No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1242 |
4. Check minimum number of eventsNone |
1242 |
5. Include endpointsNone |
1242 |
6. Filter based on genotype QC (FinnGen only) |
1242 |
Control definitions (FinnGen only)
- Control exclude
- AB1_SEXUAL_TRANSMISSION
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Gonococcal infection
based on the number of shared cases.
Similar with more cases:
- Infections with a predominantly sexual mode of transmission
- Certain infectious and parasitic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8919 | 6018 | 2796 |
| Only index persons | 8042 | 5459 | 2583 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.14 | 0.17 | 0.08 |
| Only index persons | 0.17 | 0.20 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 25.79 | 23.82 | 29.81 |
| Only index persons | 25.63 | 23.67 | 29.77 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1242 | 832 | 410 |
| Unadjusted period prevalence (%) | 0.25 | 0.28 | 0.18 |
| Median age at first event (years) | 26.55 | 22.99 | 33.78 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1120
- Matched controls
- 11201
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A54.0
ICD-10 Finland
Gonococcal infection of lower genitourinary tract without periurethral or accessory gland abscess
2305.9
216.9
203
*
A54.5
ICD-10 Finland
Gonococcal pharyngitis
1791.4
160.4
152
*
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
13.9
153.2
280
263
09801
ICD-8 Finland
Gonococcal infections, Urethritis acuta cum salpingo-cophoritide
+∞
152.7
143
*
09808
ICD-8 Finland
Gonococcal infections, Uro-genitalis acuta, alia
+∞
148.3
139
*
09809
ICD-8 Finland
Gonococcal infections, Uro-genitalis (acuta) NUD
+∞
136.3
128
*
A54.6
ICD-10 Finland
Gonococcal infection of anus and rectum
+∞
127.6
120
*
A56.3
ICD-10 Finland
Chlamydial infection of anus and rectum
+∞
126.5
119
*
A56.0
ICD-10 Finland
Chlamydial infection of lower genitourinary tract
77.2
110.1
124
18
09802
ICD-8 Finland
Gonococcal infections, Urethritis acuta cum bartholinitide
+∞
86.6
82
*
B23.1
ICD-10 Finland
HIV disease resulting in (persistent) generalized lymphadenopathy
119.6
72.9
78
7
09811
ICD-8 Finland
Gonococcal infections, Salpingo-cophoritis chronica
+∞
68.4
65
*
A63.0
ICD-10 Finland
Anogenital (venereal) warts
33.5
61.8
81
26
A51.0
ICD-10 Finland
Primary genital syphilis
+∞
59.9
57
*
09800
ICD-8 Finland
Gonococcal infections, Urethritis acuta cum cervicitide
+∞
58.9
56
*
Z29.2
ICD-10 Finland
Other prophylactic chemotherapy
284.3
53.6
54
*
WW200
NOMESCO Finland
Immunization
10.9
52.8
104
104
Y25
ICPC
Fear sexually transm disease male
9.5
50.7
108
125
0981A
ICD-9 Finland
Gonococcal infections, Acute, of upper genito-urinary tract
+∞
50.4
48
*
Z21
ICD-10 Finland
Asymptomatic human immunodeficiency virus [HIV] infection status
379.4
37.2
37
*
64199
ICD-8 Finland
Abortion induced for other legal indications, Without mention of sepsis or toxaemia
3.6
34.7
175
554
B24
ICD-10 Finland
Unspecified human immunodeficiency virus [HIV] disease
72.0
31.0
35
5
A56.4
ICD-10 Finland
Chlamydial infection of pharynx
+∞
29.3
28
*
A51.9
ICD-10 Finland
Early syphilis, unspecified
+∞
28.2
27
*
13199
ICD-8 Finland
Trichomoniasis urogenitalis, Unspecified
+∞
26.1
25
*
64091
ICD-8 Finland
Medical termination of pregnancy, Weakness (medical-social reason)
3.7
24.3
113
332
0980A
ICD-9 Finland
Gonococcal infections, Acute, of lower genito-urinary tract
+∞
24.0
23
*
A51.3
ICD-10 Finland
Secondary syphilis of skin and mucous membranes
+∞
23.0
22
*
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.7
21.8
100
290
A60.0
ICD-10 Finland
Herpesviral infection of genitalia and urogenital tract
21.2
21.3
31
15
09806
ICD-8 Finland
Gonococcal infections, Uro-genitalis acuta, suspecta
+∞
20.9
20
*
09888
ICD-8 Finland
Gonococcal infections, Of other sites
+∞
19.8
19
*
Y71
ICPC
Gonorrhoea male
+∞
18.8
18
*
P01AB01
ATC
metronidazole; oral, rectal
1.8
17.4
473
3286
61207
ICD-8 Finland
Acute salpingitis and oophoritis, suspecta
8.7
17.3
37
44
A53.9
ICD-10 Finland
Syphilis, unspecified
+∞
16.7
16
*
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.9
16.4
107
399
R03BB04
ATC
tiotropium bromide; inhalant
2.7
14.4
101
397
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
4.6
14.1
49
111
N05BA04
ATC
oxazepam; oral
1.8
13.3
278
1751
A55
ICD-10 Finland
Chlamydial lymphogranuloma (venereum)
+∞
12.5
12
*
09839
ICD-8 Finland
Gonococcal infections, Of joint
+∞
12.5
12
*
A54.9
ICD-10 Finland
Gonococcal infection, unspecified
+∞
12.5
12
*
J05AB01
ATC
aciclovir; systemic
1.8
12.5
234
1418
Z71.8
ICD-10 Finland
Other specified counselling
1.8
12.4
269
1708
R03AC02
ATC
salbutamol; inhalant
1.6
12.3
575
4489
B23.8
ICD-10 Finland
HIV disease resulting in other specified conditions
47.2
11.9
14
*
N05CF01
ATC
zopiclone; oral
1.7
11.8
332
2269
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.3
11.6
107
486
61200
ICD-8 Finland
NA
13.8
11.5
19
14
N05BA01
ATC
diazepam; systemic, rectal
2.0
11.4
152
812
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
5.4
11.2
33
63
D06BB04
ATC
podophyllotoxin; topical
3.1
11.2
61
205
D01
ICPC
Abdominal pain/cramps general
2.2
10.9
114
551
X23
ICPC
Fear sexually transm dis female
4.0
10.8
42
108
J20
ICD-10 Finland
Acute bronchitis
2.2
10.7
111
534
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
10.6
368
2641
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
10.5
403
2965
09992
ICD-8 Finland
Other veneral disease, Condyloma acuminatum
+∞
10.4
10
*
R74
ICPC
Upper respiratory infection acute
1.6
10.4
316
2188
M79.6
ICD-10 Finland
Pain in limb
1.6
10.4
375
2714
61208
ICD-8 Finland
Acute salpingitis and oophoritis, Alia definita
7.6
10.2
23
31
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.9
10.1
60
214
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
2.3
10.1
89
397
N07BA03
ATC
varenicline; oral
2.5
9.9
76
315
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.5
9.7
75
310
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
9.7
266
1790
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
9.5
411
3088
09899
ICD-8 Finland
Gonococcal infections, Site unspecified
+∞
9.4
9
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
9.2
492
3869
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
6.8
9.2
22
33
R95
ICPC
Chron obstructive pulmonary disease
4.4
9.1
32
75
6350C
ICD-9 Finland
Legally induced abortion, Complicated by genital tract and pelvic infection[ABORTUS PROV LEGAL SINE COMPL,SOSIAALISET SYYT]
2.5
9.1
74
314
64099
ICD-8 Finland
Abortion induced for medical indications, Without mention of sepsis or toxaemia
4.5
9.1
31
71
R06.0
ICD-10 Finland
Dyspnoea
1.7
9.0
226
1480
D11
ICPC
Diarrhoea
2.0
9.0
125
677
0769C
ICD-9 Finland
Trachoma, unspecified[CHLAMYDIA ENDOMETRITIS ET SALPINGO-OOPHORITIS]
24.2
8.9
12
5
Z20.2
ICD-10 Finland
Contact with and exposure to infections with a predominantly sexual mode of transmission
3.8
8.9
36
97
30180
ICD-8 Finland
Personality disorders, Immatura
9.6
8.8
17
18
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
8.8
215
1399
J01AA02
ATC
doxycycline; systemic
1.5
8.8
833
7345
N06AX21
ATC
duloxetine; oral
1.9
8.7
127
700
J01DA01
ATC
[U] cefalexin; systemic
1.5
8.7
665
5597
N06AB03
ATC
fluoxetine; oral
1.8
8.7
143
824
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
4.8
8.6
27
57
N06AX11
ATC
mirtazapine; oral
1.5
8.5
332
2426
Z20.6
ICD-10 Finland
Contact with and exposure to human immunodeficiency virus [HIV]
20.2
8.5
12
6
N06AB04
ATC
citalopram; systemic
1.6
8.4
233
1567
F32.1
ICD-10 Finland
Moderate depressive episode
2.4
8.4
67
285
A51.5
ICD-10 Finland
Early syphilis, latent
+∞
8.3
8
*
J05AB11
ATC
valaciclovir; oral
1.8
8.3
135
774
61510
ICD-8 Finland
Other diseases of ovary and Fallopian tube, Hydrosalpinx
9.5
8.3
16
17
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
8.3
133
761
TAB00
NOMESCO Finland
Lumbar puncture
2.6
8.1
57
227
N06AX16
ATC
venlafaxine; oral
1.7
8.1
160
979
B37.4
ICD-10 Finland
Candidiasis of other urogenital sites
17.3
8.1
12
7
N02AX02
ATC
tramadol; systemic, rectal
1.5
8.1
414
3199
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
8.0
142
837
N05AH04
ATC
quetiapine; oral
1.7
8.0
171
1069
QXA50
NOMESCO Finland
Skin cryotherapy, unspecified location
13.1
7.9
13
10
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.2
7.9
77
361
R4110
NOMESCO Finland
Physiotherapy
1.5
7.9
275
1954
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
7.7
163
1015
B23.0
ICD-10 Finland
Acute HIV infection syndrome
45.3
7.7
9
*
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
3.5
7.6
33
95
61201
ICD-8 Finland
Acute salpingitis and oophoritis, Pyosalpinx acuta
8.1
7.6
16
20
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.3
7.6
70
319
B17.1
ICD-10 Finland
Acute hepatitis C
25.2
7.6
10
*
R05
ICPC
Cough
1.6
7.6
219
1487
M54.5
ICD-10 Finland
Low back pain
1.5
7.5
333
2488
R53
ICD-10 Finland
Malaise and fatigue
1.7
7.5
176
1130
N03AX16
ATC
pregabalin; oral
1.6
7.5
236
1634
A52.1
ICD-10 Finland
Symptomatic neurosyphilis
80.6
7.4
8
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
7.4
104
568
N06AB10
ATC
escitalopram; oral
1.6
7.3
215
1462
09810
ICD-8 Finland
Gonococcal infections, Cervicitis chronica
+∞
7.3
7
*
Y04.0
ICD-10 Finland
Assault by bodily force by spouse or partner
9.4
7.3
14
15
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
3.4
7.3
33
99
K05.31
ICD-10 Finland
Periodontitis pronounced
1.9
7.2
102
560
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
4.6
7.1
23
51
62200
ICD-8 Finland
Infective diseases of uterus (except cervix), vagina and vulva, Endometritis acuta
5.7
7.1
19
34
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
7.1
237
1662
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
7.1
274
1989
78551
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Symptomata abdominalis acuta NUD
2.7
7.1
45
168
M03BC01
ATC
orphenadrine (citrate); systemic
1.5
7.0
252
1796
J01DB01
ATC
cefalexin; oral
1.5
6.9
871
7882
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.7
6.9
44
165
R51.80
ICD-10 Finland
Headache
1.7
6.9
150
942
N48.1
ICD-10 Finland
Balanoposthitis
4.0
6.7
25
64
ZX114
NOMESCO Finland
Intramuscular
3.7
6.7
27
74
N07BB01
ATC
disulfiram; oral
2.4
6.6
53
228
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.0
6.5
75
380
N70.1
ICD-10 Finland
Chronic salpingitis and oophoritis
4.1
6.4
23
57
WX110
NOMESCO Finland
Local anesthesy
1.4
6.4
727
6396
N34.1
ICD-10 Finland
Nonspecific urethritis
11.1
6.3
11
10
A03.3
ICD-10 Finland
Shigellosis due to Shigella sonnei
+∞
6.3
6
*
R02
ICPC
Shortness of breath/dyspnoea
1.8
6.2
107
627
AA1AD
NOMESCO Finland
CT of head and brain
1.5
6.2
199
1379
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
4.0
6.2
23
59
P01
ICPC
Feeling anxious/nervous/tense
1.8
6.2
106
618
F10.01
ICD-10 Finland
Alcohol-related acute intoxication with permanent or other somatic damage
6.3
6.2
15
24
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.9
6.2
88
484
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.8
6.1
106
624
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.6
6.1
149
967
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
6.1
104
609
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.4
6.1
47
199
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
281
9
405.01
290.04
3.1
1.6
—
—
—
0
0
340
396
11.45
282.03
10.8
1.6
—
—
—
0
0
349
497
9.38
245.83
11.0
1.7
—
—
—
0
0
104
48
23.56
142.10
13.9
5.2
2768.8
104.4
u/ml
—
64
9
388
1020
5.08
141.61
7.6
1.8
—
—
—
0
0
400
1123
4.78
133.80
8.7
1.9
—
—
—
0
0
82
57
15.33
91.97
2.6
2.7
30.6
42.9
%
2.02
14
16
78
70
11.82
74.98
2.1
2.1
684.9
739.4
e6/l
—
8
26
239
964
2.83
41.17
2.2
2.3
30.0
90.2
u/l
0.66
210
832
426
2450
2.12
32.32
3.1
2.8
0.4
0.4
e6/l
0.24
296
1787
244
1155
2.38
29.47
8.4
5.1
1.0
1.0
mmol/l
2.66
232
1061
273
1503
2.05
22.06
2.7
2.5
1.0
1.1
e6/l
0.37
136
811
48
101
4.90
21.65
1.1
1.1
—
—
—
0
0
96
331
3.06
21.50
1.5
1.3
—
—
—
0
0
51
116
4.54
20.95
1.8
1.2
—
—
—
0
0
253
1398
2.02
20.06
2.7
2.5
3.1
2.9
e6/l
0.08
117
707
769
5969
1.76
19.78
10.1
9.4
4.0
3.9
e9/l
0.35
650
5266
694
5247
1.73
19.48
6.2
6.1
10.2
10.8
umol/l
0.64
657
4986
92
335
2.89
18.69
2.3
1.7
—
—
—
0
0
499
3473
1.73
18.67
5.2
3.1
30.3
32.2
u/l
0.93
482
3312
92
358
2.70
16.48
1.3
1.3
178.6
225.6
miu/ml
0.63
41
166
551
4064
1.64
15.76
4.4
4.5
36.5
36.2
g/l
0.50
518
3806
288
1799
1.78
15.22
2.7
2.4
7.4
6.3
e6/l
0.48
247
1580
710
5629
1.61
14.73
4.7
4.5
6.5
6.6
mmol/l
1.21
671
5261
926
7888
1.68
13.96
8.3
7.4
79.5
77.3
u/l
0.65
873
7432
1012
8836
1.78
13.90
18.9
14.9
13.6
13.6
%
0.05
993
8643
622
4881
1.55
12.72
3.6
3.4
0.0
0.0
estimate
0.50
118
867
1112
10068
2.00
12.68
14.5
11.1
87.3
85.1
ml/min/173m2
3.03
920
8219
227
1407
1.75
12.06
1.8
1.9
1.5
1.4
%
0.39
195
1268
626
4956
1.53
12.05
3.6
3.4
0.0
0.0
estimate
1.08
114
853
620
4919
1.52
11.68
5.1
4.6
0.0
0.0
estimate
0.00
117
889
164
950
1.84
10.88
3.0
3.1
—
—
—
0
0
551
4321
1.49
10.64
5.5
5.5
1.2
1.2
mmol/l
0.31
516
3926
35
104
3.43
10.05
1.1
1.2
—
—
—
0
0
293
2035
1.58
9.81
1.9
1.5
—
—
—
0
0
214
1384
1.66
9.58
1.8
1.8
—
—
—
0
0
390
2904
1.50
9.43
1.8
1.7
1.5
1.4
mmol/l
0.22
330
2467
177
1104
1.70
9.06
2.5
2.8
8.6
7.3
umol/l
0.31
147
959
28
77
3.70
9.02
1.9
1.7
—
—
—
0
0
1127
10459
1.84
8.90
15.4
12.1
26.9
21.5
mg/l
4.58
916
8077
70
322
2.24
8.80
1.3
1.1
—
—
—
0
0
70
324
2.23
8.68
1.3
1.1
—
—
—
0
0
159
977
1.72
8.58
1.7
1.7
—
—
—
0
0
470
3698
1.44
8.32
2.0
1.8
97.0
97.8
pmol/l
0.12
237
1809
274
1954
1.52
7.96
1.6
1.5
23.0
21.7
nmol/l
0.16
239
1684
105
583
1.88
7.95
1.6
1.3
—
—
—
0
0
25
71
3.57
7.72
1.8
2.0
—
—
—
0
0
157
994
1.66
7.56
1.7
1.7
—
—
—
0
0
13
22
5.96
7.39
1.1
1.3
—
—
—
0
0
12
19
6.37
7.25
1.0
1.2
—
—
—
0
0
140
875
1.68
7.08
1.8
2.2
0.2
0.2
g/l
0.01
131
827
811
7138
1.39
6.94
3.5
2.9
—
—
—
0
0
571
4753
1.37
6.89
6.4
6.3
1.2
1.2
mmol/l
0.28
489
4036
41
174
2.40
6.27
1.4
1.3
—
—
—
0
0
41
174
2.40
6.27
1.4
1.3
—
—
—
0
0
22
68
3.28
6.02
1.7
1.8
—
—
—
0
0
313
2411
1.40
5.87
1.3
1.3
1.9
1.8
u/ml
0.04
58
647
15
36
4.21
5.83
1.0
1.3
—
—
—
0
0
211
1515
1.47
5.80
2.9
3.5
0.8
0.8
mmol/l
0.42
195
1423
84
482
1.80
5.77
1.8
1.6
—
—
—
0
0
1036
9632
1.46
5.64
5.1
4.7
1.8
2.3
mu/l
1.28
973
8892
364
2896
1.36
5.56
2.1
2.1
176.9
205.9
u/l
0.41
346
2733
190
1356
1.47
5.37
1.9
2.3
125.3
132.9
ug/g
0.13
149
1080
51
254
2.05
5.35
1.3
1.5
—
—
—
0
0
1128
10704
1.59
5.23
16.1
13.3
139.5
139.8
mmol/l
5.50
1104
10418
19
59
3.25
5.18
1.3
1.1
—
—
—
0
0
229
1705
1.42
5.16
2.6
2.9
2.5
2.5
mmol/l
0.47
194
1507
33
141
2.38
5.02
2.2
1.8
—
—
—
0
0
72
412
1.79
5.02
2.2
3.2
24.2
24.5
mmol/l
0.33
67
371
100
629
1.64
4.97
1.5
1.5
—
—
—
0
0
288
2247
1.37
4.90
1.8
1.9
1.1
1.0
mg/l
0.40
206
1674
184
1332
1.45
4.82
2.0
2.1
29.2
29.5
s
0.46
178
1290
1128
10740
1.55
4.73
16.2
13.4
3.9
3.9
mmol/l
1.30
1099
10439
291
2297
1.35
4.56
2.6
2.2
—
—
—
0
0
837
7627
1.30
4.40
4.5
4.0
13.1
11.2
mm/h
2.84
788
7090
36
171
2.14
4.32
2.6
2.3
16.4
16.7
%
0.13
18
81
24
96
2.53
4.23
1.7
1.4
—
—
—
0
0
1047
9871
1.39
4.21
17.9
12.8
41.1
40.5
%
2.54
833
7493
228
1753
1.37
4.21
4.0
3.4
200.1
471.2
ng/l
1.31
162
1246
91
593
1.58
3.95
2.4
3.1
265.8
136.6
ng/l
0.64
80
533
194
1469
1.38
3.93
1.8
1.7
1118.4
1228.2
nmol/l
0.93
145
1106
36
178
2.05
3.92
2.1
2.1
132.0
131.9
g/l
0.01
23
128
85
555
1.57
3.68
1.1
1.0
—
—
—
0
0
136
991
1.42
3.46
7.0
8.0
1.3
1.2
mmol/l
0.13
114
803
34
174
1.98
3.41
1.4
1.4
—
—
—
0
0
103
718
1.47
3.31
4.7
7.6
7.8
8.2
mmol/l
0.23
96
684
34
176
1.96
3.31
1.7
1.7
—
—
—
0
0
1170
11341
1.55
3.24
12.5
9.9
27.8
27.7
u/l
0.08
1138
10979
877
8164
1.25
3.23
4.3
4.1
14.7
14.8
pmol/l
0.73
811
7481
44
253
1.77
3.12
1.7
1.3
17.7
21.1
e6/l
0.13
34
190
44
253
1.77
3.12
1.7
1.3
2736.8
2058.3
e6/l
0.09
34
200
492
4324
1.23
3.08
2.3
2.2
75.1
77.3
nmol/l
1.00
457
3931
129
958
1.39
2.96
3.3
5.0
209.4
250.2
u/l
3.95
118
915
13
46
2.85
2.92
1.6
2.3
59.9
178.0
umol/l
—
8
25
19
397
0.47
2.82
1.4
1.5
—
—
—
0
0
15
59
2.56
2.79
1.1
1.1
—
—
—
0
0
53
332
1.62
2.78
1.5
1.6
0.0
0.1
iu/ml
0.87
18
47
468
4125
1.22
2.78
2.8
2.6
126.3
119.3
ug/l
0.11
419
3838
253
2100
1.26
2.63
2.1
2.1
2.7
3.0
mg/l
1.20
208
1799
110
817
1.38
2.55
2.9
2.4
72.0
69.8
ml/min/173m2
0.23
45
319
296
2509
1.24
2.55
2.4
2.3
3492.7
4423.3
umol/l
0.15
254
2204
42
258
1.65
2.41
2.2
2.4
—
—
—
0
0
9
27
3.35
2.39
4.2
2.6
—
—
—
0
0
12
46
2.62
2.36
2.6
1.7
—
—
—
0
0
93
681
1.40
2.36
2.4
2.5
66.2
67.4
g/l
0.65
83
628
271
2295
1.23
2.34
2.3
2.8
977.2
835.2
ng/l
0.33
223
1899
379
3319
1.20
2.34
3.0
3.4
2.4
2.4
mmol/l
0.16
338
2944
507
4566
1.19
2.28
3.8
3.7
—
—
—
0
0
787
7360
1.19
2.27
3.4
3.0
50.2
46.1
u/l
0.64
746
6911
84
1139
0.72
2.27
1.6
1.7
—
—
—
0
0
53
351
1.53
2.25
1.5
1.9
1.6
1.6
g/l
0.08
46
312
1005
9622
1.23
2.22
5.7
5.2
38.3
39.2
mmol/mol
2.50
950
8993
16
73
2.21
2.21
1.8
1.9
15.6
13.2
%
—
7
31
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
36
218
1.67
2.20
2.2
4.0
0.3
0.4
u/ml
0.74
12
120
357
3125
1.20
2.20
2.6
2.5
55.0
57.9
u/l
0.47
328
2889
1208
11871
1.64
2.19
22.6
17.8
263.7
257.5
e9/l
2.71
1173
11585
83
610
1.39
2.09
2.2
2.6
4.5
4.6
kpa
0.01
78
589
21
110
1.92
2.06
1.0
1.1
—
—
—
0
0
100
761
1.34
2.03
2.5
3.2
5.9
5.9
kpa
0.05
95
739
41
263
1.58
2.02
1.2
1.2
3.7
3.7
mmol/l
0.21
36
252
1208
11883
1.61
2.02
22.6
17.8
4.5
4.6
e12/l
5.34
1174
11564
11
44
2.51
2.01
3.3
3.6
871.9
907.3
u/ml
0.03
11
44
1208
11885
1.60
1.99
22.6
17.8
6.8
6.5
e9/l
7.89
1173
11570
98
748
1.34
1.96
2.5
3.3
2.2
2.1
mmol/l
0.10
81
617
5
11
4.56
1.94
1.6
1.7
55.4
103.6
ng/l
—
5
11
1208
11889
1.59
1.93
22.7
17.8
135.9
137.3
g/l
2.63
1194
11724
21
113
1.87
1.92
4.6
6.4
11.1
11.2
mg/l
0.02
16
105
43
283
1.54
1.92
1.5
1.4
229.2
301.3
ug/g
1.39
25
159
14
65
2.17
1.88
1.1
1.1
—
—
—
0
0
44
295
1.51
1.82
1.6
1.6
0.2
0.2
g/l
0.65
38
282
36
233
1.56
1.75
1.6
1.7
8180.3
12756.5
e6/l
0.56
25
169
23
133
1.74
1.70
1.0
1.1
—
—
—
0
0
35
228
1.55
1.66
1.2
1.2
—
—
—
0
0
214
1832
1.20
1.66
1.3
1.3
13.5
9.8
u/ml
0.27
70
760
16
83
1.94
1.65
1.0
1.1
—
—
—
0
0
16
83
1.94
1.65
1.0
1.1
—
—
—
0
0
14
69
2.04
1.65
2.5
1.9
—
—
—
0
0
39
261
1.51
1.65
2.2
1.7
38.1
38.6
g/l
0.16
30
233
16
84
1.92
1.60
1.0
1.1
—
—
—
0
0
16
84
1.92
1.60
1.0
1.1
—
—
—
0
0
16
84
1.92
1.60
1.0
1.1
—
—
—
0
0
38
255
1.51
1.59
2.3
1.8
0.0
0.0
g/l
0.50
32
241
1053
10214
1.20
1.57
4.8
4.2
5.9
5.9
mmol/l
0.31
969
9420
13
64
2.04
1.54
1.5
1.5
3.8
6.5
u/l
—
8
33
44
307
1.45
1.53
1.6
1.6
1.1
1.2
g/l
1.72
38
292
43
300
1.45
1.50
1.1
1.1
—
—
—
0
0
341
3061
1.16
1.50
3.4
3.2
7.1
7.5
mmol/l
0.71
283
2623
18
101
1.79
1.49
1.1
1.1
56.6
55.1
u/l
0.04
12
72
35
236
1.50
1.45
2.4
1.8
0.0
0.0
g/l
0.00
29
222
17
95
1.80
1.43
1.8
1.4
1.4
1.3
promille
0.18
12
75
21
127
1.66
1.37
1.1
1.5
—
—
—
0
0
21
127
1.66
1.37
1.1
1.5
—
—
—
0
0
21
127
1.66
1.37
1.1
1.4
—
—
—
0
0
21
127
1.66
1.37
1.1
1.4
—
—
—
0
0
6
23
2.62
1.37
1.2
1.2
—
—
—
0
0
117
964
1.24
1.35
3.4
4.3
10.7
11.8
ug/l
0.06
89
783
101
1236
0.80
1.35
4.7
4.3
31.7
31.9
%
0.08
78
833
34
234
1.47
1.30
2.4
1.8
0.0
0.0
g/l
0.00
28
221
159
1358
1.20
1.29
2.4
2.3
12.4
14.0
umol/l
2.05
147
1258
86
689
1.27
1.28
2.2
2.3
14.8
14.0
nmol/l
0.38
78
639
9
44
2.05
1.27
1.1
1.2
—
—
—
0
0
136
1149
1.21
1.25
2.5
2.3
20.9
24.1
%
2.05
124
995
9
45
2.01
1.23
1.1
1.2
—
—
—
0
0
48
358
1.35
1.20
1.5
1.4
34.3
31.4
iu/l
0.22
42
302
18
109
1.66
1.19
1.5
1.7
39.6
64.0
%
1.51
12
69
12
64
1.88
1.18
1.1
1.1
—
—
—
0
0
95
779
1.24
1.17
1.2
1.2
112.6
146.5
iu/ml
0.46
27
309
34
241
1.42
1.14
3.4
3.3
40.2
82.0
mg/l
0.69
26
192
382
3515
1.13
1.14
3.5
3.1
48.6
41.5
ng/l
0.12
224
2219
39
284
1.39
1.13
2.4
2.0
1.1
0.8
g/l
0.15
32
259
90
737
1.24
1.13
3.4
3.2
83.8
76.4
ng/l
0.41
77
656
64
503
1.29
1.13
1.4
1.4
—
—
—
0
0
46
345
1.35
1.12
1.9
1.9
33.0
37.5
nmol/l
1.07
46
338
21
135
1.57
1.11
1.0
1.3
—
—
—
0
0
42
311
1.36
1.11
2.2
1.9
3.0
3.1
g/l
0.06
32
253
15
89
1.69
1.08
1.3
1.4
519219.6
84673.7
e6/l
—
7
65
102
1206
0.83
1.01
6.8
5.9
—
—
—
0
0
9
48
1.88
1.00
1.1
1.9
1.2
8.2
nmol/l
—
9
43
285
2598
1.13
0.99
4.2
3.7
0.0
0.0
estimate
0.80
112
880
33
241
1.38
0.97
3.5
3.3
33.5
40.7
mg/l
0.18
26
192
15
92
1.64
0.97
1.1
1.2
—
—
—
0
0
42
320
1.32
0.95
1.4
1.3
—
—
—
0
0
7
37
1.90
0.94
3.1
2.0
48.7
57.5
ug/l
—
7
37
34
252
1.36
0.92
1.4
1.4
—
—
—
0
0
6
29
2.07
0.89
1.0
1.1
—
—
—
0
0
13
79
1.65
0.88
1.3
1.1
—
—
—
0
0
21
144
1.47
0.87
1.2
1.5
—
—
—
0
0
6
30
2.00
0.87
1.0
1.1
—
—
—
0
0
6
30
2.00
0.87
1.2
1.1
—
—
—
0
0
141
1241
1.15
0.85
2.4
2.2
2.4
2.4
g/l
0.15
130
1147
6
31
1.94
0.84
1.2
1.1
—
—
—
0
0
27
197
1.38
0.82
1.1
1.2
85.8
103.7
u/ml
—
5
41
13
81
1.61
0.81
1.3
1.2
—
—
—
0
0
39
303
1.30
0.80
2.3
1.9
10.2
10.3
g/l
0.05
31
271
42
331
1.28
0.78
2.2
1.8
8.0
7.4
g/l
1.24
32
262
42
331
1.28
0.78
2.2
1.8
—
—
—
0
0
42
331
1.28
0.78
2.2
1.8
3.8
3.7
g/l
0.13
31
247
7
38
1.85
0.73
1.0
1.1
290.1
173.9
iu/ml
—
7
38
83
711
1.18
0.72
2.2
2.2
6.0
7.9
ug/l
0.95
69
644
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
11
68
1.62
0.71
1.3
1.1
—
—
—
0
0
12
76
1.58
0.71
2.6
2.3
—
—
—
0
0
7
40
1.75
0.71
1.1
1.2
—
—
—
0
0
7
40
1.75
0.71
1.1
1.2
—
—
—
0
0
23
169
1.37
0.69
1.3
1.2
—
—
—
0
0
21
152
1.39
0.69
1.0
1.1
3.0
2.2
u/ml
—
6
71
29
375
0.77
0.69
3.1
3.1
26.0
25.4
mmol/l
0.32
29
365
90
780
1.17
0.69
3.1
3.6
1.2
1.2
mmol/l
1.23
77
679
13
85
1.54
0.69
1.4
1.4
71.8
49.2
pmol/l
—
5
25
211
1935
1.11
0.68
1.3
1.3
51.7
30.7
iu/ml
0.79
61
631
5
27
1.86
0.68
1.0
1.3
—
—
—
0
0
5
27
1.86
0.68
1.0
1.1
—
90.4
—
0
14
5
93
0.54
0.67
7.2
1.5
—
—
—
0
0
5
28
1.79
0.66
1.0
1.0
—
—
—
0
0
28
215
1.31
0.65
1.3
1.3
—
—
—
0
0
5
29
1.73
0.64
1.0
1.0
—
83.9
—
0
15
13
87
1.50
0.63
1.1
1.3
—
—
—
0
0
40
489
0.81
0.62
2.5
2.9
126.8
132.1
g/l
0.87
40
477
6
105
0.57
0.61
6.2
1.4
—
—
—
0
0
5
30
1.67
0.61
1.2
1.0
—
—
—
0
0
109
969
1.14
0.61
2.2
2.3
0.7
0.6
ug/l
0.13
77
488
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
38
308
1.24
0.60
2.1
2.0
0.6
1.9
ug/l
0.90
32
283
8
53
1.51
0.58
1.1
1.2
—
—
—
0
0
6
36
1.67
0.56
1.2
1.6
—
—
—
0
0
203
1886
1.09
0.53
1.6
1.6
473.4
31372991.0
pmol/l
1.72
173
1581
12
168
0.71
0.50
2.4
2.5
1.2
1.5
mmol/l
1.96
12
163
28
225
1.25
0.49
1.2
1.2
—
—
—
0
0
115
1045
1.11
0.48
13.0
17.4
1.1
1.2
inr
0.17
11
155
13
177
0.73
0.47
1.3
1.2
2.2
6.1
u/ml
—
5
55
10
68
1.47
0.47
1.0
1.1
—
—
—
0
0
8
120
0.66
0.45
1.0
1.0
—
—
—
0
0
14
186
0.75
0.44
1.0
1.1
71.2
131.0
iu/ml
—
5
41
9
127
0.71
0.43
1.1
1.4
—
—
—
0
0
1039
10260
1.08
0.43
4.0
3.8
1.4
1.3
mmol/l
2.83
964
9519
5
32
1.56
0.42
2.0
1.9
—
—
—
0
0
0
17
0.00
0.40
0.0
2.8
—
1.5
—
0
11
5
35
1.43
0.39
4.8
2.1
—
—
—
0
0
36
420
0.85
0.39
1.3
1.8
—
—
—
0
0
40
462
0.86
0.38
1.5
2.2
40.5
39.3
u/l
0.14
35
421
9
67
1.35
0.38
1.0
1.3
—
—
—
0
0
33
280
1.18
0.38
1.2
1.2
—
—
—
0
0
9
68
1.33
0.37
1.0
1.4
—
—
—
0
0
396
3819
1.05
0.37
3.9
3.5
—
—
—
0
0
9
70
1.29
0.36
1.6
2.4
—
—
—
0
0
13
99
1.32
0.35
4.2
2.5
33.1
32.5
pg
0.20
13
99
25
209
1.20
0.34
1.2
1.1
0.2
1.6
u/ml
3.67
12
84
10
133
0.75
0.33
1.0
1.0
—
—
—
0
0
41
359
1.15
0.33
3.1
3.2
638.8
497.9
u/ml
0.08
29
305
74
674
1.10
0.33
1.3
1.3
29.5
40.6
au/ml
—
5
37
39
341
1.15
0.32
1.7
1.8
—
—
—
0
0
6
47
1.28
0.32
1.0
1.0
1894.5
1731.6
miu/ml
—
6
47
1052
10617
0.94
0.32
4.7
4.2
1.5
1.5
mmol/l
2.35
977
9897
15
185
0.81
0.30
1.2
1.7
—
—
—
0
0
56
506
1.11
0.29
4.1
2.9
2.0
1.8
mmol/l
0.19
48
379
25
213
1.18
0.29
1.1
1.2
223.4
234.5
u/ml
0.09
13
135
210
2195
0.95
0.28
4.2
3.8
1.0
1.0
kg/l
0.08
17
289
13
161
0.81
0.27
1.1
1.1
—
—
—
0
0
299
2890
1.05
0.26
4.1
3.9
7.9
9.1
mg/mmol
0.14
169
1699
31
272
1.14
0.26
2.3
1.9
6.0
5.1
iu/l
—
9
89
33
291
1.14
0.26
1.0
1.1
1.3
6.4
u/ml
—
5
44
5
73
0.68
0.26
1.0
1.1
—
—
—
0
0
11
138
0.80
0.25
1.1
1.4
—
—
—
0
0
180
1883
0.95
0.25
1.5
1.4
—
—
—
0
0
15
181
0.83
0.25
1.2
1.1
—
—
—
0
0
37
332
1.12
0.23
2.2
1.8
—
—
—
0
0
1060
10674
0.95
0.23
4.8
4.3
4.8
4.9
mmol/l
0.48
990
10000
18
153
1.18
0.22
1.1
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.0
—
0.7
—
0
12
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
5
43
1.16
0.21
4.4
1.5
—
—
—
0
0
5
43
1.16
0.21
4.4
1.5
—
—
—
0
0
5
43
1.16
0.21
4.4
1.5
—
—
—
0
0
5
43
1.16
0.21
4.4
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
19
218
0.87
0.19
2.2
2.5
16.3
126.1
ug/min
2.70
12
134
19
217
0.87
0.18
3.4
2.4
221.3
3168.9
u/l
—
7
92
15
174
0.86
0.18
1.3
1.2
3.5
5.3
u/ml
—
8
76
32
293
1.09
0.15
1.3
1.2
1.7
2.5
u/ml
—
6
30
9
78
1.15
0.15
1.1
1.6
—
—
—
0
0
11
129
0.85
0.14
1.0
1.0
—
—
—
0
0
7
89
0.79
0.14
1.0
1.1
—
—
—
0
0
22
198
1.11
0.14
1.3
1.6
—
—
—
0
0
14
122
1.15
0.13
1.1
1.3
—
—
—
0
0
14
122
1.15
0.13
1.1
1.3
—
—
—
0
0
13
113
1.15
0.13
1.1
1.6
—
—
—
0
0
16
142
1.13
0.12
3.6
2.6
4.1
4.7
u/ml
0.15
16
137
14
123
1.14
0.12
1.1
1.3
—
—
—
0
0
14
123
1.14
0.12
1.1
1.3
—
—
—
0
0
12
137
0.87
0.12
1.2
1.5
—
—
—
0
0
11
95
1.16
0.11
5.9
3.6
—
—
—
0
0
34
318
1.07
0.11
1.2
1.2
52.6
30.3
u/ml
—
5
19
32
299
1.07
0.11
1.3
1.2
2.3
5.4
u/ml
—
9
43
134
1307
1.03
0.09
3.0
3.2
19.8
21.2
%
0.55
55
445
14
126
1.11
0.09
1.1
1.4
—
—
—
0
0
14
126
1.11
0.09
1.1
1.3
—
—
—
0
0
5
60
0.83
0.08
1.2
1.4
—
—
—
0
0
5
63
0.79
0.08
1.4
1.4
—
1312.0
—
0
5
5
65
0.77
0.08
1.2
1.4
—
—
—
0
0
6
73
0.82
0.07
1.0
1.1
—
—
—
0
0
6
75
0.80
0.07
3.8
1.4
—
—
—
0
0
6
75
0.80
0.07
3.8
1.4
—
—
—
0
0
6
75
0.80
0.07
3.8
1.4
—
—
—
0
0
18
167
1.08
0.07
1.1
1.4
—
—
—
0
0
30
313
0.96
0.05
4.3
4.2
1.3
1.4
mmol/l
0.22
30
307
16
171
0.93
0.05
2.9
1.5
—
—
—
0
0
18
170
1.06
0.04
1.1
1.5
—
—
—
0
0
22
230
0.96
0.03
1.5
2.2
1.0
0.8
nmol/l
0.32
17
194
21
219
0.96
0.03
2.7
1.5
—
—
—
0
0
1081
10821
0.99
0.02
5.4
4.7
2.9
2.9
mmol/l
0.21
1011
10071
168
1670
1.01
0.01
3.1
3.4
1.8
1.5
ug/l
0.92
156
1521
23
223
1.03
0.01
1.8
1.5
—
—
—
0
0
31
303
1.02
0.01
1.8
1.7
—
—
—
0
0
69
694
0.99
0.00
1.3
1.3
218.7
225.3
u/ml
0.03
64
630
10
97
1.03
0.00
1.0
1.4
1.1
1.0
g/l
—
10
97
40
405
0.99
0.00
1.6
1.3
—
—
—
0
0
25
255
0.98
0.00
1.3
1.6
—
—
—
0
0
17
165
1.03
0.00
1.0
1.1
—
—
—
0
0
13
125
1.04
0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
0.00
2.6
2.5
150.6
136.2
nmol/l
—
5
46
0
5
0.00
0.00
0.0
1.0
—
9.6
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
23.1
—
0
5
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
36.0
—
0
5
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
8
79
1.01
0.00
1.1
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
5.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
8.4
—
0
7
5
59
0.85
0.00
1.2
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
4.9
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
8
88
0.91
0.00
2.0
1.9
13.6
20.1
nmol/l
—
8
81
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
11.3
—
0
7
Mortality – FinRegistry
↥Association
Association between endpoint AB1_GONOCOCCAL and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_GONOCOCCAL | 1.311 [0.95, 1.82] | 0.105 |
| Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 59 out of 1743 males with AB1_GONOCOCCAL died.
Mortality risk
Mortality risk for people of age
years, who have AB1_GONOCOCCAL.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.233% |
| 5 | No data | 1.354% |
| 10 | No data | 3.354% |
| 15 | No data | 6.516% |
| 20 | No data | 10.785% |
Relationships between endpoints
↥Index endpoint: AB1_GONOCOCCAL – Gonococcal infection
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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