307.7
645
114
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
2031.3
307.7
6971
161
2411A
ICD-9 Finland
Non-toxic nodular goitre, Non-toxic multinodular goitre
+∞
307.7
559
*
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
10.0
307.7
410
428
24199
ICD-8 Finland
Non-toxic nodular goitre, Unspecified
+∞
307.7
1298
*
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
497.4
307.7
471
10
E04.0
ICD-10 Finland
Nontoxic diffuse goitre
219.4
307.7
536
26
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
27.4
307.7
549
213
T81
ICPC
Goitre
44.3
307.7
229
53
D34
ICD-10 Finland
Benign neoplasm of thyroid gland
20.0
303.6
234
120
E04
ICD-10 Finland
Other nontoxic goitre
36.7
289.7
180
50
24110
ICD-8 Finland
Non-toxic nodular goitre, Sporadic
+∞
286.0
273
*
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
955.4
284.8
278
*
106
Kela drug reimbursment
Hypoparathyroidism
66.7
228.4
125
19
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
86.1
225.6
119
14
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
501.5
198.4
197
*
BAA25
NOMESCO Finland
Bilateral partial excision of thyroid gland
+∞
174.5
167
*
BA1AE, ,
SPAT
9.4
154.1
185
201
T72
ICPC
Benign neoplasm thyroid
21.2
142.9
107
51
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.0
134.9
653
2318
E83.51
ICD-10 Finland
Hypocalcemia
12.6
132.5
130
105
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
131.5
3879
27499
A11CC03
ATC
alfacalcidol; systemic
4.9
128.1
289
608
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
23.5
119.6
86
37
JN5PN
NOMESCO Finland
Isotope imaging of secondary neoplasms of thyroid origin
1164.1
118.0
115
*
BAA50
NOMESCO Finland
Lobectomy and resection of contralateral lobe of thyroid gland
303.9
117.4
119
*
24100
ICD-8 Finland
Non-toxic nodular goitre, Endemic
+∞
115.9
111
*
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
3.2
113.1
476
1556
T85
ICPC
Hyperthyroidism/thyrotoxicosis
24.3
108.5
77
32
E07.9
ICD-10 Finland
Disorder of thyroid, unspecified
22.5
104.0
76
34
A11CC02
ATC
dihydrotachysterol; oral
24.1
103.9
74
31
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
5.2
102.1
212
415
R13
ICD-10 Finland
Dysphagia
2.4
101.7
739
3205
C73
ICD-10 Finland
Malignant neoplasm of thyroid gland
55.3
96.9
55
10
E06.3
ICD-10 Finland
Autoimmune thyroiditis
20.7
95.2
72
35
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
93.9
2323
15372
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
89.8
2054
13281
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
4.9
88.4
197
410
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
86.2
3285
24076
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
431.9
86.2
86
*
C73.92
ICD-10 Finland
Follicular carcinoma of the thyroid gland
212.0
81.4
84
*
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
3.8
80.3
249
668
2419X
ICD-9 Finland
Non-toxic nodular goitre, Unspecified non-toxic nodular goitre
+∞
79.3
76
*
E06.1
ICD-10 Finland
Subacute thyroiditis
+∞
69.9
67
*
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
5.0
69.6
152
311
N02BE01
ATC
paracetamol; systemic, rectal
1.9
67.5
7937
72887
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
+∞
66.7
64
*
GB1AA
NOMESCO Finland
Tracheal X-ray examination
139.1
65.0
69
5
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
64.6
1840
12435
A02BC05
ATC
esomeprazole; systemic
1.5
63.9
3635
28471
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
63.7
2476
17944
R03AC02
ATC
salbutamol; inhalant
1.5
63.6
4638
38080
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
10.7
63.6
69
65
GD6AD
NOMESCO Finland
CT of chest and neck
9.7
62.7
73
76
R49.01
ICD-10 Finland
Functional dysphonia
2.7
62.5
341
1283
BBA70
NOMESCO Finland
Implantation or transplantation of parathyroid gland
29.4
61.6
41
14
G47.3
ICD-10 Finland
Sleep apnoea
1.6
60.4
1552
10211
R06.0
ICD-10 Finland
Dyspnoea
1.5
60.3
2360
17090
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
592.2
59.8
59
*
JN5AQ
NOMESCO Finland
SPECT of thyroid metastasis with low-dose CT
+∞
59.4
57
*
EP1AE, ,
SPAT
3.8
57.0
178
480
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.8
56.4
295
1086
2410A
ICD-9 Finland
Non-toxic nodular goitre, Non-toxic uninodular goitre
+∞
56.3
54
*
WX402
NOMESCO Finland
General anaesthesia
1.5
51.6
1709
11877
2506
FHL
Thyroidectomy
174.3
49.9
52
*
C73.99
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland), other or unspecified histology
92.3
49.8
55
6
8330/3-C73.9
ICD-O-3
Follicular carcinoma, NOS, of thyroid gland
108.7
49.8
54
5
C07AB07
ATC
bisoprolol; oral
1.4
49.8
4189
34661
TBA20
NOMESCO Finland
Aspiration cytology of thyroid gland
490.7
49.4
49
*
R01AD09
ATC
mometasone; nasal
1.4
49.2
3675
29782
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
48.6
3016
23659
ZXA05
NOMESCO Finland
Left side
1.5
48.4
2236
16611
J01DB01
ATC
cefalexin; oral
1.5
47.7
6947
62965
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
47.5
2495
18976
4CJ01, ,
NOMESCO Finland
470.4
47.4
47
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
47.1
3829
31395
ZXA00
NOMESCO Finland
Right side
1.4
46.9
2384
18010
E05.1
ICD-10 Finland
Thyrotoxicosis with toxic single thyroid nodule
+∞
46.9
45
*
BA2AT
NOMESCO Finland
Biopsy of thyroid with ultrasound quidance
18.6
46.5
37
20
E03.2
ICD-10 Finland
Hypothyroidism due to medicaments and other exogenous substances
236.2
46.0
47
*
C73.90
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland) without histology
74.8
46.0
52
7
DQE10
NOMESCO Finland
Injection of foreign material into vocal cord
9.1
45.9
56
62
GD6BD
NOMESCO Finland
Extensive CT of chest and neck
11.9
44.5
45
38
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
5.2
43.9
89
171
E89.0
ICD-10 Finland
Postprocedural hypothyroidism
+∞
43.8
42
*
M79.6
ICD-10 Finland
Pain in limb
1.4
43.5
3568
29172
8341/3-C73.9
ICD-O-3
Papillary microcarcinoma of thyroid gland
429.8
43.2
43
*
R07.0
ICD-10 Finland
Pain in throat
1.9
42.2
526
2795
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
41.6
1861
13676
R49.08
ICD-10 Finland
Other specified dysphonia
2.7
40.3
221
834
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
40.2
2382
18400
T15
ICPC
THYROID LUMP/MASS
13.8
39.9
37
27
SPAT1153
SPAT
Removal of sutures
1.4
39.6
2658
20954
R21
ICPC
Throat symptom/complaint
1.5
39.4
1420
9986
A02BC02
ATC
pantoprazole; systemic
1.4
38.7
5846
52087
ZX114
NOMESCO Finland
Intramuscular
3.5
38.7
134
388
J01AA02
ATC
doxycycline; systemic
1.4
38.3
6682
60866
S18
ICPC
Laceration/cut
1.3
38.0
3760
31425
R53
ICD-10 Finland
Malaise and fatigue
1.4
37.8
1924
14445
J01FA10
ATC
azithromycin; systemic
1.3
37.3
4561
39272
A12AA04
ATC
calcium carbonate; oral
3.5
37.2
128
369
J01FA06
ATC
roxithromycin; oral
1.3
37.1
3330
27401
E21.0
ICD-10 Finland
Primary hyperparathyroidism
2.6
36.1
204
782
BAA30
NOMESCO Finland
Excision of thyroid isthmus
44.2
35.9
44
10
UJF32
NOMESCO Finland
Coloscopy
1.4
35.2
2221
17261
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
35.0
1871
14143
SPAT1263
SPAT
Sampling
1.3
34.7
3364
27909
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
34.7
2823
22828
24099
ICD-8 Finland
Simple goitre, Unspecified
+∞
34.4
33
*
BA1NN
NOMESCO Finland
I-131 dose capsel measurement
+∞
34.4
33
*
M03BX02
ATC
tizanidine; oral
1.3
34.1
4985
43768
BWD00
NOMESCO Finland
Reoperation for deep haemorrhage in endocrine surgery
76.4
33.8
38
5
E20.8
ICD-10 Finland
Other hypoparathyroidism
175.7
33.7
35
*
ZXA10
NOMESCO Finland
Bilateral
1.4
33.3
1615
11982
Z50.5
ICD-10 Finland
Speech therapy
3.4
33.3
118
347
T71
ICPC
Malignant neoplasm thyroid
328.4
32.9
33
*
R42
ICD-10 Finland
Dizziness and giddiness
1.4
32.7
2025
15659
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
32.4
1436
10477
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
32.2
5257
46679
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
32.1
3167
26255
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
32.0
1540
11401
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
31.9
844
5530
R02
ICPC
Shortness of breath/dyspnoea
1.5
31.8
1064
7342
B01AB05
ATC
enoxaparin; parenteral
1.3
31.3
2716
22090
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
31.2
3383
28385
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
31.2
3995
34279
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.6
31.0
814
5325
M54.5
ICD-10 Finland
Low back pain
1.3
31.0
2814
23030
EP2AT
NOMESCO Finland
Neck soft tissue cytology with ultrasound guidance
7.1
30.9
46
65
A02BC03
ATC
lansoprazole; oral
1.3
30.9
2423
19412
N02AX02
ATC
tramadol; systemic, rectal
1.3
30.6
3417
28758
G44.2
ICD-10 Finland
Tension-type headache
1.5
30.2
1106
7771
A02BC04
ATC
rabeprazole; oral
1.6
29.9
706
4500
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.5
29.8
999
6892
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
29.5
2190
17374
19399
ICD-8 Finland
Malignant neoplasm of thyroid gland
+∞
29.2
28
*
N03AX12
ATC
[U] gabapentin; oral
1.4
29.0
1323
9685
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
28.6
3050
25442
E66.01
ICD-10 Finland
Obesity due to excess calories
1.7
28.6
584
3589
R03DC03
ATC
montelukast; oral
1.4
28.3
1295
9481
24210
ICD-8 Finland
Thyrotoxicosis with or without goitre, Toxic nodular goitre
9.5
27.9
33
35
J37.0
ICD-10 Finland
Chronic laryngitis
2.1
27.4
266
1292
R01AD12
ATC
fluticasone furoate; nasal
1.3
27.1
2237
17987
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
26.9
1440
10830
R01AD58
ATC
fluticasone, combinations; nasal
1.4
26.5
1687
13041
ZSB00
NOMESCO Finland
Procedure related to previous procedure classified in chapter B
29.3
26.2
35
12
J01DA01
ATC
[U] cefalexin
1.3
26.2
4975
44440
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
26.2
1377
10317
H02AB06
ATC
prednisolone; systemic
1.3
26.0
3786
32745
M25.5
ICD-10 Finland
Pain in joint
1.3
25.9
2490
20426
BAA99
NOMESCO Finland
Other operation on thyroid gland
72.9
25.8
29
*
UKC02
NOMESCO Finland
Cystoscopy
1.4
25.4
1042
7469
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.6
25.4
619
3974
A02BA02
ATC
ranitidine; systemic
1.4
25.2
1577
12149
2409X
ICD-9 Finland
Simple and unspecified goitre, Goitre, unspecified
22.6
25.1
36
16
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
25.0
24
*
R51.80
ICD-10 Finland
Headache
1.4
24.9
1116
8125
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
24.7
3094
26217
S04
ICPC
Lump/swelling localized
1.5
24.7
778
5289
WX704
NOMESCO Finland
Intubation
1.6
24.7
612
3944
R5140
NOMESCO Finland
Monitoring the use of the aid
1.5
24.4
693
4607
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
24.4
2942
24806
A02BC01
ATC
omeprazole; systemic
1.3
24.3
2207
17932
E06.9
ICD-10 Finland
Thyroiditis, unspecified
22.0
24.3
35
16
A12AA06
ATC
calcium lactate gluconate; oral
34.6
24.2
31
9
N03AX16
ATC
[U] pregabalin
1.3
24.1
1870
14862
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
24.1
5496
49930
24599
ICD-8 Finland
Thyroiditis, Unspecified
+∞
24.0
23
*
2440A
ICD-9 Finland
Acquired hypothyroidism, Postsurgical hypothyroidism
240.6
23.6
24
*
SPAT1301
SPAT
No procedures
1.3
23.6
2484
20562
R49.8
ICD-10 Finland
Other and unspecified voice disturbances
2.9
23.6
110
382
M02AA07
ATC
piroxicam; topical
1.3
23.5
3088
26275
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.3
23.2
1836
14624
SPAT1325
SPAT
Vaccination
1.3
23.1
2737
22984
Z71.8
ICD-10 Finland
Other specified counselling
1.3
23.1
2304
18932
C07AA05
ATC
propranolol; systemic
1.4
23.1
1441
11080
8340/3-C73.9
ICD-O-3
Papillary carcinoma, follicular variant of thyroid gland
+∞
22.9
22
*
N06AX21
ATC
duloxetine; oral
1.5
22.7
872
6164
SPAT1058
SPAT
PEF monitoring instruction
1.5
22.7
651
4334
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.5
22.7
648
4310
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
22.5
2087
16974
J01MA02
ATC
ciprofloxacin; systemic
1.3
22.2
2963
25208
BBA20
NOMESCO Finland
Exploration of parathyroid gland
5.2
22.1
45
87
R00.2
ICD-10 Finland
Palpitations
1.6
22.1
602
3961
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
22.1
2290
18890
E20.9
ICD-10 Finland
Hypoparathyroidism, unspecified
19.5
22.1
33
17
XKD00
NOMESCO Finland
Uroflowmetry
1.5
22.1
716
4895
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
21.9
3434
29752
C08CA01
ATC
amlodipine; oral
1.3
21.7
3146
27007
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.4
21.7
1320
10101
ZXE20
NOMESCO Finland
More than three and less than five hours
1.4
21.6
976
7107
E03.8
ICD-10 Finland
Other specified hypothyroidism
220.5
21.6
22
*
AA1AD
NOMESCO Finland
CT of head and brain
1.3
21.5
2145
17602
GAB20
NOMESCO Finland
Median sternotomy
31.2
21.4
28
9
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
21.2
3862
33982
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
21.0
2350
19545
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.4
21.0
1202
9109
SPAT1312
SPAT
General health counselling
1.3
20.9
2355
19604
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.3
20.9
1599
12655
J01FA09
ATC
clarithromycin; systemic
1.3
20.9
2371
19758
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.4
20.6
955
6985
L03
ICPC
Low back symptom/complaint
1.3
20.6
2144
17670
R4130
NOMESCO Finland
Speech therapy
2.1
20.6
184
868
C07AB02
ATC
metoprolol; systemic
1.3
20.5
1606
12747
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.3
20.4
1876
15213
SPAT1310
SPAT
Counselling related to known health issue
1.3
20.3
2419
20258
R01AD08
ATC
fluticasone; nasal
1.3
20.3
2087
17168
C09CA01
ATC
losartan; oral
1.3
20.2
2070
17021
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.2
20.1
5151
46894
J02AC01
ATC
fluconazole; systemic
1.2
20.0
3403
29660
UDQ02
NOMESCO Finland
Direct laryngoscopy
3.4
19.9
70
206
E05.89
ICD-10 Finland
Other thyrotoxicosis
+∞
19.8
19
*
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
19.8
1827
14816
E66.8
ICD-10 Finland
Other obesity
1.7
19.7
342
2012
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
19.7
3115
26927
M01AE02
ATC
naproxen; oral, rectal
1.2
19.3
4351
39009
R52.9
ICD-10 Finland
Pain, unspecified
1.5
19.3
738
5211
M54.6
ICD-10 Finland
Pain in thoracic spine
1.6
19.2
521
3424
H04.10
ICD-10 Finland
Dry eye syndrome
1.4
19.2
918
6745
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.6
19.2
448
2846
L17
ICPC
Foot/toe symptom/complaint
1.3
19.1
2280
19077
Z01.7
ICD-10 Finland
Laboratory examination
1.4
19.0
1056
7953
C03CA01
ATC
furosemide; systemic
1.3
19.0
2428
20473
I49.3
ICD-10 Finland
Ventricular premature depolarization
1.5
18.9
527
3485
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.3
18.7
1537
12261
C05AA08
ATC
fluocortolone; rectal, topical
1.4
18.6
1035
7795
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
18.6
1638
13187
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.3
18.6
1433
11331
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
2.7
18.6
98
365
SFA10
NOMESCO Finland
One-surface restoration
1.2
18.6
4000
35642
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
18.4
2053
17028
R04.2
ICD-10 Finland
Haemoptysis
1.9
18.3
217
1135
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.2
18.3
3221
28095
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
2.8
18.3
88
312
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
18.3
3224
28125
WZC30
NOMESCO Finland
Teaching
1.4
18.3
1136
8704
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.4
18.3
820
5958
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.2
18.2
4112
36782
M79.1
ICD-10 Finland
Myalgia
1.4
18.2
1039
7860
R20.2
ICD-10 Finland
Paraesthesia of skin
1.6
18.1
484
3173
J01EA01
ATC
trimethoprim; systemic
1.3
18.1
2387
20177
SPAT1260
SPAT
Consultation of another employee
1.3
18.0
1345
10583
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
2.5
18.0
111
447
R49.03
ICD-10 Finland
Atrophic dysphonia
2.6
18.0
99
377
J20
ICD-10 Finland
Acute bronchitis
1.4
18.0
743
5320
R49.09
ICD-10 Finland
Unspecified dysphonia
2.7
17.9
97
366
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.3
17.9
1878
15447
Z3231
NOMESCO Finland
Registered nurse
1.3
17.8
2010
16677
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
17.8
1586
12782
M01AH05
ATC
etoricoxib; oral
1.2
17.8
4854
44206
R60.0
ICD-10 Finland
Localized oedema
1.4
17.7
973
7311
C10AA07
ATC
rosuvastatin; oral
1.2
17.7
2437
20685
E05.4
ICD-10 Finland
Thyrotoxicosis factitia
+∞
17.7
17
*
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
17.7
2057
17131
N06AX11
ATC
mirtazapine; oral
1.2
17.6
2599
22228
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
17.6
4923
44919
R05
ICPC
Cough
1.3
17.4
1847
15210
L01
ICPC
Neck symptom/complaint
1.3
17.4
1165
9026
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
17.3
1578
12750
J01CA04
ATC
amoxicillin; systemic
1.2
17.3
6526
61332
L15
ICPC
Knee symptom/complaint
1.3
17.2
1926
15954
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.4
17.2
994
7527
SPAT1097
SPAT
Recording of ECG
1.3
17.1
1127
8706
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
1.6
17.1
383
2408
K80
ICPC
Cardiac arrhythmia NOS
1.4
17.0
653
4609
R06AE07
ATC
cetirizine; oral
1.2
17.0
3438
30346
RP210, ,
NOMESCO Finland
6.6
17.0
27
41
Z01.2
ICD-10 Finland
Dental examination
1.2
17.0
3313
29138
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.3
17.0
1236
9687
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.5
16.7
568
3916
A01AB09
ATC
miconazole; local oral
1.4
16.7
699
5017
R05
ICD-10 Finland
Cough
1.3
16.6
1642
13396
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.4
16.5
769
5620
R06.5
ICD-10 Finland
Mouth breathing
1.5
16.5
488
3269
R03BA05
ATC
fluticasone; inhalant
1.3
16.5
1323
10502
K30
ICD-10 Finland
Functional dyspepsia
1.4
16.5
850
6321
XF402
NOMESCO Finland
ECG with work load test
1.4
16.4
749
5454
E83.50
ICD-10 Finland
Hypercalcemia
2.3
16.4
120
522
M01AB05
ATC
diclofenac; systemic, rectal
1.2
16.4
5224
48099
H02AB09
ATC
hydrocortisone; systemic
2.3
16.2
125
556
R03AC03
ATC
terbutaline; inhalant
1.3
16.2
1049
8080
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.3
16.1
1681
13794
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.4
16.1
905
6823
M01AC06
ATC
meloxicam; systemic, rectal
1.2
16.1
2991
26145
D01
ICPC
Abdominal pain/cramps general
1.4
15.9
823
6120
R01BA52
ATC
pseudoephedrine, combinations; oral
1.2
15.9
2404
20563
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.5
15.9
495
3352
G04CB01
ATC
finasteride; oral
1.6
15.9
380
2427
A04
ICPC
Weakness/tiredness general
1.3
15.9
1075
8332
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.5
15.9
460
3069
I83.9
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
1.4
15.8
885
6664
M01AX17
ATC
nimesulide; oral
1.3
15.8
1950
16312
M70.6
ICD-10 Finland
Trochanteric bursitis
1.3
15.8
1209
9531
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
1.7
15.8
263
1529
B02AA02
ATC
tranexamic acid; systemic
1.3
15.8
1143
8946
M48.0
ICD-10 Finland
Spinal stenosis
1.3
15.7
974
7453
P01AB01
ATC
metronidazole; oral, rectal
1.2
15.6
3219
28392
C08CA13
ATC
lercanidipine; oral
1.3
15.6
1157
9081
24400
ICD-8 Finland
Myxoedema, (hypothyreosis) post therapiam
+∞
15.6
15
*
R06AX27
ATC
desloratadine; oral
1.2
15.6
1982
16633
J01FF01
ATC
clindamycin; systemic
1.2
15.6
1952
16358
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
1.4
15.5
927
7057
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.3
15.4
1425
11518
WX110
NOMESCO Finland
Infiltration anesthesia
1.2
15.4
5412
50138
R03BA08
ATC
ciclesonide; inhalant
1.4
15.4
631
4509
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.3
15.4
1567
12819
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.4
15.3
714
5220
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.3
15.3
940
7182
F45.8
ICD-10 Finland
Other somatoform disorders
1.5
15.3
412
2706
R96
ICPC
Asthma
1.4
15.3
735
5402
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.5
15.2
530
3672
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
1.6
15.2
337
2116
H01
ICPC
Ear pain/earache
1.4
15.2
759
5615
J31.0
ICD-10 Finland
Chronic rhinitis
1.5
15.1
558
3912
E07.89
ICD-10 Finland
Other specified disorders of thyroid
20.0
15.1
22
11
N06AX16
ATC
venlafaxine; oral
1.3
15.1
906
6899
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
1.3
15.1
1045
8126
C09CA06
ATC
candesartan; oral
1.2
15.0
1817
15158
T90
ICPC
Diabetes non-insulin dependent
1.3
14.9
1660
13713
WZA90
NOMESCO Finland
Other medical or dental certificate
1.3
14.9
1616
13312
A01
ICPC
Pain general/multiple sites
1.4
14.9
701
5133
R12
ICD-10 Finland
Heartburn
1.4
14.7
578
4098
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.4
14.6
579
4111
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
14.5
7351
70376
D21
ICPC
Swallowing problem
2.3
14.5
111
493
N05BA04
ATC
oxazepam; oral
1.2
14.5
1979
16718
N02BF01
ATC
gabapentin; oral
1.4
14.5
587
4185
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
1.4
14.4
849
6441
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
2.5
14.4
90
365
XF404
NOMESCO Finland
Ambulatory ECG
1.4
14.4
626
4518
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.4
14.4
663
4833
205
Kela drug reimbursment
Chronic hypertension
1.2
14.4
2068
17566
E66.00
ICD-10 Finland
Metabolic syndrome
1.6
14.3
326
2061
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.3
14.3
1638
13574
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.3
14.2
1227
9820
R05FB02
ATC
cough suppressants and expectorants; systemic
1.2
14.2
3032
26764
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.4
14.2
624
4513
L02
ICPC
Back symptom/complaint
1.4
14.2
688
5060
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
1.7
14.2
281
1714
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.4
14.2
662
4838
T78.4
ICD-10 Finland
Allergy, unspecified
1.6
14.1
301
1872
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.3
14.1
905
6956
C09DA01
ATC
losartan and diuretics; oral
1.4
14.1
824
6247
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.6
14.0
310
1944
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.5
14.0
423
2848
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
14.0
3372
30089
WX725
NOMESCO Finland
Noninvasive ventilation
1.6
14.0
364
2374
M01AH01
ATC
celecoxib; oral
1.3
13.9
1445
11830
D17.1
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
1.7
13.9
233
1359
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.4
13.8
805
6096
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
1.6
13.8
320
2030
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.3
13.8
834
6353
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.3
13.8
1482
12184
SFA20
NOMESCO Finland
Two-surface restoration
1.2
13.8
4192
38160
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.3
13.8
979
7635
E06.0
ICD-10 Finland
Acute thyroiditis
20.0
13.8
20
10
BA3AT, ,
SPAT
11.4
13.7
25
22
R03BA02
ATC
budesonide; inhalant
1.3
13.7
1306
10581
M79.7
ICD-10 Finland
Fibromyalgia
1.7
13.7
258
1554
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.4
13.7
546
3883
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
2.1
13.7
129
624
J46
ICD-10 Finland
Status asthmaticus
1.8
13.6
216
1240
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.3
13.6
1274
10301
G04CA02
ATC
tamsulosin; oral
1.3
13.6
811
6166
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
1.9
13.5
179
973
D35.1
ICD-10 Finland
Benign neoplasm: Parathyroid gland
4.3
13.5
34
79
R94.6
ICD-10 Finland
Abnormal results of thyroid function studies
4.3
13.5
34
79
JN5SN, ,
NOMESCO Finland
+∞
13.5
13
*
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.3
13.5
801
6083
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.3
13.5
1046
8252
UDC00
NOMESCO Finland
Ear microscopy
1.5
13.5
493
3449
R74
ICPC
Upper respiratory infection acute
1.2
13.5
2023
17244
E06.5
ICD-10 Finland
Other chronic thyroiditis
140.2
13.4
14
*
1930A
ICD-9 Finland
Malignant neoplasm of thyroid gland[CARCINOMA PAPILLARE THYREOIDEAE]
140.2
13.4
14
*
D11.0
ICD-10 Finland
Benign neoplasm: Parotid gland
2.1
13.4
125
602
QX3LT
NOMESCO Finland
Subcutaneous sclerotherapy
12.8
13.4
23
18
R03BB04
ATC
tiotropium bromide; inhalant
1.4
13.4
663
4896
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.2
13.3
2212
19040
C10AA05
ATC
atorvastatin; oral
1.2
13.3
3182
28332
F29
ICPC
Eye symptom/complaint other
1.4
13.3
675
5001
A98
ICPC
Health maint/preventive medicine
1.4
13.3
8255
80418
A07AA02
ATC
nystatin; oral
1.5
13.3
465
3227
B01AF02
ATC
apixaban; oral
1.3
13.2
959
7499
R03BA01
ATC
beclometasone; inhalant
1.3
13.2
1055
8357
Z3226
NOMESCO Finland
Physiotherapist
1.3
13.2
1338
10919
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.4
13.1
672
4991
ZXE00
NOMESCO Finland
One hour or less
1.2
13.1
2902
25663
A11
ICPC
Chest pain NOS
1.4
13.1
605
4417
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.3
13.0
1134
9080
R51.81
ICD-10 Finland
Facial pain NOS
1.9
13.0
174
949
D06
ICPC
Abdominal pain localized other
1.4
13.0
617
4520
L82
ICD-10 Finland
Seborrhoeic keratosis
1.3
13.0
1447
11933
M79.0
ICD-10 Finland
Rheumatism, unspecified
1.6
13.0
275
1708
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
1.4
13.0
582
4226
R07.3
ICD-10 Finland
Other chest pain
1.4
12.9
733
5528
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.4
12.9
718
5398
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.3
12.9
779
5931
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.4
12.9
698
5229
A10BJ06
ATC
semaglutide; parenteral
1.6
12.8
274
1705
A10BA02
ATC
metformin; oral
1.2
12.8
1951
16640
207
Kela drug reimbursment
Chronic arrhythmias
1.3
12.7
1164
9378
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.3
12.7
955
7500
S29
ICPC
Skin symptom/complaint other
1.3
12.7
1418
11697
K02.1
ICD-10 Finland
Caries of dentine
1.2
12.7
4087
37278
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.3
12.7
748
5676
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.4
12.7
525
3760
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.5
12.6
417
2860
D25.9
ICD-10 Finland
Leiomyoma of uterus, unspecified
1.4
12.6
722
5455
R60.9
ICD-10 Finland
Oedema, unspecified
1.5
12.5
400
2726
BB1BQ
NOMESCO Finland
Extensive scintigraphy of parathyroid gland, 2 isotopes, SPECT and low-dose CT
3.7
12.5
38
102
E03.4
ICD-10 Finland
Atrophy of thyroid (acquired)
+∞
12.5
12
*
8290/3-C73.9
ICD-O-3
Oxyphilic adenocarcinoma of thyroid gland
+∞
12.5
12
*
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.3
12.5
1289
10540
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.4
12.4
490
3478
L28
ICPC
Limited function/disability (L)
1.2
12.4
1410
11654
A06AD11
ATC
lactulose; oral
1.3
12.4
1066
8522
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
1.6
12.4
293
1870
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.3
12.4
1381
11390
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
1.8
12.3
182
1025
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.5
12.3
411
2828
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.6
12.2
308
1996
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.3
12.2
1034
8252
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.3
12.2
1086
8722
A03FA02
ATC
cisapride; oral, rectal
1.4
12.1
579
4248
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.4
12.1
562
4104
RL210, ,
NOMESCO Finland
3.5
12.1
40
114
M01AX05
ATC
glucosamine; oral
1.2
12.1
1772
15046
D44.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Adrenal gland
2.3
12.0
89
391
A08
ICPC
Swelling
1.5
12.0
392
2683
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.5
12.0
327
2157
J38.4
ICD-10 Finland
Oedema of larynx
3.0
11.9
50
165
S21
ICPC
Skin texture symptom/complaint
1.3
11.9
1038
8307
R03AK07
ATC
formoterol and budesonide; inhalant
1.2
11.9
1409
11692
F51.0
ICD-10 Finland
Nonorganic insomnia
1.3
11.8
998
7956
J01DA09
ATC
[U] cefadroxil
1.2
11.8
1854
15849
21899
ICD-8 Finland
Uterine fibroma
1.4
11.8
439
3085
J38.7
ICD-10 Finland
Other diseases of larynx
3.0
11.7
51
172
6481B
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Thyroid dysfunction[HYPOTHYREOSIS IN GRAVIDITATE]
65.0
11.6
13
*
B01AA03
ATC
warfarin; systemic
1.2
11.6
1301
10732
N64.4
ICD-10 Finland
Mastodynia
1.6
11.5
233
1431
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.3
11.5
839
6558
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.4
11.5
554
4073
BA4KT
NOMESCO Finland
Sclerotherapy of thyroid
+∞
11.5
11
*
24209
ICD-8 Finland
Thyrotoxicosis with or without goitre, Cum struma diffuse NUD
+∞
11.5
11
*
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
3.2
11.5
43
133
D25.1
ICD-10 Finland
Intramural leiomyoma of uterus
1.4
11.4
477
3420
TDM10
NOMESCO Finland
Puncture of maxillary antrum
1.6
11.4
235
1451
C03DA01
ATC
spironolactone; oral
1.3
11.3
841
6591
J45
ICD-10 Finland
Asthma
1.3
11.3
729
5601
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.4
11.3
540
3961
N06AA09
ATC
amitriptyline; systemic
1.3
11.3
733
5641
R4110, ,
SPAT
1.4
11.3
637
4802
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.4
11.3
468
3354
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.4
11.2
559
4130
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
1.4
11.2
418
2936
R11
ICD-10 Finland
Nausea and vomiting
1.4
11.2
610
4571
K59.09
ICD-10 Finland
Constipation, unspecified
1.4
11.1
471
3386
A02BA04
ATC
nizatidine; systemic
1.4
11.1
555
4103
S82
ICPC
Naevus/mole
1.3
11.1
938
7477
K11.2
ICD-10 Finland
Sialoadenitis
1.6
11.1
221
1353
J01FA15
ATC
telithromycin; oral
1.3
11.1
662
5032
R00
ICD-10 Finland
Abnormalities of heart beat
3.4
11.1
38
111
N01
ICPC
Headache
1.4
11.0
626
4721
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.3
11.0
834
6554
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.3
11.0
825
6478
103
Kela drug reimbursment
Diabetes, insulin-treated
1.2
11.0
1778
15229
N40
ICD-10 Finland
Hyperplasia of prostate
1.3
11.0
670
5111
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.2
10.9
1268
10493
E21.2
ICD-10 Finland
Other hyperparathyroidism
3.2
10.9
42
132
R03AK08
ATC
formoterol and beclometasone; inhalant
1.5
10.9
297
1960
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
2.0
10.9
117
596
R49.0
ICD-10 Finland
Dysphonia
1.9
10.9
137
736
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.3
10.8
958
7679
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.3
10.8
770
6003
J35.0
ICD-10 Finland
Chronic tonsillitis
1.6
10.8
240
1512
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.3
10.7
986
7941
M01AH02
ATC
rofecoxib; oral
1.3
10.7
1014
8196
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.2
10.7
1376
11514
R31
ICD-10 Finland
Unspecified haematuria
1.4
10.7
544
4036
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
1.6
10.7
263
1697
SPAT1212
SPAT
Extensive examination of musculoskeletal system
1.4
10.6
544
4037
-, ,
ICD-10 Finland
1.8
10.6
161
915
J01DA06
ATC
[U] cefuroxime
1.3
10.6
995
8034
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
1.8
10.6
141
771
A99
ICPC
Disease/condition unspecnature/site
1.3
10.5
638
4862
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.4
10.5
433
3102
J39.2
ICD-10 Finland
Other diseases of pharynx
2.3
10.4
73
314
C739, ,
ICD-10 Finland
110.2
10.4
11
*
E03.1
ICD-10 Finland
Congenital hypothyroidism without goitre
110.2
10.4
11
*
24200
ICD-8 Finland
Thyrotoxicosis with or without goitre, Cum struma diffusa et exophthalmo. Morbus Basedowi
+∞
10.4
10
*
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.2
10.4
1856
16030
A10BH05
ATC
linagliptin; oral
1.5
10.4
331
2258
24409
ICD-8 Finland
Myxoedema, (hypothyreosis) NUD
16.0
10.3
16
10
SPAT1211
SPAT
Application of soft bandage
1.3
10.3
604
4577
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.2
10.2
3185
28808
L16
ICPC
Ankle symptom/complaint
1.3
10.2
776
6102
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
1.6
10.2
216
1345
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
1.8
10.1
133
724
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.2
10.1
1244
10352
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
1.5
10.1
262
1710
H92.0
ICD-10 Finland
Otalgia
1.4
10.1
380
2676
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.3
10.1
709
5516
L72.1
ICD-10 Finland
Trichilemmal cyst
1.4
10.1
425
3055
C08CA02
ATC
felodipine; oral
1.3
10.1
697
5411
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
1.5
10.0
356
2479
XQ845
NOMESCO Finland
Dermatoscopy
1.9
10.0
127
684
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.2
10.0
1244
10365
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.2
10.0
2808
25185
H93.1
ICD-10 Finland
Tinnitus
1.4
10.0
449
3263
SPAT1216
SPAT
Assessment of functional ability
1.2
10.0
1214
10091
SPAT1257
SPAT
Teaching of medicine inhalation technique
1.6
10.0
244
1572
SAA03
NOMESCO Finland
Extended examination of mouth
1.2
10.0
2626
23434
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.2
10.0
1867
16190
R01AD01
ATC
beclometasone; nasal
1.3
9.9
1051
8606
GD1AD
NOMESCO Finland
Thorax CT examination
1.5
9.9
354
2470
L90
ICPC
Osteoarthrosis of knee
1.4
9.9
534
3999
ZXD20
NOMESCO Finland
Day surgery
1.3
9.9
925
7467
R52.2
ICD-10 Finland
Other chronic pain
1.6
9.8
245
1585
SPAT1281
SPAT
Other administrative function
1.4
9.8
499
3699
R29
ICPC
Respiratory symptom/complaint other
1.4
9.8
418
3010
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.2
9.8
1777
15364
H53.1
ICD-10 Finland
Subjective visual disturbances
1.4
9.7
473
3482
H13
ICPC
Plugged feeling ear
1.2
9.7
1358
11449
L86
ICPC
Back syndrome with radiating pain
1.4
9.7
432
3134
SPAT1336
SPAT
Request for examination
1.6
9.7
243
1575
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
1.9
9.7
116
614
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.5
9.6
319
2193
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.2
9.6
1669
14365
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
2.1
9.6
85
403
J38.3
ICD-10 Finland
Other diseases of vocal cords
2.3
9.6
71
313
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.3
9.6
588
4487
R51
ICD-10 Finland
Headache
1.5
9.6
325
2245
S01
ICPC
Pain/tenderness of skin
1.5
9.6
301
2048
C01DA14
ATC
isosorbide mononitrate; oral
1.2
9.6
1024
8392
M47.82
ICD-10 Finland
Other spondylosis, cervical region
1.5
9.6
279
1869
L13
ICPC
Hip symptom/complaint
1.2
9.6
1518
12957
Z00.0
ICD-10 Finland
General medical examination
1.2
9.6
1323
11144
A10BK03
ATC
empagliflozin; oral
1.3
9.5
571
4343
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.3
9.5
850
6820
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.3
9.5
826
6606
M54.2
ICD-10 Finland
Cervicalgia
1.4
9.5
504
3764
P06
ICPC
Sleep disturbance
1.3
9.5
700
5482
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.3
9.5
720
5662
N39.3
ICD-10 Finland
Stress incontinence
1.3
9.4
658
5113
A01AB04
ATC
amphotericin B; local oral
1.4
9.4
365
2585
K07.60
ICD-10 Finland
Snapping jaw
1.5
9.4
311
2138
A77
ICPC
Viral disease other/NOS
1.7
9.4
181
1101
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.3
9.4
775
6159
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
9.4
3091
28030
H062, E050,
ICD-10 Finland
+∞
9.4
9
*
2449X
ICD-9 Finland
Acquired hypothyroidism, Unspecified hypothyroidism
+∞
9.4
9
*
M14.5*E03.9
ICD-10 Finland
Arthropathy in hypothyroidism (E00-E03+)
+∞
9.4
9
*
J01
ICD-10 Finland
Acute sinusitis
1.5
9.4
334
2330
SPAT1229
SPAT
Assessment of need for aid
1.3
9.4
584
4469
Z71.9
ICD-10 Finland
Counselling, unspecified
1.4
9.3
448
3292
N17
ICPC
Vertigo/dizziness
1.3
9.3
931
7570
J45.1
ICD-10 Finland
Nonallergic asthma
1.4
9.3
491
3665
A60
ICPC
General and Unspecified, Result test/procedure
1.5
9.3
289
1963
EB1VA, ,
NOMESCO Finland
1.3
9.3
761
6042
J01CA08
ATC
pivmecillinam; oral
1.1
9.3
3924
36221
TPH07
NOMESCO Finland
Cathetrisation of artery
1.3
9.1
734
5816
D24
ICD-10 Finland
Benign neoplasm of breast
1.7
9.1
153
899
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
1.6
9.0
211
1346
Z25.1
ICD-10 Finland
Need for immunization against influenza
1.4
9.0
357
2538
D17.2
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
1.7
9.0
147
855
H57.1
ICD-10 Finland
Ocular pain
1.6
9.0
225
1458
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
1.4
9.0
444
3278
UJF30
NOMESCO Finland
Ileoscopy through colon
1.3
9.0
695
5476
M01AG02
ATC
tolfenamic acid; oral, rectal
1.2
9.0
1104
9186
T82
ICPC
Obesity
1.6
9.0
217
1397
M54
ICD-10 Finland
Dorsalgia
1.3
8.9
781
6250
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
2.6
8.9
51
200
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
1.4
8.9
401
2919
UJC01
NOMESCO Finland
Scopy of lower throat
2.4
8.9
59
249
WX723
NOMESCO Finland
CPAP therapy
1.6
8.8
202
1285
N06AB10
ATC
escitalopram; oral
1.2
8.8
1237
10434
SFA30
NOMESCO Finland
Three-surface restoration
1.2
8.8
2959
26845
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.3
8.8
672
5290
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
2.0
8.8
87
432
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
1.3
8.7
558
4284
N04BC05
ATC
pramipexole; oral
1.3
8.7
550
4215
L08
ICPC
Shoulder symptom/complaint
1.2
8.7
1571
13557
UDM02
NOMESCO Finland
Sinoscopy
1.8
8.7
127
716
Z2221
NOMESCO Finland
Medical doctor
1.2
8.7
1962
17261
E07
ICD-10 Finland
Other disorders of thyroid
14.0
8.7
14
10
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.3
8.6
668
5264
J34.2
ICD-10 Finland
Deviated nasal septum
1.5
8.6
231
1521
S01GX01
ATC
cromoglicic acid; ophthalmic
1.2
8.6
1408
12043
M47.9
ICD-10 Finland
Spondylosis, unspecified
1.5
8.6
223
1458
TQW40, ,
SPAT
1.3
8.6
476
3579
L60.0
ICD-10 Finland
Ingrowing nail
1.5
8.6
290
2003
G43.9
ICD-10 Finland
Migraine, unspecified
1.4
8.6
314
2202
SPAT1043
SPAT
Audiometry
1.3
8.6
746
5966
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
1.4
8.6
378
2741
SPAT1141
SPAT
Excision of skin or mucous membrane lesion
1.5
8.6
299
2079
E06
ICD-10 Finland
Thyroiditis
11.6
8.6
15
13
R04
ICPC
Breathing problem other
1.5
8.5
225
1477
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.3
8.5
563
4347
G54.0
ICD-10 Finland
Brachial plexus disorders
1.7
8.5
137
796
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.3
8.5
527
4032
L12
ICPC
Hand/finger symptom/complaint
1.2
8.5
1102
9219
C01BC04
ATC
flecainide; systemic
1.5
8.5
228
1504
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
1.4
8.5
377
2739
L29
ICPC
Musculoskeletal sympt/complt other
1.3
8.4
600
4676
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.4
8.4
449
3356
L91.0
ICD-10 Finland
Hypertrophic scar
2.1
8.4
79
384
WX780
NOMESCO Finland
Remote monitoring CPAP
1.6
8.4
210
1362
SPAT1254
SPAT
Administration of medicine
1.2
8.4
1017
8445
G04BD04
ATC
oxybutynin; oral, transdermal
1.4
8.4
414
3059
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.3
8.4
640
5036
SPAT1044
SPAT
Tympanometry
1.8
8.4
125
710
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.5
8.3
253
1711
24509
ICD-8 Finland
Thyroiditis, Unspecified
+∞
8.3
8
*
E8901, C7391,
ICD-10 Finland
+∞
8.3
8
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.3
8.3
660
5218
K02.0
ICD-10 Finland
Caries limited to enamel
1.2
8.3
1001
8310
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
1.5
8.3
264
1804
K21
ICD-10 Finland
Gastro-oesophageal reflux disease
1.4
8.3
369
2682
SFA00
NOMESCO Finland
Small restoration
1.2
8.2
894
7337
R09
ICPC
Sinus symptom/complaint
1.3
8.2
528
4059
G25.0
ICD-10 Finland
Essential tremor
1.6
8.2
172
1071
R00.0
ICD-10 Finland
Tachycardia, unspecified
1.5
8.2
256
1743
UJH02
NOMESCO Finland
Anoscopy
1.5
8.1
284
1975
M72.2
ICD-10 Finland
Plantar fascial fibromatosis
1.3
8.1
529
4074
R23
ICPC
Voice symptom/complaint
1.7
8.1
146
874
S06.0
ICD-10 Finland
Concussion
1.3
8.1
670
5325
D12
ICPC
Constipation
1.5
8.1
232
1551
E20
ICD-10 Finland
Hypoparathyroidism
33.4
8.1
10
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.3
8.1
770
6228
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.2
8.0
1014
8455
45499
ICD-8 Finland
Varicose veins of lower extremities, Other and unspecified, without ulcer
1.3
8.0
599
4702
M01AC01
ATC
piroxicam; systemic, rectal
1.2
8.0
962
7982
SCA01
NOMESCO Finland
Preventive oral health care, short
1.2
8.0
1785
15677
2260A
ICD-9 Finland
Benign neoplasm of thyroid gland[NEOPLASMA BENIGNUM GLANDULAE THYREOIDEAE]
3.8
8.0
23
60
R50.9
ICD-10 Finland
Fever, unspecified
1.2
8.0
892
7346
D11.70
ICD-10 Finland
Gland sublingual
3.4
7.9
27
79
D18.0
ICD-10 Finland
Haemangioma, any site
1.6
7.9
155
949
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
1.4
7.9
345
2498
XA402
NOMESCO Finland
ENMG
1.7
7.9
150
911
R06AE09
ATC
levocetirizine; oral
1.2
7.9
914
7551
SPAT1262
SPAT
Handing over of treatment supplies
1.2
7.9
1116
9410
SPAT1359
SPAT
Use of symptom diary
1.6
7.9
165
1027
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
2.0
7.9
81
408
SPAT1252
SPAT
Overall medication plan or its review
1.3
7.9
461
3497
C01CA24
ATC
epinephrine; parenteral
1.4
7.9
357
2603
SFA40
NOMESCO Finland
Restoration involving the entire crown of the tooth
1.2
7.8
1521
13203
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
2.6
7.8
44
172
EP1AT
NOMESCO Finland
Punction of soft tissue of neck with ultrasound guidance
10.8
7.8
14
13
A29
ICPC
General symptom/complaint other
1.2
7.8
873
7190
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
1.5
7.8
243
1655
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
1.4
7.8
378
2788
U07
ICPC
Urine symptom/complaint other
1.3
7.8
542
4216
XF600
NOMESCO Finland
Bloodpressure measurement
1.4
7.7
369
2713
R4110
NOMESCO Finland
Physiotherapy
1.2
7.7
2023
17984
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
1.3
7.7
448
3395
EMB10
NOMESCO Finland
Tonsillectomy
1.5
7.7
223
1495
23914
ICD-8 Finland
Neoplasm of unspecified nature of other and unspecified organs, Glandulae thyreoideae
15.0
7.7
12
8
R03AC13
ATC
formoterol; inhalant
1.4
7.7
340
2470
Z51.88
ICD-10 Finland
Other specified medical care
1.7
7.7
132
782
S22
ICPC
Nail symptom/complaint
1.3
7.6
414
3106
SPAT1202
SPAT
Intra-articular injection
1.5
7.6
236
1605
N63
ICD-10 Finland
Unspecified lump in breast
1.3
7.6
501
3866
SPAT1255
SPAT
Intravenous administration of medicine
1.3
7.6
411
3082
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
1.5
7.6
194
1267
WX720
NOMESCO Finland
Own respiration
1.4
7.6
284
2004
R25.1
ICD-10 Finland
Tremor, unspecified
1.5
7.6
191
1244
2180A
ICD-9 Finland
Uterine leiomyoma, Submucous leiomyoma of uterus
1.3
7.6
521
4046
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.4
7.5
366
2699
K08.80
ICD-10 Finland
Toothache NOS
1.3
7.5
516
4004
H60.3
ICD-10 Finland
Other infective otitis externa
1.7
7.5
130
771
TFP20
NOMESCO Finland
Cardiodefibrillation
1.3
7.5
413
3105
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
1.3
7.5
563
4422
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
2.1
7.5
65
308
K59.0
ICD-10 Finland
Constipation
1.4
7.5
369
2729
D07AB02
ATC
hydrocortisone butyrate; topical
1.2
7.4
2096
18725
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
1.4
7.4
289
2052
H02AB04
ATC
methylprednisolone; systemic
1.2
7.4
1024
8613
BA1AQ
NOMESCO Finland
Thyroid SPECT with low dose CT
80.2
7.4
8
*
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
3.5
7.4
24
68
D37.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Stomach
2.4
7.4
48
201
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.1
7.4
2461
22248
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.2
7.4
1067
9015
C09CA03
ATC
valsartan; oral
1.3
7.4
616
4903
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
1.6
7.4
172
1100
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
2.8
7.4
36
131
R01AD05
ATC
budesonide; nasal
1.3
7.4
498
3858
E0000UV, ,
ATC
1.1
7.3
3066
28135
X59
ICD-10 Finland
Exposure to unspecified factor
1.2
7.3
1196
10218
A97
ICPC
No disease
1.2
7.3
1200
10256
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.2
7.3
1340
11566
R03AK11
ATC
formoterol and fluticasone; inhalant
1.6
7.3
155
969
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
+∞
7.3
7
*
WYA10
NOMESCO Finland
Emergency care or similar visit
1.3
7.3
445
3399
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
1.4
7.3
273
1927
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
1.3
7.3
708
5740
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.2
7.3
1477
12863
R35
ICD-10 Finland
Polyuria
1.4
7.3
370
2750
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.3
7.3
596
4735
WX722
NOMESCO Finland
PEEP
1.5
7.2
234
1606
L03.0
ICD-10 Finland
Cellulitis of finger and toe
1.3
7.2
472
3642
Z02.7
ICD-10 Finland
Issue of medical certificate
1.3
7.2
425
3231
C10AA03
ATC
pravastatin; oral
1.3
7.2
486
3766
N05CF02
ATC
zolpidem; oral
1.2
7.2
1200
10277
C08DB01
ATC
diltiazem; oral
1.4
7.2
354
2619
2509
FHL
Other measure in this category
30.0
7.1
9
*
E03.3
ICD-10 Finland
Postinfectious hypothyroidism
30.0
7.1
9
*
WZC00, ,
SPAT
1.3
7.1
601
4790
PHD99
NOMESCO Finland
Resection of other vein
1.3
7.1
481
3726
M50.3
ICD-10 Finland
Other cervical disc degeneration
1.6
7.1
148
922
M13.9
ICD-10 Finland
Arthritis, unspecified
1.3
7.1
471
3640
SPAT1283
SPAT
Restricted health certificate
1.2
7.1
779
6404
S10
ICPC
Boil/carbuncle
1.4
7.1
332
2437
N06AB04
ATC
citalopram; systemic
1.2
7.1
1469
12817
R39.1
ICD-10 Finland
Other difficulties with micturition
1.6
7.0
144
893
J01DA08
ATC
[U] cefaclor
1.3
7.0
554
4378
ZA8.2
ICD-10 Finland
Fault, injury or illness on the neck or neck
2.3
7.0
52
231
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.2
7.0
1716
15162
D06AX01
ATC
fusidic acid; topical
1.3
7.0
580
4612
SPAT1104
SPAT
Monitoring of emergency patient
1.3
7.0
409
3104
H02
ICPC
Hearing complaint
1.2
7.0
1007
8505
M75.3
ICD-10 Finland
Calcific tendinitis of shoulder
1.7
7.0
126
757
K86
ICPC
Hypertension uncomplicated
1.2
7.0
981
8266
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
1.2
7.0
874
7283
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.2
6.9
1112
9485
L05
ICPC
Flank/axilla symptom/complaint
1.3
6.9
381
2866
R06.4
ICD-10 Finland
Hyperventilation
1.8
6.9
91
499
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
1.3
6.9
497
3882
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
1.4
6.9
362
2703
RD211, ,
NOMESCO Finland
1.4
6.9
269
1913
L99
ICPC
Musculoskeletal disease other
1.6
6.9
142
883
XQ800
NOMESCO Finland
Prick test
1.3
6.9
430
3296
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
1.4
6.9
332
2448
L50.9
ICD-10 Finland
Urticaria, unspecified
1.5
6.9
211
1434
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.3
6.9
676
5488
I49.4
ICD-10 Finland
Other and unspecified premature depolarization
1.5
6.9
237
1648
R07.2
ICD-10 Finland
Precordial pain
1.6
6.9
134
822
G50.1
ICD-10 Finland
Atypical facial pain
1.7
6.8
119
708
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.3
6.8
382
2881
SPAT1240
SPAT
Therapeutic discussion
1.3
6.8
533
4210
C10AX09
ATC
ezetimibe; oral
1.2
6.8
972
8205
M01AB55
ATC
diclofenac, combinations; oral
1.3
6.8
493
3858
R06.2
ICD-10 Finland
Wheezing
1.4
6.8
253
1786
J38.1
ICD-10 Finland
Polyp of vocal cord and larynx
2.2
6.8
54
248
C07AA07
ATC
sotalol; systemic
1.5
6.7
211
1440
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
1.6
6.7
160
1030
SPAT1059
SPAT
Spirometry at the office
1.4
6.7
321
2364
L14
ICPC
Leg/thigh symptom/complaint
1.3
6.7
543
4308
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.1
6.7
2719
24872
LCD10
NOMESCO Finland
Vaginal hysterectomy
1.4
6.7
267
1907
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.2
6.7
901
7561
I86.8
ICD-10 Finland
Varicose veins of other specified sites
3.4
6.7
23
68
R01BA51
ATC
phenylpropanolamine, combinations; oral
1.2
6.7
663
5389
N03AE01
ATC
clonazepam; systemic
1.4
6.7
349
2607
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
1.5
6.7
173
1136
UJD02
NOMESCO Finland
Gastroscopy
1.4
6.6
297
2164
J01MA06
ATC
norfloxacin; oral
1.2
6.6
1031
8770
N05CF01
ATC
zopiclone; oral
1.1
6.6
2448
22256
Z31.5
ICD-10 Finland
Genetic counselling
1.4
6.6
295
2148
K04
ICPC
Palpitations/awareness of heart
1.3
6.6
365
2749
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.2
6.6
1296
11250
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
1.3
6.6
598
4810
J05AB01
ATC
aciclovir; systemic
1.2
6.6
1598
14110
N02BF02
ATC
pregabalin; oral
1.3
6.5
361
2718
LCA06
NOMESCO Finland
Biopsy of endometrium
1.2
6.5
957
8094
K85
ICPC
Elevated blood pressure
1.2
6.5
1272
11035
A10BJ05
ATC
dulaglutide; parenteral
1.8
6.5
97
553
J30.0
ICD-10 Finland
Vasomotor rhinitis
1.5
6.5
163
1062
N30.0
ICD-10 Finland
Acute cystitis
1.2
6.5
1340
11681
Z01.9
ICD-10 Finland
Special examination, unspecified
1.3
6.5
372
2819
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
2.2
6.5
48
214
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
1.3
6.5
344
2577
H81
ICPC
Excessive ear wax
1.2
6.4
1168
10070
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.3
6.4
459
3583
C05AA01
ATC
hydrocortisone; rectal, topical
1.4
6.4
329
2449
ZYC06
NOMESCO Finland
Real-time text-based remote transaction
3.5
6.4
21
60
C08DA01
ATC
verapamil; systemic
1.4
6.4
279
2023
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
1.4
6.4
306
2253
K43
ICPC
Cardiovascular, Other diagnostic procedure
1.9
6.4
77
411
E22.0
ICD-10 Finland
Acromegaly and pituitary gigantism
7.4
6.4
14
19
K78
ICPC
Atrial fibrillation/flutter
1.3
6.4
499
3941
J01FA01
ATC
erythromycin; systemic
1.2
6.4
820
6849
I50.9
ICD-10 Finland
Heart failure, unspecified
1.2
6.4
930
7863
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
1.7
6.4
110
654
SPAT1285
SPAT
Provision of consultation response
1.3
6.4
339
2539
A02BD03
ATC
lansoprazole, amoxicillin and metronidazole; systemic
1.3
6.4
473
3712
NA2AD
NOMESCO Finland
Thoracic spine CT examination
2.3
6.4
43
184
G04CA01
ATC
alfuzosin; oral
1.3
6.4
351
2644
SPAT1377
SPAT
Polysomnography
1.5
6.4
172
1140
C09AA02
ATC
enalapril; systemic
1.2
6.3
1342
11717
DQE20
NOMESCO Finland
Implantation of foreign material in vocal chord
8.1
6.3
13
16
XX9AQ
NOMESCO Finland
Supplementary SPECT-CT or additional scan
3.6
6.3
20
56
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
1.7
6.3
116
702
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.2
6.3
1585
14026
A02BX02
ATC
sucralfate; oral
1.4
6.3
265
1912
N95.0
ICD-10 Finland
Postmenopausal bleeding
1.2
6.3
793
6612
N81.6
ICD-10 Finland
Rectocele
1.3
6.3
592
4784
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.2
6.3
1707
15192
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
1.7
6.3
117
711
SPAT1130
SPAT
Esophagoscopy, gastroscopy and duodenoscopy
1.5
6.3
188
1274
24503
ICD-8 Finland
Thyroiditis, Chronica
+∞
6.2
6
*
E042, D440,
ICD-10 Finland
+∞
6.2
6
*
24191, ,
ICD-8 Finland
+∞
6.2
6
*
BA1AN
NOMESCO Finland
Thyroid gland isotope imaging
+∞
6.2
6
*
2561
FHL
reoperation due to wound complication
+∞
6.2
6
*
R09.1
ICD-10 Finland
Pleurisy
1.7
6.2
98
568
K07
ICPC
Swollen ankles/oedema
1.3
6.2
331
2479
E78.29
ICD-10 Finland
Other mixed hyperlipidaemia
2.1
6.2
53
250
C73.94
ICD-10 Finland
Medullary thyroid carcinoma (thyroid)
26.7
6.2
8
*
E01.1
ICD-10 Finland
Iodine-deficiency-related multinodular (endemic) goitre
26.7
6.2
8
*
8305
FHL
Supravaginal amputation or resection
1.5
6.2
161
1057
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
1.5
6.2
178
1194
ELB40
NOMESCO Finland
Partial parotidectomy
1.9
6.2
71
373
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
1.4
6.2
248
1774
I49.8
ICD-10 Finland
Other specified cardiac arrhythmias
1.5
6.2
190
1293
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
1.3
6.2
515
4102
KH1AD
NOMESCO Finland
CT of urinary organs
1.5
6.2
163
1075
E55.9
ICD-10 Finland
Vitamin D deficiency, unspecified
2.5
6.2
36
144
5742A
ICD-9 Finland
Cholelithiasis, Calculus of gallbladder without mention of cholecystitis[CHOLECYSTOLITHIASIS SINE CHOLECYSTITIDE,SINE OBSTR]
1.5
6.1
157
1028
IHA10
NOMESCO Finland
Structured mapping of problematic alcohol use
2.7
6.1
32
121
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.4
6.1
289
2125
TKC22
NOMESCO Finland
Catheterisation instruction
1.7
6.1
100
586
J38.5
ICD-10 Finland
Laryngeal spasm
3.4
6.1
21
62
H29
ICPC
Ear symptom/complaint other
1.2
6.1
790
6602
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
1.9
6.1
69
361
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
1.5
6.1
171
1142
N41.1
ICD-10 Finland
Chronic prostatitis
2.0
6.1
61
306
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
1.5
6.1
175
1175
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.4
6.1
301
2230
E89.1
ICD-10 Finland
Postprocedural hypoinsulinaemia
12.5
6.1
10
8
D11
ICPC
Diarrhoea
1.2
6.1
683
5628
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
1.6
6.1
141
904
ABC26
NOMESCO Finland
Open discectomy of lumbar spine
1.7
6.1
100
588
U02
ICPC
Urinary frequency/urgency
1.2
6.1
1142
9877
R06AX22
ATC
ebastine; oral
1.2
6.0
1156
10010
H02AB07
ATC
prednisone; oral
1.2
6.0
942
8014
H11.3
ICD-10 Finland
Conjunctival haemorrhage
1.4
6.0
273
1994
K29.0
ICD-10 Finland
Acute haemorrhagic gastritis
2.3
6.0
44
195
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
2.1
6.0
52
247
T99
ICPC
Endocr/metab/nutrit disease other
1.8
6.0
88
500
C10AA01
ATC
simvastatin; oral
1.1
6.0
3224
29945
X15
ICPC
Vaginal symptom/complaint other
1.4
6.0
208
1450

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
916
1693
5.92
307.65
1.4
1.2
—
—
—
0
0
1706
2307
8.92
307.65
3.5
1.6
4.50
4.39
pmol/l
3.39
1529
1992
466
174
28.21
307.65
5.8
1.1
52.03
229.90
u/ml
1.10
163
24
626
713
9.37
307.65
1.5
1.1
22.16
2.05
iu/l
0.56
173
146
7854
55867
4.59
307.65
7.7
2.6
15.62
14.56
pmol/l
230.50
7374
49714
393
44
93.42
307.65
6.6
1.3
—
—
—
0
0
1046
3227
3.54
279.28
1.2
1.1
105.65
72.84
iu/ml
2.23
378
1023
1493
5863
2.86
263.82
3.3
3.3
66.20
90.07
ng/l
21.59
1285
4949
5649
39426
2.20
262.56
7.2
6.0
1.21
1.22
mmol/l
13.71
4858
33223
8160
68339
3.47
233.97
9.1
3.6
1.83
2.05
mu/l
0.59
7676
61586
5063
35757
1.97
203.98
6.2
5.3
1.21
1.22
mmol/l
15.85
4694
32248
3564
23813
1.83
155.69
4.8
3.7
7.40
7.40
ph
1.03
668
4337
3792
27440
1.67
113.73
3.2
3.4
2.34
2.37
mmol/l
24.92
3325
23642
6647
56283
1.73
102.49
4.6
4.2
12.76
13.59
mm/h
4.95
6157
51734
4319
33243
1.58
94.41
2.5
2.2
79.22
79.93
nmol/l
0.95
3897
29387
6731
58712
1.61
76.01
7.5
7.4
77.34
79.10
u/l
2.99
6384
54883
5248
43645
1.50
70.86
4.3
4.3
6.66
6.67
mmol/l
0.13
4972
40837
4376
35237
1.48
68.37
2.5
2.5
—
—
—
0
0
355
1326
2.75
66.03
2.6
2.7
—
—
—
0
0
7995
73884
1.85
62.42
16.2
14.6
20.90
23.59
mg/l
11.30
6566
58361
533
2468
2.23
62.24
2.2
1.3
—
—
—
0
0
353
1380
2.62
59.98
2.0
1.7
5.31
4.97
mmol/24h
0.89
305
1192
90
134
6.78
57.50
1.5
1.3
14.95
14.85
pmol/l
0.07
74
109
8227
77055
1.95
56.81
19.0
16.6
139.92
139.67
mmol/l
16.62
8063
74999
3138
24303
1.45
56.39
2.1
2.3
—
—
—
0
0
3984
32275
1.43
55.81
2.3
2.1
—
—
—
0
0
8237
77241
1.95
55.74
19.1
16.8
3.93
3.95
mmol/l
8.98
8062
75025
5064
43002
1.41
53.24
8.3
9.2
4.01
4.09
e9/l
1.53
4392
37284
4523
37822
1.40
50.99
5.8
5.9
0.19
0.19
e9/l
0.46
3932
32841
4139
34241
1.39
48.91
6.3
6.3
—
—
—
0
0
4466
37474
1.39
48.14
5.7
5.8
1.93
1.90
e9/l
0.39
3919
32779
4359
36546
1.38
46.59
5.7
5.7
0.57
0.58
e9/l
1.76
3748
31236
5978
52829
1.40
46.20
4.4
3.8
—
—
—
0
0
993
6211
1.67
46.14
2.2
2.0
368.39
382.33
nmol/l
1.47
912
5647
3740
30615
1.38
46.13
3.0
2.7
104.35
124.08
ug/l
7.26
3433
28048
4364
36653
1.38
45.82
5.7
5.8
0.04
0.04
e9/l
0.29
3752
31311
8104
76265
1.74
44.99
16.3
13.6
—
—
—
0
0
7774
72419
1.60
44.54
5.3
4.6
5.96
5.91
mmol/l
3.65
7104
65212
7411
68342
1.52
44.06
6.6
5.7
40.10
39.64
mmol/mol
4.10
6857
62422
3530
28790
1.38
43.78
4.0
3.6
33.30
70.55
ng/l
1.31
2448
20067
4670
39948
1.36
42.11
5.4
6.0
10.71
10.96
umol/l
0.80
4440
37763
4418
37487
1.36
41.90
6.2
5.3
0.00
0.00
estimate
0.15
812
6590
4049
33917
1.36
41.66
4.3
4.5
35.77
35.24
g/l
8.33
3742
31243
5920
52605
1.38
41.59
5.1
4.7
—
—
—
0
0
2848
22613
1.38
40.90
3.0
2.9
1234.42
1436.33
ng/l
1.83
2452
19411
1003
6478
1.62
40.77
4.6
3.5
1.22
1.24
mmol/l
7.64
897
5607
2959
23667
1.38
40.53
2.5
2.4
60.34
63.58
u/l
0.37
2747
21598
1321
9110
1.53
40.31
5.1
4.9
1.05
1.04
mmol/l
1.39
1203
8396
4440
37921
1.34
39.23
4.6
4.0
0.00
0.00
estimate
1.60
795
6599
4379
37369
1.34
38.68
4.7
4.0
0.00
0.00
estimate
0.23
882
7139
4183
35464
1.34
38.58
17.1
14.9
1.27
1.27
inr
0.06
1141
9934
2154
16478
1.41
38.06
1.7
1.7
1.05
1.25
mg/l
3.45
1664
12696
4144
35195
1.33
37.25
6.0
6.1
28.11
27.61
%
2.11
3877
32740
5786
51619
1.35
37.02
5.5
4.8
1722.86
2313.32
e6/l
0.43
96
677
7880
74251
1.56
36.00
5.6
5.0
2.75
2.78
mmol/l
2.70
7270
67418
3924
33198
1.33
35.64
5.9
6.0
0.69
0.68
%
0.45
3638
30685
4053
34462
1.32
35.47
6.1
6.3
8.45
8.50
%
0.41
3778
32008
4032
34278
1.32
35.24
5.9
6.0
2.83
2.79
%
0.56
3759
31757
8234
78492
1.70
34.90
11.7
10.6
23.61
24.05
u/l
1.70
7957
75278
4071
34704
1.32
34.69
5.8
5.9
57.27
57.61
%
1.05
3805
32257
3582
30037
1.32
34.11
4.3
3.7
5.92
5.89
ph
0.20
208
1775
1627
12045
1.43
34.08
2.7
3.0
0.82
0.81
mmol/l
1.76
1499
11167
3814
32476
1.31
31.71
2.1
2.0
97.36
96.75
pmol/l
0.31
1897
15504
7697
72533
1.47
31.31
5.0
4.4
4.70
4.78
mmol/l
9.21
7100
66169
7639
71907
1.45
31.01
4.9
4.4
1.51
1.57
mmol/l
24.65
6994
65207
6848
63319
1.36
30.57
19.4
17.3
15.19
15.11
%
0.50
6760
62120
3787
32382
1.30
29.86
10.1
9.6
0.00
0.00
e9/l
1.83
3113
26260
1660
12589
1.39
29.80
1.3
1.3
11.33
13.38
u/ml
0.55
640
4631
2747
22565
1.32
28.98
4.3
3.9
—
—
—
0
0
2017
15860
1.35
28.72
1.3
1.2
1.13
1.51
u/ml
1.39
547
4035
1724
13231
1.38
28.64
1.3
1.3
37.19
36.03
iu/ml
0.07
520
4379
7368
69201
1.39
27.67
4.4
3.9
1.30
1.25
mmol/l
7.06
6679
62095
8418
81241
1.73
27.34
25.2
21.5
39.74
39.40
%
2.61
7857
75245
8421
81304
1.73
26.95
25.3
21.5
257.44
256.64
e9/l
0.53
8231
78865
8424
81341
1.73
26.95
25.3
21.4
6.66
6.65
e9/l
0.06
8218
78596
8423
81338
1.73
26.81
25.2
21.4
90.80
91.32
fl
23.94
8336
79941
1977
15635
1.34
26.80
2.9
3.0
2.44
2.47
mmol/l
11.97
1752
13638
8423
81344
1.73
26.72
25.3
21.4
4.45
4.39
e12/l
32.90
8220
78607
8422
81332
1.73
26.72
25.2
21.3
30.07
30.26
pg
21.53
8335
79928
2448
19973
1.31
26.63
5.1
4.5
0.00
0.00
estimate
0.14
793
6483
8423
81358
1.72
26.51
25.5
21.6
133.07
132.01
g/l
11.58
8334
79976
2275
18440
1.31
25.80
2.1
2.3
—
—
—
0
0
95
288
3.32
25.66
2.0
1.6
17.55
17.39
nmol/l
0.06
88
271
2267
18453
1.31
24.73
2.7
2.5
6079.89
5114.06
umol/l
0.43
1956
15822
1361
10287
1.38
24.42
1.3
1.3
—
—
—
0
0
2292
18757
1.30
23.86
2.3
2.3
3.14
3.05
mg/l
0.84
1960
15916
2758
23130
1.28
23.67
2.1
2.1
152.93
191.00
u/l
2.28
2571
21510
31
38
8.18
23.48
2.8
1.2
14.72
23.26
pmol/l
—
10
10
1872
14942
1.32
23.32
3.2
2.9
491.67
513.62
mosm/kgh2o
0.44
1602
12676
3139
26807
1.26
23.04
4.2
3.6
86.85
119.13
e6/l
1.98
2234
18370
2326
19146
1.29
23.00
3.4
3.7
91.98
91.52
%
0.38
2267
18667
2707
22741
1.27
22.69
3.8
3.6
7.60
8.18
mg/mmol
0.28
1613
13264
1393
10732
1.35
21.94
1.3
1.2
—
—
—
0
0
2024
16445
1.30
21.93
1.7
1.7
20767795.93
33615976.44
pmol/l
0.70
1642
13348
2657
22377
1.27
21.56
3.1
3.0
6.62
6.59
mmol/l
0.16
2233
18591
2569
21595
1.27
21.07
3.2
3.1
619.98
440.55
mg/l
0.79
1541
12656
3219
27785
1.25
20.97
3.6
3.3
—
—
—
0
0
2009
16399
1.29
20.84
5.1
4.5
1.02
1.02
kg/l
0.04
283
2579
5020
45505
1.24
20.71
3.0
3.0
45.63
47.51
u/l
0.68
4631
41784
772
5479
1.45
19.62
1.5
1.4
—
—
—
0
0
1268
9833
1.34
18.88
1.4
1.3
465.05
555.61
titre
1.34
289
2206
1268
9840
1.34
18.79
8.2
7.1
—
—
—
0
0
1065
8050
1.37
18.75
5.0
4.0
—
—
—
0
0
2648
22613
1.24
18.36
3.5
3.2
71.60
77.27
e6/l
0.07
2037
16939
2287
19258
1.25
17.88
4.3
3.7
—
—
—
0
0
2454
20946
1.24
16.76
3.3
3.1
0.34
0.46
e6/l
1.51
1880
15689
1893
15719
1.26
16.49
2.7
2.6
5.61
6.84
e6/l
4.87
1687
13983
594
4176
1.45
15.82
1.3
1.3
116.38
203.95
u/ml
4.20
542
3802
180
940
1.93
15.33
1.4
1.3
46.41
52.51
mu/l
0.24
163
836
127
587
2.18
15.07
1.3
1.2
—
—
—
0
0
2169
18451
1.23
14.97
4.5
3.9
—
—
—
0
0
2372
20391
1.22
14.75
3.3
3.0
—
—
—
0
0
514
3572
1.47
14.54
3.4
3.1
25.76
25.37
mmol/l
2.06
493
3476
730
5410
1.38
14.40
1.3
1.2
—
—
—
0
0
443
2997
1.50
14.33
1.3
1.2
0.46
1.34
u/ml
2.09
39
291
1638
13584
1.25
14.16
1.4
1.5
2.33
2.43
g/l
0.62
946
7705
2340
20157
1.22
14.15
1.7
1.6
1.38
1.32
mmol/l
2.90
1991
16790
609
4406
1.41
13.85
3.1
3.0
129.13
126.16
g/l
3.00
591
4303
1070
8443
1.30
13.81
1.3
1.3
—
—
—
0
0
2165
18560
1.22
13.65
1.6
1.5
21.12
21.08
nmol/l
0.03
1869
15473
1073
8547
1.29
12.85
1.9
1.7
—
—
—
0
0
166
903
1.85
12.57
1.2
1.3
282.65
289.31
pmol/l
0.14
150
780
827
6380
1.33
12.52
2.3
2.6
65.96
66.25
g/l
0.49
735
5711
1566
13082
1.24
12.51
2.9
2.7
1.21
1.57
e6/l
0.85
894
7263
135
695
1.96
12.09
1.8
1.3
—
—
—
0
0
1251
10229
1.26
12.06
2.0
2.0
—
—
—
0
0
172
959
1.81
12.05
1.3
1.3
—
—
nmol/l
—
0
0
880
6888
1.31
12.00
3.5
3.5
7.38
7.39
ph
—
10
43
42
125
3.37
11.87
2.5
1.7
1.32
1.10
ug/l
0.25
37
119
190
1099
1.74
11.76
1.3
1.3
0.32
0.25
nmol/l
0.15
12
84
1082
8727
1.27
11.68
1.9
2.1
124.49
129.38
ug/g
0.16
843
6754
847
6634
1.31
11.48
3.5
3.5
5.89
5.82
kpa
1.22
816
6440
189
1100
1.73
11.46
1.3
1.3
0.63
1.71
nmol/l
0.52
181
1049
501
3627
1.40
11.37
3.2
2.6
0.18
0.30
e6/l
3.88
488
3515
70
284
2.48
11.32
1.6
1.6
5.03
4.64
nmol/l
0.06
55
237
1128
9181
1.26
11.27
5.5
6.2
104.25
104.14
mmol/l
0.32
1128
9173
222
1356
1.65
11.25
1.8
1.5
289.55
291.55
mu/l
0.03
198
1228
1758
15030
1.21
11.06
1.7
1.7
1203.89
1185.54
nmol/l
0.32
1339
11121
2605
23101
1.18
10.88
3.1
3.1
31.41
35.07
u/l
1.47
2464
21821
1427
11966
1.23
10.87
3.2
2.8
3.99
3.85
e6/l
0.13
771
6198
867
6870
1.29
10.75
6.0
6.9
120.41
118.95
g/l
1.43
851
6669
310
2074
1.51
10.66
5.1
4.8
—
—
—
0
0
839
6641
1.29
10.49
3.5
3.5
2.27
2.07
mmol/l
0.91
734
5692
780
6145
1.30
10.10
4.1
4.0
0.98
0.92
%
0.24
261
2085
1748
15084
1.20
9.83
3.9
3.7
207.83
358.63
ng/l
0.78
1346
11927
705
5510
1.30
9.70
4.2
4.0
0.68
0.43
%
0.20
185
1500
742
5841
1.30
9.67
4.2
4.0
0.12
0.11
%
0.07
222
1791
1351
11418
1.22
9.42
2.6
2.3
12.79
12.42
umol/l
0.84
1257
10543
1023
8415
1.24
9.24
5.6
6.3
1.51
1.25
mmol/l
1.41
843
6774
169
1015
1.68
9.22
1.3
1.3
—
—
—
0
0
1252
10523
1.22
9.22
2.6
2.3
2.38
2.34
g/l
1.24
1166
9666
798
6381
1.28
9.19
2.2
2.3
5.30
5.97
ug/l
0.56
687
5385
912
7416
1.26
9.12
5.7
6.6
95.78
95.80
%
0.04
888
7126
1034
8556
1.24
8.83
2.2
2.6
7.58
8.26
umol/l
0.40
871
7347
794
6376
1.27
8.83
3.9
3.6
—
—
—
0
0
597
4622
1.31
8.81
6.7
6.5
24.94
24.79
mmol/l
0.45
577
4387
159
955
1.68
8.70
1.3
1.2
15.35
15.38
u/l
0.01
124
776
1016
8417
1.23
8.58
5.7
6.3
5.15
5.10
kpa
0.81
979
8009
1014
8415
1.23
8.42
5.7
6.3
12.56
12.46
kpa
0.21
976
8011
796
6448
1.26
8.22
1.4
1.5
—
—
—
0
0
339
2432
1.41
8.19
2.6
2.6
—
—
—
0
0
578
4503
1.30
8.16
1.3
1.3
61.31
55.96
au/ml
0.20
24
245
269
1853
1.47
8.10
1.1
1.1
—
—
—
0
0
1170
9897
1.21
8.02
2.7
2.4
21.22
21.50
%
0.27
986
8365
669
5332
1.28
7.92
2.3
2.4
—
—
—
0
0
75
368
2.05
7.84
1.8
1.7
173.39
178.66
pmol/l
0.15
70
340
694
5565
1.27
7.82
4.0
3.9
0.75
0.67
%
0.21
210
1780
325
2339
1.40
7.73
1.6
1.6
273.67
308.22
titre
0.07
15
107
2247
20133
1.16
7.71
4.1
4.2
—
—
—
0
0
525
4073
1.31
7.66
1.3
1.3
—
—
—
0
0
71
347
2.05
7.52
1.4
1.6
6.90
9.02
ug/l
1.01
66
305
2536
22953
1.15
7.51
3.3
2.9
—
—
—
0
0
614
4890
1.27
7.32
4.2
4.5
—
—
—
0
0
2154
19307
1.15
7.29
5.9
7.0
—
—
—
0
0
301
2168
1.40
7.16
1.5
1.6
1.20
1.19
g/l
0.29
281
2047
622
4976
1.27
7.16
2.3
2.4
29.13
26.35
au/ml
0.23
38
360
293
2101
1.41
7.15
1.6
1.6
0.24
0.23
g/l
0.21
273
1978
1015
8571
1.21
7.06
1.4
1.4
—
—
—
0
0
897
7487
1.22
7.03
1.6
1.6
—
—
—
0
0
890
7423
1.22
7.02
1.4
1.4
—
—
—
0
0
401
3038
1.34
6.95
1.1
1.1
1.07
1.92
u/ml
—
9
40
631
5081
1.26
6.88
2.8
3.0
5.42
4.90
e9/l
0.37
506
3911
704
5748
1.24
6.80
2.8
3.9
52.60
65.07
u/ml
0.28
676
5535
406
3094
1.33
6.77
4.3
4.7
1.60
1.59
%
0.09
389
2898
679
5527
1.25
6.74
3.2
2.9
4.44
4.52
kpa
0.53
655
5351
379
2862
1.34
6.73
1.3
1.3
33.45
35.53
iu/l
0.48
328
2501
403
3072
1.33
6.71
4.3
4.8
0.91
0.90
%
0.31
387
2878
304
2219
1.38
6.70
1.1
1.1
—
—
—
0
0
487
3815
1.29
6.64
6.8
8.2
—
—
—
0
0
368
2775
1.34
6.60
1.6
1.6
—
—
—
0
0
399
3045
1.32
6.59
1.5
1.5
11.26
20.03
u/ml
1.09
13
73
222
1539
1.45
6.55
2.1
2.2
128.24
70.82
ug/min
0.72
120
845
289
2103
1.39
6.51
1.3
1.3
10.24
38.13
u/ml
3.21
15
144
224
1559
1.45
6.48
1.2
1.2
34.96
47.20
u/ml
0.62
22
192
150
961
1.57
6.45
1.6
1.6
58.56
57.96
%
0.06
87
587
842
7065
1.21
6.26
2.2
2.4
36.32
41.10
u/l
0.43
705
5999
20
57
3.51
6.15
1.7
1.4
—
—
—
0
0
257
1853
1.40
6.13
1.9
1.9
11.48
11.67
mg/l
0.16
233
1695
139
891
1.57
5.99
1.3
1.3
29.63
34.56
u/l
0.86
102
735
240
1722
1.40
5.91
2.3
2.0
10.73
11.01
nmol/l
0.20
208
1484
541
4365
1.25
5.83
2.5
2.4
—
—
—
0
0
304
2274
1.35
5.80
1.5
1.4
300.51
277.67
ug/g
1.25
188
1325
961
8223
1.19
5.78
2.3
2.4
1.77
1.83
%
1.19
849
7201
515
4176
1.25
5.34
3.4
3.4
7.42
7.42
ph
0.28
74
554
379
2963
1.29
5.32
5.0
4.3
—
—
—
0
0
63
337
1.88
5.28
2.7
2.2
1935.18
1826.58
ml
0.40
57
297
591
4872
1.23
5.26
1.4
1.3
—
—
—
0
0
520
4231
1.24
5.23
3.4
3.4
5.29
5.17
kpa
2.31
485
3982
1283
11339
1.15
5.13
2.0
2.0
29.48
29.59
s
0.22
1240
10984
259
1936
1.35
5.02
1.3
1.4
7.00
14.50
iu/ml
—
8
42
39
179
2.18
4.98
1.2
1.5
—
—
—
0
0
1030
8983
1.17
4.92
6.0
5.3
3.41
3.94
ug/l
0.22
918
7903
228
1679
1.37
4.88
2.2
2.2
128.19
125.45
g/l
0.91
169
1187
198
1425
1.40
4.87
2.3
1.9
5120.08
4008.58
u/l
0.20
70
554
690
5830
1.20
4.80
1.2
1.2
—
—
—
0
0
309
2386
1.31
4.80
3.0
3.1
—
—
—
0
0
381
3040
1.26
4.59
1.9
2.3
7.44
7.56
g/l
0.68
328
2701
108
700
1.55
4.54
1.5
1.5
31.54
31.89
%
0.03
61
414
254
1927
1.33
4.50
1.3
1.3
4.12
5.86
u/ml
0.81
47
337
722
6163
1.19
4.49
4.7
4.3
—
—
—
0
0
379
3032
1.26
4.47
1.9
2.3
3.71
3.66
g/l
0.11
327
2695
78
470
1.67
4.43
1.7
1.7
—
—
—
0
0
364
2915
1.26
4.28
1.9
1.9
2.26
2.47
ug/l
0.10
324
2554
176
1278
1.38
4.16
1.5
1.5
—
—
—
0
0
139
972
1.44
4.08
2.8
2.3
—
—
—
0
0
321
2560
1.26
3.94
2.3
3.0
0.28
0.27
g/l
0.06
114
903
94
613
1.54
3.91
1.9
1.9
3.88
3.86
mg/l
0.01
94
580
352
2841
1.25
3.90
1.9
2.4
2.98
2.99
g/l
0.07
300
2502
693
5971
1.17
3.89
6.3
7.0
—
—
—
0
0
793
6907
1.16
3.88
2.6
2.8
176.49
194.79
ng/l
0.78
727
6322
258
2007
1.29
3.87
1.4
1.4
—
—
—
0
0
246
1902
1.30
3.86
1.3
1.3
7.41
5.51
u/ml
0.12
28
216
139
985
1.42
3.82
2.8
2.3
3.99
4.04
mmol/l
0.81
139
977
139
985
1.42
3.82
2.8
2.3
105.83
105.47
mmol/l
0.40
139
977
365
2968
1.24
3.79
3.5
3.5
—
—
—
0
0
78
494
1.58
3.70
1.4
1.3
1.06
1.31
u/ml
0.11
45
287
61
363
1.69
3.70
1.5
1.5
1.15
4.22
%
2.68
13
68
313
2511
1.26
3.67
3.2
3.3
69.49
53.14
mg/l
0.43
261
2003
350
2845
1.24
3.66
1.9
2.3
9.57
10.17
g/l
2.09
298
2485
215
1649
1.31
3.61
1.5
1.7
—
—
—
0
0
37
191
1.94
3.56
11.2
11.7
0.70
0.60
mmol/l
1.83
31
173
6275
61094
1.09
3.53
22.2
19.2
330.64
330.67
g/l
0.11
6241
60621
320
2587
1.25
3.53
3.6
3.7
25.30
25.07
mmol/l
0.69
291
2351
50
286
1.75
3.50
1.1
1.2
155.08
139.58
mmol/24h
0.71
50
286
143
1036
1.39
3.50
1.1
1.1
9.07
16.29
au/ml
—
6
41
155
1140
1.37
3.46
1.2
1.2
—
—
—
0
0
485
4103
1.19
3.41
4.6
3.8
—
—
—
0
0
425
3552
1.21
3.41
1.2
1.2
—
—
—
0
0
310
2509
1.24
3.40
3.2
3.3
31.90
45.27
mg/l
2.40
257
2005
728
6370
1.16
3.37
5.1
5.9
1.28
1.35
mmol/l
1.19
711
6198
302
2443
1.24
3.33
3.0
3.3
6.76
4.46
ratio
0.17
28
173
291
2345
1.25
3.32
4.6
5.5
1.29
1.30
mmol/l
0.06
265
2071
975
8715
1.13
3.31
1.7
1.6
—
—
—
0
0
1014
9124
1.13
3.10
3.6
3.9
7.88
24.43
ug/l
3.19
823
7387
136
1001
1.36
3.07
1.1
1.1
0.90
1.69
u/ml
0.92
69
471
238
1895
1.26
3.04
1.1
1.1
7.67
9.41
u/ml
0.14
30
174
258
2076
1.25
3.02
1.1
1.1
—
—
—
0
0
292
2382
1.23
3.02
1.7
2.2
37.72
37.48
g/l
0.28
239
2034
108
769
1.41
2.98
1.9
2.1
—
—
—
0
0
5
5
10.00
2.98
6.8
1.0
2.02
2.90
mu/l
—
5
5
93
647
1.44
2.92
1.2
1.1
—
—
—
0
0
207
1634
1.27
2.87
4.0
3.6
22.38
26.63
mg/l
1.15
134
1020
159
1213
1.32
2.85
1.4
1.6
—
—
—
0
0
71
471
1.51
2.83
1.7
2.2
7.11
6.95
mmol/l
0.20
56
324
1056
9578
1.12
2.82
5.0
4.6
32.83
33.54
%
1.31
703
6132
147
1116
1.32
2.74
1.3
1.4
—
—
—
0
0
35
195
1.80
2.74
1.2
1.1
494.65
338.08
pmol/l
0.44
20
138
116
852
1.37
2.70
1.1
1.1
1.71
3.41
u/ml
1.48
44
336
184
1444
1.28
2.69
1.7
1.5
—
—
—
0
0
39
226
1.73
2.69
1.2
1.4
2.47
2.65
%
0.05
34
187
227
1828
1.25
2.68
3.5
3.3
0.81
0.81
nmol/l
0.06
189
1427
232
1874
1.24
2.67
4.2
3.7
7.42
7.42
ph
0.35
221
1722
31
168
1.85
2.66
1.2
1.2
96.46
74.12
mu/l
0.19
22
120
109
796
1.37
2.64
1.2
1.4
0.29
0.38
nmol/l
1.16
71
576
290
2405
1.21
2.60
1.7
1.7
—
—
—
0
0
207
1661
1.25
2.54
5.1
6.3
10.82
11.07
mmol/l
0.68
191
1484
207
1662
1.25
2.53
5.1
6.3
105.00
104.91
mmol/l
0.09
191
1485
194
1546
1.26
2.53
4.1
3.4
—
—
—
0
0
301
2515
1.20
2.51
1.4
1.3
—
—
—
0
0
203
1630
1.25
2.49
4.4
3.8
8.70
8.50
kpa
0.55
196
1599
579
5108
1.14
2.46
3.4
3.2
0.78
0.78
ug/l
0.05
436
3614
201
1615
1.25
2.45
4.4
3.8
2.93
2.72
mmol/l
0.48
141
1149
693
6187
1.13
2.45
2.4
2.5
69.93
69.69
e9/l
0.06
518
4627
144
1111
1.30
2.44
2.9
2.5
—
—
—
0
0
201
1617
1.25
2.43
4.4
3.8
5.04
5.04
kpa
0.04
194
1587
230
1878
1.23
2.43
3.6
3.4
—
—
—
0
0
236
1936
1.22
2.39
1.6
1.6
10923.21
13866.20
e6/l
0.61
170
1394
159
1249
1.28
2.36
3.0
2.8
—
—
—
0
0
101
744
1.36
2.35
2.6
2.4
0.60
1.10
g/24h
2.53
53
336
108
805
1.35
2.34
2.7
2.5
—
—
—
0
0
125
953
1.32
2.32
1.4
1.5
33.36
32.14
g/l
0.51
116
862
411
3559
1.16
2.29
1.9
1.9
—
—
—
0
0
201
1630
1.24
2.28
1.3
1.3
217.23
223.23
miu/ml
0.08
77
747
481
4216
1.15
2.27
4.9
6.1
25.51
25.00
mmol/l
2.16
474
4184
661
5916
1.13
2.26
7.3
6.3
10.34
9.87
mmol/l
0.87
629
5611
102
759
1.35
2.25
1.4
1.3
—
—
—
0
0
211
1724
1.23
2.24
2.9
2.9
25.53
25.05
mmol/l
0.98
205
1686
198
1609
1.24
2.22
1.3
1.2
7.78
4.21
u/ml
0.31
25
117
28
157
1.79
2.20
1.4
1.4
74.86
104.80
ng/l
1.47
28
157
122
936
1.31
2.19
1.2
1.2
—
—
—
0
0
726
6550
1.12
2.18
1.6
1.5
—
—
—
0
0
82
597
1.38
2.09
1.2
1.2
—
—
—
0
0
65
455
1.43
2.07
1.1
1.1
4.45
10.30
iu/ml
2.02
11
100
132
1033
1.28
2.06
1.3
1.2
28.25
41.54
u/l
1.04
112
877
151
1202
1.26
2.05
1.7
1.7
0.84
0.79
nmol/l
0.56
131
1003
117
902
1.30
2.05
1.1
1.1
3.34
3.90
u/ml
0.16
62
411
55
374
1.47
2.04
1.2
1.3
—
—
—
0
0
1968
18628
1.07
2.03
1.4
1.4
—
—
—
0
0
125
974
1.29
2.02
1.2
1.2
22.84
55.18
u/ml
1.80
12
85
118
913
1.30
2.02
1.4
1.3
—
—
—
0
0
11
44
2.50
2.01
1.2
1.1
—
—
—
0
0
42
273
1.54
1.94
3.0
2.5
—
—
—
0
0
96
727
1.32
1.93
1.3
1.4
154745.19
121409.19
e6/l
0.15
59
491
54
372
1.45
1.90
1.4
1.4
—
—
—
0
0
41
267
1.54
1.88
1.2
1.4
63.98
64.58
%
0.04
34
216
15
72
2.09
1.86
1.0
1.1
—
—
—
0
0
71
517
1.38
1.85
2.0
2.2
712.24
646.37
ml
0.67
45
350
58
408
1.42
1.84
1.7
1.7
—
—
—
0
0
126
997
1.27
1.84
3.1
2.7
—
—
—
0
0
38
246
1.55
1.80
1.1
1.1
1500.35
1479.88
miu/ml
0.04
38
246
32
200
1.60
1.76
1.0
1.1
1.23
0.64
umol/24h
0.43
13
91
268
2302
1.17
1.73
1.2
1.2
—
—
—
0
0
342
2995
1.15
1.71
2.8
3.3
342.41
2737.91
u/ml
1.68
284
2510
424
3767
1.13
1.71
6.8
7.8
25.00
24.46
mmol/l
2.83
412
3645
21
118
1.78
1.69
1.1
1.4
7.18
13.21
%
0.98
11
61
184
1534
1.20
1.68
2.9
2.4
16.01
15.78
%
0.33
101
761
58
416
1.40
1.68
1.2
1.6
7.94
5.43
u/l
0.40
45
346
186
1553
1.20
1.68
1.1
1.2
—
—
—
0
0
69
511
1.35
1.65
1.2
1.1
—
—
—
0
0
30
188
1.60
1.65
2.6
1.8
—
—
—
0
0
10
42
2.38
1.61
1.2
1.1
—
—
—
0
0
52
369
1.41
1.61
1.0
1.0
—
—
—
0
0
100
785
1.28
1.60
1.2
1.2
—
—
—
0
0
19
106
1.79
1.58
1.3
1.2
—
—
—
0
0
55
396
1.39
1.57
1.0
1.1
2.22
9.19
nmol/l
0.92
15
82
8
172
0.46
1.57
3.3
2.4
145.13
162.24
nmol/l
—
8
141
577
5249
1.11
1.56
2.8
2.9
10.06
10.38
g/l
1.05
530
4823
56
406
1.38
1.54
1.3
1.3
—
—
—
0
0
109
871
1.25
1.52
1.1
1.1
0.86
0.96
u/ml
0.10
48
327
87
676
1.29
1.52
2.3
2.2
2.56
2.78
u/field
0.13
34
255
88
685
1.29
1.52
1.5
1.3
0.42
0.42
g/l
0.04
64
475
88
685
1.29
1.52
1.5
1.3
6.69
6.80
g/l
0.07
64
474
88
686
1.29
1.50
1.5
1.4
—
—
—
0
0
88
686
1.29
1.50
1.5
1.3
2.73
2.78
g/l
0.10
65
479
26
163
1.60
1.45
1.2
1.3
159.14
109.54
nmol/l
0.46
14
111
106
850
1.25
1.45
1.3
1.2
6.97
7.45
mmol/l
1.34
95
732
11
52
2.12
1.44
1.2
1.6
28.17
42.41
%
—
6
37
375
3349
1.13
1.44
1.6
1.6
1.64
1.60
g/l
0.41
320
2859
145
1204
1.21
1.43
3.0
3.3
2.00
1.45
%
0.65
130
1052
116
942
1.23
1.42
6.2
6.0
11.71
12.37
mg/l
0.92
98
856
173
1464
1.19
1.40
1.3
1.4
36.37
34.85
e6/l
0.02
133
1131
173
1465
1.18
1.39
1.3
1.5
792.11
1191.18
e6/l
0.39
141
1190
9
179
0.50
1.39
1.1
1.4
16.08
14.01
g/l
—
9
142
36
247
1.46
1.37
3.8
2.8
27.38
28.08
umol/l
0.17
30
179
129
1067
1.21
1.34
1.6
1.5
0.69
0.70
g/l
0.03
98
791
272
2393
1.14
1.34
1.5
1.4
135.63
174.46
pmol/l
0.90
266
2327
455
4130
1.11
1.32
2.0
2.0
1.40
1.43
g/l
0.08
413
3747
778
7240
1.08
1.31
2.0
2.1
0.22
0.21
g/l
2.49
728
6752
393
3543
1.11
1.30
1.4
1.5
—
—
—
0
0
6
24
2.50
1.30
1.0
1.1
—
—
—
0
0
6
24
2.50
1.30
1.0
1.0
—
—
—
0
0
104
847
1.23
1.27
1.4
1.4
2506.00
2884.24
e6/l
0.13
80
615
840
7852
1.08
1.27
1.6
1.5
—
—
—
0
0
194
1677
1.16
1.24
1.3
1.3
480.88
523.07
mg/l
0.75
186
1580
150
1273
1.18
1.21
1.4
1.4
—
—
—
0
0
14
78
1.80
1.20
1.6
1.3
—
—
—
0
0
31
213
1.46
1.20
1.3
1.4
31.80
34.73
%
0.19
20
140
83
666
1.25
1.18
1.1
1.1
—
—
—
0
0
95
775
1.23
1.17
1.0
1.1
0.66
1.27
u/ml
0.94
49
355
159
1364
1.17
1.14
1.2
1.4
—
—
—
0
0
69
545
1.27
1.13
1.1
1.2
227.00
172.87
titre
—
10
94
75
599
1.25
1.12
1.1
1.2
—
—
—
0
0
7
30
2.33
1.12
4.4
2.8
—
—
—
0
0
220
1938
1.14
1.11
1.2
1.2
555.45
834.67
titre
0.79
11
75
22
144
1.53
1.08
1.1
1.4
15.65
17.51
umol/l
1.54
17
133
61
479
1.28
1.06
1.2
1.7
2.28
4.87
ug/l
1.34
41
360
14
82
1.71
1.05
17.8
11.1
4.76
4.92
mmol/l
0.12
14
82
168
1460
1.15
1.05
1.2
1.3
3.81
3.72
mmol/l
0.56
158
1364
13
76
1.71
0.98
1.2
1.1
—
—
—
0
0
9
49
1.84
0.98
1.7
1.4
—
—
—
0
0
66
531
1.24
0.96
1.3
1.3
1.31
1.42
nmol/l
0.36
57
488
216
1923
1.13
0.96
1.2
1.2
75.00
139.69
titre
1.05
12
162
0
32
0.00
0.95
0.0
1.0
—
5.02
—
0
19
11
62
1.78
0.94
1.7
1.6
—
—
—
0
0
48
376
1.28
0.89
2.0
2.1
488.24
504.08
min
0.67
37
286
48
376
1.28
0.89
1.1
1.3
—
—
—
0
0
19
127
1.50
0.88
1.2
1.1
—
1680.00
—
0
7
194
1729
1.12
0.87
1.1
1.2
—
—
—
0
0
76
632
1.20
0.84
1.2
1.2
351.20
351.10
nmol/l
0.00
64
529
65
532
1.22
0.84
1.5
1.8
7.13
8.47
umol/l
0.25
43
378
6
31
1.94
0.84
1.0
1.1
—
—
—
0
0
101
863
1.17
0.83
1.1
1.1
1.45
1.53
g/l
1.53
95
779
8
46
1.74
0.82
1.0
1.0
—
—
—
0
0
32
241
1.33
0.80
1.0
1.2
—
—
—
0
0
73
610
1.20
0.78
1.1
1.1
—
—
—
0
0
107
925
1.16
0.78
1.4
1.7
—
—
—
0
0
100
860
1.16
0.78
2.5
3.2
—
—
—
0
0
76
640
1.19
0.76
1.1
1.1
1.26
3.12
u/ml
1.89
26
235
0
28
0.00
0.76
0.0
1.0
—
—
—
0
0
189
1702
1.11
0.74
3.5
3.2
222.56
508.43
u/ml
0.85
172
1542
30
227
1.32
0.74
1.7
1.5
7.82
8.45
mmol/l
0.93
30
214
17
116
1.47
0.74
1.0
1.0
—
—
—
0
0
88
753
1.17
0.74
1.5
1.5
—
—
—
0
0
37
289
1.28
0.73
1.3
1.1
—
—
—
0
0
7
38
1.84
0.73
1.0
1.0
—
—
—
0
0
59
487
1.21
0.73
1.2
1.3
11.23
12.79
u/l
0.53
53
443
5
25
2.00
0.72
1.0
1.1
—
—
—
0
0
184
1659
1.11
0.72
3.1
2.9
1.69
1.58
mg/l
0.82
163
1491
7
40
1.75
0.71
1.0
1.3
—
—
—
0
0
14
206
0.68
0.71
1.2
1.8
—
—
—
0
0
78
913
0.85
0.70
1.0
1.0
—
—
—
0
0
118
1037
1.14
0.70
1.3
1.3
109.94
120.03
u/ml
0.63
27
227
15
101
1.49
0.70
1.1
1.0
0.35
1.24
u/ml
—
9
86
89
767
1.16
0.69
1.4
1.4
23981.46
56096.94
e6/l
1.55
52
453
9
58
1.55
0.69
1.0
1.1
—
2.80
—
0
10
9
143
0.63
0.69
1.1
1.8
—
—
—
0
0
78
666
1.17
0.68
1.4
1.5
—
—
—
0
0
84
722
1.16
0.68
1.5
1.5
—
—
—
0
0
114
1003
1.14
0.68
2.0
2.1
—
—
—
0
0
35
441
0.79
0.67
2.0
2.3
409.48
504.15
e6/l
0.70
29
366
450
4235
1.07
0.66
1.4
1.3
—
—
—
0
0
36
448
0.80
0.63
3.1
3.0
—
—
—
0
0
39
314
1.24
0.63
1.1
1.3
131.26
135.66
nmol/l
0.33
39
314
10
152
0.66
0.61
1.7
1.3
—
—
—
0
0
16
113
1.42
0.61
1.1
1.3
1.76
1.82
mmol/l
—
9
72
25
191
1.31
0.60
2.0
3.7
87.38
130.06
ng/l
0.41
11
64
57
673
0.85
0.60
1.5
1.4
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
12
80
1.50
0.59
1.7
1.8
19.50
17.73
umol/l
0.16
12
80
165
1499
1.10
0.59
1.3
1.3
60.02
61.07
mmol/l
0.14
128
1190
119
1062
1.12
0.59
1.2
1.2
295.17
291.96
u/ml
0.03
72
644
78
677
1.15
0.59
2.7
2.8
32.36
30.81
mg/l
0.03
54
466
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
8
53
1.51
0.58
1.0
1.0
—
—
—
0
0
271
2523
1.08
0.57
9.6
9.8
—
—
—
0
0
6
36
1.67
0.56
1.2
1.0
—
—
—
0
0
5
88
0.57
0.56
1.2
1.4
—
—
—
0
0
97
859
1.13
0.56
1.2
1.2
—
—
—
0
0
40
329
1.22
0.55
3.5
2.4
9.90
9.39
mmol/l
0.55
40
323
91
804
1.13
0.54
4.4
5.1
7.15
7.22
mmol/l
0.07
76
663
12
82
1.46
0.54
5.9
5.1
38.67
40.15
ug/min
0.04
12
61
86
758
1.14
0.54
1.0
1.1
—
—
—
0
0
78
683
1.14
0.53
1.1
1.0
0.89
2.90
u/ml
3.27
29
286
18
134
1.34
0.52
1.1
1.2
1.43
1.79
mmol/l
—
9
79
121
1091
1.11
0.52
1.3
1.8
—
—
—
0
0
86
760
1.13
0.52
1.0
1.1
—
—
—
0
0
51
433
1.18
0.52
2.0
2.0
1.83
2.89
u/field
0.68
35
288
27
214
1.26
0.52
7.5
5.3
24.49
25.08
mmol/l
0.39
22
196
62
536
1.16
0.51
1.1
1.1
—
—
—
0
0
15
202
0.74
0.50
1.2
1.2
—
—
—
0
0
34
280
1.22
0.48
1.6
2.1
20.23
180.64
ug/l
0.91
34
261
56
646
0.87
0.48
1.4
1.4
—
—
—
0
0
442
4635
0.95
0.47
1.3
1.3
—
—
—
0
0
159
1464
1.09
0.47
2.2
2.9
—
—
—
0
0
75
663
1.13
0.47
1.4
1.6
—
—
—
0
0
131
1196
1.10
0.46
1.3
1.8
—
—
—
0
0
127
1158
1.10
0.46
1.4
1.3
—
—
—
0
0
16
120
1.33
0.46
1.3
1.4
132.20
142.24
pmol/l
0.18
16
120
87
778
1.12
0.46
3.4
3.7
—
—
—
0
0
13
94
1.38
0.45
1.1
1.1
1.93
1.60
umol/24h
0.76
13
94
17
129
1.32
0.45
4.5
2.7
—
—
—
0
0
57
496
1.15
0.45
2.5
2.1
3.43
2.40
ug/l
0.66
51
427
31
374
0.83
0.45
1.3
1.3
1.58
1.62
g/l
0.34
31
374
12
164
0.73
0.45
1.2
2.3
—
—
—
0
0
11
152
0.72
0.44
1.2
1.7
—
—
—
0
0
11
78
1.41
0.43
1.0
1.1
—
—
—
0
0
11
151
0.73
0.42
1.2
1.1
—
—
—
0
0
57
649
0.88
0.42
1.4
1.4
—
—
—
0
0
551
5303
1.04
0.41
3.6
3.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
58.55
—
0
11
58
510
1.14
0.41
2.3
2.0
6.56
3.51
ug/l
0.85
53
474
131
1207
1.09
0.40
1.3
1.8
—
—
—
0
0
21
168
1.25
0.40
1.1
1.1
—
—
—
0
0
21
168
1.25
0.40
1.4
1.4
—
—
—
0
0
129
1190
1.09
0.39
1.3
1.8
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
10
137
0.73
0.39
1.2
1.4
32.64
26.68
g/l
—
10
119
16
124
1.29
0.38
3.7
3.0
1478.50
2289.40
u/l
0.25
16
118
34
399
0.85
0.38
2.5
3.6
—
—
—
0
0
5
36
1.39
0.38
1.2
1.7
—
—
—
0
0
130
1202
1.08
0.38
1.3
1.8
—
—
—
0
0
339
3235
1.05
0.38
1.5
1.4
—
—
—
0
0
30
252
1.19
0.37
1.3
1.3
38.80
39.82
g/l
0.18
15
134
45
392
1.15
0.37
1.3
1.1
1.08
1.05
ratio
0.45
12
133
21
257
0.82
0.37
1.5
2.0
6518.58
2804.99
e6/l
0.25
12
173
81
734
1.10
0.36
2.8
3.5
57.60
57.08
%
0.07
69
602
50
440
1.14
0.36
1.1
1.1
—
—
—
0
0
29
244
1.19
0.36
1.3
3.1
53.61
966.10
mg/l
0.50
18
161
39
337
1.16
0.36
1.7
1.8
—
—
—
0
0
12
157
0.76
0.35
1.8
1.5
—
—
—
0
0
26
217
1.20
0.35
1.5
1.4
—
—
—
0
0
112
1034
1.08
0.35
2.4
2.1
22.32
24.47
mg/l
0.24
38
257
24
199
1.21
0.35
1.7
1.5
—
—
—
0
0
93
852
1.09
0.34
1.1
1.1
18.71
13132.34
iu/ml
0.57
14
187
6
44
1.36
0.34
1.0
1.1
—
—
—
0
0
24
285
0.84
0.32
1.0
1.3
—
—
—
0
0
41
466
0.88
0.32
1.2
1.1
46.88
38.24
mg/l
0.43
36
395
18
220
0.82
0.32
1.4
1.8
9193.00
19891.84
e6/l
—
8
117
204
2152
0.95
0.32
2.5
2.6
—
—
—
0
0
30
348
0.86
0.31
3.1
2.6
—
—
—
0
0
50
446
1.12
0.31
2.3
3.6
—
—
—
0
0
206
1955
1.05
0.31
2.3
2.4
3.67
3.62
g/l
0.18
198
1841
22
184
1.20
0.30
1.2
1.1
—
—
—
0
0
21
175
1.20
0.30
1.4
1.4
—
—
—
0
0
15
185
0.81
0.29
1.0
1.1
—
—
—
0
0
15
185
0.81
0.29
1.0
1.1
—
—
—
0
0
15
185
0.81
0.29
1.0
1.1
—
—
—
0
0
23
271
0.85
0.29
1.3
1.3
—
—
—
0
0
45
401
1.12
0.29
1.0
1.1
—
—
—
0
0
61
554
1.10
0.29
2.3
2.4
—
—
—
0
0
8
111
0.72
0.28
1.5
1.7
—
—
—
0
0
13
162
0.80
0.28
1.5
2.1
1051.43
429.88
e6/l
—
7
86
114
1218
0.94
0.28
1.1
1.1
—
—
—
0
0
18
216
0.83
0.28
1.4
1.8
—
—
—
0
0
30
344
0.87
0.28
1.0
1.1
—
—
—
0
0
255
2444
1.04
0.27
1.8
2.2
381.50
593.06
ug/l
0.84
230
2281
108
1010
1.07
0.27
1.1
1.1
—
—
—
0
0
57
519
1.10
0.26
1.5
2.1
10.41
10.57
%
0.09
57
519
10
77
1.30
0.26
1.5
1.5
53.10
43.34
umol/l
—
10
77
17
141
1.21
0.26
1.1
1.1
15.15
11.50
u/ml
—
9
82
41
367
1.12
0.25
1.6
1.7
—
—
—
0
0
122
1149
1.06
0.25
1.2
1.2
—
—
—
0
0
33
372
0.89
0.25
3.0
2.7
43.80
40.39
%
0.43
20
232
21
179
1.17
0.25
1.3
1.7
—
—
—
0
0
58
531
1.09
0.24
1.1
1.2
—
—
—
0
0
13
157
0.83
0.22
1.0
1.1
—
—
—
0
0
26
295
0.88
0.22
1.7
1.9
132.07
117.25
umol/l
0.10
14
172
28
316
0.89
0.22
1.1
1.0
0.53
0.86
u/ml
—
8
82
44
400
1.10
0.22
1.7
1.5
0.83
1.07
promille
0.61
34
303
124
1177
1.05
0.21
2.1
2.8
62.02
62.49
%
0.08
124
1171
17
199
0.85
0.21
1.2
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
3356.05
—
0
11
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
5
43
1.16
0.21
1.2
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
86
809
1.06
0.20
1.4
2.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
48
1.25
0.20
1.2
1.1
—
—
—
0
0
6
49
1.22
0.20
1.3
1.2
—
—
—
0
0
15
176
0.85
0.19
1.0
1.1
0.49
1.16
u/ml
—
8
89
12
99
1.21
0.19
1.1
1.3
33.43
354.78
u/l
—
7
70
17
146
1.16
0.19
1.2
1.4
—
—
—
0
0
11
90
1.22
0.19
3.3
2.7
—
32.69
—
0
13
10
81
1.23
0.18
1.0
1.0
—
—
—
0
0
10
81
1.23
0.18
1.0
1.0
—
—
—
0
0
10
81
1.23
0.18
1.0
1.0
—
—
—
0
0
28
251
1.12
0.18
1.1
1.1
459.17
671.26
ng/l
—
6
58
20
175
1.14
0.18
1.5
1.8
0.75
0.56
mmol/l
0.11
20
163
99
940
1.05
0.18
1.3
1.2
6.55
4.07
u/ml
0.47
40
390
16
138
1.16
0.17
5.6
4.9
—
—
—
0
0
47
436
1.08
0.17
1.1
1.1
—
—
—
0
0
5
67
0.75
0.17
1.0
1.1
—
—
—
0
0
61
649
0.94
0.16
2.2
2.3
1.17
1.16
e9/l
0.06
56
585
107
1119
0.96
0.16
1.4
1.7
—
—
—
0
0
14
162
0.86
0.16
1.0
1.0
—
—
—
0
0
254
2610
0.97
0.16
1.6
1.8
21.30
21.55
s
0.30
223
2272
40
370
1.08
0.15
3.0
13.1
—
—
—
0
0
15
130
1.15
0.15
1.1
1.1
—
—
—
0
0
24
216
1.11
0.15
29.3
31.4
6.67
6.94
ug/l
0.31
19
193
9
78
1.15
0.15
1.0
1.1
—
—
—
0
0
50
534
0.94
0.15
1.2
1.3
—
—
—
0
0
12
102
1.18
0.15
1.1
1.1
—
—
—
0
0
31
284
1.09
0.15
2.2
2.1
—
—
—
0
0
44
410
1.07
0.15
2.7
3.0
7.44
7.42
ph
0.63
13
154
15
131
1.15
0.14
1.8
1.5
—
—
—
0
0
33
355
0.93
0.12
1.5
1.6
—
—
—
0
0
77
804
0.96
0.12
4.9
4.4
346.90
355.03
umol/l
0.24
68
697
52
549
0.95
0.12
1.1
1.1
—
—
—
0
0
25
272
0.92
0.12
1.1
1.0
0.15
0.32
u/ml
—
7
81
49
518
0.95
0.12
1.0
1.0
661.96
696.26
ng/l
0.32
26
347
23
251
0.92
0.12
11.0
10.8
805.65
873.09
nmol/l
0.23
23
238
11
95
1.16
0.11
1.0
1.0
83.27
75.93
ug/l
0.22
11
75
59
562
1.05
0.11
1.0
1.0
0.09
0.22
u/ml
1.01
13
148
22
201
1.09
0.11
3.0
1.8
1.98
2.46
ug/l
0.48
12
117
34
318
1.07
0.11
1.1
1.0
0.43
2.18
u/ml
0.96
15
107
21
193
1.09
0.10
1.0
1.1
—
—
—
0
0
12
106
1.13
0.09
1.9
3.1
1.17
0.75
u/field
0.47
12
106
5
46
1.09
0.09
1.2
1.2
—
—
—
0
0
10
114
0.88
0.09
1.0
1.1
8.34
6.88
mg/g
—
10
105
27
252
1.07
0.09
2.3
2.7
—
—
—
0
0
49
512
0.96
0.08
1.0
1.0
337.57
356.79
ng/l
0.13
30
354
126
1291
0.98
0.08
2.2
2.6
32.49
34.14
umol/l
0.35
112
1146
23
214
1.07
0.08
1.2
1.1
—
—
—
0
0
5
61
0.82
0.08
1.0
1.1
—
—
—
0
0
43
450
0.96
0.08
1.4
1.6
71.44
77.77
umol/l
1.47
43
450
65
673
0.97
0.08
1.7
1.7
—
3.00
—
0
10
7
68
1.03
0.07
1.1
1.8
—
—
—
0
0
7
68
1.03
0.07
1.0
1.3
—
—
—
0
0
18
166
1.08
0.07
1.0
1.2
0.79
29.80
mg/l
0.50
13
121
22
235
0.94
0.07
1.0
1.1
—
—
—
0
0
38
363
1.05
0.07
2.5
2.1
48.00
75.48
ug/min
—
6
71
10
89
1.12
0.06
2.6
2.6
—
—
—
0
0
8
93
0.86
0.06
5.1
6.6
—
—
—
0
0
19
178
1.07
0.05
1.2
1.1
—
—
—
0
0
17
182
0.93
0.05
1.0
1.1
—
—
—
0
0
70
718
0.97
0.05
1.2
1.4
—
—
—
0
0
37
356
1.04
0.05
2.5
2.4
—
—
—
0
0
12
111
1.08
0.04
1.2
1.3
53.00
52.06
%
—
5
49
27
281
0.96
0.04
1.9
2.1
51.00
51.02
umol/l
0.00
22
242
11
119
0.92
0.03
1.1
1.2
—
—
—
0
0
11
119
0.92
0.03
5.4
7.5
—
—
—
0
0
20
191
1.05
0.03
1.2
1.9
—
—
—
0
0
75
738
1.02
0.03
1.4
1.3
277.80
274.28
mosm/kgh2o
0.67
55
539
35
360
0.97
0.03
1.7
1.4
1.19
1.26
nmol/l
0.16
29
277
15
158
0.95
0.02
1.1
1.4
—
—
—
0
0
53
540
0.98
0.02
1.1
1.2
33.20
33.69
mmol/l
0.06
44
455
18
172
1.05
0.02
1.3
1.3
176.20
357.27
ug/l
—
10
97
57
580
0.98
0.02
1.4
1.5
—
1250.00
—
0
8
34
332
1.02
0.01
1.1
1.5
29.79
24.45
umol/l
0.36
28
311
82
813
1.01
0.01
1.2
1.3
—
—
—
0
0
20
194
1.03
0.00
1.7
1.7
—
—
—
0
0
15
146
1.03
0.00
3.9
5.6
—
—
—
0
0
24
241
1.00
0.00
1.2
1.4
53.45
54.28
%
0.03
19
209
106
1055
1.00
0.00
1.1
1.1
—
—
—
0
0
20
201
1.00
0.00
1.8
1.6
9.43
8.69
ug/l
0.40
20
201
56
560
1.00
0.00
3.4
2.3
—
—
—
0
0
98
980
1.00
0.00
1.2
1.2
—
—
—
0
0
22
215
1.02
0.00
1.2
1.1
—
—
—
0
0
52
524
0.99
0.00
1.4
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.2
—
—
—
0
0
7
77
0.91
-0.00
1.3
2.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
10.11
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
77
0.91
-0.00
1.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
-0.00
1.2
1.4
181.60
154.09
mmol/l
—
5
49
8
84
0.95
-0.00
12.9
8.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.6
—
—
—
0
0
6
69
0.87
-0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
33.80
—
0
5

Mortality – FinRegistry

Association

Association between endpoint E4_GOITREMULTINOD and mortality.

Females

Parameter HR [95% CI] p-value
E4_GOITREMULTINOD 0.943 [0.87, 1.02] 0.167
Birth year 0.992 [0.98, 1.0] 0.055

During the follow-up period (1.1.1998 — 31.12.2019), 3745 out of 27526 females with E4_GOITREMULTINOD died.

Males

Parameter HR [95% CI] p-value
E4_GOITREMULTINOD 0.966 [0.87, 1.07] 0.519
Birth year 0.987 [0.98, 1.0] 0.014

During the follow-up period (1.1.1998 — 31.12.2019), 982 out of 5001 males with E4_GOITREMULTINOD died.

Mortality risk

Mortality risk for people of age

years, who have E4_GOITREMULTINOD.

N-year risk Females Males
1 0.095% 0.187%
5 0.505% 1.23%
10 1.242% 2.97%
15 2.22% 5.37%
20 4.119% 8.844%

Relationships between endpoints

Index endpoint: E4_GOITREMULTINOD – Nontoxic multinodular goitre

GWS hits: 56

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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