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Right ventricular outflow tract obstruction

Endpoint Browser PheWeb

Q17_RVOTO

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — Q220|Q221|Q222|Q223|Q2240|Q2241|Q226|Q228|Q229|Q243|Q255|Q256
  • Hospital discharge: ICD-9 — 7460B|7460C|7460X|7461B|7461A|7468X|7468B|7473A
  • Hospital discharge: excluded ICD-10 — Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875
  • Hospital discharge: excluded ICD-9 — 758|7595|75683
  • Cause of death: ICD-10 — Q220|Q221|Q222|Q223|Q2240|Q2241|Q226|Q228|Q229|Q243|Q255|Q256
  • Cause of death: ICD-9 — 7460B|7460C|7460X|7461B|7461A|7468X|7468B|7473A
  • Cause of death: excluded ICD-10 — Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875
  • Cause of death: excluded ICD-9 — 758|7595|75683

2 out of 7 registries used, show all original rules.

306

4. Check minimum number of events

None

306

5. Include endpoints

None

306

6. Filter based on genotype QC (FinnGen only)

277

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF7

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4198 2225 1962
Only index persons 2655 1420 1235
Unadjusted period prevalence (%)
Whole population 0.06 0.06 0.05
Only index persons 0.05 0.05 0.05
Median age at first event (years)
Whole population 0.66 0.59 0.58
Only index persons 3.15 3.48 2.76

-FinnGen-

Key figures

All Female Male
Number of individuals 277 150 127
Unadjusted period prevalence (%) 0.06 0.05 0.06
Median age at first event (years) 6.09 8.78 2.91

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
305
Matched controls
3050
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q22.1
ICD-10 Finland
Congenital pulmonary valve stenosis
+∞
201.0
170
*
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
37.6
174.4
119
51
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
26.5
157.4
126
79
201
Kela drug reimbursment
Chronic cardiac insufficiency
50.6
157.0
95
27
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
20.3
155.2
155
148
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
43.5
132.8
83
26
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
13.8
123.4
194
343
XF404
NOMESCO Finland
Ambulatory ECG
18.5
113.8
105
84
C03DA01
ATC
spironolactone; oral
18.8
110.5
100
77
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
67.7
107.8
60
11
XF400
NOMESCO Finland
ECG with 12 standard connections
11.6
106.3
168
291
C03CA01
ATC
furosemide; systemic
12.8
97.9
119
145
XF402
NOMESCO Finland
ECG with work load test
18.9
97.8
86
62
C01AA05
ATC
digoxin; systemic
47.5
96.6
58
15
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
36.1
93.8
61
21
B01AA03
ATC
warfarin; systemic
16.6
93.4
89
74
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
10.9
76.6
100
131
FM2CE, ,
NOMESCO Finland
12.6
74.9
84
89
TPH07
NOMESCO Finland
Cathetrisation of artery
9.8
71.9
103
151
ZXE20
NOMESCO Finland
More than three and less than five hours
8.9
69.5
110
181
GD1AA
NOMESCO Finland
Thorax X-ray examination
7.2
65.2
199
630
Q21.10
ICD-10 Finland
Persistent ostium secundum
20.9
64.2
51
29
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
7.8
63.7
118
229
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
20.2
59.6
48
28
ZXE30
NOMESCO Finland
More than five and less than seven hours
10.4
54.5
68
82
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
22.4
53.8
41
21
I37.0
ICD-10 Finland
Pulmonary valve stenosis
+∞
53.8
50
*
ZXD10
NOMESCO Finland
Scheduled procedure
5.8
51.2
192
691
61
HP
Catheterization and pressure measurement of the left side of the heart
290.6
49.6
49
*
31
HP
Congenital heart failure surgery
152.4
49.5
51
*
Z2221
NOMESCO Finland
Medical doctor
5.5
49.1
166
544
ZXE10
NOMESCO Finland
More than one and less than three hours
5.5
48.7
173
590
WX408
NOMESCO Finland
General anesthesy, balanced
5.3
47.4
162
533
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
8.4
46.3
69
103
Q25.6
ICD-10 Finland
Stenosis of pulmonary artery
+∞
43.8
41
*
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
249.2
43.1
43
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
9.0
41.8
57
76
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
7.7
41.6
66
105
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
61.4
40.9
47
9
XF600
NOMESCO Finland
Bloodpressure measurement
6.3
40.5
83
172
62
HP
Catheterization and pressure measurement of the right side of the heart
441.4
40.1
39
*
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
65.6
39.5
45
8
Q22.0
ICD-10 Finland
Pulmonary valve atresia
+∞
39.4
37
*
I37.1
ICD-10 Finland
Pulmonary valve insufficiency
389.7
35.7
35
*
TFP20
NOMESCO Finland
Cardiodefibrillation
14.0
35.5
34
27
WX404
NOMESCO Finland
Intravenous generell anesthesy
4.4
34.6
128
429
7460C
ICD-9 Finland
Other congenital anomalies of heart, Anomalies of pulmonary valve[VITIUM VALVULAE PULMONALIS CONGENITA CUM STENOSIS]
+∞
34.0
32
*
Q20.3
ICD-10 Finland
Discordant ventriculoarterial connection
190.6
33.4
34
*
Q20.48
ICD-10 Finland
Single ventricle
190.6
33.4
34
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
11.2
33.4
37
37
WX882
NOMESCO Finland
High dependency care
5.9
33.0
69
144
R4110
NOMESCO Finland
Physiotherapy
4.1
31.9
139
519
Z98.8
ICD-10 Finland
Other specified postsurgical states
67.7
31.8
36
6
XF622
NOMESCO Finland
Measurement of minute volume of heart
78.6
31.6
35
5
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
52.4
31.4
37
8
Q24.3
ICD-10 Finland
Pulmonary infundibular stenosis
+∞
30.7
29
*
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
56.2
30.1
35
7
207
Kela drug reimbursment
Chronic arrhythmias
8.2
29.6
42
58
Q21.30
ICD-10 Finland
Tetralogy of Fallot
89.2
29.4
32
*
WX892
NOMESCO Finland
Monitored bed care
5.9
28.6
58
117
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
47.6
28.4
34
8
ZXD05
NOMESCO Finland
Urgent procedure
3.8
28.2
132
510
I48
ICD-10 Finland
Atrial fibrillation and flutter
7.4
27.6
43
66
Q20.1
ICD-10 Finland
Double outlet right ventricle
+∞
27.5
26
*
Z3231
NOMESCO Finland
Registered nurse
3.5
25.6
154
691
ZXE00
NOMESCO Finland
One hour or less
3.5
25.3
172
830
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
8.8
24.3
32
40
5255
FHL
Deep hypothermia (<20 °) with cardiopulmonary resuscitation
+∞
24.3
23
*
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
21.8
24.1
35
18
TPH04
NOMESCO Finland
Cathetrisation of vein
3.9
24.0
90
295
74663
ICD-8 Finland
Congenital anomalies of heart, Stenosis valvulae pulmonalis
+∞
23.2
22
*
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
43.9
23.1
28
7
Q22.2
ICD-10 Finland
Congenital pulmonary valve insufficiency
+∞
22.1
21
*
C01BD01
ATC
amiodarone; systemic
34.1
21.9
28
9
FJF20
NOMESCO Finland
Replacement of pulmonary valve using homograft
123.9
21.9
23
*
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
123.9
21.9
23
*
WX704
NOMESCO Finland
Intubation
5.8
21.7
43
84
G04BE03
ATC
sildenafil; oral
40.4
21.1
26
7
ZX120
NOMESCO Finland
Intravenous
4.6
20.2
53
132
XFE00
NOMESCO Finland
Epicardial ultrasonography
18.0
20.1
31
19
FBJ10
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery with interposition graft
+∞
20.0
19
*
WX872
NOMESCO Finland
Intensive care
16.1
19.9
32
22
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
7.7
19.9
29
41
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
19.9
19.5
29
16
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.6
19.5
78
264
Q22.41
ICD-10 Finland
Tricuspid atresia
+∞
18.9
18
*
FBE32
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery
41.2
18.8
23
6
Z3226
NOMESCO Finland
Physiotherapist
3.1
18.5
102
420
Q87.14
ICD-10 Finland
Noonan's syndrome
101.0
17.8
19
*
FBE35
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery with insertion of stent
101.0
17.8
19
*
C07AA07
ATC
sotalol; systemic
25.9
17.6
24
10
FBE10
NOMESCO Finland
Expansion or reconstruction of pulmonary artery using patch
67.3
16.9
19
*
Q25.78
ICD-10 Finland
Other congenital malformations of pulmonary artery
95.4
16.7
18
*
I37.2
ICD-10 Finland
Pulmonary valve stenosis with insufficiency
179.4
16.7
17
*
I50.9
ICD-10 Finland
Heart failure, unspecified
6.8
16.6
27
43
C09AA02
ATC
enalapril; systemic
4.8
16.5
40
93
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
19.9
16.3
24
13
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
50.4
16.2
19
*
FDF05
NOMESCO Finland
Percutaneous transluminal occlusion of aorto-pulmonary collaterals
63.5
15.9
18
*
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
12.7
15.9
28
24
FJF10
NOMESCO Finland
Replacement of pulmonary valve using biological prosthesis
+∞
15.8
15
*
FJD20
NOMESCO Finland
Bypass of pulmonary valve with ventriculopulmonary prosthesis or homograft
168.3
15.6
16
*
Q21.32
ICD-10 Finland
Pulmonary atresia with Fallot ventricular septal defect
168.3
15.6
16
*
Q25.0
ICD-10 Finland
Patent ductus arteriosus
14.1
15.5
26
20
602
Kela drug reimbursment
Children's severe malnutrition
5.5
14.9
30
59
74734
ICD-8 Finland
Other congenital anomalies of circulatory system, Stenosis, hypoplasia sive aplasia arteriae pulmonalis
+∞
14.7
14
*
Q20.40
ICD-10 Finland
Double inlet left ventricle
+∞
14.7
14
*
WX402
NOMESCO Finland
General anaesthesia
2.7
14.6
106
497
FJE42
NOMESCO Finland
Percutaneous transluminal expansion of pulmonary valve
157.2
14.6
15
*
FPF20
NOMESCO Finland
Implantation of epicardial pacemaker with atrial and ventricular electrodes
157.2
14.6
15
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.3
14.2
60
208
7AX01, ,
NOMESCO Finland
31.7
14.0
18
6
I44.2
ICD-10 Finland
Atrioventricular block, complete
21.3
14.0
20
10
FFC22
NOMESCO Finland
Percutaneous transluminal closure of ostium secundum type ASD
78.8
13.7
15
*
RS224, ,
NOMESCO Finland
13.7
13.6
23
18
Q22.40
ICD-10 Finland
Congenital tricuspid stenosis
+∞
13.6
13
*
1EA01, ,
NOMESCO Finland
146.2
13.6
14
*
R07.4
ICD-10 Finland
Chest pain, unspecified
2.9
13.3
74
300
Q21.19
ICD-10 Finland
Atrial septal defect NOS
42.1
13.3
16
*
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
42.1
13.3
16
*
ZX199
NOMESCO Finland
Other rote
17.7
13.2
20
12
I47.1
ICD-10 Finland
Supraventricular tachycardia
5.4
13.2
27
54
Q25.41
ICD-10 Finland
Persistent right-sided aortic arch
52.4
13.0
15
*
C07AB07
ATC
bisoprolol; oral
2.7
12.9
88
397
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.5
12.8
117
608
WX002
NOMESCO Finland
Sedation and analgesia
3.2
12.7
56
198
5253
FHL
Cardiac lung machine
+∞
12.6
12
*
7468X
ICD-9 Finland
Other congenital anomalies of heart, Other specified anomalies of heart[MUU SYDÄMEN EPÄMUODOSTUMA]
+∞
12.6
12
*
Q22.3
ICD-10 Finland
Other congenital malformations of pulmonary valve
+∞
12.6
12
*
FM1BD
NOMESCO Finland
Extensive CT of heart
135.3
12.5
13
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.7
12.4
83
370
B01AB05
ATC
enoxaparin; parenteral
3.0
12.3
64
249
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
4.6
12.3
31
74
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
17.3
11.8
18
11
XQ903
NOMESCO Finland
Production of other scan or drawing
31.4
11.8
15
5
Q21.0
ICD-10 Finland
Ventricular septal defect
31.4
11.8
15
5
RD210, ,
NOMESCO Finland
4.2
11.7
33
86
FAE00
NOMESCO Finland
Anastomosis to pulmonary artery from superior vena cava
67.6
11.7
13
*
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.4
11.7
47
157
Q21.3
ICD-10 Finland
Tetralogy of Fallot
+∞
11.5
11
*
EBA15
NOMESCO Finland
Extraction of multiple teeth
5.7
11.5
22
41
FBA96
NOMESCO Finland
Other suture or repair of pulmonary artery
124.5
11.5
12
*
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
124.5
11.5
12
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.7
11.4
72
310
Q23.4
ICD-10 Finland
Hypoplastic left heart syndrome
36.5
11.4
14
*
Z2446
NOMESCO Finland
Social worker
2.9
11.3
62
248
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
45.1
11.0
13
*
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
29.2
10.8
14
5
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
3.3
10.7
43
143
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.5
10.7
40
127
FAE10
NOMESCO Finland
Bidirectional anastomosis between superior vena cava and pulmonary artery
113.8
10.5
11
*
Q24.0
ICD-10 Finland
Dextrocardia
113.8
10.5
11
*
Q22.6
ICD-10 Finland
Hypoplastic right heart syndrome
+∞
10.5
10
*
Q24.9
ICD-10 Finland
Congenital malformation of heart, unspecified
+∞
10.5
10
*
7461A
ICD-9 Finland
Other congenital anomalies of heart, Tricuspid atresia and stenosis, congenital[VITIUM VALVULAE TRICUSPIDALIS CONGENITUM CUM ATRESI]
+∞
10.5
10
*
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
10.1
10.4
20
21
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
4.4
10.4
27
66
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
4.0
10.3
30
80
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.7
10.2
24
54
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.8
10.1
32
91
ZX108
NOMESCO Finland
Inhalation
15.7
9.6
15
10
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
31.1
9.5
12
*
I50.0
ICD-10 Finland
Congestive heart failure
12.9
9.5
16
13
Q24.4
ICD-10 Finland
Congenital subaortic stenosis
103.1
9.5
10
*
Q20.8
ICD-10 Finland
Other congenital malformations of cardiac chambers and connections
103.1
9.5
10
*
FHB50
NOMESCO Finland
Transatrial closure of VSD using patch
22.5
9.4
13
6
7460B
ICD-9 Finland
Other congenital anomalies of heart, Anomalies of pulmonary valve[VITIUM VALVULAE PULMONALIS CONGENITUM CUM ATRESIA]
+∞
9.4
9
*
AEX
HP
Other pulmonary or pulmonary artery valve procedure
+∞
9.4
9
*
FAE30
NOMESCO Finland
Total cavo-pulmonary connection using fenestrated patch
+∞
9.4
9
*
ZXA00
NOMESCO Finland
Right side
2.6
9.4
62
272
127
Kela drug reimbursment
Transplant complication
5.3
9.2
19
38
R00.0
ICD-10 Finland
Tachycardia, unspecified
5.0
9.2
20
42
FDA00
NOMESCO Finland
Aortoplasty and aorto-pulmonary shunt for HLHS
37.9
9.1
11
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.4
9.0
70
331
Z94.1
ICD-10 Finland
Heart transplant status
19.3
9.0
13
7
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
11.2
8.9
16
15
F83
ICD-10 Finland
Mixed specific developmental disorders
4.0
8.8
26
70
I49.5
ICD-10 Finland
Sick sinus syndrome
14.6
8.8
14
10
Q26.1
ICD-10 Finland
Persistent left superior vena cava
51.5
8.7
10
*
Q25.1
ICD-10 Finland
Coarctation of aorta
12.1
8.7
15
13
B34.9
ICD-10 Finland
Viral infection, unspecified
3.4
8.6
32
101
205
Kela drug reimbursment
Chronic hypertension
3.2
8.6
36
123
Q24.8
ICD-10 Finland
Other specified congenital malformations of heart
+∞
8.4
8
*
Q20.5
ICD-10 Finland
Discordant atrioventricular connection
+∞
8.4
8
*
7452A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Tetralogy of Fallot[TETRALOGIA FALLOT]
+∞
8.4
8
*
FK1AC
NOMESCO Finland
Right cardioangiography
+∞
8.4
8
*
74639
ICD-8 Finland
Congenital anomalies of heart, Defectus septi ventriculorum
+∞
8.4
8
*
Q25.5
ICD-10 Finland
Atresia of pulmonary artery
+∞
8.4
8
*
Q21.31
ICD-10 Finland
Tetralogy of Fallot and double outlet right ventricle
+∞
8.4
8
*
R50.9
ICD-10 Finland
Fever, unspecified
2.2
8.2
80
417
FB1AD
NOMESCO Finland
CT examination of arteria pulmonalis
12.2
8.2
14
12
3A077, ,
NOMESCO Finland
34.3
8.1
10
*
FEB10
NOMESCO Finland
Decompression and drainage of pericardium
34.3
8.1
10
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
4.3
7.9
21
52
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
4.3
7.9
21
52
UGC02
NOMESCO Finland
Rigid bronchoscopy
11.2
7.9
14
13
R62.0
ICD-10 Finland
Delayed milestone
3.4
7.8
29
92
XF620
NOMESCO Finland
Examination of circulation with color method
46.2
7.8
9
*
FHE30
NOMESCO Finland
Repair of tetralogy of Fallot with transannular patch
46.2
7.8
9
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.3
7.6
67
333
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
6.3
7.5
19
32
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
82.0
7.4
8
*
7455A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ostium secundum type atrial septal defect
82.0
7.4
8
*
Q23.0
ICD-10 Finland
Congenital stenosis of aortic valve
13.8
7.4
12
9
5239
FHL
Other measure in this category
+∞
7.3
7
*
FBE00
NOMESCO Finland
Expansion of pulmonary artery
+∞
7.3
7
*
5504
FHL
Subclavian pulmonary anastomosis (Blalock)
+∞
7.3
7
*
FBE20
NOMESCO Finland
Reconstruction of pulmonary artery using tube graft
+∞
7.3
7
*
FBJ00
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery
+∞
7.3
7
*
AP3
HP
Catheterization of the right and left side of the heart
+∞
7.3
7
*
7453B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Common ventricle[COMMON VENTRICLE]
+∞
7.3
7
*
Q22.8
ICD-10 Finland
Other congenital malformations of tricuspid valve
+∞
7.3
7
*
FM1CD
NOMESCO Finland
Very extensive CT of heart
+∞
7.3
7
*
AP2
HP
Catheterization of the right side of the heart
+∞
7.3
7
*
7451B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[DOUBLE OUTLET RIGHT VENTRICLE]
+∞
7.3
7
*
5233
FHL
Right ventricular bypass surgery (Fontan et al.)
+∞
7.3
7
*
74642
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium secundum
+∞
7.3
7
*
TFP45
NOMESCO Finland
Ablation treatment of non-typical atrial flutter
+∞
7.3
7
*
WW804
NOMESCO Finland
Transfer from treating institution to higher-Level care, accompanied by doctor
16.2
7.3
11
7
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
4.2
7.2
19
47
Q21.21
ICD-10 Finland
Atrioventricular duct
30.8
7.2
9
*
324, ,
NOMESCO Finland
30.8
7.2
9
*
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
20.6
7.2
10
5
I50.1
ICD-10 Finland
Left ventricular failure
12.4
7.1
12
10
JDB10
NOMESCO Finland
Percutaneous gastrostomy
9.1
7.1
14
16
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
7.0
89
510
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.9
7.0
33
121
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
11.3
6.9
12
11
I47.2
ICD-10 Finland
Ventricular tachycardia
9.6
6.9
13
14
TFJ02
NOMESCO Finland
Muscle biopsy of heart
17.2
6.8
10
6
FJD96
NOMESCO Finland
Other operation on right ventricle outlet for congenital or acquired obstruction
41.0
6.8
8
*
Q21.18
ICD-10 Finland
Other spedified atrial septal defect
41.0
6.8
8
*
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
2.8
6.7
34
129
J96.1
ICD-10 Finland
Chronic respiratory failure
23.1
6.7
9
*
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
3.5
6.7
23
69
WZC30
NOMESCO Finland
Teaching
2.5
6.7
43
185
Z3229
NOMESCO Finland
Other healthcare associate professional
2.6
6.7
42
179
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
3.8
6.6
20
55
C09AA05
ATC
ramipril; oral
2.8
6.6
33
125
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.5
6.6
23
70
K80
ICPC
Cardiac arrhythmia NOS
3.6
6.6
22
65
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.7
6.5
37
150
FPJ04
NOMESCO Finland
Revision of pacemaker generator with atrial and ventricular electrodes
71.3
6.4
7
*
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
71.3
6.4
7
*
I28.8
ICD-10 Finland
Other specified diseases of pulmonary vessels
71.3
6.4
7
*
FFK20
NOMESCO Finland
Atrio-pulmonary anastomosis
71.3
6.4
7
*
Q22.5
ICD-10 Finland
Ebstein anomaly
71.3
6.4
7
*
1CX08, ,
NOMESCO Finland
71.3
6.4
7
*
FBE96
NOMESCO Finland
Other expansion or reconstruction of pulmonary artery
71.3
6.4
7
*
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.9
6.4
30
109
K84
ICPC
Heart disease other
9.6
6.3
12
13
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.1
6.3
27
93
SDA03
NOMESCO Finland
Periodontal treatment
1.9
6.3
115
742
Q23.10
ICD-10 Finland
Congenital insufficiency of aortic valve
18.5
6.3
9
5
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
7.3
6.3
14
20
ZSF00
NOMESCO Finland
Procedure related to previous procedure classified in chapter F
+∞
6.3
6
*
7473A
ICD-9 Finland
Other congenital anomalies of circulatory system, Anomalies of pulmonary artery
+∞
6.3
6
*
74654
ICD-8 Finland
Congenital anomalies of heart, Maleformatio valvulae tricuspidalis (morbus Ebstein incluso)
+∞
6.3
6
*
7468B
ICD-9 Finland
Other congenital anomalies of heart, Other specified anomalies of heart[STENOSIS PULMONALIS INFUNDIBULARIS]
+∞
6.3
6
*
FM1DM
NOMESCO Finland
Heart very extensive MRI examination with 3 Tesla magnet
+∞
6.3
6
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
6.2
64
339
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.8
6.1
19
53
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.4
6.1
22
68
RK260, ,
NOMESCO Finland
12.9
6.1
10
8
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
12.9
6.1
10
8
Q53.1
ICD-10 Finland
Undescended testicle, unilateral
8.9
6.1
12
14
I35.0
ICD-10 Finland
Aortic (valve) stenosis
8.9
6.1
12
14
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
6.3
6.1
15
25
TLC00
NOMESCO Finland
Insertion of intrauterine device
3.2
6.1
24
79

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
133
99
23.05
152.53
7.4
4.7
180.40
207.29
ng/l
0.18
127
87
201
301
17.65
149.13
9.4
5.1
736.58
901.24
ng/l
0.50
195
246
181
637
5.53
49.12
17.9
8.2
1.56
1.18
inr
3.03
36
202
118
318
5.42
43.24
7.8
3.0
2999.50
1254.03
ng/l
0.88
103
184
148
502
4.78
40.42
3.8
3.2
—
—
—
0
0
158
590
4.48
37.42
11.0
7.4
71.52
89.40
%
15.75
158
584
156
618
4.12
33.17
4.0
3.1
—
—
—
0
0
116
424
3.80
26.71
4.5
4.3
1.69
1.92
mg/l
0.16
84
306
44
77
6.51
24.92
24.5
23.2
—
—
—
0
0
185
946
3.43
24.50
4.1
3.1
—
—
—
0
0
82
256
4.01
23.39
2.7
2.1
—
—
—
0
0
87
294
3.74
22.02
4.7
3.0
22.46
22.71
%
0.05
82
269
71
211
4.08
21.56
13.9
11.0
106.10
104.82
mmol/l
1.56
71
211
203
1162
3.23
21.04
5.7
2.6
—
—
—
0
0
171
926
2.93
18.89
11.4
7.7
18.96
21.88
umol/l
0.64
165
871
101
418
3.12
18.08
5.9
4.2
—
—
—
0
0
53
146
4.18
17.66
23.0
15.2
0.52
0.43
mmol/l
0.06
48
120
64
216
3.48
15.84
1.8
1.5
—
—
—
0
0
93
404
2.87
14.90
18.9
11.5
—
—
—
0
0
40
104
4.28
14.29
27.7
14.1
0.64
0.75
%
1.36
40
104
119
600
2.61
14.13
3.4
3.3
3.16
2.68
mg/l
0.73
109
523
39
103
4.19
13.64
27.9
14.3
1.06
1.33
%
1.70
39
103
136
763
2.41
12.51
7.6
9.3
—
—
—
0
0
96
461
2.58
12.35
20.1
14.2
25.28
24.85
mmol/l
0.82
96
461
26
55
5.07
11.89
6.1
18.6
—
—
—
0
0
80
366
2.61
11.26
16.8
9.0
—
—
—
0
0
33
89
4.04
11.19
6.7
14.2
0.72
0.59
%
1.49
33
89
96
485
2.43
10.90
4.8
2.9
34.58
19.10
ng/l
0.75
60
235
195
1336
2.27
10.59
9.5
9.2
2.97
3.10
%
0.28
187
1276
189
1282
2.25
10.47
14.2
7.2
5.84
6.25
mmol/l
3.38
183
1185
191
1302
2.25
10.44
9.5
9.4
0.53
0.66
%
2.78
183
1243
280
2281
3.78
10.37
30.1
12.7
139.27
139.54
mmol/l
1.49
280
2213
168
1094
2.19
10.22
20.8
11.4
1.21
1.23
mmol/l
2.39
160
987
195
1348
2.24
10.19
9.7
9.4
9.20
8.23
%
4.85
187
1292
200
1401
2.24
10.06
9.3
9.1
27.26
33.90
%
12.99
192
1349
85
421
2.41
9.98
17.5
9.2
5.13
5.06
kpa
0.51
85
404
158
1017
2.15
9.75
24.0
12.0
1.21
1.23
mmol/l
4.02
153
965
87
442
2.35
9.61
9.1
10.3
1.29
1.01
mmol/l
0.46
77
349
195
1375
2.16
9.33
9.3
9.0
57.86
51.21
%
11.86
187
1323
76
371
2.40
9.14
5.8
3.0
—
—
—
0
0
16
15
11.18
8.90
2.8
7.3
—
—
—
0
0
194
1386
2.10
8.70
9.8
9.1
0.04
0.04
e9/l
0.75
178
1168
198
1427
2.10
8.65
10.3
9.9
0.19
0.20
e9/l
0.58
181
1228
194
1388
2.09
8.64
9.9
9.1
0.61
0.56
e9/l
1.35
178
1174
21
49
4.53
8.54
6.3
19.0
70.74
73.33
%
0.29
21
49
13
9
15.02
8.27
2.4
2.3
—
—
—
0
0
197
1434
2.06
8.16
9.8
9.0
1.69
2.27
e9/l
13.33
183
1251
63
302
2.37
7.81
2.1
1.8
—
—
—
0
0
183
1311
1.99
7.77
10.8
9.7
—
—
—
0
0
200
1491
1.99
7.42
10.2
6.2
99.71
102.21
u/l
0.19
195
1408
203
1527
1.98
7.26
11.2
11.5
3.73
3.70
e9/l
0.08
186
1296
290
2535
3.93
7.13
20.5
8.9
—
—
—
0
0
17
40
4.44
6.84
4.9
22.6
12.65
11.71
%
0.54
17
40
165
1176
1.88
6.75
4.3
3.3
89.78
66.92
ug/l
1.17
160
1113
43
187
2.51
6.54
1.5
1.2
—
—
—
0
0
20
62
3.38
5.55
1.8
2.2
—
—
—
0
0
16
43
3.87
5.44
6.2
7.4
—
—
—
0
0
124
855
1.76
5.29
4.1
4.8
13.54
39.83
e6/l
1.85
89
557
75
451
1.88
4.98
3.3
3.3
557.06
583.67
mosm/kgh2o
0.42
65
380
173
1330
1.69
4.83
12.1
10.9
0.00
0.00
e9/l
0.50
153
1035
8
7
11.69
4.81
1.3
2.0
—
—
—
0
0
116
808
1.70
4.64
1.6
1.6
—
—
—
0
0
12
23
5.39
4.50
4.2
2.5
—
—
—
0
0
104
710
1.71
4.45
3.9
4.2
20.48
41.03
e6/l
0.92
85
531
34
161
2.25
4.29
3.5
5.8
0.57
0.66
%
0.12
15
67
29
128
2.40
4.28
2.6
2.0
98.40
102.30
u/ml
—
5
10
31
142
2.32
4.22
3.1
5.5
0.27
0.57
%
0.61
11
56
32
149
2.28
4.20
3.4
6.1
0.00
0.15
%
1.71
13
54
14
35
4.14
4.15
1.6
1.6
—
—
—
0
0
17
58
3.05
4.08
2.1
3.6
14.88
9.74
%
0.93
17
58
17
58
3.05
4.08
2.1
3.6
50.47
66.03
%
1.68
17
58
9
14
6.59
4.01
1.1
1.6
12.78
10.72
umol/l
—
9
14
73
465
1.75
3.95
3.6
3.2
4.77
7.39
e6/l
0.73
66
409
12
28
4.42
3.86
1.0
1.2
—
—
—
0
0
12
28
4.42
3.86
1.0
1.0
—
—
—
0
0
271
2428
2.04
3.85
14.0
9.0
27.47
27.42
u/l
0.01
264
2344
96
664
1.65
3.82
3.9
4.1
0.33
0.27
e6/l
0.16
80
487
96
666
1.64
3.77
3.8
4.1
—
—
—
0
0
28
130
2.27
3.71
2.6
2.0
—
—
—
0
0
14
45
3.21
3.70
4.8
4.2
59.36
50.51
%
1.20
14
45
10
21
4.89
3.58
6.6
2.8
7.38
6.32
mmol/l
—
10
21
11
26
4.35
3.54
6.1
2.5
1.37
1.20
mmol/l
0.41
11
26
12
31
3.99
3.53
1.8
1.5
—
—
—
0
0
8
13
6.29
3.52
3.3
2.5
—
—
—
0
0
8
13
6.29
3.52
3.3
2.5
4.09
3.85
mmol/l
—
8
13
8
13
6.29
3.52
3.3
2.5
107.50
105.85
mmol/l
—
8
13
8
13
6.29
3.52
1.3
1.5
—
—
—
0
0
46
264
1.87
3.48
5.1
3.2
9.22
9.26
g/l
0.02
46
255
273
2472
1.99
3.45
24.5
11.3
26.67
21.81
mg/l
1.53
230
1741
88
612
1.62
3.38
3.1
3.1
2.37
2.38
mmol/l
0.44
83
561
65
418
1.71
3.37
2.5
3.8
3.55
1.96
e6/l
0.50
40
238
21
90
2.43
3.32
2.2
2.5
—
—
—
0
0
29
145
2.11
3.23
3.5
6.1
0.00
0.04
%
—
8
48
8
15
5.45
3.21
2.1
1.2
—
—
—
0
0
14
50
2.89
3.13
1.2
1.2
3.86
3.79
u/ml
—
7
24
10
25
4.10
3.11
2.9
1.6
13218.00
7811.53
e6/l
—
10
17
13
45
2.97
3.06
5.0
4.1
4.28
3.19
e9/l
0.78
13
45
39
222
1.87
3.03
4.6
5.0
70.83
65.92
e9/l
0.25
31
149
73
498
1.61
3.00
6.3
3.5
7.40
7.40
ph
0.21
16
93
5
7
7.24
2.56
1.8
3.4
23.40
8.29
%
—
5
7
5
7
7.24
2.56
1.8
3.4
—
—
—
0
0
208
1807
1.48
2.54
4.8
3.6
15.56
14.50
pmol/l
6.17
192
1673
6
12
5.08
2.41
1.0
1.2
—
—
—
0
0
13
52
2.57
2.39
2.0
3.6
15.31
25.15
%
2.50
13
52
5
8
6.33
2.38
1.0
1.1
—
—
—
0
0
13
53
2.52
2.31
2.3
2.5
—
—
—
0
0
7
18
3.95
2.26
3.0
1.2
—
—
—
0
0
14
62
2.32
2.11
1.4
1.5
232.67
324.38
ug/g
—
6
34
9
32
2.87
2.01
6.0
5.5
—
—
—
0
0
38
245
1.63
1.96
1.5
1.5
485.48
30734415.69
pmol/l
0.50
33
218
5
11
4.60
1.95
1.8
3.2
0.57
0.13
e9/l
—
5
11
0
50
0.00
1.90
0.0
1.7
—
3.92
—
0
50
12
52
2.36
1.90
1.1
3.0
—
—
—
0
0
13
59
2.26
1.87
2.2
3.9
34.77
16.53
%
1.64
13
59
173
1502
1.35
1.82
4.9
4.2
—
—
—
0
0
63
465
1.45
1.77
1.6
1.8
1.26
1.37
mmol/l
0.46
58
413
71
536
1.42
1.77
2.8
2.4
—
—
—
0
0
6
18
3.38
1.75
4.5
4.3
—
—
—
0
0
11
48
2.34
1.72
1.3
1.3
—
—
—
0
0
5
13
3.89
1.72
1.4
1.8
4.24
5.29
ug/l
—
5
13
10
40
2.55
1.68
1.2
2.3
—
—
—
0
0
8
31
2.62
1.67
3.9
2.6
—
—
—
0
0
6
19
3.20
1.67
2.3
1.3
454.77
632.79
mu/l
—
6
14
15
273
0.53
1.66
1.9
1.9
—
—
—
0
0
10
42
2.43
1.63
3.5
3.3
15.72
17.30
%
—
5
24
6
20
3.04
1.59
2.7
1.5
31.83
32.85
pg
—
6
20
194
1735
1.32
1.56
3.8
3.1
1.16
1.23
mmol/l
1.00
184
1627
8
33
2.46
1.55
1.1
1.2
—
—
—
0
0
16
278
0.55
1.53
2.0
1.9
—
—
—
0
0
16
276
0.56
1.49
1.9
1.9
—
—
—
0
0
9
37
2.48
1.49
5.3
5.8
—
—
—
0
0
229
2105
1.35
1.48
5.5
4.0
2.13
1.89
mu/l
1.89
219
1970
9
38
2.41
1.47
5.4
4.5
7.92
9.38
kpa
—
9
38
9
38
2.41
1.47
5.4
4.5
4.68
4.97
kpa
—
9
38
16
274
0.56
1.46
1.9
1.9
—
—
—
0
0
178
1586
1.29
1.41
4.4
4.0
36.14
37.80
mmol/mol
1.84
169
1502
17
97
1.80
1.38
1.5
1.8
—
—
—
0
0
5
17
2.97
1.36
1.2
1.1
—
—
—
0
0
0
38
0.00
1.35
0.0
1.3
—
—
—
0
0
12
61
2.01
1.34
8.5
11.8
—
—
—
0
0
17
279
0.59
1.33
1.2
1.3
—
—
—
0
0
10
192
0.50
1.33
2.5
2.4
—
—
—
0
0
75
920
0.75
1.31
1.5
1.7
0.75
2.96
u/ml
2.67
20
171
6
24
2.53
1.31
1.0
1.7
—
—
—
0
0
5
118
0.41
1.27
2.4
1.6
—
—
—
0
0
30
205
1.51
1.26
2.1
2.4
27.87
33.42
u/l
0.38
23
173
23
148
1.60
1.24
3.0
2.0
187.19
164.66
u/ml
0.17
16
70
49
371
1.38
1.21
5.7
4.3
9490.78
4131.96
umol/l
0.25
49
343
84
692
1.30
1.19
2.0
1.8
—
—
—
0
0
16
258
0.60
1.19
1.8
1.9
—
—
—
0
0
200
1831
1.27
1.17
4.1
3.4
4.20
4.57
mmol/l
4.91
193
1728
9
46
1.99
1.04
6.2
4.8
—
—
—
0
0
9
46
1.99
1.04
1.8
2.7
396.56
884.09
e6/l
—
9
46
38
498
0.73
1.03
2.4
3.4
210.15
103.42
ug/g
0.35
33
396
12
68
1.80
1.02
1.5
1.5
—
—
—
0
0
18
116
1.59
0.99
5.3
3.8
—
—
—
0
0
12
70
1.74
0.94
1.2
1.2
—
—
—
0
0
11
63
1.77
0.91
2.5
3.6
29.02
35.72
%
0.61
11
63
9
152
0.58
0.91
1.1
1.1
—
—
—
0
0
197
1827
1.22
0.90
4.3
3.5
2.61
2.77
mmol/l
1.76
187
1713
33
247
1.38
0.90
1.3
1.3
—
—
—
0
0
14
216
0.63
0.89
2.0
2.0
—
—
—
0
0
8
43
1.88
0.88
1.4
1.1
—
—
—
0
0
195
1811
1.21
0.86
4.0
3.3
1.31
1.41
mmol/l
3.21
185
1700
18
121
1.52
0.85
1.0
1.1
—
—
—
0
0
19
130
1.49
0.83
1.0
1.2
—
—
—
0
0
0
24
0.00
0.79
0.0
2.1
—
3.07
—
0
19
0
26
0.00
0.79
0.0
1.5
—
—
—
0
0
0
27
0.00
0.78
0.0
22.7
—
1307.56
—
0
27
0
27
0.00
0.78
0.0
13.6
—
749.85
—
0
27
39
484
0.78
0.74
5.1
2.9
1.02
1.02
kg/l
—
5
77
50
412
1.26
0.72
1.6
1.6
—
—
—
0
0
12
180
0.65
0.70
1.1
1.2
10.29
6.93
u/ml
—
7
141
5
28
1.80
0.66
1.6
2.8
—
—
—
0
0
7
44
1.60
0.65
1.0
1.0
162.14
162.30
g/l
—
7
44
12
177
0.66
0.65
1.0
1.2
3.17
1.44
u/ml
—
7
131
39
476
0.79
0.65
1.7
1.8
—
—
—
0
0
14
197
0.70
0.61
1.1
1.3
26.54
3.22
u/ml
—
9
147
0
20
0.00
0.60
0.0
1.3
—
19.43
—
0
7
0
20
0.00
0.60
0.0
1.3
—
24.20
—
0
5
0
21
0.00
0.60
0.0
1.1
—
224.08
—
0
21
0
21
0.00
0.60
0.0
2.7
—
—
—
0
0
0
21
0.00
0.60
0.0
8.5
—
0.58
—
0
21
0
21
0.00
0.60
0.0
5.3
—
—
—
0
0
8
55
1.47
0.56
11.4
6.7
—
—
—
0
0
6
37
1.63
0.56
5.0
4.0
24.83
28.56
umol/l
—
6
37
6
37
1.63
0.56
5.0
3.2
15.30
26.51
mg/l
—
6
26
9
132
0.67
0.53
2.3
2.2
—
—
—
0
0
29
234
1.26
0.52
1.4
1.6
—
—
—
0
0
172
1622
1.14
0.51
6.7
4.3
7.92
8.40
mm/h
0.26
166
1503
40
337
1.22
0.49
3.3
3.4
210.63
118.54
mg/l
0.50
24
243
33
395
0.82
0.48
1.3
1.2
—
—
—
0
0
12
165
0.72
0.48
1.3
1.3
—
—
—
0
0
38
320
1.21
0.47
1.4
1.4
391.11
369.60
titre
—
9
50
54
615
0.85
0.47
1.8
1.8
—
—
—
0
0
10
69
1.46
0.45
4.0
2.4
—
—
—
0
0
19
148
1.30
0.44
3.8
1.7
—
—
—
0
0
5
31
1.62
0.43
2.0
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
2.1
—
37.33
—
0
15
0
15
0.00
0.41
0.0
2.2
—
28.60
—
0
15
8
59
1.37
0.41
3.6
3.5
20.65
26.64
u/ml
—
8
59
0
16
0.00
0.41
0.0
6.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
7
103
0.67
0.40
1.0
1.0
2.89
3.28
kpa
—
7
89
7
104
0.67
0.40
1.0
1.0
7.41
7.18
kpa
—
7
90
7
104
0.67
0.40
1.0
1.0
21.14
19.43
mmol/l
—
7
104
7
104
0.67
0.40
1.0
1.0
—
—
—
0
0
5
35
1.44
0.39
2.8
6.0
6.26
6.42
mmol/l
—
5
29
9
66
1.37
0.38
1.3
1.6
—
—
—
0
0
59
657
0.87
0.38
2.5
2.2
—
—
—
0
0
5
36
1.40
0.38
1.8
1.9
—
—
—
0
0
12
158
0.75
0.38
1.3
1.2
—
18.38
—
0
6
9
69
1.31
0.37
1.2
1.3
—
—
—
0
0
39
342
1.16
0.33
4.2
3.9
35.09
14.59
mg/mmol
0.78
24
237
6
46
1.31
0.33
1.2
5.0
—
—
—
0
0
6
90
0.66
0.33
1.0
1.1
—
—
—
0
0
183
1761
1.10
0.32
3.4
3.0
5.47
5.58
mmol/l
0.56
174
1624
7
53
1.33
0.31
1.9
7.5
43.56
94.68
g/mol
—
7
46
7
53
1.33
0.31
1.7
1.2
—
—
—
0
0
111
1049
1.09
0.28
4.0
3.3
0.00
0.00
estimate
-0.00
23
201
59
542
1.11
0.26
3.8
3.3
—
—
—
0
0
27
236
1.16
0.25
2.1
2.2
2.40
2.42
mmol/l
0.37
22
202
57
526
1.10
0.24
4.8
3.4
0.00
0.01
estimate
0.50
20
196
71
759
0.92
0.24
2.0
2.1
—
—
—
0
0
5
38
1.32
0.23
2.0
2.1
—
—
—
0
0
65
607
1.09
0.22
3.4
4.2
6.22
8.17
mmol/l
2.75
60
559
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
136.00
—
0
10
0
10
0.00
0.21
0.0
8.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
1465.00
—
0
10
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
5
43
1.17
0.21
2.4
1.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
20.15
—
0
13
110
1054
1.07
0.19
4.0
3.4
0.00
0.00
estimate
-0.00
22
192
10
122
0.81
0.19
1.8
1.2
—
—
—
0
0
24
213
1.14
0.19
1.4
1.3
267.93
136.04
iu/ml
—
9
67
10
121
0.82
0.18
1.0
1.0
7.99
8.69
mu/l
—
10
107
109
1049
1.06
0.17
5.4
4.8
0.00
0.00
estimate
-0.00
22
202
12
141
0.84
0.16
2.2
2.4
0.31
0.83
ug/l
—
5
78
29
318
0.90
0.16
1.2
1.2
27.38
8.22
u/ml
—
10
115
9
79
1.14
0.15
1.9
1.7
—
—
—
0
0
7
89
0.78
0.14
1.1
1.2
—
—
—
0
0
19
212
0.89
0.14
2.9
2.1
8.89
11.94
nmol/l
0.90
19
194
21
189
1.12
0.14
4.7
3.2
—
—
—
0
0
26
238
1.10
0.13
1.5
1.4
—
—
—
0
0
10
86
1.17
0.11
1.0
1.2
—
—
—
0
0
17
187
0.90
0.10
3.9
2.1
7.95
12.71
iu/l
0.60
17
140
54
564
0.95
0.10
1.6
1.6
86.85
98.71
pmol/l
1.32
32
286
14
125
1.13
0.10
7.9
5.1
—
—
—
0
0
5
46
1.09
0.09
4.4
6.3
3.44
2.08
ug/l
—
5
46
88
906
0.96
0.09
4.0
3.0
5.80
6.01
ph
—
5
93
7
66
1.06
0.08
1.1
1.2
—
—
—
0
0
7
67
1.05
0.08
1.0
1.1
—
3.63
—
0
9
28
264
1.07
0.08
2.8
1.8
—
—
—
0
0
8
74
1.08
0.07
1.9
1.6
—
—
—
0
0
8
95
0.84
0.06
1.4
1.4
—
—
—
0
0
8
95
0.84
0.06
1.4
1.4
—
—
—
0
0
14
129
1.09
0.05
1.4
1.2
—
—
—
0
0
148
1464
1.02
0.04
4.8
3.9
52.41
34.52
u/l
2.39
140
1414
34
328
1.04
0.04
1.4
1.2
16.44
30.59
iu/ml
—
9
90
55
562
0.97
0.03
3.7
2.8
—
—
—
0
0
20
208
0.96
0.02
1.5
2.0
—
—
—
0
0
17
177
0.96
0.01
1.2
1.4
—
—
—
0
0
86
868
0.99
0.01
1.8
1.6
1.84
1.78
g/l
0.15
64
465
11
108
1.02
0.00
1.8
2.0
—
—
—
0
0
13
125
1.04
0.00
1.6
1.4
—
—
—
0
0
21
205
1.03
0.00
1.6
2.5
20622.20
3716.01
u/l
—
5
77
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
4.9
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
8
79
1.01
-0.00
1.6
1.8
1.81
0.50
nmol/l
—
8
68
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
399.20
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
13.6
—
—
—
0
0
60
600
1.00
-0.00
1.7
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
8.0
—
109.43
—
0
7
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
9
98
0.92
-0.00
1.3
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
15.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.0
—
47.00
—
0
5
6
64
0.94
-0.00
1.3
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
17.16
—
0
5
0
5
0.00
-0.00
0.0
3.2
—
—
—
0
0
9
94
0.96
-0.00
1.3
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
6.44
—
0
5
0
6
0.00
-0.00
0.0
1.5
—
70.00
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
9
94
0.96
-0.00
1.3
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
71.95
—
0
6
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint Q17_RVOTO and mortality.

Females

Parameter HR [95% CI] p-value
Q17_RVOTO 3.515 [2.39, 5.18] < 0.001
Birth year 0.989 [0.98, 1.0] 0.018

During the follow-up period (1.1.1998 — 31.12.2019), 64 out of 1741 females with Q17_RVOTO died.

Males

Parameter HR [95% CI] p-value
Q17_RVOTO 3.988 [2.8, 5.67] < 0.001
Birth year 0.991 [0.98, 1.0] 0.067

During the follow-up period (1.1.1998 — 31.12.2019), 78 out of 1456 males with Q17_RVOTO died.

Mortality risk

Mortality risk for people of age

years, who have Q17_RVOTO.

N-year risk Females Males
1 0.277% 1.065%
5 1.604% 5.562%
10 3.891% 12.841%
15 7.539% 22.479%
20 12.735% 35.979%

Relationships between endpoints

↥

Index endpoint: Q17_RVOTO – Right ventricular outflow tract obstruction

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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