Lichen simplex chronicus

L12_LICHENSIMPLEX

lichen disease: a long-term skin condition that mainly affects the skin of the genitals. It usually causes itching and white patches to appear on the affected skin.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L28.0
  • Hospital discharge: ICD-9 6983B|697X
  • Hospital discharge: ICD-8 6983
  • Cause of death: ICD-10 L28.0
  • Cause of death: ICD-9 6983B|697X
  • Cause of death: ICD-8 6983

2 out of 7 registries used, show all original rules.

1328

4. Check minimum number of events

None

1328

5. Include endpoints

None

1328

6. Filter based on genotype QC (FinnGen only)

1284

Control definitions (FinnGen only)

Control exclude
L12_DERMATITISECZEMA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L28
Name in latin
Lichen simplex chronicus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8813 4491 4275
Only index persons 7913 4095 3818
Unadjusted period prevalence (%)
Whole population 0.12 0.13 0.12
Only index persons 0.15 0.15 0.15
Median age at first event (years)
Whole population 53.53 54.18 52.91
Only index persons 52.84 53.38 52.26

-FinnGen-

Key figures

All Female Male
Number of individuals 1284 707 577
Unadjusted period prevalence (%) 0.26 0.25 0.26
Median age at first event (years) 53.75 52.87 54.82

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1328
Matched controls
13280
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L30.9
ICD-10 Finland
Dermatitis, unspecified
10.7
307.7
577
887
D07AC01
ATC
betamethasone; topical
9.4
307.7
943
2753
D07AD01
ATC
clobetasol; topical
14.4
307.7
739
1063
L28.0
ICD-10 Finland
Lichen simplex chronicus
16384.0
307.7
1245
6
D09AB01
ATC
zinc bandage without supplements; topical
72.7
307.7
249
42
D07AC13
ATC
mometasone; topical
7.3
296.1
782
2166
E0000UV, ,
ATC
6.2
233.4
879
3188
D07BC01
ATC
betamethasone and antiseptics; topical
7.1
210.3
391
739
TQW80
NOMESCO Finland
Local dermatologic skincare
25.7
198.3
141
61
L30.3
ICD-10 Finland
Infective dermatitis
26.7
198.2
139
58
XQ802
NOMESCO Finland
Epicutan test
27.1
184.1
128
52
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
7.8
181.1
285
447
E000001, ,
ATC
5.4
177.4
469
1213
L20.0
ICD-10 Finland
Besnier prurigo
+∞
176.0
165
*
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
5.9
159.1
350
763
D07AB02
ATC
hydrocortisone butyrate; topical
4.0
132.7
584
2163
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
43.5
123.4
74
18
D07CC01
ATC
betamethasone and antibiotics; topical
4.9
122.5
329
838
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
6.1
106.9
207
393
D07AB08
ATC
desonide; topical
5.4
105.8
238
518
L28.1
ICD-10 Finland
Prurigo nodularis
368.2
103.7
103
*
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
+∞
96.0
91
*
E000002, ,
ATC
4.9
92.1
232
553
L30.0
ICD-10 Finland
Nummular dermatitis
9.4
82.1
101
115
D02AE01
ATC
carbamide; topical
5.6
79.0
161
318
D07BA04
ATC
hydrocortisone and antiseptics; topical
4.7
77.7
199
478
D07XC01
ATC
betamethasone; topical
4.0
77.5
261
771
A46
ICD-10 Finland
Erysipelas
3.6
77.0
305
1006
L28
ICD-10 Finland
Lichen simplex chronicus and prurigo
23.3
77.0
56
25
L20.8
ICD-10 Finland
Other atopic dermatitis
+∞
66.2
63
*
L40.0
ICD-10 Finland
Psoriasis vulgaris
5.9
60.7
115
211
L30.8
ICD-10 Finland
Other specified dermatitis
10.5
57.0
64
64
69830
ICD-8 Finland
Pruritus and related conditions, Lichenification and lichen simplex chronicus
+∞
56.7
54
*
R06AE07
ATC
cetirizine; oral
2.5
56.0
666
3850
E000003, ,
ATC
6.1
55.2
99
172
N05BB01
ATC
hydroxyzine; systemic
4.6
52.8
132
308
E000006, ,
ATC
4.5
52.5
137
331
D02AX
ATC
Other emollients and protectives
8.4
52.0
69
86
XQ848
NOMESCO Finland
Dermatological photography
7.3
50.4
76
110
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.6
49.9
379
1762
L43.8
ICD-10 Finland
Other lichen planus
9.0
48.5
61
71
D07AA02
ATC
hydrocortisone; topical
3.2
47.9
215
752
D05AX52
ATC
calcipotriol, combinations; topical
4.5
47.3
123
296
XQ800
NOMESCO Finland
Prick test
4.4
47.1
127
314
L29.9
ICD-10 Finland
Pruritus, unspecified
8.4
46.8
62
77
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
7.8
46.5
66
89
E000007, ,
ATC
4.9
46.5
106
229
L43.9
ICD-10 Finland
Lichen planus, unspecified
7.5
46.1
67
93
L20
ICD-10 Finland
Atopic dermatitis
+∞
44.0
42
*
D05BB02
ATC
acitretin; oral
7.5
43.9
64
89
H02AB06
ATC
prednisolone; systemic
2.2
43.1
693
4397
6983B
ICD-9 Finland
Pruritus and related conditions, Lichenification and lichen simplex chronicus[NEURODERMATITIS CIRCUMSCRIPTA]
+∞
42.9
41
*
D07AC14
ATC
methylprednisolone aceponate; topical
4.6
42.0
104
240
L29.8
ICD-10 Finland
Other pruritus
13.9
40.9
38
28
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
+∞
40.8
39
*
R06AX27
ATC
desloratadine; oral
2.3
38.3
419
2254
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.7
36.1
218
891
L28.2
ICD-10 Finland
Other prurigo
65.1
33.2
38
6
S29
ICPC
Skin symptom/complaint other
2.3
28.8
270
1343
J01DA01
ATC
[U] cefalexin
1.9
28.7
855
6394
R06AE09
ATC
levocetirizine; oral
2.4
28.5
217
985
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
+∞
28.2
27
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.4
27.6
207
933
S02
ICPC
Pruritus
4.6
27.6
66
148
D07XB05
ATC
dexamethasone; topical
5.5
27.5
54
102
J01DB01
ATC
cefalexin; oral
2.3
26.6
1116
9281
J01FF01
ATC
clindamycin; systemic
2.0
25.6
387
2294
D07CB01
ATC
triamcinolone and antibiotics; topical
6.1
25.2
44
74
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.8
24.4
76
208
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
5.6
24.3
46
84
C03CA01
ATC
furosemide; systemic
1.9
23.8
388
2349
D11AH01
ATC
tacrolimus; topical
88.4
23.7
26
*
S87
ICPC
Dermatitis/atopic eczema
6.0
22.7
40
68
L23.0
ICD-10 Finland
Allergic contact dermatitis due to metals
233.9
22.7
23
*
L04AX03
ATC
methotrexate; systemic
2.5
21.9
156
683
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
21.2
471
3121
L50.3
ICD-10 Finland
Dermatographic urticaria
6.2
21.2
36
59
E000004, ,
ATC
6.2
20.4
35
58
S76
ICPC
Skin infection other
3.1
20.0
86
290
R06.0
ICD-10 Finland
Dyspnoea
1.8
19.6
358
2226
H02AB04
ATC
methylprednisolone; systemic
2.1
19.2
205
1062
SPAT1263
SPAT
Sampling
1.7
19.2
543
3827
R03AC02
ATC
salbutamol; inhalant
1.7
19.0
712
5400
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
18.8
388
2500
WXQ12
NOMESCO Finland
Psoralen - Ultraviolet A therapy with local sensitivisation
70.9
18.7
21
*
L43
ICD-10 Finland
Lichen planus
6.9
18.7
29
43
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
18.5
185
933
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
18.5
550
3918
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
18.2
600
4385
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
6.4
18.1
30
48
L43.0
ICD-10 Finland
Hypertrophic lichen planus
13.9
17.8
30
22
D01AE15
ATC
terbinafine; topical
2.6
17.7
111
457
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
17.2
17.4
27
16
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.1
17.3
180
921
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
2.2
17.3
156
755
E66.01
ICD-10 Finland
Obesity due to excess calories
2.3
17.2
135
616
L04AD01
ATC
ciclosporin; systemic
5.0
17.2
37
76
S97
ICPC
Chronic ulcer skin
2.7
17.1
95
368
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
17.1
249
1435
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
3.5
17.0
58
169
S21
ICPC
Skin texture symptom/complaint
2.1
17.0
181
934
UJF32
NOMESCO Finland
Coloscopy
1.8
17.0
347
2218
WQ020, ,
NOMESCO Finland
+∞
16.7
16
*
L23.2
ICD-10 Finland
Allergic contact dermatitis due to cosmetics
+∞
16.7
16
*
N02AX02
ATC
tramadol; systemic, rectal
1.6
16.6
565
4133
L23.8
ICD-10 Finland
Allergic contact dermatitis due to other agents
91.2
16.6
18
*
E66.8
ICD-10 Finland
Other obesity
2.8
16.4
87
329
I83.9
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
2.2
15.9
150
739
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.1
15.7
153
763
S06
ICPC
Rash localized
2.8
15.7
80
297
S18
ICPC
Laceration/cut
1.6
15.4
581
4335
L40.9
ICD-10 Finland
Psoriasis, unspecified
5.3
15.4
31
60
R02
ICPC
Shortness of breath/dyspnoea
2.0
15.1
172
909
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.8
14.9
252
1517
B35.3
ICD-10 Finland
Tinea pedis
3.0
14.9
65
221
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
4.6
14.8
35
78
D05AX02
ATC
calcipotriol; topical
3.2
14.7
59
191
D11AX14
ATC
[U] tacrolimus
+∞
14.6
14
*
D11AH02
ATC
pimecrolimus; topical
+∞
14.6
14
*
L17
ICPC
Foot/toe symptom/complaint
1.7
14.6
360
2410
Z49.1
ICD-10 Finland
Extracorporeal dialysis
5.5
14.5
28
52
WQ021, ,
NOMESCO Finland
151.6
14.5
15
*
M79.7
ICD-10 Finland
Fibromyalgia
3.2
14.4
59
193
103
Kela drug reimbursment
Diabetes, insulin-treated
1.7
14.3
347
2312
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.1
14.1
151
780
R60.0
ICD-10 Finland
Localized oedema
2.0
14.0
156
817
M79.6
ICD-10 Finland
Pain in limb
1.6
13.8
529
3932
L29.2
ICD-10 Finland
Pruritus vulvae
6.3
13.8
23
37
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.4
13.7
101
448
R06AX13
ATC
loratadine; oral
1.9
13.6
188
1059
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
13.6
906
7616
R50.9
ICD-10 Finland
Fever, unspecified
1.9
13.6
189
1067
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.1
13.6
37
92
ZY010
NOMESCO Finland
Hospital outpatient
2.7
13.6
72
273
H02AB07
ATC
prednisone; oral
1.9
13.4
176
975
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.7
13.4
321
2126
K13.29
ICD-10 Finland
Indefinite leukoplakia
5.4
13.3
26
49
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
13.3
304
1989
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.0
13.3
157
840
A10AB05
ATC
insulin aspart; parenteral
2.3
13.1
105
483
J01CE08
ATC
benzathine benzylpenicillin; parenteral
9.4
13.0
26
28
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
13.0
570
4351
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
3.9
12.9
38
100
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
12.9
362
2490
L23.9
ICD-10 Finland
Allergic contact dermatitis, unspecified cause
22.8
12.9
18
8
SAA02
NOMESCO Finland
Basic examination of mouth
1.5
12.9
830
6883
A02BC02
ATC
pantoprazole; systemic
1.6
12.8
864
7234
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
12.8
290
1891
J01MA02
ATC
ciprofloxacin; systemic
1.6
12.6
480
3543
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.2
12.6
51
166
SPAT1260
SPAT
Consultation of another employee
1.8
12.5
215
1297
L23.1
ICD-10 Finland
Allergic contact dermatitis due to adhesives
131.2
12.5
13
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
12.4
292
1919
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
12.4
365
2539
P01AB01
ATC
metronidazole; oral, rectal
1.5
12.3
498
3721
R03BA05
ATC
fluticasone; inhalant
1.8
12.3
227
1396
J02AC01
ATC
fluconazole; systemic
1.5
12.3
473
3496
A02BC03
ATC
lansoprazole; oral
1.6
12.2
369
2581
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
12.1
238
1489
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
12.1
156
858
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.8
12.0
186
1086
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.8
12.0
60
221
J01DA09
ATC
[U] cefadroxil
1.6
11.9
332
2276
J45.1
ICD-10 Finland
Nonallergic asthma
2.3
11.8
96
444
N02BE01
ATC
paracetamol; systemic, rectal
1.8
11.8
1153
10432
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
11.7
504
3806
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.8
11.6
59
219
E66.0
ICD-10 Finland
Obesity due to excess calories
5.3
11.6
23
44
6929B
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[ECZEMA INFECTIOSUM]
+∞
11.5
11
*
SPAT1153
SPAT
Removal of sutures
1.6
11.4
390
2798
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
5.4
11.4
22
41
L13.0
ICD-10 Finland
Dermatitis herpetiformis
15.2
11.3
18
12
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
11.3
166
953
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
11.2
320
2201
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
4.6
11.2
26
57
L03.9
ICD-10 Finland
Cellulitis, unspecified
3.8
11.1
33
88
R60.9
ICD-10 Finland
Oedema, unspecified
2.5
11.0
71
297
S01
ICPC
Pain/tenderness of skin
2.6
10.8
62
245
N06AX21
ATC
duloxetine; oral
1.9
10.8
155
883
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
3.0
10.7
48
166
J01AA02
ATC
doxycycline; systemic
1.5
10.6
988
8669
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.1
10.6
104
520
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.1
10.5
96
466
K59.09
ICD-10 Finland
Constipation, unspecified
2.2
10.5
85
393
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
10.4
467
3536
SPAT1262
SPAT
Handing over of treatment supplies
1.7
10.4
217
1377
SPAT1301
SPAT
No procedures
1.5
10.4
364
2617
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
10.4
438
3276
PHD76
NOMESCO Finland
Resection of long saphenous vein
2.4
10.4
70
299
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.7
10.3
57
221
G47.3
ICD-10 Finland
Sleep apnoea
1.6
10.3
295
2026
N06AB04
ATC
citalopram; systemic
1.6
10.3
252
1666
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.9
10.2
46
160
WZA90
NOMESCO Finland
Other medical or dental certificate
1.6
10.1
285
1950
A11CC03
ATC
alfacalcidol; systemic
3.4
10.0
36
109
S08
ICPC
Skin colour change
2.4
10.0
71
310
B01AB05
ATC
enoxaparin; parenteral
1.5
10.0
385
2822
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.5
9.9
33
95
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
9.9
476
3648
T90
ICPC
Diabetes non-insulin dependent
1.6
9.8
289
1996
K02.1
ICD-10 Finland
Caries of dentine
1.4
9.8
723
6009
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.7
9.7
221
1433
J01CF05
ATC
flucloxacillin; systemic
2.2
9.7
81
380
A10AE05
ATC
insulin detemir; parenteral
2.3
9.7
73
328
395
Kela drug reimbursment
Dupilumab
55.4
9.7
11
*
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.8
9.6
167
1006
TK800
NOMESCO Finland
Hemodialysis
3.5
9.6
33
97
SPAT1254
SPAT
Administration of medicine
1.7
9.6
172
1046
Z94.0
ICD-10 Finland
Kidney transplant status
5.1
9.6
20
40
Z01.2
ICD-10 Finland
Dental examination
1.5
9.6
543
4288
L21.0
ICD-10 Finland
Seborrhoea capitis
11.5
9.6
17
15
A10AE04
ATC
insulin glargine; parenteral
1.9
9.5
124
684
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.8
9.5
149
871
N03AX16
ATC
[U] pregabalin
1.6
9.5
284
1966
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
3.3
9.5
35
108
I50.9
ICD-10 Finland
Heart failure, unspecified
1.8
9.4
150
881
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.5
9.4
297
2083
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.8
9.4
156
929
A10AD01
ATC
insulin (human); parenteral
3.8
9.4
28
75
B86
ICD-10 Finland
Scabies
3.4
9.3
33
99
D64.9
ICD-10 Finland
Anaemia, unspecified
1.9
9.3
122
674
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.5
9.3
60
251
R52.9
ICD-10 Finland
Pain, unspecified
1.9
9.3
120
661
K13.74
ICD-10 Finland
Lichen rubs planus in the mouth
3.9
9.3
27
71
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
9.2
206
1328
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.8
9.2
133
758
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.9
9.2
109
583
R11
ICD-10 Finland
Nausea and vomiting
2.0
9.1
104
548
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
9.1
216
1413
PHD99
NOMESCO Finland
Resection of other vein
2.1
9.1
85
416
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
3.2
9.1
35
111
D07AC03
ATC
desoximetasone; topical
3.8
9.1
27
72
127
Kela drug reimbursment
Transplant complication
4.0
9.1
25
63
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
9.1
348
2541
C03DA01
ATC
spironolactone; oral
1.8
9.0
140
816
EBA00
NOMESCO Finland
Extraction of tooth
1.5
9.0
433
3304
D06AX01
ATC
fusidic acid; topical
1.9
9.0
115
631
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.2
9.0
73
339
AA1AD
NOMESCO Finland
CT of head and brain
1.5
9.0
324
2336
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
8.9
282
1974
R03BA01
ATC
beclometasone; inhalant
1.7
8.9
165
1012
R03DC03
ATC
montelukast; oral
1.7
8.9
194
1244
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.0
8.9
103
547
D07AB01
ATC
clobetasone; topical
2.9
8.9
41
145
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
8.8
885
7707
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
8.8
94
485
M13.9
ICD-10 Finland
Arthritis, unspecified
2.0
8.8
93
478
SFA30
NOMESCO Finland
Three-surface restoration
1.4
8.8
530
4216
L23.5
ICD-10 Finland
Allergic contact dermatitis due to other chemical products
50.3
8.7
10
*
D11AH05
ATC
dupilumab; topical
50.3
8.7
10
*
L40
ICD-10 Finland
Psoriasis
3.2
8.7
33
104
0350X
ICD-9 Finland
Erysipelas[ERYSIPELAS ALIA DEFINITA SEU NUD]
7.7
8.7
19
25
L04AA01
ATC
[U] ciclosporin
4.4
8.6
21
48
R06AX22
ATC
ebastine; oral
1.6
8.6
197
1278
L29.0
ICD-10 Finland
Pruritus ani
9.0
8.5
17
19
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
8.5
261
1814
L24.9
ICD-10 Finland
Irritant contact dermatitis, unspecified cause
27.7
8.5
11
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.9
8.5
111
614
L73.8
ICD-10 Finland
Other specified follicular disorders
7.4
8.5
19
26
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.1
8.5
83
415
EKA10
NOMESCO Finland
iopsy of buccal mucosa
3.2
8.4
33
106
A10AC01
ATC
insulin (human); parenteral
2.0
8.4
94
493
F41.09
ICD-10 Finland
UNS Panic Syndrome
3.0
8.4
36
122
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.9
8.4
108
594
J01CE02
ATC
phenoxymethylpenicillin; oral
1.4
8.4
837
7248
I50.0
ICD-10 Finland
Congestive heart failure
2.1
8.4
82
410
6929X
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[DERMATITITIS ARTEFACTA NUD]
+∞
8.3
8
*
L26
ICD-10 Finland
Exfoliative dermatitis
+∞
8.3
8
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.2
8.3
66
303
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.7
8.3
147
891
EB1VA, ,
NOMESCO Finland
1.7
8.3
153
938
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.8
8.3
136
807
A10BA02
ATC
metformin; oral
1.5
8.2
337
2486
K07
ICPC
Swollen ankles/oedema
2.3
8.2
58
254
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
8.2
572
4653
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.3
8.1
62
280
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
8.1
362
2715
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
2.4
8.1
54
230
L04AX01
ATC
azathioprine; systemic
2.4
8.1
53
224
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.1
8.1
22
55
A10AB04
ATC
insulin lispro; parenteral
2.6
8.1
44
170
A41.9
ICD-10 Finland
Sepsis, unspecified
2.6
8.1
46
182
I80.0
ICD-10 Finland
Phlebitis and thrombophlebitis of superficial vessels of lower extremities
2.5
8.1
49
200
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
8.0
172
1097
SFA40
NOMESCO Finland
Restoration involving the entire crown of the tooth
1.5
8.0
278
1982
M03BX02
ATC
tizanidine; oral
1.4
8.0
770
6601
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
8.0
667
5584
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
8.0
192
1261
SPAT1151
SPAT
Treatment of major wounds
4.3
8.0
20
47
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.8
7.9
112
635
SPAT1310
SPAT
Counselling related to known health issue
1.5
7.9
360
2708
SPAT1097
SPAT
Recording of ECG
1.6
7.9
175
1126
N18.8
ICD-10 Finland
Other chronic renal failure
3.2
7.9
31
100
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.2
7.8
61
279
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.6
7.8
173
1113
D07XB01
ATC
flumetasone; topical
9.5
7.8
15
16
J46
ICD-10 Finland
Status asthmaticus
2.9
7.8
35
122
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
1.8
7.8
113
646
N06AA09
ATC
amitriptyline; systemic
1.8
7.8
116
669
TGC00
NOMESCO Finland
Bronchial lavation
3.0
7.7
34
117
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
6.4
7.7
19
30
PH2DE
NOMESCO Finland
Ultrasound examination of bloodflow in veins of lower extremity with Doppler method
2.7
7.7
40
151
L03
ICPC
Low back symptom/complaint
1.5
7.6
318
2350
L14
ICPC
Leg/thigh symptom/complaint
1.9
7.6
97
532
L23.3
ICD-10 Finland
Allergic contact dermatitis due to drugs in contact with skin
18.5
7.6
11
6
B07.9
ICD-10 Finland
Verruca simplex
2.6
7.6
43
170
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.9
7.5
94
513
KMAK, ,
NOMESCO Finland
1.4
7.5
614
5105
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
7.5
130
784
WXQ10
NOMESCO Finland
Psoralen - Ultraviolet A therapy with systemic sensitivisation
80.5
7.4
8
*
T78.4
ICD-10 Finland
Allergy, unspecified
2.4
7.4
48
202
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
7.4
124
740
SFA10
NOMESCO Finland
One-surface restoration
1.4
7.4
656
5519
A03
ICPC
Fever
1.6
7.4
182
1202
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.4
7.3
47
197
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.3
7.3
51
222
S19
ICPC
Skin injury other
2.3
7.3
51
222
L16
ICPC
Ankle symptom/complaint
1.7
7.3
131
796
6918B
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[ECZEMA ATOPICUM]
+∞
7.3
7
*
L24.0
ICD-10 Finland
Irritant contact dermatitis due to detergents
+∞
7.3
7
*
J04BA02
ATC
dapsone; oral
9.4
7.3
14
15
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.9
7.3
93
511
N05CF01
ATC
zopiclone; oral
1.4
7.3
366
2799
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
2.6
7.2
39
150
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.4
7.2
46
192
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
7.3
7.2
16
22
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.9
7.2
85
455
SPAT1193
SPAT
Pap smear
1.9
7.2
93
513
L15
ICPC
Knee symptom/complaint
1.5
7.2
276
2006
SFA20
NOMESCO Finland
Two-surface restoration
1.4
7.2
708
6047
K13.78
ICD-10 Finland
Other change in the oral mucosa
3.0
7.1
31
106
SPAT1255
SPAT
Intravenous administration of medicine
2.0
7.1
79
413
J01MA12
ATC
levofloxacin; systemic
1.5
7.1
213
1468
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.8
7.1
101
573
A02BC01
ATC
omeprazole; systemic
1.4
7.1
313
2333
N30.0
ICD-10 Finland
Acute cystitis
1.6
7.1
170
1113
A02BC05
ATC
esomeprazole; systemic
1.4
7.1
482
3875
L04AA13
ATC
[U] leflunomide
2.8
7.1
34
123
N03AX12
ATC
[U] gabapentin; oral
1.6
7.1
193
1304
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
2.6
7.1
40
158
J01EA01
ATC
trimethoprim; systemic
1.5
7.1
282
2064
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
2.9
7.0
31
107
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
7.0
377
2912
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
7.0
431
3408
L04AA06
ATC
mycophenolic acid; systemic
3.3
7.0
25
76
H57.1
ICD-10 Finland
Ocular pain
2.4
7.0
47
202
L40.8
ICD-10 Finland
Other psoriasis
6.4
6.9
17
27
M54.5
ICD-10 Finland
Low back pain
1.4
6.9
417
3283
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.5
6.9
251
1801
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
5.9
6.9
18
31
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.9
6.9
84
454
D01
ICPC
Abdominal pain/cramps general
1.7
6.9
131
809
L50.0
ICD-10 Finland
Allergic urticaria
3.0
6.9
30
103
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.0
6.8
71
363
C07AB07
ATC
bisoprolol; oral
1.4
6.8
562
4652
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.4
6.8
44
185
P01BA02
ATC
hydroxychloroquine; oral
1.8
6.8
96
544
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.6
6.8
142
900
WZC00, ,
SPAT
1.7
6.7
113
674
L30.1
ICD-10 Finland
Dyshidrosis [pompholyx]
16.8
6.7
10
6
E66.9
ICD-10 Finland
Obesity, unspecified
2.4
6.7
46
199
S88
ICPC
Dermatitis contact/allergic
3.4
6.7
23
68
N06AB03
ATC
fluoxetine; oral
1.6
6.7
145
927
L98.1
ICD-10 Finland
Factitial dermatitis
22.6
6.7
9
*
K90.0
ICD-10 Finland
Coeliac disease
2.6
6.7
36
139
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.0
6.7
74
388
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
6.7
329
2502
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.5
6.6
39
157
H01
ICPC
Ear pain/earache
1.7
6.6
119
724
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
3.6
6.6
21
59
H03AA01
ATC
levothyroxine sodium; systemic
1.5
6.6
266
1948
A10AB01
ATC
insulin (human); parenteral
2.4
6.6
43
182
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
6.6
720
6212
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
3.5
6.6
22
64
M25.5
ICD-10 Finland
Pain in joint
1.4
6.6
371
2886
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.5
6.6
38
152
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.7
6.5
33
123
SPAT1284
SPAT
Extensive health certificate
2.6
6.5
35
135
A07AA02
ATC
nystatin; oral
2.0
6.5
65
329
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
6.5
239
1721
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.4
6.5
330
2523
J02AC02
ATC
itraconazole; systemic
1.5
6.4
197
1364
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
6.4
202
1407
R01AD58
ATC
fluticasone, combinations; nasal
1.5
6.4
262
1923
R10.2
ICD-10 Finland
Pelvic and perineal pain
2.9
6.4
29
102
M04AA01
ATC
allopurinol; systemic
1.6
6.4
143
922
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.9
6.4
78
423
SGA02
NOMESCO Finland
Opening and preparing the root canals
1.6
6.4
150
979
UKC02
NOMESCO Finland
Cystoscopy
1.6
6.3
174
1176
5613
FHL
Conjunctival occlusion
8.2
6.3
13
16
45499
ICD-8 Finland
Varicose veins of lower extremities, Other and unspecified, without ulcer
2.1
6.3
60
297
S91
ICPC
Psoriasis
5.5
6.3
17
31
M79.1
ICD-10 Finland
Myalgia
1.6
6.3
164
1097
69299
ICD-8 Finland
Other eczema and dermatitis, Due to other and unspecified cause
+∞
6.3
6
*
69798
ICD-8 Finland
Lichen, Alius definitus
+∞
6.3
6
*
6983A
ICD-9 Finland
Pruritus and related conditions, Lichenification and lichen simplex chronicus[PRURIGO NODULARIS HYDE]
+∞
6.3
6
*
L50.9
ICD-10 Finland
Urticaria, unspecified
2.4
6.2
40
168
J33.0
ICD-10 Finland
Polyp of nasal cavity
2.5
6.2
37
150
R03BB04
ATC
tiotropium bromide; inhalant
1.7
6.2
117
721
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
5.1
6.2
18
36
WW200
NOMESCO Finland
Immunization
2.6
6.2
34
133
PHM76
NOMESCO Finland
Endovenous obliteration of v.saphena magna
2.2
6.1
51
240
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
3.0
6.1
26
88
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
1.6
6.1
144
940
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
6.1
270
2010
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.8
6.1
94
548
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
2.5
6.1
36
146
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
6.1
109
664
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
6.0
121
758
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
6.1
6.0
15
25

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
207
343
6.96
123.06
1.3
1.2
—
—
—
0
0
770
5243
2.12
38.10
7.3
5.7
0.04
0.04
e9/l
3.90
720
4545
768
5238
2.11
37.66
7.3
5.7
0.59
0.58
e9/l
1.22
717
4539
788
5440
2.10
37.23
7.5
5.9
0.24
0.19
e9/l
8.30
741
4788
780
5381
2.09
36.71
7.4
5.7
1.83
1.95
e9/l
1.18
733
4775
729
4935
2.06
35.77
7.9
6.2
—
—
—
0
0
252
1140
2.49
33.76
2.1
1.6
—
—
—
0
0
155
548
3.07
33.41
1.5
1.2
387.08
165.68
u/ml
1.31
142
498
258
1191
2.45
33.03
1.6
1.4
—
—
—
0
0
696
4947
1.86
26.40
7.7
5.9
3.34
2.83
%
5.22
672
4628
698
4971
1.85
26.26
8.0
6.2
8.39
8.62
%
1.28
675
4659
818
6123
1.87
26.22
10.6
9.0
4.25
4.09
e9/l
1.35
763
5381
709
5101
1.84
25.54
7.8
6.0
26.42
27.96
%
3.65
685
4788
675
4795
1.83
25.24
7.7
5.9
0.68
0.67
%
0.34
653
4478
699
5020
1.83
25.21
7.5
5.7
58.08
57.18
%
1.27
677
4715
512
3355
1.86
24.76
3.3
2.5
56.83
81.91
u/l
0.53
481
3104
446
2806
1.89
24.46
5.2
4.2
—
—
—
0
0
991
7987
1.95
24.19
5.3
3.9
14.45
11.76
mm/h
6.19
941
7386
492
3225
1.83
23.48
2.3
2.2
184.06
218.87
u/l
0.37
465
3041
262
1391
2.10
23.28
1.5
1.3
630.32
491.11
titre
0.40
62
288
1016
8367
1.91
21.77
8.9
7.3
80.00
77.86
u/l
0.87
974
7875
331
1980
1.89
20.66
1.6
1.5
2.74
2.45
g/l
1.13
212
1220
811
6306
1.73
20.32
6.3
4.6
6.99
6.70
mmol/l
2.68
766
5934
360
2239
1.83
19.74
1.4
1.2
2.32
1.35
u/ml
0.66
98
606
621
4520
1.70
19.56
5.8
4.7
35.28
35.62
g/l
0.82
585
4232
261
1488
1.94
18.64
2.4
2.0
—
—
—
0
0
304
1828
1.86
18.41
1.3
1.3
38.40
33.92
iu/ml
0.25
100
604
456
3109
1.71
17.88
3.3
2.9
—
—
—
0
0
692
5264
1.66
17.82
9.7
6.5
1.21
1.21
mmol/l
0.74
597
4447
457
3125
1.71
17.69
3.5
3.2
589.32
199.17
mg/l
0.90
318
1972
476
3300
1.69
17.45
4.1
3.7
13.74
7.64
mg/mmol
1.11
339
2057
385
2531
1.73
17.09
2.5
2.1
2.93
2.98
mg/l
0.15
342
2138
169
892
2.03
14.87
10.2
7.0
10.71
9.55
mmol/l
1.22
160
853
233
1373
1.85
14.76
8.9
5.4
1.10
1.03
mmol/l
2.73
225
1268
278
1729
1.77
14.71
1.3
1.2
11.20
12.95
u/ml
0.15
103
690
641
4934
1.58
14.62
15.8
13.6
1.24
1.24
inr
0.06
205
1464
711
5611
1.58
14.51
6.1
6.2
11.20
11.50
umol/l
0.14
689
5337
884
7340
1.61
14.50
5.4
4.1
—
—
—
0
0
200
1140
1.89
14.02
1.8
1.6
—
—
—
0
0
574
4348
1.56
13.78
2.6
2.2
72.27
77.08
nmol/l
4.68
532
3894
463
3339
1.59
13.75
3.5
3.1
7.58
7.67
mmol/l
0.17
403
2801
212
1244
1.84
13.54
2.3
2.3
134.46
125.06
ug/g
0.18
175
999
562
4260
1.55
13.32
2.2
1.9
94.66
95.51
pmol/l
0.16
318
2211
966
8305
1.60
12.65
4.6
3.9
14.79
14.77
pmol/l
0.08
912
7561
170
953
1.90
12.49
2.7
2.0
359.94
371.89
nmol/l
0.30
162
878
1194
10893
1.95
12.26
20.3
13.3
23.91
23.53
mg/l
0.14
1036
8562
612
4786
1.52
12.22
8.6
5.8
1.21
1.21
mmol/l
0.64
571
4352
661
5268
1.51
11.97
4.4
3.4
0.05
0.00
estimate
0.73
117
963
85
373
2.37
11.84
1.2
1.3
3.72
1.12
u/ml
—
6
31
655
5220
1.50
11.80
4.4
3.4
0.01
0.00
estimate
0.26
130
1054
166
940
1.88
11.80
5.9
3.5
1.29
2.05
mmol/l
1.91
144
768
830
6947
1.52
11.80
5.5
4.1
64.43
2382.10
e6/l
1.77
14
104
92
420
2.28
11.70
1.7
1.9
2.07
2.01
ug/l
0.02
81
371
572
4451
1.50
11.47
3.7
2.7
114.84
137.85
ug/l
2.50
530
4108
148
824
1.90
11.07
2.8
2.8
152.79
191.03
ng/l
0.59
134
753
249
1614
1.67
11.06
3.7
2.4
12.34
13.29
umol/l
1.40
233
1504
93
437
2.21
11.04
4.4
5.1
1.74
1.58
%
0.66
85
410
648
5198
1.48
11.03
5.8
4.7
0.00
0.00
estimate
0.50
126
994
263
1732
1.65
10.98
3.2
3.3
0.80
0.82
mmol/l
0.89
243
1635
534
4127
1.49
10.91
3.8
3.4
36.82
47.50
ng/l
0.49
363
2859
540
4190
1.49
10.79
3.8
3.1
5.79
5.86
ph
0.14
29
319
181
1083
1.78
10.72
8.7
7.9
95.61
95.30
%
0.38
173
1043
407
2991
1.52
10.53
3.2
2.9
1934.14
1264.32
ng/l
1.34
357
2526
195
1200
1.73
10.47
8.3
7.5
5.06
5.14
kpa
0.67
185
1153
231
1489
1.67
10.44
3.7
2.4
2.33
2.32
g/l
0.06
219
1374
218
1384
1.69
10.44
3.8
2.4
20.89
23.75
%
2.52
180
1184
195
1201
1.73
10.44
8.3
7.5
11.78
12.26
kpa
0.50
185
1153
328
2304
1.56
10.41
4.5
3.7
1.02
1.02
kg/l
0.12
57
338
195
1203
1.73
10.37
8.4
7.5
0.98
1.09
mmol/l
0.14
146
958
147
838
1.85
10.20
2.8
3.0
67.06
66.63
g/l
0.33
137
763
126
686
1.92
10.07
2.5
2.7
—
—
—
0
0
278
1895
1.59
10.00
1.8
1.7
1186.07
1222.77
nmol/l
0.27
235
1414
216
1386
1.67
9.91
1.7
1.6
—
—
—
0
0
383
2809
1.51
9.89
2.9
2.5
3130.22
5778.11
umol/l
0.82
347
2474
139
788
1.85
9.81
3.1
2.7
11.16
10.52
g/l
0.81
127
725
180
1103
1.73
9.79
2.7
2.7
1.70
1.82
%
1.00
162
989
383
2816
1.51
9.75
4.9
3.7
0.00
0.01
estimate
1.08
118
964
42
144
2.98
9.56
1.0
1.1
7.24
5.02
u/ml
0.18
19
67
462
3541
1.47
9.52
3.4
3.3
30.89
33.01
u/l
0.83
443
3359
137
781
1.84
9.50
5.0
3.7
103.42
83.17
ng/l
1.38
120
691
1214
11291
1.88
9.49
22.4
15.2
139.49
139.72
mmol/l
2.50
1190
10992
64
274
2.40
9.45
2.0
2.2
10.83
11.15
mg/l
0.11
59
255
307
2171
1.54
9.33
3.1
2.4
5.11
5.93
e6/l
0.46
287
1958
88
434
2.10
9.27
4.6
5.1
0.87
0.90
%
0.26
81
408
1216
11330
1.87
9.24
22.4
15.3
4.00
3.97
mmol/l
2.93
1190
11013
131
743
1.85
9.23
1.5
1.4
—
—
—
0
0
32
95
3.43
9.21
1.4
1.3
30350.36
120773.89
e6/l
0.65
25
65
1101
9997
1.59
9.16
5.6
4.6
1.96
2.20
mu/l
0.52
1037
9162
123
686
1.87
9.14
5.7
4.8
—
—
—
0
0
59
249
2.43
9.00
1.8
1.6
15449.24
13858.53
e6/l
0.11
45
187
135
785
1.80
8.77
1.3
1.2
—
—
—
0
0
241
1635
1.58
8.75
1.9
1.7
—
—
—
0
0
40
142
2.87
8.59
1.1
1.1
0.33
1.80
u/ml
0.90
16
54
118
665
1.85
8.49
9.2
6.9
24.48
24.60
mmol/l
0.11
110
630
140
831
1.77
8.49
2.9
2.8
67.57
71.88
e9/l
0.97
114
629
43
161
2.73
8.37
1.1
1.1
4.86
2.09
u/ml
0.30
23
77
18
37
4.92
8.37
1.1
1.0
0.48
2.66
u/ml
—
7
10
146
883
1.73
8.29
4.8
4.1
0.62
1.11
%
2.10
64
307
45
176
2.61
8.06
1.2
1.3
—
—
—
0
0
106
592
1.86
7.85
1.3
1.2
—
—
—
0
0
401
3082
1.43
7.83
5.9
4.0
7.39
7.40
ph
0.87
83
626
139
846
1.72
7.72
4.2
3.1
—
—
—
0
0
159
1006
1.66
7.64
9.6
8.1
121.09
122.27
g/l
0.29
152
978
1104
10138
1.53
7.59
7.0
5.6
41.38
39.84
mmol/mol
5.06
1036
9418
108
618
1.81
7.41
2.2
1.8
1.17
1.40
g/l
0.64
98
571
326
2448
1.44
7.13
1.7
1.5
20.45
20.95
nmol/l
0.22
286
2074
48
206
2.38
7.11
1.7
1.4
—
—
—
0
0
26
82
3.21
6.86
1.2
1.3
7.86
7.27
g/l
0.23
21
58
450
3596
1.38
6.83
3.3
3.4
2.35
2.35
mmol/l
0.60
409
3177
134
835
1.67
6.82
5.0
4.2
0.10
0.11
%
0.11
52
259
304
2272
1.44
6.78
1.7
1.7
418.83
37586818.26
pmol/l
2.45
261
1881
129
797
1.69
6.78
4.8
3.9
0.65
0.77
%
0.33
54
265
14
18
7.85
6.62
1.1
1.0
0.64
0.08
u/ml
—
6
8
601
5056
1.34
6.46
2.9
2.5
—
—
—
0
0
57
275
2.12
6.43
1.1
1.1
11.04
4.10
u/ml
—
7
35
400
3163
1.38
6.39
3.9
3.1
46.86
86.69
e6/l
0.81
339
2428
372
2907
1.39
6.39
3.9
3.2
—
—
—
0
0
97
565
1.77
6.30
10.5
10.0
—
—
—
0
0
23
71
3.28
6.29
1.2
1.1
—
88.84
—
0
5
151
991
1.59
6.25
2.3
2.1
0.22
0.21
g/l
0.24
141
933
25
82
3.09
6.21
1.2
1.3
0.43
0.41
g/l
0.11
20
58
25
82
3.09
6.21
1.2
1.3
3.22
3.08
g/l
0.14
20
58
60
302
2.03
6.07
1.6
1.4
313.31
287.62
ug/g
0.38
35
169
65
337
1.98
6.06
6.2
6.2
1.43
1.35
mmol/l
0.27
55
294
454
3691
1.35
6.01
4.4
3.5
101.66
100.67
e6/l
0.01
362
2599
1146
10728
1.50
5.96
5.3
4.4
6.20
5.95
mmol/l
4.60
1060
9803
310
2375
1.40
5.93
1.7
1.6
1.22
1.14
mg/l
0.22
245
1830
562
4727
1.33
5.87
11.8
9.3
0.00
0.00
e9/l
0.23
493
3897
25
85
2.98
5.86
1.2
1.3
—
—
—
0
0
117
734
1.65
5.82
3.3
2.9
8.47
4.54
e9/l
0.90
99
600
276
2085
1.41
5.71
3.6
2.8
531.22
550.76
mosm/kgh2o
0.76
250
1805
270
2035
1.41
5.66
4.5
3.7
281.71
417.94
ng/l
0.42
194
1566
28
104
2.73
5.62
1.4
1.2
—
—
—
0
0
31
122
2.58
5.56
1.9
1.6
57.70
59.35
%
0.07
20
77
50
245
2.08
5.46
1.3
1.2
1.84
2.39
u/ml
—
5
26
42
192
2.23
5.45
1.8
1.5
122.28
142.91
u/ml
0.39
16
34
47
225
2.13
5.45
4.1
4.5
—
—
—
0
0
50
247
2.06
5.35
6.2
6.8
11.84
11.28
mmol/l
0.52
43
223
50
247
2.06
5.35
6.2
6.8
104.51
105.58
mmol/l
0.79
43
223
1163
10967
1.49
5.34
5.2
4.4
4.63
4.70
mmol/l
1.61
1095
10215
1157
10904
1.47
5.28
5.0
4.3
1.38
1.46
mmol/l
11.03
1088
10079
305
2372
1.37
5.27
4.2
3.3
—
—
—
0
0
32
132
2.46
5.23
1.1
1.1
1.99
0.80
u/ml
0.46
17
57
20
65
3.11
5.08
1.7
1.7
—
—
—
0
0
122
801
1.58
5.06
5.3
4.2
0.53
0.15
%
0.33
40
227
34
148
2.33
4.96
1.3
1.7
0.87
0.86
g/l
0.02
28
114
54
288
1.91
4.70
1.3
1.2
112.00
92.61
titre
—
5
23
817
7359
1.29
4.66
3.7
3.1
48.30
49.68
u/l
0.21
766
6890
22
80
2.78
4.62
2.3
2.1
9.95
4.55
umol/l
0.55
17
52
28
116
2.44
4.57
1.1
1.0
3.78
1.62
u/ml
0.31
15
46
19
64
3.00
4.56
1.2
1.1
—
—
—
0
0
166
1192
1.45
4.51
1.4
1.3
—
—
—
0
0
248
1911
1.37
4.49
2.5
3.0
2.44
2.45
mmol/l
0.38
220
1691
26
105
2.51
4.48
1.0
1.1
7.38
3.08
u/ml
0.42
11
32
23
88
2.64
4.41
1.7
1.4
16.75
31.66
%
1.30
13
56
61
346
1.80
4.40
2.7
2.8
10.75
10.34
g/l
0.35
55
313
67
391
1.75
4.40
3.2
3.4
0.16
0.27
g/l
1.51
29
160
330
2664
1.32
4.36
7.2
6.7
—
—
—
0
0
24
95
2.55
4.31
1.1
1.0
0.04
0.06
u/ml
—
8
24
1173
11167
1.43
4.25
5.6
4.8
2.75
2.79
mmol/l
0.87
1103
10330
43
220
1.99
4.24
2.0
2.4
16.54
16.25
%
0.11
21
113
129
893
1.49
4.23
2.3
2.4
4.57
7.39
ug/l
2.66
113
795
36
173
2.11
4.20
1.1
1.0
—
—
—
0
0
1117
10552
1.37
4.19
4.6
3.9
1.46
1.31
mmol/l
7.78
1042
9688
42
215
1.98
4.14
1.8
1.7
—
—
—
0
0
198
1491
1.39
4.12
1.3
1.2
—
—
—
0
0
8
10
8.04
4.06
1.0
1.0
—
—
—
0
0
39
196
2.02
4.05
2.0
1.5
—
—
—
0
0
350
2876
1.29
4.02
3.9
3.0
0.42
0.50
e6/l
0.18
296
2178
54
304
1.81
4.02
4.0
4.3
47.92
68.48
mg/l
0.47
41
249
54
304
1.81
4.02
3.9
4.3
46.61
38.64
mg/l
0.30
42
248
110
745
1.52
4.01
1.5
1.5
—
—
—
0
0
43
225
1.94
4.00
6.6
2.7
—
—
—
0
0
850
7764
1.26
3.99
4.1
3.7
—
—
—
0
0
34
164
2.10
3.94
1.4
1.3
56.44
65.30
mmol/l
0.80
27
138
147
1059
1.44
3.94
1.5
1.4
—
—
—
0
0
14
37
3.81
3.89
1.5
1.5
—
—
—
0
0
340
2794
1.29
3.89
3.8
2.9
—
—
—
0
0
23
95
2.45
3.81
1.6
1.6
—
—
—
0
0
48
266
1.83
3.77
3.8
4.7
—
—
—
0
0
6
5
12.05
3.76
1.2
1.4
—
—
—
0
0
25
109
2.32
3.70
3.2
4.4
—
—
—
0
0
147
1076
1.41
3.62
5.2
4.0
—
—
—
0
0
102
696
1.50
3.61
4.2
3.5
5.20
5.17
kpa
0.14
95
671
121
855
1.46
3.60
12.4
8.5
—
—
—
0
0
33
164
2.04
3.57
1.8
1.5
—
—
—
0
0
25
111
2.28
3.56
1.2
1.5
—
—
—
0
0
35
178
1.99
3.55
1.3
1.2
—
—
—
0
0
41
222
1.87
3.48
1.7
2.2
131.97
131.88
g/l
0.01
30
168
100
686
1.50
3.46
4.2
3.5
7.40
7.40
ph
0.05
15
86
39
211
1.87
3.33
5.1
3.5
4.20
4.10
e9/l
0.10
39
211
102
709
1.48
3.32
1.1
1.2
108.30
146.51
iu/ml
0.55
42
274
69
440
1.60
3.31
1.9
1.9
1.80
1.53
g/l
1.66
56
389
1217
11743
1.44
3.31
13.5
10.0
26.55
26.80
u/l
0.22
1180
11370
14
48
2.94
3.30
1.8
3.0
1126.57
805.40
u/ml
0.45
14
48
26
122
2.15
3.27
1.2
1.1
—
—
—
0
0
41
227
1.83
3.27
4.0
3.5
—
—
—
0
0
372
3149
1.25
3.27
3.9
3.7
—
—
—
0
0
1008
9482
1.26
3.24
22.0
15.9
15.25
14.94
%
0.84
999
9302
33
172
1.94
3.16
5.1
2.9
—
—
—
0
0
36
194
1.88
3.13
3.0
2.7
—
—
—
0
0
59
371
1.62
3.02
1.1
1.1
—
—
—
0
0
7
12
5.86
3.02
13.6
3.6
5.47
6.38
mmol/l
—
7
12
40
228
1.78
2.93
2.7
2.9
1.53
1.56
mmol/l
0.08
40
222
19
82
2.34
2.92
1.4
1.1
—
—
—
0
0
39
221
1.79
2.92
5.9
3.8
58.54
56.51
%
0.44
39
221
90
629
1.46
2.88
2.7
3.4
4.47
4.55
pmol/l
0.32
81
556
1190
11483
1.35
2.83
19.1
12.6
—
—
—
0
0
11
33
3.35
2.81
7.4
5.5
—
—
—
0
0
18
78
2.33
2.75
1.1
1.2
—
—
—
0
0
37
211
1.78
2.73
2.8
3.0
7.27
7.62
mmol/l
0.39
37
206
483
4268
1.21
2.73
2.1
2.1
—
—
—
0
0
15
60
2.52
2.70
1.1
1.2
136.73
145.42
nmol/l
0.22
15
60
10
29
3.47
2.69
1.1
1.0
—
—
—
0
0
152
1178
1.33
2.66
2.3
2.8
7.14
8.39
umol/l
0.39
131
1033
39
228
1.73
2.65
4.2
4.1
2.42
2.45
mmol/l
0.02
26
155
214
1740
1.27
2.61
3.0
2.6
0.65
1.06
e6/l
3.98
133
979
10
30
3.35
2.60
1.5
1.4
—
—
—
0
0
41
245
1.69
2.59
2.9
2.9
8.09
8.16
kpa
0.11
41
239
22
107
2.07
2.58
1.5
1.4
33395.47
96264.41
e6/l
0.49
15
59
39
231
1.71
2.54
1.5
1.3
24.07
23.92
e6/l
0.00
30
184
39
231
1.71
2.54
1.5
1.3
7682.75
956.65
e6/l
0.52
32
189
13
50
2.62
2.53
1.3
1.3
172.56
173.59
mmol/24h
0.01
13
50
22
109
2.04
2.47
2.1
2.6
0.88
1.37
g/24h
0.80
16
52
9
224
0.40
2.43
1.4
1.7
—
—
—
0
0
5
8
6.27
2.37
1.4
1.1
—
—
—
0
0
77
1066
0.71
2.33
1.2
1.4
—
—
—
0
0
9
28
3.23
2.31
1.0
1.4
—
—
—
0
0
99
738
1.37
2.26
1.8
1.6
—
—
—
0
0
46
296
1.57
2.21
2.4
2.8
36.89
37.85
g/l
0.63
40
263
64
444
1.46
2.19
1.4
1.3
30.82
30.69
iu/l
0.01
58
382
30
173
1.75
2.18
1.1
1.1
—
—
—
0
0
35
213
1.66
2.11
1.6
1.3
—
—
—
0
0
53
357
1.50
2.10
1.8
1.6
—
—
—
0
0
364
4111
0.84
2.08
3.3
2.8
—
—
—
0
0
18
89
2.04
2.06
4.1
2.0
9.87
10.80
%
0.38
18
89
7
20
3.51
2.05
1.1
1.4
—
—
—
0
0
22
118
1.88
2.02
1.5
1.4
270.41
280.61
mosm/kgh2o
1.01
17
94
47
312
1.52
2.00
1.5
1.2
—
—
—
0
0
1252
12255
1.38
2.00
30.1
19.6
39.82
40.27
%
1.38
1140
11471
92
693
1.35
1.99
3.2
2.7
—
—
—
0
0
13
57
2.29
1.98
1.1
1.0
—
—
—
0
0
21
112
1.89
1.97
1.0
1.2
—
—
—
0
0
7
21
3.35
1.96
2.0
1.9
—
—
—
0
0
1252
12261
1.37
1.93
30.0
19.5
254.87
250.29
e9/l
1.54
1233
11960
115
901
1.30
1.91
5.6
3.5
1.22
1.23
mmol/l
0.82
104
781
147
1190
1.26
1.89
1.5
1.6
—
—
—
0
0
28
166
1.70
1.88
1.7
2.6
—
—
—
0
0
1252
12267
1.36
1.86
29.8
19.5
91.04
91.00
fl
0.13
1242
12097
1252
12268
1.36
1.85
29.9
19.5
6.95
6.64
e9/l
6.15
1231
11931
1252
12268
1.36
1.85
29.7
19.4
30.27
30.32
pg
0.46
1241
12096
1252
12269
1.36
1.84
29.9
19.5
4.48
4.51
e12/l
1.42
1231
11929
5
12
4.18
1.82
1.6
1.5
66.54
95.50
ng/l
—
5
12
5
12
4.18
1.82
1.4
1.1
—
—
—
0
0
335
2957
1.18
1.82
1.9
1.6
1.48
1.38
mmol/l
1.27
292
2474
32
199
1.62
1.81
1.6
1.2
290.68
255.38
u/ml
0.24
19
119
1252
12274
1.35
1.79
30.0
19.6
134.79
136.15
g/l
2.45
1242
12098
25
146
1.73
1.78
2.7
2.1
—
—
—
0
0
57
405
1.43
1.77
6.5
4.6
—
—
—
0
0
90
691
1.32
1.75
1.4
1.3
—
—
—
0
0
179
2119
0.82
1.70
2.6
3.0
0.65
0.76
ug/l
1.08
109
1363
24
142
1.70
1.65
1.1
1.0
3.26
2.21
u/ml
—
8
64
7
25
2.81
1.65
1.0
1.2
—
—
—
0
0
10
42
2.39
1.62
1.1
1.1
1612.30
1546.95
miu/ml
—
10
42
22
128
1.73
1.61
2.1
2.5
—
—
—
0
0
19
106
1.80
1.59
1.6
2.3
—
—
—
0
0
24
144
1.68
1.58
1.2
1.2
—
—
—
0
0
38
256
1.50
1.56
1.7
1.9
2.63
5.08
iu/l
1.66
16
88
289
2552
1.17
1.55
2.9
2.4
—
—
—
0
0
19
107
1.79
1.55
1.5
1.3
5.38
6.71
mmol/l
1.43
19
100
8
33
2.43
1.54
1.0
1.5
—
—
—
0
0
26
162
1.62
1.50
1.5
1.2
3.14
6.52
u/ml
0.90
14
66
12
58
2.08
1.49
1.8
2.9
2125.33
1945.30
ml
0.35
12
50
13
65
2.01
1.49
2.5
2.9
—
—
—
0
0
9
37
2.44
1.48
1.0
1.2
—
—
—
0
0
9
37
2.44
1.48
1.0
1.0
—
—
—
0
0
44
312
1.42
1.42
1.2
1.3
210.28
220.20
miu/ml
0.05
13
144
12
225
0.53
1.41
1.5
1.2
—
—
—
0
0
7
29
2.42
1.39
1.3
1.6
—
—
—
0
0
9
42
2.15
1.33
1.3
1.3
75.67
55.68
%
—
9
31
34
233
1.47
1.32
3.0
3.2
25.21
24.35
mg/l
0.05
20
147
17
98
1.74
1.31
1.5
1.4
—
—
—
0
0
19
114
1.68
1.28
1.4
1.2
—
—
—
0
0
191
1659
1.18
1.27
3.2
2.8
1.75
2.43
e6/l
0.82
110
904
6
25
2.41
1.24
1.8
1.5
46.67
31.21
%
—
6
14
65
505
1.30
1.23
5.1
3.6
—
—
—
0
0
5
19
2.64
1.21
7.6
6.3
—
—
—
0
0
42
307
1.38
1.18
1.4
1.2
—
—
—
0
0
369
3378
1.13
1.18
2.7
2.4
—
—
—
0
0
66
518
1.29
1.17
3.5
3.5
—
—
—
0
0
53
687
0.76
1.15
1.5
1.4
—
—
—
0
0
38
275
1.39
1.14
2.6
2.3
56.84
99.68
ug/min
0.66
18
167
17
103
1.66
1.13
1.2
1.1
—
—
—
0
0
17
103
1.66
1.13
1.3
1.2
—
—
—
0
0
16
257
0.62
1.11
1.4
1.3
—
—
—
0
0
56
434
1.30
1.10
5.3
3.8
24.20
24.95
mmol/l
0.92
49
408
7
32
2.19
1.08
2.7
2.3
—
—
—
0
0
43
324
1.34
1.03
3.9
2.9
—
—
—
0
0
20
130
1.55
1.03
1.3
1.2
—
—
—
0
0
7
34
2.06
1.03
2.0
1.6
—
—
—
0
0
10
53
1.89
1.01
1.5
1.2
—
—
—
0
0
20
131
1.53
1.00
2.3
1.5
0.15
0.33
nmol/l
2.04
11
99
7
35
2.01
1.00
1.3
1.3
1.57
3.04
%
—
7
28
7
35
2.01
1.00
1.9
1.8
—
—
—
0
0
17
108
1.58
0.96
2.6
2.4
—
—
—
0
0
10
54
1.86
0.96
2.0
3.3
—
—
—
0
0
40
302
1.33
0.96
2.1
1.5
338.57
298.64
mu/l
0.22
35
278
16
101
1.59
0.93
1.6
1.4
—
—
—
0
0
6
27
2.23
0.93
10.7
5.7
—
—
—
0
0
96
810
1.20
0.93
2.3
2.1
13.05
12.89
nmol/l
0.07
90
722
113
968
1.18
0.93
2.9
2.2
34.07
40.56
u/l
0.47
98
822
13
78
1.67
0.91
1.0
1.4
—
—
—
0
0
15
94
1.60
0.90
1.1
1.1
—
—
—
0
0
11
63
1.75
0.90
1.7
1.2
—
—
—
0
0
6
29
2.07
0.89
1.0
1.6
42.83
81.17
nmol/24h
—
6
29
8
42
1.91
0.88
2.0
1.9
93.84
54.94
ug/l
—
8
42
46
581
0.78
0.87
1.8
1.7
—
—
—
0
0
293
2697
1.11
0.85
4.6
3.8
91.82
90.68
%
0.33
283
2635
24
170
1.42
0.85
1.3
1.7
—
—
—
0
0
13
80
1.63
0.84
1.5
1.1
—
—
—
0
0
8
137
0.58
0.83
1.1
1.4
—
—
—
0
0
8
141
0.56
0.83
1.0
1.4
—
—
—
0
0
0
24
0.00
0.79
0.0
6.0
—
—
—
0
0
0
24
0.00
0.79
0.0
3.0
—
—
—
0
0
8
136
0.59
0.73
1.0
1.4
—
—
—
0
0
9
56
1.61
0.72
1.0
1.0
—
—
—
0
0
21
151
1.40
0.71
1.2
1.2
—
—
—
0
0
5
26
1.93
0.70
1.2
1.2
—
—
—
0
0
18
126
1.43
0.70
2.1
1.9
—
—
—
0
0
7
119
0.59
0.68
1.1
1.1
—
—
—
0
0
32
253
1.27
0.61
2.3
2.0
21077.48
4527.87
u/l
0.60
11
101
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
14
198
0.70
0.60
3.5
3.7
18.14
31.36
u/ml
1.07
14
193
8
52
1.54
0.59
2.3
2.6
42075.00
38861.63
ug/l
—
8
52
62
529
1.18
0.59
2.7
2.3
—
—
—
0
0
15
106
1.42
0.57
4.3
2.6
—
—
—
0
0
6
35
1.72
0.57
1.2
1.1
16.50
30.08
%
—
6
29
104
927
1.13
0.57
5.3
3.7
—
—
—
0
0
15
107
1.41
0.55
1.4
1.3
—
—
—
0
0
19
142
1.34
0.54
2.9
2.8
—
—
—
0
0
6
38
1.58
0.54
1.8
1.9
—
—
—
0
0
26
204
1.28
0.54
1.3
1.3
—
—
—
0
0
23
178
1.30
0.53
1.4
1.4
—
—
—
0
0
9
62
1.45
0.53
1.1
1.0
—
—
—
0
0
13
91
1.43
0.53
1.0
1.0
286.62
282.71
mg/l
0.08
13
77
9
63
1.43
0.52
1.7
1.5
—
—
—
0
0
6
40
1.50
0.51
1.5
2.9
—
—
—
0
0
7
45
1.56
0.49
1.0
1.1
164.37
257.16
iu/ml
—
7
45
11
76
1.45
0.48
1.4
1.4
196.23
167.78
pmol/l
0.29
11
76
7
49
1.43
0.46
20.4
16.0
—
—
—
0
0
7
49
1.43
0.46
1.4
1.9
—
—
—
0
0
40
339
1.19
0.44
11.0
9.9
—
—
—
0
0
7
51
1.37
0.44
3.7
2.4
—
—
—
0
0
378
3622
1.06
0.43
4.5
4.7
2.20
2.71
ug/l
0.59
335
3242
5
31
1.62
0.43
1.6
1.2
2.96
3.60
mmol/l
—
5
25
8
57
1.41
0.42
1.1
1.4
—
—
—
0
0
6
95
0.63
0.42
1.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.4
—
—
—
0
0
35
297
1.18
0.39
1.1
1.1
—
—
—
0
0
9
66
1.37
0.38
5.3
2.8
—
—
—
0
0
5
36
1.39
0.38
1.2
1.1
—
—
—
0
0
46
404
1.14
0.35
2.5
2.8
—
—
—
0
0
6
43
1.40
0.35
3.5
3.2
—
—
—
0
0
52
467
1.12
0.30
1.7
1.8
—
—
—
0
0
7
56
1.25
0.29
2.4
2.0
8.43
10.16
mmol/l
—
7
56
102
952
1.08
0.28
1.4
1.4
—
—
—
0
0
12
95
1.27
0.26
1.0
1.2
—
—
—
0
0
11
86
1.28
0.26
2.0
1.9
1.50
2.43
u/field
—
6
35
29
254
1.14
0.25
1.2
1.1
—
—
—
0
0
10
78
1.28
0.24
1.7
1.4
83.00
80.92
umol/l
—
10
78
5
39
1.28
0.23
2.0
2.3
87.36
18.01
ug/l
—
5
33
7
92
0.76
0.22
1.0
1.5
1.05
1.01
g/l
—
7
92
17
144
1.18
0.22
1.4
1.3
—
—
nmol/l
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
99
940
1.06
0.19
1.4
1.4
—
—
—
0
0
13
109
1.19
0.18
2.2
1.6
—
—
—
0
0
24
268
0.89
0.17
2.4
2.3
—
—
—
0
0
145
1397
1.04
0.16
1.3
1.3
—
—
—
0
0
8
71
1.13
0.16
5.3
7.2
—
—
—
0
0
8
71
1.13
0.16
1.9
2.2
—
—
—
0
0
44
473
0.93
0.16
1.0
1.1
—
—
—
0
0
14
160
0.87
0.14
1.1
1.1
—
9.48
—
0
12
24
263
0.91
0.13
1.8
2.0
—
—
—
0
0
115
1111
1.04
0.12
3.0
4.1
4.44
26.28
ug/l
2.06
99
919
31
332
0.93
0.11
1.6
2.0
—
—
—
0
0
6
57
1.05
0.08
1.0
1.3
—
—
—
0
0
29
308
0.94
0.08
1.7
2.0
—
—
—
0
0
10
113
0.88
0.08
1.9
1.9
—
—
—
0
0
5
62
0.81
0.08
1.0
1.1
—
—
—
0
0
31
328
0.94
0.08
1.6
1.8
—
—
—
0
0
10
88
1.14
0.08
1.4
1.1
290.00
165.71
titre
—
5
14
32
335
0.95
0.06
1.6
2.0
—
—
—
0
0
32
335
0.95
0.06
1.6
2.0
—
—
—
0
0
13
119
1.09
0.06
3.2
2.5
—
—
—
0
0
24
230
1.04
0.03
1.9
2.7
—
—
—
0
0
11
117
0.94
0.01
1.2
1.4
—
—
—
0
0
296
2972
0.99
0.01
1.4
1.4
—
—
—
0
0
14
147
0.95
0.01
1.4
1.4
—
—
—
0
0
17
166
1.02
0.00
1.2
1.1
—
—
—
0
0
15
148
1.01
0.00
2.0
2.5
—
—
—
0
0
17
167
1.02
0.00
1.2
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
180.13
—
0
8
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
1.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
6
62
0.97
-0.00
1.0
1.1
—
8.29
—
0
15
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
1.2
1.8
1.00
5.37
nmol/l
—
5
40
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
1.31
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
1.8
2.3
53.20
48.20
umol/l
—
5
42
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint L12_LICHENSIMPLEX and mortality.

Females

Parameter HR [95% CI] p-value
L12_LICHENSIMPLEX 1.208 [1.06, 1.38] 0.004
Birth year 0.991 [0.98, 1.0] 0.044

During the follow-up period (1.1.1998 — 31.12.2019), 467 out of 3488 females with L12_LICHENSIMPLEX died.

Males

Parameter HR [95% CI] p-value
L12_LICHENSIMPLEX 1.41 [1.25, 1.59] < 0.001
Birth year 0.989 [0.98, 1.0] 0.022

During the follow-up period (1.1.1998 — 31.12.2019), 651 out of 3285 males with L12_LICHENSIMPLEX died.

Mortality risk

Mortality risk for people of age

years, who have L12_LICHENSIMPLEX.

N-year risk Females Males
1 0.065% 0.25%
5 0.621% 1.792%
10 1.481% 4.38%
15 2.961% 8.242%
20 5.346% 13.364%

Relationships between endpoints

Index endpoint: L12_LICHENSIMPLEX – Lichen simplex chronicus

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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