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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_URETER_EXALLC for full statistics.

Malignant neoplasm of ureter

C3_URETER

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C66
  • Cause of death: ICD-9 189[2-3]
  • Cause of death: ICD-8 1892
  • Cancer registry: Topography ICD-O-3 C66
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

83

4. Check minimum number of events

None

83

5. Include endpoints

None

83

6. Filter based on genotype QC (FinnGen only)

83

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 83 28 55
Unadjusted period prevalence (%) 0.02 0.01 0.02
Median age at first event (years) 73.85 73.22 74.17

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
74
Matched controls
738
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C66
ICD-10 Finland
Malignant neoplasm of ureter
4518.8
82.4
64
*
8120/3-C66.9
ICD-O-3
Transitional cell carcinoma, NOS, of ureter
+∞
80.6
62
*
UKC02
NOMESCO Finland
Cystoscopy
54.5
40.7
67
110
UKB02
NOMESCO Finland
Retrograde ureteroscopy
276.6
33.8
32
*
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
97.0
31.4
33
6
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
57.9
28.7
33
10
KAC20
NOMESCO Finland
Nephroureterectomy
370.0
26.5
25
*
D41.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Ureter
370.0
26.5
25
*
R31
ICD-10 Finland
Unspecified haematuria
16.4
24.3
46
67
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
46.6
19.4
23
7
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
34.6
18.8
24
10
KCD02
NOMESCO Finland
Transurethral resection of bladder
25.9
18.7
26
15
KAC21
NOMESCO Finland
Percutaneous endoscopic nephroureterectomy
100.3
15.2
16
*
KCD05
NOMESCO Finland
Excision of bladder lesion during urinary tract endoscopy with photodynamic diagnosis (PDD)
35.8
15.2
19
7
TPH07
NOMESCO Finland
Cathetrisation of artery
9.5
12.4
27
42
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
11.5
10.6
20
23
D41.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bladder
24.2
10.3
14
7
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
10.5
10.2
20
25
C65
ICD-10 Finland
Malignant neoplasm of renal pelvis
114.0
9.7
10
*
KH1BT
NOMESCO Finland
Urinary tract cathetrisation with X-ray guidance
114.0
9.7
10
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
11.9
9.4
17
18
KBD00
NOMESCO Finland
Partial excision of ureter
+∞
8.5
8
*
UKA02
NOMESCO Finland
Retrograde ureteronephroscopy
+∞
8.5
8
*
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
25.4
8.3
11
5
UKC05
NOMESCO Finland
Cystoscopy and bladder biopsy
25.4
8.3
11
5
KH1AD
NOMESCO Finland
CT of urinary organs
17.6
8.0
12
8
130
Kela drug reimbursment
Malignant tumour
6.6
7.9
21
42
C67.2
ICD-10 Finland
Malignant neoplasm: Lateral wall of bladder
50.5
7.9
9
*
KBH20
NOMESCO Finland
Replantation of ureter
+∞
7.4
7
*
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
11.0
7.1
13
14
WX408
NOMESCO Finland
General anesthesy, balanced
4.3
7.1
31
107
WX402
NOMESCO Finland
General anaesthesia
5.6
7.0
21
49
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.8
6.8
24
67
B01AB05
ATC
enoxaparin; parenteral
3.8
6.7
36
147
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.4
6.1
23
68

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
52
31
43.23
68.62
5.9
2.9
—
—
—
0
0
48
220
3.80
8.31
6.5
3.3
—
—
—
0
0
17
38
5.37
7.58
11.4
7.5
—
—
—
0
0
37
150
3.65
7.58
6.0
2.9
3.5
4.4
e6/l
0.44
32
134
36
146
3.59
7.33
5.6
3.2
466.0
544.7
mosm/kgh2o
1.93
30
125
43
199
3.41
7.05
7.7
3.3
0.3
0.3
e6/l
0.03
36
149
46
222
3.40
7.04
8.5
3.4
562.1
339.4
e6/l
0.19
40
174
40
187
3.20
6.30
7.6
3.2
—
—
—
0
0
48
250
3.18
6.27
9.3
4.1
154.3
63.7
e6/l
0.77
42
186
46
240
3.06
5.89
3.2
2.3
—
—
—
0
0
65
430
3.36
5.18
8.4
4.8
—
—
—
0
0
22
82
3.29
4.90
2.0
1.3
—
—
—
0
0
39
201
2.77
4.89
3.1
2.2
—
—
—
0
0
40
213
2.69
4.66
6.3
4.5
—
—
—
0
0
18
61
3.49
4.62
10.6
7.1
—
—
—
0
0
25
107
2.91
4.37
5.6
2.6
0.8
0.8
mmol/l
0.33
25
95
8
10
8.70
4.16
6.2
4.1
—
—
—
0
0
22
94
2.82
3.82
9.8
5.4
-2.1
1.3
mmol/l
2.13
16
79
48
299
2.44
3.81
17.5
9.2
1.3
1.4
inr
0.16
15
86
37
211
2.36
3.52
6.3
4.4
7.4
7.4
ph
—
8
46
52
354
2.26
3.14
10.2
5.5
9.4
11.8
umol/l
2.14
52
329
13
51
2.84
2.59
4.3
3.6
—
—
—
0
0
49
350
1.98
2.34
12.7
9.0
4.2
4.3
e9/l
0.11
39
301
70
573
2.42
2.27
28.7
17.4
48.7
28.4
mg/l
3.06
64
478
5
9
5.83
2.24
1.2
1.7
—
—
—
0
0
35
227
1.94
2.18
5.3
3.5
2.3
2.3
mmol/l
0.00
30
193
43
301
1.89
2.12
8.0
6.2
0.0
0.0
estimate
—
9
59
7
20
3.72
2.10
5.6
3.7
—
—
—
0
0
43
304
1.86
2.03
6.1
4.6
0.0
0.0
estimate
—
10
56
24
140
2.00
2.00
3.4
3.2
2.5
2.5
mmol/l
0.01
17
124
43
305
1.85
2.00
6.0
4.6
0.0
0.0
estimate
—
10
62
69
580
2.12
1.80
27.7
16.5
—
—
—
0
0
13
62
2.30
1.76
1.8
1.3
—
—
—
0
0
5
13
4.02
1.74
2.2
2.5
—
—
—
0
0
34
238
1.73
1.57
5.3
4.5
—
—
—
0
0
31
212
1.74
1.55
4.7
4.9
—
—
—
0
0
6
21
3.00
1.53
4.8
2.0
23.7
24.4
mmol/l
—
6
14
38
278
1.68
1.47
4.7
5.5
2.5
2.6
%
0.09
33
258
12
60
2.17
1.46
7.4
2.0
436.2
405.9
nmol/l
0.19
12
54
40
297
1.67
1.46
4.8
5.2
0.7
0.6
e9/l
0.42
31
253
5
16
3.25
1.46
5.2
2.0
—
—
—
0
0
18
106
1.89
1.44
1.8
1.8
30.9
29.5
s
0.54
18
101
40
298
1.66
1.44
4.7
5.2
0.0
0.0
e9/l
0.08
33
256
57
467
1.70
1.41
31.1
19.5
34.7
38.6
%
2.06
32
288
13
70
2.02
1.33
3.5
2.7
5.5
10.2
umol/l
1.19
13
61
40
303
1.62
1.32
4.8
5.3
1.6
1.7
e9/l
0.22
31
266
40
308
1.58
1.21
4.8
5.5
0.2
0.2
e9/l
0.35
32
266
70
619
1.84
1.18
42.9
25.3
248.3
231.8
e9/l
0.94
65
602
0
36
0.00
1.17
0.0
1.2
—
—
—
0
0
70
620
1.82
1.16
43.0
25.4
4.2
4.4
e12/l
2.17
65
601
70
620
1.82
1.16
43.0
25.3
7.3
6.8
e9/l
1.28
65
599
9
47
2.02
1.06
7.8
3.5
0.2
0.1
e6/l
—
9
47
19
125
1.67
1.06
2.3
2.4
10.4
12.6
umol/l
0.62
19
107
9
48
1.98
1.04
1.6
1.4
—
—
—
0
0
24
170
1.58
1.00
7.0
4.2
—
—
—
0
0
0
28
0.00
1.00
0.0
1.2
—
—
—
0
0
9
51
1.86
0.98
1.6
1.4
—
—
—
0
0
10
56
1.89
0.92
4.3
3.4
—
—
—
0
0
11
66
1.77
0.83
2.8
3.9
—
—
—
0
0
6
33
1.88
0.81
1.7
2.8
0.6
0.7
%
—
6
33
6
33
1.88
0.81
1.7
2.8
0.7
0.9
%
—
6
33
9
53
1.78
0.79
9.4
4.2
—
—
—
0
0
14
93
1.61
0.75
1.3
3.1
1.7
1.8
%
0.20
14
80
11
165
0.62
0.72
4.3
3.9
—
—
—
0
0
34
277
1.39
0.69
1.8
2.2
95.9
92.0
pmol/l
0.15
15
130
23
175
1.43
0.68
7.5
4.7
0.0
0.0
estimate
—
7
56
6
101
0.56
0.67
3.0
1.3
—
—
—
0
0
66
603
1.46
0.65
42.1
20.7
117.2
86.2
umol/l
3.23
66
603
19
142
1.44
0.61
4.7
4.4
—
—
—
0
0
25
198
1.38
0.59
3.1
4.0
5.5
7.7
mg/mmol
0.40
20
125
6
35
1.77
0.59
2.7
2.4
—
—
—
0
0
18
136
1.41
0.55
1.4
1.3
—
—
—
0
0
23
182
1.36
0.54
2.0
3.1
6.7
7.4
mmol/l
0.44
18
147
6
39
1.58
0.54
3.3
2.6
15.2
9.8
g/l
—
6
32
15
110
1.44
0.53
2.5
2.6
2.1
2.3
g/l
0.46
15
98
32
268
1.32
0.52
20.9
11.2
0.0
0.0
e9/l
0.71
21
223
10
67
1.56
0.52
3.3
2.9
—
—
—
0
0
48
427
1.29
0.50
4.8
4.5
—
—
—
0
0
23
185
1.34
0.49
2.0
3.1
24.1
407.4
mg/l
0.57
16
117
7
48
1.50
0.48
6.3
4.6
23.3
24.4
mmol/l
—
7
48
10
69
1.51
0.47
1.3
1.7
—
—
—
0
0
17
134
1.34
0.41
7.1
5.3
1.0
1.0
kg/l
—
6
18
0
17
0.00
0.41
0.0
1.2
—
0.2
—
0
17
0
18
0.00
0.40
0.0
1.3
—
1.2
—
0
18
5
35
1.46
0.40
5.6
2.7
17.8
121.5
u/ml
—
5
27
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
25
211
1.26
0.37
3.9
5.2
—
—
—
0
0
6
41
1.50
0.37
1.0
1.2
—
—
—
0
0
14
109
1.34
0.36
6.0
5.7
—
—
—
0
0
21
177
1.25
0.31
2.1
3.1
373.5
9848.6
umol/l
1.26
15
139
5
39
1.30
0.23
1.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
9.3
—
0
12
0
12
0.00
0.21
0.0
2.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
3.5
—
76.2
—
0
12
52
548
0.86
0.21
4.1
4.9
4.3
4.4
mmol/l
0.27
45
493
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
20
176
1.18
0.20
2.2
3.1
0.7
0.8
ug/l
0.21
13
124
52
546
0.87
0.19
4.1
4.9
1.3
1.4
mmol/l
0.55
45
482
7
61
1.16
0.18
4.0
2.2
—
—
—
0
0
8
68
1.20
0.17
1.5
1.3
—
—
—
0
0
54
564
0.88
0.17
4.8
5.5
2.4
2.5
mmol/l
0.61
48
501
54
517
1.13
0.15
5.8
4.9
1.9
2.0
mu/l
0.32
49
448
17
152
1.15
0.13
9.3
7.6
—
—
—
0
0
5
47
1.07
0.09
2.8
2.9
—
—
—
0
0
7
63
1.12
0.08
1.6
1.4
—
—
—
0
0
20
187
1.09
0.07
1.5
2.1
334.1
294.5
u/l
0.06
20
179
52
531
0.94
0.04
3.7
4.3
1.3
1.2
mmol/l
0.89
45
466
14
131
1.08
0.04
1.5
1.7
1.8
1.5
mg/l
—
9
98
56
551
1.05
0.03
5.5
5.4
6.1
6.2
mmol/l
0.21
49
491
53
538
0.96
0.02
7.4
6.6
41.8
41.6
mmol/mol
0.07
48
492
10
93
1.09
0.02
2.1
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
4.8
—
57.2
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
6
60
1.00
0.00
1.2
1.5
—
264.6
—
0
13
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
4.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
3.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
18.9
—
0
6

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_URETER – Malignant neoplasm of ureter

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).