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Other and unspecified glaucoma

H7_GLAUCNAS

glaucoma: Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H40.8, H40.9
Hospital discharge: ICD-9 3656X|3656C|365[8-9]
Hospital discharge: ICD-8 3752|3759
Hospital discharge: excluded ICD-8 37597
Cause of death: ICD-10 H40.8, H40.9
Cause of death: ICD-9 3656X|3656C|365[8-9]
Cause of death: ICD-8 3752|3759
Cause of death: excluded ICD-8 37597

2 out of 7 registries used, show all original rules.

1967

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Check minimum number of events None

1967

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Include endpoints None

1967

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Remove individuals based on genotype QC

1894

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H7_GLAUCNAS

Control definitions

Control exclude H7_GLAUCOMA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1894 1036 858
Unadjusted prevalence (%) 0.46 0.45 0.47
Mean age at first event (years) 66.10 66.51 65.61

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.24 [2.46, 4.27] 7.9e-17 440
15 years 0.01 1.39 [1.04, 1.84] 2.5e-2 160
5 years 0.00 3.29 [2.56, 4.22] 1.3e-20 159
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_GLAUCNAS – Other and unspecified glaucoma
GWS hits: 4

Survival analyses between endpoints

Plot

before Other and unspecified glaucoma
after Other and unspecified glaucoma

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other and unspecified glaucoma

Endpoint not on priority list, no data to show.