Lichen simplex chronicus and prurigo

L12_LICHSIMPANDPRURIGO

neurodermatitis: an itchy skin disease similar to atopic dermatitis. It tends to result in focal patches—one or many—that are due to frequent rubbing or scratching of the same area over time.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L28
  • Cause of death: ICD-10 L28

2 out of 7 registries used, show all original rules.

2355

4. Check minimum number of events

None

2355

5. Include endpoints

2458

6. Filter based on genotype QC (FinnGen only)

2458

Control definitions (FinnGen only)

Control exclude
L12_DERMATITISECZEMA

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L20-L30
Name in latin
Neurodermatitis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 17097 9353 7639
Only index persons 15358 8556 6802
Unadjusted period prevalence (%)
Whole population 0.24 0.27 0.21
Only index persons 0.29 0.31 0.26
Median age at first event (years)
Whole population 56.19 56.86 55.37
Only index persons 55.35 55.98 54.56

-FinnGen-

Key figures

All Female Male
Number of individuals 2458 1439 1019
Unadjusted period prevalence (%) 0.47 0.49 0.45
Median age at first event (years) 56.44 55.45 57.85

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2182
Matched controls
21820
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D09AB01
ATC
zinc bandage without supplements; topical
71.7
323.0
428
74
L30.9
ICD-10 Finland
Dermatitis, unspecified
12.9
323.0
917
1157
D07AC13
ATC
mometasone; topical
8.0
323.0
1291
3353
L28.1
ICD-10 Finland
Prurigo nodularis
3136.3
323.0
768
*
D07AD01
ATC
clobetasol; topical
13.8
323.0
1133
1582
L28.2
ICD-10 Finland
Other prurigo
827.2
323.0
349
5
E0000UV
ATC
NA
7.4
323.0
1490
4924
L28.0
ICD-10 Finland
Lichen simplex chronicus
983.8
323.0
1075
21
D07AC01
ATC
betamethasone; topical
10.1
323.0
1541
4190
L20.0
ICD-10 Finland
Besnier prurigo
+∞
311.0
291
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
10.5
288.1
617
789
E000001
ATC
NA
6.1
258.0
857
2082
D07BC01
ATC
betamethasone and antiseptics; topical
7.3
234.5
640
1171
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
+∞
218.5
206
*
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
6.8
214.9
614
1181
D07AB02
ATC
hydrocortisone butyrate; topical
4.4
201.0
980
3415
TQW80
NOMESCO Finland
Local dermatologic skincare
28.3
200.6
278
112
L30.3
ICD-10 Finland
Infective dermatitis
41.8
197.9
249
67
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
83.8
170.7
191
25
D07AB08
ATC
desonide; topical
6.7
163.4
459
831
D07CC01
ATC
betamethasone and antibiotics; topical
5.3
157.3
549
1297
XQ802
NOMESCO Finland
Epicutan test
32.0
156.2
209
72
E000002
ATC
NA
5.8
145.5
460
958
L29.9
ICD-10 Finland
Pruritus, unspecified
23.8
136.4
198
91
D07BA04
ATC
hydrocortisone and antiseptics; topical
5.9
133.6
412
825
R06AE07
ATC
cetirizine; oral
3.0
129.4
1197
6243
D02AE01
ATC
carbamide; topical
6.5
111.3
313
549
L30.0
ICD-10 Finland
Nummular dermatitis
15.7
110.5
186
129
A46
ICD-10 Finland
Erysipelas
4.0
107.2
504
1538
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
5.9
105.6
323
629
H02AB06
ATC
prednisolone; systemic
2.7
105.0
1229
7059
L28
ICD-10 Finland
Lichen simplex chronicus and prurigo
32.5
95.0
126
41
D02AX
ATC
Other emollients and protectives
10.9
94.1
187
186
R06AX27
ATC
desloratadine; oral
2.8
86.7
728
3321
E000003
ATC
NA
7.6
85.2
209
298
D07XC01
ATC
betamethasone, combinations; topical
3.9
84.5
393
1165
D07AA02
ATC
hydrocortisone; topical
3.8
83.0
399
1215
N05BB01
ATC
hydroxyzine; systemic
5.6
83.0
261
519
J01DB01
ATC
cefalexin; oral
3.0
79.8
1881
14790
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
+∞
76.5
73
*
L20.8
ICD-10 Finland
Other atopic dermatitis
+∞
76.5
73
*
L29.8
ICD-10 Finland
Other pruritus
26.3
73.6
103
41
E000006
ATC
NA
5.0
73.1
255
567
E000007
ATC
NA
5.8
70.9
213
398
XQ800
NOMESCO Finland
Prick test
5.1
70.0
236
505
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.6
66.7
608
2831
L20
ICD-10 Finland
Atopic dermatitis
+∞
64.9
62
*
XQ848
NOMESCO Finland
Dermatological photography
9.4
63.8
136
153
R06AE09
ATC
levocetirizine; oral
3.0
60.7
413
1598
J01FF01
ATC
clindamycin; systemic
2.2
53.5
687
3731
69830
ICD-8 Finland
Pruritus and related conditions, Lichenification and lichen simplex chronicus
+∞
51.2
49
*
D11AH01
ATC
tacrolimus; topical
509.3
50.6
50
*
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
+∞
50.2
48
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
50.0
1003
6525
J01DA01
ATC
[U] cefalexin; systemic
2.0
49.9
1426
10613
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.7
49.3
378
1557
L30.8
ICD-10 Finland
Other specified dermatitis
11.8
48.1
90
79
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.8
47.5
349
1398
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
3.1
45.8
278
983
C03CA01
ATC
furosemide; systemic
2.1
45.0
660
3744
D07AC14
ATC
methylprednisolone aceponate; topical
4.5
44.6
166
390
R06AX22
ATC
ebastine; oral
2.4
44.0
423
1967
L50.3
ICD-10 Finland
Dermatographic urticaria
10.9
43.1
84
80
L40.0
ICD-10 Finland
Psoriasis vulgaris
4.8
42.6
148
324
L23.0
ICD-10 Finland
Allergic contact dermatitis due to metals
219.1
42.0
43
*
6983B
ICD-9 Finland
Pruritus and related conditions, Lichenification and lichen simplex chronicus[NEURODERMATITIS CIRCUMSCRIPTA]
+∞
39.7
38
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
38.7
682
4109
D05BB02
ATC
acitretin; oral
7.0
38.6
98
146
R03AC02
ATC
salbutamol; inhalant
1.8
38.4
1127
8105
L43.9
ICD-10 Finland
Lichen planus, unspecified
7.2
37.7
94
136
S18
ICPC
Laceration/cut
1.8
36.1
929
6353
S97
ICPC
Chronic ulcer skin
3.6
35.5
172
512
S29
ICPC
Skin symptom/complaint other
2.2
35.1
400
1999
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
6.4
34.4
93
151
L04AD01
ATC
ciclosporin; systemic
7.2
34.4
85
122
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.4
34.0
337
1571
N02AX02
ATC
tramadol; systemic, rectal
1.8
33.6
939
6545
L43.0
ICD-10 Finland
Hypertrophic lichen planus
24.0
33.2
47
20
S76
ICPC
Skin infection other
3.6
33.1
157
459
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
32.9
419
2193
H02AB04
ATC
methylprednisolone; systemic
2.2
32.4
361
1779
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
31.1
756
5005
N02BE01
ATC
paracetamol; systemic, rectal
2.0
31.0
1850
16119
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
6.2
30.5
84
140
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.3
30.2
296
1367
S02
ICPC
Pruritus
4.4
30.2
114
272
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
4.0
29.9
125
328
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
29.8
867
6045
L43.8
ICD-10 Finland
Other lichen planus
6.8
29.7
76
115
D05AX52
ATC
calcipotriol, combinations; topical
3.3
28.9
153
487
J01CF05
ATC
flucloxacillin; systemic
4.0
28.8
119
309
R06AX13
ATC
loratadine; oral
2.1
28.3
345
1763
N03AX16
ATC
pregabalin; oral
1.9
28.0
534
3239
J01MA02
ATC
ciprofloxacin; systemic
1.7
27.8
824
5746
WXQ12
NOMESCO Finland
Psoralen - Ultraviolet A therapy with local sensitivisation
33.2
27.8
36
11
H02AB07
ATC
prednisone; oral
2.1
27.6
334
1697
R06.0
ICD-10 Finland
Dyspnoea
1.8
27.6
535
3264
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
27.5
989
7275
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.0
27.4
434
2462
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.0
27.2
111
285
S87
ICPC
Dermatitis/atopic eczema
6.7
27.2
70
107
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
14.2
27.1
46
33
A02BC02
ATC
pantoprazole; systemic
1.6
26.4
1366
11031
UJF32
NOMESCO Finland
Coloscopy
1.8
26.3
570
3598
6918B
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[ECZEMA ATOPICUM]
+∞
26.1
25
*
L23.8
ICD-10 Finland
Allergic contact dermatitis due to other agents
+∞
26.1
25
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
25.7
695
4692
R50.9
ICD-10 Finland
Fever, unspecified
2.1
25.6
310
1573
A10AE04
ATC
insulin glargine; parenteral
2.4
25.6
237
1063
Z49.1
ICD-10 Finland
Extracorporeal dialysis
7.8
25.5
59
77
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.8
25.4
577
3692
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
5.9
25.3
72
126
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
5.5
25.2
76
143
SPAT1263
SPAT
Sampling
1.6
25.1
891
6476
M79.6
ICD-10 Finland
Pain in limb
1.7
24.9
747
5183
B35.3
ICD-10 Finland
Tinea pedis
3.9
24.8
105
279
J04BA02
ATC
dapsone; oral
19.8
24.8
37
19
D07XB05
ATC
dexamethasone, combinations; topical
4.8
24.5
84
182
L13.0
ICD-10 Finland
Dermatitis herpetiformis
20.3
24.3
36
18
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.1
24.3
299
1527
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.5
24.1
194
808
D11AX14
ATC
[U] tacrolimus; topical
+∞
24.0
23
*
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.8
23.7
531
3370
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.9
23.6
147
524
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.6
23.4
183
748
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
4.1
23.4
94
239
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.2
23.4
264
1296
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
23.3
279
1406
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
23.3
253
1222
103
Kela drug reimbursment
Diabetes, insulin-treated
1.7
23.1
575
3764
L04AX01
ATC
azathioprine; systemic
3.3
23.0
119
373
D01AE15
ATC
terbinafine; topical
2.6
22.9
171
681
N06AA12
ATC
doxepin; systemic
2.9
22.9
144
517
B86
ICD-10 Finland
Scabies
6.6
22.9
59
91
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
22.8
383
2205
J01AA02
ATC
doxycycline; systemic
1.6
22.5
1635
14081
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.8
22.3
488
3065
L23.2
ICD-10 Finland
Allergic contact dermatitis due to cosmetics
63.2
21.9
25
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.3
21.7
216
999
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.8
21.7
74
160
WX110
NOMESCO Finland
Local anesthesy
1.6
21.7
1404
11675
A02BC03
ATC
lansoprazole; oral
1.7
21.6
614
4159
N05CF01
ATC
zopiclone; oral
1.6
21.5
664
4599
S21
ICPC
Skin texture symptom/complaint
2.1
21.5
270
1387
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
21.3
433
2654
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
21.3
1177
9411
R60.0
ICD-10 Finland
Localized oedema
2.2
21.2
240
1178
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.4
21.0
180
774
TK800
NOMESCO Finland
Hemodialysis
4.6
20.9
73
162
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.0
20.9
124
426
L23.9
ICD-10 Finland
Allergic contact dermatitis, unspecified cause
21.7
20.8
30
14
L26
ICD-10 Finland
Exfoliative dermatitis
211.9
20.6
21
*
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.0
20.5
306
1680
G47.3
ICD-10 Finland
Sleep apnoea
1.7
20.5
452
2834
N18.8
ICD-10 Finland
Other chronic renal failure
4.3
20.2
76
182
L12.0
ICD-10 Finland
Bullous pemphigoid
14.5
19.9
33
23
L17
ICPC
Foot/toe symptom/complaint
1.7
19.8
509
3339
N06AX21
ATC
duloxetine; oral
2.1
19.8
239
1206
I50.9
ICD-10 Finland
Heart failure, unspecified
2.0
19.7
268
1420
L73.8
ICD-10 Finland
Other specified follicular disorders
9.9
19.6
39
40
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.9
19.6
315
1777
L23.5
ICD-10 Finland
Allergic contact dermatitis due to other chemical products
201.7
19.6
20
*
R03DC03
ATC
montelukast; oral
1.9
19.6
329
1886
J02AC01
ATC
fluconazole; systemic
1.6
19.5
793
5857
N06AB04
ATC
citalopram; systemic
1.7
19.3
446
2833
M54.5
ICD-10 Finland
Low back pain
1.6
19.1
656
4643
D05AX02
ATC
calcipotriol; topical
3.2
19.0
100
318
L98.1
ICD-10 Finland
Factitial dermatitis
55.5
18.9
22
*
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.4
18.9
166
720
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
4.2
18.9
73
180
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
3.4
18.8
91
272
P01AB01
ATC
metronidazole; oral, rectal
1.5
18.8
809
6042
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.5
18.7
821
6155
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.6
18.7
567
3882
A11CC03
ATC
alfacalcidol; systemic
4.3
18.6
70
168
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
2.2
18.6
207
1008
WXQ10
NOMESCO Finland
Psoralen - Ultraviolet A therapy with systemic sensitivisation
191.5
18.6
19
*
L23.1
ICD-10 Finland
Allergic contact dermatitis due to adhesives
191.5
18.6
19
*
E000004
ATC
NA
5.2
18.5
58
115
K02.1
ICD-10 Finland
Caries of dentine
1.5
18.3
1113
8953
SPAT1262
SPAT
Handing over of treatment supplies
1.8
18.2
387
2391
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
6.9
18.2
45
66
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
2.1
18.2
228
1167
137
Kela drug reimbursment
Uraemia requiring dialysis
9.9
18.1
36
37
AA1AD
NOMESCO Finland
CT of head and brain
1.7
17.9
482
3194
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
3.9
17.8
73
190
C03DA01
ATC
spironolactone; oral
2.1
17.8
225
1158
D11AH02
ATC
pimecrolimus; topical
+∞
17.7
17
*
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
17.7
615
4349
J01CE08
ATC
benzathine benzylpenicillin; parenteral
6.6
17.7
45
69
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
7.0
17.6
43
62
R02
ICPC
Shortness of breath/dyspnoea
2.0
17.6
252
1360
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.8
17.6
118
442
SPAT1260
SPAT
Consultation of another employee
1.8
17.6
367
2253
SPAT1310
SPAT
Counselling related to known health issue
1.6
17.6
620
4400
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.0
17.5
239
1265
D07AC03
ATC
desoximetasone; topical
5.2
17.4
54
106
C08CA13
ATC
lercanidipine; oral
1.9
17.4
271
1509
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
17.4
323
1911
L04AA06
ATC
mycophenolic acid; systemic
5.0
17.4
56
115
R53
ICD-10 Finland
Malaise and fatigue
1.7
17.2
401
2546
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
8.9
17.2
36
41
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.8
17.1
326
1944
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
17.1
834
6366
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
17.1
1391
11822
C07AB07
ATC
bisoprolol; oral
1.5
17.1
931
7279
A02BC01
ATC
omeprazole; systemic
1.6
17.0
559
3888
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
17.0
557
3875
E66.8
ICD-10 Finland
Other obesity
2.6
16.9
124
490
N03AX12
ATC
gabapentin; oral
1.8
16.9
333
2008
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
16.7
439
2878
6983A
ICD-9 Finland
Pruritus and related conditions, Lichenification and lichen simplex chronicus[PRURIGO NODULARIS HYDE]
+∞
16.7
16
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
16.5
322
1931
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
16.4
588
4173
J01MA12
ATC
levofloxacin; systemic
1.7
16.3
377
2387
N06AX11
ATC
mirtazapine; oral
1.5
16.2
632
4577
D07AB01
ATC
clobetasone; topical
3.4
16.1
79
239
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.1
16.1
181
885
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.8
16.1
104
381
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.5
16.1
125
509
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.0
16.1
93
317
127
Kela drug reimbursment
Transplant complication
5.4
16.0
48
91
N06AX16
ATC
venlafaxine; oral
1.8
16.0
286
1668
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
16.0
416
2720
B05DA
ATC
Isotonic solutions
10.8
16.0
30
28
Z94.0
ICD-10 Finland
Kidney transplant status
6.9
15.9
39
57
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.9
15.9
260
1470
A12AA04
ATC
calcium carbonate; oral
5.3
15.9
48
92
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
15.8
446
2979
SPAT1255
SPAT
Intravenous administration of medicine
2.3
15.8
150
680
A10AE05
ATC
insulin detemir; parenteral
2.4
15.8
132
559
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
15.7
648
4743
E66.01
ICD-10 Finland
Obesity due to excess calories
2.2
15.7
162
763
D07CB01
ATC
triamcinolone and antibiotics; topical
4.4
15.7
57
133
C08CA01
ATC
amlodipine; oral
1.5
15.7
702
5231
SPAT1301
SPAT
No procedures
1.5
15.7
630
4585
WW200
NOMESCO Finland
Immunization
3.5
15.7
74
218
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
4.8
15.6
52
111
6929B
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[ECZEMA INFECTIOSUM]
+∞
15.6
15
*
EBA00
NOMESCO Finland
Extraction of tooth
1.5
15.6
632
4608
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.2
15.6
168
806
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.3
15.6
151
690
205
Kela drug reimbursment
Chronic hypertension
1.6
15.6
545
3839
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
15.6
1248
10471
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
7.9
15.6
35
45
L50.9
ICD-10 Finland
Urticaria, unspecified
3.1
15.1
82
268
A02BC05
ATC
esomeprazole; systemic
1.5
15.1
820
6352
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.3
15.1
140
628
D64.9
ICD-10 Finland
Anaemia, unspecified
2.0
15.0
208
1105
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
8.2
15.0
33
41
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.2
14.9
163
786
N06AA09
ATC
amitriptyline; systemic
1.9
14.9
221
1207
A10BA02
ATC
metformin; oral
1.5
14.9
544
3865
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
5.1
14.9
46
91
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.2
14.8
164
794
L04AA01
ATC
[U] ciclosporin; systemic
4.9
14.8
48
100
J01FA06
ATC
roxithromycin; oral
1.5
14.8
801
6196
SPAT1153
SPAT
Removal of sutures
1.5
14.8
635
4678
WQ020
NOMESCO Finland
NA
57.1
14.8
17
*
L08.0
ICD-10 Finland
Pyoderma
7.2
14.8
35
49
R06AX18
ATC
acrivastine; oral
3.5
14.8
69
202
I50.0
ICD-10 Finland
Congestive heart failure
2.3
14.7
139
625
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.2
14.7
150
704
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
14.4
940
7530
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.4
14.4
1020
8303
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.1
14.3
174
877
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
14.3
527
3744
M25.5
ICD-10 Finland
Pain in joint
1.5
14.3
555
3993
L28
ICPC
Limited function/disability (L)
1.7
14.2
308
1907
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.0
14.2
190
1000
P01BA02
ATC
hydroxychloroquine; oral
2.0
14.2
179
917
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.2
14.1
153
737
A06AD11
ATC
lactulose; oral
1.8
14.1
276
1655
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
14.1
1072
8827
H04.10
ICD-10 Finland
Dry eye syndrome
1.9
13.9
202
1094
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
7.5
13.9
32
43
WX002
NOMESCO Finland
Sedation and analgesia
1.6
13.9
399
2666
L24.9
ICD-10 Finland
Irritant contact dermatitis, unspecified cause
30.2
13.9
18
6
R03BA05
ATC
fluticasone; inhalant
1.7
13.8
350
2263
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
11.5
13.8
25
22
N05BA04
ATC
oxazepam; oral
1.5
13.8
477
3338
N06AB03
ATC
fluoxetine; oral
1.8
13.8
258
1527
R03BA01
ATC
beclometasone; inhalant
1.8
13.8
276
1666
B05DB
ATC
Hypertonic solutions
10.5
13.7
26
25
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
13.7
772
5995
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.8
13.6
230
1315
69820
ICD-8 Finland
Pruritus and related conditions, Prurigo
+∞
13.6
13
*
T90
ICPC
Diabetes non-insulin dependent
1.6
13.4
447
3097
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
13.4
721
5545
N05AH04
ATC
quetiapine; oral
1.7
13.4
305
1915
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.9
13.4
212
1185
A10BH01
ATC
sitagliptin; oral
1.9
13.3
193
1044
L21.0
ICD-10 Finland
Seborrhoea capitis
8.1
13.3
29
36
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
4.4
13.3
47
108
M04AA01
ATC
allopurinol; systemic
1.8
13.2
245
1444
KMAK
NOMESCO Finland
NA
1.4
13.2
994
8135
WQ021
NOMESCO Finland
NA
40.3
13.2
16
*
Z49.2
ICD-10 Finland
Other dialysis
7.9
13.1
29
37
L03
ICPC
Low back symptom/complaint
1.5
13.0
458
3209
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
13.0
338
2196
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.2
13.0
131
611
R03BA02
ATC
budesonide; inhalant
1.6
12.8
339
2211
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
5.5
12.8
37
68
S06
ICPC
Rash localized
2.3
12.8
116
513
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.5
12.7
102
425
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.2
12.7
133
629
Z49.0
ICD-10 Finland
Preparatory care for dialysis
6.0
12.7
34
57
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
12.7
530
3862
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
12.6
356
2365
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.9
12.6
181
975
D01AC02
ATC
miconazole; topical
2.0
12.4
158
813
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.4
12.4
103
438
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
12.4
403
2773
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.4
12.3
1105
9279
J45
ICD-10 Finland
Asthma
1.9
12.3
187
1028
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
3.2
12.3
64
205
R42
ICD-10 Finland
Dizziness and giddiness
1.5
12.3
406
2804
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
12.3
280
1756
WZC30
NOMESCO Finland
Teaching
1.7
12.3
261
1605
SPAT1254
SPAT
Administration of medicine
1.7
12.2
280
1757
A07EC01
ATC
sulfasalazine; oral, rectal
2.0
12.2
161
841
R11
ICD-10 Finland
Nausea and vomiting
2.0
12.2
152
776
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.6
12.2
310
2005
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.0
12.2
150
764
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
12.1
558
4142
UJF30
NOMESCO Finland
Ileoscopy through colon
1.9
12.1
187
1034
R03BB04
ATC
tiotropium bromide; inhalant
1.9
12.1
196
1104
J01CA04
ATC
amoxicillin; systemic
1.4
12.0
1607
14442
R52.2
ICD-10 Finland
Other chronic pain
2.9
12.0
74
264
J01AA07
ATC
tetracycline; systemic
1.7
12.0
282
1781
R51.80
ICD-10 Finland
Headache
1.7
12.0
266
1655
UKC02
NOMESCO Finland
Cystoscopy
1.6
11.9
306
1982
L29.2
ICD-10 Finland
Pruritus vulvae
6.8
11.9
29
43
S99
ICPC
Skin disease other
3.9
11.8
48
126
J46
ICD-10 Finland
Status asthmaticus
3.0
11.7
65
218
M48.0
ICD-10 Finland
Spinal stenosis
1.7
11.7
234
1410
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.0
11.7
154
804
B01AB05
ATC
enoxaparin; parenteral
1.4
11.6
575
4323
F34.1
ICD-10 Finland
Dysthymia
2.8
11.6
76
282
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.7
11.5
233
1408
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.3
11.5
103
455
69299
ICD-8 Finland
Other eczema and dermatitis, Due to other and unspecified cause
+∞
11.5
11
*
6929X
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[DERMATITITIS ARTEFACTA NUD]
+∞
11.5
11
*
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
2.5
11.4
86
346
WZA90
NOMESCO Finland
Other doctors statement
1.5
11.4
430
3057
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
3.3
11.4
57
178
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.3
11.4
101
443
E66.00
ICD-10 Finland
Metabolic syndrome
2.2
11.4
115
539
Z71.8
ICD-10 Finland
Other specified counselling
1.5
11.3
436
3111
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.3
11.3
104
466
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.5
11.2
385
2676
J04AB02
ATC
rifampicin; systemic
5.0
11.2
35
71
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
3.5
11.2
52
153
L23.3
ICD-10 Finland
Allergic contact dermatitis due to drugs in contact with skin
17.1
11.2
17
10
L30
ICD-10 Finland
Other dermatitis
3.8
11.2
46
123
TKC20
NOMESCO Finland
Catheterisation of bladder
2.0
11.2
144
745
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.9
11.1
166
907
K08.3
ICD-10 Finland
Retained dental root
2.0
11.1
142
732
L03.9
ICD-10 Finland
Cellulitis, unspecified
3.4
11.1
52
155
SPAT1229
SPAT
Assessment of need for aid
1.9
11.1
156
838
J01CE02
ATC
phenoxymethylpenicillin; oral
1.4
11.0
1345
11786
N18.0
ICD-10 Finland
End-stage renal disease
5.4
11.0
32
60
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
11.0
713
5628
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.6
11.0
298
1956
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.8
11.0
211
1254
NF1AA
NOMESCO Finland
Hip X-ray examination
1.9
11.0
163
892
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
5.0
10.9
34
69
L29
ICD-10 Finland
Pruritus
5.0
10.9
34
69
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
3.0
10.9
60
201
E66.9
ICD-10 Finland
Obesity, unspecified
2.7
10.9
73
277
A02BA02
ATC
ranitidine; systemic
1.5
10.8
377
2627
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.5
10.8
404
2863
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
10.7
746
5953
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
10.7
333
2258
WX290
NOMESCO Finland
Other blockade of nerve
1.4
10.7
796
6424
N05AX08
ATC
risperidone; systemic
1.9
10.7
149
794
L85.9
ICD-10 Finland
Epidermal thickening, unspecified
28.2
10.7
14
5
L85.3
ICD-10 Finland
Xerosis cutis
5.4
10.7
31
58
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.3
10.7
102
463
N05BA01
ATC
diazepam; systemic, rectal
1.7
10.7
254
1607
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.5
10.7
80
323
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
10.7
304
2019
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
2.6
10.7
79
316
N02AA05
ATC
oxycodone; systemic
1.6
10.7
268
1724
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.0
10.7
134
687
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
10.6
454
3305
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
4.2
10.6
39
94
XCK10
NOMESCO Finland
Photography of fundus of eye
1.8
10.6
196
1151
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.8
10.6
68
251
C09AA02
ATC
enalapril; systemic
1.5
10.6
371
2587
RJ411
NOMESCO Finland
NA
8.0
10.6
23
29
A03
ICPC
Fever
1.6
10.6
268
1728
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.5
10.6
462
3383
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.3
10.5
96
428
M75.9
ICD-10 Finland
Shoulder lesion, unspecified
2.4
10.5
90
389
B03BA03
ATC
hydroxocobalamin; parenteral
2.1
10.5
113
544
E0001A1
ATC
NA
3.7
10.5
44
120
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
10.5
145
773
S01GX01
ATC
cromoglicic acid; ophthalmic
1.5
10.5
340
2333
L24.0
ICD-10 Finland
Irritant contact dermatitis due to detergents
+∞
10.4
10
*
M10.9
ICD-10 Finland
Gout, unspecified
2.1
10.4
120
596
J01FA01
ATC
erythromycin; systemic
1.6
10.4
256
1638
SFA40
NOMESCO Finland
Replacement of krone of tooth
1.5
10.4
401
2856
J45.1
ICD-10 Finland
Nonallergic asthma
1.9
10.4
143
761
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
2.9
10.4
61
213
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.6
10.4
74
291
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.3
10.4
97
437
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.0
10.3
127
646
L16
ICPC
Ankle symptom/complaint
1.8
10.3
186
1085
D01BA02
ATC
terbinafine; oral; topical
1.5
10.3
471
3479
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
10.2
226
1403
C02AC05
ATC
moxonidine; oral
2.3
10.2
91
401
R60.9
ICD-10 Finland
Oedema, unspecified
2.3
10.2
96
433
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
7.5
10.2
23
31
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
10.1
190
1121
C08CA05
ATC
nifedipine; systemic
2.0
10.1
120
603
A01AB09
ATC
miconazole; local oral
1.8
10.1
176
1016
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.0
10.1
136
718
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.8
10.1
161
904
L50.8
ICD-10 Finland
Other urticaria
4.1
10.0
38
95
R05
ICD-10 Finland
Cough
1.5
10.0
353
2466
M13.9
ICD-10 Finland
Arthritis, unspecified
2.0
10.0
135
711
L04AA13
ATC
leflunomide; oral
2.8
10.0
62
223
L50.0
ICD-10 Finland
Allergic urticaria
3.3
9.9
49
153
ZXA05
NOMESCO Finland
Left side
1.4
9.9
475
3535
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
9.8
959
8052
H3603, E103
ICD-10 Finland
NA
4.7
9.8
32
69
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.7
9.8
223
1393
T89
ICPC
Diabetes insulin dependent
2.4
9.8
79
330
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
9.6
9.8
19
20
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
9.6
9.8
19
20
N30.0
ICD-10 Finland
Acute cystitis
1.6
9.7
258
1680
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.3
9.7
90
403
A10AE06
ATC
insulin degludec; parenteral
2.7
9.7
65
245
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
3.1
9.7
52
172
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.7
9.7
63
236
S01
ICPC
Pain/tenderness of skin
2.3
9.7
90
406
A10BK03
ATC
empagliflozin; oral
1.9
9.7
135
723
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.4
9.7
486
3647
395
Kela drug reimbursment
Dupilumab
55.2
9.6
11
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
9.6
366
2594
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.6
9.6
271
1795
V03AE02
ATC
sevelamer; oral
8.4
9.5
20
24
RS222
NOMESCO Finland
NA
5.1
9.5
29
58
D07XB01
ATC
flumetasone, combinations; topical
6.4
9.5
24
38
M79.7
ICD-10 Finland
Fibromyalgia
2.5
9.5
72
293
A41.9
ICD-10 Finland
Sepsis, unspecified
2.5
9.5
71
285
RJ420
NOMESCO Finland
NA
9.1
9.5
19
21
ZXA00
NOMESCO Finland
Right side
1.4
9.5
516
3926
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.0
9.5
125
654
R04.0
ICD-10 Finland
Epistaxis
1.9
9.5
135
727
C10AA05
ATC
atorvastatin; oral
1.4
9.5
717
5777
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.9
9.5
131
698
69282
ICD-8 Finland
Other eczema and dermatitis, E microbis
+∞
9.4
9
*
6918C
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[DIATHESIS (CONSTITUTIO) ATOPICA]
+∞
9.4
9
*
QXA70
NOMESCO Finland
Guidance related to rash and skin care
+∞
9.4
9
*
SPAT1216
SPAT
Assessment of functional ability
1.6
9.3
280
1881
SPAT1211
SPAT
Application of soft bandage
1.8
9.3
167
974
RD210
NOMESCO Finland
NA
3.4
9.3
43
128
V03AE03
ATC
lanthanum carbonate; oral
10.7
9.3
17
16
M03BX02
ATC
tizanidine; oral
1.3
9.3
1196
10434
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.6
9.2
256
1688
N05AA02
ATC
levomepromazine; systemic
2.3
9.2
82
363
R74
ICPC
Upper respiratory infection acute
1.4
9.2
480
3621
RS220
NOMESCO Finland
NA
4.4
9.2
32
74
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
9.2
293
1995
A28
ICPC
Limited function/disability NOS
1.6
9.2
261
1733
V03AE01
ATC
polystyrene sulfonate; oral
4.5
9.1
31
70
H03AA01
ATC
levothyroxine sodium; systemic
1.4
9.1
436
3234
I83.2
ICD-10 Finland
Varicose veins of lower extremities with both ulcer and inflammation
6.7
9.1
22
33
L08
ICPC
Shoulder symptom/complaint
1.5
9.1
346
2451
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.3
9.1
78
340
D01AC03
ATC
econazole; topical
2.0
9.1
114
588
RS221
NOMESCO Finland
NA
3.9
9.0
35
90
QCA99
NOMESCO Finland
Other local destruction of skin of upper limb
10.1
9.0
17
17
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
9.0
419
3091
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.6
9.0
250
1647
S06.0
ICD-10 Finland
Concussion
1.7
9.0
188
1150
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
4.1
9.0
33
81
L30.1
ICD-10 Finland
Dyshidrosis [pompholyx]
18.7
8.9
13
7
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.0
8.9
111
571
ACC51
NOMESCO Finland
Release of median nerve
1.8
8.9
142
799
J45.8
ICD-10 Finland
Mixed asthma
2.6
8.9
64
254
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
8.0
8.8
19
24
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.0
8.8
118
620
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.5
8.8
68
281
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.3
8.8
79
351
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
1.9
8.8
124
666
-1
NOMESCO Finland
NA
1.4
8.8
599
4731
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.9
8.8
130
713
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
5.4
8.7
25
47
H02AB09
ATC
hydrocortisone; systemic
2.9
8.7
52
185
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.8
8.7
148
849
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.3
8.7
81
367
R03AK08
ATC
formoterol and beclometasone; inhalant
2.4
8.7
73
315
SPAT1312
SPAT
General health counselling
1.4
8.7
571
4482
N06AB06
ATC
sertraline; oral
1.7
8.7
185
1139
M01AE02
ATC
naproxen; oral, rectal
1.3
8.6
1071
9252
S19
ICPC
Skin injury other
2.3
8.6
75
329
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
5.3
8.6
25
48
L30.4
ICD-10 Finland
Erythema intertrigo
5.3
8.6
25
48
I83.9
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
1.7
8.6
197
1233
L84
ICD-10 Finland
Corns and callosities
2.4
8.6
69
291
J01MA14
ATC
moxifloxacin; systemic
1.7
8.6
166
993
C09CA01
ATC
losartan; oral
1.4
8.6
445
3351
L15
ICPC
Knee symptom/complaint
1.4
8.6
377
2752
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.6
8.6
214
1374
B03XA02
ATC
darbepoetin alfa; parenteral
3.3
8.6
41
126
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.6
8.5
247
1644
TGC00
NOMESCO Finland
Bronchial lavation
2.8
8.5
54
198
QDA99
NOMESCO Finland
Other local destruction of skin of lower limb
9.0
8.5
17
19
K59.09
ICD-10 Finland
Constipation, unspecified
2.0
8.5
108
560
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
2.5
8.5
62
248
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.7
8.5
170
1024
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.9
8.5
122
662
R06AX26
ATC
fexofenadine; oral
1.9
8.5
117
623
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.6
8.4
208
1328
TPH07
NOMESCO Finland
Cathetrisation of artery
1.7
8.4
194
1218
R06.5
ICD-10 Finland
Mouth breathing
1.7
8.4
163
975
K90.0
ICD-10 Finland
Coeliac disease
2.6
8.4
61
242
H3601, E103
ICD-10 Finland
NA
4.4
8.4
29
67
S88
ICPC
Dermatitis contact/allergic
3.2
8.4
41
128
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
2.7
8.4
54
202
SPAT1240
SPAT
Therapeutic discussion
1.7
8.4
174
1063
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
2.8
8.4
53
195
M01AC06
ATC
meloxicam; systemic, rectal
1.3
8.3
686
5573
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.5
8.3
64
263
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
3.9
8.3
32
82
69798
ICD-8 Finland
Lichen, Alius definitus
+∞
8.3
8
*
L71.8
ICD-10 Finland
Other rosacea
4.3
8.3
29
68
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
1.6
8.3
208
1335
R13
ICD-10 Finland
Dysphagia
1.9
8.3
124
683
L40.9
ICD-10 Finland
Psoriasis, unspecified
3.7
8.2
34
93
ZX120
NOMESCO Finland
Intravenous
1.7
8.2
174
1067
K07
ICPC
Swollen ankles/oedema
2.2
8.2
83
392
S02CA02
ATC
flumetasone and antiinfectives; otic
2.0
8.2
107
559
L43
ICD-10 Finland
Lichen planus
4.2
8.2
29
69
A04
ICPC
Weakness/tiredness general
1.6
8.2
221
1448
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.4
8.2
506
3926
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
2.5
8.2
60
242
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
3.1
8.1
42
137
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
8.1
751
6207
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.5
8.1
248
1675
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.2
8.1
79
366
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
8.1
290
2027
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
8.1
808
6751
S08
ICPC
Skin colour change
2.1
8.1
93
462
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
8.1
181
1131
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
3.6
8.0
34
95
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
3.0
8.0
43
144
R4180
NOMESCO Finland
Podiatric therapy
4.3
8.0
28
66
L29.0
ICD-10 Finland
Pruritus ani
5.9
8.0
21
36
R96
ICPC
Asthma
1.7
8.0
157
945
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.2
7.9
76
350
E66
ICD-10 Finland
Obesity
2.1
7.9
81
386
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
6.6
7.9
19
29
D11
ICPC
Diarrhoea
1.6
7.9
179
1122
L01.1
ICD-10 Finland
Impetiginization of other dermatoses
7.8
7.9
17
22
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
7.8
7.9
17
22
WX320
NOMESCO Finland
Spinalanesthesy
1.4
7.9
414
3123
A12BA01
ATC
potassium chloride; oral
2.2
7.8
78
366
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.2
7.8
78
367
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
2.5
7.8
58
236
B81
ICPC
Anaemia vit B12/folate deficiency
2.3
7.8
72
325
R01AD08
ATC
fluticasone; nasal
1.4
7.8
510
3989
Z00.0
ICD-10 Finland
General medical examination
1.5
7.8
315
2257
D01
ICPC
Abdominal pain/cramps general
1.6
7.8
184
1163
RJ410
NOMESCO Finland
NA
7.0
7.8
18
26
T78.4
ICD-10 Finland
Allergy, unspecified
2.2
7.8
77
360
WX204
NOMESCO Finland
Axillary plexus blockaced
2.4
7.7
61
256
K13.29
ICD-10 Finland
Indefinite leukoplakia
3.8
7.7
31
83
D11AH05
ATC
dupilumab; topical
45.1
7.7
9
*
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.7
7.7
146
869
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.0
7.7
99
517
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
4.7
7.6
24
51
R03AK07
ATC
formoterol and budesonide; inhalant
1.4
7.6
337
2457
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
18.4
7.6
11
6
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.4
7.6
342
2503
196
Kela drug reimbursment
Paricalcitol and cinacalcet
8.0
7.6
16
20
N05CD07
ATC
temazepam; oral
1.6
7.6
217
1440
L01.0
ICD-10 Finland
Impetigo [any organism] [any site]
4.0
7.6
28
70
N19
ICD-10 Finland
Unspecified kidney failure
2.4
7.6
59
245
J01XC01
ATC
fusidic acid; systemic
3.6
7.6
32
90
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
3.6
7.6
32
90
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
1.9
7.5
108
585
A01
ICPC
Pain general/multiple sites
1.8
7.5
136
798
R03DC01
ATC
zafirlukast; oral
3.2
7.5
37
117
N06AB05
ATC
paroxetine; oral
1.8
7.5
115
637
A10BB12
ATC
glimepiride; oral
1.8
7.5
130
753
H3600, E103
ICD-10 Finland
NA
4.1
7.5
27
66
TQW99
NOMESCO Finland
Other minor procedure on skin
2.0
7.4
93
479
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
2.7
7.4
48
180
SPAT1097
SPAT
Recording of ECG
1.5
7.4
271
1900
R03AC03
ATC
terbutaline; inhalant
1.5
7.4
250
1723
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
7.4
282
1995
49300
ICD-8 Finland
Asthma, bronchiale
2.8
7.4
47
173
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
2.2
7.4
72
335
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
6.0
7.4
19
32
5613
FHL
Conjunctival occlusion
5.6
7.4
20
36
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.3
7.4
607
4918
EKA10
NOMESCO Finland
Biopsy of cheek
2.8
7.3
44
159
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.0
7.3
86
434
0350X
ICD-9 Finland
Erysipelas[ERYSIPELAS ALIA DEFINITA SEU NUD]
4.7
7.3
23
49
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
8.4
7.3
15
18
134
Kela drug reimbursment
General erythroderma
8.4
7.3
15
18
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
7.3
213
1423
J01MA06
ATC
norfloxacin; oral
1.5
7.3
242
1665
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
1.8
7.3
114
639
WXQ20
NOMESCO Finland
UVA broad spectrum light therapy
+∞
7.3
7
*
69899
ICD-8 Finland
Pruritus and related conditions, Other pruritic conditions
+∞
7.3
7
*
RJ414
NOMESCO Finland
NA
10.9
7.3
13
12
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
10.9
7.3
13
12
L73.9
ICD-10 Finland
Follicular disorder, unspecified
9.4
7.3
14
15
N06AX03
ATC
mianserin; oral
2.0
7.3
90
464
WX892
NOMESCO Finland
Monitored bed care
1.7
7.2
138
823
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.6
7.2
194
1270
Z01.2
ICD-10 Finland
Dental examination
1.3
7.2
729
6077
W00
ICD-10 Finland
Fall on same level involving ice and snow
1.6
7.2
186
1206
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
7.3
7.2
16
22
B01AC04
ATC
clopidogrel; oral
1.5
7.2
257
1794
XKD00
NOMESCO Finland
Uroflowmetry
1.5
7.2
268
1889
J02AC02
ATC
itraconazole; systemic
1.4
7.2
310
2254
SPAT1058
SPAT
PEF monitoring instruction
1.7
7.1
149
911
J01EA01
ATC
trimethoprim; systemic
1.4
7.1
453
3519
SXB00
NOMESCO Finland
Removeal of sutres from oral mucosa
1.8
7.1
114
641
J31.0
ICD-10 Finland
Chronic rhinitis
1.8
7.1
130
762
U07
ICPC
Urine symptom/complaint other
1.9
7.1
104
568
Z00.8
ICD-10 Finland
Other general examinations
1.8
7.1
121
698
H57.1
ICD-10 Finland
Ocular pain
2.3
7.1
59
255
M01AH02
ATC
rofecoxib; oral
1.5
7.0
243
1685
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.2
7.0
70
330
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.5
7.0
53
218
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.4
7.0
378
2857
S91
ICPC
Psoriasis
4.7
7.0
22
47
R4110
NOMESCO Finland
Physiotherapy
1.3
7.0
485
3822
W19
ICD-10 Finland
Unspecified fall
1.6
7.0
167
1061
L25.9
ICD-10 Finland
Unspecified contact dermatitis, unspecified cause
7.0
7.0
16
23
CKC15
NOMESCO Finland
Panretinal photocoagulation
4.1
7.0
25
61
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
2.7
7.0
43
159
SPAT1284
SPAT
Extensive health certificate
2.4
7.0
56
239
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.6
6.9
191
1256
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.2
6.9
67
312
M02AA07
ATC
piroxicam; topical
1.3
6.9
674
5579
N03AE01
ATC
clonazepam; systemic
1.8
6.9
105
583
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
1.8
6.9
105
584
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
6.9
411
3159
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
3.7
6.9
28
77
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
2.1
6.8
71
341
J01AA04
ATC
lymecycline; systemic
1.5
6.8
215
1461
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.4
6.8
299
2177
G04BD12
ATC
mirabegron; oral
1.6
6.8
176
1140
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
2.8
6.8
41
149
L40.8
ICD-10 Finland
Other psoriasis
5.0
6.8
20
40
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.8
6.8
106
595
R05
ICPC
Cough
1.4
6.8
387
2955
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.7
6.8
142
870
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.6
6.8
155
973
SPAT1252
SPAT
Overall medication plan or its review
1.8
6.8
120
701
L29.3
ICD-10 Finland
Anogenital pruritus, unspecified
40.2
6.8
8
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.7
6.8
144
889
QBA99
NOMESCO Finland
Other local destruction of skin of trunk
5.7
6.8
18
32
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
6.7
458
3597
R05FA02
ATC
opium derivatives and expectorants; systemic
1.3
6.7
734
6162
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
1.9
6.7
94
508
K59.0
ICD-10 Finland
Constipation
1.9
6.7
96
523
C01CA24
ATC
epinephrine; parenteral
1.9
6.7
99
542
TK820
NOMESCO Finland
Peritoneal dialysis
7.2
6.7
15
21
UJD02
NOMESCO Finland
Gastroscopy
1.9
6.7
89
469
SPAT1151
SPAT
Treatment of major wounds
3.2
6.7
32
100
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.7
6.7
143
882
A10AA02
ATC
NA
2.2
6.7
65
304
B07.9
ICD-10 Finland
Verruca simplex
2.2
6.7
60
271
L86
ICPC
Back syndrome with radiating pain
1.8
6.7
101
561
H04AA01
ATC
glucagon; nasal, parenteral
2.7
6.6
43
162
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.5
6.6
47
187
B35.1
ICD-10 Finland
Tinea unguium
1.9
6.6
95
518
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.8
6.6
108
614
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
3.1
6.6
34
112
D72.1
ICD-10 Finland
Eosinophilia
7.8
6.6
14
18
C10AC01
ATC
colestyramine; oral
2.5
6.6
50
206
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
5.9
6.6
17
29
M07.3
ICD-10 Finland
Other psoriatic arthropathies
3.5
6.6
28
80
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.1
6.6
69
333
ZXA10
NOMESCO Finland
Bilateral
1.4
6.6
336
2513
ZST00
NOMESCO Finland
Procedure related to previous procedure classified in chapter T
12.3
6.6
11
9
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
3.6
6.6
27
75
R01AD09
ATC
mometasone; nasal
1.3
6.6
802
6831
D69.2
ICD-10 Finland
Other nonthrombocytopenic purpura
8.7
6.5
13
15
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.1
6.5
69
335
E10
ICD-10 Finland
Type 1 diabetes mellitus
2.8
6.5
38
135
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
2.2
6.5
64
302
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
2.0
6.5
82
428
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.0
6.5
81
418
R4120
NOMESCO Finland
Occupational therapy
1.7
6.5
117
686
SBA00
NOMESCO Finland
Microbiological examinations
2.4
6.5
52
221
WXQ26
NOMESCO Finland
UVB broad spectrum light therapy
70.0
6.4
7
*
M79.1
ICD-10 Finland
Myalgia
1.5
6.4
210
1438
A10AA01
ATC
NA
2.4
6.4
52
223
AN1
HP
Coronary angiography
1.5
6.4
198
1340
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
2.4
6.4
49
205
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.8
6.3
96
531
D06
ICPC
Abdominal pain localized other
1.7
6.3
135
834
N03AX09
ATC
lamotrigine; oral
2.0
6.3
74
374
RS211
NOMESCO Finland
NA
8.2
6.3
13
16
TPX10
NOMESCO Finland
Implantation of vascular injection port
2.2
6.3
57
257
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
6.3
691
5795
E66.0
ICD-10 Finland
Obesity due to excess calories
3.4
6.3
28
83
WYA10
NOMESCO Finland
First aid or other corresponding healthcare contact
1.7
6.3
126
763
H05BX01
ATC
cinacalcet; oral
6.0
6.3
16
27
A01AB04
ATC
amphotericin B; local oral
1.9
6.3
88
475
S43.3
ICD-10 Finland
Dislocation of other and unspecified parts of shoulder girdle
9.3
6.3
12
13
ND1AA
NOMESCO Finland
Wrist X-ray examination
1.7
6.3
112
655
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.3
6.3
54
239
C09AA05
ATC
ramipril; oral
1.3
6.3
426
3344
WXQ24
NOMESCO Finland
UVB/UVA light therapy
+∞
6.3
6
*
SPAT1104
SPAT
Monitoring of emergency patient
1.7
6.2
119
712
L88
ICPC
Rheumatoid/seropositive arthritis
2.1
6.2
69
342
WQ066
NOMESCO Finland
NA
26.7
6.2
8
*
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
7.0
6.2
14
20
R1250
NOMESCO Finland
Evaluation of functional capability
2.5
6.2
45
183
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
2.0
6.2
69
343
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
6.2
397
3082
C03AA03
ATC
hydrochlorothiazide; oral
1.6
6.2
163
1064
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
2.4
6.2
48
203
J05AB01
ATC
aciclovir; systemic
1.4
6.1
359
2747
N05BA12
ATC
alprazolam; oral
1.5
6.1
178
1189
L02
ICPC
Back symptom/complaint
1.6
6.1
144
911
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
5.7
6.1
16
28
T78.3
ICD-10 Finland
Angioneurotic oedema
3.2
6.1
30
96
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.1
6.1
66
324
C07AB02
ATC
metoprolol; systemic
1.4
6.1
356
2724
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
2.1
6.1
66
325
EBA30
NOMESCO Finland
Excision of root of tooth
1.8
6.1
100
572
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
1.9
6.1
85
461
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
6.1
457
3638
D06BB04
ATC
podophyllotoxin; topical
2.0
6.1
74
380
D10
ICPC
Vomiting
1.9
6.1
82
436
R05FB02
ATC
cough suppressants and expectorants
1.3
6.1
685
5761
J01CA08
ATC
pivmecillinam; oral
1.3
6.1
706
5963
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.0
6.1
68
340
S10
ICPC
Boil/carbuncle
1.8
6.1
90
497
SPAT1283
SPAT
Restricted health certificate
1.4
6.0
258
1866
H25.1
ICD-10 Finland
Senile nuclear cataract
1.3
6.0
408
3194
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.0
6.0
76
396
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
3.0
6.0
31
103
H61.0
ICD-10 Finland
Perichondritis of external ear
10.0
6.0
11
11
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
2.5
6.0
46
190

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
466
647
8.65
307.65
1.4
1.2
—
—
—
0
0
224
48
51.25
307.65
1.4
1.5
614.2
293.3
titre
—
12
6
394
1029
4.37
137.48
1.5
1.2
846.7
150.9
u/ml
3.50
373
938
1544
9729
2.58
108.99
8.6
5.6
0.0
0.0
e9/l
3.64
1421
8326
1532
9688
2.54
106.17
8.6
5.6
0.6
0.6
e9/l
4.74
1410
8290
1573
10080
2.56
105.78
8.8
5.8
0.2
0.2
e9/l
18.22
1457
8757
1553
9955
2.52
103.34
8.7
5.7
1.8
1.9
e9/l
3.02
1432
8690
539
2173
2.90
93.20
2.2
1.7
—
—
—
0
0
1416
9153
2.29
85.77
9.3
6.2
8.7
8.6
%
0.42
1365
8545
1411
9113
2.29
85.56
9.1
5.9
3.4
2.8
%
13.28
1356
8466
1379
8863
2.27
84.06
9.1
5.9
0.7
0.7
%
1.00
1328
8249
1431
9394
2.25
82.05
9.1
5.9
25.7
28.0
%
13.68
1372
8718
1114
6637
2.24
80.82
8.1
5.7
—
—
—
0
0
1410
9246
2.23
80.44
8.9
5.8
58.5
57.2
%
4.02
1358
8617
1636
11403
2.30
80.24
11.4
8.9
4.3
4.1
e9/l
3.17
1506
9895
785
4141
2.32
75.30
1.4
1.2
2.1
1.5
u/ml
0.65
191
1089
710
3625
2.35
73.17
1.6
1.5
2.7
2.4
g/l
1.59
413
2220
918
5246
2.20
71.78
6.1
4.2
—
—
—
0
0
492
2225
2.51
65.60
1.7
1.4
—
—
—
0
0
1281
8585
2.03
63.03
6.0
4.7
35.0
35.5
g/l
3.11
1205
7973
840
4896
2.09
60.13
2.7
2.2
3.0
3.0
mg/l
0.42
724
4154
547
2742
2.28
57.02
2.4
2.0
—
—
—
0
0
387
1682
2.54
55.43
10.8
7.3
11.2
9.9
mmol/l
2.66
362
1604
1878
14846
2.12
53.82
5.6
4.0
15.2
12.2
mm/h
13.53
1786
13701
511
2552
2.27
53.38
1.5
1.3
542.7
533.7
titre
0.03
118
524
1940
15549
2.18
53.28
9.7
7.3
80.6
78.0
u/l
1.99
1849
14599
318
1314
2.63
50.29
2.0
2.7
—
—
—
0
0
500
2555
2.20
48.96
10.1
5.7
1.1
1.0
mmol/l
4.74
474
2360
954
6146
1.90
48.89
3.2
2.5
56.4
57.4
u/l
0.31
878
5637
359
1606
2.45
47.91
2.2
2.8
67.1
66.4
g/l
1.00
329
1454
1421
10425
1.86
47.87
6.6
6.1
11.0
11.5
umol/l
0.40
1365
9876
562
3063
2.08
46.29
3.7
2.4
12.0
13.3
umol/l
4.38
529
2837
1189
8341
1.82
45.44
3.9
2.7
124.1
131.5
ug/l
0.46
1097
7692
1364
9985
1.82
45.17
10.2
6.6
1.2
1.2
mmol/l
2.85
1158
8399
525
2815
2.10
45.04
3.7
2.4
2.3
2.3
g/l
0.40
491
2613
493
2634
2.09
42.44
3.9
2.5
20.5
23.2
%
4.52
416
2255
1527
11717
1.80
41.68
6.7
4.5
7.1
6.7
mmol/l
6.37
1439
10971
564
3220
1.98
40.13
3.6
3.3
0.8
0.8
mmol/l
2.00
530
3013
906
6022
1.80
39.98
2.5
2.1
202.7
216.1
u/l
0.16
849
5643
1146
8206
1.74
38.68
2.2
2.0
93.3
95.2
pmol/l
0.71
614
4172
191
700
2.87
37.78
1.9
2.8
10.5
10.1
g/l
0.69
160
596
1237
9088
1.73
37.74
9.1
5.8
1.2
1.2
mmol/l
1.65
1135
8185
891
5974
1.77
37.62
3.8
3.1
—
—
—
0
0
311
1448
2.31
37.44
1.2
1.2
—
—
—
0
0
884
5925
1.77
37.29
3.8
3.2
655.0
262.2
mg/l
1.25
606
3659
395
2036
2.12
36.96
2.0
1.6
—
—
—
0
0
354
1763
2.18
36.13
2.3
2.0
349.4
374.2
nmol/l
1.42
325
1599
407
2163
2.06
34.96
2.6
2.7
1.8
1.8
%
0.26
362
1929
1694
13752
1.75
34.40
6.0
4.2
—
—
—
0
0
359
1841
2.11
33.85
5.9
3.7
7.3
7.4
ph
—
5
8
907
6255
1.71
33.74
3.7
3.1
7.1
7.5
mmol/l
1.85
777
5242
906
6247
1.71
33.72
4.7
4.0
17.0
7.6
mg/mmol
2.62
635
3865
1627
13095
1.72
33.72
6.1
4.3
3328.0
1777.0
e6/l
0.32
23
191
869
5946
1.71
33.13
6.8
4.0
7.4
7.4
ph
1.32
185
1128
666
4230
1.79
33.02
6.1
4.3
—
—
—
0
0
597
3673
1.83
32.89
1.9
1.7
1186.7
1181.8
nmol/l
0.04
473
2766
652
4123
1.79
32.77
3.5
2.5
5.3
5.7
e6/l
0.33
577
3603
177
672
2.76
32.70
1.3
1.3
2.1
0.9
u/ml
0.26
11
58
1127
8287
1.66
32.55
2.8
2.2
74.7
77.8
nmol/l
3.41
1037
7420
501
2930
1.89
32.38
2.1
1.7
—
—
—
0
0
144
493
3.04
32.12
1.5
1.7
0.2
0.2
g/l
0.10
134
472
560
3406
1.83
31.91
1.3
1.3
33.1
35.9
iu/ml
0.20
153
1096
774
5194
1.72
31.31
3.4
2.6
4371.6
5293.4
umol/l
0.24
676
4514
1094
8048
1.65
31.07
10.4
9.3
1.2
1.3
inr
0.99
336
2305
145
509
2.96
30.95
1.5
1.6
1.2
1.2
g/l
1.13
136
486
1168
8743
1.64
30.89
14.8
9.2
0.0
0.0
e9/l
0.96
1008
7121
340
1776
2.06
30.33
6.7
3.7
1.6
2.0
mmol/l
1.12
282
1421
831
5730
1.68
30.13
3.5
3.0
2402.2
1377.3
ng/l
2.27
725
4865
341
1788
2.05
30.09
6.0
3.7
5.9
5.8
kpa
0.19
335
1727
699
4618
1.72
29.63
1.7
1.5
20.2
20.9
nmol/l
0.68
616
3925
287
1424
2.15
29.27
2.7
2.7
10.6
10.5
g/l
0.07
258
1294
301
1528
2.11
28.92
5.3
3.7
116.0
89.1
ng/l
3.11
262
1317
1824
15449
1.70
28.16
4.7
4.0
14.8
14.8
pmol/l
0.21
1695
14020
312
1621
2.06
28.14
2.7
2.7
70.4
69.4
e9/l
0.21
242
1215
155
594
2.72
28.09
1.8
2.6
37.9
37.7
g/l
0.20
135
511
848
5981
1.64
27.60
4.3
3.2
86.9
98.1
e6/l
0.08
689
4562
737
5040
1.66
26.97
8.1
6.6
—
—
—
0
0
594
3847
1.72
26.63
3.7
2.7
521.2
547.5
mosm/kgh2o
2.22
521
3263
235
1121
2.21
26.37
2.0
1.8
1.2
1.4
g/l
0.38
210
1021
423
2495
1.84
26.08
1.9
1.6
—
—
—
0
0
957
7025
1.59
26.02
5.0
3.6
104.5
109.2
e6/l
0.05
726
4908
319
1724
1.98
25.65
8.3
7.0
1.4
1.4
mmol/l
0.10
309
1657
385
2217
1.87
25.59
2.5
2.7
6.9
8.0
umol/l
0.60
326
1936
1249
9839
1.55
24.35
4.8
3.6
0.0
0.0
estimate
0.93
241
1734
1235
9712
1.55
24.21
6.3
4.8
0.0
0.0
estimate
0.50
266
1774
1230
9694
1.54
23.67
4.7
3.5
0.0
0.0
estimate
0.00
259
1746
925
6854
1.56
23.50
3.5
3.4
2.3
2.4
mmol/l
1.61
818
5991
997
7513
1.55
23.49
4.1
3.3
—
6.0
—
0
5
754
5340
1.59
23.26
4.2
3.0
—
—
—
0
0
296
1611
1.95
23.22
11.0
8.6
—
—
—
0
0
2214
20158
1.99
23.08
23.5
13.6
24.4
23.7
mg/l
0.44
1925
15841
768
5471
1.59
23.07
4.3
3.0
0.4
0.5
e6/l
0.24
608
4100
507
3262
1.70
22.85
1.3
1.2
12.2
13.0
u/ml
0.08
192
1272
194
913
2.22
22.44
9.4
4.1
23.6
24.1
mmol/l
1.46
172
832
129
505
2.64
22.41
1.1
1.1
8.8
4.4
u/ml
0.36
12
66
294
1618
1.93
22.28
4.7
4.0
0.6
0.9
%
1.32
98
445
272
1463
1.97
22.04
4.4
3.8
0.6
0.6
%
0.05
72
326
170
763
2.32
22.01
1.8
1.9
2.2
1.9
ug/l
0.21
152
676
299
1669
1.90
21.68
2.9
2.8
225.2
195.6
ng/l
0.42
272
1513
556
3716
1.64
21.49
2.7
3.0
2.5
2.5
mmol/l
0.05
483
3280
376
2270
1.77
21.13
2.3
2.2
135.0
137.5
ug/g
0.06
301
1806
279
1537
1.92
21.03
4.8
4.0
0.1
0.1
%
0.57
91
411
2062
18491
1.71
20.95
5.8
4.7
1.9
2.1
mu/l
0.86
1935
16881
55
133
4.21
20.78
1.8
2.0
9.3
6.0
umol/l
0.67
41
87
102
368
2.85
20.73
1.7
1.4
—
—
—
0
0
396
2467
1.72
19.84
9.0
6.9
103.1
104.3
mmol/l
4.26
385
2409
370
2284
1.73
19.11
8.1
7.2
11.4
12.4
kpa
3.01
347
2174
370
2284
1.73
19.11
8.1
7.2
5.1
5.1
kpa
0.00
349
2177
23
25
9.28
19.10
12.1
11.2
4.8
5.5
mmol/l
0.62
23
25
369
2277
1.73
19.08
8.0
7.2
0.8
1.1
mmol/l
0.52
285
1771
977
7575
1.48
18.86
4.6
3.5
43.6
110.5
ng/l
0.57
698
5203
160
749
2.22
18.73
1.1
1.1
2.5
0.9
u/ml
—
5
9
316
1877
1.78
18.64
2.4
2.2
0.2
0.2
g/l
0.39
289
1757
2254
20896
1.95
18.57
25.9
15.8
139.3
139.7
mmol/l
15.08
2217
20356
93
341
2.80
18.37
1.8
1.4
111.1
124.4
u/ml
0.44
31
64
614
4339
1.55
18.36
1.8
1.8
1.3
1.2
mg/l
0.17
484
3325
2258
20958
1.95
18.34
26.2
15.9
4.0
4.0
mmol/l
3.29
2219
20389
25
32
7.88
18.29
1.0
1.2
0.9
0.6
u/ml
0.21
13
15
563
3906
1.57
18.24
4.2
3.6
471.0
411.1
ng/l
0.13
429
3054
333
2033
1.74
17.82
8.2
7.6
94.8
95.5
%
1.26
317
1952
451
3001
1.62
17.34
2.1
2.1
29.8
29.7
s
0.11
441
2920
255
1451
1.85
17.29
4.9
4.1
0.3
0.1
%
0.33
76
354
102
405
2.58
17.26
3.5
2.4
16.1
16.3
%
0.18
56
203
425
2791
1.63
17.23
1.3
1.2
—
—
—
0
0
117
500
2.41
16.94
1.8
2.1
11.8
11.0
mg/l
0.36
108
458
121
532
2.34
16.44
4.1
3.2
1.8
1.5
mg/l
2.16
113
486
73
254
2.93
15.90
1.1
1.1
5.8
4.5
u/ml
0.19
39
120
62
198
3.19
15.65
1.4
1.5
—
21.1
—
0
11
230
1314
1.83
15.35
1.6
1.4
—
—
—
0
0
2053
18752
1.58
15.24
7.5
5.7
41.9
39.8
mmol/mol
14.07
1924
17324
97
400
2.48
15.20
2.9
3.0
30.4
37.7
umol/l
1.59
87
343
102
431
2.43
15.16
6.1
2.9
—
—
—
0
0
174
912
1.98
15.10
5.1
2.5
0.7
0.7
%
0.09
169
879
79
298
2.71
14.83
1.1
1.1
1.8
1.3
u/ml
0.20
36
110
31
62
5.05
14.78
6.2
5.3
—
—
—
0
0
70
248
2.88
14.78
1.1
1.1
0.5
1.2
u/ml
0.62
36
99
624
4606
1.48
14.66
4.3
3.5
—
—
—
0
0
693
5227
1.45
14.53
5.5
3.9
0.0
0.0
estimate
1.08
250
1724
15
13
11.60
14.42
7.0
4.8
—
—
—
0
0
589
4320
1.48
14.23
1.8
1.7
16768127.7
37179918.1
pmol/l
0.54
495
3588
106
469
2.32
14.22
2.0
1.7
12590.2
13993.2
e6/l
0.15
76
352
174
932
1.93
14.18
5.2
2.5
1.4
1.2
%
0.88
174
927
234
1377
1.77
14.14
1.5
1.4
—
—
—
0
0
165
869
1.96
14.13
1.7
1.8
1.7
1.5
g/l
0.84
137
759
34
77
4.46
14.02
1.1
1.1
0.4
1.4
u/ml
0.45
18
22
115
534
2.21
13.77
1.2
1.2
784.0
1273.8
titre
—
5
16
120
567
2.17
13.76
1.9
1.6
—
—
—
0
0
476
3366
1.51
13.69
3.2
2.7
0.8
1.2
e6/l
2.16
267
1902
30
63
4.81
13.54
1.0
1.0
—
—
—
0
0
32
71
4.55
13.53
1.7
1.7
—
—
—
0
0
220
1289
1.78
13.48
5.1
4.6
—
—
—
0
0
190
1066
1.85
13.43
1.4
1.2
—
—
—
0
0
110
507
2.22
13.42
1.3
1.2
26.4
35.7
u/ml
—
7
28
296
1890
1.64
13.23
9.2
7.9
119.8
121.5
g/l
0.70
282
1810
1635
14428
1.40
13.21
4.5
3.7
—
—
—
0
0
111
519
2.19
13.08
1.8
1.4
—
—
—
0
0
33
78
4.27
12.91
32.1
23.4
94.7
122.9
ug/l
1.61
27
63
1512
13196
1.38
12.89
4.0
3.0
55.0
48.6
u/l
2.09
1408
12263
29
62
4.72
12.83
1.1
1.1
—
—
—
0
0
82
339
2.47
12.82
1.9
1.5
—
—
—
0
0
1135
9474
1.37
12.76
4.7
4.0
—
—
—
0
0
97
434
2.29
12.71
6.4
3.6
—
—
—
0
0
83
347
2.44
12.67
6.4
3.0
—
—
—
0
0
50
160
3.17
12.63
1.1
1.5
7.3
6.8
g/l
0.26
36
110
124
615
2.07
12.56
3.0
3.3
—
—
—
0
0
376
2572
1.55
12.53
26.2
24.2
1.4
1.3
inr
0.91
75
348
101
464
2.23
12.43
1.3
1.2
3.5
2.8
u/ml
—
10
49
663
5105
1.41
12.01
5.1
3.8
91.4
90.2
%
0.55
643
4972
101
471
2.19
12.00
1.3
1.2
3.0
7.6
u/ml
0.96
12
83
49
160
3.10
11.98
1.1
1.5
0.5
0.4
g/l
0.42
36
112
49
160
3.10
11.98
1.1
1.5
2.7
3.1
g/l
0.80
35
112
89
395
2.30
11.90
1.5
1.7
—
—
—
0
0
79
335
2.40
11.72
1.5
1.2
272.3
269.2
u/ml
0.03
55
205
96
443
2.21
11.71
7.8
4.3
3.1
2.5
mmol/l
1.16
65
307
14
15
9.38
11.66
1.0
1.0
—
—
—
0
0
49
163
3.05
11.62
1.1
1.5
—
—
—
0
0
203
1215
1.73
11.54
4.9
3.6
5.2
5.2
kpa
0.31
188
1120
87
389
2.28
11.45
5.0
3.4
59.2
56.7
%
1.11
87
389
2114
19711
1.52
11.40
5.5
4.5
6.2
5.9
mmol/l
8.66
1940
17930
75
316
2.42
11.29
1.3
1.4
—
—
—
0
0
564
4266
1.42
11.19
4.9
3.9
1.0
1.0
kg/l
0.37
82
624
60
228
2.67
11.18
1.1
1.0
2.0
1.2
u/ml
0.26
17
52
438
3168
1.47
11.06
3.4
2.9
2.7
2.5
e6/l
0.18
228
1705
199
1200
1.72
11.01
5.0
3.6
7.4
7.4
ph
0.12
42
151
108
535
2.07
11.01
1.2
1.2
91.3
95.2
titre
—
8
44
112
565
2.03
10.87
1.4
1.4
271.1
288.3
ug/g
0.39
71
325
43
138
3.15
10.85
1.2
1.1
—
66.9
—
0
8
179
1053
1.75
10.82
9.6
9.7
24.1
24.3
mmol/l
0.21
169
993
689
5418
1.38
10.81
1.9
1.6
1.5
1.4
mmol/l
3.23
589
4497
64
258
2.52
10.61
1.1
1.1
5.1
2.5
u/ml
1.00
18
120
126
669
1.93
10.58
2.2
2.3
568.5
486.2
ug/l
0.15
119
625
79
351
2.29
10.57
4.0
2.8
—
—
—
0
0
59
229
2.62
10.56
1.8
1.5
56.6
59.3
%
0.19
37
144
67
277
2.46
10.53
1.2
1.6
0.8
0.8
g/l
0.11
49
211
75
328
2.33
10.42
1.3
1.3
61.6
61.8
mmol/l
0.02
62
260
104
519
2.05
10.41
1.3
1.2
—
—
—
0
0
321
2206
1.52
10.38
1.3
1.3
—
—
—
0
0
106
534
2.03
10.34
7.8
4.0
7.4
7.4
ph
0.98
93
437
24
53
4.56
10.24
1.5
1.3
—
—
—
0
0
145
815
1.83
10.22
4.9
4.8
1.7
1.6
%
0.47
133
749
30
79
3.83
10.21
1.2
1.7
12.6
10.0
ug/l
0.26
24
68
264
1744
1.58
10.19
2.5
2.3
6.6
7.5
ug/l
0.22
235
1539
1831
16733
1.37
10.14
27.2
16.8
13.9
13.7
%
9.23
1811
16332
116
608
1.95
10.13
2.9
4.0
42.0
71.9
mg/l
0.73
88
500
116
608
1.95
10.13
3.0
4.0
46.8
66.6
mg/l
0.87
87
502
91
437
2.12
10.09
2.4
2.2
128.5
130.7
g/l
0.34
68
315
71
308
2.34
10.06
1.6
1.4
—
—
—
0
0
180
1084
1.71
10.02
10.5
9.8
—
—
—
0
0
662
5231
1.36
9.94
4.5
3.3
—
—
—
0
0
971
8142
1.32
9.69
2.2
2.1
—
—
—
0
0
92
451
2.08
9.68
3.2
4.2
—
—
—
0
0
50
187
2.71
9.65
1.6
1.3
143443.6
112210.5
e6/l
0.09
38
125
29
78
3.75
9.60
1.1
1.0
0.7
0.5
u/ml
—
9
17
53
206
2.61
9.49
1.1
1.2
—
—
—
0
0
111
591
1.92
9.28
2.7
4.0
1.0
2.6
ratio
—
5
51
140
805
1.78
9.17
5.0
4.9
0.9
0.9
%
0.34
129
741
247
1646
1.56
9.16
6.8
3.6
1.2
1.2
mmol/l
3.97
220
1427
273
1860
1.53
9.16
1.6
1.4
—
—
—
0
0
23
54
4.29
9.12
1.1
1.1
—
—
—
0
0
125
697
1.84
9.06
3.0
3.1
0.3
0.3
g/l
0.07
55
276
13
18
7.26
8.85
1.0
1.0
—
—
—
0
0
37
124
3.01
8.74
1.1
1.2
24.5
35.9
mmol/l
3.27
31
108
53
215
2.50
8.73
1.4
1.2
—
—
—
0
0
2114
19927
1.43
8.66
5.1
4.4
1.4
1.5
mmol/l
9.79
1958
18342
205
1326
1.60
8.65
1.8
1.6
—
—
—
0
0
10
10
10.04
8.64
2.6
3.9
—
—
—
0
0
2127
20080
1.44
8.56
5.3
4.4
4.6
4.7
mmol/l
4.38
1985
18599
96
501
1.95
8.53
4.2
3.1
24.8
24.9
mmol/l
0.06
85
427
238
1600
1.54
8.49
4.1
3.2
—
—
—
0
0
51
206
2.51
8.48
1.2
1.1
—
—
—
0
0
22
53
4.18
8.45
1.4
1.3
—
—
—
0
0
772
6381
1.31
8.21
2.8
2.4
—
—
—
0
0
71
337
2.14
8.17
1.2
1.2
—
—
—
0
0
2255
21569
1.55
8.17
15.4
10.2
26.0
26.3
u/l
0.44
2194
20803
91
475
1.95
8.10
2.6
2.4
189.7
94.0
ug/min
0.53
49
292
268
1872
1.48
7.96
3.2
2.2
31.4
65.4
u/l
0.74
231
1617
2156
20461
1.44
7.89
5.7
4.9
2.7
2.8
mmol/l
3.75
2000
18830
188
1219
1.59
7.86
3.5
3.3
4.4
4.5
pmol/l
0.38
167
1079
67
316
2.15
7.85
1.0
1.1
—
—
—
0
0
47
193
2.46
7.59
1.1
1.0
3.9
2.1
u/ml
0.38
22
61
41
158
2.62
7.53
2.1
2.0
1.2
1.1
e9/l
0.12
24
100
2205
21044
1.46
7.53
21.0
12.9
—
—
—
0
0
81
418
1.97
7.48
3.5
1.9
0.9
0.8
nmol/l
0.86
69
349
188
1236
1.56
7.41
9.1
6.6
24.5
24.6
mmol/l
0.10
169
1141
109
624
1.78
7.31
5.7
5.7
1.3
1.3
mmol/l
0.02
89
533
65
314
2.10
7.19
1.1
1.1
—
—
—
0
0
2040
19259
1.35
7.03
4.7
3.9
1.4
1.3
mmol/l
9.79
1878
17595
42
171
2.48
6.93
1.5
1.4
21.3
32.4
%
1.48
24
104
125
760
1.68
6.79
5.7
4.6
—
—
—
0
0
35
132
2.68
6.74
1.1
1.2
—
—
—
0
0
30
105
2.88
6.63
2.1
2.2
598.7
471.0
e6/l
0.59
24
90
43
182
2.39
6.55
1.2
1.2
—
—
—
0
0
43
182
2.39
6.55
2.3
3.2
63.0
57.1
%
0.83
25
121
190
1290
1.51
6.49
1.2
1.2
111.2
160.1
iu/ml
1.10
72
469
62
307
2.05
6.46
3.1
3.4
1.1
1.5
%
0.70
43
241
42
177
2.40
6.46
1.1
1.0
4.5
3.7
u/ml
0.12
21
59
22
67
3.30
6.13
2.9
1.9
138.3
120.4
umol/l
0.14
11
46
594
4899
1.28
6.13
2.9
2.3
—
—
—
0
0
15
35
4.31
6.02
1.5
1.1
—
—
—
0
0
22
68
3.26
6.00
1.1
1.0
0.3
0.3
u/ml
—
5
7
43
190
2.29
5.97
2.5
2.4
—
—
—
0
0
2316
22471
1.53
5.71
33.8
20.1
91.3
91.1
fl
0.91
2297
22138
2316
22471
1.53
5.71
33.8
20.1
30.3
30.3
pg
0.78
2296
22135
2316
22473
1.53
5.68
34.0
20.2
4.4
4.5
e12/l
7.44
2275
21813
2315
22463
1.53
5.66
34.1
20.2
256.9
250.7
e9/l
4.37
2281
21871
39
170
2.31
5.61
3.3
2.1
9.9
11.1
%
0.85
39
170
2316
22480
1.52
5.59
34.0
20.2
7.0
6.6
e9/l
10.93
2277
21815
2316
22482
1.52
5.57
34.2
20.3
132.8
135.3
g/l
11.76
2297
22145
43
197
2.20
5.51
1.4
1.3
272.4
279.4
mosm/kgh2o
1.18
33
156
28
106
2.66
5.40
1.9
2.6
1796.1
1902.2
ml
0.24
22
91
16
43
3.74
5.36
34.1
6.6
—
—
—
0
0
285
2166
1.36
5.26
1.6
1.6
—
—
—
0
0
44
208
2.14
5.24
3.5
4.1
—
—
—
0
0
21
69
3.06
5.22
1.1
1.1
1806.3
1490.4
miu/ml
0.66
21
69
13
31
4.21
5.09
3.1
3.1
—
12.6
—
0
5
37
165
2.26
5.08
1.1
1.0
0.3
0.1
u/ml
0.79
12
33
130
863
1.53
4.99
5.6
3.6
—
—
—
0
0
94
578
1.65
4.97
1.4
1.2
—
—
—
0
0
100
626
1.62
4.93
1.2
1.1
—
—
—
0
0
227
1685
1.38
4.86
6.1
3.8
—
—
—
0
0
187
1343
1.42
4.85
2.8
3.0
4.3
4.1
e9/l
0.44
142
1048
32
138
2.34
4.76
1.3
1.2
—
—
—
0
0
28
114
2.47
4.71
1.5
2.1
723.0
650.7
e6/l
0.17
12
46
74
434
1.73
4.68
1.7
1.3
14.1
10.5
u/l
1.06
63
354
38
178
2.15
4.66
1.2
1.3
1.5
1.4
nmol/l
0.44
33
158
49
253
1.96
4.64
2.9
2.8
—
—
—
0
0
29
121
2.41
4.64
1.5
1.5
—
—
—
0
0
13
34
3.84
4.53
1.2
1.4
—
—
—
0
0
80
486
1.67
4.47
1.8
1.9
2.7
4.7
iu/l
2.43
31
165
166
1188
1.43
4.41
1.4
1.3
75.0
49.1
au/ml
—
6
52
28
118
2.39
4.40
1.2
1.3
1.3
1.2
nmol/l
0.22
22
94
149
1046
1.45
4.39
2.5
2.4
—
—
—
0
0
50
266
1.90
4.36
1.4
1.4
68.6
45.4
mu/l
0.35
42
240
32
145
2.22
4.28
1.7
1.4
1.3
1.3
promille
0.04
23
110
111
738
1.53
4.27
1.6
2.1
21.1
21.5
s
0.30
103
648
21
78
2.71
4.25
1.1
8.6
49.7
67.0
mg/l
0.88
15
57
180
1318
1.39
4.21
2.6
2.4
28.1
23.7
au/ml
—
6
70
18
62
2.92
4.17
1.5
1.2
37.3
38.0
g/l
—
9
32
678
5890
1.21
4.14
4.3
3.8
—
—
—
0
0
35
167
2.11
4.13
1.5
1.5
—
—
—
0
0
73
1166
0.61
4.12
1.6
1.4
—
—
—
0
0
40
201
2.01
4.12
1.4
2.3
—
—
—
0
0
74
453
1.65
4.05
6.4
6.3
11.8
11.3
mmol/l
0.78
63
395
107
715
1.52
4.04
1.6
1.7
—
—
—
0
0
74
454
1.65
4.01
6.4
6.3
104.1
105.4
mmol/l
1.49
63
396
127
1793
0.69
3.97
1.3
1.4
—
—
—
0
0
40
204
1.98
3.97
1.4
1.4
—
—
—
0
0
110
749
1.49
3.82
1.4
1.4
31.4
32.3
iu/l
0.11
97
638
257
2019
1.30
3.80
5.1
4.2
—
—
—
0
0
17
60
2.85
3.79
1.6
2.1
—
—
—
0
0
28
127
2.22
3.77
2.3
2.2
512.6
490.5
min
0.44
19
94
16
55
2.92
3.73
2.4
2.1
30.9
29.0
%
0.20
16
50
42
223
1.90
3.73
1.5
1.3
42115.5
99416.0
e6/l
0.77
27
127
108
738
1.48
3.70
5.6
3.8
24.7
25.0
mmol/l
0.36
97
690
15
386
0.38
3.61
1.3
1.7
—
—
—
0
0
39
205
1.92
3.58
7.3
5.9
8.1
7.3
mmol/l
0.59
33
169
45
248
1.83
3.58
2.5
2.4
—
—
—
0
0
49
279
1.77
3.51
1.1
1.1
1.5
1.5
g/l
0.07
44
252
33
166
2.00
3.44
1.0
1.1
—
—
—
0
0
22
94
2.35
3.41
5.6
2.8
8.9
9.9
mmol/l
0.51
17
71
17
64
2.67
3.39
1.5
2.2
—
—
—
0
0
18
70
2.58
3.38
2.7
2.6
—
—
—
0
0
40
218
1.85
3.32
1.6
1.5
—
—
—
0
0
40
218
1.85
3.32
1.6
1.5
—
—
—
0
0
40
218
1.85
3.32
1.6
1.5
—
—
—
0
0
40
218
1.85
3.32
1.6
1.5
—
—
—
0
0
638
7207
0.85
3.30
3.3
2.8
—
—
—
0
0
23
102
2.27
3.29
1.6
1.6
—
—
—
0
0
6
7
8.59
3.26
1.0
1.1
—
—
—
0
0
81
537
1.53
3.24
1.9
1.5
302.6
291.4
mu/l
0.10
74
488
87
586
1.50
3.23
6.0
4.0
3.8
3.9
mmol/l
0.37
78
550
175
1335
1.33
3.22
1.3
1.3
—
—
—
0
0
30
150
2.01
3.20
1.2
1.2
193.3
132.0
titre
—
9
30
25
117
2.15
3.16
3.3
3.6
—
—
—
0
0
79
526
1.52
3.11
1.2
1.3
209.1
215.0
miu/ml
0.04
23
241
37
204
1.83
2.99
3.1
3.4
—
—
—
0
0
55
340
1.63
2.98
1.3
1.3
—
—
—
0
0
44
256
1.73
2.98
1.6
1.4
2660.8
1894.5
e6/l
0.35
34
183
26
127
2.06
2.97
2.4
1.9
12.1
14.9
%
0.41
14
49
16
63
2.55
2.95
1.6
2.2
150996.3
2262.9
e6/l
—
8
35
43
250
1.73
2.92
1.3
1.4
387.3
298.5
pmol/l
0.60
32
200
23
108
2.14
2.90
2.2
2.3
—
—
—
0
0
9
22
4.10
2.88
1.0
1.1
—
—
—
0
0
9
22
4.10
2.88
1.0
1.1
—
—
—
0
0
9
22
4.10
2.88
1.0
1.1
—
—
—
0
0
6
9
6.68
2.87
7.3
5.0
446.2
403.8
umol/l
—
6
9
1784
17072
1.16
2.85
29.7
17.8
331.3
332.2
g/l
3.85
1776
16946
18
77
2.35
2.82
1.8
1.6
26.0
29.3
umol/l
0.84
18
72
14
53
2.65
2.79
1.1
1.6
14.9
12.7
g/l
—
8
40
10
31
3.23
2.77
6.8
7.5
—
—
—
0
0
40
232
1.74
2.76
1.4
1.4
—
—
—
0
0
14
54
2.60
2.70
2.6
2.1
12.4
11.6
%
0.09
14
47
11
37
2.98
2.69
1.9
2.1
—
—
—
0
0
28
147
1.92
2.65
1.1
1.2
1.2
0.5
u/ml
0.44
13
70
7
15
4.68
2.59
1.7
1.5
—
—
—
0
0
21
100
2.11
2.58
1.9
1.2
—
—
—
0
0
46
283
1.64
2.58
1.2
1.2
—
—
—
0
0
17
74
2.31
2.58
1.6
2.5
8941.6
802.3
e6/l
0.44
12
55
219
1779
1.25
2.54
1.4
1.4
—
—
—
0
0
23
115
2.01
2.51
1.2
1.2
136.0
137.5
nmol/l
0.05
23
115
11
40
2.76
2.37
1.0
1.0
—
—
—
0
0
11
40
2.76
2.37
1.0
1.0
—
—
—
0
0
11
40
2.76
2.37
1.0
1.0
—
—
—
0
0
7
17
4.13
2.36
1.6
1.2
—
—
—
0
0
30
169
1.78
2.32
2.3
2.3
687.2
610.9
ml
0.42
20
114
26
140
1.87
2.32
1.0
1.3
—
—
—
0
0
22
112
1.97
2.30
1.1
1.0
—
—
—
0
0
69
480
1.45
2.28
1.3
1.1
—
—
—
0
0
7
18
3.90
2.25
1.1
1.1
—
—
—
0
0
5
9
5.56
2.21
94.2
4.0
—
—
—
0
0
27
150
1.81
2.20
1.1
1.0
—
—
—
0
0
34
203
1.68
2.18
1.6
1.4
—
—
—
0
0
50
329
1.53
2.17
1.5
1.7
—
—
—
0
0
63
436
1.46
2.15
3.1
2.9
1.4
1.6
mmol/l
1.03
63
422
69
488
1.43
2.11
1.6
1.2
662.0
511.6
mg/l
0.64
63
464
8
25
3.21
2.09
1.0
1.3
—
—
mmol/l
—
0
0
9
31
2.91
2.07
1.6
1.5
117.6
121.4
ng/l
—
9
31
25
140
1.79
2.01
1.2
1.4
13.5
12.6
mmol/l
0.20
13
41
38
240
1.59
1.99
1.6
1.2
—
—
—
0
0
13
57
2.29
1.97
1.5
1.7
—
—
—
0
0
10
39
2.57
1.92
2.4
1.6
—
—
—
0
0
34
211
1.62
1.91
1.7
1.5
—
—
—
0
0
25
143
1.76
1.89
3.8
2.4
—
—
—
0
0
52
357
1.47
1.88
2.0
2.3
—
—
—
0
0
22
122
1.81
1.84
1.0
1.1
—
—
—
0
0
36
230
1.57
1.82
1.3
1.3
33.8
30.0
u/l
0.25
27
187
55
387
1.43
1.77
1.5
1.3
—
—
—
0
0
166
1370
1.23
1.74
2.6
2.2
11.8
12.7
nmol/l
0.73
144
1205
12
54
2.23
1.74
1.2
1.2
—
—
—
0
0
19
103
1.85
1.71
1.1
1.7
—
—
—
0
0
13
256
0.51
1.71
1.1
1.5
—
—
—
0
0
10
42
2.39
1.67
1.7
1.5
—
—
—
0
0
49
342
1.44
1.66
1.1
1.1
18.3
1714.4
iu/ml
0.52
13
76
11
49
2.25
1.63
1.3
1.6
31.6
26.0
g/l
—
6
36
1897
18456
1.12
1.63
24.4
14.9
38.7
39.7
%
4.20
1262
13170
13
250
0.52
1.60
1.2
1.4
—
—
—
0
0
8
32
2.50
1.59
3.5
6.4
—
—
—
0
0
13
249
0.52
1.59
1.1
1.4
—
—
—
0
0
6
20
3.00
1.58
1.2
1.3
131.4
135.2
mmol/l
—
6
15
31
199
1.56
1.57
1.1
1.1
—
—
—
0
0
20
114
1.76
1.56
1.0
1.0
—
—
—
0
0
61
450
1.36
1.54
2.8
2.0
11405.5
3684.4
u/l
0.52
21
190
7
27
2.60
1.51
1.3
1.3
—
—
—
0
0
18
101
1.79
1.49
2.1
2.5
—
—
—
0
0
20
116
1.73
1.48
2.6
2.6
36.2
38.4
%
—
9
42
6
22
2.73
1.43
1.3
1.3
—
640.5
—
0
9
54
397
1.37
1.41
3.8
3.2
1.0
0.8
nmol/l
0.54
39
308
59
441
1.35
1.39
3.8
3.6
26.0
26.7
mg/l
0.05
35
278
74
572
1.30
1.39
1.1
1.1
—
—
—
0
0
13
67
1.95
1.38
1.8
1.6
1.8
2.0
umol/l
1.07
13
61
5
17
2.94
1.36
1.0
1.1
3.6
5.2
nmol/l
—
5
17
19
112
1.70
1.35
1.5
1.3
—
—
—
0
0
24
151
1.60
1.34
1.3
1.2
—
—
—
0
0
55
410
1.35
1.33
3.2
3.0
7.4
7.6
mmol/l
0.21
55
397
95
764
1.25
1.32
2.4
2.5
—
—
—
0
0
57
428
1.34
1.32
1.6
1.3
5594.6
1031.5
e6/l
0.47
44
352
57
428
1.34
1.32
1.5
1.3
76.3
32.9
e6/l
0.32
42
332
241
2118
1.15
1.29
2.8
4.1
4.9
21.1
ug/l
3.14
200
1733
65
501
1.31
1.27
4.2
4.4
—
—
—
0
0
18
108
1.67
1.22
1.3
1.2
—
—
—
0
0
19
116
1.64
1.21
1.0
1.1
—
10.8
—
0
32
40
289
1.39
1.19
1.4
1.2
3.2
5.7
u/ml
1.08
20
122
8
38
2.11
1.18
1.5
1.2
—
—
—
0
0
12
64
1.88
1.18
1.2
1.1
—
—
—
0
0
16
94
1.71
1.17
1.2
1.1
—
15.1
u/ml
—
0
9
5
20
2.50
1.15
2.4
3.0
—
—
—
0
0
330
3630
0.89
1.11
2.8
3.0
0.7
0.8
ug/l
0.97
224
2376
43
320
1.35
1.09
1.4
1.2
24.7
41.4
u/l
0.95
38
271
292
2633
1.12
1.09
1.3
1.3
—
—
—
0
0
5
21
2.38
1.09
1.0
1.1
—
—
—
0
0
5
21
2.38
1.09
1.0
1.1
—
—
—
0
0
21
136
1.55
1.08
1.7
1.5
—
73.9
—
0
12
15
89
1.69
1.07
3.3
2.6
—
—
—
0
0
83
1012
0.81
1.07
1.9
1.7
—
—
—
0
0
154
1334
1.16
1.04
3.4
2.9
—
—
—
0
0
28
196
1.43
1.02
2.4
2.4
—
—
—
0
0
44
336
1.32
0.97
1.6
1.4
—
—
—
0
0
27
374
0.72
0.93
4.4
3.8
35.0
29.8
u/ml
0.21
27
362
37
487
0.76
0.92
1.9
2.0
—
—
—
0
0
10
55
1.82
0.92
1.1
1.7
—
—
—
0
0
10
55
1.82
0.92
1.3
1.5
—
—
—
0
0
39
297
1.32
0.89
1.2
1.3
—
—
—
0
0
36
274
1.32
0.84
1.1
1.1
—
—
—
0
0
12
190
0.63
0.82
1.0
1.0
—
—
—
0
0
27
197
1.37
0.82
1.3
1.3
—
—
—
0
0
31
232
1.34
0.81
1.8
2.2
—
—
—
0
0
36
276
1.31
0.80
1.1
1.1
—
—
—
0
0
29
385
0.75
0.79
1.3
1.2
—
—
—
0
0
12
74
1.62
0.78
2.7
2.3
—
—
—
0
0
12
74
1.62
0.78
2.2
1.8
—
—
—
0
0
7
123
0.57
0.78
1.0
1.1
—
—
—
0
0
651
6194
1.07
0.77
4.7
4.8
2.2
2.8
ug/l
1.06
581
5545
29
218
1.33
0.75
2.0
1.9
—
—
—
0
0
7
38
1.84
0.73
1.3
3.4
—
—
—
0
0
16
108
1.48
0.73
1.3
1.1
1.0
1.0
ratio
—
9
39
25
185
1.35
0.72
1.4
1.5
—
—
—
0
0
9
57
1.58
0.71
1.4
1.4
2.9
3.0
mmol/l
—
9
50
9
58
1.55
0.69
1.9
2.1
—
—
—
0
0
9
59
1.53
0.68
1.4
1.1
—
—
—
0
0
35
276
1.27
0.66
5.3
5.4
332.4
365.1
umol/l
0.53
30
241
63
532
1.19
0.65
1.7
1.8
—
—
—
0
0
30
233
1.29
0.64
1.9
1.5
0.2
0.3
nmol/l
2.03
19
176
64
542
1.19
0.64
1.8
1.8
—
—
—
0
0
22
163
1.35
0.64
2.5
2.0
1.0
2.3
u/field
—
10
64
5
29
1.73
0.64
1.2
1.4
—
—
—
0
0
8
129
0.62
0.63
1.0
1.4
—
1.4
—
0
6
25
190
1.32
0.62
1.2
1.2
—
—
—
0
0
10
63
1.59
0.61
1.4
1.7
—
—
—
0
0
63
536
1.18
0.61
1.8
1.8
—
—
—
0
0
58
490
1.19
0.60
1.8
1.9
—
—
—
0
0
573
5482
1.06
0.58
1.4
1.4
—
—
—
0
0
35
282
1.24
0.58
1.2
1.2
—
—
—
0
0
24
184
1.31
0.57
3.2
2.9
63.7
30.3
mg/l
0.26
17
135
15
106
1.42
0.57
3.0
1.6
0.9
2.2
u/field
—
10
77
63
540
1.17
0.57
1.8
1.8
—
—
—
0
0
16
115
1.39
0.56
13.1
12.7
905.9
832.9
nmol/l
0.32
16
110
49
411
1.20
0.56
2.2
3.3
61.7
1032.9
u/ml
0.92
44
383
6
37
1.62
0.55
1.2
1.1
—
—
—
0
0
10
66
1.52
0.52
1.0
1.0
—
—
—
0
0
19
143
1.33
0.52
1.2
1.1
31.1
40.2
mg/l
0.74
14
120
6
40
1.50
0.51
1.8
1.4
—
—
—
0
0
28
224
1.25
0.51
1.2
1.3
—
—
—
0
0
14
101
1.39
0.49
1.2
1.8
—
—
—
0
0
32
262
1.22
0.48
1.3
1.3
—
—
nmol/l
—
0
0
90
805
1.12
0.47
1.0
1.1
—
—
—
0
0
7
49
1.43
0.46
1.6
1.2
—
—
—
0
0
31
255
1.22
0.45
2.8
2.3
—
—
—
0
0
7
50
1.40
0.45
1.3
1.6
—
—
—
0
0
6
92
0.65
0.42
1.0
1.5
—
—
—
0
0
6
93
0.64
0.42
1.0
1.2
—
—
—
0
0
48
416
1.16
0.41
2.0
1.8
—
—
—
0
0
5
33
1.52
0.41
1.6
1.3
73.3
97.3
ng/l
—
5
25
28
233
1.20
0.38
2.0
1.9
—
—
—
0
0
17
135
1.26
0.35
1.4
1.5
2546.4
1840.0
ml
—
5
27
14
109
1.29
0.33
1.4
1.2
—
—
—
0
0
23
191
1.21
0.33
1.4
1.4
—
—
—
0
0
6
47
1.28
0.32
2.7
1.4
-0.8
1.3
mmol/l
—
6
42
44
497
0.88
0.32
1.3
1.3
—
—
—
0
0
12
92
1.31
0.31
1.1
1.2
—
—
—
0
0
34
298
1.14
0.28
1.1
1.1
—
10.2
—
0
17
31
271
1.15
0.27
1.4
1.3
—
—
—
0
0
80
744
1.08
0.24
2.8
3.5
155.2
4298.9
u/ml
0.62
68
627
12
97
1.24
0.23
26.0
12.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
2.1
—
0
5
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
29.2
—
0
5
6
48
1.25
0.20
1.2
2.0
—
—
—
0
0
7
62
1.13
0.17
3.0
2.0
—
—
—
0
0
17
148
1.15
0.17
1.5
1.5
0.9
1.0
g/l
0.47
17
148
5
70
0.71
0.16
1.2
1.4
—
—
—
0
0
12
102
1.18
0.15
1.2
1.4
6.1
6.0
mmol/l
0.07
12
97
25
231
1.08
0.10
2.6
2.6
—
—
—
0
0
21
228
0.92
0.10
1.1
1.1
—
—
—
0
0
105
1081
0.97
0.09
2.8
3.4
37.2
59.3
u/ml
1.16
99
1043
67
647
1.04
0.08
9.7
9.5
—
—
—
0
0
95
925
1.03
0.07
1.7
1.8
—
—
—
0
0
19
176
1.08
0.07
1.3
1.2
—
—
—
0
0
9
100
0.90
0.06
6.7
11.3
0.7
0.6
mmol/l
—
9
95
9
103
0.87
0.06
3.7
2.9
—
—
—
0
0
104
1025
1.02
0.03
3.8
3.4
—
—
—
0
0
163
1616
1.01
0.02
1.3
1.3
—
—
—
0
0
13
135
0.96
0.00
5.3
6.7
—
—
—
0
0
19
195
0.97
0.00
3.9
5.1
259.5
51.6
u/ml
—
8
54
13
132
0.98
0.00
1.3
1.5
87.6
275.3
pmol/l
—
5
42
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
253.7
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
0.00
1.2
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
5.0
—
—
—
0
0
9
94
0.96
0.00
3.7
3.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
0.1
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
0.00
1.4
1.1
—
—
—
0
0
6
65
0.92
0.00
1.3
1.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint L12_LICHSIMPANDPRURIGO and mortality.

Females

Parameter HR [95% CI] p-value
L12_LICHSIMPANDPRURIGO 1.42 [1.28, 1.58] < 0.001
Birth year 0.996 [0.99, 1.0] 0.288

During the follow-up period (1.1.1998 — 31.12.2019), 1395 out of 7396 females with L12_LICHSIMPANDPRURIGO died.

Males

Parameter HR [95% CI] p-value
L12_LICHSIMPANDPRURIGO 1.511 [1.36, 1.68] < 0.001
Birth year 0.988 [0.98, 1.0] 0.018

During the follow-up period (1.1.1998 — 31.12.2019), 1474 out of 6002 males with L12_LICHSIMPANDPRURIGO died.

Mortality risk

Mortality risk for people of age

years, who have L12_LICHSIMPANDPRURIGO.

N-year risk Females Males
1 0.126% 0.335%
5 0.773% 1.944%
10 1.863% 4.649%
15 3.905% 8.447%
20 7.104% 14.341%

Relationships between endpoints

Index endpoint: L12_LICHSIMPANDPRURIGO – Lichen simplex chronicus and prurigo

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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