Perineal laceration during delivery

O15_DELIV_PERIN_LACER

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O70
  • Hospital discharge: ICD-9 664
  • Hospital discharge: ICD-8 6603
  • Cause of death: ICD-10 O70
  • Cause of death: ICD-9 664
  • Cause of death: ICD-8 6603

2 out of 7 registries used, show all original rules.

7857

4. Check minimum number of events

None

7857

5. Include endpoints

None

7857

6. Filter based on genotype QC (FinnGen only)

7857

Control definitions (FinnGen only)

Control exclude
O15_COMPLIC_LAB_DELIV

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Parent code in ICD-10
O60-O75
Name in latin
Laceratio perinei intra partum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 57715 57715 -
Only index persons 57188 57188 -
Unadjusted period prevalence (%)
Whole population 1.65 1.65 -
Only index persons 2.10 2.10 -
Median age at first event (years)
Whole population - 29.53 -
Only index persons - 29.52 -

-FinnGen-

Key figures

All Female Male
Number of individuals 7857 7857 -
Unadjusted period prevalence (%) 2.68 2.68 -
Median age at first event (years) 30.14 30.14 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
6782
Matched controls
61705
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
1066.3
323.0
638
6
MBC30
NOMESCO Finland
Repair of partial rupture of perineum
68.1
323.0
1710
304
O80.8
ICD-10 Finland
Other single spontaneous delivery
5.1
323.0
1287
2684
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
4.9
323.0
4589
18473
O75.6
ICD-10 Finland
Delayed delivery after spontaneous or unspecified rupture of membranes
+∞
323.0
323
*
O81.4
ICD-10 Finland
Vacuum extractor delivery
59.5
323.0
1613
322
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
4.1
323.0
2984
10013
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
78.2
323.0
419
52
O68.0
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly
9082.7
323.0
881
*
O63.1
ICD-10 Finland
Prolonged second stage (of labour)
+∞
323.0
646
*
MAE00
NOMESCO Finland
Outlet vacuum delivery
54.9
323.0
1384
287
O70.0
ICD-10 Finland
First degree perineal laceration during delivery
5740.7
323.0
1086
*
O70.2
ICD-10 Finland
Third degree perineal laceration during delivery
+∞
323.0
757
*
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
3.3
323.0
2793
10908
SPAT1197
SPAT
Extensive health check-up of expecting family
4.6
323.0
3363
10800
66030
ICD-8 Finland
Occipital presentation
+∞
323.0
387
*
SPAT1379
SPAT
Health check-up of pregnant person
4.2
323.0
2955
9503
SPAT1380
SPAT
Postpartum check-up
4.0
323.0
2490
7746
MBC10
NOMESCO Finland
Repair of obstetric laceration of vagina
14.5
323.0
915
658
MAX99
NOMESCO Finland
Assistance to normal delivery
3.5
323.0
2412
8369
W78
ICPC
Pregnancy
4.1
323.0
3556
13177
MBC33
NOMESCO Finland
Repair of complete rupture of perineum
590.4
323.0
701
12
O72.0
ICD-10 Finland
Third-stage haemorrhage
+∞
323.0
592
*
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
3.9
323.0
3202
11486
Z39.2
ICD-10 Finland
Routine postpartum follow-up
5.0
323.0
3341
9979
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
4.0
323.0
2092
6214
O70.1
ICD-10 Finland
Second degree perineal laceration during delivery
8679.0
323.0
3752
8
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
3.8
323.0
3239
11894
WX307
NOMESCO Finland
Obstetric epidural analgesia
3.4
306.3
1835
6068
O64.0
ICD-10 Finland
Obstructed labour due to incomplete rotation of fetal head
+∞
276.3
273
*
O70.21
ICD-10 Finland
III degree perineal tear involving less than one half of external anal sphincter thickness torn during childbirth
+∞
258.0
255
*
O80.0
ICD-10 Finland
Spontaneous vertex delivery
2.4
255.0
4078
23714
Z37.0
ICD-10 Finland
Single live birth
2.9
233.8
1794
6852
O75.0
ICD-10 Finland
Maternal distress during labour and delivery
+∞
229.5
227
*
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
131.7
227.0
251
18
TMA00
NOMESCO Finland
Episiotomy
5.0
223.8
800
1616
O60
ICD-10 Finland
Preterm labour and delivery
530.0
220.6
226
*
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
2.8
211.5
1739
6865
MA3AE
NOMESCO Finland
Combined first trimester screening
3.6
208.3
1069
3026
6641B
ICD-9 Finland
Trauma to perineum and vulva during delivery, Second-degree perineal laceration
+∞
206.1
204
*
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
3.5
193.1
1042
3057
O99.80
ICD-10 Finland
The fear of childbirth
3.7
190.0
941
2573
O70.22
ICD-10 Finland
III degree perineal tear involving one half or more of external anal sphincter thickness torn during childbirth
+∞
188.8
187
*
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
5.0
187.2
655
1282
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
3.6
187.0
961
2706
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
2.8
184.7
1390
5136
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
3.3
176.5
1040
3243
O71.4
ICD-10 Finland
Obstetric high vaginal laceration
+∞
174.6
173
*
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
2.4
173.6
1837
8207
SPAT1195
SPAT
Antenatal classes
4.1
170.9
732
1752
Z34
ICD-10 Finland
Supervision of normal pregnancy
3.3
170.6
995
3075
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
2.6
169.6
1461
5822
SPAT1196
SPAT
Monitoring of normal pregnancy
2.7
167.0
1384
5386
Z39.1
ICD-10 Finland
Care and examination of lactating mother
5.7
163.4
510
870
SPAT1200
SPAT
Guidance for breast-feeding and breast care
4.2
159.4
671
1576
Z32.1
ICD-10 Finland
Pregnancy confirmed
2.4
159.0
1713
7666
Z36.8
ICD-10 Finland
Other antenatal screening
5.4
158.5
518
933
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
2.3
158.3
1774
8096
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
6.8
156.1
424
603
O73.0
ICD-10 Finland
Retained placenta without haemorrhage
+∞
155.3
154
*
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.5
152.9
1413
5815
SPAT1373
SPAT
Combined screening in early pregnancy
5.4
151.4
494
887
O63.0
ICD-10 Finland
Prolonged first stage (of labour)
+∞
144.2
143
*
W85
ICPC
Gestational diabetes
3.3
140.0
790
2360
WX306
NOMESCO Finland
Lumbar epidural anesthesy
3.0
134.8
902
3032
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2.4
132.4
1290
5411
W92
ICPC
Compl labour/ delivery livebirth
6.0
127.6
380
608
SPAT1246
SPAT
Screening of depression or other psychiatric problem
3.0
119.5
788
2612
MAC96
NOMESCO Finland
Other induction or advancement of labour
4.1
118.7
501
1169
O64.1
ICD-10 Finland
Obstructed labour due to breech presentation
1101.0
117.9
119
*
WX600
NOMESCO Finland
Single shot through catheter
7.3
112.8
289
376
8833
FHL
Correction of II ^ 0 or III ^ 0 perineumrupth or vaginal rupture
81.0
112.7
131
15
MBA04
NOMESCO Finland
Curettage of uterus after delivery
55.7
112.5
138
23
O68.1
ICD-10 Finland
Labour and delivery complicated by meconium in amniotic fluid
+∞
111.8
111
*
MBC20
NOMESCO Finland
Repair of obstetric laceration of vulva
19.1
109.4
174
85
W90
ICPC
Uncompl labour/delivery livebirth
2.5
106.8
932
3646
6640B
ICD-9 Finland
Trauma to perineum and vulva during delivery, First-degree perineal laceration
+∞
106.8
106
*
O70.3
ICD-10 Finland
Fourth degree perineal laceration during delivery
950.5
101.8
103
*
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
4.2
100.3
411
930
O73.1
ICD-10 Finland
Retained portions of placenta and membranes, without haemorrhage
+∞
99.7
99
*
O68.8
ICD-10 Finland
Labour and delivery complicated by other evidence of fetal stress
+∞
99.7
99
*
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
4.7
94.9
344
688
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
3.9
92.8
420
1039
SPAT1189
SPAT
Other ultrasound examination during pregnancy
2.9
92.1
637
2161
W84
ICPC
Pregnancy high risk
2.9
90.6
619
2080
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
4.3
89.9
360
796
W29
ICPC
Pregnancy symptom/complaint other
3.2
88.7
524
1596
O62.1
ICD-10 Finland
Secondary uterine inertia
+∞
88.6
88
*
O70.9
ICD-10 Finland
Perineal laceration during delivery, unspecified
175.3
88.0
95
5
Z36.4
ICD-10 Finland
Antenatal screening for fetal growth retardation using ultrasound and other physical methods
5.0
87.5
299
561
O48
ICD-10 Finland
Prolonged pregnancy
3.1
85.8
525
1638
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
7.0
84.6
220
292
WYA40
NOMESCO Finland
Assessment of oral health and treatment needs for family expecting first child
3.7
83.0
387
981
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
3.1
82.9
504
1565
OAA12
SPAT
NA
4.1
82.3
345
795
SPAT1375
SPAT
Structural ultrasound screening, weeks 18+0-21+6
5.0
81.4
281
533
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
2.5
81.3
711
2757
XMA22
NOMESCO Finland
General examination of pregnant woman
2.3
80.9
849
3617
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
2.2
80.6
953
4291
WW500
NOMESCO Finland
Blood transfusion
5.4
79.7
253
436
OAA11
SPAT
NA
2.8
79.3
547
1846
6642B
ICD-9 Finland
Trauma to perineum and vulva during delivery, Third-degree perineal laceration
+∞
78.5
78
*
O61.0
ICD-10 Finland
Failed medical induction of labour
+∞
77.5
77
*
O61.8
ICD-10 Finland
Other failed induction of labour
+∞
76.5
76
*
XJH00
NOMESCO Finland
Transanal ultrasonography
8.4
75.0
173
191
O47.9
ICD-10 Finland
False labour, unspecified
4.0
73.2
317
752
6645B
ICD-9 Finland
Trauma to perineum and vulva during delivery, Vulval and perineal haematoma
+∞
72.4
72
*
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
3.1
72.4
441
1369
O68.2
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly with meconium in amniotic fluid
+∞
68.4
68
*
JHC00
NOMESCO Finland
Suture of anal sphincter
220.6
67.8
72
*
O34.7
ICD-10 Finland
Maternal care for abnormality of vulva and perineum
61.3
66.5
80
12
WX320
NOMESCO Finland
Spinalanesthesy
1.9
64.7
1044
5297
WX322
NOMESCO Finland
Combined spinal-epidural analgesia in obstetrics
3.4
61.8
320
881
WX230
NOMESCO Finland
Plexus blockade of nervus pudendus
4.1
61.6
256
585
O66.0
ICD-10 Finland
Obstructed labour due to shoulder dystocia
+∞
61.4
61
*
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
3.9
60.3
267
646
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
5.8
60.2
180
289
MAC00
NOMESCO Finland
Rupture of amniotic membrane
11.0
57.5
114
96
SPAT1357
SPAT
Monitoring of problem during pregnancy
2.6
57.5
451
1637
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.9
56.8
897
4497
O64.8
ICD-10 Finland
Obstructed labour due to other malposition and malpresentation
530.7
56.6
58
*
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
2.6
55.8
447
1640
O75.7
ICD-10 Finland
Vaginal delivery following previous caesarean section
+∞
52.3
52
*
MAE03
NOMESCO Finland
Mid-cavity or high vacuum delivery
41.0
52.1
67
15
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
2.0
51.3
695
3274
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
3.0
50.5
316
996
N05AH04
ATC
quetiapine; oral
0.5
49.6
521
8481
WX234
NOMESCO Finland
Paracervical blockade
2.4
48.3
445
1759
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
2.2
48.2
544
2369
O71.3
ICD-10 Finland
Obstetric laceration of cervix
438.0
46.6
48
*
R3110
NOMESCO Finland
Psychosocial training
3.5
46.0
229
611
O68.3
ICD-10 Finland
Labour and delivery complicated by biochemical evidence of fetal stress
+∞
45.2
45
*
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
3.2
44.3
251
739
O02.1
ICD-10 Finland
Missed abortion
1.9
43.8
667
3281
MBC00
NOMESCO Finland
Repair of obstetric laceration of cervix uteri
74.9
42.1
49
6
O32.1
ICD-10 Finland
Maternal care for breech presentation
2.2
40.9
468
2048
O62.0
ICD-10 Finland
Primary inadequate contractions
+∞
40.2
40
*
O82.11
ICD-10 Finland
Childbirth with an emergency caesarean section in an emergency
11.2
40.1
78
64
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
2.3
40.0
379
1517
MAW96
NOMESCO Finland
Other operation in pregnancy or at delivery
7.6
39.6
96
116
O69.1
ICD-10 Finland
Labour and delivery complicated by cord around neck, with compression
+∞
39.2
39
*
Z12.4
ICD-10 Finland
Special screening examination for neoplasm of cervix
2.6
38.4
289
1022
6611B
ICD-9 Finland
Abnormality of forces of labour, Secondary uterine inertia
+∞
38.2
38
*
R15
ICD-10 Finland
Faecal incontinence
4.5
37.9
139
283
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
0.3
37.6
114
2909
XJH10
NOMESCO Finland
Anorectal manometry
13.0
37.5
68
48
6622B
ICD-9 Finland
Long labour, Prolonged second stage
+∞
37.2
37
*
OAA10
SPAT
NA
2.6
36.7
283
1013
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
2.3
36.0
345
1387
O86.0
ICD-10 Finland
Infection of obstetric surgical wound
4.9
35.8
121
226
MAC02
NOMESCO Finland
Rupture of aminiotic membrane for advancement of labor
5.1
35.1
115
208
O36.9
ICD-10 Finland
Maternal care for fetal problem, unspecified
3.7
34.9
159
396
O67.9
ICD-10 Finland
Intrapartum haemorrhage, unspecified
+∞
34.2
34
*
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
2.8
33.9
233
779
ZXH09
SPAT
NA
3.0
33.7
206
640
O26.7
ICD-10 Finland
Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
3.4
33.7
173
475
MAA40
NOMESCO Finland
Puncture of fetus
6.3
33.5
92
134
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
1.5
33.1
1648
11146
Z39
ICD-10 Finland
Postpartum care and examination
3.2
33.0
183
532
Z32
ICD-10 Finland
Pregnancy examination and test
3.5
32.4
160
426
O86.1
ICD-10 Finland
Other infection of genital tract following delivery
4.3
32.0
122
259
O71.7
ICD-10 Finland
Obstetric haematoma of pelvis
299.3
31.7
33
*
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
2.9
31.5
206
667
6522B
ICD-9 Finland
Malposition and malpresentation of foetus, Breech presentation without mention of version[PRAESENTATIO CLUNIUM,SYNNYTYKSEN AIKANA]
+∞
31.2
31
*
O66.5
ICD-10 Finland
Failed application of vacuum extractor and forceps, unspecified
+∞
31.2
31
*
8836
FHL
Evacuation of a vulva or paravaginal hematoma
65.9
30.5
36
5
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
2.6
30.5
242
881
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
2.5
30.5
249
922
N06AX16
ATC
venlafaxine; oral
0.6
30.2
485
7134
6660A
ICD-9 Finland
Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM STADII III]
+∞
30.2
30
*
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
2.5
29.7
247
925
SPAT1315
SPAT
Periodic health check-up of children and adolescents
1.9
29.6
490
2472
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
2.1
29.6
349
1544
O41.8
ICD-10 Finland
Other specified disorders of amniotic fluid and membranes
7.1
29.4
74
96
TQW30
NOMESCO Finland
Acupuncture
4.5
29.2
108
223
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.4
29.1
2692
20211
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
2.6
28.6
218
778
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
28.6
2663
19998
N05AX12
ATC
aripiprazole; systemic
0.3
28.5
84
2172
N05AH03
ATC
olanzapine; systemic
0.4
28.3
107
2494
O62.3
ICD-10 Finland
Precipitate labour
+∞
28.1
28
*
N06AX11
ATC
mirtazapine; oral
0.7
27.8
1078
13271
MAC99
NOMESCO Finland
Other augmentation of labor
73.2
27.6
32
*
O41.0
ICD-10 Finland
Oligohydramnios
2.5
27.5
226
840
MBC40
NOMESCO Finland
Revision of paravaginal or vulvar haematoma after delivery or abortion
26.7
27.1
38
13
O82.0
ICD-10 Finland
Delivery by elective caesarean section
1.9
27.1
404
1962
O91.2
ICD-10 Finland
Nonpurulent mastitis associated with childbirth
2.8
27.1
180
590
SPAT1324
SPAT
Screening procedure
1.4
26.6
1778
12605
8832
FHL
Manual placenta removal and associated scraping
132.5
26.6
29
*
MAE20
NOMESCO Finland
Failed vacuum delivery
91.4
26.5
30
*
O75.2
ICD-10 Finland
Pyrexia during labour, not elsewhere classified
+∞
26.1
26
*
6441A
ICD-9 Finland
Early or threatened labour, Other threatened labour
+∞
26.1
26
*
F29
ICD-10 Finland
Unspecified nonorganic psychosis
0.3
26.0
57
1687
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
2.6
25.8
199
714
O62.2
ICD-10 Finland
Other uterine inertia
68.6
25.7
30
*
8801
FHL
Suction cup delivery
4.9
25.5
85
158
N05AX08
ATC
risperidone; systemic
0.4
25.4
94
2207
G03GA05
ATC
follitropin alfa; parenteral
1.9
25.1
376
1831
OAB47
SPAT
NA
2.3
25.0
247
1008
SPAT1187
SPAT
General ultrasound examination in early pregnancy
3.0
24.7
152
475
X23
ICPC
Fear sexually transm dis female
0.6
24.6
359
5423
SPAT1190
SPAT
Insertion or removal of intrauterine contraceptive device
1.5
24.1
811
5000
SPAT1128
SPAT
Instruction of pelvic floor / sphincter exercises
3.3
24.1
126
353
JHC10
NOMESCO Finland
Reconstruction of anal sphincter without graft
32.5
24.0
32
9
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
2.2
24.0
241
994
MBC96
NOMESCO Finland
Other repair of obstetric laceration
118.7
23.6
26
*
O47.1
ICD-10 Finland
False labour at or after 37 completed weeks of gestation
1.8
23.6
420
2171
LFE20
NOMESCO Finland
Suture of perineum
31.5
23.1
31
9
W18
ICPC
Post-partum symptom/complaint other
4.1
23.0
93
211
N05CF01
ATC
zopiclone; oral
0.7
22.9
755
9606
SPAT1381
SPAT
Extensive health check-up at 4 months of age
3.7
22.8
104
262
O41.1
ICD-10 Finland
Infection of amniotic sac and membranes
5.6
22.7
68
112
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
1.9
22.7
343
1673
OAA41
SPAT
NA
2.9
22.3
139
439
63497
ICD-8 Finland
Other complications of pregnancy, Partus prematurus imminens, alibi non classificabilis
+∞
22.1
22
*
6654B
ICD-9 Finland
Other obstetrical trauma, High vaginal laceration
+∞
22.1
22
*
SPAT1236
SPAT
Informing family of child’s disability
3.3
21.8
112
310
O71.8
ICD-10 Finland
Other specified obstetric trauma
76.1
21.7
25
*
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
2.8
21.5
147
492
O42.1
ICD-10 Finland
Premature rupture of membranes, onset of labour after 24 hours
3.0
21.3
129
401
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
2.9
21.3
135
433
OAA70
SPAT
NA
3.1
21.2
120
355
6440B
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS]
+∞
21.1
21
*
6648B
ICD-9 Finland
Trauma to perineum and vulva during delivery, Other specified trauma to perineum and vulva
+∞
21.1
21
*
N05BA04
ATC
oxazepam; oral
0.7
21.0
872
10682
Z71.9
ICD-10 Finland
Counselling, unspecified
1.8
20.8
354
1800
N97.9
ICD-10 Finland
Female infertility, unspecified
1.5
20.6
665
4056
H01CC01
ATC
ganirelix; parenteral
1.9
20.2
311
1530
SPAT1382
SPAT
Extensive health check-up at 18 months of age
3.5
20.1
96
252
M01AH05
ATC
etoricoxib; oral
0.8
19.9
2414
25552
N06AX12
ATC
bupropion; oral
0.6
19.8
227
3653
SPAT1308
SPAT
Sexual health counselling
1.3
19.5
1822
13480
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.4
19.3
1073
7310
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
2.8
19.2
123
398
O65.5
ICD-10 Finland
Obstructed labour due to abnormality of maternal pelvic organs
+∞
19.1
19
*
O68.9
ICD-10 Finland
Labour and delivery complicated by fetal stress, unspecified
+∞
19.1
19
*
N05BA01
ATC
diazepam; systemic, rectal
0.6
18.9
232
3669
SPAT1391
SPAT
Counselling and guidance related to family situation
2.4
18.7
161
615
F20.9
ICD-10 Finland
Schizophrenia, unspecified
0.1
18.7
5
563
O47
ICD-10 Finland
False labour
2.8
18.6
123
406
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
1.6
18.4
463
2652
Z10.8
ICD-10 Finland
Routine general health check-up of other defined subpopulations
1.8
18.3
316
1617
N05CF02
ATC
zolpidem; oral
0.7
18.2
529
6917
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
2.5
18.1
145
534
G03GA01
ATC
chorionic gonadotrophin; parenteral
1.7
18.1
427
2405
N03AX09
ATC
lamotrigine; oral
0.5
17.7
154
2678
W05
ICPC
Pregnancy vomiting/nausea
2.6
17.5
131
465
N02AX02
ATC
tramadol; systemic, rectal
0.7
17.5
1115
12855
SPAT1192
SPAT
Gynaecological examination
1.3
17.5
1310
9358
P72
ICPC
Schizophrenia
0.1
17.3
*
507
6660C
ICD-9 Finland
Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM CUM RETENT PLAC PARTIALI]
+∞
17.1
17
*
SPAT1312
SPAT
General health counselling
1.3
17.0
2074
15845
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
2.0
16.9
209
945
N61
ICD-10 Finland
Inflammatory disorders of breast
1.8
16.8
273
1370
OAB30
SPAT
NA
3.3
16.6
85
237
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
2.1
16.5
192
848
SPAT1393
SPAT
Guidance to support interaction between parent and child
3.2
16.3
87
250
N06AB10
ATC
escitalopram; oral
0.8
16.2
1058
12173
N05AH02
ATC
clozapine; systemic
0.2
16.2
14
689
T36
ICD-10 Finland
Poisoning by systemic antibiotics
0.5
16.1
103
1974
6660B
ICD-9 Finland
Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM CUM RETENT PLAC TOTALI]
+∞
16.1
16
*
6528B
ICD-9 Finland
Malposition and malpresentation of foetus, Other specified malposition or malpresentation[MUUT VIRHEASENNOT JA -TARJONNAT, SYNNYTYKSEN AIKANA]
+∞
16.1
16
*
SPAT1389
SPAT
Visit based on need for special support
1.8
16.0
266
1345
N06AB03
ATC
fluoxetine; oral
0.6
15.9
365
5000
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
1.8
15.9
296
1553
O90.1
ICD-10 Finland
Disruption of perineal obstetric wound
5.8
15.8
45
71
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
1.8
15.4
285
1496
O20.0
ICD-10 Finland
Threatened abortion
1.9
15.1
234
1154
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
2.2
15.1
156
654
O66.8
ICD-10 Finland
Other specified obstructed labour
+∞
15.1
15
*
O66.2
ICD-10 Finland
Obstructed labour due to unusually large fetus
+∞
15.1
15
*
W27
ICPC
Fear of complications of pregnancy
2.4
15.0
134
524
O32.2
ICD-10 Finland
Maternal care for transverse and oblique lie
3.4
15.0
73
197
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
2.1
14.9
169
741
ZXA00
NOMESCO Finland
Right side
0.7
14.8
468
6036
WZB00
SPAT
NA
0.6
14.8
199
3077
N06AB06
ATC
sertraline; oral
0.7
14.7
420
5515
Z76.0
ICD-10 Finland
Issue of repeat prescription
0.7
14.6
511
6471
TLW00
NOMESCO Finland
Insemination
1.8
14.4
232
1165
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
0.1
14.2
7
502
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
0.2
14.1
11
577
O67.8
ICD-10 Finland
Other intrapartum haemorrhage
+∞
14.1
14
*
6661A
ICD-9 Finland
Postpartum haemorrhage, Other immediate postpartum haemorrhage[HAEMORRHAGIA POST PARTUM ATONICA UTERI]
+∞
14.1
14
*
6670A
ICD-9 Finland
Retained placenta or membranes, without haemorrhage, Retained placenta without haemorrhage
+∞
14.1
14
*
65300
ICD-8 Finland
Occipital presentation
+∞
14.1
14
*
N81.6
ICD-10 Finland
Rectocele
1.9
14.0
221
1098
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.6
13.9
393
2319
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
0.5
13.8
148
2425
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
0.6
13.7
236
3440
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
0.7
13.7
376
4974
O30.0
ICD-10 Finland
Twin pregnancy
2.3
13.6
127
510
O35.9
ICD-10 Finland
Maternal care for (suspected) fetal abnormality and damage, unspecified
2.4
13.5
112
423
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
0.4
13.3
52
1191
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
0.5
13.3
76
1512
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
2.0
13.2
170
786
F32.9
ICD-10 Finland
Depressive episode, unspecified
0.7
13.2
581
7096
TLW12
NOMESCO Finland
Insertion of frozen embryo
1.9
13.1
188
904
SPAT1188
SPAT
Monitoring of foetal growth
3.2
13.1
68
194
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.5
13.1
80
1556
O75.3
ICD-10 Finland
Other infection during labour
+∞
13.1
13
*
O64.9
ICD-10 Finland
Obstructed labour due to malposition and malpresentation, unspecified
+∞
13.1
13
*
6644B
ICD-9 Finland
Trauma to perineum and vulva during delivery, Unspecified perineal laceration
+∞
13.1
13
*
MAA00
NOMESCO Finland
Amniocentesis
1.9
13.0
181
860
L02BG04
ATC
letrozole; oral
1.6
13.0
368
2172
I10
ICD-10 Finland
Essential (primary) hypertension
0.7
12.9
704
8335
N03AX12
ATC
gabapentin; oral
0.7
12.9
322
4338
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
0.1
12.9
5
425
N05CD07
ATC
temazepam; oral
0.5
12.9
76
1496
N03AX16
ATC
pregabalin; oral
0.7
12.7
565
6895
XJG12
NOMESCO Finland
Transrectal endoscopic ultrasonography
11.0
12.7
24
20
Z20.2
ICD-10 Finland
Contact with and exposure to infections with a predominantly sexual mode of transmission
0.5
12.7
91
1677
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
0.7
12.6
507
6288
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
1.4
12.6
692
4686
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
0.1
12.5
6
435
O90.8
ICD-10 Finland
Other complications of the puerperium, not elsewhere classified
6.5
12.5
32
45
MBA05
NOMESCO Finland
Curettage of uterus after abortion
2.2
12.3
120
494
N05AN01
ATC
lithium; oral
0.3
12.3
36
931
N05AA02
ATC
levomepromazine; systemic
0.4
12.3
38
960
N05BA06
ATC
lorazepam; systemic, sublingual
0.4
12.3
42
1017
O65.4
ICD-10 Finland
Obstructed labour due to fetopelvic disproportion, unspecified
45.6
12.3
15
*
N97.0
ICD-10 Finland
Female infertility associated with anovulation
1.7
12.3
242
1295
O84.8
ICD-10 Finland
Other multiple delivery
6.4
12.3
32
46
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
2.0
12.3
156
717
O85
ICD-10 Finland
Puerperal sepsis
2.5
12.3
92
331
8831
FHL
Uterine exploration and / or scraping or suction emptying (ad 24 hours)
17.3
12.2
19
10
A10AA01
ATC
NA
0.3
12.2
28
809
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
0.7
12.1
491
6081
SPAT1193
SPAT
Pap smear
1.3
12.1
1096
8006
6620B
ICD-9 Finland
Long labour, Prolonged first stage
+∞
12.1
12
*
O61.1
ICD-10 Finland
Failed instrumental induction of labour
+∞
12.1
12
*
W94
ICPC
Puerperal mastitis
2.4
12.0
98
370
M03BX02
ATC
tizanidine; oral
0.8
12.0
3128
31271
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
0.4
12.0
49
1103
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
2.6
12.0
84
292
MAF00
NOMESCO Finland
Outlet forceps cephalic delivery
118.5
12.0
13
*
O64.3
ICD-10 Finland
Obstructed labour due to brow presentation
118.5
12.0
13
*
N81.1
ICD-10 Finland
Cystocele
1.8
11.8
191
962
WZA10
SPAT
NA
0.2
11.7
10
492
TLW10
NOMESCO Finland
Transfer of fresh embryo
1.8
11.7
190
960
A10AA02
ATC
NA
0.3
11.7
29
805
Z31.1
ICD-10 Finland
Artificial insemination
3.0
11.6
68
211
F32
ICD-10 Finland
Depressive episode
0.6
11.6
199
2900
L17
ICPC
Foot/toe symptom/complaint
0.8
11.6
720
8379
6500B
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
0.7
11.6
496
6092
O23.5
ICD-10 Finland
Infections of the genital tract in pregnancy
2.3
11.5
108
435
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
1.7
11.5
259
1443
103
Kela drug reimbursment
Diabetes, insulin-treated
0.7
11.5
299
4003
O86.8
ICD-10 Finland
Other specified puerperal infections
3.9
11.5
46
107
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
0.4
11.4
39
943
M03BC01
ATC
orphenadrine (citrate); systemic
0.8
11.4
1003
11183
G47.3
ICD-10 Finland
Sleep apnoea
0.7
11.4
308
4091
F40.1
ICD-10 Finland
Social phobias
0.4
11.4
59
1212
WX110
SPAT
NA
0.5
11.2
101
1737
G03GA06
ATC
follitropin beta; parenteral
1.7
11.1
224
1208
N03AG01
ATC
valproic acid; systemic, rectal
0.6
11.1
138
2170
8811
FHL
Cesarean section
2.2
11.1
113
476
SPAT1374
SPAT
Serum screening during second trimester
14.9
11.0
18
11
ZXH06
SPAT
NA
2.1
11.0
117
500
N02AJ06
ATC
codeine and paracetamol; systemic
0.8
11.0
1483
15798
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
1.9
11.0
167
825
H3603, E103
ICD-10 Finland
NA
0.1
11.0
*
330
O80.9
ICD-10 Finland
Single spontaneous delivery, unspecified
2.2
11.0
107
441
W03
ICPC
Antepartum bleeding
2.3
10.8
96
379
215
Kela drug reimbursment
Diabetes, non-insulin-treated
0.7
10.8
298
3947
O20.8
ICD-10 Finland
Other haemorrhage in early pregnancy
2.9
10.8
64
201
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
0.4
10.8
49
1056
O92.7
ICD-10 Finland
Other and unspecified disorders of lactation
3.6
10.8
47
118
WW200
SPAT
NA
1.4
10.8
568
3815
F32.1
ICD-10 Finland
Moderate depressive episode
0.6
10.7
234
3240
K05.31
ICD-10 Finland
Periodontitis pronounced
0.5
10.7
84
1503
O24
ICD-10 Finland
Diabetes mellitus in pregnancy
3.4
10.7
51
138
C07AA05
ATC
propranolol; systemic
0.8
10.6
834
9431
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
2.9
10.6
66
212
GD1AA
NOMESCO Finland
Thorax X-ray examination
0.8
10.6
966
10739
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
0.3
10.6
26
723
M03BC51
ATC
orphenadrine, combinations; systemic
0.8
10.5
1137
12401
W12
ICPC
Contraception intrauterine
1.3
10.5
1211
9106
W78
ICD-10 Finland
Inhalation of gastric contents
4.6
10.4
35
69
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
1.9
10.4
148
713
WX740
NOMESCO Finland
Nitrogen oxide therapy
3.4
10.3
49
132
F34.1
ICD-10 Finland
Dysthymia
0.5
10.3
88
1532
O40
ICD-10 Finland
Polyhydramnios
2.3
10.2
94
379
M01AB05
ATC
diclofenac; systemic, rectal
0.8
10.2
3117
30934
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
1.7
10.1
190
1007
O69.0
ICD-10 Finland
Labour and delivery complicated by prolapse of cord
+∞
10.0
10
*
6610B
ICD-9 Finland
Abnormality of forces of labour, Primary uterine inertia
+∞
10.0
10
*
O64.2
ICD-10 Finland
Obstructed labour due to face presentation
+∞
10.0
10
*
O69.2
ICD-10 Finland
Labour and delivery complicated by other cord entanglement, with compression
+∞
10.0
10
*
ZXA05
NOMESCO Finland
Left side
0.7
9.9
462
5607
X59
ICD-10 Finland
Exposure to unspecified factor
0.7
9.9
521
6212
MAB20
NOMESCO Finland
Failed external version
2.1
9.8
114
510
ZYC02
SPAT
NA
0.4
9.7
51
1041
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
0.5
9.7
86
1481
O21.0
ICD-10 Finland
Mild hyperemesis gravidarum
2.1
9.7
103
444
NE1AG
NOMESCO Finland
MRI pelvimetry with high intensity magnet
2.6
9.6
70
251
O21
ICD-10 Finland
Excessive vomiting in pregnancy
2.2
9.6
93
386
O30.01
ICD-10 Finland
Twin pregnancy with a shared chorionic sac and a separate amniotic sac
6.2
9.6
25
37
P76
ICPC
Depressive disorder
0.7
9.5
279
3654
SPAT1263
SPAT
Sampling
1.2
9.5
2521
20562
N06AX03
ATC
mianserin; oral
0.4
9.4
47
976
N06AX26
ATC
vortioxetine; oral
0.6
9.4
200
2780
O28.3
ICD-10 Finland
Abnormal ultrasonic finding on antenatal screening of mother
2.4
9.4
75
283
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
0.7
9.4
466
5600
N05AB03
ATC
perphenazine; systemic, rectal
0.4
9.2
48
982
O34.3
ICD-10 Finland
Maternal care for cervical incompetence
3.2
9.2
46
130
Z46.9
ICD-10 Finland
Fitting and adjustment of unspecified device
4.6
9.2
31
62
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
0.6
9.2
143
2127
H01CA02
ATC
nafarelin; nasal
1.6
9.1
242
1412
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
0.7
9.1
306
3906
MWA00
NOMESCO Finland
Repair of wound dehiscence in obstetric surgery
6.4
9.0
23
33
R4190
NOMESCO Finland
Nutritional therapy
0.4
9.0
44
920
T89
ICPC
Diabetes insulin dependent
0.5
9.0
64
1181
WX402
NOMESCO Finland
General anaesthesia
0.8
9.0
529
6211
SPAT1273
SPAT
Structured assessment of psychoactive substance / tobacco use
1.5
9.0
295
1810
Z37.2
ICD-10 Finland
Twins, both liveborn
4.3
9.0
32
68
JH1AE
NOMESCO Finland
Anus structural ultrasound examination
19.7
8.9
13
6
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
0.8
8.9
684
7759
XF400
NOMESCO Finland
ECG with 12 standard connections
0.7
8.8
202
2766
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
0.5
8.8
53
1030
XA800
NOMESCO Finland
Neuropsychological investigation
0.5
8.7
51
1003
F61.0
ICD-10 Finland
Mixed personality disorders
0.4
8.7
30
721
SPAT1383
SPAT
Extensive health check-up at 4 years of age
2.0
8.7
103
464
W82
ICPC
Abortion spontaneous
2.1
8.7
94
409
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
0.6
8.7
163
2329
IHZ02
SPAT
NA
0.3
8.7
17
525
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
0.7
8.7
331
4141
O90.2
ICD-10 Finland
Haematoma of obstetric wound
7.3
8.7
20
25
N06AB04
ATC
citalopram; systemic
0.8
8.7
789
8786
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
0.4
8.6
26
657
EB1AA
SPAT
NA
0.6
8.6
97
1564
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
0.2
8.6
11
427
Z35.1
ICD-10 Finland
Supervision of pregnancy with history of abortive outcome
2.7
8.5
58
199
C09AA05
ATC
ramipril; oral
0.6
8.5
156
2237
SPAT1325
SPAT
Vaccination
1.2
8.5
1365
10613
A02BC02
ATC
pantoprazole; systemic
0.9
8.4
2616
26078
N81.2
ICD-10 Finland
Incomplete uterovaginal prolapse
1.8
8.4
146
759
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
0.4
8.3
43
881
N07BA03
ATC
varenicline; oral
0.6
8.2
111
1710
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
0.5
8.2
73
1257
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
0.5
8.2
80
1339
P06
ICPC
Sleep disturbance
0.7
8.2
323
4022
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
0.8
8.2
1921
19590
M79.6
ICD-10 Finland
Pain in limb
0.8
8.2
1347
14146
N06AX21
ATC
duloxetine; oral
0.7
8.2
336
4155
L12
ICPC
Hand/finger symptom/complaint
0.7
8.1
423
5053
O90.9
ICD-10 Finland
Complication of the puerperium, unspecified
4.4
8.1
28
58
C08CA01
ATC
amlodipine; oral
0.7
8.1
328
4065
8839
FHL
Other measure in this category
82.0
8.1
9
*
8842
FHL
Peritoneal and vaginal wound revision
25.1
8.1
11
*
O81.0
ICD-10 Finland
Low forceps delivery
25.1
8.1
11
*
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
1.6
8.0
202
1164
O41.9
ICD-10 Finland
Disorder of amniotic fluid and membranes, unspecified
3.0
8.0
44
134
O75.5
ICD-10 Finland
Delayed delivery after artificial rupture of membranes
+∞
8.0
8
*
65310
ICD-8 Finland
Occipital presentation
+∞
8.0
8
*
65210
ICD-8 Finland
Occipital presentation
+∞
8.0
8
*
65696
ICD-8 Finland
Delivery complicated by malpresentation of foetus, Complete or incomplete breech presentation
+∞
8.0
8
*
6534B
ICD-9 Finland
Disproportion, Foetopelvic disproportion[DISPROPORTIO FOETOPELVICA,SYNNYTYKSEN AIKANA]
+∞
8.0
8
*
O74.5
ICD-10 Finland
Spinal and epidural anaesthesia-induced headache during labour and delivery
+∞
8.0
8
*
SPAT1392
SPAT
Counselling and guidance related to couple relationship
2.2
8.0
79
331
LEF03
NOMESCO Finland
Posterior colporrpahy with sutures for primary rectocele
2.0
8.0
102
477
N07BB01
ATC
disulfiram; oral
0.5
8.0
46
905
HANKE
NOMESCO Finland
NA
4.9
8.0
25
47
TLW14
NOMESCO Finland
ICSI
2.1
7.9
88
387
Z25.1
ICD-10 Finland
Need for immunization against influenza
1.6
7.9
207
1204
O30.00
ICD-10 Finland
Twin pregnancy with separate amniotic and chorionic sacs
3.0
7.9
45
138
N17
ICPC
Vertigo/dizziness
0.7
7.9
217
2867
N05BE01
ATC
buspirone; oral
0.4
7.8
35
754
WX725
NOMESCO Finland
Noninvasive ventilation
0.5
7.8
56
1029
R5140
NOMESCO Finland
Monitoring the use of the aid
0.6
7.8
101
1570
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
0.5
7.8
71
1213
C03CA01
ATC
furosemide; systemic
0.7
7.7
191
2577
F33.1
ICD-10 Finland
Recurrent depressive disorder, current episode moderate
0.6
7.7
115
1728
A10AE05
ATC
insulin detemir; parenteral
0.5
7.6
72
1216
O44.0
ICD-10 Finland
Placenta praevia specified as without haemorrhage
2.2
7.6
71
290
N05AD01
ATC
haloperidol; systemic
0.3
7.6
17
494
W19
ICPC
Lactation symptom/complaint
2.5
7.6
56
203
F20.39
ICD-10 Finland
Undifferentiated schizophrenia UNS
0.0
7.6
*
205
C07AB07
ATC
bisoprolol; oral
0.8
7.6
801
8783
O26.9
ICD-10 Finland
Pregnancy-related condition, unspecified
2.4
7.5
59
221
F51.0
ICD-10 Finland
Nonorganic insomnia
0.8
7.5
600
6785
N05AF03
ATC
chlorprothixene; systemic
0.4
7.5
39
797
N06AA09
ATC
amitriptyline; systemic
0.6
7.5
146
2064
C09CA01
ATC
losartan; oral
0.7
7.5
253
3227
121
Kela drug reimbursment
Severe hypofunction of sexual glands
0.3
7.5
18
503
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
2.0
7.4
89
406
B18.2
ICD-10 Finland
Chronic viral hepatitis C
0.2
7.4
8
341
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
0.4
7.4
34
723
MA2AE
SPAT
NA
3.6
7.4
31
78
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
1.8
7.3
109
540
N05AE04
ATC
ziprasidone; systemic
0.2
7.3
9
357
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
1.6
7.3
165
930
F60.9
ICD-10 Finland
Personality disorder, unspecified
0.4
7.2
30
663
P99
ICPC
Psychological disorders other
0.6
7.2
75
1229
O71.9
ICD-10 Finland
Obstetric trauma, unspecified
72.9
7.1
8
*
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
0.0
7.1
*
190
F20.04
ICD-10 Finland
Paranoid schizophrenia with partial recurrence
0.0
7.1
*
160
O24.1
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, non-insulin-dependent
2.6
7.1
49
172
6643B
ICD-9 Finland
Trauma to perineum and vulva during delivery, Fourth-degree perineal laceration
+∞
7.0
7
*
O71.0
ICD-10 Finland
Rupture of uterus before onset of labour
+∞
7.0
7
*
6631A
ICD-9 Finland
Umbilical cord complications, Cord around neck, with compression
+∞
7.0
7
*
6535B
ICD-9 Finland
Disproportion, Unusually large foetus causing disproportion[EPÄTAVALLISEN ISO SIKIÖ (YLI 4500 G), SYNN AIKANA]
+∞
7.0
7
*
KMAK
NOMESCO Finland
NA
0.9
7.0
3266
31817
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
0.4
7.0
33
699
8802
FHL
Forceps delivery
12.1
7.0
12
9
C10AA01
ATC
simvastatin; oral
0.7
7.0
285
3526
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.4
6.9
28
625
P74
ICPC
Anxiety disorder/anxiety state
0.7
6.9
170
2293
SPAT1311
SPAT
Counselling and guidance related to occupational health
1.5
6.9
208
1258
M25.5
ICD-10 Finland
Pain in joint
0.8
6.9
1166
12240
G03DC03
ATC
lynestrenol; oral
0.5
6.9
62
1060
O34.1
ICD-10 Finland
Maternal care for tumour of corpus uteri
2.8
6.8
41
134
Z01.0
ICD-10 Finland
Examination of eyes and vision
0.8
6.8
409
4792
O03.3
ICD-10 Finland
Spontaneous abortion, Incomplete, with other and unspecified complications
2.7
6.8
42
140
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
0.6
6.8
126
1801
TAB20
NOMESCO Finland
Epidural puncture
3.0
6.8
37
114
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
1.3
6.8
405
2783
F31.8
ICD-10 Finland
Other bipolar affective disorders
0.5
6.8
54
954
R05
ICPC
Cough
0.8
6.7
897
9625
O92.4
ICD-10 Finland
Hypogalactia
6.2
6.7
17
25
TKC20
NOMESCO Finland
Catheterisation of bladder
1.6
6.7
153
863
L16
ICPC
Ankle symptom/complaint
0.7
6.7
269
3335
MBB10
NOMESCO Finland
Packing of delivered uterus
10.9
6.7
12
10
H04AA01
ATC
glucagon; nasal, parenteral
0.5
6.7
51
915
EBA05
NOMESCO Finland
Complicated extraction of tooth
0.8
6.6
603
6726
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
0.6
6.6
73
1179
LEF13
NOMESCO Finland
Colpoperineoplasty and vaginal hysterectomy
2.0
6.6
78
356
Z31.2
ICD-10 Finland
In vitrofertilization
2.0
6.6
78
356
S18
ICPC
Laceration/cut
0.8
6.5
1210
12619
D25.9
ICD-10 Finland
Leiomyoma of uterus, unspecified
0.7
6.5
249
3112
XF402
NOMESCO Finland
ECG with work load test
0.6
6.5
77
1224
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
0.1
6.5
*
225
SPAT1262
SPAT
Handing over of treatment supplies
1.3
6.5
485
3440
N06CA01
ATC
amitriptyline and psycholeptics; systemic
0.7
6.5
200
2589
P29
ICPC
Psychological sympt/compl other
0.7
6.5
258
3207
A46
ICD-10 Finland
Erysipelas
0.6
6.5
133
1858
N03AE01
ATC
clonazepam; systemic
0.6
6.5
96
1440
MAG96
NOMESCO Finland
Other breech delivery
6.3
6.5
16
23
R60.9
ICD-10 Finland
Oedema, unspecified
0.5
6.4
47
852
E66.01
ICD-10 Finland
Obesity due to excess calories
1.3
6.4
479
3405
O26
ICD-10 Finland
Maternal care for other conditions predominantly related to pregnancy
9.9
6.4
12
11
WX110
NOMESCO Finland
Local anesthesy
0.9
6.4
4037
38667
A77
ICPC
Viral disease other/NOS
1.4
6.4
244
1553
N89.8
ICD-10 Finland
Other specified noninflammatory disorders of vagina
2.3
6.3
57
231
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
0.7
6.3
267
3283
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
0.2
6.3
7
294
F90.0
ICD-10 Finland
Disturbance of activity and attention
0.6
6.2
117
1665
A02BC01
ATC
omeprazole; systemic
1.2
6.2
1063
8295
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
0.3
6.2
14
404
SPAT1284
SPAT
Extensive health certificate
0.6
6.2
67
1086
188
Kela drug reimbursment
Psychosis requiring demanding treatment
0.2
6.2
5
255
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
0.2
6.2
8
309
IDY03
NOMESCO Finland
Systematic individual therapy, cognitive-behavioural
0.6
6.2
116
1651
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
0.6
6.2
107
1550
P15
ICPC
Chronic alcohol abuse
0.4
6.2
20
488
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
0.5
6.1
50
878
J01DB01
ATC
cefalexin; oral
1.2
6.1
5057
44264
6690A
ICD-9 Finland
Other complications of labour and delivery, not elsewhere classified, Maternal distress
+∞
6.0
6
*
6522A
ICD-9 Finland
Malposition and malpresentation of foetus, Breech presentation without mention of version[PRAESENTATIO CLUNIUM,RASKAUDEN AIKANA]
+∞
6.0
6
*
6524B
ICD-9 Finland
Malposition and malpresentation of foetus, Face or brow presentation[HABITUS DEFLEXIONIS,SYNNYTYKSEN AIKANA]
+∞
6.0
6
*
6671A
ICD-9 Finland
Retained placenta or membranes, without haemorrhage, Retained portions of placenta or membranes, without haemorrhage
+∞
6.0
6
*
P98
ICPC
Psychosis NOS/other
0.2
6.0
*
233
EB1AA
NOMESCO Finland
Tooth X-ray examination
0.9
6.0
2851
27861
F41.1
ICD-10 Finland
Generalized anxiety disorder
0.7
6.0
245
3028

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1999
5255
4.21
307.65
1.5
1.4
—
—
—
0
0
4076
20282
2.64
307.65
1.9
1.7
—
—
—
0
0
2390
6869
4.02
307.65
1.5
1.4
—
—
—
0
0
2258
8613
2.88
307.65
2.5
2.0
—
—
—
0
0
3830
17827
2.78
307.65
1.7
1.7
—
—
—
0
0
958
2487
3.77
272.13
1.2
1.2
—
—
—
0
0
1379
4518
3.09
271.31
1.5
1.4
—
—
—
0
0
1373
4535
3.06
265.98
1.6
1.4
—
—
—
0
0
4021
22120
2.27
265.37
2.2
1.7
—
—
—
0
0
1395
4662
3.03
264.67
1.6
1.4
—
—
—
0
0
4581
27070
2.22
246.86
4.5
3.6
—
—
—
0
0
3008
15884
2.11
204.58
1.7
1.9
—
—
—
0
0
4222
25923
1.98
182.04
2.0
2.1
—
—
—
0
0
581
1477
3.71
167.66
1.7
1.5
7.3
7.4
mmol/l
0.31
286
873
2291
11715
2.05
161.99
1.7
1.8
—
—
—
0
0
639
2103
2.86
119.96
2.0
2.1
4.3
4.7
umol/l
0.69
471
1518
5465
39235
1.79
116.07
4.1
3.6
531.2
1616.7
e6/l
2.33
59
416
534
1730
2.88
102.80
3.1
2.5
—
—
—
0
0
5466
40628
1.65
85.96
4.1
3.7
—
—
—
0
0
321
919
3.20
76.27
1.7
1.5
8.3
11.1
mmol/l
—
10
95
226
600
3.43
60.52
3.2
3.2
—
—
—
0
0
2931
32163
0.70
47.32
2.2
2.5
—
—
—
0
0
3972
29588
1.40
44.25
3.4
3.0
0.0
0.0
estimate
0.07
685
6105
3936
29385
1.39
42.59
4.8
4.1
0.0
0.0
estimate
2.81
695
6227
3886
29316
1.36
37.30
3.3
3.0
0.0
0.0
estimate
1.13
669
5988
163
480
3.07
36.99
3.2
3.0
—
—
—
0
0
175
588
2.69
31.31
1.3
1.3
—
—
—
0
0
987
12463
0.66
30.53
2.9
3.5
7.4
7.4
ph
1.02
171
2392
317
1414
2.04
29.63
4.5
6.9
—
—
—
0
0
3037
22649
1.32
28.70
3.1
2.8
—
6.1
—
0
7
157
527
2.69
28.18
1.3
1.3
—
—
—
0
0
2187
15637
1.34
27.40
2.3
2.2
—
—
—
0
0
1833
12843
1.35
26.02
3.2
3.0
—
—
—
0
0
256
1113
2.09
25.65
2.7
2.6
—
—
—
0
0
3525
27133
1.29
25.10
3.4
3.7
6.0
6.1
mmol/l
5.04
2729
24140
588
3339
1.62
24.62
3.1
2.3
—
—
—
0
0
1351
15621
0.72
24.59
2.4
2.8
2.3
2.3
mmol/l
0.22
1219
14142
128
418
2.76
24.27
2.0
2.5
6.7
6.9
mmol/l
0.26
128
408
1759
12380
1.34
23.92
3.3
3.1
1.0
1.0
kg/l
0.46
326
1779
137
474
2.60
23.24
1.6
1.4
5.0
5.0
mmol/l
0.07
129
452
4656
45524
0.78
23.22
3.2
3.6
35.9
36.4
mmol/mol
4.36
4408
43273
1670
18547
0.75
22.89
3.5
4.2
37.0
37.1
g/l
0.67
1560
17227
262
1241
1.91
20.68
1.6
1.5
6.1
6.5
mmol/l
1.69
176
848
63
147
3.84
20.59
1.0
1.1
—
—
—
0
0
349
1817
1.74
20.28
1.5
1.6
—
—
—
0
0
129
466
2.49
20.08
2.0
2.4
1.2
1.3
mmol/l
0.15
129
456
312
1578
1.79
20.02
1.5
2.6
3.6
3.6
g/l
0.07
298
1483
1012
11842
0.73
19.09
1.4
1.6
1.3
1.3
mmol/l
0.13
875
10490
556
7213
0.66
18.74
1.9
2.3
2.4
2.4
mmol/l
1.67
481
6243
1778
19152
0.78
18.41
2.4
2.9
27.2
27.5
u/l
0.09
1706
18300
1694
18292
0.78
17.74
3.7
4.5
1.2
1.2
mmol/l
1.63
1537
16695
7336
63246
1.51
17.73
8.5
8.6
—
—
—
0
0
1321
9271
1.32
17.64
2.3
2.2
6014.0
5663.4
u/l
0.16
691
3551
212
1007
1.90
16.66
1.4
1.3
—
—
—
0
0
1683
18051
0.78
16.38
4.9
5.7
—
—
—
0
0
2347
24224
0.81
16.21
2.1
2.2
74.1
72.7
nmol/l
1.87
2219
22831
91
314
2.60
15.66
1.2
1.2
—
—
—
0
0
76
247
2.76
14.71
2.3
2.2
—
—
—
0
0
3951
38489
0.83
14.51
5.4
6.2
69.4
69.1
u/l
0.22
3706
36230
222
1157
1.73
12.97
1.9
1.8
—
—
—
0
0
1992
20505
0.82
12.46
4.1
5.1
1.2
1.2
mmol/l
1.12
1723
17239
7697
67494
1.80
12.26
12.9
14.1
7.1
6.7
e9/l
42.44
7576
66121
7697
67500
1.80
12.16
13.0
14.1
130.8
133.2
g/l
69.63
7654
66904
1015
11227
0.78
12.15
1.7
2.0
106.1
143.0
u/l
3.33
974
10663
3363
32945
0.84
12.04
6.2
8.2
4.0
4.0
e9/l
0.10
2997
29231
1725
17957
0.82
11.98
1.6
1.7
100.4
98.7
pmol/l
0.89
1013
10071
7686
67397
1.75
11.82
12.9
14.0
259.7
272.5
e9/l
68.24
7571
66137
7692
67471
1.76
11.71
12.9
14.0
4.4
4.5
e12/l
50.45
7573
66150
7691
67461
1.76
11.69
12.8
13.9
29.9
29.9
pg
0.93
7650
66866
77
284
2.43
11.65
2.3
2.2
—
—
—
0
0
7691
67465
1.76
11.62
12.8
14.0
89.5
89.8
fl
6.08
7649
66873
529
6310
0.73
10.82
2.5
3.1
0.8
0.8
mmol/l
1.43
507
5907
557
6585
0.74
10.74
2.4
2.5
343.1
286.5
ng/l
0.16
202
2714
63
222
2.54
10.53
1.5
2.0
—
—
—
0
0
173
2564
0.59
10.48
2.7
2.7
—
—
—
0
0
20
33
5.41
9.97
1.3
1.3
—
—
—
0
0
1606
12257
1.21
9.91
1.5
1.5
—
—
—
0
0
385
4767
0.71
9.89
2.0
2.3
43.3
36.0
u/l
0.27
337
4050
500
5929
0.73
9.82
1.3
1.3
—
—
—
0
0
877
9644
0.79
9.81
1.4
1.4
20.6
20.7
nmol/l
0.09
788
8681
2665
26298
0.85
9.57
4.6
5.7
0.7
0.7
%
0.03
2478
24618
1289
13537
0.82
9.39
4.3
6.3
—
—
—
0
0
210
1178
1.60
9.38
2.2
3.1
24.9
25.1
mmol/l
0.32
204
1131
2962
28955
0.86
9.33
4.6
5.7
0.0
0.0
e9/l
0.00
2659
25730
2784
27330
0.86
9.24
4.6
5.6
2.7
2.7
%
0.26
2606
25586
3082
30022
0.86
9.23
4.6
5.9
0.2
0.2
e9/l
0.20
2808
27115
2955
28861
0.86
9.13
4.5
5.7
0.5
0.5
e9/l
5.35
2654
25720
92
1564
0.52
9.11
1.9
4.3
24.7
24.0
mmol/l
1.19
74
1390
2803
27468
0.86
9.01
4.7
5.8
7.5
7.7
%
3.71
2638
25963
376
4589
0.72
8.86
2.7
5.3
1.0
1.1
mmol/l
1.05
359
4331
339
2137
1.43
8.75
1.3
1.4
16.3
18.5
u/l
0.77
290
1768
2974
28962
0.86
8.67
4.5
5.5
30.1
30.2
%
0.50
2781
27292
4385
41536
0.87
8.66
3.2
3.6
8.4
8.8
mm/h
3.16
4131
39012
1087
11522
0.82
8.60
2.5
3.2
7.5
7.9
mmol/l
1.56
952
10055
505
5865
0.75
8.58
1.6
2.3
24.3
24.2
%
0.05
447
5044
36
849
0.38
8.51
5.4
5.6
347.6
373.8
umol/l
0.48
27
727
173
949
1.64
8.50
2.8
2.9
25.4
21.4
mg/l
0.85
103
537
1980
15602
1.18
8.32
3.4
3.2
0.0
0.0
estimate
0.93
685
6143
449
5277
0.74
8.29
1.9
2.1
—
—
—
0
0
3131
30315
0.87
8.27
4.5
5.6
1.9
2.0
e9/l
2.80
2867
27526
5927
54815
0.85
8.08
6.5
8.5
3.9
3.9
mmol/l
6.64
5708
53013
500
5760
0.76
8.01
1.8
2.0
—
—
—
0
0
2227
17764
1.16
7.95
3.0
2.6
—
—
—
0
0
137
2001
0.60
7.91
3.9
5.7
24.2
24.3
mmol/l
0.05
137
1989
275
3466
0.70
7.85
2.2
2.3
0.2
0.2
g/l
0.15
261
3256
2948
28575
0.87
7.71
4.4
5.4
56.8
56.3
%
1.66
2768
27028
500
5727
0.76
7.68
1.8
2.1
—
—
—
0
0
505
5772
0.76
7.63
1.8
2.1
—
—
—
0
0
338
4095
0.72
7.63
2.1
2.8
—
—
—
0
0
6563
60125
0.83
7.62
7.5
9.2
63.8
65.3
umol/l
18.30
6558
60090
2620
25562
0.87
7.45
6.5
7.6
0.0
0.0
e9/l
5.21
2185
20934
498
5674
0.77
7.34
1.6
2.0
—
—
—
0
0
5922
54663
0.86
7.25
6.5
8.4
139.4
139.4
mmol/l
1.44
5725
52982
5894
54420
0.86
7.23
2.8
3.2
2.8
2.9
mmol/l
3.41
5623
51740
376
2497
1.36
7.19
1.7
1.6
—
—
—
0
0
4557
42688
0.88
6.44
2.3
2.6
27.3
29.3
u/l
1.82
4405
40967
193
2482
0.69
6.22
3.5
7.5
5.5
6.5
mmol/l
2.92
181
2394
5871
54038
0.87
5.96
2.7
3.1
4.7
4.8
mmol/l
6.04
5625
51774
599
6483
0.81
5.71
1.7
1.7
1132.7
1183.4
nmol/l
0.71
482
5090
205
1280
1.44
5.71
2.3
3.0
0.2
0.3
g/l
2.28
76
529
609
6564
0.81
5.58
1.1
1.2
—
—
—
0
0
397
4492
0.78
5.58
1.9
2.2
—
—
—
0
0
2464
23814
0.89
5.58
4.2
4.8
9.8
9.4
umol/l
1.03
2307
22172
1157
11766
0.86
5.54
2.5
3.2
99.2
98.7
%
0.35
1118
11373
702
7453
0.82
5.53
1.2
1.3
19.3
20.8
iu/l
0.71
630
6350
303
3548
0.75
5.51
1.3
1.3
—
—
—
0
0
208
2577
0.71
5.47
2.4
3.6
56.6
73.7
ng/l
5.31
191
2326
5846
53735
0.88
5.41
2.7
3.0
1.5
1.5
mmol/l
0.92
5605
51408
220
2692
0.72
5.37
4.4
6.2
1.4
1.3
mmol/l
1.03
211
2597
199
2465
0.71
5.24
4.9
7.9
—
—
—
0
0
99
1406
0.62
5.22
6.4
8.9
24.2
23.9
mmol/l
0.58
93
1324
84
1237
0.60
5.16
1.2
1.3
313.5
317.6
ug/g
0.06
29
610
41
741
0.49
5.09
1.3
1.6
41.3
39.5
g/l
2.44
36
672
259
3058
0.75
5.02
5.3
6.7
0.6
0.6
mmol/l
0.05
181
2247
338
3846
0.77
4.99
3.7
3.9
0.5
0.5
%
0.04
57
646
36
674
0.47
4.96
1.9
2.9
—
—
—
0
0
624
6630
0.82
4.95
1.5
2.2
2.6
2.5
g/l
3.45
576
6126
258
3038
0.75
4.92
5.2
6.7
14.2
14.3
kpa
0.06
244
2903
258
3037
0.75
4.90
5.2
6.7
4.8
5.0
kpa
2.41
246
2904
5
212
0.21
4.87
45.4
38.4
7.8
7.5
ug/l
—
5
200
269
3133
0.76
4.75
8.3
9.3
1.1
1.1
inr
0.38
59
577
1015
10307
0.86
4.72
2.6
2.4
84.3
92.0
ug/g
0.43
784
7937
198
2408
0.73
4.69
1.2
1.3
—
—
—
0
0
546
5845
0.82
4.69
3.2
3.2
—
—
—
0
0
711
7414
0.84
4.60
1.6
2.2
15.5
14.8
umol/l
1.46
667
6873
1106
8695
1.16
4.55
2.5
2.4
543.8
528.2
mosm/kgh2o
1.27
907
7351
503
5399
0.82
4.45
1.3
1.3
—
—
—
0
0
344
3845
0.79
4.42
4.0
4.3
0.0
0.2
%
0.39
66
693
1605
15731
0.89
4.39
3.6
3.8
—
—
—
0
0
5657
51917
0.90
4.37
2.7
3.1
5.4
5.5
mmol/l
10.58
5324
48983
943
7359
1.16
4.28
1.3
1.2
132.9
153.9
iu/ml
1.01
372
2864
113
1486
0.67
4.22
1.2
1.3
—
—
—
0
0
293
3319
0.78
4.22
2.8
3.0
1.2
1.2
mmol/l
0.02
257
2838
211
1401
1.35
4.20
1.3
1.2
—
—
—
0
0
136
1725
0.70
4.18
1.6
1.9
4.6
5.3
ug/l
0.23
112
1493
1365
13460
0.88
4.10
3.9
4.3
1.0
1.1
inr
0.05
435
4918
1469
11854
1.13
4.07
1.6
1.7
—
—
—
0
0
520
5512
0.83
4.05
2.0
2.3
5.2
5.6
umol/l
0.53
439
4530
23
81
2.54
4.04
1.2
1.1
—
—
—
0
0
67
970
0.61
3.93
1.6
1.5
—
—
—
0
0
573
5984
0.84
3.79
1.8
2.0
384.2
384.3
nmol/l
0.00
534
5503
6265
57063
0.89
3.79
4.9
4.9
1.6
1.9
mu/l
3.61
5984
54492
127
1599
0.70
3.79
1.7
2.2
13.0
13.1
%
0.61
127
1579
784
7975
0.86
3.73
2.6
3.4
278.4
485.2
mg/l
0.79
511
4994
4228
36134
1.09
3.67
3.0
3.0
52.4
58.0
ug/l
1.74
4022
34511
6
195
0.27
3.64
1.5
1.6
—
—
—
0
0
45
704
0.57
3.61
1.1
1.1
—
—
—
0
0
217
2498
0.77
3.60
5.8
7.4
121.1
122.0
g/l
0.27
209
2404
123
1538
0.71
3.55
1.1
1.2
239.3
251.6
u/ml
0.20
84
1030
54
279
1.73
3.55
1.9
1.6
2.2
2.1
u/field
0.05
26
163
39
630
0.55
3.51
1.2
1.3
—
—
—
0
0
84
1125
0.66
3.51
1.1
1.1
—
—
—
0
0
121
1514
0.71
3.51
7.1
8.3
—
—
—
0
0
819
8268
0.87
3.50
3.2
4.2
13.0
11.3
mg/mmol
0.40
548
5286
212
2431
0.77
3.43
1.6
1.8
—
—
—
0
0
1205
11851
0.89
3.43
1.3
1.3
20.5
22.9
iu/ml
0.43
368
3573
480
3615
1.20
3.39
2.7
3.1
—
—
—
0
0
147
1771
0.73
3.38
1.8
2.3
50.9
80.2
ng/l
2.68
123
1559
116
1451
0.71
3.37
1.4
1.3
26.1
3586.0
e6/l
0.80
95
1184
116
1450
0.71
3.36
1.3
1.3
19.6
19.3
e6/l
0.02
89
1133
1911
18316
0.91
3.34
1.3
1.3
1.3
1.4
u/ml
0.25
568
5336
13
37
3.13
3.34
9.1
5.4
—
—
—
0
0
6759
61213
0.89
3.33
6.7
7.8
22.7
23.2
u/l
0.76
6553
59473
387
4135
0.83
3.33
3.8
4.2
0.9
0.8
%
0.35
92
872
28
491
0.51
3.31
1.3
1.6
92.2
91.6
%
0.32
28
485
287
3158
0.80
3.29
1.9
1.8
1.4
1.3
g/l
0.07
267
2948
5632
51475
0.91
3.28
2.5
2.8
1.1
1.1
mmol/l
16.90
5411
49221
6756
59188
1.12
3.15
8.2
9.3
18.1
17.8
mg/l
0.40
5336
44229
1584
15283
0.90
3.15
1.4
1.4
2.0
2.0
g/l
0.01
1022
9803
375
3990
0.83
3.10
3.9
4.2
0.2
0.2
%
0.20
85
820
232
2593
0.79
3.08
5.4
7.2
97.7
96.5
%
5.93
222
2488
215
1503
1.28
3.07
1.4
1.4
30.5
32.7
nmol/l
0.60
199
1401
44
660
0.59
3.07
1.3
1.3
—
—
—
0
0
133
1600
0.74
3.07
6.3
8.7
96.0
94.3
%
10.33
133
1592
11
269
0.36
3.06
2.0
2.6
11.1
11.1
%
0.01
11
269
118
1442
0.73
3.02
1.2
1.2
3.5
3.5
mmol/l
0.03
110
1345
70
406
1.54
2.98
1.5
1.5
—
—
—
0
0
133
1591
0.74
2.97
2.1
1.8
—
—
—
0
0
42
626
0.60
2.88
1.5
1.5
347.0
472.3
pmol/l
1.04
27
503
75
982
0.68
2.86
2.0
2.7
7.4
7.4
ph
0.78
64
845
401
4205
0.84
2.84
2.4
2.5
10.8
10.5
g/l
1.45
366
3874
20
369
0.48
2.81
1.2
1.3
—
—
—
0
0
281
2051
1.23
2.80
2.2
2.1
3.5
13.8
iu/l
0.85
119
893
64
858
0.66
2.77
2.2
2.7
8.9
9.2
kpa
1.17
64
846
15
306
0.44
2.77
7.7
6.8
10.3
10.7
mg/l
0.12
15
288
64
857
0.66
2.75
2.2
2.7
4.9
5.0
kpa
0.31
64
845
64
857
0.66
2.75
2.2
2.7
2.6
2.1
mmol/l
0.69
31
481
714
7152
0.88
2.75
1.2
1.2
—
—
—
0
0
963
9467
0.89
2.71
1.4
1.4
663.9
564.8
titre
0.67
191
1846
44
637
0.61
2.70
3.3
2.9
29.4
32.1
umol/l
0.52
37
539
252
2746
0.81
2.70
1.1
1.1
—
—
—
0
0
1161
11295
0.90
2.70
1.3
1.3
6.4
9.1
u/ml
1.22
518
4764
203
2254
0.80
2.60
2.1
2.0
1.2
1.2
g/l
0.09
195
2146
967
9459
0.90
2.49
1.5
1.5
171312836.9
26503681.1
pmol/l
3.70
861
8282
77
973
0.70
2.47
1.8
2.1
217.2
287.1
ug/l
0.27
65
822
303
3209
0.84
2.45
1.1
1.1
88.9
4.8
u/ml
—
5
45
5610
51080
0.93
2.44
4.4
4.3
14.2
14.2
pmol/l
0.56
5292
47953
182
2023
0.80
2.38
1.1
1.1
—
—
—
0
0
55
734
0.67
2.38
1.4
2.1
17.3
17.2
%
0.11
31
366
144
1637
0.78
2.29
1.2
1.3
458.3
400.5
mg/l
0.77
136
1557
12
245
0.44
2.27
1.0
1.1
5.5
4.6
mg/g
0.68
12
234
67
411
1.46
2.27
2.0
2.3
—
—
—
0
0
6
155
0.34
2.27
1.0
1.0
—
—
—
0
0
744
5975
1.12
2.27
1.5
1.6
—
—
—
0
0
120
1394
0.76
2.26
1.3
1.3
2312.0
837.7
titre
—
5
48
14
269
0.46
2.26
3.6
2.5
41.1
45.5
%
—
7
103
19
326
0.52
2.21
2.1
2.6
90.3
182.7
umol/l
—
10
154
84
1023
0.73
2.20
1.0
1.1
—
—
—
0
0
204
2217
0.82
2.19
1.8
2.4
71.9
71.1
e9/l
0.10
149
1572
52
686
0.67
2.15
1.3
1.4
—
—
—
0
0
6
149
0.36
2.15
1.2
1.2
—
—
—
0
0
46
621
0.66
2.14
1.0
1.1
1.5
1.5
g/l
0.36
41
572
55
329
1.49
2.13
1.2
1.2
—
—
—
0
0
202
2189
0.82
2.12
2.2
2.1
0.2
0.2
g/l
0.05
193
2078
39
544
0.64
2.12
3.5
2.8
37.7
23.9
mg/l
0.45
30
443
64
809
0.70
2.11
2.4
2.7
24.5
23.8
mmol/l
1.27
56
714
37
521
0.63
2.10
3.5
2.8
0.9
1.4
ratio
—
5
72
1041
10053
0.91
2.09
1.2
1.2
—
—
—
0
0
39
542
0.64
2.09
3.5
2.8
22.6
42.2
mg/l
1.58
29
441
56
723
0.69
2.08
1.4
1.7
—
—
—
0
0
173
1246
1.24
2.04
1.2
1.3
4.0
4.1
u/ml
0.04
77
540
46
613
0.67
2.03
1.7
1.8
22.0
21.2
nmol/l
0.25
46
588
11
220
0.44
2.01
1.1
1.2
—
0.2
—
0
9
434
4384
0.88
1.96
1.2
1.2
—
—
—
0
0
14
252
0.49
1.93
1.0
1.1
—
—
—
0
0
34
476
0.63
1.91
1.3
1.5
1.3
1.2
promille
0.25
27
368
15
63
2.12
1.90
2.1
2.0
—
—
—
0
0
469
3709
1.13
1.88
1.2
1.2
3.5
3.3
ug/l
0.32
443
3484
336
3441
0.86
1.87
2.4
2.6
1.7
1.6
%
0.31
300
3037
14
245
0.51
1.79
3.6
3.0
—
—
—
0
0
18
84
1.91
1.75
1.1
1.1
0.1
2.2
u/ml
—
9
33
115
1292
0.79
1.74
2.3
2.4
—
—
—
0
0
9
32
2.51
1.72
1.1
1.0
—
—
—
0
0
304
3112
0.87
1.70
1.3
1.3
—
—
—
0
0
123
1366
0.80
1.69
1.3
1.3
—
—
—
0
0
71
844
0.75
1.67
1.8
2.6
—
—
—
0
0
397
3138
1.13
1.64
2.7
3.2
—
—
—
0
0
590
5783
0.90
1.64
1.3
1.4
—
—
—
0
0
41
532
0.69
1.63
4.1
2.6
—
—
—
0
0
100
1132
0.78
1.63
4.0
4.3
1.0
1.2
mmol/l
2.94
84
1021
260
2677
0.86
1.60
1.5
1.5
0.5
0.5
nmol/l
0.69
228
2213
24
347
0.62
1.59
2.2
1.5
—
—
—
0
0
2120
18076
1.06
1.58
3.1
3.1
60.5
66.9
e6/l
0.26
1256
11272
66
785
0.75
1.57
1.0
1.1
223.5
191.5
mg/l
0.62
59
681
130
1421
0.81
1.57
1.1
1.0
0.3
0.2
u/ml
0.05
25
263
130
1418
0.81
1.54
1.3
1.3
97.1
147.0
titre
—
7
149
2635
24354
0.95
1.54
1.8
1.9
—
—
—
0
0
0
38
0.00
1.53
0.0
1.4
—
27.4
—
0
38
660
6407
0.91
1.53
1.8
1.6
—
—
—
0
0
164
1218
1.20
1.52
1.1
1.2
—
—
—
0
0
84
960
0.78
1.51
1.7
1.6
0.5
0.6
g/l
1.08
65
715
148
1588
0.83
1.50
4.0
4.3
—
—
—
0
0
0
41
0.00
1.50
0.0
1.5
—
173.4
—
0
34
12
206
0.52
1.49
3.0
2.9
—
—
—
0
0
34
444
0.68
1.44
2.3
2.6
2.5
15.6
nmol/l
0.53
34
424
38
483
0.70
1.40
1.4
1.5
—
—
—
0
0
38
483
0.70
1.40
1.4
1.5
—
—
—
0
0
475
4660
0.90
1.38
2.2
2.5
26.9
34.9
u/ml
2.39
462
4519
38
482
0.70
1.38
1.4
1.5
—
—
—
0
0
38
482
0.70
1.38
1.4
1.5
—
—
—
0
0
70
808
0.77
1.38
1.1
1.2
35.8
34.4
mg/l
0.10
58
662
71
486
1.30
1.36
1.2
1.2
1.4
12.5
u/ml
—
9
59
297
2987
0.88
1.34
1.7
1.7
—
—
—
0
0
198
2047
0.86
1.33
1.1
1.1
1.2
2.9
u/ml
2.10
47
502
79
893
0.79
1.33
3.0
3.8
18.0
27.1
u/ml
2.27
74
856
154
1625
0.84
1.33
6.0
5.8
24.0
24.1
mmol/l
0.19
145
1507
171
1294
1.18
1.33
1.9
2.0
1.1
1.3
g/l
2.14
149
1138
7
134
0.47
1.32
1.7
1.1
—
—
—
0
0
7
134
0.47
1.32
1.7
1.1
—
—
—
0
0
7
134
0.47
1.32
1.7
1.1
—
—
—
0
0
277
2177
1.14
1.31
1.5
2.0
20.6
20.6
s
0.01
234
1766
119
872
1.22
1.31
2.3
2.3
—
—
—
0
0
14
219
0.57
1.30
1.3
1.5
—
—
—
0
0
8
30
2.38
1.29
1.0
1.0
—
—
—
0
0
25
143
1.56
1.28
1.2
1.4
—
—
—
0
0
31
401
0.69
1.28
1.3
1.6
79.5
68.9
mmol/l
0.41
24
311
60
696
0.77
1.25
1.4
1.3
—
—
—
0
0
34
430
0.70
1.24
1.1
1.2
264.3
196.3
titre
—
7
82
34
430
0.70
1.24
1.1
1.2
—
57.5
—
0
12
39
247
1.41
1.24
1.5
1.4
1.2
2.0
u/field
0.52
27
186
196
2013
0.86
1.23
1.2
1.2
—
—
—
0
0
11
181
0.54
1.23
1.7
2.9
—
—
—
0
0
20
280
0.64
1.22
4.1
3.0
104.2
120.2
mg/l
0.11
15
197
52
611
0.76
1.20
1.1
1.2
—
—
—
0
0
299
2980
0.89
1.20
1.3
1.3
0.7
0.9
u/ml
0.14
41
205
370
3644
0.90
1.20
4.2
6.3
105.5
105.1
mmol/l
1.38
362
3577
639
6134
0.92
1.19
1.4
1.6
256.1
332.7
mu/l
14.47
579
5437
19
267
0.63
1.18
2.1
2.1
2.1
1.0
ug/l
0.80
19
250
0
30
0.00
1.17
0.0
1.1
—
115.4
—
0
30
172
1775
0.86
1.17
1.1
1.1
2.8
5.5
u/ml
1.66
73
674
0
31
0.00
1.16
0.0
1.9
—
—
—
0
0
176
1811
0.86
1.15
1.9
2.6
5.0
5.0
kpa
0.49
155
1696
14
210
0.59
1.14
1.1
1.3
—
—
—
0
0
65
453
1.28
1.14
1.0
1.0
—
—
—
0
0
463
4493
0.91
1.12
2.3
2.3
20.0
21.9
au/ml
0.26
30
370
60
415
1.29
1.11
2.3
4.4
5.9
6.8
mmol/l
1.09
48
335
85
614
1.24
1.11
1.2
1.2
—
—
—
0
0
60
681
0.78
1.09
1.8
1.3
—
—
—
0
0
174
1783
0.87
1.09
1.9
2.6
7.4
7.4
ph
1.39
22
283
33
408
0.72
1.09
3.8
3.0
—
—
—
0
0
651
5408
1.08
1.09
1.5
2.1
28.5
29.2
s
4.05
621
5216
62
700
0.79
1.08
1.0
1.0
0.2
0.4
u/ml
—
7
100
79
865
0.81
1.06
3.1
3.3
261.3
291.2
u/ml
0.04
64
749
5
19
2.35
1.06
1.0
1.1
—
—
—
0
0
5
19
2.35
1.06
1.0
1.1
—
—
—
0
0
20
268
0.66
1.03
1.1
1.1
—
—
—
0
0
188
1469
1.14
1.03
1.1
1.1
2.3
2.6
u/ml
0.36
92
855
433
4188
0.92
1.00
1.2
1.3
30.6
37.2
au/ml
0.23
13
155
7
31
2.01
1.00
1.0
1.0
—
—
—
0
0
0
27
0.00
0.98
0.0
1.2
—
—
—
0
0
29
357
0.72
0.96
1.6
1.8
—
—
—
0
0
163
1659
0.87
0.96
1.1
1.1
4.5
6.0
u/ml
0.60
72
682
682
5708
1.07
0.96
1.3
1.3
—
—
—
0
0
279
2748
0.90
0.95
3.1
3.5
9.2
27.4
ug/l
0.64
189
1860
60
666
0.80
0.94
1.8
1.4
—
—
—
0
0
40
467
0.76
0.94
1.1
1.1
—
—
—
0
0
125
956
1.17
0.93
1.4
1.4
—
—
—
0
0
335
3263
0.91
0.92
1.2
1.2
—
—
—
0
0
12
62
1.73
0.92
1.0
6.0
—
—
—
0
0
450
4326
0.92
0.92
1.2
1.2
—
—
—
0
0
25
156
1.43
0.91
1.0
1.1
—
—
—
0
0
32
209
1.37
0.91
2.2
2.1
—
—
—
0
0
60
661
0.81
0.89
1.7
1.4
6.5
6.4
g/l
0.14
42
461
241
2381
0.90
0.89
1.4
1.5
65.0
84.1
pmol/l
0.55
234
2316
51
572
0.79
0.89
1.8
2.2
—
—
—
0
0
60
660
0.81
0.88
1.7
1.4
3.1
2.9
g/l
0.52
41
463
60
660
0.81
0.88
1.7
1.4
0.4
0.3
g/l
1.38
41
463
382
3687
0.92
0.87
1.1
1.1
—
—
—
0
0
42
481
0.78
0.87
2.3
2.9
—
30.4
—
0
5
285
2777
0.91
0.82
1.7
1.6
—
—
—
0
0
45
506
0.79
0.82
1.4
1.4
—
—
—
0
0
151
1188
1.14
0.80
1.1
1.1
119.0
118.0
%
0.18
139
1077
13
179
0.65
0.80
2.2
1.8
—
—
—
0
0
8
42
1.70
0.80
1.0
1.1
—
—
—
0
0
8
42
1.70
0.80
3.4
2.5
—
—
—
0
0
6
29
1.84
0.80
5.3
4.2
—
—
—
0
0
0
22
0.00
0.79
0.0
1.0
—
—
—
0
0
0
24
0.00
0.78
0.0
1.0
—
0.1
—
0
12
7
110
0.57
0.78
1.9
1.5
—
—
—
0
0
219
2155
0.90
0.78
2.0
2.0
67.9
67.7
g/l
0.17
204
2001
12
167
0.64
0.78
1.6
1.6
17.3
17.1
umol/l
0.07
12
148
5
89
0.50
0.78
4.4
2.1
—
—
—
0
0
118
918
1.15
0.75
1.1
1.1
3375.7
10045.3
iu/ml
0.31
23
247
8
118
0.60
0.74
1.4
1.5
—
—
—
0
0
5
22
2.03
0.73
1.0
1.0
—
—
—
0
0
6
99
0.54
0.72
2.0
1.7
5.3
485721.3
nmol/l
—
6
77
85
648
1.17
0.71
1.0
1.1
—
—
—
0
0
5
23
1.94
0.71
2.0
1.9
—
—
—
0
0
688
6445
0.95
0.70
1.2
1.2
—
—
—
0
0
181
1455
1.11
0.70
1.2
1.3
—
—
—
0
0
40
283
1.26
0.70
1.0
1.1
—
—
—
0
0
23
150
1.37
0.69
1.3
3.9
52.4
3959.5
mg/l
1.08
11
106
6681
59157
1.04
0.68
8.8
10.1
38.4
39.7
%
37.06
5541
50048
40
284
1.26
0.68
1.1
1.1
—
—
—
0
0
7
38
1.64
0.67
1.1
1.0
—
—
—
0
0
10
139
0.64
0.66
1.2
1.3
85.1
114.9
nmol/l
—
10
106
249
2041
1.09
0.66
2.8
2.4
0.2
0.2
e6/l
0.41
238
1941
11
149
0.66
0.65
1.2
1.1
—
—
—
0
0
44
480
0.82
0.65
1.1
1.4
—
—
—
0
0
18
114
1.41
0.65
1.1
1.1
—
—
—
0
0
8
117
0.61
0.63
1.4
1.4
—
—
—
0
0
5
26
1.71
0.63
3.0
3.2
—
—
—
0
0
46
496
0.83
0.62
1.3
1.2
—
—
—
0
0
8
45
1.58
0.61
1.3
2.8
—
—
—
0
0
0
18
0.00
0.61
0.0
1.1
—
—
—
0
0
0
18
0.00
0.61
0.0
31.4
—
—
—
0
0
9
124
0.65
0.61
1.1
1.4
—
—
—
0
0
32
358
0.80
0.60
2.3
2.7
—
—
—
0
0
5
27
1.65
0.60
3.0
3.1
—
—
—
0
0
0
19
0.00
0.60
0.0
1.0
—
—
—
0
0
0
19
0.00
0.60
0.0
1.4
—
51.5
—
0
11
5923
53199
0.97
0.60
9.7
11.3
13.3
13.4
%
0.58
5839
52148
25
288
0.77
0.60
1.6
1.5
129.5
130.2
nmol/l
0.04
25
288
245
2358
0.92
0.59
1.1
1.1
1.5
1.2
u/ml
0.28
104
885
42
307
1.22
0.58
1.8
1.7
52.3
44.7
%
0.56
26
182
0
21
0.00
0.58
0.0
1.3
—
3.2
—
0
21
27
306
0.79
0.57
2.2
2.6
—
—
—
0
0
179
1461
1.09
0.55
1.2
1.3
10.3
22.6
u/ml
—
7
28
90
907
0.88
0.54
1.6
2.5
—
—
—
0
0
14
88
1.42
0.54
1.3
1.1
—
—
—
0
0
58
442
1.17
0.53
1.3
1.3
41.8
41.2
u/ml
—
6
22
46
487
0.84
0.53
1.2
1.2
—
—
—
0
0
9
55
1.46
0.53
1.0
1.1
—
—
—
0
0
1580
13731
1.03
0.53
2.7
2.7
41.6
78.4
e6/l
1.64
1127
10109
9
118
0.68
0.52
1.2
1.2
—
—
—
0
0
65
503
1.15
0.50
1.1
1.1
6.7
7.7
iu/ml
0.20
21
157
170
1393
1.09
0.50
1.2
1.3
112.1
106.7
u/ml
0.10
55
323
21
240
0.78
0.49
1.2
2.0
—
—
—
0
0
125
1226
0.91
0.49
1.3
1.2
—
—
—
0
0
24
269
0.79
0.49
1.2
1.1
—
—
—
0
0
7
96
0.65
0.49
1.3
1.4
—
—
—
0
0
1497
13020
1.03
0.48
1.6
1.7
1.1
0.8
mg/l
2.07
1140
9279
77
606
1.13
0.48
1.2
1.1
1.1
1.0
ratio
0.17
20
249
75
755
0.88
0.47
1.0
1.0
—
—
—
0
0
785
6761
1.04
0.46
2.4
2.4
4.8
5.5
e6/l
1.02
438
3262
32
344
0.83
0.45
3.0
2.9
9.8
8.2
mg/l
0.66
21
269
49
375
1.17
0.45
1.1
1.1
13.5
11.1
u/ml
0.15
11
70
1152
9993
1.03
0.45
2.4
2.4
—
—
—
0
0
10
126
0.71
0.45
2.5
2.7
—
—
—
0
0
7
45
1.39
0.44
1.4
1.2
—
—
—
0
0
72
723
0.89
0.44
3.7
3.6
3.8
3.7
mmol/l
0.31
66
668
23
163
1.26
0.44
1.2
1.1
—
—
—
0
0
468
4357
0.95
0.44
2.0
2.2
4.2
4.1
e9/l
0.19
377
3731
149
1225
1.09
0.43
2.1
2.9
0.7
0.7
%
0.56
141
1171
819
7070
1.04
0.43
2.4
2.3
1.3
1.1
e6/l
0.16
472
3565
223
2119
0.94
0.43
1.1
1.1
6.6
6.1
u/ml
0.20
109
1115
1514
13201
1.03
0.42
2.0
2.3
16.4
23.1
ng/l
1.15
510
4335
20
224
0.80
0.42
1.2
1.2
—
—
—
0
0
42
436
0.86
0.42
1.1
1.1
—
—
—
0
0
0
14
0.00
0.41
0.0
1.0
—
—
—
0
0
14
164
0.76
0.41
1.1
1.1
—
—
—
0
0
177
1692
0.93
0.41
1.2
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.4
—
210.5
—
0
15
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
0
15
0.00
0.41
0.0
6.1
—
436.6
—
0
15
0
15
0.00
0.41
0.0
1.6
—
—
—
0
0
0
16
0.00
0.40
0.0
1.1
—
—
—
0
0
0
16
0.00
0.40
0.0
1.1
—
—
—
0
0
35
367
0.85
0.40
1.1
1.1
0.1
4.7
nmol/l
—
10
64
59
464
1.13
0.39
1.2
1.2
—
—
—
0
0
5
31
1.44
0.39
3.0
2.6
—
—
—
0
0
0
17
0.00
0.39
0.0
1.1
—
—
—
0
0
55
431
1.14
0.39
1.1
1.1
1411.1
1502.0
miu/ml
0.25
55
431
11
71
1.38
0.38
1.0
1.1
—
—
—
0
0
39
403
0.86
0.38
1.1
1.2
—
—
—
0
0
9
62
1.29
0.37
1.0
1.1
—
—
—
0
0
210
1985
0.94
0.37
1.1
1.1
1.4
1.1
u/ml
0.40
84
821
43
333
1.15
0.36
1.1
1.1
3.0
2.6
u/ml
0.05
18
202
29
306
0.84
0.36
2.6
2.1
10.0
8.1
%
0.57
29
290
39
400
0.87
0.35
1.1
1.1
—
—
—
0
0
60
597
0.89
0.34
2.2
2.7
25.3
110.7
ug/min
3.48
45
390
22
237
0.83
0.34
1.3
1.1
—
—
—
0
0
22
237
0.83
0.34
1.6
1.7
—
—
—
0
0
14
159
0.78
0.34
1.1
1.2
—
—
—
0
0
20
145
1.23
0.34
1.1
1.0
—
—
—
0
0
80
782
0.91
0.34
2.1
3.8
0.8
0.9
nmol/l
0.28
64
673
76
615
1.10
0.33
1.0
1.0
—
—
—
0
0
6
41
1.30
0.33
1.5
1.2
—
—
—
0
0
21
225
0.83
0.32
2.1
2.0
1995.2
1955.0
ml
0.06
21
210
198
1863
0.95
0.31
2.2
2.1
—
—
—
0
0
210
1776
1.06
0.31
1.3
1.3
24.6
8.4
u/ml
0.35
23
195
23
172
1.19
0.30
1.0
1.1
—
—
—
0
0
23
172
1.19
0.30
1.0
1.1
—
—
—
0
0
23
172
1.19
0.30
1.0
1.1
—
—
—
0
0
52
516
0.90
0.30
2.1
2.0
16.5
5.8
u/ml
0.77
38
417
24
252
0.85
0.30
1.1
1.3
—
—
—
0
0
1421
12449
1.02
0.29
2.6
2.6
0.2
0.3
e6/l
1.74
994
8982
92
758
1.08
0.29
1.3
1.4
—
—
—
0
0
10
116
0.77
0.29
2.6
2.4
—
—
—
0
0
10
116
0.77
0.29
1.2
1.6
—
—
—
0
0
28
288
0.87
0.28
2.4
2.0
32.2
27.3
%
1.29
28
277
53
522
0.90
0.28
1.1
1.2
1.7
1.8
mmol/l
0.20
46
492
34
344
0.88
0.27
1.3
1.2
—
—
—
0
0
43
342
1.12
0.27
2.2
2.8
—
—
—
0
0
979
8901
0.98
0.27
3.0
3.6
—
—
—
0
0
34
267
1.14
0.26
1.4
1.4
12.5
13.4
pmol/l
0.87
28
226
6200
55047
1.02
0.26
10.0
11.7
332.7
332.1
g/l
5.83
6165
54621
39
389
0.89
0.26
8.3
7.3
—
—
—
0
0
72
592
1.08
0.25
2.6
2.3
1.4
1.3
e9/l
0.24
39
351
9
65
1.23
0.25
1.8
1.6
—
—
—
0
0
196
1826
0.96
0.24
1.1
1.1
—
—
—
0
0
76
729
0.93
0.24
1.1
1.0
0.3
3.6
u/ml
1.62
11
167
11
122
0.80
0.24
1.9
1.9
—
—
—
0
0
77
738
0.93
0.24
1.5
1.6
5378.1
7773.5
e6/l
0.75
57
541
13
94
1.23
0.23
1.3
1.1
—
—
—
0
0
25
255
0.87
0.23
2.4
2.2
—
—
—
0
0
1197
10504
1.02
0.23
1.9
2.0
3086.4
2259.4
umol/l
0.44
1079
9485
7
84
0.74
0.22
2.6
2.0
1.2
1.3
umol/l
—
7
78
7
84
0.74
0.22
1.0
1.1
—
—
—
0
0
1568
13798
1.02
0.22
1.9
2.1
2.6
2.6
mg/l
0.39
1324
11866
0
9
0.00
0.21
0.0
1.0
—
—
—
0
0
0
9
0.00
0.21
0.0
1.0
—
—
—
0
0
0
9
0.00
0.21
0.0
1.0
—
—
—
0
0
0
9
0.00
0.21
0.0
1.7
—
371.5
—
0
9
0
9
0.00
0.21
0.0
2.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
395.2
—
0
10
568
5177
0.98
0.21
1.2
1.3
171.7
197.1
u/ml
0.31
529
4798
609
5312
1.02
0.21
3.5
3.4
4.6
4.6
pmol/l
0.03
557
4797
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
2.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
121.3
—
0
11
0
11
0.00
0.21
0.0
2.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.0
—
—
—
0
0
20
154
1.16
0.20
3.0
1.7
—
—
—
0
0
10
71
1.26
0.20
1.2
1.1
—
—
—
0
0
0
12
0.00
0.20
0.0
1.2
—
35.6
—
0
12
0
12
0.00
0.20
0.0
1.3
—
—
—
0
0
16
121
1.18
0.20
1.3
1.8
—
—
—
0
0
9
99
0.81
0.20
1.1
1.3
—
—
—
0
0
0
13
0.00
0.20
0.0
3.3
—
—
—
0
0
2631
23260
1.01
0.19
2.0
2.0
—
—
—
0
0
65
620
0.93
0.19
1.7
1.5
—
—
—
0
0
160
1368
1.04
0.19
1.1
1.1
17.9
11.9
au/ml
0.34
14
100
210
1806
1.04
0.19
1.3
1.3
10.4
12.0
u/ml
0.12
40
286
40
389
0.92
0.18
2.4
2.6
903.8
914.7
e6/l
0.03
24
171
177
1638
0.96
0.18
1.1
1.1
—
—
—
0
0
65
542
1.07
0.18
2.4
2.5
1.4
1.2
%
0.26
49
409
177
1637
0.96
0.18
1.1
1.1
—
—
—
0
0
44
425
0.92
0.18
1.1
1.1
—
—
—
0
0
13
136
0.85
0.17
1.1
1.1
—
—
—
0
0
5
60
0.74
0.17
3.6
2.3
—
—
—
0
0
188
1619
1.04
0.17
1.3
1.3
46.8
42.9
u/ml
0.08
17
164
80
753
0.95
0.17
4.9
4.4
104.2
106.2
u/ml
0.02
35
250
1678
15098
0.99
0.16
2.2
2.4
55.2
56.3
u/l
0.32
1583
13944
466
4234
0.98
0.15
1.1
1.1
67.8
204.8
titre
—
9
102
229
1985
1.03
0.15
1.3
1.3
48.4
37.5
u/ml
0.21
19
141
58
487
1.06
0.14
2.3
2.0
8.9
12.7
%
3.22
27
272
14
108
1.16
0.14
3.1
3.3
0.8
0.8
nmol/l
—
8
76
10
105
0.85
0.14
1.0
1.2
—
—
—
0
0
38
315
1.08
0.13
1.1
1.1
—
—
—
0
0
542
4901
0.98
0.12
1.3
1.3
233.8
235.8
miu/ml
0.05
295
2571
49
413
1.06
0.11
1.7
1.7
42.2
45.6
%
0.23
31
255
22
214
0.92
0.11
1.0
1.0
—
—
—
0
0
846
7614
0.99
0.10
1.5
1.5
—
—
—
0
0
16
158
0.90
0.10
1.0
2.1
2.2
4.2
ug/l
—
10
95
5
41
1.09
0.09
1.0
1.3
—
125.8
—
0
7
17
166
0.91
0.09
2.3
2.2
—
—
—
0
0
392
3540
0.99
0.09
1.2
1.3
9.6
10.0
u/l
0.29
337
2871
41
384
0.95
0.08
1.1
1.0
8.9
9.3
u/ml
—
10
54
140
1219
1.02
0.08
1.2
1.2
—
—
—
0
0
6
52
1.03
0.08
1.0
1.1
—
14.8
—
0
11
5
54
0.83
0.08
1.0
1.0
—
—
—
0
0
6
63
0.85
0.07
3.0
2.1
2.3
2.7
ug/l
—
6
58
6
65
0.82
0.07
1.3
1.3
—
—
—
0
0
6
66
0.81
0.07
1.3
1.2
—
—
—
0
0
8
70
1.02
0.07
1.9
1.9
—
—
—
0
0
7
73
0.85
0.07
2.0
1.8
—
—
—
0
0
7
74
0.84
0.07
1.0
1.3
—
21.8
—
0
8
9
92
0.87
0.06
1.2
1.5
—
—
—
0
0
1420
12713
0.99
0.06
2.5
2.5
—
—
—
0
0
291
2623
0.99
0.06
2.1
3.7
5.7
5.8
kpa
1.18
286
2532
15
144
0.93
0.05
1.1
1.1
—
—
—
0
0
48
414
1.03
0.05
1.0
1.1
388.8
412.7
nmol/l
0.41
43
396
92
837
0.98
0.05
2.0
2.0
0.3
1.9
ug/l
3.63
83
724
79
720
0.98
0.05
1.1
1.0
2.1
1.1
u/ml
0.30
18
198
32
274
1.04
0.04
1.4
1.5
64410.7
38538.7
e6/l
0.15
21
192
38
350
0.97
0.04
1.3
1.1
—
—
—
0
0
113
1022
0.99
0.04
1.7
2.6
24.4
24.4
mmol/l
0.14
100
953
53
484
0.98
0.04
2.0
2.0
40.9
48.1
%
—
8
78
18
169
0.95
0.03
1.8
1.6
12.9
3.4
%
—
7
41
290
2601
0.99
0.03
2.1
3.8
1.7
1.5
mmol/l
0.55
222
2085
22
188
1.04
0.03
1.3
1.1
1.0
1.6
u/ml
—
7
34
26
240
0.97
0.02
2.0
2.1
226.7
168.2
e6/l
0.42
12
132
682
6099
1.00
0.02
1.6
1.8
—
—
—
0
0
50
455
0.98
0.02
2.8
2.4
0.2
0.2
e9/l
0.44
42
382
1071
9524
1.00
0.02
2.2
2.3
8.4
9.7
e6/l
1.54
900
8200
158
1398
1.01
0.02
1.1
1.1
—
—
—
0
0
67
605
0.99
0.01
1.9
1.9
—
—
—
0
0
15
140
0.95
0.01
1.2
1.4
36.8
35.5
g/l
0.18
15
131
11
92
1.07
0.01
1.0
1.1
—
—
—
0
0
573
5096
1.00
0.01
1.4
1.4
—
—
—
0
0
19
164
1.03
0.00
2.6
2.1
258.7
70.3
ng/l
0.48
13
98
30
262
1.02
0.00
2.3
1.6
2263.1
2428.6
ml
0.20
12
28
181
1619
1.00
0.00
1.3
1.3
1.2
1.6
nmol/l
3.33
159
1344
21
186
1.01
0.00
1.3
1.2
—
—
—
0
0
62
548
1.01
0.00
1.2
1.3
0.2
0.8
u/ml
1.43
16
186
37
334
0.99
0.00
1.2
1.1
—
—
—
0
0
287
2559
1.00
0.00
1.1
1.1
2.6
4.3
u/ml
0.86
49
436
95
846
1.00
0.00
3.1
2.0
129.8
131.7
g/l
0.48
72
663
36
324
0.99
0.00
2.3
2.4
57.0
54.4
%
0.22
17
196
52
466
0.99
0.00
2.7
2.4
643.2
520.7
e6/l
1.05
43
383
127
1135
1.00
0.00
2.0
2.7
—
—
—
0
0
24
213
1.00
0.00
1.0
1.1
4.3
1.2
u/ml
0.32
14
156
113
1005
1.00
0.00
3.9
4.0
—
—
—
0
0
28
249
1.00
0.00
1.2
1.3
—
—
—
0
0
5
46
0.97
0.00
1.0
1.1
1.3
1.4
umol/24h
—
5
46
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
71
1.00
0.00
1.1
1.5
1.8
3.0
mmol/l
—
8
63
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
22.0
—
0
5
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
6
62
0.86
0.00
1.2
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
6.1
—
12.3
—
0
8
0
8
0.00
-0.00
0.0
1.0
—
1023.7
—
0
8

Mortality – FinRegistry

Association

Association between endpoint O15_DELIV_PERIN_LACER and mortality.

Females

Parameter HR [95% CI] p-value
O15_DELIV_PERIN_LACER 0.416 [0.33, 0.52] < 0.001
Birth year 0.993 [0.98, 1.0] 0.094

During the follow-up period (1.1.1998 — 31.12.2019), 110 out of 42652 females with O15_DELIV_PERIN_LACER died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_DELIV_PERIN_LACER.

N-year risk Females Males
1 0.022% No data
5 0.178% No data
10 0.506% No data
15 1.004% No data
20 1.809% No data

Relationships between endpoints

Index endpoint: O15_DELIV_PERIN_LACER – Perineal laceration during delivery

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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