glaucoma: Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2592 |
4. Check minimum number of eventsNone |
2592 |
5. Include endpointsNone |
2592 |
6. Filter based on genotype QC (FinnGen only) |
2592 |
Control definitions (FinnGen only)
- Control exclude
- H7_GLAUCOMA
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Other and unspecified glaucoma
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 27050 | 16252 | 10529 |
| Only index persons | 21210 | 13148 | 8062 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.40 | 0.47 | 0.29 |
| Only index persons | 0.42 | 0.48 | 0.31 |
| Median age at first event (years) | |||
| Whole population | 73.83 | 76.31 | 70.15 |
| Only index persons | 74.25 | 76.75 | 70.16 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2592 | 1423 | 1169 |
| Unadjusted period prevalence (%) | 0.50 | 0.49 | 0.52 |
| Median age at first event (years) | 70.83 | 71.31 | 70.25 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2285
- Matched controls
- 22860
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
1242.2
323.0
409
*
S01EX03
ATC
NA
83.4
323.0
518
80
S01ED51
ATC
timolol, combinations; ophthalmic
117.7
323.0
1502
365
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
335.2
323.0
614
25
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
665.4
323.0
909
23
S01EE05
ATC
tafluprost; ophthalmic
51.8
323.0
452
108
H40.0
ICD-10 Finland
Glaucoma suspect
225.1
323.0
703
45
H40.8
ICD-10 Finland
Other glaucoma
2079.9
323.0
340
*
S01EC03
ATC
dorzolamide; ophthalmic
105.0
323.0
355
40
S01EE03
ATC
bimatoprost; ophthalmic
77.7
323.0
388
60
S01EC01
ATC
acetazolamide; systemic
51.1
323.0
430
103
114
Kela drug reimbursment
Glaucoma
252.9
323.0
1890
420
S01EE04
ATC
travoprost; ophthalmic
69.6
323.0
417
73
S01EC04
ATC
brinzolamide; ophthalmic
123.5
323.0
733
87
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
4315.4
323.0
375
*
S01ED01
ATC
timolol; ophthalmic
65.9
323.0
822
193
S01EE01
ATC
latanoprost; ophthalmic
91.4
323.0
1232
288
H40.9
ICD-10 Finland
Glaucoma, unspecified
4872.0
323.0
1786
16
XCK00
NOMESCO Finland
Perimetry
28.8
323.0
761
389
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
2682.2
264.7
251
*
XCH00
NOMESCO Finland
Eye pressure measurement
16.2
227.7
384
282
H40.11
ICD-10 Finland
Low pressure glaucoma
281.2
203.5
205
8
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
32.1
200.3
268
94
XCW99
NOMESCO Finland
Other investigative procedure of eye
5.9
196.1
626
1362
S01ED02
ATC
betaxolol; ophthalmic
106.7
196.0
213
22
S01EC54
ATC
brinzolamide, combinations; ophthalmic
126.7
184.4
197
17
Z96.1
ICD-10 Finland
Presence of intraocular lens
4.7
184.1
769
2239
H40
ICD-10 Finland
Glaucoma
58.9
181.6
214
40
CHD00
NOMESCO Finland
Laser trabeculoplasty
597.8
170.6
167
*
XCK10
NOMESCO Finland
Photography of fundus of eye
5.3
157.8
546
1270
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.4
153.2
658
1914
S01EB01
ATC
pilocarpine; ophthalmic
107.5
147.2
160
16
WX140
NOMESCO Finland
Parabulbar anesthesy
9.0
145.0
325
411
CHC05
NOMESCO Finland
Iridotomy
70.5
143.1
164
25
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
5.7
141.1
454
958
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
36.5
140.6
182
54
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.0
136.2
1341
7300
37520
ICD-8 Finland
Glaucoma, Secondary
+∞
134.7
128
*
H40.22
ICD-10 Finland
Chronic glaucoma with closed ventricular angle
+∞
126.2
120
*
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
1264.7
124.2
120
*
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
+∞
122.0
116
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.8
120.4
1273
7027
S01EA03
ATC
apraclonidine; ophthalmic
32.5
118.9
158
52
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
+∞
111.4
106
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.7
106.6
1199
6679
XCH05
NOMESCO Finland
Eye pressure longterm registration
348.8
100.9
101
*
H25.1
ICD-10 Finland
Senile nuclear cataract
2.6
99.3
1074
5769
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
211.2
98.3
101
5
S01EA02
ATC
dipivefrine; ophthalmic
503.9
98.2
97
*
3651A
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA SIMPLEX (AVOKULMA)]
+∞
93.4
89
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
7.9
93.1
224
310
H40.20
ICD-10 Finland
Acute glaucoma with closed ventricular angle
902.6
89.3
87
*
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
+∞
74.4
71
*
S01BA07
ATC
fluorometholone; ophthalmic (corticosteroids, plain)
12.4
72.5
134
114
H20.1
ICD-10 Finland
Chronic iridocyclitis
18.9
70.8
110
61
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
107.7
67.3
73
7
3656X
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA SECUNDARIA ALIA SEU NUD]
+∞
67.0
64
*
CHD99
NOMESCO Finland
Other filtering operation
+∞
67.0
64
*
H40.19
ICD-10 Finland
Other primary glaucoma with open ventricular angle
+∞
65.9
63
*
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
+∞
63.8
61
*
CJB10
NOMESCO Finland
Laser discission of secondary cataract
3.1
63.8
393
1419
ZXA10
NOMESCO Finland
Bilateral
2.5
62.3
621
3004
H26.4
ICD-10 Finland
After-cataract
2.9
60.3
422
1658
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
19.9
57.8
88
46
CHD35
NOMESCO Finland
Laser goniopuncture
+∞
57.5
55
*
37510
ICD-8 Finland
Glaucoma, Chronicum simplex
+∞
55.4
53
*
F93
ICPC
Glaucoma
99.2
53.0
58
6
ZXA00
NOMESCO Finland
Right side
2.1
49.9
805
4774
CS494
NOMESCO Finland
Other visual field testing
11.2
48.9
94
87
H34.8
ICD-10 Finland
Other retinal vascular occlusions
6.7
47.6
126
198
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
4.9
47.5
163
352
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
6.6
45.6
122
195
3708
FHL
Trabeculectomy or equivalent
+∞
44.9
43
*
ZXA05
NOMESCO Finland
Left side
2.0
44.6
754
4507
WX002
NOMESCO Finland
Sedation and analgesia
2.2
44.2
564
2996
H40.1
ICD-10 Finland
Primary open-angle glaucoma
156.4
43.9
46
*
H40.3
ICD-10 Finland
Glaucoma secondary to eye trauma
+∞
41.8
40
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.6
41.4
200
593
S01BC03
ATC
diclofenac; ophthalmic
5.4
38.6
120
232
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
5.1
37.8
123
250
H04.10
ICD-10 Finland
Dry eye syndrome
2.7
36.8
272
1081
H40.12
ICD-10 Finland
Pigmentary glaucoma
362.8
36.1
36
*
37597
ICD-8 Finland
Glaucoma, Suspicio glaucomatis
+∞
35.5
34
*
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
3.2
35.1
201
677
3656C
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA NEOVASCULARE]
+∞
34.5
33
*
CFW99
NOMESCO Finland
Other operation on conjunctiva
177.6
33.8
35
*
CS2P4
NOMESCO Finland
Optic nerve head imaging
94.0
33.8
37
*
3650A
ICD-9 Finland
Glaucoma, Borderline glaucoma [glaucoma suspect][SUSPICIO GLAUCOMATIS (AVOKULMA)]
+∞
33.4
32
*
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
7.4
33.4
81
113
S01FA01
ATC
atropine; ophthalmic
17.4
32.4
51
30
CKC12
NOMESCO Finland
Photocoagulation of retina
4.1
32.2
130
330
H16.0
ICD-10 Finland
Corneal ulcer
3.8
32.2
141
385
XCD10
NOMESCO Finland
Electrophysiological examination of eye
4.8
31.6
108
232
3659X
ICD-9 Finland
Glaucoma, Unspecified glaucoma
+∞
31.3
30
*
3711
FHL
Cyclodiateria or cryocoagulation
+∞
31.3
30
*
H26.2
ICD-10 Finland
Complicated cataract
7.8
30.8
72
95
CK2P4
NOMESCO Finland
Optic nerve head light layer imaging (OCT)
306.3
29.9
30
*
36402
ICD-8 Finland
Iritis, Iridocyclitis, uveitis chronica
57.5
29.2
34
6
CKD40
NOMESCO Finland
Endophotocoagulation of retina
7.8
28.8
67
88
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.1
28.7
361
1863
SPAT1009
SPAT
Measurement of intraocular pressure
7.6
28.7
68
92
37598
ICD-8 Finland
Glaucoma, Aliud definitum
+∞
28.2
27
*
H33.0
ICD-10 Finland
Retinal detachment with retinal break
4.3
28.1
107
257
H43.1
ICD-10 Finland
Vitreous haemorrhage
4.9
27.6
92
193
3719
FHL
Other measure in this category
+∞
27.1
26
*
3651B
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA CAPSULARE (AVOKULMA)]
+∞
27.1
26
*
ZXC20
NOMESCO Finland
Use of chemical agents
4.7
26.5
93
206
WX110
NOMESCO Finland
Local anesthesy
1.6
25.9
1329
10608
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
6.1
25.8
71
119
S01FA04
ATC
cyclopentolate; ophthalmic
7.9
25.7
59
76
37872
ICD-8 Finland
Other diseases of eye, Aphakia artefacta, acquisita
27.9
24.5
33
12
XCW10
NOMESCO Finland
Assessment of vision
15.8
24.1
39
25
TCG20
NOMESCO Finland
Laser suture lysis in cornea or sclera
+∞
22.9
22
*
H18.1
ICD-10 Finland
Bullous keratopathy
24.1
22.2
31
13
CKC20
NOMESCO Finland
Cryopexy of undetached retina
21.6
22.1
32
15
3641A
ICD-9 Finland
Disorders of iris and ciliary body, Chronic iridocyclitis
52.5
22.1
26
5
H44.5
ICD-10 Finland
Degenerated conditions of globe
63.1
21.9
25
*
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
11.0
21.6
41
38
H57.1
ICD-10 Finland
Ocular pain
4.1
21.5
86
218
H27.0
ICD-10 Finland
Aphakia
18.0
20.9
32
18
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
20.8
1472
12356
R4110
NOMESCO Finland
Physiotherapy
1.6
20.5
610
4164
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
20.2
20.4
30
15
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
14.4
20.3
34
24
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.6
20.2
71
159
WX144
NOMESCO Finland
Subconjunctival anesthesy
5.2
20.0
63
125
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.2
19.9
218
1052
H21.0
ICD-10 Finland
Hyphaema
22.7
19.1
27
12
3656F
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA POST UVEITIDEM]
+∞
18.8
18
*
CKD15
NOMESCO Finland
Injection of vitreous substitute
13.5
18.7
32
24
H54.4
ICD-10 Finland
Blindness, monocular
15.2
18.4
30
20
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
3.0
18.4
106
359
A10AA02
ATC
NA
3.1
18.3
105
355
37599
ICD-8 Finland
Glaucoma, Unspecified
+∞
17.7
17
*
3793A
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[APHAKIA]
37.0
17.6
22
6
CKD20
NOMESCO Finland
Removal of vitreous body substitute
13.2
17.4
30
23
TCG10
NOMESCO Finland
Removal of sutures from cornea
10.1
17.4
34
34
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
31.7
17.0
22
7
J01DB01
ATC
cefalexin; oral
1.5
17.0
1676
14749
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
3.1
16.8
93
308
H40.29
ICD-10 Finland
Other [primary] glaucoma with closed ventricular angle
+∞
16.7
16
*
A10AA01
ATC
NA
3.8
16.3
70
190
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
2.6
16.2
117
458
S01BC05
ATC
ketorolac; ophthalmic
2.3
16.2
150
670
H3603, E103
ICD-10 Finland
NA
7.3
16.0
38
53
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
21.1
16.0
23
11
H27.1
ICD-10 Finland
Dislocation of lens
10.8
16.0
30
28
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
7.8
15.8
36
47
CFB00
NOMESCO Finland
Suture of conjunctiva
33.6
15.7
20
6
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
15.8
15.7
25
16
CKC15
NOMESCO Finland
Panretinal photocoagulation
6.1
15.6
42
70
CHC00
NOMESCO Finland
Iridotomy
161.0
15.5
16
*
A10AE04
ATC
insulin glargine; parenteral
1.9
15.3
230
1259
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.0
15.3
90
311
WX142
NOMESCO Finland
Sub-tenon anesthesy
9.8
15.2
30
31
H20.8
ICD-10 Finland
Other iridocyclitis
13.1
15.2
26
20
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
8.1
15.0
33
41
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
3.3
15.0
74
226
3643
FHL
Vitrectomy through pars Plana
25.2
14.7
20
8
S01EX
ATC
Other antiglaucoma preparations
+∞
14.6
14
*
37512
ICD-8 Finland
Glaucoma, Chronicum capsulare
+∞
14.6
14
*
CHD10
NOMESCO Finland
Trabeculectomy
+∞
14.6
14
*
TCA15
NOMESCO Finland
Retrobulbar therapeutic injection into orbit
150.9
14.5
15
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
14.4
369
2392
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
7.2
14.3
34
48
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
4.3
14.1
52
124
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
8.0
14.0
31
39
N02BE01
ATC
paracetamol; systemic, rectal
1.5
14.0
1860
16955
CFD10
NOMESCO Finland
Repair of conjunctiva
30.2
13.9
18
6
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
13.8
252
1474
37404
ICD-8 Finland
Cataract, Secundaria
53.7
13.8
16
*
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.0
13.6
180
942
CG2T4
NOMESCO Finland
Topography assessment of cornea
7.2
13.5
32
45
A28
ICPC
Limited function/disability NOS
1.6
13.5
447
3090
H26.02
ICD-10 Finland
Presenil cataract
3.4
13.5
65
196
3663A
ICD-9 Finland
Cataract secondary to ocular disorders
12.9
13.4
23
18
F38
ICPC
Eye, Other laboratory test NEC
12.9
13.4
23
18
37403
ICD-8 Finland
Cataract, Complicata
25.9
13.4
18
7
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
8.1
13.3
29
36
F43
ICPC
Eye, Other diagnostic procedure
4.2
13.2
49
118
T89
ICPC
Diabetes insulin dependent
3.0
13.2
76
260
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
7.1
13.0
31
44
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
4.1
12.8
49
122
S01EX05
ATC
netarsudil; ophthalmic
+∞
12.5
12
*
Q15.0
ICD-10 Finland
Congenital glaucoma
+∞
12.5
12
*
L28
ICPC
Limited function/disability (L)
1.5
12.5
424
2942
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
2.6
12.3
89
351
R53
ICD-10 Finland
Malaise and fatigue
1.5
12.2
477
3413
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.1
12.1
134
652
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
4.8
12.1
39
82
CKD60
NOMESCO Finland
Anterior vitrectomy
4.7
12.0
40
87
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
10.1
12.0
23
23
36400
ICD-8 Finland
Iritis, Iridocyclitis acuta
7.6
11.9
27
36
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
4.1
11.8
45
112
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
11.8
527
3879
A98
ICPC
Health maint/preventive medicine
1.5
11.6
1934
17952
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
19.0
11.6
17
9
3652A
ICD-9 Finland
Glaucoma, Primary angle-closure glaucoma[AKUUTTI AHDASKULMAGLAUKOOMA]
+∞
11.5
11
*
CHF15
NOMESCO Finland
Cryotherapy of ciliary body
+∞
11.5
11
*
37511
ICD-8 Finland
Glaucoma, Chronicum irritativum sive congestivum
+∞
11.5
11
*
CHC03
NOMESCO Finland
Laser iridoplasty
120.6
11.4
12
*
CKC10
NOMESCO Finland
Local photocoagulation of retina
3.1
11.4
60
194
CD2S4
NOMESCO Finland
Photography of eye
9.6
11.2
22
23
H25.0
ICD-10 Finland
Senile incipient cataract
1.9
11.0
169
934
H02AB06
ATC
prednisolone; systemic
1.4
11.0
982
8161
F99
ICPC
Eye/adnexa disease other
6.3
10.9
28
45
R05
ICD-10 Finland
Cough
1.5
10.7
380
2655
25002
ICD-8 Finland
Diabetes mellitus, Retinopathia diabetica
9.6
10.7
21
22
CHB99
NOMESCO Finland
Other operation on anterior chamber and anterior chamber angle
60.3
10.6
12
*
WX402
NOMESCO Finland
General anaesthesia
1.6
10.6
278
1803
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
3.7
10.6
44
119
H01.0
ICD-10 Finland
Blepharitis
2.3
10.6
99
448
S01BA09
ATC
clobetasone; ophthalmic
14.3
10.5
17
12
H40.21
ICD-10 Finland
Intermittent glaucoma with closed ventricular angle
+∞
10.4
10
*
H40.6
ICD-10 Finland
Glaucoma secondary to drugs
+∞
10.4
10
*
3652B
ICD-9 Finland
Glaucoma, Primary angle-closure glaucoma[KROONINEN AHDASKULMAGLAUKOOMA]
+∞
10.4
10
*
S01FA06
ATC
tropicamide; ophthalmic
32.7
10.3
13
*
-1
NOMESCO Finland
NA
1.4
10.3
532
4013
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
2.8
10.3
64
231
M79.6
ICD-10 Finland
Pain in limb
1.4
10.2
684
5405
H54.0
ICD-10 Finland
Blindness, binocular
13.2
10.2
17
13
S01AD03
ATC
aciclovir; ophthalmic
2.3
10.0
93
421
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
10.0
499
3740
R50.9
ICD-10 Finland
Fever, unspecified
1.6
9.9
272
1787
3620B
ICD-9 Finland
Other retinal disorders, Diabetic retinopathy[RETINOPATHIA DIABETICA PROLIFERATIVA]
20.1
9.8
14
7
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
3.9
9.8
39
102
S01FA02
ATC
scopolamine; ophthalmic
4.6
9.7
32
70
C09CA01
ATC
losartan; oral
1.4
9.7
542
4141
SPAT1262
SPAT
Handing over of treatment supplies
1.5
9.6
385
2759
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
3.3
9.5
46
142
F29
ICPC
Eye symptom/complaint other
1.8
9.4
156
885
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
7.6
9.4
21
28
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
3.7
9.4
39
106
3623C
ICD-9 Finland
Other retinal disorders, Retinal vascular occlusion[OCCLUSIO VENAE CENTRALIS RETINAE]
+∞
9.4
9
*
3702
FHL
Trabeculotomy
+∞
9.4
9
*
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
9.4
459
3419
3793C
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[PSEUDOPHAKIA]
6.9
9.3
22
32
E10
ICD-10 Finland
Type 1 diabetes mellitus
3.9
9.3
37
97
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
4.7
9.2
30
65
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
7.7
9.1
20
26
E0000UV
ATC
NA
1.3
9.1
741
6018
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
5.6
9.0
25
45
CWD00
NOMESCO Finland
Reoperation for superficial heamorrhage in eye and adjacent structures
36.8
9.0
11
*
Z94.7
ICD-10 Finland
Corneal transplant status
7.1
9.0
21
30
S01AA01
ATC
chloramphenicol; ophthalmic (antibiotics)
2.0
9.0
107
539
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
4.9
9.0
28
58
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
5.2
8.9
26
50
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
8.9
354
2530
A02BC02
ATC
pantoprazole; systemic
1.3
8.9
1357
12050
H16.9
ICD-10 Finland
Keratitis, unspecified
3.5
8.8
39
112
2504B
ICD-9 Finland
Diabetes mellitus, Diabetes with renal manifestations[DIABETES MELLITUS CUM COMPLICATIONE OCULI ,TYYPPI I]
9.5
8.8
17
18
-44
ICPC
Preventive immunization/medic
1.7
8.7
189
1166
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
8.7
592
4665
3792A
ICD-9 Finland
Other disorders of eye, Disorders of vitreous body
50.2
8.7
10
*
S18
ICPC
Laceration/cut
1.3
8.6
849
7085
C08CA01
ATC
amlodipine; oral
1.3
8.6
831
6915
CA1ME
NOMESCO Finland
Ultrasound oculometry
4.3
8.5
30
71
CDC40
NOMESCO Finland
Evisceration of eye with insertion of prosthesis
90.4
8.4
9
*
3649
FHL
Other measure in this category
90.4
8.4
9
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.1
8.4
94
464
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
8.4
592
4692
3656B
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUKOMASYKLIITTINEN KRIISI,SYNDR POSSNER-SCHOSSMAN]
+∞
8.3
8
*
36401
ICD-8 Finland
Iritis, Iridocyclitis glaucomatosa. Syndroma Posner-Schlossman, heterochromia iridis
+∞
8.3
8
*
37500
ICD-8 Finland
Glaucoma, Primary, acute
+∞
8.3
8
*
H18.8
ICD-10 Finland
Other specified disorders of cornea
5.5
8.3
23
42
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
7.1
8.2
19
27
CG2S4
NOMESCO Finland
Photography of cornea
7.1
8.2
19
27
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
8.2
947
8056
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.4
8.1
539
4223
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
8.1
792
6585
CDC00
NOMESCO Finland
Enucleation of eye
33.5
8.1
10
*
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
17.2
8.1
12
7
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
2.6
8.1
57
226
103
Kela drug reimbursment
Diabetes, insulin-treated
1.3
8.0
595
4743
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
8.0
429
3245
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
7.9
686
5596
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
2.5
7.9
61
252
3744
FHL
Pericardial identification surgery with coagulation (includes epi- and intrascleral indications and eg Lincoff catheter)
13.1
7.9
13
10
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
1.8
7.8
135
778
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
1.9
7.8
104
547
3661A
ICD-9 Finland
Cataract, Senile cataract
2.7
7.8
50
186
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
4.7
7.8
25
54
WX302
NOMESCO Finland
Thoracal epidural anesthesy
1.9
7.8
104
549
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
7.8
608
4885
TCH12
NOMESCO Finland
Sample aspiration from anterior chambre
45.1
7.7
9
*
3690A
ICD-9 Finland
Blindness and low vision, Profound impairment, both eyes
45.1
7.7
9
*
UJF32
NOMESCO Finland
Coloscopy
1.3
7.7
547
4332
H25.8
ICD-10 Finland
Other senile cataract
1.5
7.6
299
2127
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.3
7.6
580
4638
CGF35
NOMESCO Finland
Repair of cornea using graft
25.1
7.6
10
*
A10AE05
ATC
insulin detemir; parenteral
1.9
7.6
110
599
R42
ICD-10 Finland
Dizziness and giddiness
1.4
7.5
493
3849
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
2.3
7.5
66
293
3102
FHL
Enucleation
80.3
7.4
8
*
CHW99
NOMESCO Finland
Other operation on anterior chamber, anterior chamber angle, iris or ciliary body
80.3
7.4
8
*
H31.4
ICD-10 Finland
Choroidal detachment
80.3
7.4
8
*
H44.4
ICD-10 Finland
Hypotony of eye
80.3
7.4
8
*
M54.5
ICD-10 Finland
Low back pain
1.3
7.4
569
4556
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
6.0
7.4
19
32
3656E
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA POSTTRAUMATICUM]
+∞
7.3
7
*
7432A
ICD-9 Finland
Congenital anomalies of eye, Buphthalmos[GLAUCOMA CONGENITUM]
+∞
7.3
7
*
37513
ICD-8 Finland
Glaucoma, Chronicum pigmentosum
+∞
7.3
7
*
R3120
NOMESCO Finland
Training in mobility skills
10.9
7.3
13
12
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.4
7.3
424
3246
S01GX01
ATC
cromoglicic acid; ophthalmic
1.5
7.3
293
2097
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
1.6
7.3
173
1097
36409
ICD-8 Finland
Iritis, Unspecified
15.8
7.2
11
7
N03AX16
ATC
pregabalin; oral
1.4
7.2
446
3452
37700
ICD-8 Finland
Other diseases of retina and optic nerve, Haemorrhagia corporis vitrei
30.1
7.1
9
*
S01AX11
ATC
[U] ofloxacin; ophthalmic
1.9
7.1
97
517
TPH07
NOMESCO Finland
Cathetrisation of artery
1.5
7.0
222
1509
C03CA01
ATC
furosemide; systemic
1.3
7.0
801
6762
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.4
7.0
401
3062
XCD20
NOMESCO Finland
Photoangiography of eye
2.5
7.0
50
201
SPAT1014
SPAT
Treatment of eyes
2.4
7.0
55
230
H33.5
ICD-10 Finland
Other retinal detachments
4.5
7.0
23
52
AA1AD
NOMESCO Finland
CT of head and brain
1.3
6.9
537
4296
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.5
6.9
226
1547
S01BC01
ATC
indometacin; ophthalmic
13.8
6.9
11
8
N30.0
ICD-10 Finland
Acute cystitis
1.4
6.9
308
2250
C08CA13
ATC
lercanidipine; oral
1.4
6.9
309
2257
F28
ICPC
Limited function/disability (F)
4.8
6.8
21
44
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.5
6.8
218
1486
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
6.8
328
2429
CGG45
NOMESCO Finland
Full thickness transplantation of cornea using homograft
9.3
6.8
13
14
J01FF01
ATC
clindamycin; systemic
1.3
6.8
494
3915
H44.1
ICD-10 Finland
Other endophthalmitis
16.7
6.7
10
6
H11.3
ICD-10 Finland
Conjunctival haemorrhage
2.0
6.7
81
411
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.5
6.7
212
1441
H3603, E113
ICD-10 Finland
NA
3.5
6.7
29
84
S97
ICPC
Chronic ulcer skin
1.7
6.7
128
764
3747
FHL
Combined ablation and vitreous surgery with coagulation
22.6
6.7
9
*
H04AA01
ATC
glucagon; nasal, parenteral
3.0
6.7
35
117
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
6.7
439
3424
Z71.8
ICD-10 Finland
Other specified counselling
1.4
6.7
396
3042
L20.0
ICD-10 Finland
Besnier prurigo
2.1
6.6
69
329
H53.4
ICD-10 Finland
Visual field defects
2.5
6.6
47
187
H26.3
ICD-10 Finland
Drug-induced cataract
5.2
6.6
19
37
J05AB01
ATC
aciclovir; systemic
1.4
6.6
374
2845
H53.1
ICD-10 Finland
Subjective visual disturbances
1.8
6.6
113
651
H34.1
ICD-10 Finland
Central retinal artery occlusion
4.6
6.6
21
46
J01MA02
ATC
ciprofloxacin; systemic
1.3
6.6
809
6887
JN4BD
NOMESCO Finland
Extensive body CT
1.5
6.5
236
1651
CJF45
NOMESCO Finland
Removal and implantation of artificial lens in anterior chamber with iridectomy or iridotomy
10.0
6.5
12
12
H18.4
ICD-10 Finland
Corneal degeneration
6.9
6.5
15
22
XX3DW
NOMESCO Finland
Time consuming IT work
1.5
6.5
198
1334
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.5
6.5
195
1311
TKC20
NOMESCO Finland
Catheterisation of bladder
1.6
6.5
174
1139
F01
ICPC
Eye pain
2.5
6.5
49
202
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
5.3
6.5
18
34
-69
ICPC
Other reason for encounter NEC
1.9
6.4
83
435
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.6
6.4
142
884
3745
FHL
Hard membrane girding, cerclage with coagulation
14.3
6.4
10
7
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
1.7
6.4
120
711
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
4.1
6.4
23
57
TNX34
NOMESCO Finland
Major custom molded cast, unspecified region
2.9
6.4
35
121
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
8.2
6.3
13
16
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.6
6.3
157
1010
3654A
ICD-9 Finland
Glaucoma associated with congenital anomalies, dystrophies and systemic syndromes
+∞
6.3
6
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
6.2
361
2758
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
3.2
6.1
30
96
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
4.7
6.1
19
41
R60.0
ICD-10 Finland
Localized oedema
1.4
6.1
240
1711
K59.09
ICD-10 Finland
Constipation, unspecified
1.7
6.1
131
812
J01CA04
ATC
amoxicillin; systemic
1.3
6.1
1522
14023
H10.5
ICD-10 Finland
Blepharoconjunctivitis
2.9
6.1
33
114
37600
ICD-8 Finland
Detachment of retina, Primaria
10.0
6.0
11
11
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1048
6271
2.13
71.83
4.0
3.4
0.6
0.5
e6/l
0.22
806
4810
1115
6837
2.11
71.57
4.1
3.5
48.7
80.9
e6/l
1.22
874
5296
1268
8598
1.93
57.18
12.7
10.2
0.0
0.0
e9/l
0.17
1035
6912
1934
15417
2.00
50.27
27.5
21.2
14.0
13.9
%
1.04
1886
15023
784
4820
1.90
45.04
3.2
2.7
5.7
5.4
e6/l
0.14
693
4228
642
3692
1.98
45.02
3.4
3.0
2.3
2.6
e6/l
0.44
346
2056
458
2347
2.16
43.82
4.2
3.7
—
—
—
0
0
634
3932
1.81
33.85
3.3
2.9
5.8
1.3
e6/l
0.47
338
2290
1737
14291
1.65
30.34
6.3
5.3
1364.0
3135.6
e6/l
0.62
18
236
1904
16103
1.69
29.23
8.5
7.6
80.8
81.1
u/l
0.12
1779
15020
2085
18186
1.75
27.27
22.4
16.4
73.2
72.6
ml/min/173m2
0.60
1783
15085
1238
9581
1.56
26.34
7.3
6.0
24.2
26.2
%
7.54
1150
8810
1958
16906
1.65
25.29
25.2
18.9
37.8
38.3
%
1.10
1304
10511
2202
19630
1.81
25.20
22.9
17.3
28.6
26.7
mg/l
1.69
1897
16073
1318
10417
1.54
25.00
7.0
5.8
1.2
1.2
mmol/l
0.80
1219
9321
506
3182
1.73
24.81
2.8
2.5
20.8
21.7
%
0.72
441
2661
1428
11500
1.54
24.74
7.4
6.6
1.2
1.2
mmol/l
0.26
1146
9674
1553
12761
1.54
24.34
5.8
4.7
6.9
6.9
mmol/l
0.39
1494
12011
1206
9411
1.53
23.85
7.2
5.8
60.8
58.6
%
7.49
1127
8706
1217
9569
1.51
22.88
11.8
10.9
1.3
1.4
inr
0.07
459
2494
332
1884
1.87
22.83
4.1
3.5
1.2
1.2
mmol/l
0.25
298
1620
545
3583
1.66
22.39
3.1
2.9
0.8
0.8
mmol/l
0.08
502
3283
670
4644
1.60
22.19
4.5
4.1
324.5
325.7
ng/l
0.00
592
3993
2266
20572
1.81
21.74
26.8
20.6
139.3
139.5
mmol/l
5.50
2210
19990
2269
20613
1.81
21.65
27.1
20.7
4.0
4.0
mmol/l
1.42
2211
20000
1242
9879
1.49
21.64
5.2
4.6
34.1
34.6
g/l
2.59
1145
9081
246
1294
2.00
21.15
5.2
6.7
24.7
25.0
mmol/l
0.50
241
1283
1419
11638
1.48
20.94
10.1
8.7
4.5
4.3
e9/l
3.31
1221
10023
1247
9999
1.48
20.43
6.1
5.7
0.0
0.0
estimate
0.00
307
1795
1244
9973
1.48
20.38
4.5
4.2
0.0
0.0
estimate
0.00
303
1798
511
3383
1.64
20.20
2.9
2.5
2.2
2.3
g/l
2.80
470
3093
542
3652
1.61
19.91
2.9
2.5
11.3
12.1
umol/l
1.99
500
3333
345
2067
1.77
19.72
6.9
5.9
1.3
1.4
mmol/l
0.54
331
1978
1367
11212
1.46
19.62
6.5
6.1
11.9
12.1
umol/l
0.30
1299
10593
2249
20501
1.73
19.59
13.2
11.2
23.9
24.6
u/l
1.03
2148
19568
816
6049
1.51
19.51
2.4
2.3
3.1
3.1
mg/l
0.06
688
5097
1255
10137
1.46
19.44
4.5
4.2
0.0
0.0
estimate
0.19
298
1776
444
2900
1.64
18.36
1.9
1.8
—
—
—
0
0
2300
21184
1.76
18.17
32.6
25.4
244.8
243.7
e9/l
0.30
2213
20484
2300
21187
1.76
18.12
32.6
25.4
4.3
4.4
e12/l
7.61
2190
20407
2300
21191
1.76
18.06
32.9
25.5
129.6
131.9
g/l
10.50
2255
20750
441
2887
1.64
18.05
1.9
1.8
—
—
—
0
0
2300
21193
1.76
18.02
32.6
25.4
7.1
6.9
e9/l
1.74
2193
20413
2243
20551
1.68
17.66
26.3
20.4
82.6
81.9
umol/l
0.40
2243
20545
280
1630
1.80
17.56
1.7
1.7
—
—
—
0
0
635
4590
1.51
16.68
3.6
3.0
2.5
2.5
mmol/l
0.59
542
4005
292
1766
1.74
16.01
1.7
1.6
—
—
—
0
0
321
1996
1.69
15.91
3.2
2.3
43.7
59.7
u/l
0.26
264
1687
511
3562
1.54
15.80
1.9
2.0
30.0
30.0
s
0.05
499
3435
797
6097
1.44
15.48
3.1
3.1
36.3
35.2
u/l
0.12
735
5756
577
4149
1.50
15.37
1.9
1.9
—
—
—
0
0
1983
17853
1.47
14.95
5.3
5.0
2.0
2.1
mu/l
0.69
1749
15955
1180
9733
1.39
14.68
2.3
2.1
91.9
93.6
pmol/l
0.61
564
4935
974
7785
1.40
14.58
3.7
3.3
2.4
2.4
mmol/l
0.44
845
6608
1069
8689
1.39
14.45
2.5
2.2
78.1
79.8
nmol/l
1.20
920
7579
1018
8222
1.39
14.23
3.3
2.8
161.9
146.5
ug/l
0.60
899
7413
131
635
2.12
14.04
2.0
1.7
—
—
—
0
0
1706
15021
1.40
13.94
4.8
4.2
15.9
14.7
mm/h
2.05
1552
13668
92
389
2.41
13.66
1.9
1.9
1.8
1.7
mmol/l
0.52
92
379
109
500
2.23
13.43
2.3
2.5
15.8
15.9
%
0.07
47
262
742
5752
1.41
12.93
1.7
1.6
19.2
20.3
nmol/l
1.21
628
4828
193
1115
1.79
12.36
4.2
3.4
24.1
24.2
mmol/l
0.09
184
1004
1137
9536
1.34
11.80
2.7
2.4
—
—
—
0
0
827
6641
1.36
11.31
3.1
2.5
63.8
58.0
u/l
0.50
755
6065
14
16
8.79
11.11
7.5
4.3
—
—
—
0
0
229
1430
1.66
11.08
1.6
1.5
—
—
—
0
0
205
1246
1.70
10.99
8.9
8.0
24.0
24.4
mmol/l
0.97
190
1151
854
6922
1.35
10.90
2.2
2.2
189.2
213.3
u/l
0.47
791
6448
421
3031
1.46
10.78
6.7
5.0
1.0
1.0
mmol/l
0.12
385
2769
1143
9691
1.32
10.62
4.5
4.2
—
—
—
0
0
339
2344
1.51
10.59
2.9
2.5
9.0
9.8
umol/l
0.22
292
2037
1656
14814
1.33
10.35
4.3
4.1
15.2
15.1
pmol/l
0.38
1459
13147
924
7648
1.32
10.02
3.1
3.2
2009.8
1861.8
ng/l
0.35
795
6625
139
777
1.83
9.95
2.1
1.8
38.5
39.1
u/l
0.10
124
660
1983
18294
1.36
9.56
7.4
6.4
42.1
40.8
mmol/mol
5.54
1766
16559
2049
19043
1.36
9.08
5.1
5.0
6.1
6.1
mmol/l
1.39
1776
16911
41
143
2.90
9.01
1.2
1.1
—
—
—
0
0
155
929
1.71
8.77
1.7
2.5
10.0
10.3
g/l
0.33
125
764
162
987
1.68
8.63
1.7
2.5
4.0
3.8
g/l
0.89
117
688
162
989
1.68
8.57
1.7
2.5
—
—
—
0
0
162
990
1.68
8.54
1.7
2.5
7.7
7.5
g/l
0.80
118
715
322
2301
1.46
8.48
4.1
3.3
5.8
5.8
kpa
0.16
311
2237
299
2107
1.47
8.46
8.3
6.0
11.5
11.0
mmol/l
0.51
284
1978
109
595
1.87
8.45
1.4
1.4
—
—
—
0
0
109
595
1.87
8.45
1.4
1.4
—
—
—
0
0
179
2743
0.63
8.32
4.9
4.8
32.8
33.5
%
0.34
110
1768
319
2286
1.45
8.27
4.1
3.3
1.6
2.1
mmol/l
1.28
268
1844
2059
19233
1.34
8.19
5.4
5.2
2.6
2.6
mmol/l
1.60
1794
17270
73
350
2.12
8.18
6.8
5.1
1734.9
814.5
iu/ml
—
9
53
491
3802
1.36
8.10
3.4
3.3
0.8
0.8
ug/l
0.14
356
2670
146
882
1.69
8.05
3.3
3.0
1994.5
2691.1
u/ml
0.13
124
751
93
490
1.93
8.04
3.2
3.0
1.8
1.7
mg/l
0.59
79
434
1310
11565
1.27
8.04
3.2
3.2
54.2
54.7
u/l
0.06
1185
10485
150
917
1.67
7.91
1.8
2.6
3.2
3.2
g/l
0.08
118
704
91
484
1.91
7.67
1.8
1.9
10.7
12.4
mg/l
1.28
84
441
131
779
1.72
7.66
1.8
2.4
36.6
37.1
g/l
0.49
108
647
124
727
1.74
7.63
1.9
2.5
0.0
0.0
g/l
0.01
109
655
117
677
1.76
7.54
1.9
2.5
0.0
0.0
g/l
0.00
104
616
367
2744
1.39
7.48
3.2
3.9
244.3
251.2
u/l
0.45
342
2570
118
686
1.75
7.48
1.9
2.5
0.0
0.0
g/l
0.50
104
617
286
2052
1.44
7.36
2.1
2.7
66.0
66.1
g/l
0.07
250
1829
96
531
1.84
7.19
1.9
2.3
3.8
3.6
g/l
0.51
89
496
58
268
2.19
7.17
1.7
1.3
112.2
125.8
u/ml
0.39
14
56
626
5101
1.30
7.14
1.9
1.8
1175.9
1168.5
nmol/l
0.07
475
3767
348
2600
1.39
7.12
3.8
3.8
19.8
23.2
ug/l
0.14
295
2136
1026
8888
1.26
7.10
4.6
4.2
101.1
112.3
ng/l
0.06
780
6798
623
5086
1.30
6.99
1.7
1.6
1.4
1.3
mmol/l
0.38
473
4223
542
4361
1.31
6.76
1.6
1.6
1.9
1.5
mg/l
1.18
418
3396
251
1787
1.45
6.73
2.0
2.1
369.9
382.4
nmol/l
0.44
231
1610
135
839
1.64
6.72
1.9
2.6
0.7
1.2
g/l
0.86
110
709
386
2965
1.35
6.63
1.3
1.3
31.5
39.2
iu/ml
0.55
123
904
108
639
1.72
6.48
1.4
1.5
247.5
274.7
ug/g
0.69
67
379
385
2968
1.35
6.45
8.0
6.1
104.3
104.1
mmol/l
0.19
379
2888
381
2945
1.34
6.27
2.4
2.4
1.8
1.8
%
0.15
334
2565
210
1467
1.47
6.22
9.9
7.9
94.0
93.6
%
0.54
210
1460
263
1916
1.41
6.22
3.3
2.8
4.7
4.5
kpa
0.67
253
1855
259
1885
1.42
6.16
4.2
3.6
98.3
95.5
ng/l
0.17
212
1577
453
3600
1.31
6.14
26.3
29.8
1.3
1.5
inr
0.84
56
485
460
3674
1.31
6.00
1.3
1.2
1.5
1.7
u/ml
0.07
94
904
659
5508
1.26
6.00
2.8
2.8
2779.1
7452.8
umol/l
2.81
521
4624
284
2112
1.39
5.96
2.5
2.1
0.2
0.2
g/l
0.05
262
1950
154
1025
1.53
5.78
2.7
3.2
4.2
4.4
pmol/l
1.08
133
884
73
400
1.85
5.71
3.8
3.4
58.9
59.1
%
0.05
73
400
26
93
2.81
5.56
1.5
1.4
1.9
2.6
%
—
7
17
357
2783
1.33
5.52
7.3
6.5
0.6
1.2
mmol/l
2.20
280
2155
35
148
2.38
5.39
1.4
1.2
95.0
171.0
titre
—
6
29
866
7540
1.22
5.31
4.9
4.6
—
—
—
0
0
123
794
1.58
5.31
1.8
3.3
1.6
1.7
ratio
—
5
62
1976
18662
1.25
5.29
4.7
4.6
4.4
4.5
mmol/l
1.82
1770
16834
33
138
2.41
5.21
1.2
1.3
—
—
—
0
0
125
815
1.56
5.17
1.8
3.3
34.1
75.1
mg/l
1.64
96
678
85
504
1.71
5.13
1.5
1.5
—
—
—
0
0
640
5415
1.24
5.13
4.9
4.6
0.0
0.0
estimate
0.69
287
1724
69
385
1.81
5.13
3.6
3.1
4.6
4.3
e9/l
0.32
69
385
125
818
1.55
5.10
1.8
3.3
47.6
131.3
mg/l
0.66
95
678
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
135
899
1.53
5.09
3.0
2.6
0.3
0.4
u/ml
2.36
71
529
307
2370
1.33
5.08
2.8
3.1
251.2
243.8
ng/l
0.12
280
2163
103
646
1.62
5.03
1.2
1.2
0.6
0.7
u/ml
—
5
56
354
2794
1.31
5.01
7.4
6.4
12.2
11.9
kpa
0.60
337
2644
25
93
2.70
5.00
1.2
1.1
—
—
—
0
0
25
93
2.70
5.00
1.1
1.1
—
—
—
0
0
354
2795
1.31
5.00
7.4
6.4
5.0
5.1
kpa
0.33
336
2641
224
1650
1.39
4.99
3.9
2.9
53.3
59.6
ml/min/173m2
1.32
85
743
172
1218
1.44
4.80
1.5
1.7
1.7
1.5
g/l
1.28
145
1041
10
20
5.01
4.77
9.7
14.7
4.7
5.5
mmol/l
—
10
20
211
2820
0.73
4.74
11.2
8.5
—
—
—
0
0
70
408
1.74
4.53
1.5
1.3
—
—
—
0
0
32
143
2.25
4.40
1.0
1.3
—
—
—
0
0
621
5317
1.22
4.36
2.7
2.4
—
—
—
0
0
82
506
1.64
4.32
1.7
2.1
90.0
88.0
%
0.29
77
479
1945
18465
1.21
4.30
4.7
4.6
1.4
1.5
mmol/l
1.33
1691
16538
83
516
1.63
4.25
1.3
1.2
—
—
—
0
0
64
374
1.73
4.13
1.2
1.2
3.3
5.0
u/ml
—
6
29
352
2847
1.27
4.12
1.3
1.2
21.1
14.9
u/ml
0.57
115
994
19
68
2.81
4.12
1.1
1.2
1.1
1.1
ratio
—
9
20
10
23
4.36
4.08
1.2
1.9
—
—
—
0
0
43
223
1.94
4.06
1.4
1.3
345.2
272.7
pmol/l
0.55
37
161
8
10
8.02
4.06
1.5
2.8
—
—
—
0
0
27
117
2.32
4.01
1.2
1.1
—
—
—
0
0
27
117
2.32
4.01
1.2
1.1
—
—
—
0
0
27
117
2.32
4.01
1.2
1.1
—
—
—
0
0
74
458
1.63
3.88
1.2
1.2
4.9
7.9
u/ml
0.43
13
81
44
237
1.87
3.74
1.4
1.6
—
—
—
0
0
35
174
2.02
3.74
2.9
2.1
631.6
637.9
ml
0.03
29
101
26
116
2.25
3.64
1.2
1.1
—
—
—
0
0
26
116
2.25
3.64
1.2
1.1
—
—
—
0
0
78
501
1.57
3.55
1.6
1.6
—
—
—
0
0
136
981
1.41
3.50
4.9
3.9
51.0
80.6
u/ml
1.53
129
943
90
602
1.51
3.43
1.3
1.2
—
—
—
0
0
71
450
1.59
3.43
1.2
1.2
6.7
4.5
u/ml
—
10
49
93
628
1.50
3.39
2.8
3.4
23.5
25.0
mmol/l
2.56
84
543
186
1423
1.33
3.33
2.4
2.8
10.3
10.6
g/l
0.33
164
1285
257
2057
1.28
3.30
1.4
1.4
—
—
—
0
0
90
609
1.49
3.26
1.3
1.2
—
—
—
0
0
112
792
1.43
3.24
1.6
1.3
—
—
—
0
0
575
5017
1.19
3.21
1.9
1.7
35294558.8
19119899.8
pmol/l
0.32
442
4043
747
6669
1.17
3.16
5.5
5.4
3.4
4.5
ug/l
0.73
630
5893
61
382
1.61
3.12
5.5
1.4
0.8
0.8
nmol/l
0.36
51
310
80
534
1.51
3.11
1.9
1.7
—
—
—
0
0
44
253
1.75
3.09
1.5
1.5
56.8
63.2
%
0.39
22
163
84
568
1.49
3.07
2.2
3.1
8.0
7.9
kpa
0.24
79
524
73
479
1.54
3.07
2.1
2.4
33.5
32.3
umol/l
0.21
57
391
34
181
1.89
3.05
1.3
1.5
—
—
—
0
0
25
119
2.11
3.04
1.3
1.5
—
—
—
0
0
25
119
2.11
3.04
1.3
1.5
—
—
—
0
0
239
1928
1.26
2.90
1.9
2.1
139.1
144.7
ug/g
0.06
188
1492
15
58
2.59
2.87
2.8
2.2
7.0
7.7
mmol/l
—
8
37
82
561
1.48
2.86
1.9
2.2
125.4
127.3
g/l
0.25
63
403
14
53
2.65
2.79
1.1
1.0
2362.8
1657.2
miu/ml
1.30
14
53
739
6648
1.16
2.78
3.6
3.1
6.4
6.9
mmol/l
3.34
584
5474
8
19
4.22
2.67
1.4
1.0
—
—
—
0
0
1860
17833
1.15
2.67
4.2
4.1
1.3
1.3
mmol/l
0.40
1592
15807
27
140
1.94
2.65
1.3
1.4
—
—
—
0
0
189
1501
1.28
2.62
3.3
2.9
125.2
126.8
g/l
0.45
184
1466
603
5364
1.16
2.62
4.5
4.7
22.4
21.9
%
0.31
299
2788
56
847
0.65
2.59
1.6
1.8
—
—
—
0
0
44
268
1.65
2.56
3.6
3.9
—
—
—
0
0
35
200
1.76
2.56
1.1
1.1
—
—
—
0
0
136
1038
1.33
2.54
1.9
1.9
2.8
2.4
ug/l
0.13
117
887
58
379
1.54
2.54
1.3
1.3
—
—
—
0
0
196
1575
1.26
2.49
1.6
1.7
1.6
1.6
%
0.69
159
1321
83
590
1.42
2.42
1.5
1.4
—
—
—
0
0
8
22
3.64
2.36
1.4
1.2
—
—
—
0
0
8
22
3.64
2.36
1.4
1.2
85.1
96.1
%
—
8
22
142
1107
1.30
2.31
2.2
2.1
11.1
12.1
nmol/l
0.68
120
948
10
35
2.86
2.30
1.1
1.0
—
—
—
0
0
756
6898
1.14
2.25
4.7
3.9
18.7
8.8
mg/mmol
2.50
464
4290
19
93
2.05
2.21
1.1
1.0
—
—
—
0
0
110
833
1.33
2.21
1.8
2.1
233.7
524.8
ug/l
2.30
103
784
42
265
1.59
2.17
1.4
1.2
305.4
301.4
u/ml
0.03
33
152
52
347
1.51
2.12
1.5
1.4
—
—
—
0
0
14
62
2.26
2.07
1.0
1.2
—
—
—
0
0
23
124
1.86
2.06
2.8
3.9
—
—
—
0
0
65
457
1.43
2.05
1.4
1.7
—
—
—
0
0
46
302
1.53
2.03
1.6
1.5
—
—
—
0
0
44
286
1.55
2.03
1.4
1.2
—
—
—
0
0
36
223
1.62
2.02
1.3
1.2
75.1
55.1
u/l
0.61
24
148
12
50
2.41
2.02
1.2
1.3
—
—
—
0
0
10
38
2.64
2.01
1.7
1.1
—
—
—
0
0
43
279
1.55
2.00
1.5
1.4
—
—
—
0
0
59
410
1.45
1.99
1.7
1.8
2.2
4.7
iu/l
2.56
16
135
72
521
1.39
1.95
1.4
1.6
3.7
1.3
iu/ml
0.31
16
123
94
712
1.33
1.92
3.7
3.3
0.8
0.8
nmol/l
0.31
81
537
13
58
2.25
1.90
1.3
1.1
—
14.8
u/ml
—
0
9
54
373
1.46
1.89
1.5
1.6
—
—
—
0
0
103
793
1.31
1.89
1.3
1.3
—
—
—
0
0
16
79
2.03
1.85
1.3
1.4
—
—
—
0
0
105
814
1.30
1.84
2.3
2.7
—
—
—
0
0
26
152
1.72
1.83
1.8
1.9
532.6
2997.7
u/l
—
5
50
32
199
1.62
1.80
1.6
1.4
23.7
28.8
%
0.32
15
128
16
80
2.01
1.79
1.3
1.2
—
—
—
0
0
16
297
0.54
1.74
1.4
1.4
—
—
—
0
0
114
905
1.27
1.68
1.4
1.2
228.4
180.3
u/ml
0.29
105
825
19
104
1.83
1.67
1.7
1.3
—
—
—
0
0
6
19
3.16
1.66
1.2
1.3
—
—
—
0
0
54
385
1.41
1.64
1.1
1.1
—
—
—
0
0
28
173
1.62
1.64
1.1
1.1
—
—
—
0
0
11
49
2.25
1.63
1.0
1.1
0.7
0.7
umol/24h
—
5
27
45
312
1.45
1.59
1.5
1.4
—
—
—
0
0
41
280
1.47
1.57
1.5
1.4
—
—
—
0
0
21
122
1.73
1.54
1.2
1.5
1.5
1.1
promille
0.55
14
91
29
184
1.58
1.54
1.3
1.3
—
—
—
0
0
69
520
1.34
1.52
1.6
1.6
—
—
—
0
0
6
21
2.86
1.50
1.2
1.0
—
—
—
0
0
15
79
1.90
1.49
1.9
2.4
848.7
1387.4
u/ml
0.83
15
79
9
37
2.44
1.48
1.2
1.1
—
—
—
0
0
65
492
1.33
1.41
1.6
1.6
—
—
—
0
0
13
67
1.94
1.38
1.5
1.4
—
—
—
0
0
30
198
1.52
1.37
1.1
1.2
3.9
3.8
u/ml
—
7
64
5
17
2.94
1.36
1.0
1.0
—
—
—
0
0
54
401
1.35
1.34
1.1
1.2
—
64.0
—
0
10
16
90
1.78
1.33
2.1
1.4
1.0
1.0
g/l
0.06
16
90
42
300
1.41
1.31
1.5
1.4
80837.4
41493.4
e6/l
0.25
21
175
29
193
1.51
1.29
1.7
1.3
—
—
—
0
0
18
107
1.69
1.25
1.3
1.2
11.9
11.6
mmol/l
—
10
34
18
107
1.69
1.25
1.1
1.1
49.6
41.9
mg/l
0.21
13
91
37
262
1.42
1.22
1.2
1.2
204.6
192.9
miu/ml
—
9
92
177
1531
1.17
1.18
3.7
3.7
5.0
5.2
kpa
1.24
160
1398
5
20
2.50
1.15
2.6
1.6
8.2
12.7
%
—
5
10
5
20
2.50
1.15
1.0
1.0
—
—
—
0
0
0
35
0.00
1.15
0.0
1.3
—
—
—
0
0
40
292
1.38
1.13
1.9
1.5
461.7
292.0
mu/l
1.01
35
260
45
335
1.35
1.13
1.5
1.4
1183.1
1935.8
e6/l
0.84
30
236
19
295
0.64
1.13
1.6
1.4
—
—
—
0
0
7
30
2.34
1.12
1.4
1.6
—
—
—
0
0
19
294
0.64
1.12
1.6
1.4
—
—
—
0
0
12
66
1.82
1.09
1.3
1.3
—
—
—
0
0
69
551
1.26
1.06
1.6
1.6
12041.8
16142.5
e6/l
0.66
49
397
23
153
1.51
1.06
1.7
1.6
—
—
—
0
0
51
392
1.31
1.05
1.2
1.3
—
—
—
0
0
5
22
2.27
1.03
1.2
1.2
—
—
—
0
0
39
289
1.35
1.03
1.3
1.1
—
—
—
0
0
10
53
1.89
1.01
1.1
1.2
0.4
0.3
g/l
—
10
40
20
297
0.67
0.99
1.6
1.4
—
—
—
0
0
20
295
0.68
0.96
1.6
1.4
—
—
—
0
0
9
50
1.80
0.96
1.7
1.5
—
—
—
0
0
34
456
0.74
0.95
1.5
1.7
2.3
4.1
mg/l
0.74
24
348
20
294
0.68
0.95
1.6
1.4
—
—
—
0
0
14
85
1.65
0.94
2.1
2.2
79.8
50.3
umol/l
1.56
14
63
7
37
1.89
0.94
1.3
1.4
80.0
101.0
ng/l
—
7
37
20
293
0.68
0.94
1.6
1.4
—
—
—
0
0
95
798
1.20
0.94
1.1
1.1
—
—
—
0
0
50
391
1.28
0.93
1.6
1.3
68.1
32.1
e6/l
0.23
37
306
26
183
1.42
0.93
1.3
1.3
26.1
10.1
u/l
0.74
21
170
50
392
1.28
0.92
1.6
1.4
1465.2
609.3
e6/l
0.30
40
322
33
244
1.36
0.90
1.5
1.5
—
—
—
0
0
28
202
1.39
0.89
1.0
1.3
—
—
—
0
0
20
135
1.48
0.89
1.5
1.1
—
—
—
0
0
17
112
1.52
0.84
1.8
1.8
—
—
—
0
0
17
112
1.52
0.84
1.5
1.9
663.4
634.9
e6/l
—
7
48
89
1048
0.84
0.84
1.9
2.0
—
—
—
0
0
6
31
1.94
0.84
1.0
1.3
8.1
5.8
nmol/l
—
6
24
66
542
1.22
0.84
3.1
2.3
134.5
74.8
ug/min
0.43
45
308
251
2285
1.11
0.83
2.4
2.5
5.8
6.6
ug/l
0.53
198
1927
20
138
1.45
0.81
1.1
1.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
16
106
1.51
0.78
1.1
1.1
—
—
—
0
0
18
123
1.47
0.77
2.2
2.1
—
—
—
0
0
6
34
1.77
0.76
1.0
1.2
—
—
—
0
0
6
34
1.77
0.76
1.5
1.2
—
—
—
0
0
15
99
1.52
0.75
1.1
1.0
—
—
—
0
0
9
53
1.70
0.75
1.1
1.2
117.3
112.3
%
—
9
45
7
39
1.80
0.72
1.3
1.1
—
—
—
0
0
45
362
1.25
0.71
1.2
1.3
—
—
—
0
0
26
195
1.34
0.69
1.2
1.2
3.7
4.9
u/ml
—
10
100
5
27
1.85
0.68
1.4
1.5
39.6
44.2
umol/l
—
5
27
162
1460
1.12
0.67
3.9
3.6
1.4
2.0
mmol/l
0.87
107
1069
5
28
1.79
0.66
1.0
1.2
1.6
1.7
umol/24h
—
5
28
5
28
1.79
0.66
1.6
2.3
—
—
—
0
0
5
28
1.79
0.66
1.2
1.2
11.0
23.7
u/l
—
5
19
11
70
1.57
0.65
1.8
2.5
—
—
—
0
0
11
70
1.57
0.65
1.8
2.5
—
—
—
0
0
28
215
1.31
0.65
2.0
2.3
1.9
1.9
u/field
—
7
67
17
120
1.42
0.64
1.7
1.8
16.3
14.6
%
—
7
51
84
966
0.87
0.64
1.8
1.8
—
—
—
0
0
36
288
1.25
0.62
1.8
1.8
—
—
—
0
0
8
49
1.63
0.62
1.4
2.0
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
16
114
1.41
0.58
1.4
1.3
0.0
1.3
u/ml
—
10
61
23
175
1.32
0.58
1.1
1.1
—
—
—
0
0
35
282
1.24
0.58
1.2
1.4
—
—
—
0
0
11
73
1.51
0.56
1.2
1.1
—
—
—
0
0
8
55
1.46
0.56
2.0
1.6
—
—
—
0
0
6
37
1.62
0.55
1.0
1.1
—
—
—
0
0
36
294
1.23
0.54
13.4
6.3
8.3
7.5
mmol/l
0.44
31
248
6
39
1.54
0.53
1.2
1.3
—
—
—
0
0
17
223
0.76
0.48
1.0
1.0
—
—
—
0
0
47
401
1.18
0.47
3.7
3.7
1.0
1.3
%
0.55
33
303
17
220
0.77
0.45
1.5
1.2
12175.6
106456.6
e6/l
—
8
146
9
128
0.70
0.43
1.0
1.0
317.2
293.2
mg/l
—
9
112
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
8
59
1.36
0.41
1.9
2.0
32.6
28.4
%
—
8
51
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
7
101
0.69
0.39
1.3
1.0
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
13
98
1.33
0.37
1.5
1.6
—
—
—
0
0
15
190
0.79
0.35
1.1
1.2
8.9
7.7
mmol/l
0.70
15
132
13
101
1.29
0.31
1.1
1.1
—
—
—
0
0
7
54
1.30
0.30
1.6
3.2
—
—
—
0
0
22
184
1.20
0.30
1.8
1.5
—
1696.0
—
0
5
86
932
0.92
0.30
4.8
3.9
24.1
24.9
mmol/l
1.22
77
847
18
148
1.22
0.29
1.2
1.0
—
—
—
0
0
19
159
1.20
0.26
1.1
1.1
0.3
2.5
u/ml
—
8
59
10
78
1.28
0.24
1.3
1.3
37.2
401.8
ug/l
—
5
40
6
81
0.74
0.24
1.0
1.4
—
—
—
0
0
6
81
0.74
0.24
1.0
1.4
—
—
—
0
0
6
81
0.74
0.24
1.0
1.4
—
—
—
0
0
34
303
1.12
0.23
1.1
1.1
—
—
—
0
0
148
1553
0.95
0.23
7.0
6.6
24.1
24.6
mmol/l
0.67
141
1444
5
41
1.22
0.22
4.2
3.2
169.0
196.3
%
—
5
36
22
252
0.87
0.21
3.1
2.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
18
209
0.86
0.21
1.6
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
26
230
1.13
0.20
1.8
1.8
—
—
—
0
0
224
2163
1.04
0.20
1.3
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
9.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
13
155
0.84
0.20
1.4
1.6
—
—
—
0
0
9
113
0.80
0.20
1.0
1.2
—
—
—
0
0
9
115
0.78
0.20
1.0
1.2
—
—
—
0
0
6
50
1.20
0.19
1.3
1.1
—
—
—
0
0
6
50
1.20
0.19
1.5
1.6
9.9
9.1
ug/l
—
6
50
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
6
50
1.20
0.19
1.3
1.1
106.7
102.4
%
—
6
41
47
510
0.92
0.19
4.0
3.9
22.5
28.7
mg/l
1.25
40
332
131
1251
1.05
0.19
3.9
3.2
25.0
25.2
mmol/l
0.32
123
1219
6
53
1.13
0.18
1.5
1.5
—
—
—
0
0
70
744
0.94
0.18
5.7
3.8
3.9
3.9
mmol/l
0.14
65
688
7
62
1.13
0.17
1.1
1.8
21.1
152.2
ug/l
—
7
52
10
82
1.22
0.17
1.4
1.1
—
—
—
0
0
5
67
0.75
0.17
1.0
1.0
—
—
—
0
0
13
111
1.17
0.15
1.1
1.8
3.8
14.7
umol/l
—
5
72
6
76
0.79
0.15
1.0
1.3
—
—
—
0
0
9
79
1.14
0.15
1.2
1.2
—
—
—
0
0
7
87
0.80
0.14
1.1
1.2
7.4
6.3
mmol/l
—
7
81
12
139
0.86
0.14
1.7
1.8
—
—
—
0
0
440
4475
0.98
0.14
4.9
4.8
1.0
1.0
kg/l
0.29
87
700
67
705
0.95
0.14
1.6
1.8
—
—
—
0
0
94
980
0.96
0.13
1.1
1.1
163.8
138.5
iu/ml
0.16
27
348
14
159
0.88
0.13
3.1
1.4
—
—
—
0
0
46
488
0.94
0.12
1.5
1.4
—
—
—
0
0
20
219
0.91
0.11
1.6
1.6
—
—
—
0
0
44
416
1.06
0.11
1.7
1.7
—
—
—
0
0
25
270
0.93
0.10
1.0
1.1
6.0
79.6
iu/ml
—
6
50
13
115
1.13
0.10
1.2
1.4
12.3
15.0
umol/l
1.03
13
104
42
397
1.06
0.10
1.2
1.2
3.9
3.9
mmol/l
0.06
37
370
19
174
1.09
0.09
1.1
1.0
1.4
2.1
u/ml
—
5
57
6
57
1.05
0.08
1.3
1.1
—
—
—
0
0
15
136
1.10
0.08
1.5
1.5
2.6
7.2
u/l
—
5
60
6
58
1.03
0.08
1.3
1.1
—
—
—
0
0
5
62
0.81
0.08
1.0
1.2
—
—
—
0
0
7
84
0.83
0.07
1.1
1.6
—
—
—
0
0
8
92
0.87
0.06
1.0
1.8
—
—
—
0
0
8
92
0.87
0.06
1.0
1.8
—
—
—
0
0
8
94
0.85
0.06
1.0
1.8
—
—
—
0
0
66
640
1.03
0.06
1.5
1.6
—
—
—
0
0
61
629
0.97
0.06
1.5
1.7
—
—
—
0
0
11
120
0.92
0.05
3.5
1.4
—
—
—
0
0
11
120
0.92
0.05
3.5
1.4
—
—
—
0
0
15
160
0.94
0.04
3.0
1.4
—
—
—
0
0
16
151
1.06
0.03
2.8
4.9
28.5
30.4
u/ml
—
5
46
11
118
0.93
0.03
1.3
1.7
—
—
—
0
0
11
118
0.93
0.03
1.3
1.7
—
—
—
0
0
11
118
0.93
0.03
1.3
1.7
—
—
—
0
0
11
118
0.93
0.03
1.3
1.7
—
—
—
0
0
14
132
1.06
0.02
1.5
1.2
2.2
2.1
mmol/l
0.20
14
123
15
142
1.06
0.02
1.2
1.4
—
—
—
0
0
15
142
1.06
0.02
1.2
1.4
—
—
—
0
0
16
152
1.05
0.02
2.5
2.4
—
—
—
0
0
10
107
0.93
0.02
1.3
1.5
—
—
—
0
0
25
256
0.98
0.00
4.0
3.5
61.0
57.3
%
0.30
11
162
89
884
1.01
0.00
4.9
3.6
1.3
1.4
mmol/l
1.20
89
868
12
117
1.03
0.00
1.1
1.3
—
—
—
0
0
19
195
0.97
0.00
1.7
1.6
—
—
—
0
0
19
195
0.97
0.00
1.7
1.6
—
—
—
0
0
19
195
0.97
0.00
1.7
1.6
—
—
—
0
0
12
124
0.97
0.00
4.8
3.5
—
—
—
0
0
5
50
1.00
0.00
1.2
1.1
—
—
—
0
0
9
99
0.91
0.00
6.8
3.1
13.7
13.3
%
—
9
99
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
4.9
—
—
—
0
0
5
53
0.94
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
2.4
—
0
7
0
8
0.00
0.00
0.0
5.0
—
28.6
—
0
8
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_GLAUCNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_GLAUCNAS | 1.308 [1.16, 1.47] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.037 |
During the follow-up period (1.1.1998 — 31.12.2019), 3872 out of 10572 females with H7_GLAUCNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_GLAUCNAS | 1.303 [1.12, 1.52] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 2175 out of 6187 males with H7_GLAUCNAS died.
Mortality risk
Mortality risk for people of age
years, who have H7_GLAUCNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.136% | 0.221% |
| 5 | 0.748% | 1.452% |
| 10 | 1.749% | 3.565% |
| 15 | 3.474% | 6.833% |
| 20 | 5.94% | 11.611% |
Relationships between endpoints
↥Index endpoint: H7_GLAUCNAS – Other and unspecified glaucoma
GWS hits: 4
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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