Crohn's disease of large intestine

CHRONLARGE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K50.1
  • Cause of death: ICD-10 K50.1

2 out of 7 registries used, show all original rules.

2116

4. Check minimum number of events

None

2116

5. Include endpoints

None

2116

6. Filter based on genotype QC (FinnGen only)

2116

Control definitions (FinnGen only)

Control exclude
K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K50
Name in latin
Colitis regionalis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11142 5575 5526
Only index persons 10570 5321 5249
Unadjusted period prevalence (%)
Whole population 0.16 0.16 0.15
Only index persons 0.20 0.20 0.20
Median age at first event (years)
Whole population 40.90 41.88 39.80
Only index persons 40.05 41.07 39.01

-FinnGen-

Key figures

All Female Male
Number of individuals 2116 1198 918
Unadjusted period prevalence (%) 0.41 0.41 0.40
Median age at first event (years) 42.37 41.07 44.07

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1940
Matched controls
19400
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L04AX01
ATC
azathioprine; systemic
200.3
323.0
1251
175
K50.9
ICD-10 Finland
Crohn disease, unspecified
16384.0
323.0
1077
*
K50.1
ICD-10 Finland
Crohn disease of large intestine
4503599627370496.0
323.0
1939
*
K50.0
ICD-10 Finland
Crohn disease of small intestine
6762.7
323.0
832
*
K51.5
ICD-10 Finland
Left sided colitis
2656.3
323.0
546
*
A07EA02
ATC
hydrocortisone; rectal
172.0
323.0
419
31
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
+∞
323.0
403
*
A07EA06
ATC
budesonide; oral, local oral
377.1
323.0
900
44
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
1461.2
323.0
672
7
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
+∞
323.0
303
*
UJF30
NOMESCO Finland
Ileoscopy through colon
27.9
323.0
976
680
K50.8
ICD-10 Finland
Other Crohn disease
+∞
323.0
1202
*
H02AB06
ATC
prednisolone; systemic
9.4
323.0
1541
5657
A07EC02
ATC
mesalazine; oral, rectal
1408.4
323.0
1598
64
K51.8
ICD-10 Finland
Other ulcerative colitis
+∞
323.0
344
*
UJF32
NOMESCO Finland
Coloscopy
38.6
323.0
1599
2099
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
323.0
1748
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
6.7
300.9
1021
2762
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
6.5
294.3
1028
2866
L01BB02
ATC
mercaptopurine; oral
247.1
273.9
276
13
P01AB01
ATC
metronidazole; oral, rectal
5.4
258.4
1257
4939
L04AB04
ATC
adalimumab; parenteral
37.0
257.2
333
108
H02AB07
ATC
prednisone; oral
7.8
248.8
662
1209
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
2455.6
241.7
229
*
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
52.0
236.8
285
64
A07EC01
ATC
sulfasalazine; oral, rectal
10.0
236.6
519
684
K50
ICD-10 Finland
Crohn disease [regional enteritis]
2380.5
235.2
223
*
J01MA02
ATC
ciprofloxacin; systemic
4.9
231.0
1151
4434
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
+∞
217.9
205
*
UJF92
NOMESCO Finland
Capsular endoscopy
30.8
216.9
294
112
ZX120
NOMESCO Finland
Intravenous
9.0
216.8
504
724
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
10.5
213.9
451
544
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
128.4
213.4
227
20
D94
ICPC
Chronic enteritis/ulcerative colitis
219.2
157.5
161
8
C10AC01
ATC
colestyramine; oral
20.3
153.0
235
131
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
538.8
152.9
150
*
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
+∞
152.1
144
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.4
137.5
1019
4751
4AA12
NOMESCO Finland
NA
711.4
136.4
133
*
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
6.1
132.7
402
797
4AB02
NOMESCO Finland
NA
281.0
129.8
131
5
JF1BD
NOMESCO Finland
Very extensive small bowel CT
84.5
126.2
141
18
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
1242.9
121.2
117
*
TPH04
NOMESCO Finland
Cathetrisation of vein
3.8
116.0
606
2072
JN3BD
NOMESCO Finland
Extensive abdominal CT
5.3
114.6
388
867
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
40.6
111.0
140
37
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
54.3
110.6
132
26
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
10.1
107.8
225
249
WX002
NOMESCO Finland
Sedation and analgesia
3.7
103.1
552
1897
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
340.3
97.9
98
*
K51
ICD-10 Finland
Ulcerative colitis
996.8
97.9
95
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.8
97.3
903
4548
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
14.2
97.1
170
130
56300
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Regional enteritis
+∞
95.6
91
*
L04AC05
ATC
ustekinumab; parenteral
99.8
95.0
104
11
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
6.5
92.9
259
448
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
55.4
92.6
110
21
5552A
ICD-9 Finland
Regional enteritis, Small intestine with large intestine
+∞
92.4
88
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.5
89.9
513
1828
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
160.8
87.9
92
6
JFB20
NOMESCO Finland
Ileocaecal resection
66.5
87.5
101
16
K60.3
ICD-10 Finland
Anal fistula
12.9
87.2
159
133
5551A
ICD-9 Finland
Regional enteritis, Large intestine
+∞
87.1
83
*
JH1CG
NOMESCO Finland
Extensive MRI of perianal area
83.3
84.9
95
12
A02BC02
ATC
pantoprazole; systemic
2.6
81.1
1317
8775
JHA00
NOMESCO Finland
Anal or perianal incision
16.4
78.0
128
83
5550A
ICD-9 Finland
Regional enteritis, Small intestine
+∞
75.5
72
*
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
16.8
75.1
122
77
JFB00
NOMESCO Finland
Partial resection of small intestine
17.3
74.0
119
73
B03BA03
ATC
hydroxocobalamin; parenteral
6.4
72.9
203
347
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.4
72.1
284
721
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
7.4
71.4
178
260
JFA58
NOMESCO Finland
Endoscopic dilatation of colon
149.4
68.4
72
5
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.5
68.1
363
1198
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
+∞
66.0
63
*
K83.0
ICD-10 Finland
Cholangitis
21.2
65.0
97
48
N02AX02
ATC
tramadol; systemic, rectal
2.3
64.3
872
5044
M07.4
ICD-10 Finland
Arthropathy in Crohn disease [regional enteritis]
638.2
63.2
62
*
1370
FHL
Colonoscopy, whole colon
59.1
63.1
74
13
A07DA03
ATC
loperamide; oral
8.2
63.0
146
190
A07EA01
ATC
prednisolone; rectal
165.3
61.3
64
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
60.7
631
3167
UJF02
NOMESCO Finland
Peroral enteroscopy
50.5
60.6
73
15
A06AC01
ATC
ispaghula (psylla seeds); oral
2.7
60.5
508
2261
WX302
NOMESCO Finland
Thoracal epidural anesthesy
5.5
60.2
189
373
K61.0
ICD-10 Finland
Anal abscess
10.1
59.6
122
128
JF1AD
NOMESCO Finland
Small bowel CT
54.1
57.2
68
13
Z93.2
ICD-10 Finland
Ileostomy status
65.0
54.6
63
10
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
+∞
54.4
52
*
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
53.4
51
*
JX1LA
NOMESCO Finland
Kinetic X-ray of alimentary tract with pictures
273.0
52.4
53
*
A05AA02
ATC
ursodeoxycholic acid; oral
11.2
52.2
101
95
J01MA12
ATC
levofloxacin; systemic
2.7
51.9
402
1687
107
Kela drug reimbursment
Pernicious anaemia
12.4
51.3
94
79
Z01.8
ICD-10 Finland
Other specified special examinations
2.5
51.2
490
2315
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.1
50.5
319
1169
A02BC01
ATC
omeprazole; systemic
2.3
50.5
568
2915
5568X
ICD-9 Finland
Idiopathic proctocolitis, Other ulcerative colitis
+∞
49.2
47
*
R50.9
ICD-10 Finland
Fever, unspecified
2.8
48.2
352
1418
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.2
47.2
190
485
A02BC03
ATC
lansoprazole; oral
2.2
47.0
583
3116
A07EC03
ATC
olsalazine; oral
468.5
46.5
46
*
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
13.6
45.6
80
61
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
13.0
45.2
81
65
JFB33
NOMESCO Finland
Other resection comprising small intestine and colon
123.0
44.9
48
*
H02AB09
ATC
hydrocortisone; systemic
7.2
44.8
112
163
3AC01
NOMESCO Finland
NA
14.4
43.9
75
54
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.0
43.8
276
1006
N02BE01
ATC
paracetamol; systemic, rectal
2.3
43.2
1637
13614
4AA33
NOMESCO Finland
NA
+∞
42.9
41
*
JN3AD
NOMESCO Finland
Abdominal CT examination
3.8
42.5
196
563
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.4
42.1
219
694
3042
Kela drug reimbursment
NA
+∞
41.8
40
*
JFA38
NOMESCO Finland
Endoscopic dilatation of small intestine
416.0
41.3
41
*
253
Kela drug reimbursment
NA
+∞
40.8
39
*
K56.7
ICD-10 Finland
Ileus, unspecified
12.4
40.0
73
61
M45
ICD-10 Finland
Ankylosing spondylitis
7.0
39.2
100
150
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
48.1
38.9
47
10
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
4.9
38.5
131
281
B81
ICPC
Anaemia vit B12/folate deficiency
5.8
38.1
112
203
JFB30
NOMESCO Finland
Right hemicolectomy
16.0
38.0
62
40
5559X
ICD-9 Finland
Regional enteritis, Unspecified site
+∞
37.6
36
*
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
374.2
37.1
37
*
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
8.6
37.0
82
99
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.0
36.7
155
412
5561A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis
+∞
35.5
34
*
JHD30
NOMESCO Finland
Incomplete incision of fistula-in-ano
27.3
35.1
48
18
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.1
35.1
213
750
6403
FHL
Ileocal resection
353.3
35.0
35
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.9
34.8
735
4742
WVA20
NOMESCO Finland
Medicine administration
7.9
34.6
81
107
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
33.7
825
5584
JFG40
NOMESCO Finland
Revision of enterostomy or colostomy without laparotomy
41.8
33.1
41
10
JF1CM
NOMESCO Finland
Small bowel extensive MRI with with high intensity magnet
332.5
33.0
33
*
M05BA04
ATC
alendronic acid; oral
3.8
32.7
146
407
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
322.1
31.9
32
*
JHD33
NOMESCO Finland
Completing incision of fistula-in-ano
34.9
31.9
41
12
UJD02
NOMESCO Finland
Gastroscopy
4.3
31.5
122
299
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
30.9
425
2308
JF1DM
NOMESCO Finland
Very extensive MRI of small bowel (more than 1.5 T)
162.5
30.8
32
*
JFH10
NOMESCO Finland
Total colectomy and ileostomy
111.8
30.7
33
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.2
30.7
359
1816
JHD20
NOMESCO Finland
Incision of fistula-in-ano
9.3
30.5
64
71
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
4.2
30.2
119
296
D64.9
ICD-10 Finland
Anaemia, unspecified
3.1
30.1
175
595
J01DB01
ATC
cefalexin; oral
1.9
30.0
1587
13542
WX402
NOMESCO Finland
General anaesthesia
2.2
29.8
363
1866
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
5.9
29.8
85
149
A07AA09
ATC
vancomycin; oral
11.8
29.7
55
48
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
11.1
28.3
54
50
K92.1
ICD-10 Finland
Melaena
4.1
28.2
113
286
Z93
ICD-10 Finland
Artificial opening status
55.9
28.2
33
6
A02BA02
ATC
ranitidine; systemic
2.1
27.7
343
1770
H02AB04
ATC
methylprednisolone; systemic
2.3
27.7
294
1417
JAH00
NOMESCO Finland
Laparotomy
5.3
27.3
85
166
XJW99
NOMESCO Finland
Other investigative procedure on digestive system
26.9
27.1
37
14
UJH02
NOMESCO Finland
Anoscopy
3.9
26.9
113
299
B01AB05
ATC
enoxaparin; parenteral
1.9
26.7
500
3033
L04AD01
ATC
ciclosporin; systemic
6.3
26.6
72
118
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
5.8
26.6
77
138
C05AA08
ATC
fluocortolone; rectal, topical
2.2
26.3
286
1392
TJF80
NOMESCO Finland
Ostomy education
12.6
26.3
47
38
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.3
26.3
139
443
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
5.3
25.7
80
156
UJG02
NOMESCO Finland
Proctoscopy
6.1
25.4
70
118
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
25.3
854
6197
JHW96
NOMESCO Finland
Other operation on anus or perianal tissue
22.9
25.2
36
16
L04AA01
ATC
[U] ciclosporin; systemic
7.4
25.1
60
83
L04AA33
ATC
vedolizumab; parenteral
+∞
25.0
24
*
D07AC01
ATC
betamethasone; topical
1.8
25.0
614
4055
JFF13
NOMESCO Finland
Terminal enterostomy
39.4
24.9
31
8
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
5.3
24.8
77
150
JH1CM
NOMESCO Finland
Perianal extensive MRI with 3 Tesla magnet
91.3
24.7
27
*
A03CA02
ATC
clidinium and psycholeptics; oral
3.5
24.7
122
370
UJK12
NOMESCO Finland
Peroral cholangioscopy
131.7
24.6
26
*
E0000UV
ATC
NA
1.7
24.3
741
5208
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.5
24.2
202
858
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.7
24.1
628
4210
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
5.9
23.8
67
116
A02BC05
ATC
esomeprazole; systemic
1.7
23.6
711
4969
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
4.7
23.1
80
176
M09.1*K50.9
ICD-10 Finland
Juvenile arthritis in Crohn's disease [regional enteritis]
+∞
23.0
22
*
JFB21
NOMESCO Finland
Laparoscopic ileocaecal resection
40.6
22.7
28
7
JFG50
NOMESCO Finland
Laparotomy with revision of enterostomy or colostomy
121.4
22.6
24
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.3
22.5
218
1000
WX110
NOMESCO Finland
Local anesthesy
1.6
22.1
1318
10957
JFH11
NOMESCO Finland
Laparoscopic colectomy
+∞
21.9
21
*
UJF34
NOMESCO Finland
Left colonoscopy
13.4
21.5
37
28
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
11.3
21.4
40
36
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
8.7
20.9
45
53
6455
FHL
Perianal fistula surgery
18.0
20.9
32
18
5586X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis[KROONINEN INFLAMMATOORINEN SUOLISTOSAIRAUS, NUD]
+∞
20.9
20
*
4AC05
NOMESCO Finland
NA
+∞
20.9
20
*
56399
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Other
+∞
20.9
20
*
K65.0
ICD-10 Finland
Acute peritonitis
9.3
20.3
42
46
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
5.7
20.3
59
107
B01AB10
ATC
tinzaparin; parenteral
2.8
20.3
136
510
ZX112
NOMESCO Finland
Subcutaneous
5.4
20.2
61
116
1490
FHL
Sigmoideoscopy (fiberscope)
48.5
20.2
24
5
6402
FHL
Small bowel resection
48.5
20.2
24
5
0093A
ICD-9 Finland
Ill-defined intestinal infections, Diarrhoea of presumed infectious origin
7.8
20.1
46
60
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
6.7
20.0
51
78
JFF10
NOMESCO Finland
Loop enterostomy
19.0
20.0
30
16
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
10.2
19.9
39
39
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.8
19.7
85
231
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.7
19.6
137
527
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
7.7
19.4
45
60
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.1
19.3
247
1280
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
6.9
19.3
48
71
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.7
19.3
135
520
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.7
19.1
139
546
WW200
NOMESCO Finland
Immunization
3.8
18.9
81
219
K29.3
ICD-10 Finland
Chronic superficial gastritis
4.1
18.9
74
185
JGB50
NOMESCO Finland
Mucosal proctectomy and ileoanal anastomosis
+∞
18.8
18
*
Z94.4
ICD-10 Finland
Liver transplant status
21.0
18.6
27
13
6404
FHL
Hemicolectomy on the right
101.0
18.6
20
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.2
18.4
195
930
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.5
18.3
146
606
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.4
18.3
167
741
TPH07
NOMESCO Finland
Cathetrisation of artery
2.3
18.2
175
797
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.1
18.1
207
1023
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.4
17.8
87
263
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
23.0
17.7
25
11
5560A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) enterocolitis
+∞
17.7
17
*
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.5
17.6
141
586
L01BB01
ATC
NA
37.1
17.6
22
6
E000001
ATC
NA
1.7
17.4
382
2393
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
11.2
17.2
32
29
S18
ICPC
Laceration/cut
1.6
17.2
680
4993
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.3
17.2
158
706
K61.1
ICD-10 Finland
Rectal abscess
14.9
17.1
28
19
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
4.2
17.1
66
163
K63.1
ICD-10 Finland
Perforation of intestine (nontraumatic)
11.6
17.0
31
27
A07AA02
ATC
nystatin; oral
2.8
16.9
109
400
K63.2
ICD-10 Finland
Fistula of intestine
90.8
16.6
18
*
RD210
NOMESCO Finland
NA
4.9
16.5
54
113
K59.1
ICD-10 Finland
Functional diarrhoea
3.0
16.5
97
335
UJK02
NOMESCO Finland
ERCP
4.8
16.4
55
118
J05AB11
ATC
valaciclovir; oral
1.9
16.4
243
1329
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.1
16.4
90
297
D07AB02
ATC
hydrocortisone butyrate; topical
1.6
16.3
489
3344
K91.4
ICD-10 Finland
Colostomy and enterostomy malfunction
30.3
16.1
21
7
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.8
16.1
104
382
L88
ICD-10 Finland
Pyoderma gangrenosum
24.7
16.0
22
9
D07AC13
ATC
mometasone; topical
1.6
15.9
495
3408
A06AC51
ATC
ispaghula, combinations; systemic
2.8
15.7
101
370
J02AC01
ATC
fluconazole; systemic
1.5
15.7
710
5348
JFH33
NOMESCO Finland
Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy
+∞
15.6
15
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
15.6
330
2039
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
26.5
15.6
21
8
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
15.3
193
994
JFA70
NOMESCO Finland
Suture of small intestine
28.8
15.2
20
7
K60.4
ICD-10 Finland
Rectal fistula
23.6
15.1
21
9
R11
ICD-10 Finland
Nausea and vomiting
2.3
15.0
149
690
Z93.3
ICD-10 Finland
Colostomy status
8.2
15.0
33
41
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.6
15.0
538
3830
JHD00
NOMESCO Finland
Anal dilatation
9.5
14.9
30
32
WW500
NOMESCO Finland
Blood transfusion
3.1
14.8
80
262
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.8
14.7
96
356
C10AC02
ATC
colestipol; oral
25.2
14.7
20
8
ZJX00
NOMESCO Finland
Double balloon technique in gastroenterological endoscopy
25.2
14.7
20
8
B04AD01
ATC
NA
25.2
14.7
20
8
N03AX16
ATC
pregabalin; oral
1.7
14.6
377
2463
JFA60
NOMESCO Finland
Stricturoplasty in small intestine
+∞
14.6
14
*
D99
ICPC
Disease digestive system other
7.3
14.5
34
47
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
5.0
14.5
46
94
B02.9
ICD-10 Finland
Zoster without complication
2.8
14.5
93
340
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
14.5
676
5101
127
Kela drug reimbursment
Transplant complication
4.8
14.4
48
103
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
14.4
392
2598
J01DA01
ATC
[U] cefalexin; systemic
1.5
14.4
1121
9395
K56.0
ICD-10 Finland
Paralytic ileus
9.2
14.2
29
32
K91.2
ICD-10 Finland
Postsurgical malabsorption, not elsewhere classified
42.8
14.1
17
*
M13.9
ICD-10 Finland
Arthritis, unspecified
2.3
14.1
130
583
K29.7
ICD-10 Finland
Gastritis, unspecified
3.5
14.0
66
195
JFB43
NOMESCO Finland
Left hemicolectomy
10.1
14.0
27
27
SPAT1255
SPAT
Intravenous administration of medicine
2.5
13.9
114
480
N02AA05
ATC
oxycodone; systemic
2.0
13.8
190
1009
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.0
13.8
188
995
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.3
13.7
125
557
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
3.3
13.7
69
215
JFB96
NOMESCO Finland
Other partial excision of intestine
75.7
13.6
15
*
K76.9
ICD-10 Finland
Liver disease, unspecified
5.0
13.6
43
88
JGB40
NOMESCO Finland
Excision of rectum and end ileostomy
+∞
13.6
13
*
D50.8
ICD-10 Finland
Other iron deficiency anaemias
5.4
13.3
39
73
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
2.7
13.1
89
338
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
13.1
850
6822
D01
ICPC
Abdominal pain/cramps general
1.9
13.1
194
1062
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
4.0
13.1
51
129
B07.9
ICD-10 Finland
Verruca simplex
2.9
13.0
77
269
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.0
13.0
166
860
6454
FHL
Incision of perianal abscess
28.6
13.0
17
6
S97
ICPC
Chronic ulcer skin
2.8
12.9
81
294
S10
ICPC
Boil/carbuncle
2.4
12.9
109
469
J01FF01
ATC
clindamycin; systemic
1.5
12.9
469
3330
1380
FHL
Colonoscopy, left side
50.3
12.8
15
*
L04AB06
ATC
golimumab; parenteral
6.3
12.7
33
53
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.2
12.7
65
205
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.8
12.7
227
1324
M01AH01
ATC
celecoxib; oral (coxibs)
1.7
12.7
281
1752
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
12.7
289
1820
B03BA02
ATC
cyanocobalamin tannin complex; parenteral
12.3
12.6
22
18
JFB46
NOMESCO Finland
Resection of sigmoid colon
6.2
12.6
33
54
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.9
12.6
77
273
K55.9
ICD-10 Finland
Vascular disorder of intestine, unspecified
32.2
12.6
16
5
TQW99
NOMESCO Finland
Other minor procedure on skin
2.9
12.5
77
274
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.5
12.5
96
390
M07.5
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
12.5
12
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.3
12.4
61
187
A01AB09
ATC
miconazole; local oral
2.1
12.4
151
766
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.4
12.3
107
465
5660A
ICD-9 Finland
Abscess of anal and rectal regions[ABSCESSUS ANI ET ANORECTALIS]
14.4
12.3
20
14
JAH01
NOMESCO Finland
Laparoscopy
2.6
12.2
89
353
WX610
NOMESCO Finland
Patient controlled analgesia
6.4
12.1
31
49
5651A
ICD-9 Finland
Anal fissure and fistula, Anal fistula[FISTULA ANI]
12.5
12.1
21
17
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
12.0
238
1434
K02.1
ICD-10 Finland
Caries of dentine
1.4
12.0
1070
9054
6419
FHL
Other measure in this category
46.9
11.9
14
*
1470
FHL
Rectoscopy
8.4
11.8
25
30
M81.4
ICD-10 Finland
Drug-induced osteoporosis
10.6
11.8
22
21
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
10.6
11.8
22
21
K29.8
ICD-10 Finland
Duodenitis
6.7
11.7
29
44
UKC02
NOMESCO Finland
Cystoscopy
1.8
11.7
212
1244
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
3.1
11.7
64
213
N11.9
ICD-10 Finland
Chronic tubulo-interstitial nephritis, unspecified
12.6
11.6
20
16
JJC00
NOMESCO Finland
Allogenic transplantation of liver
19.0
11.6
17
9
D07XC01
ATC
betamethasone, combinations; topical
1.8
11.5
198
1140
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.3
11.5
56
171
E86
ICD-10 Finland
Volume depletion
4.2
11.5
43
105
6408
FHL
Colectomy and ileostomy
+∞
11.5
11
*
K51.4
ICD-10 Finland
Inflammatory polyps
120.7
11.4
12
*
SPAT1262
SPAT
Handing over of treatment supplies
1.7
11.3
267
1693
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
7.0
11.3
27
39
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
11.9
11.3
20
17
JFH00
NOMESCO Finland
Total colectomy and ileorectal anastomosis
15.1
11.3
18
12
5604
FHL
Vascular preparation or cannulation in the operating room
35.2
11.3
14
*
D07AD01
ATC
clobetasol; topical
1.7
11.3
249
1551
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.0
11.2
150
790
71240
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Spondylitis ankylopoietica
20.1
11.1
16
8
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
11.1
702
5555
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
5.1
11.1
34
68
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.7
11.0
74
281
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
11.0
576
4398
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.2
11.0
107
495
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.4
10.9
1052
8946
K60.1
ICD-10 Finland
Chronic anal fissure
3.3
10.9
53
162
R10.0
ICD-10 Finland
Acute abdomen
2.9
10.9
64
224
WX892
NOMESCO Finland
Monitored bed care
2.1
10.8
120
586
A04.9
ICD-10 Finland
Bacterial intestinal infection, unspecified
7.2
10.7
25
35
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
3.6
10.7
47
133
L04AA06
ATC
mycophenolic acid; systemic
3.7
10.7
45
123
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
3.5
10.7
49
144
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.0
10.6
59
199
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.4
10.6
93
405
KH1AD
NOMESCO Finland
CT of urinary organs
2.9
10.6
62
216
WZC30
NOMESCO Finland
Teaching
1.8
10.6
204
1219
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
4.7
10.6
35
76
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
3.4
10.6
49
145
A41.9
ICD-10 Finland
Sepsis, unspecified
3.1
10.5
55
178
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
5.1
10.5
32
64
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.2
10.5
38
91
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
10.4
976
8235
JF1CD
NOMESCO Finland
Extensive small bowel CT
+∞
10.4
10
*
JFG73
NOMESCO Finland
Excision of ileal pelvic pouch
+∞
10.4
10
*
M09.2*K51.9
ICD-10 Finland
Juvenile arthritis in ulcerative colitis
+∞
10.4
10
*
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
10.4
207
1247
B99
ICD-10 Finland
Other and unspecified infectious diseases
4.2
10.3
38
92
JGB96
NOMESCO Finland
Other proctectomy or excision of rectum
32.7
10.3
13
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.1
10.3
118
584
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.3
10.3
89
389
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.7
10.3
206
1248
N11.8
ICD-10 Finland
Other chronic tubulo-interstitial nephritis
18.9
10.3
15
8
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
4.5
10.2
35
79
D07AB08
ATC
desonide; topical
1.8
10.2
176
1018
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
3.5
10.1
46
134
F43.29
ICD-10 Finland
Adaptation disorder UNS
3.3
10.1
49
150
QBA10
NOMESCO Finland
Incision of skin of trunk
4.7
10.1
33
71
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
10.1
367
2590
J01MA14
ATC
moxifloxacin; systemic
1.9
10.1
140
750
C05AA01
ATC
hydrocortisone; rectal, topical
2.4
10.0
84
360
JHA20
NOMESCO Finland
Excision of lesion of anal canal or perianal tissue
5.0
10.0
31
63
SPAT1125
SPAT
Stoma care and guidance
6.5
10.0
25
39
L52
ICD-10 Finland
Erythema nodosum
6.5
10.0
25
39
JF2AB
NOMESCO Finland
Colongraphy with X-ray
14.6
10.0
16
11
JFA96
NOMESCO Finland
Other local operation on intestine
40.3
10.0
12
*
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
2.7
10.0
67
255
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
9.9
306
2077
D11
ICPC
Diarrhoea
1.7
9.9
204
1245
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
9.9
263
1721
7200A
ICD-9 Finland
Ankylosing spondylitis and other inflammatory spondylopathies, Ankylosing spondylitis
12.2
9.8
17
14
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
8.2
9.8
21
26
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.9
9.8
155
869
D95
ICPC
Anal fissure/perianal abscess
5.4
9.8
28
52
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
9.8
1204
10574
N82.3
ICD-10 Finland
Fistula of vagina to large intestine
20.1
9.8
14
7
K63.0
ICD-10 Finland
Abscess of intestine
20.1
9.8
14
7
JGB30
NOMESCO Finland
Abdominoperineal excision of rectum
10.7
9.8
18
17
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.4
9.8
963
8158
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
9.6
9.8
19
20
A02BX02
ATC
sucralfate; oral
2.8
9.7
61
222
R03AC02
ATC
salbutamol; inhalant
1.4
9.7
902
7567
K52.80
ICD-10 Finland
(Hemorrhagic) colitis caused by antibiotics
55.3
9.6
11
*
M25.5
ICD-10 Finland
Pain in joint
1.4
9.6
464
3468
D06BX01
ATC
metronidazole; topical
1.8
9.6
171
996
K85
ICD-10 Finland
Acute pancreatitis
3.9
9.6
38
99
E87.6
ICD-10 Finland
Hypokalaemia
3.5
9.5
43
126
L20.0
ICD-10 Finland
Besnier prurigo
1.9
9.5
131
701
K30
ICD-10 Finland
Functional dyspepsia
1.8
9.4
166
966
6525
FHL
Enterostomy occlusion
+∞
9.4
9
*
5589X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis, Other and unspecified non-infectious gastro-enteritis and colitis
+∞
9.4
9
*
JN2DM
NOMESCO Finland
Lower part of abdomen very extensive MRI examination with Tesla magnet
12.4
9.4
16
13
QBE15
NOMESCO Finland
Excision of other superficial lesion of skin of trunk
8.7
9.3
19
22
NA6AA
NOMESCO Finland
Sacro-iliac joint X-ray examination
10.7
9.3
17
16
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.7
9.3
214
1346
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
4.5
9.3
31
69
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.4
9.2
76
324
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
2.4
9.2
76
324
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
9.2
148
833
A02BA03
ATC
famotidine; systemic
2.7
9.2
59
219
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.8
9.2
153
871
ULA02
NOMESCO Finland
Kolposcopy
1.8
9.2
160
926
K45.8
ICD-10 Finland
Other specified abdominal hernia without obstruction or gangrene
7.8
9.1
20
26
T81.9
ICD-10 Finland
Unspecified complication of procedure
3.8
9.1
37
99
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
11.5
9.1
16
14
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
4.7
9.0
29
62
56510
ICD-8 Finland
Anal fissure and fistula, Anal fistula
15.6
9.0
14
9
JWF00
NOMESCO Finland
Reoperation for insufficiency of anastomosis or suture in gastroenterological surgery
15.6
9.0
14
9
M01AH02
ATC
rofecoxib; oral
1.7
9.0
176
1055
Z43.2
ICD-10 Finland
Attention to ileostomy
36.9
9.0
11
*
K90.8
ICD-10 Finland
Other intestinal malabsorption
36.9
9.0
11
*
K60.5
ICD-10 Finland
Anorectal fistula
36.9
9.0
11
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
9.0
271
1828
Y0599
ICD-8 Finland
Investigation of digestive system
4.0
8.9
34
86
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
1.8
8.9
158
921
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.4
8.8
70
292
JWA00
NOMESCO Finland
Repair of wound dehiscence in gastroenterological surgery
8.6
8.8
18
21
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
2.5
8.8
68
283
J01FA10
ATC
azithromycin; systemic
1.3
8.7
1058
9184
Z94.0
ICD-10 Finland
Kidney transplant status
4.2
8.7
31
74
JAD10
NOMESCO Finland
Repair of incisional hernia
6.6
8.7
21
32
EBA00
NOMESCO Finland
Extraction of tooth
1.4
8.6
557
4376
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.1
8.6
45
148
M01AE01
ATC
ibuprofen; systemic, rectal
0.7
8.5
1475
15843
A06AD11
ATC
lactulose; oral
1.7
8.5
171
1035
K52.2
ICD-10 Finland
Allergic and dietetic gastroenteritis and colitis
27.6
8.5
11
*
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
27.6
8.5
11
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
8.5
156
921
E000002
ATC
NA
1.7
8.5
195
1226
K29.9
ICD-10 Finland
Gastroduodenitis, unspecified
6.0
8.4
22
37
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
2.8
8.4
53
195
JA3BT
NOMESCO Finland
Cathetrisation of abdominal cavity with X-ray guidance
12.8
8.4
14
11
N32.1
ICD-10 Finland
Vesicointestinal fistula
12.8
8.4
14
11
XQ800
NOMESCO Finland
Prick test
1.8
8.3
135
762
N05CF01
ATC
zopiclone; oral
1.4
8.3
448
3405
56902
ICD-8 Finland
Other diseases of intestines and peritoneum, Proctitis haemorrhagica (ulcerosa)
+∞
8.3
8
*
6406
FHL
Other column resection
+∞
8.3
8
*
4AA17
NOMESCO Finland
NA
+∞
8.3
8
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.0
8.3
104
536
K83.1
ICD-10 Finland
Obstruction of bile duct
5.3
8.3
24
46
L40.8
ICD-10 Finland
Other psoriasis
5.3
8.3
24
46
AA1AD
NOMESCO Finland
CT of head and brain
1.5
8.3
304
2143
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
4.6
8.3
27
59
JFB50
NOMESCO Finland
Other resection of colon
10.8
8.3
15
14
K60.2
ICD-10 Finland
Anal fissure, unspecified
3.3
8.3
40
124
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
4.2
8.3
30
73
RS221
NOMESCO Finland
NA
3.9
8.2
32
83
SPAT1325
SPAT
Vaccination
1.4
8.2
492
3813
R4190
NOMESCO Finland
Nutritional therapy
2.4
8.2
69
296
R06AE07
ATC
cetirizine; oral
1.3
8.2
765
6367
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
2.1
8.2
87
419
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
3.5
8.2
36
104
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
5.7
8.1
22
39
L73.8
ICD-10 Finland
Other specified follicular disorders
4.7
8.1
26
56
H22.1*M45
ICD-10 Finland
Iridocyclitis in ankylosing spondylitis
17.2
8.1
12
7
5BA08
NOMESCO Finland
NA
8.9
8.0
16
18
R4110
NOMESCO Finland
Physiotherapy
1.4
7.9
395
2956
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.1
7.9
88
433
N20.1
ICD-10 Finland
Calculus of ureter
2.5
7.9
59
241
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
3.0
7.9
42
140
K62.4
ICD-10 Finland
Stenosis of anus and rectum
13.1
7.9
13
10
SPAT1153
SPAT
Removal of sutures
1.4
7.8
458
3532
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
3.4
7.8
35
103
UJF30
SPAT
NA
7.0
7.8
18
26
K74.3
ICD-10 Finland
Primary biliary cirrhosis
7.0
7.8
18
26
N05BA04
ATC
oxazepam; oral
1.4
7.7
381
2844
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
3.1
7.7
40
131
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.5
7.7
58
238
JFB01
NOMESCO Finland
Laparoscopic partial resection of small intestine
45.1
7.7
9
*
SPAT1263
SPAT
Sampling
1.3
7.7
694
5729
R01AD12
ATC
fluticasone furoate; nasal
1.4
7.6
518
4093
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
3.0
7.6
40
133
D06BB10
ATC
imiquimod; topical
2.1
7.6
78
372
L82
ICD-10 Finland
Seborrhoeic keratosis
1.6
7.5
203
1333
Z01.2
ICD-10 Finland
Dental examination
1.3
7.5
715
5945
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
2.2
7.4
70
321
J01AA02
ATC
doxycycline; systemic
1.3
7.4
1307
11843
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
13.4
7.4
12
9
L40.9
ICD-10 Finland
Psoriasis, unspecified
3.6
7.4
31
87
L30.3
ICD-10 Finland
Infective dermatitis
2.4
7.3
59
252
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
4.4
7.3
25
58
J01FA06
ATC
roxithromycin; oral
1.3
7.3
641
5262
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
7.3
1279
11559
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
7.3
644
5291
56398
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Alia definita
+∞
7.3
7
*
4AB04
NOMESCO Finland
NA
+∞
7.3
7
*
5761C
ICD-9 Finland
Other disorders of biliary tract, Cholangitis[CHOLANGITIS SCLEROSIVA]
+∞
7.3
7
*
5563A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctosigmoiditis
+∞
7.3
7
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
3.5
7.3
32
93
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.6
7.3
174
1106
1310
FHL
Esophagogastroscopy
9.4
7.3
14
15
KBE12
NOMESCO Finland
Transluminal endoscopic extraction of calculus of ureter
4.9
7.3
22
45
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.9
7.2
109
602
JFF11
NOMESCO Finland
Laparoscopic loop enterostomy
15.8
7.2
11
7
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.4
7.2
437
3383
TQW80
NOMESCO Finland
Local dermatologic skincare
2.7
7.2
47
179
A03FA02
ATC
cisapride; oral, rectal
1.9
7.2
103
561
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
2.1
7.2
73
347
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.4
7.2
377
2849
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.2
7.2
71
335
JK3MN
NOMESCO Finland
Bile absorbtion isotope examination
30.1
7.1
9
*
D50.1
ICD-10 Finland
Sideropenic dysphagia
30.1
7.1
9
*
N06AA09
ATC
amitriptyline; systemic
1.7
7.1
137
819
D29
ICPC
Digestive symptom/complaint other
3.1
7.1
37
122
WD315
NOMESCO Finland
Multiple therapy of methastized malignancy with biomodifiers
20.1
7.1
10
5
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.1
7.1
78
384
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
5.0
7.1
21
42
K60.0
ICD-10 Finland
Acute anal fissure
4.0
7.1
26
65
NF1AA
NOMESCO Finland
Hip X-ray examination
1.9
7.0
104
573
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
7.0
222
1514
TQW11
NOMESCO Finland
Vacuum treatment of wound
3.1
6.9
36
119
SGC00
NOMESCO Finland
Local medication of root channels of tooth
1.6
6.9
186
1221
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
3.0
6.9
37
125
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
4.2
6.9
24
57
R51.80
ICD-10 Finland
Headache
1.5
6.9
239
1664
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
6.9
280
2016
WX882
NOMESCO Finland
High dependency care
2.7
6.9
45
172
-50
ICPC
Medication/prescr/renewal
2.2
6.8
63
286
GD1AD
NOMESCO Finland
Thorax CT examination
2.3
6.8
60
265
WX306
NOMESCO Finland
Lumbar epidural anesthesy
1.8
6.8
122
713
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
4.4
6.8
23
53
JN2AE
NOMESCO Finland
Ultrasound examination of lower part of abdomen without contrast
4.4
6.8
23
53
318
Kela drug reimbursment
Teriparatide
8.3
6.8
14
17
H05AA02
ATC
teriparatide; parenteral
8.3
6.8
14
17
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.6
6.8
177
1151
R06.0
ICD-10 Finland
Dyspnoea
1.4
6.8
330
2453
KAT00
NOMESCO Finland
Extracorporeal shock wave lithotripsy of pelvis of kidney
5.0
6.8
20
40
K13.00
ICD-10 Finland
Cheilitis NOS
11.0
6.8
12
11
9731
FHL
Opening and channeling of the inflammatory site in the operating room or anesthesia
11.0
6.8
12
11
N06AX11
ATC
mirtazapine; oral
1.3
6.8
488
3881
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
3.9
6.8
26
68
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.9
6.8
100
552
A01AB04
ATC
amphotericin B; local oral
2.2
6.8
65
301
K61.3
ICD-10 Finland
Ischiorectal abscess
40.2
6.8
8
*
TK800
NOMESCO Finland
Hemodialysis
2.8
6.7
40
144
M03BX02
ATC
tizanidine; oral
1.3
6.7
1071
9502
5781A
ICD-9 Finland
Gastro-intestinal haemorrhage, Melaena[MELAENA]
16.7
6.7
10
6
K63.8
ICD-10 Finland
Other specified diseases of intestine
16.7
6.7
10
6
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.0
6.7
81
412
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.0
6.7
85
440
L57.0
ICD-10 Finland
Actinic keratosis
1.9
6.7
97
528
A02BA04
ATC
nizatidine; systemic
1.9
6.7
99
544
TQW40
NOMESCO Finland
Remowal of suture of skin
1.8
6.7
110
625
J01FA09
ATC
clarithromycin; systemic
1.3
6.6
520
4186
N06AX21
ATC
duloxetine; oral
1.6
6.6
169
1094
K62.8
ICD-10 Finland
Other specified diseases of anus and rectum
5.2
6.6
19
37
M79.6
ICD-10 Finland
Pain in limb
1.3
6.6
530
4280
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
6.6
175
1144
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.8
6.6
39
140
J01MA01
ATC
ofloxacin; systemic
1.8
6.6
111
636
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
6.6
252
1788
D16
ICPC
Rectal bleeding
3.0
6.6
35
118
XF600
NOMESCO Finland
Bloodpressure measurement
1.9
6.6
90
481
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.8
6.6
39
141
JN2BD
NOMESCO Finland
Extensive CT exmaniation of lower part of abdomen
8.7
6.5
13
15
K61.2
ICD-10 Finland
Anorectal abscess
8.7
6.5
13
15
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
6.5
367
2800
SPAT1254
SPAT
Administration of medicine
1.5
6.5
195
1311
D05AX52
ATC
calcipotriol, combinations; topical
1.9
6.5
88
469
WX320
NOMESCO Finland
Spinalanesthesy
1.4
6.5
315
2341
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.8
6.5
38
135
L88
ICPC
Rheumatoid/seropositive arthritis
2.3
6.5
56
248
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
6.5
237
1667
L73.2
ICD-10 Finland
Hidradenitis suppurativa
3.6
6.5
27
76
JFF23
NOMESCO Finland
Transversostomy
4.5
6.5
21
47
K43.0
ICD-10 Finland
Incisional hernia with obstruction, without gangrene
5.3
6.5
18
34
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.8
6.5
108
619
K08.3
ICD-10 Finland
Retained dental root
1.8
6.4
99
554
JKA20
NOMESCO Finland
Cholecystectomy
2.8
6.4
38
137
B80
ICPC
Iron deficiency anaemia
3.0
6.4
34
115
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
6.4
837
7225
D07AA02
ATC
hydrocortisone; topical
1.5
6.4
223
1557
M05BA07
ATC
risedronic acid; oral
2.8
6.3
37
132
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.9
6.3
88
473
M50.8
ICD-10 Finland
Other cervical disc disorders
5.5
6.3
17
31
S85
ICPC
Pilonidal cyst/fistula
11.1
6.3
11
10
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.5
6.3
45
181
JFK00
NOMESCO Finland
Division of adhesive band in intestinal obstruction
18.1
6.3
9
5
M074, K508
ICD-10 Finland
NA
+∞
6.3
6
*
JFG96
NOMESCO Finland
Other operation on intestinal stoma or pouch
+∞
6.3
6
*
WX004
NOMESCO Finland
Patient-controlled sedation
7.0
6.2
14
20
K59.9
ICD-10 Finland
Functional intestinal disorder, unspecified
3.5
6.2
27
79
I84.5
ICD-10 Finland
External hemorrhoids without complication
2.3
6.2
51
221
M01AX17
ATC
nimesulide; oral
1.4
6.2
313
2345
A01AC01
ATC
triamcinolone; local oral
3.3
6.2
29
90
ZZR00
NOMESCO Finland
Flap of skin
3.3
6.2
29
90
N19
ICD-10 Finland
Unspecified kidney failure
2.8
6.2
37
135
TKC20
NOMESCO Finland
Catheterisation of bladder
1.9
6.2
79
415
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
5.3
6.1
17
32
D02AX
ATC
Other emollients and protectives
2.3
6.1
51
223
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
6.1
454
3617
K55.0
ICD-10 Finland
Acute vascular disorders of intestine
7.7
6.1
13
17
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
7.7
6.1
13
17
J05AB01
ATC
aciclovir; systemic
1.4
6.1
313
2351
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.6
6.1
160
1043
WZA90
NOMESCO Finland
Other doctors statement
1.4
6.0
368
2845
TPX10
NOMESCO Finland
Implantation of vascular injection port
2.4
6.0
46
191

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1716
8002
7.05
323.01
17.3
5.6
58.7
56.5
%
16.08
1673
7535
1722
8115
7.03
318.25
18.4
5.8
27.6
29.1
%
8.62
1683
7622
1840
6166
16.21
307.65
11.9
4.5
36.6
36.3
g/l
1.94
1802
5747
1846
8268
10.66
307.65
18.2
5.6
0.6
0.6
e9/l
0.73
1769
7212
1715
7764
7.38
307.65
18.2
5.8
2.6
2.8
%
3.58
1670
7265
1800
1836
59.95
307.65
8.5
1.3
211.2
86.7
ug/g
30.22
1737
1409
1846
8289
10.62
307.65
18.3
5.6
0.0
0.0
e9/l
1.47
1772
7227
1399
1455
26.42
307.65
2.3
1.2
—
—
—
0
0
1701
7508
7.45
307.65
18.2
5.8
0.7
0.7
%
7.18
1659
7047
1861
8583
10.69
307.65
18.5
5.9
0.2
0.2
e9/l
3.09
1789
7615
1716
7820
7.32
307.65
18.6
6.0
8.8
8.4
%
8.14
1674
7370
1746
6500
10.64
307.65
4.5
2.2
74.7
74.9
nmol/l
0.11
1702
5946
223
33
75.42
307.65
3.1
1.3
9.1
8.6
mg/l
0.18
194
26
1890
9547
10.17
307.65
20.0
8.8
4.0
4.0
e9/l
0.08
1818
8363
1525
5357
7.61
307.65
15.1
5.8
—
—
—
0
0
1851
8570
10.26
307.65
18.2
5.6
1.8
2.0
e9/l
3.97
1787
7626
1164
3618
5.93
307.65
4.7
2.0
2.8
2.9
mg/l
0.51
1083
3093
550
1159
6.06
259.39
6.5
4.0
0.3
0.6
%
2.12
127
252
2024
12340
15.72
247.70
22.8
6.7
75.3
76.7
u/l
0.93
1996
11643
564
1277
5.66
244.82
6.9
4.2
0.7
0.9
%
0.44
149
344
275
283
11.02
243.20
5.3
3.2
3.8
4.1
e9/l
1.40
275
283
547
1221
5.69
240.97
7.0
4.2
0.1
0.1
%
0.38
142
318
528
1147
5.80
239.60
7.0
4.3
0.0
0.7
%
0.99
128
270
276
292
10.72
239.24
5.4
3.5
58.8
56.5
%
1.90
276
292
1456
7456
4.05
200.53
20.8
8.5
0.0
0.0
e9/l
0.59
1370
6098
614
1882
4.19
177.78
3.2
2.4
21.0
24.3
%
7.11
540
1614
1857
12164
5.30
161.10
8.8
3.7
13.5
10.2
mm/h
17.60
1775
11354
923
3930
3.39
160.00
12.8
4.0
—
—
—
0
0
1383
7569
3.39
155.77
4.7
2.7
96.9
112.3
ug/l
2.99
1336
7080
614
2070
3.77
152.60
3.2
2.3
2.4
2.4
g/l
0.61
585
1916
645
2251
3.68
152.12
3.3
2.4
12.4
14.2
umol/l
7.76
630
2076
468
1344
4.19
145.66
4.4
2.3
0.2
0.2
g/l
3.28
438
1257
251
436
6.40
140.86
1.7
1.2
69.0
97.9
titre
0.99
21
42
1130
5771
3.06
137.96
2.4
1.8
92.0
97.0
pmol/l
3.27
757
3075
642
2365
3.46
137.48
1.6
1.6
—
—
—
0
0
1389
8072
3.10
132.14
8.4
6.0
10.1
11.2
umol/l
3.82
1337
7655
112
0
+∞
117.82
2.7
0.0
23.0
—
mg/l
—
107
0
343
929
4.21
113.91
1.6
1.2
—
—
—
0
0
1165
6527
2.75
111.88
2.7
1.9
—
—
—
0
0
1060
5668
2.74
111.63
5.8
3.2
31.2
31.6
u/l
0.14
980
5415
580
2301
3.09
106.42
2.1
1.7
1186.9
1176.9
nmol/l
0.06
416
1787
738
3359
2.84
105.16
1.6
1.7
—
—
—
0
0
339
970
3.97
103.91
1.9
1.8
1.2
1.4
g/l
1.24
317
896
939
4859
2.68
103.58
5.0
2.4
60.0
56.8
u/l
0.92
889
4513
840
4153
2.70
101.04
13.7
6.6
—
—
—
0
0
121
133
9.59
100.67
2.0
1.2
—
—
titre
—
0
0
390
1253
3.59
100.65
2.4
2.7
11.5
10.6
g/l
3.77
358
1148
1020
5667
2.54
94.81
9.0
7.3
1.1
1.2
inr
3.23
378
1733
1212
7313
2.54
94.08
8.5
6.5
1.2
1.2
mmol/l
0.20
1016
6241
563
2378
2.86
90.48
1.6
1.3
483.0
484.3
titre
0.01
161
470
1115
6595
2.46
88.57
7.4
5.9
1.2
1.2
mmol/l
0.03
1024
6026
109
126
9.07
87.16
1.5
1.2
157.4
186.0
titre
0.12
38
15
737
3728
2.50
80.96
5.7
4.1
—
—
—
0
0
634
3003
2.59
79.92
2.5
1.6
432.7
36235720.8
pmol/l
3.35
572
2550
503
2151
2.76
77.62
1.3
1.2
—
—
—
0
0
172
378
4.86
73.59
1.3
1.3
340.9
250.3
u/ml
2.13
106
240
774
4268
2.28
67.40
5.4
3.9
7.4
7.4
ph
1.26
165
815
2052
17408
6.91
67.02
33.8
11.4
15.8
22.1
mg/l
27.23
1892
13372
135
272
5.23
63.79
2.2
1.6
0.8
0.8
g/l
0.09
112
211
619
3183
2.34
62.83
1.7
1.5
21.2
20.7
nmol/l
0.21
553
2777
418
1798
2.65
62.49
4.9
2.9
5.7
7.7
umol/l
2.82
365
1559
212
631
3.62
60.14
1.8
1.5
5.9
20.0
u/ml
0.56
14
14
721
4014
2.21
59.92
6.8
3.8
95.3
93.4
%
1.34
706
3914
341
1378
2.76
57.32
4.8
3.5
—
—
—
0
0
737
4238
2.13
55.56
1.9
2.0
—
—
—
0
0
152
386
4.17
53.91
1.9
1.2
2.0
5.4
iu/ml
—
5
5
107
210
5.31
51.99
2.8
3.4
1.5
1.4
%
0.09
77
184
114
255
4.67
47.52
1.1
1.2
—
—
—
0
0
1482
11325
2.03
47.17
5.7
3.9
—
—
—
0
0
441
2190
2.28
46.89
2.8
2.0
—
—
—
0
0
336
1486
2.50
46.40
3.5
2.3
39.0
70.9
u/l
0.50
303
1277
616
3522
2.06
45.48
1.8
1.4
2.6
2.3
g/l
4.53
456
2213
200
682
3.13
45.34
1.4
1.3
—
—
—
0
0
177
565
3.33
44.74
1.6
1.8
—
—
—
0
0
155
462
3.54
43.61
5.0
3.5
71.1
3119.1
u/ml
0.79
136
395
2061
18508
5.37
41.13
33.8
12.9
77.8
74.2
umol/l
3.84
2061
18502
319
1454
2.41
40.93
4.0
2.9
1.9
1.8
%
1.20
291
1314
341
1603
2.34
40.79
2.4
2.1
315.9
373.5
nmol/l
6.25
313
1491
2064
18595
5.48
40.11
28.2
9.0
26.8
27.6
u/l
1.53
2052
18033
72
125
5.93
39.86
2.9
3.2
60.2
52.2
%
1.67
45
95
144
434
3.49
39.79
3.4
3.1
—
—
—
0
0
1243
9271
1.83
38.68
6.4
4.6
6.5
6.6
mmol/l
1.40
1182
8593
1116
8089
1.80
37.88
5.6
4.4
0.0
0.0
estimate
0.50
380
1505
380
1926
2.19
37.70
9.0
6.1
1.0
1.0
mmol/l
0.02
360
1809
543
3150
1.97
37.37
3.4
2.4
6.2
6.3
e6/l
0.05
498
2765
46
53
8.85
36.72
3.6
3.2
—
—
—
0
0
1773
14952
2.15
36.67
34.5
14.1
13.8
13.5
%
19.25
1768
14629
281
1268
2.40
36.66
11.0
8.1
9.0
8.5
mmol/l
0.58
272
1219
1119
8169
1.78
36.58
4.4
3.2
0.0
0.0
estimate
1.08
370
1436
1107
8072
1.78
36.18
4.4
3.2
0.0
0.0
estimate
0.50
369
1464
672
4239
1.86
35.54
4.9
3.5
0.0
0.0
estimate
0.04
371
1464
505
2933
1.95
34.23
3.6
2.6
537.7
552.3
mosm/kgh2o
0.68
458
2495
73
152
4.94
33.13
3.4
4.0
—
—
—
0
0
1057
7743
1.73
32.77
5.6
3.8
—
—
—
0
0
432
2410
2.00
32.75
5.2
3.7
0.8
0.8
mmol/l
1.88
405
2282
655
4199
1.81
32.27
4.4
2.9
0.5
0.4
e6/l
0.29
548
3113
91
231
4.07
32.20
1.1
1.1
1.6
1.5
g/l
1.10
82
208
315
1583
2.16
31.55
1.4
1.5
—
—
—
0
0
60
110
5.58
31.38
2.0
1.6
—
—
—
0
0
358
1893
2.07
31.37
2.0
1.6
—
—
—
0
0
56
97
5.90
31.07
2.2
1.5
14.1
25.2
umol/l
2.57
51
92
648
4182
1.79
30.98
4.2
2.8
—
—
—
0
0
234
1049
2.38
30.77
2.5
2.9
76.4
72.1
e9/l
0.64
178
778
698
4614
1.77
30.68
4.4
3.0
46.9
84.5
e6/l
1.04
591
3494
1340
10592
1.72
30.49
5.4
3.9
821.0
1339.6
e6/l
—
8
135
153
567
2.83
29.69
1.8
2.0
1.5
1.4
g/l
0.48
138
501
746
5074
1.73
29.35
3.4
2.2
—
—
—
0
0
1945
17415
2.45
28.61
23.7
12.8
3.9
3.9
mmol/l
12.96
1899
16928
1940
17352
2.42
28.59
23.6
12.7
139.3
139.7
mmol/l
12.30
1902
16899
120
399
3.13
28.23
1.4
1.5
—
—
—
0
0
869
6236
1.67
27.52
3.7
3.0
—
5.7
—
0
5
133
477
2.91
27.40
1.4
1.1
—
—
—
0
0
261
1293
2.16
26.89
4.7
4.3
3.1
23.2
ug/l
2.07
211
1035
133
483
2.87
26.78
4.1
4.5
1.5
1.4
mg/l
1.02
125
452
243
1177
2.20
26.48
3.2
2.8
4.3
4.1
e9/l
0.50
162
974
112
373
3.11
26.27
1.4
1.5
100.7
121.6
u/ml
0.88
21
72
719
5000
1.66
25.15
3.4
3.3
2.3
2.4
mmol/l
4.30
623
4484
118
419
2.92
24.75
1.1
1.2
—
—
—
0
0
669
4598
1.67
24.31
4.2
2.8
—
—
—
0
0
114
402
2.94
24.21
1.4
1.5
—
14.4
—
0
8
768
5526
1.61
22.93
5.0
3.4
62.7
64.3
e6/l
0.02
616
3781
197
928
2.24
22.89
4.0
3.5
5.1
5.1
kpa
0.85
184
874
253
1320
2.04
22.58
1.4
1.4
—
—
—
0
0
573
3845
1.67
22.53
3.4
2.1
—
—
—
0
0
765
5534
1.60
22.15
3.6
3.1
24.7
46.6
ng/l
1.91
482
3338
41
74
5.63
21.82
26.9
29.5
115.5
133.0
ug/l
0.55
33
60
192
921
2.19
21.31
4.0
3.5
7.4
7.4
ph
0.20
28
104
603
4156
1.63
21.11
3.4
2.7
—
—
—
0
0
245
1299
2.00
20.85
5.8
4.0
1.0
2.0
mmol/l
2.98
204
1048
127
517
2.55
20.45
1.7
1.7
0.2
0.2
g/l
0.07
120
488
161
734
2.29
20.20
6.7
4.4
23.1
24.1
mmol/l
2.83
152
679
130
539
2.50
20.15
1.7
1.7
1.2
1.2
g/l
0.18
122
508
1990
18406
2.36
20.14
23.6
10.7
—
—
—
0
0
243
1304
1.98
19.95
5.9
4.0
5.9
5.9
kpa
0.08
237
1265
232
1225
2.00
19.94
9.4
8.9
—
—
—
0
0
257
1407
1.94
19.90
4.5
3.9
—
—
—
0
0
78
248
3.23
19.80
4.4
3.8
39.3
1276.1
u/ml
0.67
71
230
86
300
2.95
18.65
3.6
3.4
—
—
—
0
0
147
670
2.28
18.44
1.3
1.2
0.6
1.1
u/ml
0.42
11
55
120
512
2.42
17.49
2.1
2.1
5.2
1.7
ug/l
0.75
111
460
138
627
2.28
17.44
1.3
1.2
—
—
—
0
0
321
1967
1.74
17.16
1.8
1.4
—
—
—
0
0
194
1021
1.99
16.77
4.8
4.2
95.4
82.4
ng/l
0.92
177
926
43
104
4.20
16.30
1.2
1.0
—
—
—
0
0
212
1162
1.92
16.26
5.4
3.5
1.2
1.2
mmol/l
1.26
187
1002
152
745
2.12
15.93
1.1
1.1
—
—
—
0
0
2075
19815
3.44
15.41
44.1
16.9
275.1
254.7
e9/l
30.12
2066
19364
142
691
2.13
15.16
4.2
3.7
—
—
—
0
0
43
111
3.93
14.96
1.2
1.0
—
—
—
0
0
2075
19837
3.38
14.94
44.0
16.9
4.4
4.6
e12/l
31.05
2060
19347
2075
19843
3.36
14.81
44.1
16.9
6.9
6.7
e9/l
4.01
2064
19357
2075
19847
3.35
14.72
44.3
17.0
134.4
137.6
g/l
21.06
2069
19617
559
4070
1.51
14.43
1.3
1.3
1.4
1.7
u/ml
0.32
134
1127
380
2546
1.60
14.23
3.7
2.5
1.1
0.9
e6/l
0.75
235
1405
80
311
2.63
14.20
1.1
1.1
—
—
—
0
0
96
408
2.42
14.15
1.5
1.4
270.6
301.0
ug/g
0.68
55
228
51
158
3.28
13.57
1.8
2.7
1.0
1.2
e9/l
0.65
26
88
36
89
4.10
13.29
1.1
1.1
1656.2
1616.0
miu/ml
0.06
36
89
18
23
7.88
13.16
2.3
1.9
—
—
—
0
0
357
2402
1.58
13.04
3.8
2.7
3.0
2.6
e6/l
0.40
214
1269
190
1079
1.84
13.01
4.1
3.4
5.1
4.7
kpa
1.02
183
1043
53
173
3.12
12.96
1.3
1.3
2.8
3.0
g/l
0.25
37
124
53
173
3.12
12.96
1.3
1.3
0.3
0.4
g/l
0.88
36
121
37
96
3.90
12.81
3.3
3.3
—
—
—
0
0
53
175
3.08
12.72
1.3
1.3
—
—
—
0
0
337
2263
1.58
12.37
2.2
2.3
29.7
29.6
s
0.18
332
2193
52
173
3.06
12.33
1.3
1.3
7.1
6.8
g/l
0.17
36
124
16
20
8.05
11.89
2.3
1.5
—
—
—
0
0
210
1271
1.72
11.57
7.2
7.6
1.3
1.4
mmol/l
0.77
201
1220
43
134
3.25
11.38
3.3
3.3
—
—
—
0
0
81
354
2.34
11.27
3.2
3.3
8.8
8.6
kpa
0.61
76
334
77
329
2.39
11.27
3.2
3.5
30.7
35.0
umol/l
1.52
69
289
70
289
2.47
11.04
2.9
2.5
16.6
16.6
%
0.01
42
140
1401
12390
1.39
11.01
5.4
3.0
54.8
43.7
u/l
3.22
1326
11765
78
340
2.34
10.93
2.7
2.9
24.0
24.7
mmol/l
0.80
69
306
153
858
1.84
10.91
1.4
2.4
—
—
—
0
0
197
1191
1.72
10.89
3.9
3.2
—
—
—
0
0
63
249
2.58
10.88
1.4
1.3
—
—
—
0
0
302
2039
1.56
10.75
1.4
1.2
—
—
—
0
0
245
1576
1.63
10.69
9.5
8.0
5.0
5.1
kpa
1.09
235
1513
244
1576
1.62
10.47
9.6
8.0
12.6
12.8
kpa
0.34
235
1516
71
303
2.39
10.44
1.1
1.1
—
—
—
0
0
75
328
2.33
10.44
4.0
3.6
2.7
2.4
mmol/l
0.30
54
212
220
1393
1.65
10.22
10.0
8.5
96.2
95.9
%
0.41
211
1349
241
1568
1.61
10.03
9.7
8.0
0.3
1.1
mmol/l
1.94
190
1229
60
242
2.52
9.97
2.9
2.6
—
—
—
0
0
496
3756
1.42
9.89
1.8
1.8
1.1
1.0
mg/l
0.33
360
2792
28
72
3.93
9.86
3.0
5.0
—
—
—
0
0
534
4128
1.39
9.38
2.9
2.5
3122.0
4302.5
umol/l
0.35
488
3656
39
131
3.01
9.17
2.0
2.7
513.1
731.4
e6/l
1.49
22
54
205
1311
1.62
9.14
10.6
8.6
117.5
123.8
g/l
4.59
197
1270
530
4112
1.39
9.07
3.6
3.3
—
—
—
0
0
63
274
2.34
8.93
2.5
2.7
8.7
6.2
umol/l
0.81
44
201
42
150
2.84
8.87
1.7
2.4
35.3
41.4
%
—
6
23
68
308
2.25
8.77
2.5
2.3
130.5
131.8
g/l
0.15
52
226
565
4450
1.37
8.76
2.2
2.1
148.3
223.8
u/l
2.27
548
4212
81
394
2.10
8.75
4.1
3.4
7.4
7.4
ph
0.12
73
323
172
1067
1.67
8.65
2.0
2.7
66.3
67.2
g/l
0.77
160
992
474
3640
1.39
8.56
4.1
3.2
—
—
—
0
0
239
1620
1.54
8.30
20.6
19.1
1.3
1.2
inr
0.21
41
243
146
880
1.71
8.18
7.8
5.0
—
—
—
0
0
36
124
2.94
8.13
1.4
2.2
12.5
13.0
%
0.06
13
63
12
17
7.09
8.00
1.2
1.1
—
—
—
0
0
454
3507
1.38
7.84
2.8
3.0
1429.9
1021.0
ng/l
1.15
389
2912
1788
16778
1.42
7.81
28.6
12.3
39.8
40.6
%
4.20
1283
13231
23
61
3.80
7.80
1.4
2.1
—
—
—
0
0
88
463
1.94
7.70
2.3
2.5
—
—
—
0
0
74
374
2.01
7.27
1.6
3.8
37.9
32.6
mg/l
0.59
57
302
338
2524
1.40
7.10
3.2
2.9
2.4
2.4
mmol/l
0.18
291
2227
72
364
2.01
7.08
1.6
3.8
1.1
3.2
ratio
—
6
35
73
374
1.99
6.92
1.6
3.8
53.5
77.8
mg/l
0.59
56
302
50
226
2.24
6.56
2.2
1.4
66.9
65.3
mmol/l
0.07
38
189
36
141
2.58
6.46
1.0
1.1
293.2
287.2
mg/l
0.15
31
128
118
720
1.68
6.37
1.9
1.8
—
—
—
0
0
55
265
2.10
6.19
6.5
2.9
—
—
—
0
0
129
814
1.62
6.12
3.8
3.2
127.7
131.7
g/l
1.12
124
795
361
2812
1.34
5.77
4.0
3.3
172.5
503.5
ng/l
3.31
239
1942
116
725
1.63
5.74
10.0
10.7
23.5
24.3
mmol/l
2.02
111
690
84
1409
0.58
5.73
1.3
1.4
—
—
—
0
0
44
202
2.20
5.61
1.3
1.3
—
—
—
0
0
32
128
2.52
5.54
1.1
1.2
—
90.3
—
0
8
79
450
1.78
5.48
1.3
1.2
2.5
2.6
u/ml
—
6
47
55
278
2.00
5.48
1.6
4.0
—
—
—
0
0
117
743
1.61
5.44
14.4
10.6
—
—
—
0
0
368
2899
1.33
5.43
1.3
1.2
6.0
11.3
u/ml
1.32
134
1177
130
851
1.56
5.32
10.3
7.3
24.1
24.5
mmol/l
0.65
121
794
18
54
3.35
5.16
1.2
1.3
—
—
—
0
0
1249
11404
1.23
5.16
3.6
3.3
—
—
—
0
0
41
191
2.17
5.08
1.5
1.6
—
—
—
0
0
41
191
2.17
5.08
1.5
1.6
—
—
—
0
0
41
191
2.17
5.08
1.5
1.6
—
—
—
0
0
41
191
2.17
5.08
1.5
1.6
—
—
—
0
0
71
402
1.79
5.05
1.3
1.4
—
—
—
0
0
12
27
4.46
5.03
1.0
1.6
11.5
1330006.4
nmol/l
—
6
20
175
1235
1.45
5.02
1.4
1.3
191.1
210.9
u/ml
0.13
164
1147
158
1098
1.47
4.91
2.2
2.2
6.2
7.7
ug/l
0.51
137
997
9
10
9.03
4.78
1.3
1.6
451.4
377.6
umol/24h
—
9
10
57
307
1.88
4.77
3.0
3.2
—
—
—
0
0
43
210
2.07
4.74
1.3
1.6
—
—
—
0
0
378
3049
1.29
4.66
1.3
1.3
16.5
29.3
iu/ml
4.20
116
931
143
986
1.48
4.63
2.8
2.8
178.4
161.7
ng/l
0.19
128
882
81
490
1.68
4.60
2.0
2.2
252.2
284.1
ug/l
0.14
72
460
130
881
1.51
4.58
2.5
2.2
4060.2
4446.2
u/l
0.05
47
357
176
2402
0.71
4.58
1.2
1.3
—
—
—
0
0
87
540
1.64
4.49
11.0
5.2
0.9
0.9
%
0.01
82
505
102
659
1.58
4.47
1.9
2.5
21.3
21.1
s
0.31
93
577
46
236
1.97
4.46
1.2
1.2
—
—
—
0
0
62
353
1.78
4.38
2.5
1.7
10342.1
12372.8
e6/l
0.34
50
261
87
545
1.62
4.34
11.0
5.2
1.6
1.6
%
0.19
82
508
49
262
1.89
4.23
1.3
1.7
—
—
—
0
0
194
1445
1.38
4.14
1.1
1.2
—
—
—
0
0
55
310
1.79
4.04
15.5
7.0
11.5
11.2
mmol/l
0.24
50
280
17
58
2.95
4.01
1.3
3.2
77.5
116.5
umol/l
0.42
11
30
55
311
1.79
4.00
15.5
7.0
106.2
105.5
mmol/l
0.53
50
281
20
75
2.68
3.99
1.1
1.0
—
—
—
0
0
493
4186
1.23
3.87
3.5
3.3
522.4
340.0
mg/l
0.36
328
2696
38
195
1.97
3.73
1.1
1.3
—
—
nmol/l
—
0
0
609
6935
0.83
3.70
2.4
2.5
—
—
—
0
0
46
253
1.84
3.68
2.4
2.4
—
—
—
0
0
49
278
1.78
3.56
2.0
1.8
—
—
—
0
0
19
74
2.58
3.55
1.1
1.1
—
—
—
0
0
557
4829
1.21
3.52
3.5
3.3
8.0
8.0
mmol/l
0.10
479
4151
47
266
1.78
3.45
2.3
1.6
—
—
—
0
0
1579
16502
0.83
3.36
3.7
3.6
1.4
1.3
mmol/l
5.59
1463
15467
81
536
1.53
3.27
3.4
3.4
0.3
0.3
g/l
0.01
37
236
49
287
1.72
3.22
1.5
1.5
—
—
—
0
0
1647
17117
0.83
3.11
3.9
3.9
1.4
1.4
mmol/l
0.42
1533
16089
68
438
1.57
3.11
13.8
6.0
1.3
1.2
mmol/l
0.29
61
385
20
86
2.34
3.08
2.0
1.6
—
—
—
0
0
27
132
2.06
3.07
2.1
1.5
34.7
33.8
%
0.04
18
83
19
80
2.39
3.06
1.2
1.1
270.9
199.9
iu/ml
0.49
19
80
80
537
1.51
3.05
4.3
4.9
—
—
—
0
0
504
4387
1.20
3.01
4.4
4.0
12.6
9.2
mg/mmol
0.61
336
2823
1651
15819
1.20
2.99
4.6
4.5
1.7
2.1
mu/l
1.83
1527
14743
588
5192
1.18
2.98
1.6
1.5
—
—
—
0
0
32
169
1.91
2.95
2.3
3.0
—
—
—
0
0
1681
17418
0.83
2.94
4.2
4.3
2.7
2.9
mmol/l
14.91
1560
16342
1411
13358
1.17
2.88
4.0
3.9
14.7
14.6
pmol/l
1.32
1294
12342
60
383
1.58
2.87
1.4
2.3
38.1
38.2
g/l
0.04
49
338
27
136
2.00
2.85
1.1
1.2
—
—
—
0
0
23
110
2.10
2.79
1.2
1.2
—
—
—
0
0
408
3509
1.20
2.76
4.5
3.4
1.0
1.0
kg/l
0.18
69
483
75
510
1.49
2.72
1.2
1.1
—
—
—
0
0
31
169
1.85
2.63
2.2
1.6
49.2
58.2
%
0.50
17
109
19
87
2.19
2.57
1.2
1.4
149.0
140.4
nmol/l
0.30
19
87
22
108
2.05
2.51
1.1
1.1
—
—
—
0
0
26
137
1.91
2.46
2.0
1.4
302574.6
89836.6
e6/l
0.35
18
92
13
51
2.56
2.44
3.5
2.2
—
—
—
0
0
6
12
5.01
2.40
1.0
1.1
—
—
—
0
0
16
71
2.26
2.34
1.1
1.1
—
—
—
0
0
19
91
2.10
2.33
1.9
2.9
2634.2
1065.9
u/ml
0.45
19
91
32
184
1.75
2.32
1.6
1.4
355.0
300.8
pmol/l
0.38
25
142
15
65
2.32
2.31
1.8
1.6
—
—
—
0
0
35
207
1.70
2.30
1.2
1.4
—
—
—
0
0
1667
17201
0.85
2.26
4.0
4.0
4.6
4.7
mmol/l
10.06
1554
16252
9
29
3.11
2.22
1.7
2.8
—
—
—
0
0
14
61
2.30
2.14
1.4
1.1
—
—
—
0
0
52
349
1.50
2.08
2.3
2.1
—
—
—
0
0
12
50
2.41
2.02
1.8
1.4
39.7
47.5
%
0.30
12
44
91
682
1.35
2.00
4.0
3.0
—
—
—
0
0
9
32
2.82
2.00
2.3
2.3
—
—
—
0
0
26
148
1.77
1.98
2.1
1.6
1.1
1.3
promille
0.23
16
119
21
112
1.88
1.96
1.1
1.2
—
—
—
0
0
5
11
4.55
1.94
1.0
1.1
—
—
—
0
0
26
150
1.74
1.91
2.5
1.5
0.9
1.0
g/l
1.16
26
150
5
12
4.17
1.82
1.0
1.1
—
—
—
0
0
89
683
1.32
1.71
1.4
1.4
8.3
8.8
u/l
0.15
75
560
0
48
0.00
1.69
0.0
1.1
—
—
—
0
0
6
19
3.16
1.66
8.7
3.1
3.5
7.4
mmol/l
—
6
19
31
196
1.59
1.66
1.1
1.7
—
—
—
0
0
24
142
1.70
1.64
3.4
2.2
—
—
—
0
0
14
69
2.04
1.64
1.3
1.2
—
—
—
0
0
126
1018
1.25
1.63
3.0
2.5
—
—
—
0
0
139
1139
1.24
1.59
1.4
1.3
49.8
51.0
au/ml
—
6
60
136
1113
1.24
1.58
1.4
1.4
—
—
—
0
0
13
248
0.52
1.57
1.2
1.2
—
—
—
0
0
11
50
2.21
1.57
1.3
1.7
—
—
—
0
0
63
467
1.36
1.54
1.8
2.1
11.2
10.6
mg/l
0.18
56
433
13
64
2.04
1.54
1.2
1.8
—
—
—
0
0
66
494
1.35
1.52
1.4
1.3
—
—
—
0
0
21
123
1.71
1.51
1.0
1.1
—
—
—
0
0
1596
16399
0.89
1.50
4.0
4.0
5.8
5.8
mmol/l
0.38
1465
15224
52
377
1.39
1.47
1.1
1.6
—
—
—
0
0
89
1122
0.78
1.46
1.1
1.2
—
—
—
0
0
23
140
1.65
1.45
1.2
1.1
—
—
—
0
0
148
1235
1.21
1.45
2.6
2.3
15.5
22.5
au/ml
0.30
11
85
15
80
1.88
1.44
1.2
1.2
—
—
—
0
0
39
552
0.70
1.41
1.4
1.5
—
—
—
0
0
38
538
0.70
1.38
1.4
1.4
—
—
—
0
0
5
17
2.95
1.36
1.0
1.3
—
—
—
0
0
38
536
0.70
1.35
1.3
1.4
—
—
—
0
0
229
2611
0.86
1.34
2.6
2.7
0.6
0.7
ug/l
0.86
149
1534
23
356
0.64
1.31
1.3
1.6
—
—
—
0
0
6
24
2.50
1.30
5.8
6.5
—
—
—
0
0
5
18
2.78
1.28
1.0
1.1
—
—
—
0
0
8
35
2.29
1.27
11.9
5.7
—
—
—
0
0
56
423
1.33
1.26
1.1
1.1
4.1
1.2
u/ml
0.38
24
183
14
77
1.82
1.25
3.0
1.9
—
—
—
0
0
38
270
1.41
1.24
1.5
1.5
—
—
—
0
0
5
19
2.64
1.21
1.0
1.1
—
—
—
0
0
29
199
1.46
1.14
3.0
3.1
0.9
0.8
nmol/l
0.28
24
152
18
111
1.63
1.12
1.6
1.3
—
—
—
0
0
34
243
1.41
1.10
1.9
1.5
—
—
—
0
0
21
136
1.55
1.08
1.1
1.1
—
—
—
0
0
53
409
1.30
1.07
1.2
1.6
112.2
1831.4
e6/l
1.49
38
333
53
409
1.30
1.07
1.1
1.6
3.5
25.0
e6/l
1.80
35
320
19
121
1.58
1.05
1.2
1.4
—
—
—
0
0
125
1065
1.18
1.04
1.4
1.4
26.9
24.4
iu/l
0.43
113
895
7
34
2.06
1.03
2.0
2.5
—
—
—
0
0
24
163
1.48
1.01
1.3
1.2
—
—
—
0
0
0
29
0.00
0.97
0.0
2.6
—
—
—
0
0
56
444
1.27
0.94
1.1
1.1
6.9
6.1
u/ml
0.12
29
242
9
51
1.77
0.94
2.7
2.3
—
—
—
0
0
15
93
1.62
0.93
1.6
1.4
—
—
—
0
0
15
93
1.62
0.93
1.1
1.2
—
—
—
0
0
25
175
1.43
0.93
1.4
1.6
276.9
282.2
mosm/kgh2o
0.75
20
133
18
118
1.53
0.91
1.1
1.1
1.0
1.0
ratio
—
7
46
60
486
1.24
0.86
1.1
1.1
2.7
1.7
u/ml
0.17
24
202
8
44
1.82
0.86
1.1
13.3
—
—
—
0
0
46
362
1.28
0.84
2.3
2.4
233.5
146.0
ug/min
0.27
31
234
21
297
0.70
0.84
1.1
1.1
2.8
1714.0
iu/ml
—
6
79
45
356
1.27
0.80
1.3
1.4
0.4
0.4
nmol/l
0.10
38
286
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
6
33
1.82
0.79
1.0
1.1
—
—
—
0
0
12
74
1.63
0.78
1.2
1.6
—
—
—
0
0
13
82
1.59
0.78
1.7
2.8
1860.5
2051.0
ml
0.23
13
76
19
132
1.44
0.76
1.1
1.0
3.3
2.6
u/ml
—
7
43
189
2089
0.90
0.75
1.6
1.8
—
—
—
0
0
38
297
1.28
0.75
1.1
1.1
2.2
2.4
u/ml
0.07
12
143
9
53
1.70
0.75
1.4
1.5
—
—
—
0
0
18
124
1.46
0.75
1.5
1.6
7.0
6.4
mmol/l
0.57
11
86
9
54
1.67
0.74
2.1
3.2
—
—
—
0
0
20
142
1.41
0.72
1.2
1.3
0.1
0.7
u/ml
—
7
59
40
318
1.26
0.70
4.9
3.9
—
—
—
0
0
5
27
1.85
0.68
1.2
1.7
—
—
—
0
0
24
179
1.34
0.67
1.0
1.1
—
—
—
0
0
5
93
0.54
0.67
1.4
2.5
43.8
49.3
umol/l
—
5
78
5
28
1.79
0.66
1.4
2.2
—
—
—
0
0
5
28
1.79
0.66
1.2
1.2
—
—
—
0
0
5
28
1.79
0.66
3.0
1.9
—
—
—
0
0
261
2416
1.09
0.66
1.5
1.4
—
—
—
0
0
11
70
1.57
0.65
1.3
1.3
—
—
—
0
0
17
120
1.42
0.64
1.6
4.0
10.1
11.3
%
0.65
17
120
16
112
1.43
0.63
1.6
1.3
4896.3
1780.8
e6/l
—
10
70
46
379
1.22
0.62
1.0
1.1
—
—
—
0
0
46
379
1.22
0.62
1.0
1.1
—
—
—
0
0
15
105
1.43
0.60
1.5
1.2
5.9
6.6
mmol/l
0.48
15
94
8
52
1.54
0.59
1.0
1.0
—
—
—
0
0
18
132
1.37
0.57
1.0
2.2
—
—
—
0
0
12
81
1.48
0.57
1.2
1.1
—
—
—
0
0
24
186
1.29
0.54
2.2
2.8
—
—
—
0
0
37
303
1.23
0.54
1.4
1.2
3.6
4.9
u/ml
0.52
24
135
14
99
1.42
0.54
1.7
1.4
16601.3
35261.6
e6/l
—
8
54
26
205
1.27
0.52
2.7
2.3
—
—
—
0
0
22
170
1.30
0.51
1.3
1.5
—
—
—
0
0
9
65
1.39
0.50
1.0
1.8
—
—
—
0
0
12
168
0.71
0.50
1.4
1.1
—
—
titre
—
0
0
55
474
1.16
0.49
1.9
3.3
—
—
—
0
0
83
740
1.13
0.46
1.3
1.3
237.2
225.6
miu/ml
0.07
29
368
15
111
1.35
0.46
2.1
2.8
34.4
44.0
%
—
5
33
17
129
1.32
0.45
1.3
1.3
—
—
—
0
0
5
83
0.60
0.45
1.0
1.1
—
—
—
0
0
8
120
0.67
0.45
2.0
2.2
—
—
—
0
0
83
744
1.12
0.43
2.6
3.5
—
—
—
0
0
18
139
1.30
0.43
1.1
1.1
—
—
—
0
0
5
32
1.56
0.42
1.0
1.5
17.6
24.0
g/l
—
5
20
26
316
0.82
0.42
1.1
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.6
—
12.7
—
0
15
0
16
0.00
0.41
0.0
1.0
—
1.9
—
0
9
5
34
1.47
0.40
1.4
1.1
—
—
—
0
0
28
335
0.83
0.39
5.9
3.1
20.8
23.6
mg/l
0.18
15
210
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
3.7
—
—
—
0
0
5
76
0.66
0.35
6.4
2.7
—
—
—
0
0
114
1227
0.93
0.33
1.8
1.6
—
—
—
0
0
11
83
1.33
0.32
1.9
2.4
14.2
415.3
ug/l
0.70
11
71
28
239
1.17
0.31
1.2
1.8
—
—
—
0
0
10
131
0.76
0.30
1.0
1.4
—
1.4
—
0
5
33
287
1.15
0.30
1.2
1.2
—
—
—
0
0
14
173
0.81
0.28
1.3
1.4
68.7
72.0
pmol/l
—
6
56
34
298
1.14
0.28
1.1
1.2
—
—
—
0
0
75
690
1.09
0.28
1.5
1.7
—
—
—
0
0
8
62
1.29
0.28
3.1
2.6
—
—
—
0
0
452
4392
1.04
0.27
1.9
1.6
1.5
1.4
mmol/l
1.42
387
3783
42
468
0.90
0.26
1.6
2.0
4.0
4.6
iu/l
0.24
21
169
10
127
0.79
0.25
1.5
1.4
29.8
32.3
nmol/l
—
10
109
92
859
1.07
0.25
1.8
2.5
—
—
—
0
0
195
1866
1.05
0.25
1.4
1.4
—
—
—
0
0
48
528
0.91
0.24
11.7
8.0
—
—
—
0
0
14
115
1.22
0.23
1.7
1.5
—
—
—
0
0
5
38
1.32
0.23
1.0
1.1
—
—
—
0
0
5
38
1.32
0.23
1.0
1.1
—
—
—
0
0
5
38
1.32
0.23
1.0
1.1
—
—
—
0
0
5
41
1.22
0.22
1.2
1.2
0.4
2.9
%
—
5
34
1527
15386
0.97
0.22
5.1
4.9
38.1
38.9
mmol/mol
2.68
1428
14477
0
11
0.00
0.21
0.0
1.7
—
176.4
—
0
11
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
2.1
—
—
—
0
0
235
2432
0.96
0.21
1.9
1.7
—
—
—
0
0
5
43
1.16
0.21
1.2
1.3
55.4
61.8
%
—
5
35
6
52
1.15
0.19
1.7
1.3
—
—
—
0
0
6
52
1.15
0.19
1.2
1.2
—
—
—
0
0
6
53
1.13
0.18
1.5
1.1
—
—
—
0
0
22
195
1.13
0.17
1.1
1.9
—
—
—
0
0
13
110
1.18
0.17
1.6
2.1
1.3
1.9
u/field
—
8
56
131
1364
0.96
0.17
1.2
1.2
95.4
143.3
iu/ml
1.57
42
525
10
120
0.83
0.16
1.2
1.2
—
—
—
0
0
8
68
1.18
0.16
5.5
2.8
—
—
—
0
0
74
700
1.06
0.16
2.2
2.3
—
—
—
0
0
8
72
1.11
0.16
3.1
2.4
—
—
—
0
0
7
86
0.81
0.14
8.3
5.9
—
—
—
0
0
7
86
0.81
0.14
4.1
3.0
—
—
—
0
0
83
869
0.95
0.14
1.6
1.6
308.6
291.0
mu/l
0.19
78
788
36
388
0.93
0.14
1.2
1.3
—
—
—
0
0
12
139
0.86
0.14
2.2
2.7
—
—
—
0
0
115
1108
1.04
0.13
1.9
2.3
—
—
—
0
0
115
1110
1.04
0.13
3.8
3.2
4.5
4.6
pmol/l
0.62
99
997
33
306
1.08
0.13
1.0
1.0
1.0
0.5
u/ml
—
10
70
112
1084
1.04
0.11
1.9
2.3
—
—
—
0
0
114
1105
1.03
0.11
1.9
2.1
—
—
—
0
0
113
1096
1.03
0.10
2.0
2.4
—
—
—
0
0
5
46
1.09
0.09
1.4
2.0
—
—
—
0
0
19
174
1.09
0.09
1.2
1.4
9.4
13.0
mmol/l
—
9
40
38
360
1.06
0.09
1.0
1.1
1.1
4.4
u/ml
2.31
15
136
35
332
1.06
0.08
1.0
1.1
5.1
5.8
u/ml
0.09
17
136
15
164
0.91
0.08
1.0
1.1
231.8
265.3
mg/l
—
10
139
8
78
1.03
0.07
2.0
1.5
—
10.4
—
0
7
7
85
0.82
0.07
1.0
1.0
—
—
—
0
0
16
173
0.92
0.06
1.1
1.2
24.5
42.8
mg/l
3.26
11
140
8
95
0.84
0.06
10.6
6.7
—
—
—
0
0
86
881
0.98
0.06
1.0
1.1
—
—
—
0
0
440
4432
0.99
0.05
3.9
4.1
2.0
2.1
ug/l
0.25
397
4008
43
417
1.03
0.04
1.1
1.1
4.8
2.7
u/ml
0.29
13
103
14
150
0.93
0.04
2.5
3.5
31.3
30.1
mu/l
0.05
14
144
145
1468
0.99
0.04
2.3
2.2
13.1
13.3
nmol/l
0.10
138
1332
104
1026
1.01
0.03
1.9
2.4
—
—
—
0
0
11
118
0.93
0.02
1.3
3.7
—
—
—
0
0
16
168
0.95
0.02
1.1
1.2
—
—
—
0
0
17
178
0.95
0.02
1.8
2.2
19.6
21.3
nmol/l
0.42
17
168
16
167
0.96
0.01
6.3
4.5
152.9
98.6
u/ml
—
8
51
10
95
1.05
0.00
1.8
1.5
—
—
—
0
0
10
99
1.01
0.00
1.0
1.4
—
—
—
0
0
12
118
1.02
0.00
1.0
1.0
—
—
—
0
0
43
427
1.01
0.00
1.1
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
4.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
14
140
1.00
0.00
1.4
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
6.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
274.8
—
0
5
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
5
49
1.02
0.00
1.8
1.5
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CHRONLARGE and mortality.

Females

Parameter HR [95% CI] p-value
CHRONLARGE 1.588 [1.4, 1.8] < 0.001
Birth year 0.996 [0.99, 1.0] 0.373

During the follow-up period (1.1.1998 — 31.12.2019), 567 out of 4996 females with CHRONLARGE died.

Males

Parameter HR [95% CI] p-value
CHRONLARGE 1.464 [1.3, 1.64] < 0.001
Birth year 0.991 [0.98, 1.0] 0.042

During the follow-up period (1.1.1998 — 31.12.2019), 652 out of 4962 males with CHRONLARGE died.

Mortality risk

Mortality risk for people of age

years, who have CHRONLARGE.

N-year risk Females Males
1 0.185% 0.252%
5 1.088% 1.743%
10 2.417% 4.323%
15 4.304% 8.995%
20 7.781% 15.209%

Relationships between endpoints

Index endpoint: CHRONLARGE – Crohn's disease of large intestine

GWS hits: 8

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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