No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
393 |
4. Check minimum number of eventsNone |
393 |
5. Include endpointsNone |
393 |
6. Filter based on genotype QC (FinnGen only) |
381 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Coarctation of the aorta
based on the number of shared cases.
Similar with more cases:
- Congenital malformations of heart and great arteries
- Congenital malformations, deformations and chromosomal abnormalities
- Congenital malformations, deformations and chromosomal abnormalities
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 381 | 156 | 225 |
| Unadjusted period prevalence (%) | 0.08 | 0.06 | 0.10 |
| Median age at first event (years) | 8.54 | 6.39 | 10.03 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 393
- Matched controls
- 3926
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q25.1
ICD-10 Finland
Coarctation of aorta
+∞
307.7
346
*
Q23.11
ICD-10 Finland
Bicuspid aortic valve
118.0
248.4
128
16
74719
ICD-8 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta
+∞
154.6
138
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
10.8
128.9
242
507
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
10.9
124.6
190
310
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
21.8
121.6
98
59
201
Kela drug reimbursment
Chronic cardiac insufficiency
22.6
114.6
90
51
I35.0
ICD-10 Finland
Aortic (valve) stenosis
22.7
105.6
82
45
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
58.8
105.4
60
12
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
16.0
104.1
99
81
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
13.1
103.9
115
120
B01AA03
ATC
warfarin; systemic
9.7
92.4
134
199
7471A
ICD-9 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta[COARCTATIO AORTAE]
+∞
90.1
83
*
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
51.9
85.7
50
11
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
38.9
81.4
51
15
61
HP
Catheterization and pressure measurement of the left side of the heart
45.4
79.8
48
12
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
22.2
70.5
54
28
XF402
NOMESCO Finland
ECG with work load test
8.9
67.6
98
142
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
8.2
62.7
97
151
XFE00
NOMESCO Finland
Epicardial ultrasonography
20.6
62.1
49
27
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
12.5
60.8
64
60
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
17.5
56.3
48
31
XF600
NOMESCO Finland
Bloodpressure measurement
6.7
51.1
95
178
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.2
48.3
128
331
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.9
48.0
85
151
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
14.9
47.5
44
33
C01AA05
ATC
digoxin; systemic
11.1
45.4
51
52
FM2CE, ,
NOMESCO Finland
9.2
45.1
59
74
XF400
NOMESCO Finland
ECG with 12 standard connections
4.7
43.6
135
393
C03CA01
ATC
furosemide; systemic
4.8
42.6
126
353
C03DA01
ATC
spironolactone; oral
6.4
42.6
80
150
Q21.10
ICD-10 Finland
Persistent ostium secundum
13.4
38.9
38
31
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.8
38.2
227
1031
XF404
NOMESCO Finland
Ambulatory ECG
5.9
37.4
76
153
205
Kela drug reimbursment
Chronic hypertension
4.6
37.1
112
316
WX872
NOMESCO Finland
Intensive care
9.0
36.6
48
60
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
46.8
34.8
42
10
Q25.40
ICD-10 Finland
Aortic hypoplasia
+∞
33.8
32
*
31
HP
Congenital heart failure surgery
78.8
32.4
36
5
Q23.0
ICD-10 Finland
Congenital stenosis of aortic valve
95.8
32.3
35
*
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
123.6
32.2
34
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
4.2
32.1
108
327
ZXE20
NOMESCO Finland
More than three and less than five hours
4.3
31.0
96
273
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
56.3
30.9
36
7
Q25.0
ICD-10 Finland
Patent ductus arteriosus
31.6
30.5
40
14
ZXE30
NOMESCO Finland
More than five and less than seven hours
6.2
29.8
55
100
5513
FHL
Coarctation resection, plastic or bypass
+∞
29.5
28
*
TPH07
NOMESCO Finland
Cathetrisation of artery
4.5
28.5
80
210
PD5DG
NOMESCO Finland
Very extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
+∞
27.4
26
*
C07AB07
ATC
bisoprolol; oral
3.1
26.2
183
865
Q25.3
ICD-10 Finland
Stenosis of aorta
133.0
23.9
25
*
C07AB02
ATC
metoprolol; systemic
3.9
23.2
81
248
FDJ00
NOMESCO Finland
End to end reconstruction of aorta for coarctation
+∞
23.1
22
*
FDJ42
NOMESCO Finland
Percutaneous transluminal angioplasty of thoracic aorta in coarctation
+∞
23.1
22
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.9
23.0
186
937
62
HP
Catheterization and pressure measurement of the right side of the heart
88.8
22.9
25
*
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
48.0
22.6
27
6
I50.9
ICD-10 Finland
Heart failure, unspecified
4.9
22.2
53
121
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
66.4
22.1
25
*
K83
ICPC
Heart valve disease NOS
85.0
21.9
24
*
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
20.2
20.3
30
16
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
6.3
20.0
35
60
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
24.0
19.3
27
12
WX408
NOMESCO Finland
General anesthesy, balanced
2.7
19.3
145
691
81
HP
Angiography of the heart and coronary arteries
6.8
18.6
30
47
I48
ICD-10 Finland
Atrial fibrillation and flutter
3.5
18.5
71
230
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
46.4
18.4
22
5
Z2221
NOMESCO Finland
Medical doctor
2.6
17.8
145
715
TFP20
NOMESCO Finland
Cardiodefibrillation
5.1
17.7
39
83
PD5BD
NOMESCO Finland
Extensive CT of aorta
21.2
16.6
24
12
Q24.4
ICD-10 Finland
Congenital subaortic stenosis
177.0
16.6
17
*
WX882
NOMESCO Finland
High dependency care
4.2
16.2
46
120
Q23.10
ICD-10 Finland
Congenital insufficiency of aortic valve
35.0
15.9
20
6
Q20.3
ICD-10 Finland
Discordant ventriculoarterial connection
27.6
15.7
21
8
74639
ICD-8 Finland
Congenital anomalies of heart, Defectus septi ventriculorum
+∞
15.7
15
*
FC1AC
NOMESCO Finland
Angiography of thoracal aortta
88.6
15.7
17
*
XF622
NOMESCO Finland
Measurement of minute volume of heart
30.0
15.3
20
7
XF640, ,
NOMESCO Finland
12.5
15.3
27
23
C09AA02
ATC
enalapril; systemic
3.2
15.1
67
236
ZXE40
NOMESCO Finland
More than seven and less than nine hours
6.1
15.1
27
47
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
22.1
14.8
21
10
74709
ICD-8 Finland
Other congenital anomalies of circulatory system, Patent ductus arteriosus
83.2
14.7
16
*
FCA50
NOMESCO Finland
Resection and reconstruction of ascending aorta using tube graft
+∞
13.6
13
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
13.5
154
863
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
41.6
13.2
16
*
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
13.6
13.1
22
17
FCA60
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of composite graft with mechanical valve prosthesis
51.8
12.9
15
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
4.4
12.7
33
80
FCC45
NOMESCO Finland
Percutaneous insertion of stent into descending aorta
+∞
12.6
12
*
PD5BG
NOMESCO Finland
MRI examination of thoracal and abdominal aortta with high intensity magnet
134.0
12.5
13
*
C01BD01
ATC
amiodarone; systemic
10.5
12.1
23
23
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
27.7
12.1
16
6
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.4
12.1
111
563
FXA13
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and exclusive cerebral perfusion
66.9
11.7
13
*
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
9.7
11.6
23
25
74673
ICD-8 Finland
Congenital anomalies of heart, Stenosis valvulae aortae
+∞
11.5
11
*
Q25.48
ICD-10 Finland
Other congenital malformations of the aorta
123.4
11.5
12
*
Z98.8
ICD-10 Finland
Other specified postsurgical states
11.0
11.4
21
20
AN1
HP
Coronary angiography
3.7
11.1
37
108
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
5.0
11.1
24
50
PD5AD
NOMESCO Finland
CT of aorta
9.2
10.9
22
25
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
11.0
10.9
20
19
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
4.8
10.6
24
52
PC1BD
NOMESCO Finland
Extensive CT of thoracic aorta
112.8
10.5
11
*
Q25.21
ICD-10 Finland
Interrupted aortic arch
+∞
10.5
10
*
FMD40
NOMESCO Finland
Replacement of aortic root using pulmonary autograft and reimplantation of coronary arteries (Ross)
+∞
10.5
10
*
7463A
ICD-9 Finland
Other congenital anomalies of heart, Congenital stenosis of aortic valve[STENOSIS VALVULAE AORTAE CONGENITA]
+∞
10.5
10
*
Q23.4
ICD-10 Finland
Hypoplastic left heart syndrome
33.5
10.4
13
*
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
7.8
10.3
23
31
I44.2
ICD-10 Finland
Atrioventricular block, complete
10.4
10.1
19
19
FHB50
NOMESCO Finland
Transatrial closure of VSD using patch
26.8
9.9
13
5
B01AB05
ATC
enoxaparin; parenteral
2.2
9.9
101
532
C08CA01
ATC
amlodipine; oral
2.1
9.8
113
623
WX892
NOMESCO Finland
Monitored bed care
3.1
9.7
42
145
WX402
NOMESCO Finland
General anaesthesia
2.1
9.7
110
603
FDF05
NOMESCO Finland
Percutaneous transluminal occlusion of aorto-pulmonary collaterals
56.4
9.7
11
*
ZXD05
NOMESCO Finland
Urgent procedure
2.1
9.7
125
720
AJ1
HP
Reconstruction of the aortic base, eg composite graft, incl. valve saving operation
102.3
9.5
10
*
AP3
HP
Catheterization of the right and left side of the heart
102.3
9.5
10
*
AB1
HP
AVR mechanical
102.3
9.5
10
*
Q20.1
ICD-10 Finland
Double outlet right ventricle
102.3
9.5
10
*
FCC50
NOMESCO Finland
Resection and reconstruction of descending aorta using tube graft
+∞
9.4
9
*
FC1BC
NOMESCO Finland
Extensive angiography of thoracal aortta
+∞
9.4
9
*
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.6
9.4
60
256
Z3231
NOMESCO Finland
Registered nurse
2.0
9.3
139
841
G04BE03
ATC
sildenafil; oral
11.8
9.1
16
14
RS224, ,
NOMESCO Finland
10.4
9.1
17
17
ZXE00
NOMESCO Finland
One hour or less
1.9
9.1
167
1084
Q21.19
ICD-10 Finland
Atrial septal defect NOS
37.6
9.1
11
*
FDA00
NOMESCO Finland
Aortoplasty and aorto-pulmonary shunt for HLHS
37.6
9.1
11
*
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
37.6
9.1
11
*
C07AG02
ATC
carvedilol; oral
4.4
9.0
23
55
Q21.0
ICD-10 Finland
Ventricular septal defect
24.7
9.0
12
5
ZX120
NOMESCO Finland
Intravenous
2.9
8.9
45
170
C07AA07
ATC
sotalol; systemic
7.5
8.8
20
28
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
14.4
8.7
14
10
TFC10
NOMESCO Finland
Catheterisation of left atrium or ventricle
16.7
8.6
13
8
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
4.3
8.6
22
53
WX704
NOMESCO Finland
Intubation
3.1
8.5
37
128
Q20.48
ICD-10 Finland
Single ventricle
28.2
8.5
11
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
8.5
88
463
5255
FHL
Deep hypothermia (<20 °) with cardiopulmonary resuscitation
91.9
8.4
9
*
TFC20
NOMESCO Finland
Catheterisation of both sides of heart
91.9
8.4
9
*
21
HP
Aortic Valve Replacement (AVR)
91.9
8.4
9
*
FLE96
NOMESCO Finland
Other repair of outlet obstruction of left ventricle
91.9
8.4
9
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.3
8.4
32
102
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
3.5
8.4
29
87
7454B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM SIMPLEX]
+∞
8.4
8
*
PD5CD
NOMESCO Finland
Very extensive CT angiography of aorta
+∞
8.4
8
*
PD5CM
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aorta with 3 Tesla magnet
+∞
8.4
8
*
5609
FHL
Other measure in this category
+∞
8.4
8
*
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
9.7
8.3
16
17
C09AA05
ATC
ramipril; oral
2.3
8.3
73
359
207
Kela drug reimbursment
Chronic arrhythmias
2.9
8.2
41
154
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.2
8.1
73
363
K78
ICPC
Atrial fibrillation/flutter
4.0
8.1
23
60
R4110
NOMESCO Finland
Physiotherapy
1.9
8.0
121
730
FBE10
NOMESCO Finland
Expansion or reconstruction of pulmonary artery using patch
25.5
7.6
10
*
602
Kela drug reimbursment
Children's severe malnutrition
4.4
7.5
19
45
74659
ICD-8 Finland
Congenital anomalies of heart, Maleformatio valvulae mitralis
+∞
7.3
7
*
Q25.9
ICD-10 Finland
Congenital malformation of great arteries, unspecified
+∞
7.3
7
*
Q23.20
ICD-10 Finland
Congenital mitral stenosis
+∞
7.3
7
*
FMA20
NOMESCO Finland
Plastic repair of aortic valve for stenosis
+∞
7.3
7
*
M01AE01
ATC
ibuprofen; systemic, rectal
0.6
7.3
232
2835
I50.1
ICD-10 Finland
Left ventricular failure
4.6
7.2
17
38
I50.0
ICD-10 Finland
Congestive heart failure
4.2
7.1
19
47
J01CA04
ATC
amoxicillin; systemic
2.3
7.1
345
2971
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.9
7.0
121
758
I10
ICD-10 Finland
Essential (primary) hypertension
1.8
6.9
155
1051
ZXX09
NOMESCO Finland
Extent of procedure, more than 8 units
40.7
6.8
8
*
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
17.0
6.8
10
6
TPH05
NOMESCO Finland
Open cannulation of peripheral vein
22.9
6.7
9
*
TFP00
NOMESCO Finland
Temporary use of transvenous or epicardial pacemaker
12.5
6.6
11
9
WZC30
NOMESCO Finland
Teaching
2.2
6.6
63
320
R50.9
ICD-10 Finland
Fever, unspecified
2.0
6.5
83
468
74699
ICD-8 Finland
Congenital anomalies of heart, Unspecified anomalies of heart
70.9
6.4
7
*
I15.8
ICD-10 Finland
Other secondary hypertension
14.6
6.4
10
7
C08CA02
ATC
felodipine; oral
3.2
6.4
25
81
J21.0
ICD-10 Finland
Acute bronchiolitis due to respiratory syncytial virus
4.2
6.4
17
42
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
2.7
6.4
34
132
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
8.4
6.4
13
16
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
18.4
6.3
9
5
FDH96
NOMESCO Finland
Other operation for interrupted or hypoplastic aortic arch
+∞
6.3
6
*
1CX08, ,
NOMESCO Finland
+∞
6.3
6
*
FDH10
NOMESCO Finland
Reconstruction of interrupted or hypoplastic aortic arch using patch
+∞
6.3
6
*
Q20.00
ICD-10 Finland
Common arterial trunk
+∞
6.3
6
*
G25.1
ICD-10 Finland
Drug-induced tremor
+∞
6.3
6
*
FDJ30
NOMESCO Finland
Reconstruction of aorta for coarctation using tube graft
+∞
6.3
6
*
74729
ICD-8 Finland
Other congenital anomalies of circulatory system, Maleformationes aortae aliae
+∞
6.3
6
*
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.6
6.2
20
57
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
6.1
81
463
XQ903
NOMESCO Finland
Production of other scan or drawing
12.8
6.1
10
8
C07AB03
ATC
atenolol; systemic
3.7
6.1
19
53
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
8.8
6.1
12
14
C09CA03
ATC
valsartan; oral
2.9
6.1
29
106
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.4
6.1
43
192
UGC02
NOMESCO Finland
Rigid bronchoscopy
10.2
6.1
11
11
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
238
597
8.56
103.12
7.1
3.7
1334.91
903.97
ng/l
0.99
222
504
121
171
9.77
86.47
4.7
3.3
171.69
174.23
ng/l
0.02
107
155
235
1071
3.96
39.77
39.9
9.9
1.98
1.19
inr
9.32
56
331
100
333
3.68
25.47
9.4
12.2
7.22
6.50
mmol/l
0.45
100
321
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
40
75
5.82
20.86
34.8
8.9
0.36
0.33
u/ml
0.25
24
46
113
467
2.99
19.72
7.2
3.7
1895.60
654.59
ng/l
1.92
95
326
147
710
2.71
19.00
3.3
2.7
—
—
—
0
0
26
41
6.71
16.01
4.2
5.1
79.19
100.59
%
2.45
26
41
88
367
2.80
14.71
2.5
2.8
22.11
24.23
%
0.77
75
329
105
485
2.59
14.31
11.4
7.5
0.83
0.82
mmol/l
0.45
105
464
54
186
3.20
12.58
23.1
7.2
86.31
92.51
%
0.93
54
186
204
1315
2.14
12.33
3.8
2.8
—
—
—
0
0
143
835
2.12
10.87
10.6
5.7
77.78
90.75
%
6.68
143
826
74
334
2.49
10.33
12.0
9.7
106.09
104.66
mmol/l
1.66
74
334
245
1763
2.03
10.25
12.2
6.3
6.28
6.49
mmol/l
1.03
231
1644
62
261
2.63
9.98
29.4
11.2
14.34
13.27
kpa
0.68
62
251
62
261
2.63
9.98
29.5
11.3
5.22
5.22
kpa
0.00
62
249
16
12
13.82
9.74
5.1
5.5
—
—
—
0
0
61
260
2.59
9.56
30.0
11.4
0.89
0.70
mmol/l
0.14
55
212
364
3121
3.24
9.30
24.1
13.9
139.54
139.58
mmol/l
0.15
359
3049
207
1441
1.92
9.13
9.5
7.4
19.34
15.39
umol/l
1.11
194
1371
364
3128
3.20
9.12
23.8
13.9
3.99
3.97
mmol/l
0.55
358
3047
37
131
3.01
8.19
5.9
10.3
0.71
0.62
%
0.90
37
131
38
137
2.96
8.15
5.8
9.9
1.22
1.39
%
0.53
38
137
60
276
2.38
7.96
27.5
12.4
1.21
1.40
mmol/l
1.19
60
269
40
153
2.79
7.71
4.8
7.2
185.37
166.44
%
0.88
40
153
50
215
2.52
7.66
24.6
11.8
116.64
125.00
g/l
1.89
50
208
119
736
1.88
7.19
3.1
2.2
455.38
345.31
u/l
0.41
114
705
116
717
1.87
6.99
2.3
2.8
2.77
2.89
mg/l
0.28
103
622
135
881
1.81
6.81
3.8
3.0
57.20
35.75
ng/l
0.42
88
532
163
1136
1.74
6.49
8.2
6.7
35.86
36.85
g/l
1.15
156
1088
91
541
1.89
6.10
12.7
9.0
1.21
1.20
mmol/l
0.08
91
513
23
77
3.11
5.62
2.1
1.6
—
—
—
0
0
11
14
8.04
5.37
1.8
3.0
—
—
—
0
0
25
93
2.80
5.10
1.6
1.8
1.43
1.30
g/l
0.15
15
82
76
451
1.85
5.07
6.8
9.1
1.21
1.34
mmol/l
0.13
63
360
17
52
3.37
4.79
2.6
3.2
17.46
17.00
%
—
9
33
298
2552
1.69
4.69
14.1
10.3
90.31
90.87
ml/min/173m2
0.16
260
2036
179
1360
1.58
4.67
3.2
3.2
101.23
103.19
ug/l
0.06
170
1285
17
55
3.18
4.40
2.6
3.7
—
—
—
0
0
17
57
3.07
4.17
1.7
1.5
—
—
—
0
0
236
1940
1.54
4.14
12.6
11.0
4.08
3.82
e9/l
0.93
212
1657
28
126
2.31
3.92
20.2
11.6
24.14
24.81
mmol/l
0.36
28
118
68
421
1.74
3.91
2.0
1.9
—
—
—
0
0
181
1432
1.49
3.65
13.0
9.9
1.20
1.22
mmol/l
3.70
164
1272
38
202
1.97
3.53
2.6
2.6
71.35
73.18
ml/min/173m2
0.11
20
83
254
2170
1.48
3.35
7.6
7.2
91.52
90.88
u/l
0.05
244
2059
21
90
2.41
3.30
6.9
2.5
692.68
328.38
ug/l
0.70
21
84
64
410
1.67
3.25
11.6
8.7
5.06
5.06
kpa
0.03
64
397
63
403
1.67
3.21
11.6
8.8
1.94
1.12
mmol/l
2.44
54
302
20
85
2.42
3.20
11.4
11.3
1.50
1.65
%
0.46
20
77
52
316
1.74
3.19
12.2
9.7
9.68
9.48
kpa
0.36
52
306
207
1713
1.44
3.15
9.1
8.2
26.28
31.56
%
8.34
199
1645
348
3202
1.75
3.15
18.3
12.3
29.92
21.76
mg/l
3.73
290
2386
204
1688
1.43
3.08
9.1
8.0
57.68
53.26
%
5.81
196
1618
67
446
1.60
2.92
22.5
13.3
25.16
24.74
mmol/l
0.72
67
446
63
422
1.59
2.68
1.6
1.7
502.85
448.27
pmol/l
0.58
53
378
51
325
1.65
2.65
1.8
1.8
—
—
—
0
0
135
1065
1.41
2.55
3.5
3.7
—
—
—
0
0
54
353
1.61
2.54
11.3
8.3
25.15
24.36
mmol/l
2.26
54
347
17
75
2.32
2.54
2.1
1.9
—
—
—
0
0
18
84
2.20
2.38
1.2
1.1
—
—
—
0
0
50
328
1.60
2.33
1.9
1.9
—
—
—
0
0
14
59
2.42
2.31
2.8
3.6
0.27
0.18
e9/l
—
9
41
111
860
1.40
2.30
3.8
2.8
62.09
60.64
u/l
0.11
102
806
6
13
4.66
2.27
2.3
1.2
—
—
—
0
0
17
79
2.20
2.27
2.1
2.1
—
—
—
0
0
97
737
1.42
2.24
3.5
3.4
0.00
0.02
estimate
0.88
32
268
8
24
3.38
2.19
3.4
2.6
107.00
106.29
mmol/l
—
8
24
86
645
1.42
2.13
6.7
3.2
2.48
1.20
mg/l
1.52
57
484
380
3655
2.17
2.07
33.2
18.5
39.96
40.80
%
2.07
366
3490
5
10
5.04
2.07
1.0
1.2
—
—
—
0
0
16
76
2.15
2.05
1.3
1.4
—
—
—
0
0
16
76
2.15
2.05
1.3
1.4
—
—
—
0
0
9
34
2.68
1.87
4.2
4.0
25.44
25.94
umol/l
—
9
34
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
7
23
3.08
1.80
1.4
2.0
171.29
131.09
%
—
7
23
11
47
2.38
1.79
18.2
16.5
104.27
104.97
mmol/l
0.24
11
40
6
20
3.03
1.58
5.0
6.3
—
—
—
0
0
13
64
2.06
1.55
2.0
2.0
—
—
—
0
0
13
64
2.06
1.55
2.0
2.0
—
—
—
0
0
6
21
2.88
1.51
1.2
1.0
—
—
—
0
0
50
667
0.71
1.44
3.1
3.5
22.04
21.29
%
0.11
23
253
5
16
3.15
1.44
2.4
3.7
—
—
—
0
0
37
259
1.47
1.35
9.9
6.5
—
—
—
0
0
28
185
1.55
1.33
1.8
1.6
—
—
—
0
0
32
455
0.68
1.32
1.3
1.2
15.22
6.64
u/ml
—
10
175
34
236
1.48
1.29
3.4
3.2
—
—
—
0
0
12
62
1.96
1.28
3.8
3.6
4.88
4.93
kpa
0.17
12
62
14
77
1.85
1.26
1.9
2.1
—
—
—
0
0
14
77
1.85
1.26
1.9
2.1
—
—
—
0
0
14
77
1.85
1.26
1.1
2.0
—
—
—
0
0
30
204
1.51
1.26
4.3
4.7
18.69
27.18
ug/l
0.14
22
167
5
19
2.65
1.22
1.4
1.3
—
—
—
0
0
17
101
1.71
1.21
1.8
2.0
—
—
—
0
0
17
101
1.71
1.21
1.8
2.0
—
—
—
0
0
165
1455
1.23
1.21
3.2
3.3
0.00
0.00
estimate
-0.00
34
258
163
1438
1.23
1.18
4.3
4.7
0.00
0.00
estimate
0.50
33
277
0
33
0.00
1.16
0.0
3.2
—
2.68
—
0
26
5
20
2.52
1.15
3.8
9.9
2.48
1.84
mg/l
—
5
15
64
507
1.31
1.15
1.4
1.4
20.74
21.28
nmol/l
0.13
58
433
5
111
0.44
1.15
1.2
1.5
—
—
—
0
0
22
144
1.56
1.11
1.5
1.5
—
—
—
0
0
7
31
2.28
1.11
1.1
1.2
—
—
—
0
0
7
31
2.28
1.11
1.1
1.2
—
—
—
0
0
7
31
2.28
1.11
1.1
1.2
—
—
—
0
0
7
31
2.28
1.11
1.1
1.2
—
—
—
0
0
7
31
2.28
1.11
1.1
1.2
—
—
—
0
0
296
2790
1.24
1.07
4.2
3.9
4.40
4.64
mmol/l
4.15
284
2649
346
3326
1.33
1.04
12.2
9.6
29.62
28.43
u/l
0.37
336
3237
11
60
1.86
1.03
1.2
2.0
—
—
—
0
0
23
155
1.51
1.03
1.6
1.3
—
—
—
0
0
5
107
0.46
1.02
5.2
3.9
26.20
23.81
nmol/l
—
5
102
232
2140
1.20
1.02
4.4
3.7
49.74
42.84
u/l
0.70
220
2053
23
157
1.49
0.98
2.0
2.6
9035.00
2282.34
u/l
0.43
12
53
0
31
0.00
0.96
0.0
1.2
—
—
—
0
0
11
62
1.79
0.95
1.5
1.8
—
—
—
0
0
161
1445
1.19
0.94
3.4
3.3
0.00
0.00
estimate
0.50
37
281
246
2293
1.19
0.92
3.6
3.7
15.11
14.56
pmol/l
2.75
231
2130
71
846
0.80
0.91
3.3
3.9
1.70
2.07
ug/l
0.37
65
767
32
237
1.38
0.91
2.8
2.0
—
—
—
0
0
5
105
0.47
0.90
1.2
1.4
—
—
—
0
0
5
105
0.47
0.90
1.2
1.4
—
—
—
0
0
5
105
0.47
0.90
1.2
1.4
—
—
—
0
0
5
105
0.47
0.90
1.2
1.4
—
—
—
0
0
18
121
1.51
0.84
1.6
1.7
—
—
—
0
0
8
47
1.71
0.81
1.4
2.0
—
—
—
0
0
122
1082
1.18
0.80
3.6
3.2
—
—
—
0
0
101
881
1.20
0.80
3.2
3.5
0.31
0.28
e6/l
0.11
82
647
14
210
0.65
0.79
1.4
1.2
—
—
—
0
0
0
26
0.00
0.78
0.0
2.8
—
—
—
0
0
19
132
1.46
0.77
1.8
1.9
278.55
171.74
u/ml
0.56
11
66
23
310
0.73
0.75
1.7
1.6
—
—
—
0
0
289
2755
1.18
0.74
4.3
4.3
1.93
1.89
mu/l
0.26
269
2565
40
495
0.79
0.72
2.4
2.6
1.36
0.68
ug/l
0.60
21
277
7
41
1.72
0.70
1.6
2.5
—
—
—
0
0
19
136
1.42
0.68
1.8
1.9
—
—
—
0
0
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
11
71
1.56
0.62
3.8
2.6
—
—
—
0
0
40
327
1.25
0.61
1.4
1.6
1193.50
1226.51
nmol/l
0.08
34
251
35
282
1.26
0.60
2.7
2.0
—
—
—
0
0
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
77
675
1.17
0.59
3.4
3.5
358.92
3859.79
umol/l
1.70
72
607
292
2811
1.15
0.55
4.5
4.2
2.68
2.82
mmol/l
2.10
280
2641
9
60
1.51
0.54
1.4
1.8
—
—
—
0
0
17
125
1.37
0.54
2.5
1.8
—
—
—
0
0
288
2773
1.14
0.53
4.1
3.8
1.35
1.40
mmol/l
1.28
277
2608
30
367
0.80
0.52
3.2
2.5
371.13
352.12
nmol/l
0.26
30
346
9
65
1.39
0.51
1.9
4.6
64.78
55.05
%
—
9
65
87
962
0.88
0.49
1.4
1.6
1.23
2.29
u/ml
0.75
23
209
87
962
0.88
0.49
1.7
1.8
—
—
—
0
0
21
266
0.78
0.49
1.0
1.1
—
—
—
0
0
7
46
1.53
0.48
1.6
1.7
—
—
—
0
0
7
46
1.53
0.48
1.3
1.3
—
—
—
0
0
7
47
1.50
0.47
1.3
1.3
—
—
—
0
0
12
85
1.42
0.47
1.8
2.5
—
—
—
0
0
278
2680
1.12
0.47
3.9
3.6
1.33
1.30
mmol/l
0.29
266
2513
16
120
1.35
0.46
2.6
1.8
—
86.65
—
0
15
5
85
0.58
0.45
1.0
1.2
—
—
—
0
0
74
663
1.14
0.44
3.6
3.2
1.02
1.02
kg/l
0.04
13
91
17
131
1.31
0.42
2.2
3.7
0.06
0.06
e6/l
0.04
17
125
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
16
123
1.31
0.41
1.3
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
2.1
—
19.61
—
0
7
0
17
0.00
0.40
0.0
3.0
—
160.01
—
0
17
257
2655
0.90
0.40
3.5
3.6
—
—
—
0
0
0
18
0.00
0.40
0.0
3.9
—
81.71
—
0
18
10
71
1.42
0.39
1.5
1.6
—
—
—
0
0
12
159
0.75
0.39
1.6
1.9
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.6
—
—
—
0
0
11
80
1.38
0.38
1.7
1.3
—
—
—
0
0
6
41
1.47
0.36
2.5
1.7
12.50
13.00
%
—
6
41
10
134
0.74
0.35
1.4
1.3
—
—
—
0
0
6
44
1.37
0.34
1.8
1.3
—
—
—
0
0
15
188
0.79
0.34
1.4
1.5
—
—
—
0
0
42
473
0.87
0.32
1.2
1.2
19.60
27.34
iu/ml
—
10
143
230
2219
1.09
0.32
4.5
4.1
10.59
9.02
mm/h
0.82
215
2083
95
882
1.10
0.32
3.8
3.3
2.38
2.37
mmol/l
0.28
90
800
7
52
1.35
0.31
1.6
1.7
—
—
—
0
0
11
84
1.32
0.30
1.4
1.5
258.33
308.44
ug/g
—
6
44
95
887
1.09
0.29
2.0
1.7
90.92
95.15
pmol/l
0.49
63
455
7
57
1.23
0.29
9.0
1.7
9.51
9.73
g/l
—
7
51
7
57
1.23
0.29
4.0
1.6
—
—
—
0
0
8
62
1.29
0.28
1.3
1.2
—
—
—
0
0
8
65
1.23
0.27
1.6
1.4
—
—
—
0
0
61
559
1.11
0.27
2.4
3.3
0.81
0.67
e6/l
0.27
36
310
5
72
0.69
0.26
2.2
1.1
—
62.41
—
0
22
21
243
0.86
0.24
1.6
1.3
98.93
146.72
iu/ml
—
8
92
274
2680
1.07
0.23
4.0
3.7
5.75
5.80
mmol/l
0.41
257
2485
5
42
1.19
0.21
3.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
2.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
361.00
—
0
6
0
12
0.00
0.21
0.0
3.8
—
25.08
—
0
12
0
12
0.00
0.21
0.0
1.1
—
32.56
—
0
12
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
95.51
—
0
12
0
12
0.00
0.21
0.0
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
63
672
0.92
0.20
3.9
4.0
2.91
34.89
mg/mmol
0.72
40
456
6
53
1.13
0.18
10.3
1.6
41.28
39.33
g/l
—
6
48
50
536
0.92
0.18
2.3
2.1
—
—
—
0
0
7
59
1.19
0.18
9.0
1.8
2.94
2.78
g/l
—
7
54
7
63
1.11
0.17
9.0
1.7
3.24
3.48
g/l
—
7
58
7
63
1.11
0.17
9.0
1.7
7.26
7.16
g/l
—
7
58
7
63
1.11
0.17
9.0
1.7
—
—
—
0
0
5
69
0.72
0.17
1.0
1.0
3.10
3.12
kpa
—
5
59
5
70
0.71
0.17
1.0
1.0
6.38
7.43
kpa
—
5
60
6
79
0.76
0.15
1.0
1.4
—
—
—
0
0
254
2497
1.05
0.14
4.8
4.9
37.13
39.01
mmol/mol
3.82
241
2369
8
99
0.80
0.14
1.3
1.7
165.38
243.84
pmol/l
—
8
93
56
537
1.05
0.09
2.4
3.5
1.65
1.66
e6/l
0.01
33
290
6
54
1.11
0.09
1.7
1.1
—
—
—
0
0
6
56
1.07
0.08
10.3
2.0
0.42
0.88
g/l
—
6
51
5
64
0.78
0.08
1.0
1.3
—
—
—
0
0
6
72
0.83
0.07
1.2
1.4
—
—
—
0
0
35
367
0.95
0.07
1.3
1.4
—
—
—
0
0
16
147
1.09
0.07
1.8
1.6
—
—
—
0
0
8
93
0.86
0.07
1.6
1.5
—
0.05
—
0
17
9
101
0.89
0.06
1.8
1.8
—
—
—
0
0
119
1202
0.98
0.03
3.0
2.9
80.65
71.89
nmol/l
2.63
110
1112
58
588
0.98
0.01
2.3
2.2
—
—
—
0
0
11
114
0.96
0.00
1.3
1.1
—
—
—
0
0
11
114
0.96
0.00
1.3
1.1
—
—
—
0
0
14
136
1.03
0.00
1.4
1.4
—
—
—
0
0
14
140
1.00
0.00
1.1
1.2
—
—
—
0
0
77
773
0.99
0.00
1.8
1.8
1.52
1.40
mmol/l
0.52
71
679
16
155
1.03
0.00
1.2
1.3
0.20
3.14
u/ml
2.73
11
109
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
11.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
68
0.88
-0.00
6.7
4.1
332.50
380.98
umol/l
—
6
61
8
79
1.01
-0.00
1.8
1.7
—
—
—
0
0
5
56
0.89
-0.00
1.2
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
4.56
—
0
5
5
50
1.00
-0.00
1.4
1.1
—
—
—
0
0
9
90
1.00
-0.00
1.4
1.6
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_COARCTATION_OF_THE_AORTA – Coarctation of the aorta
GWS hits: 1
This endpoint is excluded (different definition than used in FinnGen).