Calcific tendinitis

M13_CALCTENDINITIS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M65.2
  • Cause of death: ICD-10 M65.2

2 out of 7 registries used, show all original rules.

355

4. Check minimum number of events

None

355

5. Include endpoints

None

355

6. Filter based on genotype QC (FinnGen only)

344

Control definitions (FinnGen only)

Control exclude
M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M65
Name in latin
Tendinitis calcificans

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2142 1286 852
Only index persons 2086 1262 824
Unadjusted period prevalence (%)
Whole population 0.03 0.04 0.02
Only index persons 0.04 0.05 0.03
Median age at first event (years)
Whole population 50.24 50.75 49.52
Only index persons 50.18 50.65 49.47

-FinnGen-

Key figures

All Female Male
Number of individuals 344 215 129
Unadjusted period prevalence (%) 0.07 0.08 0.06
Median age at first event (years) 52.66 50.34 56.53

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
355
Matched controls
3550
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M65.2
ICD-10 Finland
Calcific tendinitis
4503599627370496.0
307.7
354
*
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
57.2
126.8
73
16
M75.1
ICD-10 Finland
Rotator cuff syndrome
8.7
91.1
166
324
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
29.9
84.7
58
23
M75.3
ICD-10 Finland
Calcific tendinitis of shoulder
303.5
52.6
52
*
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
10.0
34.9
42
47
M79.6
ICD-10 Finland
Pain in limb
3.7
33.2
179
759
N02AX02
ATC
tramadol; systemic, rectal
3.6
31.7
197
909
NBG10
NOMESCO Finland
Acromioplastia
77.3
31.5
35
5
M65.3
ICD-10 Finland
Trigger finger
11.6
28.1
30
28
N03AX12
ATC
[U] gabapentin; oral
4.2
26.2
85
250
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
93.3
24.0
26
*
N03AX16
ATC
[U] pregabalin
3.4
23.9
111
414
M01AH05
ATC
etoricoxib; oral
3.4
22.7
266
1670
M19.0
ICD-10 Finland
Primary arthrosis of other joints
4.7
22.4
57
138
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.9
22.0
191
1010
M01AH01
ATC
celecoxib; oral
3.6
21.9
90
309
M54.4
ICD-10 Finland
Lumbago with sciatica
3.6
21.5
85
284
G56.0
ICD-10 Finland
Carpal tunnel syndrome
4.1
21.4
68
195
L08
ICPC
Shoulder symptom/complaint
3.3
20.4
95
351
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
29.1
20.3
27
10
M03BX02
ATC
tizanidine; oral
3.1
20.0
262
1691
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
3.8
20.0
71
220
M79.0
ICD-10 Finland
Rheumatism, unspecified
74.0
18.9
21
*
M25.5
ICD-10 Finland
Pain in joint
2.8
18.4
136
647
Z01.8
ICD-10 Finland
Other specified special examinations
3.0
17.8
104
436
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
7.2
17.7
27
40
M02AA07
ATC
piroxicam; topical
2.7
17.4
149
759
NBF25
NOMESCO Finland
Operation for humeroscapular osteochondritis, arthroscopic
37.1
16.9
21
6
NHL16
NOMESCO Finland
Tenolysis or tenosynovectomy of achilles tendon
+∞
16.8
16
*
M01AB05
ATC
diclofenac; systemic, rectal
2.8
16.3
266
1828
M70.6
ICD-10 Finland
Trochanteric bursitis
3.6
16.0
58
181
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.8
15.9
53
156
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
5.4
15.6
32
64
M48.0
ICD-10 Finland
Spinal stenosis
3.7
15.5
54
164
M67.4
ICD-10 Finland
Ganglion
6.3
15.5
27
46
H02AB06
ATC
prednisolone; systemic
2.4
15.2
187
1112
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
16.0
15.1
24
16
M54.5
ICD-10 Finland
Low back pain
2.5
14.9
139
727
M01AX17
ATC
nimesulide; oral
2.7
14.8
102
461
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
4.1
14.4
42
112
N02AJ06
ATC
codeine and paracetamol; systemic
2.4
14.1
165
951
A02BC03
ATC
lansoprazole; oral
2.5
13.9
125
639
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.4
13.8
136
725
M75.2
ICD-10 Finland
Bicipital tendinitis
15.5
13.8
22
15
A02BC01
ATC
omeprazole; systemic
2.5
13.4
111
546
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
4.2
13.3
37
95
M53.1
ICD-10 Finland
Cervicobrachial syndrome
3.3
13.3
54
181
M03BC01
ATC
orphenadrine (citrate); systemic
2.6
13.1
99
466
M01AB55
ATC
diclofenac, combinations; oral
4.2
12.9
36
93
M01AE02
ATC
naproxen; oral, rectal
2.3
12.9
216
1432
M01AC06
ATC
meloxicam; systemic, rectal
2.3
12.6
147
837
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.8
12.2
70
286
ACC51
NOMESCO Finland
Release of median nerve
4.1
11.9
34
89
N06AX21
ATC
duloxetine; oral
3.3
11.8
49
166
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.4
11.7
45
145
UJF32
NOMESCO Finland
Coloscopy
2.4
11.6
108
555
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.3
11.4
114
603
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
2.1
11.1
175
1110
N02BE01
ATC
paracetamol; systemic, rectal
3.6
10.9
327
2709
M01AE03
ATC
ketoprofen; systemic, rectal
2.2
10.8
144
853
L03
ICPC
Low back symptom/complaint
2.3
10.8
99
504
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
4.7
10.7
25
56
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
8.6
10.5
22
27
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.3
10.4
95
481
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
33.6
10.4
13
*
M02AA10
ATC
ketoprofen; topical
2.6
10.4
68
296
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
4.0
10.1
30
81
L13
ICPC
Hip symptom/complaint
2.5
10.0
73
334
J01FA06
ATC
roxithromycin; oral
2.1
9.9
152
943
M75.9
ICD-10 Finland
Shoulder lesion, unspecified
5.1
9.9
21
43
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
4.5
9.7
24
56
NBT60
NOMESCO Finland
Forcible manipulation of humeroscapular joint
56.6
9.7
11
*
NDM10
NOMESCO Finland
Palmar fasciotomy of hand
56.6
9.7
11
*
WX400
NOMESCO Finland
Inhalation anesthesy
4.1
9.6
27
70
N06AA09
ATC
amitriptyline; systemic
3.1
9.5
42
147
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
5.1
9.4
20
41
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
4.0
9.4
27
71
NB1ZT
NOMESCO Finland
Crushing of soft tissue calcifications in shoulder wiht ultrasound quidance
+∞
9.4
9
*
N02BF01
ATC
gabapentin; oral
3.5
9.3
33
101
A02BC02
ATC
pantoprazole; systemic
2.1
9.3
250
1884
WX204
NOMESCO Finland
Axillary plexus blockaced
5.2
9.2
19
38
M54.2
ICD-10 Finland
Cervicalgia
3.2
9.2
37
123
R07.4
ICD-10 Finland
Chest pain, unspecified
2.1
9.1
105
581
A02BC05
ATC
esomeprazole; systemic
2.0
9.1
151
958
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
2.3
9.0
82
412
M13.9
ICD-10 Finland
Arthritis, unspecified
3.6
9.0
31
93
SPAT1263
SPAT
Sampling
2.0
9.0
149
944
M79.7
ICD-10 Finland
Fibromyalgia
13.0
8.9
15
12
M54.8
ICD-10 Finland
Other dorsalgia
5.0
8.7
19
40
R03AC02
ATC
salbutamol; inhalant
1.9
8.6
199
1406
P01AB01
ATC
metronidazole; oral, rectal
2.0
8.6
157
1025
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.1
8.5
109
626
M54.6
ICD-10 Finland
Pain in thoracic spine
3.2
8.5
35
118
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
8.4
98
543
X59
ICD-10 Finland
Exposure to unspecified factor
2.4
8.4
66
311
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
8.4
159
1048
R52.9
ICD-10 Finland
Pain, unspecified
2.9
8.3
40
147
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.9
8.3
203
1452
SPAT1260
SPAT
Consultation of another employee
2.3
8.3
68
327
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.6
8.3
28
83
R42
ICD-10 Finland
Dizziness and giddiness
2.2
8.3
83
434
J01DB01
ATC
cefalexin; oral
2.3
8.3
296
2425
SPAT1153
SPAT
Removal of sutures
2.0
8.2
116
689
S18
ICPC
Laceration/cut
1.9
8.2
164
1097
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.1
8.2
36
126
XA402
NOMESCO Finland
ENMG
9.3
8.1
16
18
R01AD09
ATC
mometasone; nasal
1.9
8.1
171
1164
G01AF01
ATC
metronidazole; vaginal
2.6
8.0
50
212
R01AD08
ATC
fluticasone; nasal
2.0
8.0
110
648
H02BX01
ATC
methylprednisolone, combinations; systemic
4.0
7.9
23
61
M77.1
ICD-10 Finland
Lateral epicondylitis
3.3
7.9
31
101
SAA01
NOMESCO Finland
Simple examination of mouth
2.0
7.8
255
1991
SPAT1254
SPAT
Administration of medicine
2.6
7.8
50
214
SPAT1216
SPAT
Assessment of functional ability
2.5
7.7
54
241
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
7.7
147
964
A06AC01
ATC
ispaghula (psylla seeds); oral
2.0
7.7
99
568
TDM10
NOMESCO Finland
Puncture of maxillary antrum
4.3
7.6
20
49
WX200
NOMESCO Finland
Interscalenous plexus blockade
12.2
7.6
13
11
J01DA01
ATC
[U] cefalexin
1.9
7.6
218
1625
J01AA02
ATC
doxycycline; systemic
2.1
7.4
284
2323
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.2
7.4
68
342
RF410, ,
NOMESCO Finland
11.2
7.4
13
12
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
2.9
7.3
36
134
M79.1
ICD-10 Finland
Myalgia
2.6
7.3
46
195
7261A
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Rotator cuff syndrome of shoulder and allied disorders[TENDINITIS CALCIFICANS HUMEROSCAPULARIS]
+∞
7.3
7
*
J45.9
ICD-10 Finland
Asthma, unspecified
2.2
7.3
71
365
M47.82
ICD-10 Finland
Other spondylosis, cervical region
4.5
7.3
18
42
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
3.0
7.3
34
123
L12
ICPC
Hand/finger symptom/complaint
2.3
7.3
59
281
M75.5
ICD-10 Finland
Bursitis of shoulder
7.6
7.3
16
22
M01AB08
ATC
etodolac; oral
3.0
7.3
32
112
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.9
7.3
120
748
-1, ,
NOMESCO Finland
1.9
7.2
117
724
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.0
7.2
33
118
SPAT1325
SPAT
Vaccination
1.9
7.2
113
692
M01AE11
ATC
tiaprofenic acid; oral, rectal
4.2
7.2
19
47
M01AX01
ATC
nabumetone; oral
4.2
7.2
19
47
9242
FHL
Other reconstruction or plastic surgery of shoulder joint (including ac joint)
20.5
7.2
10
5
RF420, ,
NOMESCO Finland
10.3
7.1
13
13
SFA20
NOMESCO Finland
Two-surface restoration
1.8
7.1
213
1596
SFA10
NOMESCO Finland
One-surface restoration
1.8
7.0
197
1446
R01BA52
ATC
pseudoephedrine, combinations; oral
1.9
7.0
121
765
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.6
6.9
41
169
M70.7
ICD-10 Finland
Other bursitis of hip
8.5
6.9
14
17
J01FF01
ATC
clindamycin; systemic
2.0
6.9
97
572
SPAT1310
SPAT
Counselling related to known health issue
1.9
6.9
109
669
SAA03
NOMESCO Finland
Extended examination of mouth
1.8
6.8
137
905
SPAT1249
SPAT
Treatment-related counselling outside office
1.8
6.8
132
862
RF210, ,
NOMESCO Finland
4.4
6.8
17
40
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.0
6.8
30
105
R03BA08
ATC
ciclesonide; inhalant
2.6
6.8
40
164
M76.6
ICD-10 Finland
Achilles tendinitis
4.0
6.8
19
49
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.2
6.8
27
89
J01CA04
ATC
amoxicillin; systemic
2.1
6.7
287
2386
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
6.7
103
625
M76.0
ICD-10 Finland
Gluteal tendinitis
8.0
6.7
14
18
RD211, ,
NOMESCO Finland
3.5
6.7
23
69
N02BF02
ATC
pregabalin; oral
3.5
6.7
23
69
R01AD58
ATC
fluticasone, combinations; nasal
2.0
6.7
90
522
G44.2
ICD-10 Finland
Tension-type headache
2.3
6.7
51
237
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
4.3
6.6
17
41
WX720
NOMESCO Finland
Own respiration
3.4
6.5
24
75
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
3.0
6.5
29
102
R05DA01
ATC
ethylmorphine; oral
2.7
6.5
35
137
SPAT1192
SPAT
Gynaecological examination
3.2
6.5
26
86
R21
ICPC
Throat symptom/complaint
2.1
6.5
65
338
R03DC03
ATC
montelukast; oral
2.1
6.4
63
325
XCK00
NOMESCO Finland
Perimetry
3.1
6.4
26
87
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.0
6.4
75
414
R06AE07
ATC
cetirizine; oral
1.8
6.3
152
1055
M01AH02
ATC
rofecoxib; oral
2.5
6.3
42
183
NBL50
NOMESCO Finland
Tenolysis or tenosynovectomy of shoulder or upper arm
+∞
6.3
6
*
C07AB07
ATC
bisoprolol; oral
1.8
6.3
168
1202
SFA00
NOMESCO Finland
Small restoration
2.2
6.3
54
264
NDA30
NOMESCO Finland
Exploration of joint of wrist or hand, arthroscopic
27.2
6.3
8
*
S29
ICPC
Skin symptom/complaint other
2.1
6.2
65
343
R03BA01
ATC
beclometasone; inhalant
2.3
6.2
52
251
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
2.3
6.2
50
238
J02AC01
ATC
fluconazole; systemic
1.8
6.2
145
998
R74
ICPC
Upper respiratory infection acute
1.8
6.1
105
658
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.1
6.0
62
325

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
120
687
2.13
9.65
2.8
2.5
333.59
10437.90
umol/l
4.41
107
600
83
412
2.32
9.45
1.3
1.2
5.04
20.42
u/ml
1.80
43
164
87
449
2.24
9.00
1.3
1.2
25.08
39.38
iu/ml
0.77
25
166
266
2064
2.15
8.95
4.9
3.5
11.76
11.65
mm/h
0.05
255
1910
280
2230
2.21
8.60
4.2
3.8
14.80
14.69
pmol/l
0.27
258
2033
277
2226
2.11
7.87
6.3
7.7
72.16
79.73
u/l
3.54
265
2108
182
1326
1.76
6.42
3.8
3.2
0.00
0.00
estimate
0.50
43
245
327
2886
2.69
6.28
14.1
12.6
21.01
24.03
mg/l
0.84
267
2220
311
2697
2.24
6.02
5.2
4.4
1.99
1.91
mu/l
0.57
289
2465
44
203
2.33
5.83
1.5
1.5
—
—
—
0
0
181
1341
1.71
5.82
4.8
4.4
0.00
0.00
estimate
-0.00
42
234
183
1360
1.71
5.82
3.8
3.2
0.00
0.00
estimate
-0.00
41
224
58
303
2.09
5.68
1.9
2.4
239.30
138.48
ug/g
0.37
42
254
149
1059
1.70
5.50
3.3
3.0
5.80
5.87
ph
—
10
106
106
685
1.78
5.48
4.6
3.4
0.00
0.00
estimate
0.50
41
227
317
2800
2.23
5.37
6.6
5.3
40.91
39.50
mmol/mol
1.57
297
2608
334
3035
2.70
4.97
4.9
4.3
4.67
4.79
mmol/l
1.33
310
2842
234
1904
1.67
4.92
4.3
3.7
—
—
—
0
0
340
3121
3.12
4.89
14.6
11.8
—
—
—
0
0
201
1584
1.62
4.71
4.6
4.9
6.75
6.67
mmol/l
0.20
189
1491
332
3022
2.52
4.67
4.8
4.3
1.44
1.51
mmol/l
2.30
310
2810
178
1365
1.61
4.65
6.4
7.1
1.22
1.21
mmol/l
0.21
146
1166
123
863
1.65
4.59
2.5
2.3
53.00
66.53
u/l
1.60
113
804
88
569
1.73
4.45
4.3
3.5
1.02
1.02
kg/l
0.24
13
85
336
3090
2.63
4.35
5.3
4.8
2.74
2.85
mmol/l
1.43
311
2873
181
1416
1.57
4.20
5.6
5.3
2.02
1.91
e9/l
0.61
165
1252
112
783
1.63
4.18
2.4
2.0
186.69
283.75
u/l
0.44
101
734
324
2949
2.13
4.06
4.8
4.3
6.20
5.90
mmol/l
2.10
295
2720
322
2925
2.08
4.04
4.4
3.9
1.43
1.29
mmol/l
2.05
300
2708
56
327
1.85
3.96
1.3
1.3
1268.57
419.38
titre
—
7
64
37
188
2.08
3.90
3.5
3.6
—
—
—
0
0
28
127
2.31
3.88
1.2
1.3
—
—
—
0
0
166
1293
1.53
3.81
5.9
6.0
—
—
—
0
0
148
1126
1.54
3.77
2.4
2.2
80.08
77.28
nmol/l
0.56
133
1029
334
3091
2.36
3.76
15.2
14.5
3.95
3.97
mmol/l
0.37
329
3014
175
1390
1.51
3.60
5.5
5.3
0.61
0.57
e9/l
0.97
157
1197
85
575
1.63
3.56
1.2
1.2
1.44
2.01
u/ml
0.23
32
153
175
1393
1.51
3.55
5.5
5.3
0.04
0.04
e9/l
0.70
158
1202
179
1433
1.50
3.52
5.8
5.8
0.22
0.18
e9/l
2.00
162
1258
60
373
1.73
3.45
1.2
1.2
—
—
—
0
0
341
3200
2.66
3.43
10.8
9.8
27.95
26.29
u/l
0.77
332
3089
32
163
2.06
3.36
4.2
8.1
—
—
—
0
0
348
3332
3.25
3.32
20.9
18.6
39.90
40.41
%
0.64
320
3099
133
1011
1.50
3.31
4.5
3.3
93.16
30.77
ng/l
0.44
91
686
154
1207
1.49
3.30
4.1
4.7
36.14
35.77
g/l
0.41
143
1142
156
1226
1.49
3.29
5.1
6.2
1.21
1.22
mmol/l
0.04
135
1128
50
301
1.77
3.21
2.2
1.5
—
—
—
0
0
348
3336
3.19
3.18
21.2
18.5
4.49
4.50
e12/l
0.27
341
3247
348
3335
3.20
3.18
21.0
18.5
258.37
252.25
e9/l
1.15
343
3253
348
3334
3.22
3.17
21.2
18.5
6.92
6.49
e9/l
3.88
341
3245
83
577
1.57
3.08
1.9
1.7
1.00
1.20
mg/l
0.42
65
442
82
569
1.57
3.07
3.6
3.3
—
—
—
0
0
37
206
1.89
3.05
4.1
4.4
0.00
0.13
%
—
8
60
13
46
2.90
2.95
1.2
1.2
479.31
422.23
mg/l
0.27
13
40
38
216
1.85
2.94
4.0
4.3
0.00
0.16
%
—
8
69
180
1486
1.43
2.80
4.7
7.1
10.21
11.41
umol/l
1.22
170
1427
40
235
1.79
2.79
3.9
4.2
0.55
1.32
%
—
10
88
37
213
1.82
2.76
3.5
4.1
0.40
0.77
%
—
10
72
163
1329
1.42
2.68
5.6
5.2
56.44
56.88
%
0.20
150
1244
164
1346
1.41
2.57
5.8
5.4
29.65
28.02
%
1.19
153
1262
17
78
2.24
2.35
1.2
1.1
—
—
—
0
0
77
559
1.48
2.31
1.7
1.7
104687928.69
8282002.85
pmol/l
0.44
64
483
102
782
1.43
2.31
3.6
2.8
—
—
—
0
0
159
1318
1.37
2.27
6.2
5.6
8.40
8.73
%
0.66
148
1234
11
41
2.74
2.22
2.2
1.5
115.10
1428.56
u/l
—
5
17
158
1312
1.37
2.21
5.6
5.3
2.93
2.80
%
0.35
147
1229
154
1275
1.37
2.19
8.3
11.4
1.22
1.24
inr
0.06
43
381
8
24
3.39
2.19
1.0
1.0
—
—
—
0
0
45
296
1.60
2.11
3.8
9.9
2.14
1.02
mmol/l
1.22
34
240
153
1275
1.35
2.06
10.6
8.7
0.00
0.00
e9/l
0.02
135
1040
240
2142
1.37
2.06
4.1
3.5
—
—
—
0
0
152
1266
1.35
2.05
5.4
5.3
0.79
0.71
%
1.09
141
1179
27
156
1.79
2.03
2.8
2.3
36.16
19.99
au/ml
—
5
8
153
1278
1.35
2.02
2.6
2.5
—
—
—
0
0
223
1971
1.35
2.01
3.1
2.9
54.75
53.53
u/l
0.06
205
1853
190
1642
1.34
1.98
7.3
9.7
4.32
3.98
e9/l
1.07
173
1434
9
33
2.77
1.94
3.0
3.2
3.41
4.07
e9/l
—
9
33
45
304
1.55
1.90
1.6
1.5
—
—
—
0
0
8
28
2.90
1.87
1.5
1.3
—
—
—
0
0
16
80
2.05
1.83
1.3
1.4
387.90
317.10
ug/g
—
10
45
104
831
1.36
1.80
3.4
3.1
54.08
283.65
mg/l
1.00
79
534
63
462
1.44
1.80
1.9
1.7
1197.25
1187.90
nmol/l
0.03
51
351
70
524
1.42
1.79
2.8
2.3
7.67
6.99
e6/l
0.11
65
469
9
36
2.54
1.75
1.0
1.3
—
—
—
0
0
9
36
2.54
1.75
3.8
3.3
54.00
55.89
%
—
9
36
16
289
0.53
1.70
2.1
1.4
—
—
—
0
0
28
175
1.65
1.63
1.3
1.3
—
—
—
0
0
109
890
1.32
1.62
3.9
3.6
15.20
7.41
mg/mmol
0.70
84
556
107
872
1.33
1.61
3.4
3.0
7.66
7.70
mmol/l
0.03
98
743
49
350
1.46
1.61
3.1
2.3
23.12
23.31
%
0.03
41
307
8
32
2.53
1.60
1.1
1.3
—
—
—
0
0
5
15
3.36
1.53
1.2
1.1
—
—
—
0
0
87
693
1.34
1.52
2.5
2.6
—
—
—
0
0
39
269
1.51
1.52
1.4
1.5
—
—
—
0
0
279
2596
1.35
1.52
15.1
15.1
15.39
14.80
%
0.75
274
2547
22
134
1.68
1.43
2.5
2.4
—
—
—
0
0
43
309
1.45
1.38
1.3
1.3
—
—
—
0
0
101
833
1.30
1.38
4.6
3.5
—
—
—
0
0
16
90
1.81
1.35
6.1
3.8
—
—
—
0
0
112
939
1.28
1.34
2.9
3.9
2.35
2.36
mmol/l
0.30
100
847
9
44
2.07
1.27
1.8
3.7
—
—
—
0
0
9
44
2.07
1.27
1.3
1.2
—
—
—
0
0
36
256
1.45
1.24
4.5
4.5
—
—
—
0
0
8
37
2.19
1.22
1.3
1.7
—
—
—
0
0
13
71
1.86
1.21
1.5
1.3
0.20
0.25
g/l
1.37
13
66
0
36
0.00
1.14
0.0
1.1
—
—
—
0
0
11
58
1.93
1.13
1.6
1.8
—
—
—
0
0
29
406
0.69
1.12
1.4
1.2
—
—
—
0
0
136
1191
1.23
1.09
2.8
2.5
136.20
140.48
ug/l
0.07
127
1103
18
113
1.62
1.08
3.0
4.0
—
—
—
0
0
7
33
2.14
1.06
1.9
1.9
1.39
1.65
mmol/l
—
7
33
13
75
1.76
1.04
1.3
1.1
—
—
—
0
0
26
180
1.48
1.04
3.2
3.5
4.28
8.56
e9/l
0.71
18
150
47
363
1.34
1.03
2.1
1.8
—
—
—
0
0
7
35
2.02
1.00
1.3
1.1
—
—
—
0
0
5
23
2.19
0.98
1.2
1.2
—
—
—
0
0
0
31
0.00
0.97
0.0
1.7
—
—
—
0
0
20
133
1.53
0.96
1.1
1.1
—
111.67
—
0
6
6
27
2.24
0.94
1.0
1.0
—
—
—
0
0
46
360
1.32
0.93
2.5
2.2
—
—
—
0
0
15
94
1.62
0.92
2.7
4.3
0.24
0.21
g/l
—
6
41
123
1083
1.21
0.92
2.0
1.9
105.90
95.10
pmol/l
1.58
68
555
74
618
1.25
0.91
2.6
1.9
2.99
3.17
mg/l
0.31
69
521
62
507
1.27
0.91
3.5
3.6
308.35
366.99
ng/l
0.09
48
393
6
32
1.89
0.82
3.0
3.6
4.17
3.59
nmol/l
—
6
32
101
882
1.20
0.81
4.3
4.7
15.93
2.67
ug/l
0.47
80
793
8
47
1.72
0.81
2.1
2.7
—
—
—
0
0
96
839
1.20
0.77
3.3
3.9
7.39
7.40
ph
0.42
25
160
28
210
1.36
0.76
2.7
2.8
67.99
69.31
e9/l
0.08
21
160
62
519
1.24
0.76
1.5
1.6
2.63
2.39
g/l
0.34
45
336
132
1189
1.18
0.75
1.8
2.0
—
—
—
0
0
5
24
2.10
0.75
3.8
2.7
—
—
—
0
0
21
151
1.42
0.73
3.8
14.7
—
—
—
0
0
90
786
1.19
0.73
2.6
2.6
—
—
—
0
0
16
109
1.49
0.72
1.1
1.1
—
—
—
0
0
5
26
1.94
0.71
2.4
2.5
—
—
—
0
0
66
768
0.83
0.69
1.3
1.3
—
—
—
0
0
15
102
1.49
0.68
1.7
1.6
—
—
—
0
0
26
197
1.35
0.68
1.2
1.1
—
—
—
0
0
60
508
1.22
0.67
3.0
2.6
562.44
558.38
mosm/kgh2o
0.05
54
439
5
29
1.73
0.64
1.0
1.2
—
—
—
0
0
11
163
0.66
0.61
1.7
2.6
28.69
49.74
u/ml
0.49
11
158
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
22
166
1.35
0.60
2.7
3.1
—
—
—
0
0
0
22
0.00
0.59
0.0
15.1
—
806.09
—
0
22
0
22
0.00
0.59
0.0
20.7
—
1443.18
—
0
22
7
111
0.62
0.59
1.4
1.6
—
—
—
0
0
82
725
1.17
0.58
2.7
2.7
0.63
0.73
e6/l
0.15
66
544
25
318
0.77
0.58
1.9
2.5
19.71
8.61
umol/l
0.38
17
275
5
87
0.57
0.57
1.4
1.2
—
—
—
0
0
33
267
1.26
0.56
2.0
1.6
—
—
—
0
0
6
39
1.55
0.53
1.2
1.1
—
—
—
0
0
11
75
1.48
0.51
1.6
2.9
—
—
—
0
0
15
110
1.38
0.49
1.7
1.6
1.40
1.57
g/l
0.31
15
97
102
929
1.14
0.49
3.6
3.2
74.90
67.51
e6/l
0.09
74
659
7
47
1.50
0.48
1.4
1.3
—
—
—
0
0
88
797
1.14
0.46
3.2
2.8
74.93
155.13
e6/l
0.38
68
615
28
230
1.24
0.44
1.4
1.3
—
—
—
0
0
19
150
1.28
0.41
4.1
10.3
94.60
93.38
%
0.84
19
150
0
17
0.00
0.40
0.0
1.8
—
—
—
0
0
24
196
1.24
0.40
1.0
1.3
24.34
141.78
iu/ml
—
7
89
5
35
1.43
0.39
3.0
2.9
—
—
—
0
0
5
36
1.39
0.38
1.0
1.6
—
—
—
0
0
12
158
0.75
0.38
1.8
1.6
—
—
—
0
0
9
70
1.29
0.37
3.0
1.5
—
—
—
0
0
9
70
1.29
0.37
3.6
1.5
—
—
—
0
0
9
71
1.27
0.36
3.0
1.5
—
—
—
0
0
9
71
1.27
0.36
3.1
1.5
—
—
—
0
0
6
43
1.40
0.35
2.5
2.0
—
—
—
0
0
35
303
1.17
0.34
2.0
1.5
—
—
—
0
0
6
46
1.31
0.33
2.5
2.8
102.17
105.04
mmol/l
—
6
46
6
46
1.31
0.33
2.5
2.8
3.80
4.00
mmol/l
—
6
46
38
335
1.15
0.30
1.6
1.4
—
—
—
0
0
26
222
1.18
0.30
2.4
2.2
11.36
7.81
ug/l
0.32
21
201
38
425
0.88
0.27
2.4
2.5
8.99
2.27
e6/l
0.83
21
237
8
65
1.24
0.27
2.6
5.3
—
—
—
0
0
8
65
1.24
0.27
3.3
1.5
—
—
—
0
0
8
67
1.20
0.26
1.1
1.2
—
—
—
0
0
16
133
1.21
0.24
2.4
3.4
—
—
—
0
0
12
97
1.25
0.23
12.2
7.7
—
—
—
0
0
5
41
1.22
0.22
1.6
1.9
31.40
33.27
pg
—
5
41
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
2.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
6
49
1.23
0.20
1.2
1.1
—
—
—
0
0
6
50
1.20
0.20
1.2
1.1
—
—
—
0
0
18
207
0.86
0.19
3.2
3.2
9.62
10.60
g/l
0.48
18
192
15
128
1.18
0.18
1.9
1.3
32.92
32.75
iu/l
0.01
15
108
8
69
1.16
0.16
1.1
1.1
—
—
—
0
0
15
130
1.16
0.16
4.0
2.2
0.68
0.68
%
0.01
15
130
9
78
1.16
0.15
1.9
4.0
—
—
—
0
0
15
133
1.13
0.12
4.0
2.3
1.17
1.16
%
0.00
15
133
32
343
0.93
0.12
1.4
1.4
—
—
—
0
0
15
134
1.12
0.11
1.1
1.1
—
—
—
0
0
5
44
1.14
0.10
5.4
3.7
—
—
—
0
0
5
44
1.14
0.10
2.8
2.8
—
—
—
0
0
6
55
1.09
0.09
2.3
1.9
—
—
—
0
0
6
58
1.04
0.08
1.5
1.9
5.64
4.84
mmol/24h
—
6
52
6
72
0.83
0.07
1.0
1.1
—
—
—
0
0
6
75
0.80
0.07
3.0
2.6
1.28
1.53
mg/l
—
6
68
10
112
0.89
0.07
3.0
2.5
—
—
—
0
0
67
690
0.96
0.07
5.9
7.5
—
—
—
0
0
17
183
0.93
0.06
1.8
1.8
—
—
—
0
0
73
712
1.03
0.06
4.7
4.0
—
—
—
0
0
19
178
1.07
0.06
1.7
1.5
—
—
—
0
0
89
874
1.02
0.04
2.1
2.3
—
—
—
0
0
23
224
1.03
0.00
4.9
3.0
—
—
—
0
0
51
516
0.99
0.00
2.4
2.9
0.70
0.74
ug/l
0.21
28
347
61
604
1.01
0.00
1.6
1.4
19.49
20.79
nmol/l
0.29
51
508
17
171
0.99
0.00
2.5
2.6
—
—
—
0
0
33
331
1.00
0.00
2.3
5.2
7.00
49.38
ug/l
1.01
26
274
121
1214
1.00
0.00
3.1
2.8
—
—
—
0
0
84
841
1.00
0.00
1.7
1.7
1.31
1.38
mmol/l
0.41
76
709
19
194
0.98
0.00
1.6
1.5
—
—
—
0
0
22
224
0.98
0.00
15.6
8.6
11.57
9.98
mmol/l
0.40
22
210
6
67
0.89
0.00
2.8
2.7
27.50
34.32
umol/l
—
6
60
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
-0.00
3.0
3.5
7.46
7.43
ph
—
6
48
0
5
0.00
-0.00
0.0
1.6
—
16.20
—
0
5
0
9
0.00
-0.00
0.0
2.8
—
6.30
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
6.21
—
0
5
6
64
0.94
-0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
3.26
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
22
220
1.00
-0.00
3.3
8.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
21.43
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_CALCTENDINITIS and mortality.

Females

Parameter HR [95% CI] p-value
M13_CALCTENDINITIS 0.851 [0.67, 1.07] 0.175
Birth year 0.995 [0.99, 1.0] 0.238

During the follow-up period (1.1.1998 — 31.12.2019), 71 out of 1127 females with M13_CALCTENDINITIS died.

Males

Parameter HR [95% CI] p-value
M13_CALCTENDINITIS 0.862 [0.68, 1.09] 0.209
Birth year 0.988 [0.98, 1.0] 0.029

During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 721 males with M13_CALCTENDINITIS died.

Mortality risk

Mortality risk for people of age

years, who have M13_CALCTENDINITIS.

N-year risk Females Males
1 0.077% 0.162%
5 0.494% 0.958%
10 1.316% 2.609%
15 2.429% 4.989%
20 4.252% 8.412%

Relationships between endpoints

Index endpoint: M13_CALCTENDINITIS – Calcific tendinitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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