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Right ventricular outflow tract obstruction

Endpoint Browser PheWeb

Q17_RVOTO

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — Q220|Q221|Q222|Q223|Q2240|Q2241|Q226|Q228|Q229|Q243|Q255|Q256
  • Hospital discharge: ICD-9 — 7460B|7460C|7460X|7461B|7461A|7468X|7468B|7473A
  • Hospital discharge: excluded ICD-10 — Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875
  • Hospital discharge: excluded ICD-9 — 758|7595|75683
  • Cause of death: ICD-10 — Q220|Q221|Q222|Q223|Q2240|Q2241|Q226|Q228|Q229|Q243|Q255|Q256
  • Cause of death: ICD-9 — 7460B|7460C|7460X|7461B|7461A|7468X|7468B|7473A
  • Cause of death: excluded ICD-10 — Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875
  • Cause of death: excluded ICD-9 — 758|7595|75683

2 out of 7 registries used, show all original rules.

305

4. Check minimum number of events

None

305

5. Include endpoints

None

305

6. Filter based on genotype QC (FinnGen only)

305

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF7

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4198 2225 1962
Only index persons 2655 1420 1235
Unadjusted period prevalence (%)
Whole population 0.06 0.06 0.05
Only index persons 0.05 0.05 0.05
Median age at first event (years)
Whole population 0.66 0.59 0.58
Only index persons 3.15 3.48 2.76

-FinnGen-

Key figures

All Female Male
Number of individuals 305 162 143
Unadjusted period prevalence (%) 0.06 0.06 0.06
Median age at first event (years) 5.09 6.79 3.17

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
287
Matched controls
2868
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q22.1
ICD-10 Finland
Congenital pulmonary valve stenosis
+∞
190.5
161
*
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
36.5
86.7
113
50
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
21.2
85.9
137
118
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
13.5
80.7
171
281
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
24.4
75.2
111
72
201
Kela drug reimbursment
Chronic cardiac insufficiency
46.9
74.8
91
28
XF400
NOMESCO Finland
ECG with 12 standard connections
10.6
66.7
160
304
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
39.1
61.7
78
27
C03DA01
ATC
spironolactone; oral
20.6
57.7
89
61
XF404
NOMESCO Finland
Ambulatory ECG
15.3
56.2
99
95
C03CA01
ATC
furosemide; systemic
12.9
54.3
105
123
XF402
NOMESCO Finland
ECG with work load test
18.4
51.7
83
62
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
55.5
49.5
58
13
31
HP
Congenital heart failure surgery
146.9
47.4
49
*
B01AA03
ATC
warfarin; systemic
15.7
47.3
81
70
I37.0
ICD-10 Finland
Pulmonary valve stenosis
+∞
47.2
44
*
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
49.2
46.8
56
14
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.4
46.4
176
569
FM2CE
NOMESCO Finland
NA
13.3
44.8
83
85
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
10.6
43.2
91
120
61
HP
Catheterization and pressure measurement of the left side of the heart
90.5
42.3
46
6
Q25.6
ICD-10 Finland
Stenosis of pulmonary artery
+∞
41.7
39
*
C01AA05
ATC
digoxin; systemic
33.8
40.8
53
19
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
48.1
37.5
45
11
Q22.0
ICD-10 Finland
Pulmonary valve atresia
+∞
37.3
35
*
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
51.6
37.1
44
10
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
112.3
36.7
39
*
TPH07
NOMESCO Finland
Cathetrisation of artery
7.9
35.9
91
159
62
HP
Catheterization and pressure measurement of the right side of the heart
136.5
34.5
36
*
7460C
ICD-9 Finland
Other congenital anomalies of heart, Anomalies of pulmonary valve[VITIUM VALVULAE PULMONALIS CONGENITA CUM STENOSIS]
+∞
32.9
31
*
I37.1
ICD-10 Finland
Pulmonary valve insufficiency
127.9
32.4
34
*
Q21.10
ICD-10 Finland
Persistent ostium secundum
17.4
32.0
51
35
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
6.4
31.8
95
205
WX408
NOMESCO Finland
General anesthesy, balanced
4.7
31.7
151
552
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
17.2
30.0
48
33
Q21.30
ICD-10 Finland
Tetralogy of Fallot
89.7
29.4
32
*
Q20.3
ICD-10 Finland
Discordant ventriculoarterial connection
115.3
29.3
31
*
XF622
NOMESCO Finland
Measurement of minute volume of heart
46.3
27.4
33
8
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
9.7
27.3
58
73
Q20.48
ICD-10 Finland
Single ventricle
107.0
27.2
29
*
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
29.2
26.9
36
14
Q20.1
ICD-10 Finland
Double outlet right ventricle
+∞
26.5
25
*
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
37.0
26.2
33
10
Q24.3
ICD-10 Finland
Pulmonary infundibular stenosis
+∞
25.4
24
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
7.8
24.0
58
90
XF600
NOMESCO Finland
Bloodpressure measurement
5.7
23.4
74
165
5255
FHL
Deep hypothermia (<20 °) with cardiopulmonary resuscitation
+∞
23.2
22
*
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
49.4
22.8
27
6
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.9
22.8
122
458
Z98.8
ICD-10 Finland
Other specified postsurgical states
17.9
22.5
35
22
74663
ICD-8 Finland
Congenital anomalies of heart, Stenosis valvulae pulmonalis
+∞
22.2
21
*
WX882
NOMESCO Finland
High dependency care
5.6
21.4
68
151
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
32.9
21.0
27
9
FBE32
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery
118.6
20.9
22
*
R4110
NOMESCO Finland
Physiotherapy
3.6
20.2
121
487
Q22.2
ICD-10 Finland
Congenital pulmonary valve insufficiency
+∞
20.0
19
*
FJF20
NOMESCO Finland
Replacement of pulmonary valve using homograft
112.8
19.8
21
*
C01BD01
ATC
amiodarone; systemic
49.7
19.5
23
5
XFE00
NOMESCO Finland
Epicardial ultrasonography
22.0
19.5
28
14
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
18.8
19.1
29
17
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
13.6
19.1
33
27
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
75.0
19.0
21
*
FBJ10
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery with interposition graft
202.5
18.8
19
*
Q22.41
ICD-10 Finland
Tricuspid atresia
+∞
17.9
17
*
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
17.4
17.4
27
17
FBE10
NOMESCO Finland
Expansion or reconstruction of pulmonary artery using patch
67.5
16.9
19
*
I37.2
ICD-10 Finland
Pulmonary valve stenosis with insufficiency
+∞
16.8
16
*
Q21.32
ICD-10 Finland
Pulmonary atresia with Fallot ventricular septal defect
+∞
16.8
16
*
Q87.14
ICD-10 Finland
Noonan's syndrome
179.8
16.7
17
*
WX872
NOMESCO Finland
Intensive care
11.8
15.9
29
27
G04BE03
ATC
sildenafil; oral
23.7
15.8
22
10
Q25.78
ICD-10 Finland
Other congenital malformations of pulmonary artery
90.0
15.7
17
*
FJD20
NOMESCO Finland
Bypass of pulmonary valve with ventriculopulmonary prosthesis or homograft
168.6
15.6
16
*
I48
ICD-10 Finland
Atrial fibrillation and flutter
6.9
15.4
39
64
TFP20
NOMESCO Finland
Cardiodefibrillation
11.0
15.3
29
29
207
Kela drug reimbursment
Chronic arrhythmias
8.0
15.3
35
49
FDF05
NOMESCO Finland
Percutaneous transluminal occlusion of aorto-pulmonary collaterals
47.7
15.2
18
*
TPH04
NOMESCO Finland
Cathetrisation of vein
3.5
15.1
82
297
FBE35
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery with insertion of stent
59.9
14.9
17
*
Q25.0
ICD-10 Finland
Patent ductus arteriosus
15.3
14.8
24
17
WX892
NOMESCO Finland
Monitored bed care
4.7
14.8
53
132
1EA01
NOMESCO Finland
NA
+∞
14.7
14
*
FJF10
NOMESCO Finland
Replacement of pulmonary valve using biological prosthesis
+∞
14.7
14
*
XQ903
NOMESCO Finland
Production of other scan or drawing
157.5
14.6
15
*
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
31.8
14.0
18
6
74734
ICD-8 Finland
Other congenital anomalies of circulatory system, Stenosis, hypoplasia sive aplasia arteriae pulmonalis
+∞
13.6
13
*
Q20.40
ICD-10 Finland
Double inlet left ventricle
+∞
13.6
13
*
ZX120
NOMESCO Finland
Intravenous
4.4
13.2
50
131
C07AA07
ATC
sotalol; systemic
17.8
13.2
20
12
Q21.19
ICD-10 Finland
Atrial septal defect NOS
33.7
12.7
16
5
7AX01
NOMESCO Finland
NA
21.2
12.6
18
9
Q22.3
ICD-10 Finland
Other congenital malformations of pulmonary valve
+∞
12.6
12
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
7.0
12.6
31
49
WX704
NOMESCO Finland
Intubation
5.3
12.5
39
83
Q25.41
ICD-10 Finland
Persistent right-sided aortic arch
39.4
12.3
15
*
ZX199
NOMESCO Finland
Other rote
14.2
12.1
20
15
FJE42
NOMESCO Finland
Percutaneous transluminal expansion of pulmonary valve
48.8
12.0
14
*
RS224
NOMESCO Finland
NA
10.3
12.0
23
24
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.2
11.8
68
251
Q22.40
ICD-10 Finland
Congenital tricuspid stenosis
+∞
11.5
11
*
7468X
ICD-9 Finland
Other congenital anomalies of heart, Other specified anomalies of heart[MUU SYDÄMEN EPÄMUODOSTUMA]
+∞
11.5
11
*
5253
FHL
Cardiac lung machine
124.7
11.5
12
*
I44.2
ICD-10 Finland
Atrioventricular block, complete
21.1
11.3
16
8
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.5
11.1
105
530
FPF20
NOMESCO Finland
Implantation of epicardial pacemaker with atrial and ventricular electrodes
45.1
11.0
13
*
C09AA02
ATC
enalapril; systemic
4.5
11.0
39
96
Q21.0
ICD-10 Finland
Ventricular septal defect
29.3
10.8
14
5
Q23.4
ICD-10 Finland
Hypoplastic left heart syndrome
29.3
10.8
14
5
Q24.0
ICD-10 Finland
Dextrocardia
113.9
10.5
11
*
FM1BD
NOMESCO Finland
Extensive CT of heart
113.9
10.5
11
*
FAE10
NOMESCO Finland
Bidirectional anastomosis between superior vena cava and pulmonary artery
113.9
10.5
11
*
Q22.6
ICD-10 Finland
Hypoplastic right heart syndrome
+∞
10.5
10
*
Q21.3
ICD-10 Finland
Tetralogy of Fallot
+∞
10.5
10
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.2
10.4
58
209
FAE00
NOMESCO Finland
Anastomosis to pulmonary artery from superior vena cava
33.9
10.4
13
*
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
7.7
10.2
23
32
I47.1
ICD-10 Finland
Supraventricular tachycardia
6.7
10.1
25
40
602
Kela drug reimbursment
Children's severe malnutrition
5.4
10.1
30
61
Z01.8
ICD-10 Finland
Other specified special examinations
2.8
9.9
74
320
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
31.1
9.5
12
*
FHB50
NOMESCO Finland
Transatrial closure of VSD using patch
22.6
9.4
13
6
FBA96
NOMESCO Finland
Other suture or repair of pulmonary artery
+∞
9.4
9
*
FAE30
NOMESCO Finland
Total cavo-pulmonary connection using fenestrated patch
+∞
9.4
9
*
7461A
ICD-9 Finland
Other congenital anomalies of heart, Tricuspid atresia and stenosis, congenital[VITIUM VALVULAE TRICUSPIDALIS CONGENITUM CUM ATRESI]
+∞
9.4
9
*
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
10.5
9.1
17
17
C07AB07
ATC
bisoprolol; oral
2.7
9.0
69
303
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
5.4
8.9
26
52
FFC22
NOMESCO Finland
Percutaneous transluminal closure of ostium secundum type ASD
14.6
8.8
14
10
3A077
NOMESCO Finland
NA
51.5
8.7
10
*
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
8.6
8.7
18
22
RD210
NOMESCO Finland
NA
4.1
8.6
33
88
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
28.4
8.5
11
*
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
28.4
8.5
11
*
XF620
NOMESCO Finland
Examination of circulation with color method
92.6
8.5
9
*
7452A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Tetralogy of Fallot[TETRALOGIA FALLOT]
+∞
8.4
8
*
Q21.31
ICD-10 Finland
Tetralogy of Fallot and double outlet right ventricle
+∞
8.4
8
*
Q25.5
ICD-10 Finland
Atresia of pulmonary artery
+∞
8.4
8
*
Q21.18
ICD-10 Finland
Other spedified atrial septal defect
+∞
8.4
8
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.7
8.4
63
273
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
5.2
8.3
25
52
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
17.8
8.1
12
7
FDA00
NOMESCO Finland
Aortoplasty and aorto-pulmonary shunt for HLHS
22.8
8.1
11
5
R07.4
ICD-10 Finland
Chest pain, unspecified
2.6
7.9
59
255
WX002
NOMESCO Finland
Sedation and analgesia
2.9
7.9
50
196
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
46.2
7.8
9
*
324
NOMESCO Finland
NA
46.2
7.8
9
*
FHE30
NOMESCO Finland
Repair of tetralogy of Fallot with transannular patch
46.2
7.8
9
*
WX402
NOMESCO Finland
General anaesthesia
2.3
7.7
83
432
Q25.1
ICD-10 Finland
Coarctation of aorta
10.4
7.6
14
14
AEX
HP
Other pulmonary or pulmonary artery valve procedure
82.0
7.4
8
*
Q24.9
ICD-10 Finland
Congenital malformation of heart, unspecified
82.0
7.4
8
*
Q20.8
ICD-10 Finland
Other congenital malformations of cardiac chambers and connections
82.0
7.4
8
*
FJD96
NOMESCO Finland
Other operation on right ventricle outlet for congenital or acquired obstruction
82.0
7.4
8
*
Q23.0
ICD-10 Finland
Congenital stenosis of aortic valve
13.8
7.4
12
9
Q22.8
ICD-10 Finland
Other congenital malformations of tricuspid valve
+∞
7.3
7
*
FBJ00
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery
+∞
7.3
7
*
7451B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[DOUBLE OUTLET RIGHT VENTRICLE]
+∞
7.3
7
*
7460B
ICD-9 Finland
Other congenital anomalies of heart, Anomalies of pulmonary valve[VITIUM VALVULAE PULMONALIS CONGENITUM CUM ATRESIA]
+∞
7.3
7
*
5504
FHL
Subclavian pulmonary anastomosis (Blalock)
+∞
7.3
7
*
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
3.5
7.2
33
103
Q24.4
ICD-10 Finland
Congenital subaortic stenosis
30.8
7.2
9
*
FEB10
NOMESCO Finland
Decompression and drainage of pericardium
20.6
7.2
10
5
I49.5
ICD-10 Finland
Sick sinus syndrome
12.4
7.1
12
10
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
9.1
7.1
14
16
ZX108
NOMESCO Finland
Inhalation
9.1
7.1
14
16
B34.9
ICD-10 Finland
Viral infection, unspecified
3.6
7.0
31
94
I47.2
ICD-10 Finland
Ventricular tachycardia
14.2
6.9
11
8
Z94.1
ICD-10 Finland
Heart transplant status
14.2
6.9
11
8
I50.9
ICD-10 Finland
Heart failure, unspecified
5.2
6.8
20
41
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
41.0
6.8
8
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.3
6.8
64
313
Q21.21
ICD-10 Finland
Atrioventricular duct
23.1
6.7
9
*
Q26.1
ICD-10 Finland
Persistent left superior vena cava
23.1
6.7
9
*
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.9
6.5
38
141
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
3.8
6.5
26
73
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.2
6.5
77
416
FFK20
NOMESCO Finland
Atrio-pulmonary anastomosis
71.3
6.4
7
*
7455A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ostium secundum type atrial septal defect
71.3
6.4
7
*
I28.8
ICD-10 Finland
Other specified diseases of pulmonary vessels
71.3
6.4
7
*
Q20.5
ICD-10 Finland
Discordant atrioventricular connection
71.3
6.4
7
*
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
71.3
6.4
7
*
FM1CD
NOMESCO Finland
Very extensive CT of heart
71.3
6.4
7
*
ZXA00
NOMESCO Finland
Right side
2.4
6.4
57
268
UGC02
NOMESCO Finland
Rigid bronchoscopy
8.4
6.4
13
16
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.8
6.4
26
74
7505
FHL
Funicular lysis and orchidopexy
18.5
6.3
9
5
R62.0
ICD-10 Finland
Delayed milestone
3.5
6.3
28
86
5239
FHL
Other measure in this category
+∞
6.3
6
*
FBE20
NOMESCO Finland
Reconstruction of pulmonary artery using tube graft
+∞
6.3
6
*
74642
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium secundum
+∞
6.3
6
*
FBE00
NOMESCO Finland
Expansion of pulmonary artery
+∞
6.3
6
*
5233
FHL
Right ventricular bypass surgery (Fontan et al.)
+∞
6.3
6
*
7468B
ICD-9 Finland
Other congenital anomalies of heart, Other specified anomalies of heart[STENOSIS PULMONALIS INFUNDIBULARIS]
+∞
6.3
6
*
Q23.3
ICD-10 Finland
Congenital mitral insufficiency
27.3
6.3
8
*
Q24.8
ICD-10 Finland
Other specified congenital malformations of heart
27.3
6.3
8
*
B01AB05
ATC
enoxaparin; parenteral
2.5
6.1
48
212
I35.0
ICD-10 Finland
Aortic (valve) stenosis
12.9
6.1
10
8
205
Kela drug reimbursment
Chronic hypertension
3.0
6.1
34
121
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
3.1
6.1
32
112

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
133
99
23.11
152.57
7.4
4.7
180.4
207.3
ng/l
0.18
127
87
201
300
17.82
149.63
9.4
5.1
736.6
904.6
ng/l
0.51
195
245
176
560
6.09
55.27
13.1
6.1
1.5
1.1
inr
2.59
32
178
117
317
5.37
42.54
7.9
3.0
3028.9
1254.0
ng/l
0.89
102
184
148
499
4.83
40.83
3.8
3.2
—
—
—
0
0
158
589
4.50
37.57
11.0
7.4
71.5
89.4
%
15.72
158
583
156
616
4.15
33.40
4.0
3.2
—
—
—
0
0
116
423
3.82
26.84
4.5
4.4
1.7
1.9
mg/l
0.16
84
306
185
938
3.48
25.05
4.8
4.3
—
—
—
0
0
44
77
6.51
24.92
24.5
23.2
—
—
—
0
0
82
256
4.02
23.40
2.7
2.1
—
—
—
0
0
87
291
3.79
22.40
4.7
3.0
22.5
22.7
%
0.04
82
266
202
1152
3.25
21.13
5.8
2.6
—
—
—
0
0
170
919
2.93
18.84
11.5
7.7
19.1
22.0
umol/l
0.62
163
863
101
418
3.12
18.09
5.9
4.2
—
—
—
0
0
53
146
4.19
17.67
23.0
15.2
0.5
0.4
mmol/l
0.06
48
120
64
215
3.50
15.97
1.8
1.5
—
—
—
0
0
93
404
2.88
14.91
18.9
11.5
—
—
—
0
0
16
15
11.20
14.76
2.8
7.3
—
—
—
0
0
40
104
4.28
14.30
27.7
14.1
0.6
0.8
%
1.36
40
104
119
598
2.63
14.26
3.4
3.3
3.2
2.7
mg/l
0.73
109
521
16
16
10.50
14.14
2.8
6.9
—
—
—
0
0
39
103
4.20
13.64
27.9
14.3
1.1
1.3
%
1.70
39
103
136
762
2.42
12.58
7.6
9.3
—
—
—
0
0
96
461
2.58
12.36
20.1
14.2
25.3
24.9
mmol/l
0.82
96
461
26
55
5.08
11.89
6.1
18.6
—
—
—
0
0
80
366
2.61
11.26
16.8
9.0
—
—
—
0
0
161
1013
2.25
10.91
9.2
9.8
—
—
—
0
0
95
481
2.42
10.72
4.8
2.9
34.6
19.2
ng/l
0.74
60
233
189
1279
2.26
10.60
14.2
7.2
5.8
6.2
mmol/l
3.43
183
1182
279
2271
3.78
10.38
30.2
12.7
139.3
139.5
mmol/l
1.51
279
2202
190
1296
2.24
10.35
9.5
9.4
0.5
0.7
%
2.70
182
1237
193
1328
2.24
10.24
9.5
9.3
3.0
3.1
%
0.33
184
1265
167
1090
2.18
10.06
20.9
11.4
1.2
1.2
mmol/l
2.37
159
982
85
421
2.41
9.99
17.5
9.2
5.1
5.1
kpa
0.51
85
398
158
1014
2.16
9.88
24.0
12.0
1.2
1.2
mmol/l
3.88
153
959
193
1340
2.21
9.85
9.7
9.4
9.2
8.2
%
5.28
185
1284
198
1393
2.21
9.72
9.4
9.1
27.2
33.9
%
13.00
190
1338
87
442
2.36
9.61
9.1
10.3
1.6
1.0
mmol/l
1.26
75
348
76
369
2.41
9.27
5.8
3.0
—
—
—
0
0
193
1367
2.13
9.00
9.4
9.0
57.9
51.2
%
11.84
185
1315
27
74
3.91
8.94
9.4
10.5
22.1
23.3
mmol/l
1.16
27
63
193
1381
2.09
8.58
9.9
9.1
0.0
0.0
e9/l
0.68
177
1163
197
1421
2.10
8.56
10.4
9.9
0.2
0.2
e9/l
0.59
180
1222
21
49
4.53
8.54
6.3
19.0
70.7
73.3
%
0.29
21
49
192
1381
2.06
8.30
9.9
9.1
0.6
0.6
e9/l
1.38
176
1165
13
9
15.02
8.27
2.4
2.3
—
—
—
0
0
195
1426
2.02
7.85
9.9
9.1
1.7
2.3
e9/l
13.10
181
1237
199
1482
1.99
7.41
10.2
6.2
99.6
102.4
u/l
0.21
194
1399
62
302
2.32
7.39
2.1
1.8
—
—
—
0
0
202
1521
1.98
7.18
11.3
11.5
3.7
3.7
e9/l
0.09
185
1290
289
2528
3.90
7.06
20.5
9.0
—
—
—
0
0
17
40
4.44
6.84
4.9
22.7
12.7
11.7
%
0.54
17
40
164
1171
1.87
6.64
4.3
3.3
89.9
66.8
ug/l
1.18
159
1108
43
187
2.51
6.54
1.5
1.2
—
—
—
0
0
12
23
5.39
6.06
4.2
2.5
—
—
—
0
0
20
59
3.56
5.97
2.2
2.2
—
—
—
0
0
20
59
3.56
5.97
2.2
2.2
—
—
—
0
0
20
59
3.56
5.97
2.2
2.2
—
—
—
0
0
20
59
3.56
5.97
2.2
2.2
—
—
—
0
0
87
527
1.91
5.73
3.1
2.9
54.2
60.5
u/l
0.74
82
491
20
62
3.38
5.55
2.0
2.4
—
—
—
0
0
16
43
3.87
5.44
6.2
7.4
—
—
—
0
0
13
30
4.48
5.35
2.2
2.2
—
—
—
0
0
124
854
1.76
5.32
4.1
4.8
13.5
39.7
e6/l
1.83
89
556
14
35
4.14
5.23
1.9
1.8
—
—
—
0
0
75
447
1.90
5.13
3.2
3.2
558.9
583.2
mosm/kgh2o
0.37
64
376
173
1327
1.70
4.91
12.1
10.9
0.0
0.0
e9/l
0.50
153
1032
12
28
4.42
4.87
1.0
1.0
—
—
—
0
0
12
28
4.42
4.87
1.0
1.2
—
—
—
0
0
116
807
1.71
4.67
1.6
1.6
—
—
—
0
0
10
21
4.89
4.56
6.6
2.8
7.4
6.3
mmol/l
—
10
21
104
709
1.71
4.48
3.9
4.2
20.5
41.1
e6/l
0.92
85
530
11
26
4.35
4.39
6.1
2.5
1.4
1.2
mmol/l
0.41
11
26
34
160
2.27
4.35
3.5
5.8
0.2
0.7
%
—
10
52
12
31
3.99
4.30
1.8
1.5
—
—
—
0
0
31
141
2.33
4.29
3.1
5.5
0.0
0.5
%
—
7
33
29
128
2.40
4.28
2.6
2.0
98.4
102.3
u/ml
—
5
10
32
148
2.30
4.26
3.4
6.1
0.0
0.2
%
—
10
46
17
58
3.05
4.08
2.1
3.6
50.5
66.0
%
1.68
17
58
7
7
10.20
4.03
1.1
2.0
—
—
—
0
0
9
14
6.59
4.01
1.1
1.6
12.8
10.7
umol/l
—
9
14
73
464
1.75
3.98
3.6
3.2
4.8
7.4
e6/l
0.74
65
402
270
2418
2.04
3.85
14.0
9.0
27.5
27.4
u/l
0.01
263
2334
96
664
1.65
3.82
3.9
4.1
0.3
0.3
e6/l
0.16
80
484
96
666
1.65
3.77
3.8
4.1
—
—
—
0
0
10
25
4.10
3.73
2.9
1.6
13218.0
7811.5
e6/l
—
10
17
28
130
2.27
3.71
2.6
2.0
—
—
—
0
0
14
45
3.21
3.70
4.8
4.2
59.4
50.5
%
1.20
14
45
13
40
3.35
3.67
1.3
1.2
—
—
—
0
0
46
262
1.89
3.56
5.1
3.2
9.2
9.3
g/l
0.03
46
253
8
13
6.29
3.52
3.3
2.5
4.1
3.9
mmol/l
—
8
13
8
13
6.29
3.52
3.3
2.5
107.5
105.8
mmol/l
—
8
13
8
13
6.29
3.52
1.3
1.5
—
—
—
0
0
8
13
6.29
3.52
3.3
2.5
—
—
—
0
0
88
607
1.63
3.51
3.1
3.1
2.4
2.4
mmol/l
0.43
83
555
272
2463
1.99
3.44
24.6
11.3
26.8
21.9
mg/l
1.55
229
1734
21
89
2.46
3.40
2.2
2.5
—
—
—
0
0
29
144
2.12
3.28
3.5
6.2
0.0
0.0
%
—
8
39
8
15
5.45
3.21
2.1
1.2
—
—
—
0
0
14
50
2.89
3.13
1.2
1.2
3.9
3.8
u/ml
—
7
24
39
221
1.88
3.08
4.6
5.0
70.8
65.9
e9/l
0.25
31
148
13
45
2.97
3.06
5.0
4.1
4.3
3.2
e9/l
0.78
13
45
73
496
1.62
3.05
6.3
3.5
7.4
7.4
ph
0.21
16
93
275
2522
1.95
3.00
32.9
14.0
39.5
40.1
%
0.86
248
2194
5
7
7.24
2.56
1.8
3.4
23.4
8.3
%
—
5
7
5
7
7.24
2.56
1.8
3.4
—
—
—
0
0
207
1798
1.47
2.53
4.8
3.6
15.6
14.5
pmol/l
6.19
191
1664
6
12
5.08
2.41
1.0
1.2
—
—
—
0
0
13
52
2.57
2.39
2.0
3.6
15.3
25.2
%
2.50
13
52
5
8
6.33
2.38
1.0
1.1
—
—
—
0
0
13
53
2.52
2.31
2.3
2.5
—
—
—
0
0
7
18
3.95
2.26
3.0
1.2
—
—
—
0
0
14
62
2.32
2.11
1.4
1.5
232.7
324.4
ug/g
—
6
34
9
32
2.87
2.01
6.0
5.5
—
—
—
0
0
71
524
1.46
2.01
2.8
2.4
—
—
—
0
0
38
244
1.64
1.99
1.5
1.5
485.5
30876048.3
pmol/l
0.50
33
217
5
11
4.60
1.95
1.8
3.2
0.6
0.1
e9/l
—
5
11
0
50
0.00
1.90
0.0
1.7
—
3.4
—
0
14
12
52
2.36
1.90
1.1
3.0
—
—
—
0
0
13
59
2.26
1.87
2.2
3.9
34.8
16.5
%
1.64
13
59
10
40
2.55
1.85
1.2
2.2
—
—
—
0
0
6
17
3.58
1.84
4.5
4.5
—
—
—
0
0
63
463
1.45
1.82
1.6
1.8
1.3
1.4
mmol/l
0.45
58
411
172
1497
1.34
1.76
4.9
4.3
—
—
—
0
0
11
48
2.34
1.72
1.3
1.3
—
—
—
0
0
5
13
3.89
1.72
1.4
1.8
4.2
5.3
ug/l
—
5
13
10
42
2.43
1.69
3.5
3.3
15.7
17.3
%
—
5
24
8
31
2.62
1.67
3.9
2.6
—
—
—
0
0
6
19
3.20
1.67
2.7
1.6
31.8
33.2
pg
—
6
19
6
19
3.20
1.67
2.3
1.3
454.8
632.8
mu/l
—
6
14
15
273
0.53
1.66
1.9
1.9
—
—
—
0
0
193
1725
1.33
1.56
3.8
3.1
1.2
1.2
mmol/l
0.93
183
1617
8
33
2.46
1.55
1.1
1.2
—
—
—
0
0
16
278
0.55
1.53
2.0
1.9
—
—
—
0
0
69
534
1.38
1.49
7.1
5.2
—
—
—
0
0
16
276
0.56
1.49
1.9
1.9
—
—
—
0
0
9
37
2.48
1.49
5.3
5.8
—
—
—
0
0
228
2095
1.35
1.48
5.4
4.0
2.1
1.9
mu/l
1.97
218
1960
9
38
2.41
1.47
5.4
4.5
4.7
5.0
kpa
—
9
38
9
38
2.41
1.47
5.4
4.5
7.9
9.4
kpa
—
9
38
16
274
0.56
1.46
1.9
1.9
—
—
—
0
0
177
1576
1.29
1.41
4.4
4.0
36.1
37.8
mmol/mol
1.81
168
1492
17
97
1.80
1.38
1.5
1.8
—
—
—
0
0
6
23
2.64
1.37
1.0
1.8
—
—
—
0
0
74
914
0.75
1.36
1.5
1.7
0.8
3.0
u/ml
2.62
19
167
5
17
2.97
1.36
1.2
1.1
—
—
—
0
0
0
37
0.00
1.35
0.0
1.3
—
—
—
0
0
12
61
2.01
1.34
8.5
11.8
—
—
—
0
0
10
192
0.50
1.33
2.5
2.4
—
—
—
0
0
17
278
0.59
1.32
1.2
1.3
—
—
—
0
0
9
43
2.13
1.31
5.4
4.2
7.4
7.4
ph
—
9
38
84
687
1.31
1.26
2.0
1.8
—
—
—
0
0
23
148
1.60
1.24
3.0
2.0
187.2
165.4
u/ml
0.17
16
70
16
258
0.60
1.19
1.8
1.9
—
—
—
0
0
199
1821
1.27
1.17
4.1
3.3
4.2
4.6
mmol/l
5.05
192
1715
12
67
1.82
1.06
1.5
1.5
—
—
—
0
0
9
46
1.99
1.04
1.8
2.7
—
572.1
—
0
7
9
46
1.99
1.04
6.2
4.8
—
—
—
0
0
38
498
0.73
1.03
2.5
3.4
212.7
103.5
ug/g
0.36
33
395
18
115
1.60
1.02
5.3
3.8
—
—
—
0
0
12
70
1.74
0.94
1.3
1.2
—
—
—
0
0
196
1817
1.22
0.90
4.3
3.4
2.6
2.8
mmol/l
1.73
186
1700
14
216
0.63
0.89
2.0
2.0
—
—
—
0
0
8
43
1.88
0.88
1.4
1.1
—
—
—
0
0
194
1801
1.21
0.86
4.0
3.3
1.3
1.4
mmol/l
3.62
184
1687
9
150
0.59
0.81
1.1
1.1
—
—
—
0
0
32
244
1.35
0.79
1.3
1.3
—
—
—
0
0
0
24
0.00
0.79
0.0
2.1
—
3.1
—
0
19
0
26
0.00
0.79
0.0
1.5
—
—
—
0
0
0
27
0.00
0.78
0.0
22.7
—
1528.1
—
0
27
0
27
0.00
0.78
0.0
13.6
—
749.9
—
0
27
50
411
1.26
0.73
1.6
1.6
—
—
—
0
0
39
481
0.78
0.71
5.1
2.9
1.0
1.0
kg/l
—
5
76
12
180
0.65
0.70
1.1
1.2
10.3
6.9
u/ml
—
7
141
5
28
1.80
0.66
1.6
2.8
—
—
—
0
0
17
120
1.44
0.66
1.0
1.1
—
—
—
0
0
7
44
1.60
0.65
1.0
1.0
162.1
162.3
g/l
—
7
44
12
177
0.66
0.65
1.0
1.2
3.2
1.4
u/ml
—
7
131
39
475
0.79
0.64
1.7
1.8
—
—
—
0
0
5
29
1.74
0.64
1.8
4.6
0.2
1.4
%
—
5
22
11
164
0.66
0.63
1.3
1.3
—
—
—
0
0
18
130
1.41
0.63
1.0
1.2
—
—
—
0
0
14
197
0.70
0.61
1.1
1.3
26.5
2.7
u/ml
—
9
130
0
20
0.00
0.60
0.0
1.3
—
19.4
—
0
7
0
20
0.00
0.60
0.0
1.3
—
24.2
—
0
5
0
21
0.00
0.60
0.0
2.7
—
—
—
0
0
0
21
0.00
0.60
0.0
8.5
—
0.6
—
0
21
0
21
0.00
0.60
0.0
5.3
—
—
—
0
0
6
36
1.68
0.57
5.0
4.1
24.8
28.5
umol/l
—
6
36
5
89
0.55
0.57
1.0
1.1
—
—
—
0
0
8
55
1.47
0.56
11.4
6.7
—
—
—
0
0
6
37
1.63
0.56
5.0
3.2
15.3
26.5
mg/l
—
6
26
9
132
0.67
0.53
2.3
2.2
—
—
—
0
0
40
335
1.22
0.52
3.3
3.4
210.6
120.6
mg/l
0.49
24
238
29
234
1.26
0.52
1.4
1.6
—
—
—
0
0
171
1613
1.14
0.50
6.7
4.3
7.9
8.4
mm/h
0.23
165
1495
38
318
1.22
0.50
1.4
1.4
391.1
369.6
titre
—
9
50
33
395
0.82
0.48
1.3
1.2
—
—
—
0
0
19
147
1.31
0.46
3.8
1.7
—
—
—
0
0
10
69
1.46
0.45
4.0
2.4
—
—
—
0
0
54
612
0.86
0.44
1.8
1.8
—
—
—
0
0
5
31
1.62
0.43
2.0
1.5
—
—
—
0
0
58
650
0.87
0.41
2.5
2.2
—
—
—
0
0
0
15
0.00
0.41
0.0
2.1
—
37.3
—
0
15
8
59
1.37
0.41
3.6
3.5
20.6
26.6
u/ml
—
8
54
0
16
0.00
0.41
0.0
6.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
7
103
0.67
0.40
1.0
1.0
2.9
3.3
kpa
—
7
89
7
104
0.67
0.40
1.0
1.0
—
—
—
0
0
7
104
0.67
0.40
1.0
1.0
7.4
7.2
kpa
—
7
90
7
104
0.67
0.40
1.0
1.0
21.1
19.4
mmol/l
—
7
104
5
35
1.44
0.39
2.8
6.0
6.3
6.4
mmol/l
—
5
29
9
66
1.37
0.38
1.3
1.6
—
—
—
0
0
5
36
1.40
0.38
2.0
1.9
—
—
—
0
0
5
36
1.40
0.38
1.8
1.9
—
—
—
0
0
9
69
1.31
0.37
1.2
1.3
—
—
—
0
0
12
157
0.75
0.36
1.3
1.2
—
18.4
—
0
6
39
340
1.17
0.35
4.4
4.1
35.1
14.7
mg/mmol
0.78
24
235
111
1041
1.10
0.33
4.0
3.3
0.0
0.0
estimate
0.00
21
188
6
46
1.31
0.33
1.2
5.0
—
—
—
0
0
182
1751
1.10
0.32
3.4
3.0
5.5
5.6
mmol/l
0.50
173
1614
27
231
1.19
0.31
2.1
2.3
2.4
2.4
mmol/l
0.36
22
197
7
53
1.33
0.31
1.9
7.5
43.6
94.7
g/mol
—
7
46
7
53
1.33
0.31
1.7
1.2
—
—
—
0
0
14
173
0.80
0.29
2.4
2.2
—
5.7
—
0
6
59
540
1.11
0.28
3.8
3.3
—
—
—
0
0
57
523
1.11
0.26
4.8
3.4
0.0
0.0
estimate
0.50
20
194
65
605
1.09
0.23
3.4
4.2
6.0
8.2
mmol/l
3.48
59
550
71
757
0.92
0.22
2.0
2.1
—
—
—
0
0
110
1050
1.07
0.22
4.0
3.3
0.0
0.0
estimate
0.00
22
190
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
8.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
1465.0
—
0
10
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
20.1
—
0
13
10
122
0.81
0.19
1.8
1.2
—
—
—
0
0
24
213
1.14
0.19
1.4
1.3
267.9
136.0
iu/ml
—
9
67
109
1045
1.07
0.19
5.4
4.8
0.0
0.0
estimate
0.00
22
200
10
121
0.82
0.18
1.0
1.0
8.0
8.7
mu/l
—
10
107
12
141
0.84
0.16
2.2
2.4
0.3
0.8
ug/l
—
5
78
21
188
1.13
0.15
4.7
3.2
—
—
—
0
0
9
81
1.11
0.15
1.9
1.7
—
—
—
0
0
7
89
0.78
0.14
1.1
1.2
—
—
—
0
0
29
314
0.92
0.13
1.2
1.2
27.4
8.4
u/ml
—
10
113
17
187
0.90
0.10
3.9
2.1
8.0
12.7
iu/l
0.60
17
140
14
125
1.13
0.10
7.9
5.2
—
—
—
0
0
5
46
1.09
0.09
4.4
6.3
3.4
2.1
ug/l
—
5
46
19
206
0.92
0.09
1.5
2.0
—
—
—
0
0
28
263
1.07
0.08
2.7
1.8
—
—
—
0
0
7
66
1.06
0.08
1.1
1.2
—
—
—
0
0
34
323
1.06
0.08
1.4
1.2
16.4
30.6
iu/ml
—
9
90
16
174
0.92
0.08
1.2
1.4
—
—
—
0
0
8
75
1.07
0.07
1.9
1.5
—
—
—
0
0
9
86
1.05
0.07
1.0
1.2
—
—
—
0
0
54
558
0.96
0.07
1.6
1.6
86.8
98.7
pmol/l
1.32
32
284
8
95
0.84
0.06
1.4
1.4
—
—
—
0
0
8
95
0.84
0.06
1.4
1.4
—
—
—
0
0
14
129
1.09
0.05
1.4
1.2
—
—
—
0
0
85
863
0.98
0.03
1.8
1.6
1.8
1.8
g/l
0.17
63
460
55
558
0.98
0.01
3.7
2.8
—
—
—
0
0
13
124
1.05
0.00
1.6
1.4
—
—
—
0
0
23
236
0.97
0.00
1.5
1.4
—
—
—
0
0
60
599
1.00
0.00
1.7
1.7
—
—
—
0
0
85
849
1.00
0.00
4.1
3.1
—
—
—
0
0
11
107
1.03
0.00
1.8
1.9
—
—
—
0
0
21
206
1.02
0.00
1.6
2.5
20622.2
3716.0
u/l
—
5
77
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
9
94
0.96
0.00
1.3
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
17.2
—
0
5
0
7
0.00
0.00
0.0
8.0
—
109.4
—
0
7
0
5
0.00
0.00
0.0
15.0
—
—
—
0
0
6
64
0.94
0.00
1.3
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
3.0
—
6.4
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
71.9
—
0
6
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
4.0
—
47.0
—
0
5
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
4.9
—
—
—
0
0
0
9
0.00
0.00
0.0
1.8
—
133.3
—
0
9
9
94
0.96
0.00
1.3
1.1
—
—
—
0
0
9
98
0.92
0.00
1.3
1.5
—
—
—
0
0
8
79
1.01
0.00
1.6
1.8
1.8
0.5
nmol/l
—
8
68
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
13.6
—
—
—
0
0
0
5
0.00
0.00
0.0
3.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint Q17_RVOTO and mortality.

Females

Parameter HR [95% CI] p-value
Q17_RVOTO 3.515 [2.39, 5.18] < 0.001
Birth year 0.989 [0.98, 1.0] 0.018

During the follow-up period (1.1.1998 — 31.12.2019), 64 out of 1741 females with Q17_RVOTO died.

Males

Parameter HR [95% CI] p-value
Q17_RVOTO 3.988 [2.8, 5.67] < 0.001
Birth year 0.991 [0.98, 1.0] 0.067

During the follow-up period (1.1.1998 — 31.12.2019), 78 out of 1456 males with Q17_RVOTO died.

Mortality risk

Mortality risk for people of age

years, who have Q17_RVOTO.

N-year risk Females Males
1 0.277% 1.065%
5 1.604% 5.562%
10 3.891% 12.841%
15 7.539% 22.479%
20 12.735% 35.979%

Relationships between endpoints

↥

Index endpoint: Q17_RVOTO – Right ventricular outflow tract obstruction

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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