Calcific tendinitis

M13_CALCTENDINITIS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M65.2
  • Cause of death: ICD-10 M65.2

2 out of 7 registries used, show all original rules.

342

4. Check minimum number of events

None

342

5. Include endpoints

None

342

6. Filter based on genotype QC (FinnGen only)

342

Control definitions (FinnGen only)

Control exclude
M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M65
Name in latin
Tendinitis calcificans

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2142 1286 852
Only index persons 2086 1262 824
Unadjusted period prevalence (%)
Whole population 0.03 0.04 0.02
Only index persons 0.04 0.05 0.03
Median age at first event (years)
Whole population 50.24 50.75 49.52
Only index persons 50.18 50.65 49.47

-FinnGen-

Key figures

All Female Male
Number of individuals 342 210 132
Unadjusted period prevalence (%) 0.07 0.07 0.06
Median age at first event (years) 52.66 50.49 56.11

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
307
Matched controls
3071
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M65.2
ICD-10 Finland
Calcific tendinitis
+∞
323.0
306
*
M75.1
ICD-10 Finland
Rotator cuff syndrome
10.3
60.2
137
222
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
42.8
50.2
62
18
M75.3
ICD-10 Finland
Calcific tendinitis of shoulder
283.2
48.5
48
*
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
33.4
40.7
53
19
NBG10
NOMESCO Finland
Acromioplastia
59.2
27.8
32
6
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
271.1
25.1
25
*
M01AH05
ATC
etoricoxib; oral
3.6
24.1
223
1293
M79.6
ICD-10 Finland
Pain in limb
3.9
23.9
126
466
N02AX02
ATC
tramadol; systemic, rectal
3.4
22.4
156
710
N03AX12
ATC
gabapentin; oral
5.4
21.1
69
157
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
14.0
20.4
35
28
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
25.7
19.0
26
11
N03AX16
ATC
pregabalin; oral
3.7
18.0
93
323
M01AB05
ATC
diclofenac; systemic, rectal
3.1
17.1
233
1558
M65.3
ICD-10 Finland
Trigger finger
16.3
17.0
27
18
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.8
16.7
162
870
M25.5
ICD-10 Finland
Pain in joint
3.0
14.9
106
459
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
22.4
14.9
21
10
M03BX02
ATC
tizanidine; oral
2.7
14.5
220
1481
M79.0
ICD-10 Finland
Rheumatism, unspecified
31.7
14.0
18
6
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
3.9
13.9
62
189
M54.4
ICD-10 Finland
Lumbago with sciatica
3.6
13.7
68
226
NHL16
NOMESCO Finland
Tenolysis or tenosynovectomy of achilles tendon
146.2
13.6
14
*
M48.0
ICD-10 Finland
Spinal stenosis
4.8
13.5
46
108
M19.0
ICD-10 Finland
Primary arthrosis of other joints
4.9
13.0
44
102
M01AH01
ATC
celecoxib; oral (coxibs)
3.2
12.5
74
279
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
135.3
12.5
13
*
M02AA07
ATC
piroxicam; topical
2.5
12.2
128
682
NBF25
NOMESCO Finland
Operation for humeroscapular osteochondritis, arthroscopic
22.4
12.1
17
8
M54.5
ICD-10 Finland
Low back pain
2.6
11.4
105
515
M01AC06
ATC
meloxicam; systemic, rectal
2.4
11.4
130
718
H02AB06
ATC
prednisolone; systemic
2.3
11.4
156
942
N02BE01
ATC
paracetamol; systemic, rectal
3.0
10.9
270
2177
M03BC01
ATC
orphenadrine (citrate); systemic
2.7
10.8
87
397
G56.0
ICD-10 Finland
Carpal tunnel syndrome
3.4
10.7
55
186
M01AX17
ATC
nimesulide; oral
2.7
10.7
87
398
M67.4
ICD-10 Finland
Ganglion
8.2
10.6
23
30
A02BC03
ATC
lansoprazole; oral
2.4
10.5
106
545
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
7.3
10.3
24
35
M75.2
ICD-10 Finland
Bicipital tendinitis
14.0
9.8
16
12
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
4.9
9.6
31
69
Z01.8
ICD-10 Finland
Other specified special examinations
2.6
9.5
78
357
M01AB55
ATC
diclofenac, combinations; oral
4.6
9.4
32
75
M01AE02
ATC
naproxen; oral, rectal
2.1
9.4
181
1235
N02AJ06
ATC
codeine and paracetamol; systemic
2.2
9.3
116
655
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.0
9.2
37
102
UJF32
NOMESCO Finland
Coloscopy
2.4
9.1
86
421
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.2
9.0
128
765
N06AA09
ATC
amitriptyline; systemic
3.7
8.8
38
112
9242
FHL
Other reconstruction or plastic surgery of shoulder joint (including ac joint)
51.5
8.7
10
*
M01AE03
ATC
ketoprofen; systemic, rectal
2.1
8.7
126
753
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.9
8.7
54
209
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.3
8.5
94
496
M79.1
ICD-10 Finland
Myalgia
3.6
8.4
38
117
ACC51
NOMESCO Finland
Release of median nerve
4.1
8.3
32
85
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
6.8
8.3
20
31
NDM10
NOMESCO Finland
Palmar fasciotomy of hand
34.3
8.1
10
*
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.2
8.1
92
492
M70.6
ICD-10 Finland
Trochanteric bursitis
3.2
8.1
42
144
L08
ICPC
Shoulder symptom/complaint
2.6
8.0
64
284
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
8.0
91
485
A02BC01
ATC
omeprazole; systemic
2.2
7.9
91
488
J01DB01
ATC
cefalexin; oral
2.3
7.8
250
2026
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.5
7.8
36
113
SFA10
NOMESCO Finland
Fillning on one surface of tooth
2.0
7.8
165
1137
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
4.6
7.7
26
61
SPAT1263
SPAT
Sampling
2.0
7.6
126
785
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
4.3
7.6
27
67
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
7.4
7.6
17
24
NDA30
NOMESCO Finland
Exploration of joint of wrist or hand, arthroscopic
82.0
7.4
8
*
R42
ICD-10 Finland
Dizziness and giddiness
2.4
7.4
65
304
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.9
7.3
180
1297
7261A
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Rotator cuff syndrome of shoulder and allied disorders[TENDINITIS CALCIFICANS HUMEROSCAPULARIS]
+∞
7.3
7
*
L03
ICPC
Low back symptom/complaint
2.3
7.3
72
359
SPAT1153
SPAT
Removal of sutures
2.1
7.3
103
600
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.4
7.2
62
288
R01AD09
ATC
mometasone; nasal
1.9
7.2
144
962
M75.5
ICD-10 Finland
Bursitis of shoulder
12.4
7.1
12
10
M53.1
ICD-10 Finland
Cervicobrachial syndrome
3.0
7.0
40
145
SPAT1260
SPAT
Consultation of another employee
2.4
7.0
59
272
N06AX21
ATC
duloxetine; oral
3.2
7.0
36
123
J01CA04
ATC
amoxicillin; systemic
2.1
6.9
244
1992
S18
ICPC
Laceration/cut
2.0
6.9
125
799
M77.1
ICD-10 Finland
Lateral epicondylitis
4.1
6.8
25
65
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.1
6.8
36
126
K02.1
ICD-10 Finland
Caries of dentine
1.9
6.7
167
1195
NBT60
NOMESCO Finland
Forcible manipulation of humeroscapular joint
23.1
6.7
9
*
SAA02
NOMESCO Finland
Basic examination of mouth
1.9
6.7
191
1430
J01DA01
ATC
[U] cefalexin; systemic
1.9
6.7
194
1462
J01AA02
ATC
doxycycline; systemic
2.1
6.6
244
2002
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
12.6
6.6
11
9
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
6.6
100
595
R07.4
ICD-10 Finland
Chest pain, unspecified
2.1
6.6
82
450
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.2
6.6
69
353
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.9
6.5
149
1031
M76.6
ICD-10 Finland
Achilles tendinitis
6.2
6.4
16
27
J45.9
ICD-10 Finland
Asthma, unspecified
2.4
6.4
57
269
A02BC02
ATC
pantoprazole; systemic
1.9
6.4
195
1484
A02BC05
ATC
esomeprazole; systemic
1.9
6.3
124
811
R03AC02
ATC
salbutamol; inhalant
1.8
6.3
157
1113
M72.0
ICD-10 Finland
Palmar fascial fibromatosis [Dupuytren]
18.5
6.3
9
5
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.8
6.3
168
1218
R03DC03
ATC
montelukast; oral
2.4
6.3
54
250
NB1ZT
NOMESCO Finland
Crushing of soft tissue calcifications in shoulder wiht ultrasound quidance
+∞
6.3
6
*
NBL50
NOMESCO Finland
Tenolysis or tenosynovectomy of shoulder or upper arm
+∞
6.3
6
*
H02BX01
ATC
methylprednisolone, combinations; systemic
4.4
6.3
21
50
WX204
NOMESCO Finland
Axillary plexus blockaced
6.5
6.2
15
24
WX400
NOMESCO Finland
Inhalation anesthesy
4.9
6.2
19
41
P01AB01
ATC
metronidazole; oral, rectal
1.9
6.2
128
851
M02AA10
ATC
ketoprofen; topical
2.4
6.1
54
254
M65.4
ICD-10 Finland
Radial styloid tenosynovitis [de Quervain]
12.9
6.1
10
8
M54.6
ICD-10 Finland
Pain in thoracic spine
3.5
6.1
27
83

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
82
402
2.37
9.67
1.3
1.2
5.1
20.1
u/ml
1.67
42
159
118
675
2.14
9.57
2.8
2.6
335.7
10822.0
umol/l
4.41
103
578
85
434
2.28
9.08
1.3
1.2
25.1
39.6
iu/ml
0.77
25
154
255
1998
2.09
8.05
4.9
3.6
11.9
11.8
mm/h
0.06
245
1846
269
2156
2.16
7.90
4.2
3.8
14.8
14.7
pmol/l
0.31
247
1962
266
2169
2.02
6.79
6.4
7.8
72.1
79.9
u/l
3.60
254
2044
315
2785
2.66
5.95
14.2
12.8
21.2
24.1
mg/l
0.77
255
2155
174
1280
1.73
5.83
3.9
3.2
0.0
0.0
estimate
0.00
39
224
175
1314
1.68
5.25
3.9
3.2
0.0
0.0
estimate
0.00
39
214
173
1296
1.68
5.23
4.8
4.5
0.0
0.0
estimate
0.00
39
225
298
2607
2.11
5.20
5.2
4.4
2.0
1.9
mu/l
0.51
276
2379
102
663
1.77
5.17
4.7
3.4
0.0
0.0
estimate
0.50
38
217
306
2717
2.20
4.92
6.7
5.3
40.9
39.6
mmol/mol
1.46
286
2533
41
199
2.20
4.84
1.6
1.5
—
—
—
0
0
322
2928
2.71
4.78
4.9
4.4
4.7
4.8
mmol/l
1.06
298
2742
327
3003
3.03
4.63
14.7
11.9
—
—
—
0
0
224
1833
1.64
4.49
4.4
3.8
—
—
—
0
0
53
292
1.96
4.48
1.9
2.5
250.0
138.8
ug/g
0.38
39
244
320
2916
2.51
4.46
4.8
4.3
1.4
1.5
mmol/l
2.32
298
2708
174
1345
1.60
4.37
6.5
7.1
1.2
1.2
mmol/l
0.17
140
1146
84
545
1.72
4.20
4.3
3.5
1.0
1.0
kg/l
0.08
12
82
324
2983
2.64
4.16
5.3
4.8
2.8
2.8
mmol/l
1.07
299
2770
192
1535
1.57
4.06
4.6
4.9
6.8
6.7
mmol/l
0.15
181
1443
117
838
1.60
3.96
2.6
2.4
53.2
59.9
u/l
1.80
107
777
311
2828
2.10
3.90
4.4
3.9
1.4
1.3
mmol/l
1.98
289
2622
109
775
1.60
3.78
2.4
2.1
190.9
193.3
u/l
0.02
98
728
312
2856
2.05
3.59
4.8
4.4
6.2
5.9
mmol/l
1.89
283
2633
36
188
2.02
3.54
3.5
3.5
—
—
—
0
0
172
1369
1.52
3.53
5.8
5.4
2.0
2.0
e9/l
0.28
155
1205
322
2991
2.31
3.42
15.3
14.7
4.0
4.0
mmol/l
0.43
317
2917
32
163
2.06
3.37
4.2
7.8
—
—
—
0
0
329
3088
2.72
3.35
10.8
10.0
28.0
26.3
u/l
0.72
320
2979
153
1200
1.50
3.31
5.1
6.2
1.2
1.2
mmol/l
0.05
132
1094
26
124
2.19
3.23
1.3
1.3
—
—
—
0
0
81
557
1.60
3.17
3.6
3.3
—
—
—
0
0
48
291
1.76
3.02
2.3
1.6
—
—
—
0
0
52
323
1.72
3.01
1.3
1.3
1268.6
418.8
titre
—
7
66
166
1345
1.46
2.95
5.7
5.4
0.6
0.6
e9/l
1.12
149
1154
335
3214
3.07
2.90
21.3
18.7
4.5
4.5
e12/l
0.24
328
3129
335
3214
3.07
2.90
21.3
18.8
6.9
6.5
e9/l
3.31
328
3129
335
3213
3.08
2.90
21.1
18.7
258.8
252.8
e9/l
1.09
330
3135
57
368
1.66
2.86
1.2
1.2
—
—
—
0
0
170
1389
1.45
2.86
5.9
5.8
0.2
0.2
e9/l
1.99
153
1218
166
1352
1.44
2.83
5.7
5.4
0.0
0.0
e9/l
0.50
149
1162
127
990
1.45
2.71
4.6
3.3
99.3
29.2
ng/l
0.50
89
668
36
207
1.83
2.70
3.5
4.0
0.3
0.6
%
—
6
54
79
560
1.53
2.69
1.2
1.2
1.5
2.0
u/ml
0.16
29
147
148
1193
1.42
2.61
4.2
4.8
36.0
35.8
g/l
0.25
138
1129
35
203
1.81
2.56
4.3
4.3
0.0
0.1
%
—
7
54
36
212
1.78
2.51
4.1
4.3
0.0
0.1
%
—
8
64
78
564
1.50
2.41
1.9
1.7
1.0
1.2
mg/l
0.34
62
436
38
232
1.72
2.35
4.0
4.1
0.5
1.0
%
—
8
75
135
1088
1.40
2.32
5.9
8.0
1.2
1.2
inr
0.36
36
325
16
72
2.28
2.31
1.1
1.1
—
—
—
0
0
173
1455
1.38
2.30
4.8
7.2
10.3
11.4
umol/l
0.91
163
1394
12
47
2.61
2.29
1.2
1.2
495.1
431.1
mg/l
0.29
12
42
155
1286
1.38
2.21
5.7
5.3
56.7
56.9
%
0.06
141
1199
112
882
1.40
2.18
4.9
5.5
—
—
—
0
0
45
294
1.61
2.17
3.8
9.6
2.1
1.0
mmol/l
1.22
34
235
156
1301
1.37
2.14
5.9
5.6
29.4
28.1
%
0.80
144
1206
80
599
1.44
2.06
4.9
4.6
—
—
—
0
0
74
549
1.44
2.00
1.8
1.7
109836499.6
23739925.8
pmol/l
0.35
61
476
7
21
3.38
1.97
1.0
1.0
—
—
—
0
0
145
1214
1.34
1.87
4.3
3.9
—
—
—
0
0
151
1273
1.33
1.86
6.4
5.7
8.4
8.8
%
0.69
141
1190
44
298
1.55
1.84
1.6
1.5
—
—
—
0
0
95
748
1.37
1.82
3.8
2.9
—
—
—
0
0
150
1267
1.33
1.81
5.8
5.4
3.0
2.8
%
0.49
139
1176
101
808
1.35
1.75
3.4
3.1
55.9
293.9
mg/l
1.00
76
515
8
30
2.71
1.73
3.1
3.3
3.2
4.2
e9/l
—
8
30
230
2076
1.33
1.68
4.2
3.6
—
—
—
0
0
49
347
1.48
1.68
3.1
2.4
23.1
23.1
%
0.00
41
302
181
1587
1.30
1.61
7.5
9.7
4.3
4.0
e9/l
1.17
165
1388
8
32
2.54
1.60
1.1
1.3
—
—
—
0
0
8
32
2.54
1.60
4.1
3.4
53.5
55.5
%
—
8
32
16
283
0.54
1.60
2.1
1.4
—
—
—
0
0
145
1236
1.30
1.59
10.8
8.8
0.0
0.0
e9/l
0.03
127
1011
106
866
1.32
1.58
3.9
3.7
15.7
7.5
mg/mmol
0.72
81
539
144
1230
1.29
1.54
5.6
5.4
0.8
0.7
%
1.20
134
1146
22
132
1.71
1.50
2.5
2.4
—
—
—
0
0
60
453
1.39
1.47
2.0
1.7
1214.9
1181.9
nmol/l
0.11
48
344
103
847
1.31
1.45
3.3
2.9
7.8
7.7
mmol/l
0.04
94
716
7
29
2.44
1.40
1.6
1.3
—
—
—
0
0
16
89
1.84
1.39
6.1
3.8
—
—
—
0
0
98
806
1.30
1.38
4.6
3.6
—
—
—
0
0
0
37
0.00
1.35
0.0
1.1
—
—
—
0
0
0
37
0.00
1.35
0.0
1.6
—
—
—
0
0
9
43
2.12
1.31
1.8
3.8
—
—
—
0
0
66
517
1.34
1.30
2.9
2.3
8.0
7.4
e6/l
0.09
61
445
5
18
2.80
1.29
1.0
1.3
—
—
—
0
0
108
909
1.27
1.26
2.9
3.9
2.3
2.4
mmol/l
0.49
95
819
8
37
2.19
1.22
1.0
1.3
—
—
—
0
0
84
688
1.29
1.21
2.6
2.7
—
—
—
0
0
36
258
1.44
1.20
1.3
1.5
—
—
—
0
0
14
79
1.81
1.18
1.3
1.4
375.6
324.3
ug/g
—
8
44
11
57
1.96
1.18
1.6
1.8
—
—
—
0
0
13
72
1.84
1.16
1.3
1.1
—
—
—
0
0
8
40
2.02
1.13
1.3
1.5
—
—
—
0
0
13
73
1.81
1.12
1.5
1.3
0.2
0.2
g/l
1.34
13
67
7
31
2.28
1.11
1.9
1.9
1.4
1.7
mmol/l
—
7
31
35
256
1.41
1.06
4.6
4.6
—
—
—
0
0
13
75
1.76
1.04
1.5
1.3
1.1
1.2
g/l
0.79
13
70
29
397
0.71
1.01
1.4
1.2
—
—
—
0
0
5
23
2.19
0.98
3.8
2.5
—
—
—
0
0
74
613
1.26
0.98
2.6
2.0
3.0
3.1
mg/l
0.26
69
520
7
36
1.96
0.97
1.3
1.1
—
—
—
0
0
0
31
0.00
0.97
0.0
1.7
—
—
—
0
0
24
167
1.47
0.95
1.3
1.3
—
—
—
0
0
26
184
1.45
0.95
3.2
3.4
4.3
4.0
e9/l
0.42
17
146
28
202
1.42
0.93
2.7
2.8
68.0
68.9
e9/l
0.05
21
153
15
94
1.62
0.92
2.7
4.2
0.2
0.2
g/l
—
6
41
131
1163
1.20
0.90
2.8
2.5
138.8
143.3
ug/l
0.07
123
1077
17
112
1.54
0.86
3.1
3.9
—
—
—
0
0
43
338
1.31
0.86
2.2
1.7
—
—
—
0
0
8
45
1.80
0.85
1.4
1.2
—
—
—
0
0
6
31
1.95
0.85
3.0
3.6
4.2
3.7
nmol/l
—
6
31
6
111
0.53
0.84
1.3
1.6
—
—
—
0
0
21
146
1.47
0.84
3.8
14.4
—
—
—
0
0
8
46
1.76
0.83
2.1
2.8
—
—
—
0
0
99
863
1.21
0.82
4.3
4.8
16.3
2.7
ug/l
0.47
78
774
11
66
1.69
0.79
2.4
1.4
37.3
43.6
nmol/l
0.46
11
66
60
499
1.25
0.78
3.5
3.7
314.6
409.6
ng/l
0.15
47
390
94
820
1.20
0.77
3.3
4.0
7.4
7.4
ph
0.39
25
149
44
355
1.27
0.74
2.5
2.2
—
—
—
0
0
118
1055
1.18
0.74
2.0
1.9
105.1
95.7
pmol/l
1.20
64
551
5
25
2.01
0.73
2.4
2.5
—
—
—
0
0
15
101
1.51
0.71
1.1
1.2
—
—
—
0
0
5
26
1.94
0.71
1.0
1.0
—
—
—
0
0
24
317
0.74
0.70
2.0
2.5
19.7
8.5
umol/l
0.38
17
276
38
304
1.28
0.69
1.2
1.3
—
—
—
0
0
25
189
1.35
0.66
1.2
1.1
—
—
—
0
0
252
2406
1.18
0.66
15.9
15.6
13.6
13.7
%
1.08
247
2352
5
29
1.73
0.64
1.0
1.2
—
—
—
0
0
27
209
1.32
0.62
1.4
1.3
—
—
—
0
0
63
727
0.84
0.61
1.3
1.3
—
—
—
0
0
127
1158
1.15
0.61
1.8
2.1
—
—
—
0
0
0
21
0.00
0.60
0.0
12.6
—
798.3
—
0
21
0
21
0.00
0.60
0.0
15.7
—
1468.1
—
0
21
15
108
1.41
0.54
1.7
1.6
1.4
1.6
g/l
0.29
15
97
21
161
1.32
0.53
2.8
3.2
—
—
—
0
0
32
261
1.25
0.52
2.0
1.6
—
—
—
0
0
14
101
1.40
0.50
1.8
1.6
—
—
—
0
0
5
81
0.61
0.46
1.4
1.2
—
—
—
0
0
83
749
1.14
0.46
2.7
2.7
—
—
—
0
0
34
284
1.22
0.46
2.0
1.5
—
—
—
0
0
17
131
1.31
0.43
1.1
1.1
—
132.0
—
0
5
8
57
1.41
0.42
2.1
2.9
8.3
7.9
kpa
—
8
52
19
150
1.28
0.41
4.1
9.9
94.6
93.3
%
0.92
19
150
56
496
1.15
0.40
2.9
2.5
564.3
570.9
mosm/kgh2o
0.07
49
421
0
18
0.00
0.40
0.0
1.7
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
57
509
1.14
0.37
1.5
1.4
2.7
2.4
g/l
0.40
41
331
10
72
1.40
0.37
1.7
3.1
—
—
—
0
0
6
41
1.47
0.36
1.2
1.1
—
—
—
0
0
6
46
1.31
0.33
1.5
1.5
—
—
—
0
0
6
46
1.31
0.33
1.2
1.1
—
—
—
0
0
6
47
1.28
0.32
1.2
1.1
—
—
—
0
0
78
720
1.11
0.31
2.8
2.7
0.7
0.8
e6/l
0.12
62
533
98
916
1.10
0.30
3.7
3.3
78.0
67.8
e6/l
0.13
71
651
85
789
1.10
0.30
3.3
2.9
76.5
167.9
e6/l
0.43
66
607
8
65
1.24
0.27
1.1
1.1
—
—
—
0
0
8
66
1.22
0.27
2.6
5.2
—
—
—
0
0
12
95
1.27
0.26
12.2
7.7
—
—
—
0
0
8
67
1.20
0.26
3.3
1.5
—
—
—
0
0
8
67
1.20
0.26
3.9
1.5
—
—
—
0
0
8
67
1.20
0.26
3.3
1.5
—
—
—
0
0
37
333
1.12
0.23
1.6
1.4
—
—
—
0
0
5
38
1.32
0.23
1.0
1.4
—
—
—
0
0
5
40
1.25
0.22
1.6
1.9
31.4
33.5
pg
—
5
40
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
11
134
0.81
0.21
1.8
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
21
183
1.16
0.20
1.0
1.3
24.3
148.5
iu/ml
—
7
83
18
208
0.86
0.20
3.2
3.2
9.6
10.7
g/l
0.53
18
195
15
127
1.19
0.20
1.1
1.1
—
—
—
0
0
18
157
1.15
0.17
2.7
3.4
4.2
4.4
pmol/l
0.41
18
144
7
62
1.13
0.17
3.6
1.5
—
—
—
0
0
8
68
1.18
0.16
3.4
1.5
—
—
—
0
0
15
131
1.15
0.14
2.5
3.5
—
—
—
0
0
64
673
0.94
0.14
6.1
7.5
—
—
—
0
0
30
325
0.92
0.14
1.4
1.4
—
—
—
0
0
19
173
1.10
0.10
1.7
1.5
—
—
—
0
0
16
177
0.90
0.10
1.9
1.8
—
—
—
0
0
5
44
1.14
0.10
2.6
2.9
3.7
4.0
mmol/l
—
5
44
5
44
1.14
0.10
2.6
2.9
101.8
105.0
mmol/l
—
5
44
5
44
1.14
0.10
5.4
3.8
—
—
—
0
0
5
46
1.09
0.09
2.6
2.0
—
—
—
0
0
10
114
0.87
0.09
3.0
2.4
—
—
—
0
0
6
57
1.05
0.08
3.0
3.7
7.5
7.4
ph
—
6
43
5
64
0.78
0.08
1.2
1.2
—
—
—
0
0
79
813
0.96
0.08
1.7
1.7
1.3
1.4
mmol/l
0.44
71
683
6
70
0.85
0.07
1.0
1.1
—
—
—
0
0
6
73
0.82
0.07
3.0
2.6
1.3
1.5
mg/l
—
6
67
8
78
1.03
0.07
2.0
4.1
—
—
—
0
0
261
2630
0.97
0.07
13.5
13.8
39.3
40.3
%
0.68
170
1909
27
259
1.05
0.04
4.1
3.0
—
—
—
0
0
14
131
1.07
0.03
1.9
1.3
25.6
32.6
iu/l
0.37
14
110
14
131
1.07
0.03
4.1
2.3
1.2
1.2
%
0.04
14
131
114
1154
0.98
0.03
3.1
2.8
—
—
—
0
0
60
591
1.02
0.02
1.6
1.4
19.1
21.0
nmol/l
0.45
50
495
32
328
0.97
0.02
2.1
5.2
7.2
49.1
ug/l
0.98
25
270
17
164
1.04
0.00
2.5
2.6
—
—
—
0
0
22
214
1.03
0.00
5.1
3.0
—
—
—
0
0
22
218
1.01
0.00
3.6
7.6
1.3
1.4
mmol/l
0.17
22
210
22
218
1.01
0.00
3.3
8.2
—
—
—
0
0
18
179
1.01
0.00
1.7
1.5
—
—
—
0
0
22
219
1.00
0.00
15.6
9.0
11.6
9.8
mmol/l
0.45
22
206
31
313
0.99
0.00
13.4
17.7
1.4
1.2
inr
—
5
44
84
837
1.00
0.00
2.2
2.3
—
—
—
0
0
70
703
0.99
0.00
4.8
4.0
—
—
—
0
0
50
505
0.99
0.00
2.4
2.9
0.7
0.7
ug/l
0.13
27
340
6
66
0.91
0.00
1.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
16.2
—
0
5
0
5
0.00
0.00
0.0
1.0
—
6.2
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
6
64
0.94
0.00
2.8
2.3
27.5
30.8
umol/l
—
6
55
0
8
0.00
0.00
0.0
2.8
—
6.9
—
0
8
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
3.3
—
0
8
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_CALCTENDINITIS and mortality.

Females

Parameter HR [95% CI] p-value
M13_CALCTENDINITIS 0.851 [0.67, 1.07] 0.175
Birth year 0.995 [0.99, 1.0] 0.238

During the follow-up period (1.1.1998 — 31.12.2019), 71 out of 1127 females with M13_CALCTENDINITIS died.

Males

Parameter HR [95% CI] p-value
M13_CALCTENDINITIS 0.862 [0.68, 1.09] 0.209
Birth year 0.988 [0.98, 1.0] 0.029

During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 721 males with M13_CALCTENDINITIS died.

Mortality risk

Mortality risk for people of age

years, who have M13_CALCTENDINITIS.

N-year risk Females Males
1 0.077% 0.162%
5 0.494% 0.958%
10 1.316% 2.609%
15 2.429% 4.989%
20 4.252% 8.412%

Relationships between endpoints

Index endpoint: M13_CALCTENDINITIS – Calcific tendinitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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