No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
342 |
4. Check minimum number of eventsNone |
342 |
5. Include endpointsNone |
342 |
6. Filter based on genotype QC (FinnGen only) |
342 |
Control definitions (FinnGen only)
- Control exclude
- M13_SOFTTISSUE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M65
- Name in latin
- Tendinitis calcificans
Similar endpoints
↥List of similar endpoints to
Calcific tendinitis
based on the number of shared cases.
Similar with more cases:
- Disorders of synovium and tendon
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2142 | 1286 | 852 |
| Only index persons | 2086 | 1262 | 824 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.04 | 0.02 |
| Only index persons | 0.04 | 0.05 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 50.24 | 50.75 | 49.52 |
| Only index persons | 50.18 | 50.65 | 49.47 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 342 | 210 | 132 |
| Unadjusted period prevalence (%) | 0.07 | 0.07 | 0.06 |
| Median age at first event (years) | 52.66 | 50.49 | 56.11 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 307
- Matched controls
- 3071
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M65.2
ICD-10 Finland
Calcific tendinitis
+∞
323.0
306
*
M75.1
ICD-10 Finland
Rotator cuff syndrome
10.3
60.2
137
222
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
42.8
50.2
62
18
M75.3
ICD-10 Finland
Calcific tendinitis of shoulder
283.2
48.5
48
*
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
33.4
40.7
53
19
NBG10
NOMESCO Finland
Acromioplastia
59.2
27.8
32
6
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
271.1
25.1
25
*
M01AH05
ATC
etoricoxib; oral
3.6
24.1
223
1293
M79.6
ICD-10 Finland
Pain in limb
3.9
23.9
126
466
N02AX02
ATC
tramadol; systemic, rectal
3.4
22.4
156
710
N03AX12
ATC
gabapentin; oral
5.4
21.1
69
157
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
14.0
20.4
35
28
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
25.7
19.0
26
11
N03AX16
ATC
pregabalin; oral
3.7
18.0
93
323
M01AB05
ATC
diclofenac; systemic, rectal
3.1
17.1
233
1558
M65.3
ICD-10 Finland
Trigger finger
16.3
17.0
27
18
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.8
16.7
162
870
M25.5
ICD-10 Finland
Pain in joint
3.0
14.9
106
459
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
22.4
14.9
21
10
M03BX02
ATC
tizanidine; oral
2.7
14.5
220
1481
M79.0
ICD-10 Finland
Rheumatism, unspecified
31.7
14.0
18
6
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
3.9
13.9
62
189
M54.4
ICD-10 Finland
Lumbago with sciatica
3.6
13.7
68
226
NHL16
NOMESCO Finland
Tenolysis or tenosynovectomy of achilles tendon
146.2
13.6
14
*
M48.0
ICD-10 Finland
Spinal stenosis
4.8
13.5
46
108
M19.0
ICD-10 Finland
Primary arthrosis of other joints
4.9
13.0
44
102
M01AH01
ATC
celecoxib; oral (coxibs)
3.2
12.5
74
279
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
135.3
12.5
13
*
M02AA07
ATC
piroxicam; topical
2.5
12.2
128
682
NBF25
NOMESCO Finland
Operation for humeroscapular osteochondritis, arthroscopic
22.4
12.1
17
8
M54.5
ICD-10 Finland
Low back pain
2.6
11.4
105
515
M01AC06
ATC
meloxicam; systemic, rectal
2.4
11.4
130
718
H02AB06
ATC
prednisolone; systemic
2.3
11.4
156
942
N02BE01
ATC
paracetamol; systemic, rectal
3.0
10.9
270
2177
M03BC01
ATC
orphenadrine (citrate); systemic
2.7
10.8
87
397
G56.0
ICD-10 Finland
Carpal tunnel syndrome
3.4
10.7
55
186
M01AX17
ATC
nimesulide; oral
2.7
10.7
87
398
M67.4
ICD-10 Finland
Ganglion
8.2
10.6
23
30
A02BC03
ATC
lansoprazole; oral
2.4
10.5
106
545
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
7.3
10.3
24
35
M75.2
ICD-10 Finland
Bicipital tendinitis
14.0
9.8
16
12
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
4.9
9.6
31
69
Z01.8
ICD-10 Finland
Other specified special examinations
2.6
9.5
78
357
M01AB55
ATC
diclofenac, combinations; oral
4.6
9.4
32
75
M01AE02
ATC
naproxen; oral, rectal
2.1
9.4
181
1235
N02AJ06
ATC
codeine and paracetamol; systemic
2.2
9.3
116
655
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.0
9.2
37
102
UJF32
NOMESCO Finland
Coloscopy
2.4
9.1
86
421
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.2
9.0
128
765
N06AA09
ATC
amitriptyline; systemic
3.7
8.8
38
112
9242
FHL
Other reconstruction or plastic surgery of shoulder joint (including ac joint)
51.5
8.7
10
*
M01AE03
ATC
ketoprofen; systemic, rectal
2.1
8.7
126
753
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.9
8.7
54
209
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.3
8.5
94
496
M79.1
ICD-10 Finland
Myalgia
3.6
8.4
38
117
ACC51
NOMESCO Finland
Release of median nerve
4.1
8.3
32
85
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
6.8
8.3
20
31
NDM10
NOMESCO Finland
Palmar fasciotomy of hand
34.3
8.1
10
*
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.2
8.1
92
492
M70.6
ICD-10 Finland
Trochanteric bursitis
3.2
8.1
42
144
L08
ICPC
Shoulder symptom/complaint
2.6
8.0
64
284
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
8.0
91
485
A02BC01
ATC
omeprazole; systemic
2.2
7.9
91
488
J01DB01
ATC
cefalexin; oral
2.3
7.8
250
2026
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.5
7.8
36
113
SFA10
NOMESCO Finland
Fillning on one surface of tooth
2.0
7.8
165
1137
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
4.6
7.7
26
61
SPAT1263
SPAT
Sampling
2.0
7.6
126
785
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
4.3
7.6
27
67
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
7.4
7.6
17
24
NDA30
NOMESCO Finland
Exploration of joint of wrist or hand, arthroscopic
82.0
7.4
8
*
R42
ICD-10 Finland
Dizziness and giddiness
2.4
7.4
65
304
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.9
7.3
180
1297
7261A
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Rotator cuff syndrome of shoulder and allied disorders[TENDINITIS CALCIFICANS HUMEROSCAPULARIS]
+∞
7.3
7
*
L03
ICPC
Low back symptom/complaint
2.3
7.3
72
359
SPAT1153
SPAT
Removal of sutures
2.1
7.3
103
600
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.4
7.2
62
288
R01AD09
ATC
mometasone; nasal
1.9
7.2
144
962
M75.5
ICD-10 Finland
Bursitis of shoulder
12.4
7.1
12
10
M53.1
ICD-10 Finland
Cervicobrachial syndrome
3.0
7.0
40
145
SPAT1260
SPAT
Consultation of another employee
2.4
7.0
59
272
N06AX21
ATC
duloxetine; oral
3.2
7.0
36
123
J01CA04
ATC
amoxicillin; systemic
2.1
6.9
244
1992
S18
ICPC
Laceration/cut
2.0
6.9
125
799
M77.1
ICD-10 Finland
Lateral epicondylitis
4.1
6.8
25
65
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.1
6.8
36
126
K02.1
ICD-10 Finland
Caries of dentine
1.9
6.7
167
1195
NBT60
NOMESCO Finland
Forcible manipulation of humeroscapular joint
23.1
6.7
9
*
SAA02
NOMESCO Finland
Basic examination of mouth
1.9
6.7
191
1430
J01DA01
ATC
[U] cefalexin; systemic
1.9
6.7
194
1462
J01AA02
ATC
doxycycline; systemic
2.1
6.6
244
2002
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
12.6
6.6
11
9
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
6.6
100
595
R07.4
ICD-10 Finland
Chest pain, unspecified
2.1
6.6
82
450
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.2
6.6
69
353
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.9
6.5
149
1031
M76.6
ICD-10 Finland
Achilles tendinitis
6.2
6.4
16
27
J45.9
ICD-10 Finland
Asthma, unspecified
2.4
6.4
57
269
A02BC02
ATC
pantoprazole; systemic
1.9
6.4
195
1484
A02BC05
ATC
esomeprazole; systemic
1.9
6.3
124
811
R03AC02
ATC
salbutamol; inhalant
1.8
6.3
157
1113
M72.0
ICD-10 Finland
Palmar fascial fibromatosis [Dupuytren]
18.5
6.3
9
5
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.8
6.3
168
1218
R03DC03
ATC
montelukast; oral
2.4
6.3
54
250
NBL50
NOMESCO Finland
Tenolysis or tenosynovectomy of shoulder or upper arm
+∞
6.3
6
*
NB1ZT
NOMESCO Finland
Crushing of soft tissue calcifications in shoulder wiht ultrasound quidance
+∞
6.3
6
*
H02BX01
ATC
methylprednisolone, combinations; systemic
4.4
6.3
21
50
WX204
NOMESCO Finland
Axillary plexus blockaced
6.5
6.2
15
24
WX400
NOMESCO Finland
Inhalation anesthesy
4.9
6.2
19
41
P01AB01
ATC
metronidazole; oral, rectal
1.9
6.2
128
851
M02AA10
ATC
ketoprofen; topical
2.4
6.1
54
254
M65.4
ICD-10 Finland
Radial styloid tenosynovitis [de Quervain]
12.9
6.1
10
8
M54.6
ICD-10 Finland
Pain in thoracic spine
3.5
6.1
27
83
Mortality – FinRegistry
↥Association
Association between endpoint M13_CALCTENDINITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_CALCTENDINITIS | 0.851 [0.67, 1.07] | 0.175 |
| Birth year | 0.995 [0.99, 1.0] | 0.238 |
During the follow-up period (1.1.1998 — 31.12.2019), 71 out of 1127 females with M13_CALCTENDINITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_CALCTENDINITIS | 0.862 [0.68, 1.09] | 0.209 |
| Birth year | 0.988 [0.98, 1.0] | 0.029 |
During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 721 males with M13_CALCTENDINITIS died.
Mortality risk
Mortality risk for people of age
years, who have M13_CALCTENDINITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.077% | 0.162% |
| 5 | 0.494% | 0.958% |
| 10 | 1.316% | 2.609% |
| 15 | 2.429% | 4.989% |
| 20 | 4.252% | 8.412% |
Relationships between endpoints
↥Index endpoint: M13_CALCTENDINITIS – Calcific tendinitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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