meibomian cyst: An eyelid cyst caused by the blockage of a meibomian gland.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
4883 |
4. Check minimum number of eventsNone |
4883 |
5. Include endpointsNone |
4883 |
6. Filter based on genotype QC (FinnGen only) |
4883 |
Control definitions (FinnGen only)
- Control exclude
- H7_LIDLACRIMALORBIT
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H00
- Name in latin
- Chalazion
Similar endpoints
↥List of similar endpoints to
Chalazion
based on the number of shared cases.
Similar with more cases:
- Disorders of eyelid, lacrimal system and orbit
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 41962 | 22168 | 19588 |
| Only index persons | 39333 | 21012 | 18321 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.59 | 0.63 | 0.55 |
| Only index persons | 0.74 | 0.77 | 0.70 |
| Median age at first event (years) | |||
| Whole population | 42.34 | 41.84 | 42.98 |
| Only index persons | 42.78 | 42.32 | 43.31 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 4883 | 2861 | 2022 |
| Unadjusted period prevalence (%) | 0.94 | 0.98 | 0.89 |
| Median age at first event (years) | 49.12 | 46.92 | 52.22 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 4345
- Matched controls
- 43451
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
CBB00
NOMESCO Finland
Excision of chalazion
5108.6
323.0
1689
5
H00.1
ICD-10 Finland
Chalazion
4662.9
323.0
4203
214
H00.00
ICD-10 Finland
Hordeolum
12.9
322.2
598
529
H01.0
ICD-10 Finland
Blepharitis
10.0
276.9
586
665
H04.10
ICD-10 Finland
Dry eye syndrome
6.8
173.8
466
749
CBB30
NOMESCO Finland
Excision of lesion of eyelid
9.1
145.4
319
373
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.4
128.2
1523
8098
H02.3
ICD-10 Finland
Blepharochalasis
34.5
126.5
166
50
F72
ICPC
Blepharitis/stye/chalazion
10.6
117.2
235
232
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.2
115.2
1729
10129
D06BX01
ATC
metronidazole; topical
3.3
111.8
631
2119
37800
ICD-8 Finland
Other diseases of eye, Chalazion
+∞
110.9
106
*
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
4.9
68.8
236
501
H00
ICD-10 Finland
Hordeolum and chalazion
12.1
68.2
127
108
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
45.0
68.2
84
19
CBA00
NOMESCO Finland
Incision of eyelid
95.4
68.1
75
8
F29
ICPC
Eye symptom/complaint other
3.0
67.7
422
1492
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
64.6
60.5
70
11
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
67.5
52.2
60
9
J01AA07
ATC
tetracycline; systemic
2.0
48.2
707
3849
CBA10
NOMESCO Finland
Biopsy of eyelid
12.5
47.8
87
71
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.0
45.6
659
3560
H00.01
ICD-10 Finland
Abscess of the eyelid
53.6
44.6
53
10
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
26.9
44.2
61
23
H02.1
ICD-10 Finland
Ectropion of eyelid
421.6
42.2
42
*
H02.4
ICD-10 Finland
Ptosis of eyelid
13.0
38.7
69
54
J01DB01
ATC
cefalexin; oral
1.6
38.1
3380
29748
H10.5
ICD-10 Finland
Blepharoconjunctivitis
6.0
38.0
107
181
F16
ICPC
Eyelid symptom/complaint
3.1
38.0
222
744
CBB11
NOMESCO Finland
Resection of lax skin in upper eyelid
50.5
37.6
45
9
3732A
ICD-9 Finland
Inflammation of eyelids, Chalazion
+∞
37.5
36
*
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
24.7
34.9
49
20
S01GX01
ATC
cromoglicic acid; ophthalmic
1.7
32.6
776
4915
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
2.7
32.4
238
926
J01AA04
ATC
lymecycline; systemic
1.8
32.1
574
3320
L71.9
ICD-10 Finland
Rosacea, unspecified
4.3
32.0
123
295
J01DA01
ATC
[U] cefalexin; systemic
1.4
29.6
2456
20605
3202
FHL
Emptying and removing the eyelid in the operating room
293.9
28.8
29
*
H00.03
ICD-10 Finland
Preseptal cellulite in the eyelid
31.1
25.9
34
11
S01AA01
ATC
chloramphenicol; ophthalmic (antibiotics)
2.4
25.9
231
998
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
2.3
25.3
241
1074
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
25.0
1335
10172
N02AX02
ATC
tramadol; systemic, rectal
1.4
24.6
1516
11861
L71
ICD-10 Finland
Rosacea
3.8
24.3
105
281
L71.8
ICD-10 Finland
Other rosacea
5.1
24.3
78
156
H01.9
ICD-10 Finland
Inflammation of eyelid, unspecified
6.1
24.3
67
112
CBN30
NOMESCO Finland
Shortening of canthal ligament
+∞
24.0
23
*
ZXA05
NOMESCO Finland
Left side
1.5
23.9
877
6153
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
8.0
23.9
54
68
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
41.6
23.6
29
7
Z2221
NOMESCO Finland
Medical doctor
1.5
23.3
1035
7571
F03
ICPC
Eye discharge
2.2
22.5
235
1097
J01AA02
ATC
doxycycline; systemic
1.4
22.3
3008
26801
UJF32
NOMESCO Finland
Coloscopy
1.5
21.9
879
6276
S18
ICPC
Laceration/cut
1.4
21.6
1477
11707
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
2.2
21.6
231
1089
ZXA00
NOMESCO Finland
Right side
1.5
21.4
937
6815
H10
ICD-10 Finland
Conjunctivitis
2.1
21.0
239
1157
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
20.9
819
5810
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
20.8
789
5560
M79.6
ICD-10 Finland
Pain in limb
1.4
20.6
1272
9878
S01AX11
ATC
[U] ofloxacin; ophthalmic
2.7
19.9
136
509
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.8
19.9
354
2031
M25.5
ICD-10 Finland
Pain in joint
1.4
19.5
1021
7674
F73
ICPC
Eye infection/inflammation other
3.6
19.2
88
249
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.8
19.2
322
1810
WX110
NOMESCO Finland
Local anesthesy
1.3
18.9
2705
23949
L03
ICPC
Low back symptom/complaint
1.5
18.6
856
6267
L82
ICD-10 Finland
Seborrhoeic keratosis
1.6
18.3
511
3340
N02BE01
ATC
paracetamol; systemic, rectal
1.4
18.1
3400
31319
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
17.8
1361
10903
TCB40
NOMESCO Finland
Removal of chalzion
+∞
17.7
17
*
S29
ICPC
Skin symptom/complaint other
1.5
17.7
571
3869
M54.5
ICD-10 Finland
Low back pain
1.4
17.6
1167
9125
R51.80
ICD-10 Finland
Headache
1.6
17.6
528
3514
F01
ICPC
Eye pain
2.9
17.5
107
374
M03BX02
ATC
tizanidine; oral
1.3
17.2
2353
20545
R01AD09
ATC
mometasone; nasal
1.3
17.1
1665
13822
J05AB01
ATC
aciclovir; systemic
1.5
17.1
725
5210
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
17.0
780
5694
J02AC01
ATC
fluconazole; systemic
1.3
16.9
1434
11651
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.6
16.9
525
3518
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
16.9
2770
24794
H04.2
ICD-10 Finland
Epiphora
19.3
16.8
25
13
H10.4
ICD-10 Finland
Chronic conjunctivitis
6.7
16.7
42
63
M01AC06
ATC
meloxicam; systemic, rectal
1.4
16.6
1275
10195
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
16.6
951
7240
CBG00
NOMESCO Finland
Epilation of cilia by electrolysis
170.6
16.5
17
*
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
170.6
16.5
17
*
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
16.4
1825
15425
ZXA10
NOMESCO Finland
Bilateral
1.5
16.4
576
3973
A98
ICPC
Health maint/preventive medicine
1.7
16.1
4091
39330
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
16.1
787
5813
H02.8
ICD-10 Finland
Other specified disorders of eyelid
16.8
16.0
25
15
H16.0
ICD-10 Finland
Corneal ulcer
2.2
15.8
168
792
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
1.8
15.6
270
1535
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.6
15.4
478
3198
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
15.4
2518
22373
A02BC05
ATC
esomeprazole; systemic
1.3
15.1
1397
11452
L57.0
ICD-10 Finland
Actinic keratosis
1.8
15.1
264
1507
R74
ICPC
Upper respiratory infection acute
1.4
15.0
1048
8227
M01AB05
ATC
diclofenac; systemic, rectal
1.3
15.0
2502
22246
J01FA06
ATC
roxithromycin; oral
1.3
14.7
1431
11814
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
14.5
546
3816
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
14.5
587
4167
E0000UV
ATC
NA
1.3
14.5
1415
11681
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
14.5
866
6618
L17
ICPC
Foot/toe symptom/complaint
1.4
14.2
838
6383
A02BC02
ATC
pantoprazole; systemic
1.3
14.2
2336
20658
A02BC03
ATC
lansoprazole; oral
1.4
14.1
966
7550
M01AH05
ATC
etoricoxib; oral
1.3
14.0
2162
18947
N01
ICPC
Headache
1.6
13.9
373
2411
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
13.8
1566
13175
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
13.7
1609
13592
H02.9
ICD-10 Finland
Disorder of eyelid, unspecified
14.7
13.5
22
15
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
13.5
2008
17488
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
13.5
794
6045
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.6
13.4
324
2033
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
1.9
13.2
180
943
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.7
13.0
250
1472
Z01.2
ICD-10 Finland
Dental examination
1.3
13.0
1516
12777
H57.1
ICD-10 Finland
Ocular pain
2.4
12.9
104
431
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
19.1
12.9
19
10
XQ800
NOMESCO Finland
Prick test
1.7
12.9
258
1538
XCK10
NOMESCO Finland
Photography of fundus of eye
1.7
12.8
300
1868
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
12.8
2050
17970
R21
ICPC
Throat symptom/complaint
1.4
12.7
709
5338
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
12.7
2166
19119
D10BA01
ATC
isotretinoin; oral
1.7
12.7
244
1435
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
12.7
1018
8134
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.6
12.7
307
1931
CBN20
NOMESCO Finland
Shortening of eyelid retractors
70.1
12.6
14
*
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
12.6
1860
16129
CBN99
NOMESCO Finland
Other operation on eyelid for malposition
+∞
12.5
12
*
Z71.8
ICD-10 Finland
Other specified counselling
1.4
12.5
829
6428
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
12.4
584
4265
J02AC02
ATC
itraconazole; systemic
1.4
12.2
586
4296
KMAK
NOMESCO Finland
NA
1.3
12.2
1959
17140
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
12.1
303
1920
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.4
12.1
747
5722
J31.0
ICD-10 Finland
Chronic rhinitis
1.7
12.1
260
1582
R05
ICD-10 Finland
Cough
1.4
12.0
631
4702
E000001
ATC
NA
1.4
11.9
712
5424
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.4
11.9
510
3659
SPAT1153
SPAT
Removal of sutures
1.3
11.8
1044
8449
WX002
NOMESCO Finland
Sedation and analgesia
1.4
11.8
621
4629
N03AX16
ATC
pregabalin; oral
1.4
11.7
759
5858
J01FF01
ATC
clindamycin; systemic
1.3
11.6
911
7241
S82
ICPC
Naevus/mole
1.5
11.6
405
2782
H03.1*B00.5
ICD-10 Finland
Herpesviral dermatitis of eyelid
65.1
11.6
13
*
R06AE07
ATC
cetirizine; oral
1.3
11.5
1570
13430
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.1
11.5
124
593
R05
ICPC
Cough
1.4
11.5
743
5733
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
120.3
11.4
12
*
C44.11
ICD-10 Finland
Basocellular carcinoma of the skin of the eyelids including the corner of the eye
4.2
11.4
42
101
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
11.3
1296
10842
R01AD08
ATC
fluticasone; nasal
1.3
11.3
978
7879
CBB99
NOMESCO Finland
Other excision or destruction of lesion of eyelid
9.6
11.2
22
23
K02.1
ICD-10 Finland
Caries of dentine
1.2
11.2
2154
19166
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
2.2
11.1
113
526
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
11.0
3646
34613
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.6
11.0
317
2087
M02AA07
ATC
piroxicam; topical
1.3
10.9
1197
9950
M54
ICD-10 Finland
Dorsalgia
1.5
10.9
376
2576
U02
ICPC
Urinary frequency/urgency
1.5
10.8
410
2868
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
10.7
572
4266
L01
ICPC
Neck symptom/complaint
1.5
10.7
441
3138
R06AX27
ATC
desloratadine; oral
1.3
10.7
941
7593
CBB21
NOMESCO Finland
Correction of lax skin and resection of herniated fat in upper eyelid
60.1
10.6
12
*
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
10.6
809
6396
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.6
10.5
251
1577
H16.9
ICD-10 Finland
Keratitis, unspecified
2.9
10.3
60
207
R06.0
ICD-10 Finland
Dyspnoea
1.3
10.1
750
5898
L08
ICPC
Shoulder symptom/complaint
1.4
10.1
604
4592
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
10.1
1414
12090
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.5
10.1
352
2419
R01AD12
ATC
fluticasone furoate; nasal
1.3
10.0
1026
8441
S01XA18
ATC
ciclosporin; ophthalmic
9.1
10.0
20
22
D01BA02
ATC
terbinafine; oral; topical
1.3
9.9
807
6431
M48.0
ICD-10 Finland
Spinal stenosis
1.5
9.9
330
2242
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
9.9
1377
11753
R03DC03
ATC
montelukast; oral
1.4
9.9
522
3889
A02BC01
ATC
omeprazole; systemic
1.3
9.8
885
7155
H02AB06
ATC
prednisolone; systemic
1.2
9.7
1583
13750
S01GX05
ATC
lodoxamide; ophthalmic
3.2
9.7
48
149
A02BA02
ATC
ranitidine; systemic
1.4
9.7
593
4521
S01AD03
ATC
aciclovir; ophthalmic
2.1
9.7
108
524
N03AX12
ATC
gabapentin; oral
1.4
9.6
477
3509
F02
ICPC
Red eye
1.9
9.6
132
698
C44.10
ICD-10 Finland
Malignant tumor of the skin of the eyelids including the corner of the eye without histology
6.3
9.5
24
38
R42
ICD-10 Finland
Dizziness and giddiness
1.3
9.5
652
5067
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.2
9.5
1622
14158
A01AB04
ATC
amphotericin B; local oral
1.9
9.4
134
715
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.3
9.4
841
6784
J05AB11
ATC
valaciclovir; oral
1.4
9.3
407
2924
J30.0
ICD-10 Finland
Vasomotor rhinitis
2.3
9.3
83
365
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
3.2
9.3
46
143
XCH00
NOMESCO Finland
Eye pressure measurement
2.0
9.2
112
565
Z01.8
ICD-10 Finland
Other specified special examinations
1.3
9.2
697
5493
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
9.2
337
2339
M70.6
ICD-10 Finland
Trochanteric bursitis
1.5
9.1
333
2312
CFC00
NOMESCO Finland
Excision of lesion of conjunctiva
5.6
9.0
25
45
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.2
9.0
1287
10999
L72.1
ICD-10 Finland
Trichilemmal cyst
1.6
8.9
203
1258
TCC30
NOMESCO Finland
Intubation of lacrimal canaliculus/duct
18.6
8.9
13
7
A03FA02
ATC
cisapride; oral, rectal
1.6
8.9
224
1427
K03.64
ICD-10 Finland
Dental calculus supragingival
1.3
8.9
990
8211
S22
ICPC
Nail symptom/complaint
1.7
8.9
167
978
D10AX03
ATC
azelaic acid; topical
1.6
8.9
253
1657
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.5
8.9
343
2408
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.6
8.9
242
1574
M01AE02
ATC
naproxen; oral, rectal
1.2
8.8
2084
18756
S01KA02
ATC
hypromellose; ophthalmic
2.7
8.8
57
212
S01GX08
ATC
ketotifen; ophthalmic
1.9
8.8
117
612
J01FA10
ATC
azithromycin; systemic
1.2
8.7
2147
19392
F13
ICPC
Eye sensation abnormal
2.2
8.7
84
384
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.3
8.7
736
5891
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.7
8.7
187
1143
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.5
8.6
308
2130
R03AC03
ATC
terbutaline; inhalant
1.4
8.5
432
3192
UKC02
NOMESCO Finland
Cystoscopy
1.4
8.5
442
3279
M01AX17
ATC
nimesulide; oral
1.3
8.5
742
5965
CCD60
NOMESCO Finland
Transnasal dacryocystorhinostomy
90.2
8.4
9
*
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.6
8.4
238
1560
CCD50
NOMESCO Finland
Dacryocystorhinostomy with insertion of tube
+∞
8.3
8
*
CBD99
NOMESCO Finland
Other plastic reconstruction of eyelid
+∞
8.3
8
*
D01AE16
ATC
amorolfine; topical
1.4
8.3
340
2414
D19
ICPC
Teeth/gum symptom/complaint
1.3
8.3
898
7414
S01ED01
ATC
timolol; ophthalmic
2.1
8.2
93
457
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.4
8.2
336
2384
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.3
8.2
905
7486
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.7
8.2
174
1060
J01MA02
ATC
ciprofloxacin; systemic
1.2
8.2
1257
10805
G04CB01
ATC
finasteride; oral (testosterone-5-alpha reductase inhibitors)
1.5
8.2
255
1711
N17
ICPC
Vertigo/dizziness
1.5
8.1
314
2202
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
8.1
918
7617
SPAT1312
SPAT
General health counselling
1.2
8.1
1135
9656
CBJ50
NOMESCO Finland
Operation for ptosis of eyebrow
33.4
8.1
10
*
S21
ICPC
Skin texture symptom/complaint
1.4
8.0
373
2713
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
2.9
8.0
47
165
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
1.7
8.0
169
1027
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.5
8.0
243
1619
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.5
8.0
258
1745
F51.0
ICD-10 Finland
Nonorganic insomnia
1.4
8.0
407
3009
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
1.7
8.0
155
920
H02
ICPC
Hearing complaint
1.4
8.0
323
2288
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.2
8.0
1114
9473
N06AX11
ATC
mirtazapine; oral
1.2
7.9
1030
8685
M01AH01
ATC
celecoxib; oral (coxibs)
1.3
7.9
548
4257
D07XC01
ATC
betamethasone, combinations; topical
1.4
7.9
362
2629
H10.2
ICD-10 Finland
Other acute conjunctivitis
2.9
7.9
46
161
F70
ICPC
Conjunctivitis infectious
2.1
7.8
83
397
CBB50
NOMESCO Finland
Excision of lesion of eyelid and reconstruction using graft or flap
5.1
7.8
23
45
G04CA01
ATC
alfuzosin; oral
1.4
7.8
310
2187
H04.3
ICD-10 Finland
Acute and unspecified inflammation of lacrimal passages
10.8
7.8
14
13
CFA20
NOMESCO Finland
Biopsy of conjunctiva
9.4
7.8
15
16
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.5
7.8
294
2059
A04
ICPC
Weakness/tiredness general
1.4
7.8
380
2790
SFA40
NOMESCO Finland
Replacement of krone of tooth
1.3
7.7
664
5319
D07CC01
ATC
betamethasone and antibiotics; topical
1.4
7.7
401
2975
L04AX01
ATC
azathioprine; systemic
1.8
7.7
135
778
M79.1
ICD-10 Finland
Myalgia
1.4
7.7
395
2924
N40
ICD-10 Finland
Hyperplasia of prostate
1.3
7.7
522
4042
H93.1
ICD-10 Finland
Tinnitus
1.6
7.7
190
1207
H20.1
ICD-10 Finland
Chronic iridocyclitis
3.2
7.6
38
121
UJF30
NOMESCO Finland
Ileoscopy through colon
1.5
7.6
283
1976
D11
ICPC
Diarrhoea
1.4
7.5
357
2608
8090/3-C44.1
ICD-O-3
Basal cell carcinoma, NOS, of eyelid
4.5
7.5
25
56
H26.4
ICD-10 Finland
After-cataract
1.5
7.5
215
1415
H11.4
ICD-10 Finland
Other conjunctival vascular disorders and cysts
3.9
7.5
29
75
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.4
7.5
317
2265
S01ED51
ATC
timolol, combinations; ophthalmic
1.6
7.5
182
1151
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
4.6
7.5
24
52
G44.2
ICD-10 Finland
Tension-type headache
1.4
7.4
408
3058
S12
ICPC
Insect bite/sting
1.5
7.4
217
1438
H04.4
ICD-10 Finland
Chronic inflammation of lacrimal passages
80.2
7.4
8
*
C05AA08
ATC
fluocortolone; rectal, topical
1.4
7.4
433
3283
ZXE00
NOMESCO Finland
One hour or less
1.2
7.3
1328
11581
R03AC02
ATC
salbutamol; inhalant
1.2
7.3
1837
16517
R06AX22
ATC
ebastine; oral
1.3
7.3
543
4263
H05.2
ICD-10 Finland
Exophthalmic conditions
+∞
7.3
7
*
R03BA02
ATC
budesonide; inhalant
1.3
7.3
540
4235
G04CA02
ATC
tamsulosin; oral
1.3
7.3
577
4571
H02.2
ICD-10 Finland
Lagophthalmos
10.9
7.3
13
12
K30
ICD-10 Finland
Functional dyspepsia
1.4
7.2
312
2240
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
1.9
7.2
102
546
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.2
7.2
946
7975
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
1.5
7.2
202
1326
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
2.0
7.2
85
427
J45.9
ICD-10 Finland
Asthma, unspecified
1.3
7.2
523
4094
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.2
7.2
972
8225
Z00.0
ICD-10 Finland
General medical examination
1.3
7.2
577
4580
J01FA01
ATC
erythromycin; systemic
1.3
7.1
464
3569
CCA20
NOMESCO Finland
Incision of lacrimal punctum or canaliculus
30.0
7.1
9
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.4
7.1
401
3019
A07EC02
ATC
mesalazine; oral, rectal
1.6
7.1
173
1093
M01AX05
ATC
glucosamine; oral
1.3
7.1
551
4352
A99
ICPC
Disease/condition unspecnature/site
1.5
7.0
224
1513
M03BC51
ATC
orphenadrine, combinations; systemic
1.2
7.0
914
7698
XCK00
NOMESCO Finland
Perimetry
1.6
7.0
175
1117
D07AA02
ATC
hydrocortisone; topical
1.3
7.0
423
3220
M54.6
ICD-10 Finland
Pain in thoracic spine
1.5
7.0
204
1351
H25.1
ICD-10 Finland
Senile nuclear cataract
1.3
6.9
586
4684
R07.0
ICD-10 Finland
Pain in throat
1.6
6.9
186
1208
L02
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle
1.8
6.8
111
627
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.4
6.8
370
2767
D06BB10
ATC
imiquimod; topical
1.7
6.8
139
842
D07AB02
ATC
hydrocortisone butyrate; topical
1.2
6.8
904
7627
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
9.3
6.8
13
14
P01AB01
ATC
metronidazole; oral, rectal
1.2
6.7
1319
11576
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
1.5
6.7
192
1268
J01CA04
ATC
amoxicillin; systemic
1.2
6.7
3156
29910
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.6
6.7
167
1069
I83.9
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
1.4
6.6
290
2090
R4110
NOMESCO Finland
Physiotherapy
1.2
6.6
812
6789
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
1.3
6.6
403
3070
K11.2
ICD-10 Finland
Sialoadenitis
1.9
6.6
93
501
D01
ICPC
Abdominal pain/cramps general
1.4
6.6
331
2444
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
1.4
6.5
301
2187
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.3
6.5
516
4086
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.4
6.5
254
1790
37898
ICD-8 Finland
Other diseases of eye, Disease of eyeball, ocular muscle and orbit NEC
10.0
6.5
12
12
X58
ICD-10 Finland
Exposure to other specified factors
1.3
6.5
434
3357
CBF99
NOMESCO Finland
Other operation for ectropion
69.9
6.4
7
*
CBW99
NOMESCO Finland
Other operation on eyelid
69.9
6.4
7
*
8410/3-C44.1
ICD-O-3
Sebaceous carcinoma of eyelid
69.9
6.4
7
*
G04BD08
ATC
solifenacin; oral
1.6
6.4
172
1120
A02BX02
ATC
sucralfate; oral
1.8
6.4
109
627
J01EA01
ATC
trimethoprim; systemic
1.2
6.4
752
6254
L20.0
ICD-10 Finland
Besnier prurigo
1.5
6.4
206
1399
L12
ICPC
Hand/finger symptom/complaint
1.3
6.4
427
3304
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
1.5
6.3
233
1626
U71
ICPC
Cystitis/urinary infection other
1.6
6.3
172
1121
J01FA09
ATC
clarithromycin; systemic
1.2
6.3
1046
9021
H04.0
ICD-10 Finland
Dacryoadenitis
9.3
6.3
12
13
B00.10
ICD-10 Finland
Herpes simplex facialis
3.3
6.2
29
89
ZXD20
NOMESCO Finland
Day surgery
1.3
6.2
396
3035
A07AA02
ATC
nystatin; oral
1.6
6.2
164
1063
M54.2
ICD-10 Finland
Cervicalgia
1.5
6.2
206
1406
M67.4
ICD-10 Finland
Ganglion
1.5
6.2
186
1243
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.5
6.2
221
1532
R00.2
ICD-10 Finland
Palpitations
1.5
6.1
203
1384
L01
ICD-10 Finland
Impetigo
2.5
6.1
44
177
S01EE03
ATC
bimatoprost; ophthalmic
2.2
6.1
56
255
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.3
6.1
369
2809
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
2.0
6.1
72
363
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
1.4
6.1
338
2542
S01GX09
ATC
olopatadine; ophthalmic
2.0
6.0
74
379
CJB10
NOMESCO Finland
Laser discission of secondary cataract
1.5
6.0
183
1227
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
2.5
6.0
43
171
Mortality – FinRegistry
↥Association
Association between endpoint H7_CHALAZION and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CHALAZION | 0.864 [0.78, 0.96] | 0.005 |
| Birth year | 0.99 [0.98, 1.0] | 0.025 |
During the follow-up period (1.1.1998 — 31.12.2019), 1487 out of 19433 females with H7_CHALAZION died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CHALAZION | 0.841 [0.77, 0.92] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.018 |
During the follow-up period (1.1.1998 — 31.12.2019), 1880 out of 17221 males with H7_CHALAZION died.
Mortality risk
Mortality risk for people of age
years, who have H7_CHALAZION.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.045% | 0.174% |
| 5 | 0.42% | 1.046% |
| 10 | 1.075% | 2.673% |
| 15 | 2.027% | 5.117% |
| 20 | 3.582% | 8.531% |
Relationships between endpoints
↥Index endpoint: H7_CHALAZION – Chalazion
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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