No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
242 |
4. Check minimum number of eventsNone |
242 |
5. Include endpointsNone |
242 |
6. Filter based on genotype QC (FinnGen only) |
231 |
Control definitions (FinnGen only)
- Control exclude
- AB1_OTHER_BACTERIAL
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Whooping cough
based on the number of shared cases.
Similar with more cases:
- Whooping cough
- Other bacterial diseases
- Other bacterial diseases
- Certain infectious and parasitic diseases
- Certain infectious and parasitic diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3514 | 1889 | 1610 |
| Only index persons | 2916 | 1595 | 1321 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.05 | 0.04 |
| Only index persons | 0.05 | 0.06 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 2.90 | 3.61 | 1.74 |
| Only index persons | 4.07 | 5.08 | 2.85 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 231 | 160 | 71 |
| Unadjusted period prevalence (%) | 0.05 | 0.06 | 0.03 |
| Median age at first event (years) | 11.71 | 11.24 | 12.76 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 242
- Matched controls
- 2420
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A37.0
ICD-10 Finland
Whooping cough due to Bordetella pertussis
+∞
82.0
74
*
A37.9
ICD-10 Finland
Whooping cough, unspecified
916.0
72.0
67
*
03397
ICD-8 Finland
Whooping cough, Suspecta
+∞
23.3
22
*
03300
ICD-8 Finland
Whooping cough, Bordetalla Pertussis
+∞
20.1
19
*
R05
ICD-10 Finland
Cough
3.4
15.8
74
278
0330A
ICD-9 Finland
Whooping cough, Bordetella pertussis [B. pertussis][PERTUSSIS CAUSA BORDETELLA PERTUSSIS,EI ROKOTETULLA]
+∞
15.8
15
*
J45.9
ICD-10 Finland
Asthma, unspecified
3.2
12.7
60
224
03399
ICD-8 Finland
Whooping cough, Other and unspecified
+∞
12.6
12
*
0330B
ICD-9 Finland
Whooping cough, Bordetella pertussis [B. pertussis][PERTUSSIS CAUSA BORDETELLA PERTUSSIS,ROKOTETULLA]
+∞
12.6
12
*
R03AC02
ATC
salbutamol; inhalant
2.7
12.0
163
1045
A49.9
ICD-10 Finland
Bacterial infection, unspecified
49.3
12.0
14
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.7
11.9
94
464
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.8
9.8
58
244
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.7
9.7
63
278
R03BC03
ATC
nedocromil; inhalant
4.0
9.2
27
73
R03BA05
ATC
fluticasone; inhalant
2.6
8.7
60
271
J01FA10
ATC
azithromycin; systemic
2.4
8.6
178
1292
J01FA06
ATC
roxithromycin; oral
2.3
8.4
94
529
H02AB06
ATC
prednisolone; systemic
2.2
8.3
106
629
J45
ICD-10 Finland
Asthma
3.3
7.8
32
108
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.7
7.7
48
205
R03AC12
ATC
salmeterol; inhalant
7.1
7.7
18
27
A46
ICD-10 Finland
Erysipelas
6.3
7.6
19
32
103
Kela drug reimbursment
Diabetes, insulin-treated
2.6
7.5
49
215
J45.1
ICD-10 Finland
Nonallergic asthma
3.8
7.5
24
69
SPAT1262
SPAT
Handing over of treatment supplies
2.8
7.3
39
154
R06AE07
ATC
cetirizine; oral
2.1
7.2
122
796
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.9
7.0
35
133
H02AB04
ATC
methylprednisolone; systemic
2.9
6.8
35
135
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.8
6.7
35
136
46599
ICD-8 Finland
Acute upper respiratory infection of multiple or unspecified sites
5.6
6.6
18
34
38100
ICD-8 Finland
Otitis media without mention of mastoiditis, Acute
6.5
6.6
16
26
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.7
6.5
38
157
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
5.5
6.5
18
35
7862A
ICD-9 Finland
Symptoms involving respiratory system and other chest symptoms, Cough
71.7
6.5
7
*
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.9
6.5
33
127
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.9
6.4
15
23
0339A
ICD-9 Finland
Whooping cough, unspecified organism[PERTUSSIS NUD, EI ROKOTETULLA]
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
79
387
2.55
9.84
2.3
1.8
1.19
1.06
mg/l
0.14
58
283
47
188
2.86
8.63
1.8
1.8
—
—
—
0
0
92
535
2.16
7.37
9.5
7.3
1.08
1.09
inr
0.04
25
179
148
1068
1.99
6.25
11.1
7.4
4.08
3.90
e9/l
0.45
129
932
24
78
3.31
6.23
6.2
2.9
0.31
1.01
mmol/l
0.48
16
51
134
940
1.95
6.08
6.3
3.5
6.92
6.27
mmol/l
1.85
122
819
87
527
2.02
6.04
1.9
1.7
101.79
97.37
pmol/l
0.32
48
274
42
191
2.45
5.90
1.5
1.5
1349.60
1108.57
nmol/l
0.67
31
151
33
138
2.61
5.50
1.5
1.7
—
—
—
0
0
33
138
2.61
5.50
1.5
1.7
—
—
—
0
0
36
159
2.49
5.37
5.7
2.0
21.82
24.41
%
0.68
29
136
38
174
2.40
5.25
5.1
1.9
2.40
2.50
g/l
0.30
33
156
30
123
2.64
5.20
16.0
5.6
104.00
104.67
mmol/l
0.27
30
123
10
13
7.97
4.90
1.0
2.0
—
—
—
0
0
61
348
2.01
4.89
4.7
3.9
9.82
10.65
mg/mmol
0.05
44
222
79
496
1.88
4.76
4.9
2.6
2.34
2.36
mmol/l
0.70
70
441
102
702
1.78
4.52
3.0
2.3
71.87
74.22
nmol/l
0.34
92
645
10
16
6.47
4.34
1.0
1.9
—
—
—
0
0
99
682
1.76
4.33
12.0
5.1
1.21
1.22
mmol/l
0.70
84
593
11
21
5.43
4.19
1.1
1.8
—
—
—
0
0
61
366
1.89
4.17
2.4
2.3
7219.39
4221.11
umol/l
0.17
56
338
60
363
1.87
3.98
3.5
1.7
—
—
—
0
0
8
11
7.48
3.89
1.0
2.1
—
—
—
0
0
87
594
1.73
3.84
1.3
1.4
0.74
1.32
u/ml
1.18
23
149
73
475
1.77
3.81
2.8
2.0
46.54
56.19
u/l
3.24
67
436
72
467
1.77
3.80
2.5
2.5
79.03
21.01
ng/l
0.43
32
220
37
193
2.08
3.74
1.6
2.4
8.43
6.48
umol/l
0.27
25
157
14
45
3.24
3.71
7.3
3.7
46.91
50.99
%
0.21
14
45
22
92
2.53
3.68
1.8
1.4
—
—
—
0
0
127
967
1.66
3.68
4.0
2.7
109.65
67.29
ug/l
1.89
116
906
10
22
4.69
3.47
1.1
1.7
—
—
—
0
0
79
539
1.69
3.44
5.0
2.7
—
—
—
0
0
13
42
3.21
3.42
2.6
1.9
—
—
—
0
0
7
10
7.17
3.38
1.0
2.1
—
—
—
0
0
13
43
3.14
3.30
2.1
1.4
—
—
—
0
0
8
15
5.47
3.22
1.3
1.0
—
1.00
—
0
5
17
68
2.61
3.11
1.1
1.1
—
—
—
0
0
14
51
2.85
3.04
8.6
2.9
0.61
0.66
%
0.20
14
51
17
69
2.57
3.03
1.4
1.3
—
—
—
0
0
62
409
1.69
3.02
2.0
2.1
2.71
2.59
mg/l
0.18
45
352
10
26
3.97
3.01
14.1
2.7
24.38
24.52
mmol/l
—
10
26
5
5
10.17
2.99
1.0
1.0
—
—
—
0
0
85
611
1.60
2.95
11.7
4.4
1.21
1.22
mmol/l
0.63
78
565
109
835
1.56
2.86
3.5
2.2
—
—
—
0
0
11
33
3.44
2.85
1.3
1.1
—
—
—
0
0
7
14
5.11
2.75
1.0
1.6
—
—
—
0
0
7
14
5.11
2.75
1.0
1.6
—
—
—
0
0
18
80
2.35
2.68
1.8
1.5
—
—
—
0
0
7
15
4.77
2.61
1.1
1.7
—
—
—
0
0
5
7
7.26
2.56
1.0
2.1
—
—
—
0
0
59
403
1.61
2.48
2.0
1.9
162.02
326.72
u/l
0.50
52
387
6
12
5.10
2.41
1.2
1.9
—
—
—
0
0
11
39
2.91
2.37
7.1
3.5
53.55
55.41
%
0.23
11
39
11
39
2.91
2.37
6.6
3.5
3.65
3.71
e9/l
0.06
11
39
177
1542
1.55
2.36
5.8
4.1
40.57
37.60
mmol/mol
2.59
167
1454
174
1511
1.54
2.35
4.6
3.9
14.32
14.51
pmol/l
0.53
165
1388
41
259
1.70
2.32
1.7
1.5
395.64
29004780.10
pmol/l
0.50
36
231
17
79
2.24
2.31
4.5
3.7
5.51
2.94
ug/l
0.63
11
63
8
24
3.41
2.20
1.3
1.2
—
—
—
0
0
8
24
3.41
2.20
1.3
1.2
—
—
—
0
0
25
138
1.91
2.19
2.0
1.8
—
—
—
0
0
14
61
2.37
2.19
2.2
1.6
—
—
—
0
0
222
2059
1.95
2.19
11.7
7.3
25.90
26.21
u/l
0.08
217
1987
9
30
3.08
2.17
3.1
2.1
131.44
131.00
g/l
—
9
23
22
117
1.97
2.14
4.4
2.3
—
—
—
0
0
41
266
1.65
2.10
4.1
2.2
1.60
0.87
e6/l
0.36
21
143
15
69
2.25
2.09
1.2
1.1
2.66
5.30
u/ml
—
9
44
6
15
4.07
2.05
1.3
1.7
—
—
—
0
0
12
51
2.42
1.98
1.8
1.3
—
—
—
0
0
39
255
1.63
1.95
4.2
2.5
6.04
3.22
e6/l
0.49
19
132
7
22
3.24
1.89
1.3
1.4
—
—
—
0
0
7
22
3.24
1.89
1.4
1.1
—
—
—
0
0
61
447
1.49
1.85
4.7
2.4
0.14
0.23
e6/l
0.70
46
324
5
12
4.23
1.83
1.0
1.9
—
—
—
0
0
197
1795
1.52
1.78
5.5
4.4
1.68
1.76
mu/l
0.40
188
1677
112
925
1.39
1.76
7.1
4.3
0.00
0.00
estimate
0.50
23
202
6
18
3.39
1.75
2.8
2.3
17.17
16.26
%
—
6
9
113
936
1.39
1.74
5.0
3.1
0.14
0.00
estimate
0.48
22
193
8
30
2.72
1.74
1.5
1.6
—
—
—
0
0
189
1715
1.47
1.67
15.8
7.4
92.85
94.89
ml/min/173m2
0.51
162
1359
139
1197
1.38
1.67
6.5
3.7
485.80
67.53
e6/l
—
5
15
10
41
2.50
1.66
2.9
1.9
—
—
—
0
0
10
42
2.44
1.64
1.1
1.1
—
—
—
0
0
15
78
1.98
1.58
8.8
2.6
0.07
0.16
e6/l
0.45
15
73
17
93
1.89
1.56
18.8
4.2
25.01
24.61
mmol/l
0.28
17
93
19
108
1.82
1.56
12.8
3.7
179.11
66.25
ng/l
1.25
19
99
5
15
3.38
1.53
3.2
2.1
105.60
107.20
mmol/l
—
5
15
111
932
1.35
1.52
5.0
3.0
0.00
0.00
estimate
-0.00
21
211
29
188
1.62
1.51
1.3
1.3
114.09
132.27
iu/ml
0.10
11
73
45
323
1.48
1.51
1.4
1.4
21.00
21.13
nmol/l
0.02
38
288
212
1981
1.57
1.50
19.2
8.5
19.22
18.95
mg/l
0.05
184
1426
10
45
2.27
1.48
1.0
1.2
—
—
—
0
0
187
1708
1.42
1.47
3.8
3.2
5.89
5.58
mmol/l
2.35
179
1565
13
66
2.02
1.46
2.4
1.9
2.96
6.63
iu/l
—
5
23
37
257
1.52
1.45
3.1
3.1
2047.54
766.42
ng/l
0.58
31
197
6
22
2.77
1.44
2.3
1.4
0.92
0.79
ug/l
—
6
22
153
1361
1.34
1.37
5.4
3.5
11.43
8.19
mm/h
1.76
145
1252
5
18
2.81
1.29
1.4
1.4
—
—
—
0
0
57
441
1.38
1.28
1.6
1.6
1.43
1.36
mmol/l
0.26
48
386
15
85
1.82
1.26
1.2
1.5
—
—
—
0
0
6
26
2.34
1.19
7.8
2.3
—
—
—
0
0
13
72
1.85
1.17
3.1
2.4
106.31
96.79
%
0.80
13
72
36
263
1.43
1.12
3.3
3.0
91.86
150.16
ng/l
0.32
21
157
29
203
1.49
1.12
2.3
2.4
4742.85
4769.72
u/l
0.00
11
93
5
21
2.41
1.09
2.0
2.5
—
—
—
0
0
9
46
1.99
1.05
25.8
8.0
0.90
1.09
%
—
9
46
9
46
1.99
1.05
25.9
8.0
0.81
0.64
%
—
9
46
7
34
2.09
1.03
1.0
3.3
8.63
10.54
g/l
—
7
34
7
36
1.97
0.98
1.0
3.3
2.96
3.45
g/l
—
7
36
7
36
1.97
0.98
1.0
3.3
—
—
—
0
0
7
36
1.97
0.98
1.0
3.3
6.33
7.04
g/l
—
7
36
11
62
1.81
0.96
1.4
1.2
—
—
—
0
0
11
63
1.78
0.91
1.4
1.2
—
—
—
0
0
8
43
1.89
0.88
1.1
1.5
346.63
49.78
pmol/l
—
8
43
6
30
2.02
0.87
1.0
3.5
0.00
0.00
g/l
—
6
30
6
30
2.02
0.87
1.0
3.5
0.00
0.00
g/l
—
6
30
6
32
1.90
0.82
1.0
3.4
39.18
40.07
g/l
—
6
32
6
32
1.90
0.82
1.0
3.5
0.00
0.00
g/l
—
6
32
6
33
1.84
0.79
1.0
3.5
3.10
2.77
g/l
—
6
33
17
243
0.68
0.79
1.2
1.4
—
—
—
0
0
83
722
1.23
0.77
5.1
3.0
—
—
—
0
0
187
1766
1.26
0.76
3.9
3.8
—
—
—
0
0
43
348
1.29
0.73
1.4
1.2
8.76
31.46
iu/ml
—
8
119
7
39
1.82
0.73
1.0
1.0
—
—
—
0
0
5
25
2.02
0.73
3.2
2.1
—
—
—
0
0
187
1773
1.24
0.69
4.1
3.4
4.65
4.71
mmol/l
0.34
179
1679
13
86
1.54
0.67
18.5
6.5
110.31
126.01
g/l
1.52
13
81
57
486
1.23
0.63
5.3
3.3
0.00
0.01
estimate
0.80
22
202
185
1759
1.22
0.62
4.1
3.3
1.35
1.48
mmol/l
4.51
176
1663
8
51
1.59
0.61
1.3
1.3
—
19.50
—
0
5
10
65
1.56
0.56
1.3
1.5
33.70
34.05
nmol/l
—
10
65
6
37
1.64
0.56
2.0
1.6
6.07
6.80
mmol/l
—
6
37
11
74
1.51
0.54
2.0
2.0
37.73
38.79
u/l
0.08
11
67
232
2274
1.49
0.54
27.2
12.8
40.06
40.72
%
0.99
221
2165
6
39
1.55
0.53
1.2
1.1
—
—
—
0
0
12
83
1.47
0.53
1.3
1.5
—
—
—
0
0
11
75
1.49
0.51
1.3
1.3
—
—
—
0
0
186
1786
1.18
0.47
4.5
3.6
2.83
2.82
mmol/l
0.08
178
1678
18
138
1.33
0.47
5.4
4.5
—
—
—
0
0
177
1694
1.17
0.46
3.8
3.0
1.37
1.23
mmol/l
2.05
165
1597
25
306
0.80
0.46
1.7
1.8
—
—
—
0
0
5
31
1.63
0.43
1.6
1.2
—
—
—
0
0
52
458
1.17
0.42
1.6
1.5
—
—
—
0
0
5
35
1.44
0.39
1.0
1.7
—
—
—
0
0
11
147
0.74
0.38
1.5
1.6
—
—
—
0
0
6
41
1.47
0.36
1.5
1.0
17.00
2.94
e6/l
—
6
31
6
41
1.47
0.36
1.8
1.2
8.67
60.03
e6/l
—
6
33
33
381
0.85
0.35
2.3
1.9
—
—
—
0
0
38
337
1.15
0.29
1.3
1.2
1.56
7.29
u/ml
2.57
15
143
20
168
1.21
0.28
1.1
1.0
—
—
—
0
0
14
171
0.81
0.27
1.7
1.5
—
—
—
0
0
8
67
1.20
0.26
5.0
2.1
—
—
—
0
0
5
73
0.68
0.26
1.2
1.3
—
—
—
0
0
13
159
0.81
0.25
2.5
2.3
0.40
0.72
ug/l
—
7
79
74
693
1.10
0.24
2.0
1.7
—
—
—
0
0
16
134
1.21
0.23
1.4
1.7
—
—
—
0
0
23
200
1.17
0.23
1.8
1.4
—
—
—
0
0
5
40
1.26
0.22
1.6
1.1
3.44
3.75
mmol/l
—
5
40
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
185
1815
1.08
0.17
23.9
10.8
13.83
14.02
%
0.31
178
1792
13
113
1.16
0.13
2.2
2.2
—
—
—
0
0
17
154
1.11
0.10
1.8
1.3
—
—
—
0
0
14
126
1.12
0.09
1.0
1.3
—
22.57
—
0
7
11
97
1.14
0.09
2.2
1.3
—
—
—
0
0
6
57
1.05
0.08
1.8
5.4
23.48
24.45
mmol/l
—
6
52
15
139
1.08
0.05
1.9
2.4
—
14.29
—
0
11
11
116
0.95
0.01
1.5
1.5
—
—
—
0
0
15
152
0.99
0.00
1.7
1.5
—
—
—
0
0
15
152
0.99
0.00
1.7
1.5
—
—
—
0
0
15
152
0.99
0.00
1.7
1.4
—
—
—
0
0
15
152
0.99
0.00
1.7
1.4
—
—
—
0
0
20
202
0.99
0.00
3.4
3.1
23.34
22.14
%
—
5
69
30
299
1.00
0.00
1.6
1.5
—
—
—
0
0
61
608
1.00
0.00
2.5
2.4
—
—
—
0
0
56
555
1.01
0.00
2.2
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
200.00
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
64
0.94
-0.00
1.2
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.0
—
188.43
—
0
7
0
7
0.00
-0.00
0.0
1.3
—
9.61
—
0
7
0
9
0.00
-0.00
0.0
4.1
—
22.30
—
0
9
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.7
—
86.83
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
-0.00
1.8
1.6
—
0.00
—
0
10
0
8
0.00
-0.00
0.0
3.3
—
106.53
—
0
8
Mortality – FinRegistry
↥Association
Association between endpoint AB1_WHOOPCOUGH and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have AB1_WHOOPCOUGH.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: AB1_WHOOPCOUGH – Whooping cough
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data