No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
920 |
4. Check minimum number of eventsNone |
920 |
5. Include endpointsNone |
920 |
6. Filter based on genotype QC (FinnGen only) |
894 |
Control definitions (FinnGen only)
- Control exclude
- L12_DERMATITISECZEMA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L28
- Name in latin
- Prurigo nodularis
Similar endpoints
↥List of similar endpoints to
Prurigo nodularis
based on the number of shared cases.
Similar with more cases:
- Lichen simplex chronicus and prurigo
- Dermatitis and eczema
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6005 | 3529 | 2437 |
| Only index persons | 5439 | 3242 | 2197 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.10 | 0.07 |
| Only index persons | 0.10 | 0.12 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 62.03 | 62.76 | 60.90 |
| Only index persons | 61.16 | 61.95 | 59.99 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 894 | 553 | 341 |
| Unadjusted period prevalence (%) | 0.18 | 0.20 | 0.16 |
| Median age at first event (years) | 61.58 | 60.71 | 63.00 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 920
- Matched controls
- 9200
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L28.1
ICD-10 Finland
Prurigo nodularis
4503599627370496.0
307.7
908
*
D07AD01
ATC
clobetasol; topical
21.6
307.7
605
752
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
17.0
307.7
373
355
D09AB01
ATC
zinc bandage without supplements; topical
121.5
307.7
280
33
D07AC01
ATC
betamethasone; topical
15.0
307.7
738
1954
TQW80
NOMESCO Finland
Local dermatologic skincare
52.0
307.7
194
47
L30.9
ICD-10 Finland
Dermatitis, unspecified
14.7
307.7
470
612
D07AC13
ATC
mometasone; topical
11.2
299.2
635
1522
E0000UV, ,
ATC
15.1
296.7
765
2271
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
145.6
294.4
147
12
L30.3
ICD-10 Finland
Infective dermatitis
63.9
284.6
159
30
E000001, ,
ATC
9.1
246.4
442
850
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
9.9
231.5
339
512
L29.9
ICD-10 Finland
Pruritus, unspecified
31.8
211.4
141
52
D07BC01
ATC
betamethasone and antiseptics; topical
9.2
211.2
325
516
L20.0
ICD-10 Finland
Besnier prurigo
+∞
191.5
177
*
D07AB08
ATC
desonide; topical
9.7
188.8
261
361
D07BA04
ATC
hydrocortisone and antiseptics; topical
10.1
180.1
237
307
D02AX
ATC
Other emollients and protectives
25.0
176.3
128
59
XQ802
NOMESCO Finland
Epicutan test
31.7
161.6
107
38
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
+∞
143.6
134
*
D07AB02
ATC
hydrocortisone butyrate; topical
5.4
143.5
479
1536
E000002, ,
ATC
7.6
136.5
228
384
L30.0
ICD-10 Finland
Nummular dermatitis
15.5
125.8
114
83
D02AE01
ATC
carbamide; topical
8.8
120.4
167
226
R06AE07
ATC
cetirizine; oral
4.8
116.7
608
2650
D07CC01
ATC
betamethasone and antibiotics; topical
5.8
114.9
263
597
E000003, ,
ATC
12.0
113.3
121
115
A46
ICD-10 Finland
Erysipelas
5.2
106.9
283
725
R06AX27
ATC
desloratadine; oral
4.4
106.8
414
1430
L29.8
ICD-10 Finland
Other pruritus
38.8
105.0
65
18
L28.0
ICD-10 Finland
Lichen simplex chronicus
239.2
105.0
106
5
N05BB01
ATC
hydroxyzine; systemic
7.6
100.6
158
245
H02AB06
ATC
prednisolone; systemic
4.3
94.5
635
3156
E000007, ,
ATC
8.8
90.5
121
155
XQ848
NOMESCO Finland
Dermatological photography
11.9
85.5
90
83
L04AX03
ATC
methotrexate; systemic
5.1
81.6
202
481
D07AA02
ATC
hydrocortisone; topical
4.9
81.4
211
522
R06AE09
ATC
levocetirizine; oral
4.3
72.8
227
645
D07XC01
ATC
betamethasone; topical
4.6
70.7
200
527
L04AD01
ATC
ciclosporin; systemic
13.9
62.7
59
45
L28.2
ICD-10 Finland
Other prurigo
163.1
58.7
61
*
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
+∞
56.9
54
*
J01FF01
ATC
clindamycin; systemic
3.1
56.7
365
1625
S97
ICPC
Chronic ulcer skin
5.1
56.5
132
295
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
5.2
55.6
124
266
E000006, ,
ATC
5.2
53.1
118
252
L50.3
ICD-10 Finland
Dermatographic urticaria
13.3
49.8
48
38
R06AX22
ATC
ebastine; oral
3.3
49.4
235
868
XQ800
NOMESCO Finland
Prick test
5.4
49.0
104
213
L30.8
ICD-10 Finland
Other specified dermatitis
11.7
48.8
51
46
S76
ICPC
Skin infection other
5.1
45.2
103
224
L40.0
ICD-10 Finland
Psoriasis vulgaris
6.8
45.0
73
115
J01DB01
ATC
cefalexin; oral
4.6
43.8
839
6367
S87
ICPC
Dermatitis/atopic eczema
10.5
43.7
49
49
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
6.3
43.2
76
130
C03CA01
ATC
furosemide; systemic
2.6
40.9
382
1992
D11AH01
ATC
tacrolimus; topical
214.3
40.2
41
*
J45.0
ICD-10 Finland
Predominantly allergic asthma
3.9
39.8
130
373
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
8.3
39.6
53
67
D05BB02
ATC
acitretin; oral
8.6
39.3
51
62
S02
ICPC
Pruritus
6.3
39.1
68
115
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
6.2
36.6
65
112
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
35.7
523
3282
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
6.5
35.1
59
96
A10AE04
ATC
insulin glargine; parenteral
3.4
35.1
144
479
S29
ICPC
Skin symptom/complaint other
2.7
35.1
234
1024
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.2
33.7
97
253
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.9
33.2
187
747
J45.9
ICD-10 Finland
Asthma, unspecified
2.6
33.1
236
1064
N06AA12
ATC
doxepin; systemic
4.1
33.0
97
257
D07AC14
ATC
methylprednisolone aceponate; topical
4.6
32.4
80
185
L20
ICD-10 Finland
Atopic dermatitis
+∞
31.4
30
*
L04AA06
ATC
mycophenolic acid; systemic
8.4
30.9
41
51
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.5
30.5
235
1095
R60.0
ICD-10 Finland
Localized oedema
2.9
30.5
161
619
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
4.3
30.2
83
209
J01DA01
ATC
[U] cefalexin
2.3
30.1
631
4467
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.9
29.9
169
673
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
7.2
29.1
44
64
WXQ12
NOMESCO Finland
Psoralen - Ultraviolet A therapy with local sensitivisation
154.9
28.8
30
*
Z3231
NOMESCO Finland
Registered nurse
2.3
28.7
306
1642
H02AB04
ATC
methylprednisolone; systemic
2.7
28.5
182
771
S21
ICPC
Skin texture symptom/complaint
2.8
28.3
168
686
L20.8
ICD-10 Finland
Other atopic dermatitis
+∞
28.3
27
*
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
4.7
28.2
67
150
J04BA02
ATC
dapsone; oral
44.0
27.9
34
8
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
7.4
27.7
41
58
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
27.5
333
1877
L04AA01
ATC
[U] ciclosporin
10.7
27.2
30
29
A10AB05
ATC
insulin aspart; parenteral
3.4
26.9
106
342
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
6.7
26.6
43
67
E000004, ,
ATC
8.4
26.6
35
43
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.3
26.4
248
1254
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
+∞
26.2
25
*
D05AX02
ATC
calcipotriol; topical
4.8
26.0
60
131
Z2221
NOMESCO Finland
Medical doctor
2.2
25.9
302
1669
H02AB07
ATC
prednisone; oral
2.6
25.9
169
722
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
6.4
25.5
43
70
L28
ICD-10 Finland
Lichen simplex chronicus and prurigo
24.2
24.9
35
15
D05AX52
ATC
calcipotriol, combinations; topical
4.1
24.7
70
180
N17.9
ICD-10 Finland
Acute renal failure, unspecified
4.3
24.5
65
159
Z2446
NOMESCO Finland
Social worker
3.5
24.4
89
273
R50.9
ICD-10 Finland
Fever, unspecified
2.5
24.2
171
758
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.2
24.1
284
1568
J01CF05
ATC
flucloxacillin; systemic
3.5
24.1
88
270
Z49.1
ICD-10 Finland
Extracorporeal dialysis
8.8
23.8
30
35
S18
ICPC
Laceration/cut
2.0
23.7
472
3158
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.8
23.7
133
525
WW200
NOMESCO Finland
Immunization
5.5
23.5
46
87
L04AX01
ATC
azathioprine; systemic
4.4
23.4
60
143
TK800
NOMESCO Finland
Hemodialysis
6.3
23.0
39
64
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.5
22.8
163
725
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.1
22.7
276
1537
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
9.6
22.7
27
29
N02AX02
ATC
tramadol; systemic, rectal
2.0
22.7
447
2964
I50.9
ICD-10 Finland
Heart failure, unspecified
2.4
22.3
171
785
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.0
22.2
382
2411
L43.0
ICD-10 Finland
Hypertrophic lichen planus
22.1
22.2
32
15
D64.9
ICD-10 Finland
Anaemia, unspecified
2.7
22.0
133
545
Z3226
NOMESCO Finland
Physiotherapist
2.3
21.8
209
1056
103
Kela drug reimbursment
Diabetes, insulin-treated
2.1
21.6
300
1752
A11CC03
ATC
alfacalcidol; systemic
5.5
21.5
42
79
N06AB04
ATC
citalopram; systemic
2.2
21.5
231
1223
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
4.7
21.5
50
110
R03AC02
ATC
salbutamol; inhalant
2.0
21.4
531
3782
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
21.4
135
564
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.5
21.2
148
649
N03AX16
ATC
[U] pregabalin
2.1
21.1
260
1449
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
21.1
192
948
ZY010
NOMESCO Finland
Hospital outpatient
3.8
21.1
66
182
D11AX14
ATC
[U] tacrolimus
+∞
20.9
20
*
R03DC03
ATC
montelukast; oral
2.3
20.7
181
878
K08.3
ICD-10 Finland
Retained dental root
3.0
20.7
96
340
J45
ICD-10 Finland
Asthma
2.7
20.4
116
459
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.6
20.3
132
559
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.6
20.0
123
507
T90
ICPC
Diabetes non-insulin dependent
2.1
19.9
262
1492
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.3
19.9
176
858
6983A
ICD-9 Finland
Pruritus and related conditions, Lichenification and lichen simplex chronicus[PRURIGO NODULARIS HYDE]
+∞
19.9
19
*
L23.0
ICD-10 Finland
Allergic contact dermatitis due to metals
+∞
19.9
19
*
R4110
NOMESCO Finland
Physiotherapy
2.0
19.7
294
1750
S99
ICPC
Skin disease other
5.7
19.7
37
67
D06AX01
ATC
fusidic acid; topical
2.8
19.6
110
432
395
Kela drug reimbursment
Dupilumab
107.4
19.6
21
*
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
7.0
19.6
30
44
ZXE00
NOMESCO Finland
One hour or less
1.9
19.6
389
2550
I50.0
ICD-10 Finland
Congestive heart failure
2.9
19.3
97
359
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.9
19.2
98
366
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.2
19.2
52
129
L08.0
ICD-10 Finland
Pyoderma
23.1
19.1
27
12
WXQ10
NOMESCO Finland
Psoralen - Ultraviolet A therapy with systemic sensitivisation
+∞
18.8
18
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.5
18.8
133
586
L43.9
ICD-10 Finland
Lichen planus, unspecified
5.3
18.8
38
74
127
Kela drug reimbursment
Transplant complication
7.2
18.7
28
40
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
18.7
402
2693
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.4
18.7
152
713
D11AH05
ATC
dupilumab; topical
102.2
18.6
20
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.9
18.6
57
155
D07AC03
ATC
desoximetasone; topical
6.4
18.6
31
50
Z71.8
ICD-10 Finland
Other specified counselling
2.0
18.5
294
1783
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
5.6
18.5
35
64
D07XB05
ATC
dexamethasone; topical
4.8
18.4
42
91
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.2
18.3
170
843
N18.8
ICD-10 Finland
Other chronic renal failure
5.0
18.2
39
80
E66.8
ICD-10 Finland
Other obesity
3.4
18.0
66
203
I10
ICD-10 Finland
Essential (primary) hypertension
1.9
17.9
616
4757
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
17.8
368
2424
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.0
17.8
85
306
Z3229
NOMESCO Finland
Other healthcare associate professional
2.7
17.8
103
411
6918B
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[ECZEMA ATOPICUM]
+∞
17.8
17
*
J01AA07
ATC
tetracycline; systemic
2.3
17.8
153
735
J01CE08
ATC
benzathine benzylpenicillin; parenteral
13.4
17.5
30
23
J01MA02
ATC
ciprofloxacin; systemic
1.8
17.5
382
2558
R06AX13
ATC
loratadine; oral
2.3
17.3
152
735
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
17.2
260
1543
N06AX21
ATC
duloxetine; oral
2.4
17.2
132
602
RD210, ,
NOMESCO Finland
5.9
17.2
31
54
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.2
17.0
157
775
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
4.1
17.0
48
123
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
5.1
17.0
36
73
R06.0
ICD-10 Finland
Dyspnoea
1.9
16.9
276
1681
N06AX16
ATC
venlafaxine; oral
2.2
16.9
153
750
L98.1
ICD-10 Finland
Factitial dermatitis
64.6
16.8
19
*
E11
ICD-10 Finland
Type 2 diabetes mellitus
2.1
16.7
178
930
TKC20
NOMESCO Finland
Catheterisation of bladder
2.9
16.7
84
311
C03DA01
ATC
spironolactone; oral
2.3
16.7
141
671
B35.3
ICD-10 Finland
Tinea pedis
3.8
16.6
51
139
B86
ICD-10 Finland
Scabies
5.5
16.5
32
60
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.6
16.4
104
434
L13.0
ICD-10 Finland
Dermatitis herpetiformis
40.9
16.4
20
5
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
4.5
16.3
40
92
J45.8
ICD-10 Finland
Mixed asthma
4.3
16.2
42
101
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.8
16.2
88
340
L17
ICPC
Foot/toe symptom/complaint
1.9
16.2
284
1767
A10AC01
ATC
insulin (human); parenteral
2.7
16.1
93
370
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
16.1
430
3036
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
16.0
192
1049
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
15.9
375
2549
205
Kela drug reimbursment
Chronic hypertension
1.9
15.9
284
1775
R4120
NOMESCO Finland
Occupational therapy
2.8
15.8
81
303
M54.5
ICD-10 Finland
Low back pain
1.8
15.7
344
2287
D07CB01
ATC
triamcinolone and antibiotics; topical
5.5
15.5
30
56
K02.1
ICD-10 Finland
Caries of dentine
1.8
15.5
519
3897
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.6
15.5
51
146
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.3
15.5
60
191
A02BC02
ATC
pantoprazole; systemic
1.8
15.4
649
5205
X59
ICD-10 Finland
Exposure to unspecified factor
2.0
15.4
186
1017
C08CA13
ATC
lercanidipine; oral
2.1
15.4
164
856
SPAT1262
SPAT
Handing over of treatment supplies
2.0
15.3
185
1011
Z94.0
ICD-10 Finland
Kidney transplant status
13.3
15.2
26
20
ZXD05
NOMESCO Finland
Urgent procedure
1.8
15.1
290
1849
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.7
15.1
499
3722
WX203
NOMESCO Finland
Infraclavicular plexus blockade
4.7
15.0
35
77
WX110
NOMESCO Finland
Infiltration anesthesia
1.8
15.0
639
5119
N05CF01
ATC
zopiclone; oral
1.8
14.9
325
2151
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
14.8
271
1699
C07AB07
ATC
bisoprolol; oral
1.7
14.8
483
3581
A10AB04
ATC
insulin lispro; parenteral
4.0
14.8
42
108
UJF32
NOMESCO Finland
Coloscopy
1.8
14.8
267
1668
EBA00
NOMESCO Finland
Extraction of tooth
1.8
14.7
329
2191
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
21.5
14.7
21
10
J01DA09
ATC
[U] cefadroxil
1.9
14.7
255
1574
D11AH02
ATC
pimecrolimus; topical
+∞
14.6
14
*
SPAT1255
SPAT
Intravenous administration of medicine
2.7
14.6
80
310
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.8
14.5
77
293
A10BA02
ATC
metformin; oral
1.8
14.4
291
1878
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.4
14.4
53
163
R03BA02
ATC
budesonide; inhalant
2.0
14.4
182
1009
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.5
14.4
92
385
E66.00
ICD-10 Finland
Metabolic syndrome
2.9
14.4
69
249
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.8
14.4
269
1697
D01AE15
ATC
terbinafine; topical
2.6
14.3
84
337
WZC00
NOMESCO Finland
Treatment plan or consultation
1.8
14.3
337
2276
C08CA01
ATC
amlodipine; oral
1.7
14.1
391
2760
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
3.9
14.1
42
112
A12AA04
ATC
calcium carbonate; oral
5.9
14.0
25
43
M10.9
ICD-10 Finland
Gout, unspecified
2.7
14.0
77
299
M79.6
ICD-10 Finland
Pain in limb
1.7
14.0
400
2847
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.1
13.9
59
198
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
13.9
221
1322
A06AD11
ATC
lactulose; oral
2.0
13.9
164
886
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.6
13.9
83
336
L43.8
ICD-10 Finland
Other lichen planus
5.0
13.9
30
62
N06AX11
ATC
mirtazapine; oral
1.7
13.7
328
2219
J01AA04
ATC
lymecycline; systemic
2.2
13.7
123
599
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
2.2
13.7
118
565
SPF40
NOMESCO Finland
Removal and reattachment of crown or small bridge
5.0
13.6
29
59
EBA30
NOMESCO Finland
Extraction of root of tooth
2.7
13.6
76
297
XCK10
NOMESCO Finland
Photography of fundus of eye
2.3
13.6
108
499
AA1AD
NOMESCO Finland
CT of head and brain
1.8
13.6
274
1763
R06AX26
ATC
fexofenadine; oral
2.8
13.5
70
263
L28
ICPC
Limited function/disability (L)
1.9
13.5
186
1061
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.6
13.5
79
317
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
13.1
13.5
23
18
D01AC02
ATC
miconazole; topical
2.5
13.4
85
354
L30
ICD-10 Finland
Other dermatitis
4.8
13.4
30
64
R03BB04
ATC
tiotropium bromide; inhalant
2.3
13.3
111
523
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.5
13.3
88
374
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
6.0
13.1
23
39
JN3AD
NOMESCO Finland
Abdominal CT examination
2.2
13.1
121
595
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
3.1
13.0
54
179
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
3.5
13.0
45
133
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.3
13.0
100
455
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
17.0
13.0
20
12
RJ411, ,
NOMESCO Finland
19.4
12.9
19
10
N03AX12
ATC
[U] gabapentin; oral
2.0
12.9
169
946
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
12.9
308
2075
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
14.3
12.8
21
15
L29
ICD-10 Finland
Pruritus
9.9
12.8
25
26
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.8
12.8
66
248
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.8
12.8
66
248
J01FA01
ATC
erythromycin; systemic
2.2
12.7
123
616
SFA30
NOMESCO Finland
Three-surface restoration
1.7
12.7
389
2799
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.7
12.6
71
279
L26
ICD-10 Finland
Exfoliative dermatitis
+∞
12.5
12
*
L23.2
ICD-10 Finland
Allergic contact dermatitis due to cosmetics
+∞
12.5
12
*
N05BA04
ATC
oxazepam; oral
1.8
12.5
257
1656
S01GX01
ATC
cromoglicic acid; ophthalmic
1.9
12.5
178
1024
L23.9
ICD-10 Finland
Allergic contact dermatitis, unspecified cause
24.7
12.5
17
7
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
12.4
248
1586
D07AB01
ATC
clobetasone; topical
3.6
12.4
41
118
A28
ICPC
Limited function/disability NOS
1.9
12.3
178
1029
N02BE01
ATC
paracetamol; systemic, rectal
2.2
12.3
826
7348
R53
ICD-10 Finland
Malaise and fatigue
1.8
12.3
224
1392
A02BC01
ATC
omeprazole; systemic
1.7
12.3
267
1748
R52.2
ICD-10 Finland
Other chronic pain
3.3
12.2
47
149
N06AB03
ATC
fluoxetine; oral
2.1
12.2
132
690
RS221, ,
NOMESCO Finland
5.6
12.2
23
42
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
12.1
385
2788
H3603, E103,
ICD-10 Finland
18.3
12.1
18
10
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.1
12.0
50
166
J01MA12
ATC
levofloxacin; systemic
1.9
12.0
182
1067
N18.0
ICD-10 Finland
End-stage renal disease
9.4
12.0
24
26
XF600
NOMESCO Finland
Bloodpressure measurement
2.6
12.0
71
286
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
13.6
12.0
20
15
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
12.0
158
886
S01
ICPC
Pain/tenderness of skin
3.1
11.9
50
167
Z49.0
ICD-10 Finland
Preparatory care for dialysis
11.9
11.9
21
18
A10BH01
ATC
sitagliptin; oral
2.2
11.8
109
535
A10AE05
ATC
insulin detemir; parenteral
2.8
11.8
62
235
E0001A1, ,
ATC
5.2
11.8
24
47
E66.01
ICD-10 Finland
Obesity due to excess calories
2.3
11.8
91
415
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
11.8
182
1074
E66.9
ICD-10 Finland
Obesity, unspecified
3.4
11.8
43
132
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.1
11.7
115
578
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.5
11.7
77
326
SPAT1301
SPAT
No procedures
1.7
11.7
291
1971
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
16.7
11.7
18
11
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.1
11.7
126
657
TPH07
NOMESCO Finland
Cathetrisation of artery
2.1
11.6
119
609
WZC30
NOMESCO Finland
Teaching
1.9
11.6
153
857
W19
ICD-10 Finland
Unspecified fall
2.2
11.6
100
478
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.1
11.5
110
547
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.0
11.5
51
176
L50.9
ICD-10 Finland
Urticaria, unspecified
3.5
11.5
39
114
L12.0
ICD-10 Finland
Bullous pemphigoid
13.8
11.5
19
14
S88
ICPC
Dermatitis contact/allergic
4.6
11.5
27
60
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
11.4
173
1013
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.7
11.4
36
100
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.2
11.4
45
145
P01AB01
ATC
metronidazole; oral, rectal
1.6
11.4
373
2709
A02BC05
ATC
esomeprazole; systemic
1.6
11.3
380
2778
P76
ICPC
Depressive disorder
2.7
11.3
61
235
TQW99
NOMESCO Finland
Other minor procedure on skin
2.7
11.3
62
241
N05AH04
ATC
quetiapine; oral
1.9
11.2
161
926
C02AC05
ATC
moxonidine; oral
2.8
11.2
58
218
J01CF02
ATC
cloxacillin; systemic
4.2
11.2
30
74
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.4
11.2
76
327
J46
ICD-10 Finland
Status asthmaticus
4.0
11.2
32
83
L73.8
ICD-10 Finland
Other specified follicular disorders
12.9
11.2
19
15
V03AE02
ATC
sevelamer; oral
25.4
11.2
15
6
J45.1
ICD-10 Finland
Nonallergic asthma
2.4
11.1
77
334
G47.3
ICD-10 Finland
Sleep apnoea
1.8
11.1
210
1315
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.4
11.1
81
360
TGC00
NOMESCO Finland
Bronchial lavation
3.9
11.1
33
88
L03.9
ICD-10 Finland
Cellulitis, unspecified
4.3
11.1
28
66
ZXA00
NOMESCO Finland
Right side
1.7
11.0
262
1749
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.5
11.0
68
280
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.4
11.0
81
362
F34.1
ICD-10 Finland
Dysthymia
3.1
10.9
46
154
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
8.4
10.8
23
28
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.4
10.8
75
326
SAA02
NOMESCO Finland
Basic examination of mouth
1.6
10.8
563
4552
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
10.8
618
5113
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
4.6
10.8
25
55
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
10.8
157
908
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
5.7
10.7
20
36
WX002
NOMESCO Finland
Sedation and analgesia
1.8
10.7
190
1167
R03AC03
ATC
terbutaline; inhalant
2.0
10.7
132
722
137
Kela drug reimbursment
Uraemia requiring dialysis
13.1
10.7
18
14
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
4.2
10.7
28
68
T89
ICPC
Diabetes insulin dependent
3.1
10.7
45
151
RJ414, ,
NOMESCO Finland
60.7
10.6
12
*
L01.0
ICD-10 Finland
Impetigo [any organism] [any site]
5.3
10.6
21
40
U07
ICPC
Urine symptom/complaint other
2.4
10.6
78
348
R60.9
ICD-10 Finland
Oedema, unspecified
2.6
10.6
63
255
R42
ICD-10 Finland
Dizziness and giddiness
1.7
10.5
221
1425
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.1
10.5
107
546
C09AA02
ATC
enalapril; systemic
1.8
10.4
193
1200
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.7
10.4
248
1654
N06AB05
ATC
paroxetine; oral
2.6
10.4
63
257
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.1
10.4
44
148
SFA10
NOMESCO Finland
One-surface restoration
1.6
10.4
469
3653
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.1
10.3
103
521
SPAT1254
SPAT
Administration of medicine
1.9
10.3
146
836
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.7
10.3
54
205
QCA99
NOMESCO Finland
Other local destruction of skin of upper limb
23.7
10.3
14
6
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.7
10.2
242
1610
A04
ICPC
Weakness/tiredness general
1.9
10.2
138
779
J01FA06
ATC
roxithromycin; oral
1.6
10.1
366
2702
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.0
10.1
45
156
A10BH05
ATC
linagliptin; oral
2.6
10.0
58
231
R02
ICPC
Shortness of breath/dyspnoea
1.9
10.0
126
693
WX290
NOMESCO Finland
Other blockage of nerve
1.6
10.0
378
2820
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.8
10.0
181
1118
M04AA01
ATC
allopurinol; systemic
1.9
9.9
126
695
H02AB09
ATC
hydrocortisone; systemic
4.0
9.9
28
72
B05DA
ATC
Isotonic solutions
16.9
9.9
15
9
Z49.2
ICD-10 Finland
Other dialysis
16.9
9.9
15
9
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.4
9.8
67
289
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
4.6
9.8
23
51
C10AA05
ATC
atorvastatin; oral
1.6
9.8
398
3012
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.0
9.8
120
654
SPAT1310
SPAT
Counselling related to known health issue
1.6
9.8
281
1961
M54.4
ICD-10 Finland
Lumbago with sciatica
1.8
9.7
172
1053
N05BA01
ATC
diazepam; systemic, rectal
1.9
9.7
133
753
N06AA09
ATC
amitriptyline; systemic
2.1
9.7
102
527
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
9.2
9.5
19
21
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
15.2
9.5
15
10
K90.0
ICD-10 Finland
Coeliac disease
3.4
9.5
34
103
SFA20
NOMESCO Finland
Two-surface restoration
1.5
9.5
494
3941
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.8
9.5
161
974
B05DB
ATC
Hypertonic solutions
17.7
9.4
14
8
L23.3
ICD-10 Finland
Allergic contact dermatitis due to drugs in contact with skin
30.4
9.4
12
*
A10AE06
ATC
insulin degludec; parenteral
3.0
9.4
42
146
6929B
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[ECZEMA INFECTIOSUM]
+∞
9.4
9
*
6929X
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[DERMATITITIS ARTEFACTA NUD]
+∞
9.4
9
*
F60.9
ICD-10 Finland
Personality disorder, unspecified
5.2
9.4
19
37
E10
ICD-10 Finland
Type 1 diabetes mellitus
4.4
9.4
23
53
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.5
9.3
400
3056
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.7
9.3
51
198
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.2
9.3
83
402
R51.80
ICD-10 Finland
Headache
1.9
9.3
135
778
R03BA01
ATC
beclometasone; inhalant
1.9
9.2
133
764
R06AX18
ATC
acrivastine; oral
3.3
9.2
34
105
SPAT1263
SPAT
Sampling
1.6
9.2
368
2764
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
5.1
9.1
19
38
L04AD02
ATC
tacrolimus; systemic
8.4
9.1
19
23
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
11.6
9.1
16
14
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
9.1
198
1284
E87.6
ICD-10 Finland
Hypokalaemia
2.8
9.0
45
166
RJ420, ,
NOMESCO Finland
15.8
9.0
14
9
H3601, E103,
ICD-10 Finland
15.8
9.0
14
9
R03AC13
ATC
formoterol; inhalant
2.5
9.0
56
231
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
7.5
9.0
20
27
R03AK07
ATC
formoterol and budesonide; inhalant
1.7
8.9
178
1126
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
24.3
8.9
12
5
TNX34
NOMESCO Finland
Major custom molded cast, unspecified region
4.4
8.9
22
51
A10AB01
ATC
insulin (human); parenteral
3.2
8.9
35
113
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
4.7
8.9
20
43
ZX120
NOMESCO Finland
Intravenous
2.0
8.8
96
501
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
8.8
120
678
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
3.2
8.7
35
114
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
8.7
304
2208
NF1AA
NOMESCO Finland
Hip X-ray examination
2.0
8.7
95
496
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.1
8.7
89
454
A08
ICPC
Swelling
2.5
8.7
55
229
S01GX02
ATC
levocabastine; ophthalmic
2.5
8.7
54
223
L01.1
ICD-10 Finland
Impetiginization of other dermatoses
14.2
8.7
14
10
RJ410, ,
NOMESCO Finland
14.2
8.7
14
10
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.5
8.7
29
84
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
8.7
444
3504
V03AE01
ATC
polystyrene sulfonate; oral
6.7
8.7
21
32
L23.8
ICD-10 Finland
Allergic contact dermatitis due to other agents
50.5
8.7
10
*
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.2
8.7
74
352
H04.10
ICD-10 Finland
Dry eye syndrome
2.0
8.6
104
563
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
9.1
8.6
17
19
R03DC01
ATC
zafirlukast; oral
4.2
8.5
22
53
J01AA02
ATC
doxycycline; systemic
1.6
8.4
703
6147
R96
ICPC
Asthma
2.0
8.4
92
481
L23.1
ICD-10 Finland
Allergic contact dermatitis due to adhesives
90.9
8.4
9
*
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
2.9
8.4
40
144
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.0
8.4
97
517
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
8.4
389
3000
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.0
8.4
93
489
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.6
8.4
49
197
WXQ20
NOMESCO Finland
UVA broad spectrum light therapy
+∞
8.3
8
*
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.2
8.3
74
358
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
2.9
8.3
38
134
R03BA05
ATC
fluticasone; inhalant
1.7
8.3
161
1011
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
8.2
146
893
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
3.1
8.2
33
108
N06AB10
ATC
escitalopram; oral
1.7
8.2
171
1094
A03
ICPC
Fever
1.8
8.2
128
754
J04AB02
ATC
rifampicin; systemic
4.6
8.1
19
42
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.8
8.1
137
825
SPAT1229
SPAT
Assessment of need for aid
2.1
8.1
77
382
M25.5
ICD-10 Finland
Pain in joint
1.6
8.1
274
1972
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
33.7
8.1
10
*
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.7
8.1
185
1212
B03BA03
ATC
hydroxocobalamin; parenteral
2.3
8.1
59
263
J02AC01
ATC
fluconazole; systemic
1.5
8.1
329
2466
R03AK03
ATC
[U] fenoterol and ipratropium bromide
2.5
8.1
52
219
S06
ICPC
Rash localized
2.5
8.1
52
219
SPAT1240
SPAT
Therapeutic discussion
2.0
8.1
83
425
R4190
NOMESCO Finland
Nutritional therapy
2.9
8.0
37
131
H04AA01
ATC
glucagon; nasal, parenteral
4.2
8.0
21
51
L71.9
ICD-10 Finland
Rosacea, unspecified
3.5
8.0
27
79
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.8
8.0
127
752
N30.0
ICD-10 Finland
Acute cystitis
1.7
8.0
146
901
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
7.9
260
1857
S06.0
ICD-10 Finland
Concussion
1.9
7.9
98
536
A41.9
ICD-10 Finland
Sepsis, unspecified
2.8
7.9
38
138
U13
ICPC
Bladder symptom/complaint other
3.0
7.8
33
111
L02
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle
2.7
7.8
40
150
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.4
7.8
51
216
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
10.9
7.8
14
13
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
7.8
108
612
N07BB01
ATC
disulfiram; oral
2.7
7.8
41
156
L85.3
ICD-10 Finland
Xerosis cutis
7.0
7.8
18
26
M48.0
ICD-10 Finland
Spinal stenosis
1.8
7.8
128
765
ZXA05
NOMESCO Finland
Left side
1.6
7.7
232
1622
B81
ICPC
Anaemia vit B12/folate deficiency
2.7
7.7
40
151
L23.5
ICD-10 Finland
Allergic contact dermatitis due to other chemical products
45.4
7.7
9
*
ZST00
NOMESCO Finland
Procedure related to previous procedure classified in chapter T
45.4
7.7
9
*
B01AB05
ATC
enoxaparin; parenteral
1.5
7.7
291
2141
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.7
7.6
140
863
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.5
7.6
48
200
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.5
7.6
48
200
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.3
7.6
57
257
N02BF02
ATC
pregabalin; oral
2.3
7.6
59
270
R03AK08
ATC
formoterol and beclometasone; inhalant
2.6
7.6
43
170
B03XA02
ATC
darbepoetin alfa; parenteral
3.4
7.6
26
77
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.0
7.6
32
108
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
10.1
7.5
14
14
P01BA02
ATC
hydroxychloroquine; oral
2.0
7.5
79
407
A10BK03
ATC
empagliflozin; oral
1.9
7.4
97
539
WX320
NOMESCO Finland
Spinalanesthesy
1.6
7.4
223
1560
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.9
7.4
88
475
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
3.0
7.3
32
110
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
11.0
7.3
13
12
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
11.0
7.3
13
12
69798
ICD-8 Finland
Lichen, Alius definitus
+∞
7.3
7
*
6918C
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[DIATHESIS (CONSTITUTIO) ATOPICA]
+∞
7.3
7
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.6
7.3
209
1444
A10AA01, ,
ATC
3.4
7.3
26
79
N19
ICD-10 Finland
Unspecified kidney failure
2.6
7.3
40
156
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.0
7.3
82
434
RJ421, ,
NOMESCO Finland
15.9
7.2
11
7
ZXD35
NOMESCO Finland
Usual procedure
2.8
7.2
35
128
R04.0
ICD-10 Finland
Epistaxis
2.1
7.2
71
358
R11
ICD-10 Finland
Nausea and vomiting
2.0
7.2
80
422
RS211, ,
NOMESCO Finland
20.2
7.1
10
5
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
7.1
360
2801
AN1
HP
Coronary angiography
1.8
7.1
107
622
K07
ICPC
Swollen ankles/oedema
2.4
7.1
49
213
NHQ40
NOMESCO Finland
Amputation of toe
3.8
7.1
21
56
GD1AD
NOMESCO Finland
Thorax CT examination
2.2
7.1
57
265
A10AA02, ,
ATC
2.9
7.1
33
118
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.1
7.1
66
326
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.1
7.0
64
313
A07EC01
ATC
sulfasalazine; oral, rectal
2.0
7.0
75
390
JN4BD
NOMESCO Finland
Extensive body CT
1.8
7.0
98
558
M79.7
ICD-10 Finland
Fibromyalgia
2.7
7.0
36
136
N05AX08
ATC
risperidone; systemic
2.0
7.0
79
419
KMAK, ,
NOMESCO Finland
1.4
7.0
419
3367
134
Kela drug reimbursment
General erythroderma
13.9
6.9
11
8
R01AD08
ATC
fluticasone; nasal
1.5
6.9
233
1668
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.8
6.9
105
613
N03AE01
ATC
clonazepam; systemic
2.2
6.9
55
255
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
6.9
358
2797
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
6.9
239
1722
C09BA02
ATC
enalapril and diuretics; systemic
2.0
6.8
79
422
H62.0*A46
ICD-10 Finland
Otitis externa in erysipelas
11.0
6.8
12
11
I50
ICD-10 Finland
Heart failure
2.8
6.8
32
115
E78.00
ICD-10 Finland
Familial hypercholesterolaemia
2.5
6.8
43
180
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.0
6.8
68
345
C03AA03
ATC
hydrochlorothiazide; oral
1.9
6.8
91
511
H3602, E103,
ICD-10 Finland
40.4
6.8
8
*
R52.9
ICD-10 Finland
Pain, unspecified
1.9
6.8
85
467
J01MA14
ATC
moxifloxacin; systemic
1.9
6.8
81
438
L03
ICPC
Low back symptom/complaint
1.5
6.7
233
1675
JN4AD
NOMESCO Finland
Body CT examination
1.9
6.7
92
519
X57
ICD-10 Finland
Unspecified privation
3.3
6.7
25
78
L25.9
ICD-10 Finland
Unspecified contact dermatitis, unspecified cause
22.7
6.7
9
*
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.6
6.7
198
1376
SPAT1260
SPAT
Consultation of another employee
1.6
6.7
151
984
SPAT1211
SPAT
Application of soft bandage
1.9
6.7
80
433
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
6.6
255
1874
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
3.0
6.6
29
100
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
7.9
6.6
14
18
L01BA01
ATC
methotrexate; systemic
2.6
6.6
36
140
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.8
6.6
100
584
D72.1
ICD-10 Finland
Eosinophilia
10.1
6.5
12
12
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.9
6.5
29
101
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
2.6
6.5
37
147
UJD02
NOMESCO Finland
Gastroscopy
2.3
6.5
49
222
A01AB09
ATC
miconazole; local oral
1.9
6.5
83
459
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
3.6
6.5
21
60
QXA70
NOMESCO Finland
Guidance related to rash and skin care
70.3
6.4
7
*
8070/3-C44.7
ICD-O-3
Squamous cell carcinoma, NOS, of skin of lower limb and hip
70.3
6.4
7
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.7
6.4
115
704
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
2.9
6.4
29
102
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
4.1
6.4
17
42
B01AC04
ATC
clopidogrel; oral
1.6
6.4
150
987
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.1
6.4
59
291
3AC01, ,
NOMESCO Finland
6.6
6.3
15
23
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.5
6.3
39
161
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
3.5
6.3
21
61
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.2
6.3
51
238
196
Kela drug reimbursment
Paricalcitol and cinacalcet
9.3
6.3
12
13
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.1
6.3
55
265
D01BA02
ATC
terbinafine; oral
1.5
6.3
215
1540
SFA40
NOMESCO Finland
Restoration involving the entire crown of the tooth
1.5
6.3
193
1351
R03DA04
ATC
theophylline; systemic, rectal
2.2
6.3
50
232
6983B
ICD-9 Finland
Pruritus and related conditions, Lichenification and lichen simplex chronicus[NEURODERMATITIS CIRCUMSCRIPTA]
+∞
6.3
6
*
WXQ24
NOMESCO Finland
UVB/UVA light therapy
+∞
6.3
6
*
69299
ICD-8 Finland
Other eczema and dermatitis, Due to other and unspecified cause
+∞
6.3
6
*
WXQ26
NOMESCO Finland
UVB broad spectrum light therapy
+∞
6.3
6
*
Z50.1
ICD-10 Finland
Other physical therapy
2.2
6.2
54
259
J01CE02
ATC
phenoxymethylpenicillin; oral
1.4
6.2
566
4864
F61.0
ICD-10 Finland
Mixed personality disorders
5.1
6.2
18
36
RS220, ,
NOMESCO Finland
5.1
6.2
18
36
A10BX01
ATC
guar gum; oral
2.4
6.2
43
188
J01DA06
ATC
[U] cefuroxime
1.7
6.2
122
767
SPAT1151
SPAT
Treatment of major wounds
5.4
6.2
17
32
L89
ICD-10 Finland
Decubitus ulcer and pressure area
3.4
6.2
21
62
-1, ,
NOMESCO Finland
1.5
6.2
258
1925
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
2.4
6.1
41
176
CKC12
NOMESCO Finland
Photocoagulation of retina
2.4
6.1
41
176
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.2
6.1
48
221
S22.3
ICD-10 Finland
Fracture of rib
2.0
6.1
66
344
TQW40
NOMESCO Finland
Remowal of suture of skin
2.0
6.1
66
344
A02BC03
ATC
lansoprazole; oral
1.5
6.1
258
1929
N05BA12
ATC
alprazolam; oral
1.8
6.1
93
544
R23.3
ICD-10 Finland
Spontaneous ecchymoses
3.2
6.0
23
73
D01AA02
ATC
natamycin; topical
3.2
6.0
23
73
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
10.1
6.0
11
11
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.0
6.0
60
304
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.4
6.0
38
159
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
5.6
6.0
16
29
E66
ICD-10 Finland
Obesity
2.3
6.0
46
210
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
228
385
7.54
136.12
1.6
1.2
1002.36
153.13
u/ml
3.25
222
345
673
3804
3.87
75.56
10.5
5.8
0.27
0.18
e9/l
12.12
615
3325
369
1520
3.38
67.56
1.4
1.2
2.36
1.55
u/ml
0.48
84
405
615
3443
3.37
66.53
10.6
5.7
3.63
2.79
%
9.58
587
3205
335
1327
3.40
64.96
1.6
1.5
2.68
2.50
g/l
0.72
166
797
620
3527
3.32
64.46
10.6
5.8
24.18
27.54
%
13.13
591
3301
609
3475
3.23
62.03
10.6
5.6
59.65
57.40
%
5.15
584
3251
698
4330
3.54
61.35
12.6
8.9
4.36
4.08
e9/l
2.85
639
3791
128
284
5.07
55.20
1.6
3.0
3.80
3.56
g/l
1.44
117
256
200
624
3.82
55.18
2.1
3.3
67.49
66.48
g/l
1.03
184
564
128
285
5.06
54.97
1.6
3.0
7.43
7.48
g/l
0.11
117
256
128
285
5.06
54.97
1.6
3.0
—
—
—
0
0
122
264
5.17
54.13
1.6
3.1
2.88
3.05
g/l
1.02
111
235
121
265
5.11
52.91
1.6
3.1
10.37
10.35
g/l
0.01
109
236
195
630
3.66
50.80
9.9
7.2
11.93
9.92
mmol/l
2.64
183
599
100
201
5.46
48.08
1.7
3.5
0.00
0.00
g/l
-0.00
93
187
100
202
5.43
47.81
1.7
3.5
0.00
0.00
g/l
-0.00
93
187
103
214
5.29
47.72
1.7
3.4
0.00
0.02
g/l
0.50
96
198
109
240
5.02
47.22
1.7
3.5
0.45
1.25
g/l
1.50
98
213
385
1912
2.74
46.93
2.9
2.1
3.00
3.08
mg/l
0.22
329
1625
106
230
5.08
46.70
1.7
3.2
38.45
37.82
g/l
0.50
95
201
269
1173
2.83
41.35
3.5
2.3
11.25
13.04
umol/l
3.71
255
1086
544
3348
2.53
40.70
6.4
4.6
34.44
35.32
g/l
3.07
512
3129
239
1010
2.85
38.69
3.8
2.3
20.18
23.01
%
2.16
208
859
248
1079
2.78
37.89
3.6
2.3
2.27
2.34
g/l
0.93
231
992
228
974
2.78
35.87
10.1
5.1
1.12
1.03
mmol/l
3.94
214
884
507
3149
2.36
35.32
4.2
2.7
122.08
140.02
ug/l
0.72
463
2877
206
846
2.85
34.84
2.7
2.8
6.50
9.22
umol/l
1.57
173
731
600
4034
2.40
34.42
7.0
6.4
10.81
11.57
umol/l
0.98
572
3836
205
846
2.83
34.31
2.3
2.5
1.93
1.84
%
0.76
180
755
778
5944
3.00
33.42
10.3
7.5
84.03
78.80
u/l
2.48
741
5561
263
1249
2.55
33.13
3.8
3.3
0.81
0.81
mmol/l
0.46
249
1167
491
3178
2.17
28.83
2.3
2.0
90.45
95.20
pmol/l
1.52
249
1614
194
850
2.63
28.43
2.8
4.0
242.58
255.21
u/l
0.37
188
805
367
2138
2.19
27.99
4.6
3.0
0.39
0.50
e6/l
0.55
287
1631
300
1620
2.26
27.51
3.7
2.5
5.97
6.06
e6/l
0.03
270
1474
390
2341
2.16
27.42
4.7
3.2
29.41
100.53
e6/l
1.71
310
1808
186
817
2.60
27.01
5.2
3.3
—
—
—
0
0
734
5661
2.47
26.98
5.8
4.0
17.12
12.62
mm/h
10.94
697
5203
331
1882
2.19
26.55
1.7
1.5
19.16
21.06
nmol/l
1.76
292
1574
73
185
4.20
26.27
1.3
1.5
0.24
0.24
g/l
0.22
67
179
431
2720
2.10
26.26
5.4
3.7
66.26
109.41
e6/l
0.62
317
1942
74
191
4.13
25.99
1.3
1.5
1.23
1.17
g/l
0.92
69
183
165
696
2.67
25.93
7.1
3.4
1.86
2.17
mmol/l
0.43
141
575
559
3897
2.11
25.93
11.1
6.6
1.20
1.21
mmol/l
3.73
473
3301
519
3550
2.06
24.97
9.9
5.8
1.20
1.21
mmol/l
2.53
481
3223
154
639
2.69
24.95
2.3
2.4
75.81
71.76
e9/l
0.71
109
488
159
681
2.61
24.13
2.0
2.0
350.99
373.13
nmol/l
0.64
143
623
322
1893
2.08
23.02
5.7
3.7
93.16
90.31
%
1.26
312
1846
327
1952
2.05
22.28
3.6
2.6
5266.17
6851.55
umol/l
0.22
282
1696
607
4498
2.03
22.16
7.4
4.7
7.35
6.72
mmol/l
6.01
574
4245
270
1509
2.12
21.91
2.8
3.0
2.46
2.45
mmol/l
0.22
231
1335
233
1247
2.16
21.04
2.3
1.8
—
—
—
0
0
461
3148
1.93
20.92
2.8
2.2
74.05
78.31
nmol/l
2.79
426
2791
130
543
2.62
20.60
1.9
1.6
—
—
—
0
0
267
1522
2.06
20.32
1.8
1.7
1243.87
1199.20
nmol/l
0.28
200
1136
63
175
3.79
19.95
1.3
1.3
—
—
—
0
0
370
2385
1.92
19.64
3.9
3.1
6.40
7.27
mmol/l
4.09
310
1982
358
2288
1.92
19.46
4.1
3.1
444.42
212.67
mg/l
0.43
248
1408
75
242
3.29
18.92
1.3
1.3
0.14
1.38
u/ml
—
5
22
371
2424
1.89
18.66
3.9
3.2
33.54
32.66
u/l
0.13
340
2300
647
5050
1.95
18.51
6.5
4.4
3352.78
3335.84
e6/l
—
9
80
507
3662
1.86
18.48
16.6
14.8
1.25
1.25
inr
0.06
172
1055
136
616
2.42
18.06
5.8
3.5
121.63
82.66
ng/l
2.79
121
537
174
882
2.20
17.73
2.0
1.8
—
—
—
0
0
144
680
2.33
17.37
3.3
2.1
30.02
38.19
u/l
1.33
123
571
352
2316
1.84
16.91
4.0
3.0
2411.04
1311.73
ng/l
1.66
306
1975
172
884
2.16
16.87
2.0
1.8
—
—
—
0
0
123
550
2.43
16.76
2.7
2.8
10.41
10.62
g/l
0.19
107
504
45
112
4.17
16.56
1.2
1.2
—
—
—
0
0
61
189
3.39
16.40
3.6
2.9
1.96
1.62
mg/l
1.45
56
172
361
2420
1.81
16.13
4.8
3.7
20.21
8.14
mg/mmol
1.47
253
1462
226
1316
1.95
15.65
3.4
2.6
0.98
1.23
e6/l
0.66
115
741
357
2407
1.79
15.50
3.0
2.4
56.54
91.43
u/l
0.53
323
2212
498
3701
1.75
15.35
6.6
5.1
0.00
0.00
estimate
0.50
114
673
353
2381
1.78
15.24
2.6
2.2
232.64
201.18
u/l
0.22
329
2247
144
718
2.19
15.15
2.4
2.1
0.20
0.21
g/l
0.90
128
677
85
335
2.69
15.01
1.6
1.9
1.59
1.53
g/l
0.25
70
294
499
3744
1.73
14.56
5.0
3.7
0.00
0.00
estimate
0.50
98
654
245
1496
1.87
14.55
4.4
3.9
553.05
413.71
ng/l
0.17
202
1207
213
1243
1.93
14.54
3.5
2.9
3.49
2.71
e6/l
0.57
103
674
50
148
3.52
14.43
1.4
1.3
—
—
—
0
0
50
148
3.52
14.43
1.4
1.3
—
—
—
0
0
847
7520
2.59
14.37
28.3
14.3
26.49
24.19
mg/l
1.15
743
5952
33
72
4.72
14.32
1.1
1.1
—
—
—
0
0
388
2728
1.73
14.23
3.6
3.5
2.35
2.36
mmol/l
0.65
346
2405
43
116
3.84
14.20
1.7
1.4
96.06
124.11
u/ml
—
8
19
26
46
5.79
14.20
1.4
1.8
13.50
9.92
umol/l
0.22
20
27
164
882
2.05
14.11
8.9
7.8
5.04
5.14
kpa
0.59
155
846
164
883
2.04
14.06
8.9
7.7
11.18
12.03
kpa
1.46
154
846
45
127
3.67
13.94
9.8
7.2
328.75
548.11
iu/ml
—
8
19
63
221
2.99
13.80
2.4
1.6
—
—
—
0
0
203
1196
1.89
13.35
2.2
2.0
30.15
29.57
s
0.72
197
1164
162
885
2.01
13.29
8.9
7.8
0.34
1.33
mmol/l
1.71
132
704
57
195
3.05
13.04
2.0
1.6
—
—
—
0
0
487
3698
1.67
13.02
5.1
3.7
0.00
0.00
estimate
0.74
118
728
86
366
2.49
12.98
4.4
2.4
1.12
1.19
%
0.30
86
366
22
19
11.83
12.35
2.0
1.3
9.64
7.72
ug/l
1.12
22
19
692
5856
1.73
11.48
4.9
4.0
14.65
14.90
pmol/l
1.95
634
5282
34
91
3.84
11.38
1.0
1.0
8.88
1.64
u/ml
—
8
37
50
172
3.02
11.35
2.8
3.3
30.00
35.64
umol/l
1.04
42
154
76
326
2.45
11.27
2.0
1.9
3.34
2.32
ug/l
0.33
69
285
48
163
3.05
11.14
4.3
2.4
15.60
15.73
%
0.07
31
80
296
2047
1.66
10.87
1.8
1.6
1.55
1.35
mmol/l
2.57
240
1702
27
63
4.39
10.82
1.0
1.0
1.12
0.53
u/ml
0.42
21
26
55
206
2.78
10.72
1.1
1.2
—
—
—
0
0
31
83
3.83
10.38
1.0
1.1
1.40
1.51
u/ml
0.04
18
40
55
210
2.72
10.34
1.5
1.5
0.05
29.36
iu/ml
—
8
41
201
1268
1.75
10.31
1.4
1.3
40.89
35.04
iu/ml
0.16
46
414
49
177
2.87
10.22
1.5
1.4
—
—
—
0
0
59
235
2.61
10.22
2.2
4.7
45.78
76.54
mg/l
0.58
41
195
59
235
2.61
10.22
2.2
4.7
43.07
42.31
mg/l
0.02
41
194
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
60
241
2.59
10.21
2.8
2.6
0.26
0.37
u/ml
2.02
27
137
58
231
2.61
10.05
2.2
4.6
—
1.79
—
0
24
120
653
1.96
9.83
2.7
3.0
325.80
212.24
ng/l
0.95
108
605
38
122
3.21
9.70
1.4
1.2
—
—
—
0
0
37
117
3.25
9.68
1.4
1.2
321.22
286.13
u/ml
0.22
27
64
860
7910
2.34
9.61
32.1
16.8
3.99
3.97
mmol/l
0.51
848
7699
46
167
2.85
9.52
2.8
2.2
125.27
128.85
g/l
0.42
37
122
858
7891
2.30
9.47
31.6
16.6
138.82
139.70
mmol/l
17.72
845
7691
51
197
2.68
9.39
1.2
1.2
35.70
42.09
u/ml
—
5
9
796
7136
1.86
9.39
8.3
5.8
43.25
40.07
mmol/mol
10.45
750
6582
583
4848
1.55
9.13
4.1
3.1
70.96
51.32
u/l
3.97
537
4491
48
183
2.71
9.07
1.3
1.2
5.32
3.01
u/ml
—
5
21
25
64
3.99
8.91
1.2
1.4
1.58
1.32
nmol/l
0.52
20
54
39
134
3.00
8.91
3.6
3.2
4.70
4.10
e9/l
1.03
39
134
48
186
2.67
8.80
1.3
1.2
2.28
12.69
u/ml
—
6
34
32
100
3.28
8.55
1.4
1.5
—
—
—
0
0
12
6
20.24
8.48
13.0
4.2
4.87
7.50
mmol/l
—
12
6
46
179
2.65
8.37
1.7
1.6
—
—
—
0
0
780
7008
1.74
8.36
6.1
4.8
1.85
2.10
mu/l
0.83
729
6364
39
139
2.89
8.36
4.1
3.4
61.28
57.76
%
1.04
39
139
132
783
1.80
8.25
2.0
1.8
1.79
1.48
%
2.58
108
668
242
1690
1.59
8.16
2.0
1.7
1.55
1.21
mg/l
0.40
192
1318
67
318
2.19
7.91
1.7
2.2
37.01
39.93
u/l
0.73
56
282
36
127
2.91
7.87
1.6
1.5
—
—
—
0
0
118
686
1.83
7.87
3.0
2.5
8.53
7.34
ug/l
0.14
109
608
36
128
2.89
7.77
1.9
1.6
—
—
—
0
0
30
96
3.20
7.74
6.6
6.1
11.82
11.85
mg/l
0.01
30
87
182
1200
1.64
7.73
1.3
1.3
15.99
12.38
u/ml
0.19
69
450
12
8
15.17
7.73
1.0
1.0
—
—
—
0
0
33
112
3.02
7.72
1.4
1.5
—
—
—
0
0
44
175
2.59
7.68
1.7
1.6
—
—
—
0
0
87
462
1.98
7.63
1.8
1.6
—
—
—
0
0
86
456
1.98
7.58
4.7
3.2
4.43
4.52
pmol/l
0.33
77
400
29
94
3.15
7.33
1.2
1.3
—
—
—
0
0
132
812
1.73
7.25
2.3
2.2
138.44
127.69
ug/g
0.21
103
642
55
251
2.27
7.15
2.3
2.9
—
—
—
0
0
30
102
3.01
7.02
1.7
1.5
—
—
—
0
0
441
3575
1.45
7.01
3.2
2.6
—
—
—
0
0
39
155
2.58
6.84
3.1
1.6
1.02
0.82
nmol/l
0.95
32
131
253
1848
1.51
6.80
3.1
2.3
—
—
—
0
0
509
4256
1.44
6.74
3.3
2.7
—
—
—
0
0
26
84
3.16
6.63
1.8
1.6
—
—
—
0
0
30
106
2.89
6.58
1.8
1.5
—
—
—
0
0
860
8082
1.98
6.29
17.8
10.4
25.78
25.55
u/l
0.14
843
7793
81
458
1.84
5.91
1.8
1.5
—
—
—
0
0
45
206
2.25
5.84
2.5
2.3
340.20
67.95
ug/min
0.87
24
119
46
213
2.22
5.82
1.5
1.8
—
—
—
0
0
107
660
1.70
5.81
6.9
3.7
1.21
1.23
mmol/l
1.88
97
574
265
2007
1.45
5.81
6.1
4.0
0.00
0.01
estimate
0.88
106
658
154
1042
1.57
5.79
1.5
1.4
—
—
—
0
0
96
583
1.72
5.52
2.8
2.8
59.47
63.81
ml/min/173m2
0.46
49
231
782
7220
1.55
5.36
26.4
13.4
76.34
78.68
ml/min/173m2
1.82
675
5992
20
64
3.17
5.21
1.5
1.6
—
—
—
0
0
35
153
2.34
5.08
1.9
1.5
—
—
—
0
0
14
28
5.06
4.95
1.6
1.3
—
—
—
0
0
12
20
6.06
4.92
1.1
1.0
—
—
—
0
0
43
208
2.12
4.92
2.1
2.2
86.56
91.62
%
0.60
43
200
8
7
11.51
4.79
5.5
5.9
—
—
—
0
0
227
1726
1.42
4.75
1.8
1.7
480.42
22096753.68
pmol/l
1.27
182
1412
350
2862
1.36
4.71
5.7
4.0
—
—
—
0
0
15
43
3.53
4.62
1.3
1.6
—
—
—
0
0
38
180
2.16
4.60
1.3
1.3
—
—
—
0
0
15
44
3.45
4.48
1.3
1.5
—
—
—
0
0
19
65
2.96
4.46
1.2
1.4
20.29
30.99
%
—
10
42
15
45
3.37
4.34
1.2
1.2
—
—
—
0
0
8
9
8.95
4.28
1.1
1.1
—
—
—
0
0
37
183
2.06
4.04
1.2
1.1
—
—
—
0
0
74
457
1.67
4.04
5.6
3.4
2.75
1.93
mmol/l
1.21
59
339
871
8352
1.80
4.01
40.9
21.1
260.48
249.38
e9/l
5.05
859
8138
16
53
3.05
3.98
1.3
1.5
—
—
—
0
0
871
8355
1.80
3.97
40.8
21.1
4.32
4.46
e12/l
10.40
855
8118
871
8357
1.79
3.93
41.2
21.2
129.81
134.55
g/l
15.23
864
8229
42
220
1.95
3.93
1.3
1.4
212.66
303.86
ug/g
2.97
29
119
23
94
2.48
3.91
1.6
1.6
54.17
65.23
%
0.50
12
62
27
119
2.31
3.90
1.7
1.5
—
—
—
0
0
27
119
2.31
3.90
1.7
1.5
—
—
—
0
0
795
7474
1.47
3.88
5.6
4.6
6.34
5.98
mmol/l
5.72
721
6765
815
7702
1.51
3.86
5.9
5.0
2.64
2.75
mmol/l
2.71
741
7066
870
8350
1.77
3.85
41.4
21.2
38.81
39.84
%
4.62
826
7774
801
7545
1.48
3.84
5.3
4.5
4.56
4.68
mmol/l
2.56
740
6978
29
581
0.48
3.79
2.1
1.7
—
—
—
0
0
41
216
1.94
3.78
1.3
1.2
—
—
—
0
0
359
3021
1.31
3.76
5.6
3.7
48.08
51.46
ng/l
0.08
273
2184
23
96
2.43
3.75
1.6
1.8
31.13
32.05
pg
0.36
23
96
41
217
1.93
3.73
1.6
1.4
—
—
—
0
0
35
176
2.03
3.68
1.8
1.7
2.85
5.77
iu/l
—
10
58
14
40
3.54
3.61
1.4
1.7
—
—
—
0
0
17
63
2.73
3.50
1.1
1.0
—
—
—
0
0
6
6
10.05
3.50
2.5
1.2
—
—
—
0
0
794
7496
1.43
3.47
5.2
4.5
1.43
1.49
mmol/l
3.79
719
6878
40
216
1.89
3.45
1.3
1.2
—
—
—
0
0
20
84
2.41
3.24
1.5
1.3
58171.55
116553.63
e6/l
0.33
11
48
13
39
3.37
3.23
1.2
1.4
155.14
165.22
mmol/24h
0.18
13
39
16
61
2.65
3.14
1.1
1.2
1.08
1.01
u/ml
0.02
11
30
13
44
2.98
3.14
1.0
1.2
—
—
—
0
0
13
44
2.98
3.14
1.0
1.2
—
—
—
0
0
35
187
1.91
3.14
1.9
1.7
8956.44
14926.12
e6/l
0.65
25
147
769
7249
1.37
3.13
4.8
4.0
1.45
1.29
mmol/l
5.69
696
6592
57
354
1.65
3.10
4.0
3.5
46.50
46.72
%
0.02
57
349
10
25
4.03
3.09
1.1
1.0
2032.90
1484.32
miu/ml
—
10
25
16
62
2.61
3.05
1.4
1.4
—
—
—
0
0
16
62
2.61
3.05
1.4
1.4
—
—
—
0
0
16
62
2.61
3.05
1.4
1.4
—
—
—
0
0
56
348
1.65
3.04
1.4
1.3
—
—
—
0
0
7
12
5.87
3.02
1.0
1.0
—
—
—
0
0
9
21
4.32
3.00
1.0
1.2
—
—
—
0
0
49
302
1.66
2.77
2.8
1.7
—
—
—
0
0
16
66
2.45
2.72
2.2
2.5
720.09
566.12
ml
0.65
11
42
41
242
1.73
2.71
1.3
1.3
28.35
30.58
iu/l
0.18
36
208
20
92
2.20
2.68
1.6
1.3
1921.00
1701.97
e6/l
0.14
15
64
13
49
2.68
2.63
1.1
1.1
—
—
—
0
0
13
49
2.68
2.63
1.1
1.1
—
—
—
0
0
11
36
3.08
2.57
1.0
1.0
—
—
—
0
0
13
50
2.62
2.54
1.1
1.1
—
—
—
0
0
13
50
2.62
2.54
1.1
1.1
—
—
—
0
0
13
50
2.62
2.54
1.1
1.1
—
—
—
0
0
8
21
3.83
2.46
1.0
1.2
—
—
—
0
0
32
182
1.79
2.42
1.4
1.5
—
—
—
0
0
18
83
2.19
2.42
1.7
1.6
—
—
—
0
0
18
83
2.19
2.42
1.7
1.6
—
—
—
0
0
72
1007
0.69
2.38
4.9
4.6
31.13
32.54
%
0.55
47
679
5
8
6.28
2.37
2.4
2.0
—
—
—
0
0
12
46
2.63
2.36
1.2
1.2
—
—
—
0
0
44
276
1.62
2.36
2.6
1.6
—
—
—
0
0
201
1659
1.27
2.30
5.2
4.1
1.02
1.02
kg/l
0.12
25
253
10
34
2.96
2.28
1.0
1.1
—
—
—
0
0
11
41
2.70
2.21
2.1
1.3
77.00
84.76
umol/l
0.42
11
41
65
454
1.46
2.18
2.8
2.1
11.11
12.48
nmol/l
0.64
54
396
21
108
1.97
2.16
1.0
1.1
18.63
33.86
iu/ml
—
8
21
69
489
1.44
2.15
3.1
2.5
29.90
23.49
au/ml
—
5
33
10
36
2.80
2.14
1.5
1.4
—
—
—
0
0
10
36
2.80
2.14
1.5
1.4
—
—
—
0
0
16
75
2.15
2.09
1.6
1.5
—
—
—
0
0
17
82
2.09
2.07
1.5
1.4
—
—
—
0
0
14
63
2.24
2.01
2.0
1.5
—
—
—
0
0
8
28
2.87
1.86
1.0
1.1
237.13
215.29
iu/ml
—
8
28
49
335
1.49
1.86
1.1
1.0
—
—
—
0
0
16
80
2.02
1.80
3.9
2.3
—
—
—
0
0
20
109
1.85
1.78
1.3
1.1
—
—
—
0
0
8
30
2.68
1.72
1.5
1.4
—
—
—
0
0
8
30
2.68
1.72
1.5
1.4
—
—
—
0
0
8
30
2.68
1.72
1.5
1.4
—
—
—
0
0
6
19
3.17
1.66
1.2
1.1
—
—
—
0
0
6
19
3.17
1.66
1.5
1.1
—
—
—
0
0
28
173
1.64
1.65
3.8
3.2
0.72
0.84
nmol/l
0.91
18
137
46
319
1.47
1.65
2.7
3.4
242.47
1378.00
u/ml
1.13
38
271
109
873
1.28
1.61
2.9
4.3
4.55
27.25
ug/l
1.71
92
737
64
476
1.37
1.57
1.2
1.2
75.40
139.82
iu/ml
0.77
19
189
28
176
1.61
1.56
1.2
1.3
—
—
—
0
0
12
57
2.12
1.55
1.3
1.1
—
—
—
0
0
20
115
1.76
1.53
1.1
1.1
—
—
—
0
0
12
58
2.08
1.49
1.2
1.2
15.00
11.80
u/l
0.39
12
51
5
16
3.14
1.44
1.2
1.1
—
—
—
0
0
12
59
2.05
1.44
1.0
1.1
—
—
—
0
0
34
229
1.50
1.43
1.6
1.8
—
—
—
0
0
31
210
1.49
1.29
1.2
1.2
—
—
—
0
0
5
18
2.79
1.28
1.2
1.2
107.00
113.38
%
—
5
13
65
503
1.31
1.27
10.6
7.0
24.47
24.70
mmol/l
0.22
59
478
24
154
1.57
1.27
1.9
3.5
54.72
2274.51
u/ml
0.78
24
149
8
37
2.17
1.21
1.1
1.3
—
—
—
0
0
26
177
1.48
1.08
1.3
1.3
192.83
253.78
miu/ml
—
6
79
7
32
2.20
1.08
1.0
1.2
—
—
—
0
0
10
52
1.93
1.06
1.5
1.5
—
—
—
0
0
7
34
2.07
1.03
1.6
3.1
205.43
205.41
u/l
—
7
34
18
115
1.58
1.00
1.6
1.5
—
—
—
0
0
26
182
1.44
0.97
1.7
1.8
—
—
—
0
0
17
109
1.57
0.94
1.1
1.1
—
—
—
0
0
8
42
1.91
0.88
1.0
1.3
—
—
—
0
0
8
42
1.91
0.88
1.0
1.2
—
—
—
0
0
8
42
1.91
0.88
1.0
1.2
—
—
—
0
0
8
43
1.87
0.87
1.3
3.5
—
—
—
0
0
11
64
1.73
0.86
1.2
1.1
—
—
—
0
0
18
120
1.51
0.86
3.6
2.0
89.99
1646.67
u/l
—
7
45
13
81
1.61
0.81
1.2
1.4
30.19
29.04
u/l
—
8
66
14
89
1.58
0.81
3.4
3.7
—
—
—
0
0
8
47
1.71
0.80
1.1
1.7
—
—
—
0
0
6
34
1.77
0.76
1.0
1.2
—
—
—
0
0
6
34
1.77
0.76
1.0
1.2
—
—
—
0
0
6
34
1.77
0.76
5.0
4.7
—
—
—
0
0
7
38
1.85
0.73
1.0
1.2
—
—
—
0
0
7
38
1.85
0.73
1.0
1.2
—
—
—
0
0
15
101
1.49
0.70
1.5
1.2
2.25
7.36
u/ml
—
8
44
9
58
1.56
0.70
1.3
1.7
1.02
1.04
g/l
—
9
58
14
94
1.50
0.67
1.2
1.1
—
—
—
0
0
16
112
1.44
0.63
1.1
1.1
—
11.13
—
0
6
14
96
1.47
0.61
1.4
1.2
2.75
2.64
u/ml
—
8
28
0
20
0.00
0.60
0.0
2.0
—
1.23
—
0
20
15
105
1.44
0.60
1.2
1.2
—
—
—
0
0
15
106
1.42
0.58
1.2
1.2
—
—
—
0
0
15
106
1.42
0.58
1.2
1.2
—
—
—
0
0
6
35
1.72
0.57
1.0
2.1
1.35
6.79
nmol/l
—
6
29
6
35
1.72
0.57
1.2
3.2
822.67
800.83
u/ml
—
6
35
5
86
0.58
0.56
1.2
1.4
—
—
—
0
0
5
87
0.57
0.56
1.2
1.4
—
—
—
0
0
5
87
0.57
0.56
1.2
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
6
37
1.63
0.55
1.2
1.1
—
—
—
0
0
6
37
1.63
0.55
1.2
1.1
—
—
—
0
0
109
979
1.13
0.55
11.4
6.8
—
—
—
0
0
6
39
1.54
0.53
1.2
1.1
—
—
—
0
0
7
46
1.53
0.48
1.0
1.8
—
—
—
0
0
7
48
1.46
0.47
1.1
1.6
12.51
14.11
umol/l
—
7
48
57
501
1.15
0.42
1.7
1.8
—
—
—
0
0
5
33
1.52
0.41
1.0
1.1
—
—
—
0
0
26
213
1.23
0.41
2.2
1.8
—
—
—
0
0
8
60
1.34
0.40
1.1
1.0
—
—
—
0
0
236
2245
1.07
0.37
4.7
5.0
1.95
2.60
ug/l
1.53
214
1997
6
42
1.43
0.35
1.0
1.1
—
—
—
0
0
23
190
1.22
0.35
4.1
3.4
15.39
27.50
mg/l
1.83
14
117
10
73
1.37
0.34
1.1
1.1
—
—
—
0
0
6
88
0.68
0.33
1.2
1.3
6.94
7.54
mmol/l
—
6
75
10
75
1.34
0.30
1.1
1.1
—
—
—
0
0
13
104
1.25
0.26
1.2
1.2
—
—
—
0
0
8
67
1.20
0.26
2.8
2.4
—
—
—
0
0
13
105
1.24
0.25
1.2
1.2
—
—
—
0
0
13
105
1.24
0.25
1.2
1.2
—
—
—
0
0
49
447
1.10
0.23
1.6
1.7
—
—
—
0
0
5
38
1.32
0.23
2.2
2.5
—
—
—
0
0
11
136
0.81
0.23
1.4
1.5
—
—
—
0
0
5
40
1.25
0.22
1.0
1.1
117.08
168.17
pmol/l
—
5
40
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
2722.00
—
0
8
136
1300
1.05
0.21
2.9
3.1
0.71
0.76
ug/l
0.26
103
855
6
48
1.25
0.20
1.0
1.0
—
—
—
0
0
11
90
1.22
0.19
2.1
1.5
—
—
—
0
0
186
1798
1.04
0.18
4.3
4.3
21.08
21.37
%
0.09
82
863
5
68
0.73
0.17
2.2
2.2
13.94
13.32
%
—
5
68
22
244
0.90
0.14
1.3
1.4
—
—
—
0
0
7
90
0.78
0.14
1.3
1.5
—
—
—
0
0
12
104
1.16
0.12
2.7
2.3
23.37
20.67
mg/l
—
7
26
17
154
1.11
0.10
2.1
1.2
28.25
895.28
e6/l
0.68
12
128
17
154
1.11
0.10
1.8
1.1
207.08
27.69
e6/l
0.40
12
122
13
117
1.11
0.08
1.5
1.2
0.55
0.61
nmol/l
0.44
13
110
7
65
1.08
0.08
1.0
1.2
—
—
—
0
0
41
418
0.98
0.01
3.3
3.4
33.24
70.74
u/ml
1.38
36
402
11
104
1.06
0.01
4.3
2.6
107.09
105.42
mmol/l
0.93
11
104
11
104
1.06
0.01
4.3
2.6
4.15
4.04
mmol/l
0.51
11
104
27
269
1.00
0.00
1.5
1.8
24.22
2.83
mg/l
0.59
22
204
22
219
1.00
0.00
1.2
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
0.00
1.4
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
97.20
—
0
5
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
10
100
1.00
-0.00
1.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
113
1130
1.00
-0.00
1.4
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_PRURIGONOD and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_PRURIGONOD | 1.628 [1.43, 1.85] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.366 |
During the follow-up period (1.1.1998 — 31.12.2019), 716 out of 2849 females with L12_PRURIGONOD died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_PRURIGONOD | 1.578 [1.36, 1.83] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.012 |
During the follow-up period (1.1.1998 — 31.12.2019), 583 out of 1993 males with L12_PRURIGONOD died.
Mortality risk
Mortality risk for people of age
years, who have L12_PRURIGONOD.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.155% | 0.343% |
| 5 | 1.021% | 1.905% |
| 10 | 2.627% | 4.714% |
| 15 | 4.688% | 9.11% |
| 20 | 8.065% | 14.938% |
Relationships between endpoints
↥Index endpoint: L12_PRURIGONOD – Prurigo nodularis
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data