Risteys · O15_DELIV_PERIN

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule only females	293373
2. Check conditions None	293373
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — O70 Hospital discharge: ICD-9 — 664 Hospital discharge: ICD-8 — 6603 Cause of death: ICD-10 — O70 Cause of death: ICD-9 — 664 Cause of death: ICD-8 — 6603 2 out of 7 registries used, show all original rules.	7857
4. Check minimum number of events None	7857
5. Include endpoints None	7857
6. Filter based on genotype QC (FinnGen only)	7857

	All	Female	Male
Number of individuals
Whole population	57715	57715	-
Only index persons	57188	57188	-
Unadjusted period prevalence (%)
Whole population	1.65	1.65	-
Only index persons	2.10	2.10	-
Median age at first event (years)
Whole population	-	29.53	-
Only index persons	-	29.52	-

	All	Female	Male
Number of individuals	7857	7857	-
Unadjusted period prevalence (%)	2.68	2.68	-
Median age at first event (years)	30.14	30.14	-

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
6782: Matched controls
61705

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

Z34.0

ICD-10 Finland

Supervision of normal first pregnancy

4.1

323.0

2984

10013

Z36.3

ICD-10 Finland

Antenatal screening for malformations using ultrasound and other physical methods

4.9

323.0

4589

18473

MBC10

NOMESCO Finland

Repair of obstetric laceration of vagina

14.5

323.0

915

658

O75.6

ICD-10 Finland

Delayed delivery after spontaneous or unspecified rupture of membranes

+∞

323.0

323

MBC33

NOMESCO Finland

Repair of complete rupture of perineum

590.4

323.0

701

O70.0

ICD-10 Finland

First degree perineal laceration during delivery

5740.7

323.0

1086

MA2AE

NOMESCO Finland

Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus

3.9

323.0

3202

11486

O68.0

ICD-10 Finland

Labour and delivery complicated by fetal heart rate anomaly

9082.7

323.0

881

MA2JE

NOMESCO Finland

Ultrasound screening of fetal nuchal translucency

4.0

323.0

2092

6214

Z39.2

ICD-10 Finland

Routine postpartum follow-up

5.0

323.0

3341

9979

O72.1

ICD-10 Finland

Other immediate postpartum haemorrhage

1066.3

323.0

638

O63.1

ICD-10 Finland

Prolonged second stage (of labour)

+∞

323.0

646

MBA30

NOMESCO Finland

Manual removal of placenta from delivered uterus

78.2

323.0

419

W78

ICPC

Pregnancy

4.1

323.0

3556

13177

O81.4

ICD-10 Finland

Vacuum extractor delivery

59.5

323.0

1613

322

MAE00

NOMESCO Finland

Outlet vacuum delivery

54.9

323.0

1384

287

SPAT1380

SPAT

Postpartum check-up

4.0

323.0

2490

7746

SPAT1379

SPAT

Health check-up of pregnant person

4.2

323.0

2955

9503

O72.0

ICD-10 Finland

Third-stage haemorrhage

+∞

323.0

592

66030

ICD-8 Finland

Occipital presentation

+∞

323.0

387

SPAT1197

SPAT

Extensive health check-up of expecting family

4.6

323.0

3363

10800

O70.2

ICD-10 Finland

Third degree perineal laceration during delivery

+∞

323.0

757

O70.1

ICD-10 Finland

Second degree perineal laceration during delivery

8679.0

323.0

3752

MA2HE

NOMESCO Finland

Detailed morfological ultrasound examination of fetus

3.8

323.0

3239

11894

MBC30

NOMESCO Finland

Repair of partial rupture of perineum

68.1

323.0

1710

304

MAX99

NOMESCO Finland

Assistance to normal delivery

3.5

323.0

2412

8369

Z34.8

ICD-10 Finland

Supervision of other normal pregnancy

3.3

323.0

2793

10908

O80.8

ICD-10 Finland

Other single spontaneous delivery

5.1

323.0

1287

2684

WX307

NOMESCO Finland

Obstetric epidural analgesia

3.4

306.3

1835

6068

O64.0

ICD-10 Finland

Obstructed labour due to incomplete rotation of fetal head

+∞

276.3

273

O70.21

ICD-10 Finland

III degree perineal tear involving less than one half of external anal sphincter thickness torn during childbirth

+∞

258.0

255

O80.0

ICD-10 Finland

Spontaneous vertex delivery

2.4

255.0

4078

23714

Z37.0

ICD-10 Finland

Single live birth

2.9

233.8

1794

6852

O75.0

ICD-10 Finland

Maternal distress during labour and delivery

+∞

229.5

227

O72.2

ICD-10 Finland

Delayed and secondary postpartum haemorrhage

131.7

227.0

251

TMA00

NOMESCO Finland

Episiotomy

5.0

223.8

800

1616

ZXD05

NOMESCO Finland

Urgent procedure

2.5

221.8

2429

11347

O60

ICD-10 Finland

Preterm labour and delivery

530.0

220.6

226

SPAT1317

SPAT

Planned health check-up monitoring, health check-up performed based on individual need

2.8

211.5

1739

6865

MA3AE

NOMESCO Finland

Combined first trimester screening

3.6

208.3

1069

3026

6641B

ICD-9 Finland

Trauma to perineum and vulva during delivery, Second-degree perineal laceration

+∞

206.1

204

MA5AE

NOMESCO Finland

Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation

3.5

193.1

1042

3057

O99.80

ICD-10 Finland

The fear of childbirth

3.7

190.0

941

2573

O70.22

ICD-10 Finland

III degree perineal tear involving one half or more of external anal sphincter thickness torn during childbirth

+∞

188.8

187

O34.2

ICD-10 Finland

Maternal care due to uterine scar from previous surgery

5.0

187.2

655

1282

SPAT1399

SPAT

Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.

3.6

187.0

961

2706

O24.4

ICD-10 Finland

Diabetes mellitus arising in pregnancy

2.8

184.7

1390

5136

MCA10

NOMESCO Finland

Lower uterine segment caesarean section

3.3

176.5

1040

3243

O71.4

ICD-10 Finland

Obstetric high vaginal laceration

+∞

174.6

173

MA1AE

NOMESCO Finland

Ultrasound examination of early pregnancy (before 12. postmenstrual week)

2.4

173.6

1837

8207

SPAT1195

SPAT

Antenatal classes

4.1

170.9

732

1752

Z34

ICD-10 Finland

Supervision of normal pregnancy

3.3

170.6

995

3075

MA2DE

NOMESCO Finland

Detailed ultrasound examination of fetus including color doppler method

2.6

169.6

1461

5822

SPAT1196

SPAT

Monitoring of normal pregnancy

2.7

167.0

1384

5386

Z39.1

ICD-10 Finland

Care and examination of lactating mother

5.7

163.4

510

870

SPAT1200

SPAT

Guidance for breast-feeding and breast care

4.2

159.4

671

1576

Z3232

NOMESCO Finland

Midwife

2.5

159.3

1569

6701

Z32.1

ICD-10 Finland

Pregnancy confirmed

2.4

159.0

1713

7666

Z36.8

ICD-10 Finland

Other antenatal screening

5.4

158.5

518

933

Z34.9

ICD-10 Finland

Supervision of normal pregnancy, unspecified

2.3

158.3

1774

8096

Z35.2

ICD-10 Finland

Supervision of pregnancy with other poor reproductive or obstetric history

6.8

156.1

424

603

O73.0

ICD-10 Finland

Retained placenta without haemorrhage

+∞

155.3

154

O47.0

ICD-10 Finland

False labour before 37 completed weeks of gestation

2.5

152.9

1413

5815

SPAT1373

SPAT

Combined screening in early pregnancy

5.4

151.4

494

887

O63.0

ICD-10 Finland

Prolonged first stage (of labour)

+∞

144.2

143

W85

ICPC

Gestational diabetes

3.3

140.0

790

2360

WX306

NOMESCO Finland

Lumbar epidural anesthesy

3.0

134.8

902

3032

Z35.8

ICD-10 Finland

Supervision of other high-risk pregnancies

2.4

132.4

1290

5411

W92

ICPC

Compl labour/ delivery livebirth

6.0

127.6

380

608

SPAT1246

SPAT

Screening of depression or other psychiatric problem

3.0

119.5

788

2612

MAC96

NOMESCO Finland

Other induction or advancement of labour

4.1

118.7

501

1169

O64.1

ICD-10 Finland

Obstructed labour due to breech presentation

1101.0

117.9

119

WX600

NOMESCO Finland

Single shot through catheter

7.3

112.8

289

376

8833

FHL

Correction of II ^ 0 or III ^ 0 perineumrupth or vaginal rupture

81.0

112.7

131

MBA04

NOMESCO Finland

Curettage of uterus after delivery

55.7

112.5

138

O68.1

ICD-10 Finland

Labour and delivery complicated by meconium in amniotic fluid

+∞

111.8

111

MBC20

NOMESCO Finland

Repair of obstetric laceration of vulva

19.1

109.4

174

W90

ICPC

Uncompl labour/delivery livebirth

2.5

106.8

932

3646

6640B

ICD-9 Finland

Trauma to perineum and vulva during delivery, First-degree perineal laceration

+∞

106.8

106

O70.3

ICD-10 Finland

Fourth degree perineal laceration during delivery

950.5

101.8

103

O82.10

ICD-10 Finland

Delivery by emergency caesarean section

4.2

100.3

411

930

O68.8

ICD-10 Finland

Labour and delivery complicated by other evidence of fetal stress

+∞

99.7

O73.1

ICD-10 Finland

Retained portions of placenta and membranes, without haemorrhage

+∞

99.7

MAC40

NOMESCO Finland

Pharmacological induction or advancement of labor

4.7

94.9

344

688

MAC10

NOMESCO Finland

Antepartum dilatation of cervical canal

3.9

92.8

420

1039

SPAT1189

SPAT

Other ultrasound examination during pregnancy

2.9

92.1

637

2161

W84

ICPC

Pregnancy high risk

2.9

90.6

619

2080

MAC01

NOMESCO Finland

Rupture of aminiotic membrane for induction of labor

4.3

89.9

360

796

W29

ICPC

Pregnancy symptom/complaint other

3.2

88.7

524

1596

O62.1

ICD-10 Finland

Secondary uterine inertia

+∞

88.6

O70.9

ICD-10 Finland

Perineal laceration during delivery, unspecified

175.3

88.0

Z36.4

ICD-10 Finland

Antenatal screening for fetal growth retardation using ultrasound and other physical methods

5.0

87.5

299

561

O48

ICD-10 Finland

Prolonged pregnancy

3.1

85.8

525

1638

TMW99

NOMESCO Finland

Other minor surgical procedure in obstetrics

7.0

84.6

220

292

WYA40

NOMESCO Finland

Assessment of oral health and treatment needs for family expecting first child

3.7

83.0

387

981

O36.6

ICD-10 Finland

Maternal care for excessive fetal growth

3.1

82.9

504

1565

OAA12

SPAT

4.1

82.3

345

795

SPAT1375

SPAT

Structural ultrasound screening, weeks 18+0-21+6

5.0

81.4

281

533

WX321

NOMESCO Finland

Acute spinal anesthesia for delivery

2.5

81.3

711

2757

XMA22

NOMESCO Finland

General examination of pregnant woman

2.3

80.9

849

3617

MA2XE

NOMESCO Finland

Other obstetric ultrasound examination

2.2

80.6

953

4291

WW500

NOMESCO Finland

Blood transfusion

5.4

79.7

253

436

OAA11

SPAT

2.8

79.3

547

1846

6642B

ICD-9 Finland

Trauma to perineum and vulva during delivery, Third-degree perineal laceration

+∞

78.5

O61.0

ICD-10 Finland

Failed medical induction of labour

+∞

77.5

O61.8

ICD-10 Finland

Other failed induction of labour

+∞

76.5

XJH00

NOMESCO Finland

Transanal ultrasonography

8.4

75.0

173

191

O47.9

ICD-10 Finland

False labour, unspecified

4.0

73.2

317

752

6645B

ICD-9 Finland

Trauma to perineum and vulva during delivery, Vulval and perineal haematoma

+∞

72.4

Z35.0

ICD-10 Finland

Supervision of pregnancy with history of infertility

3.1

72.4

441

1369

O68.2

ICD-10 Finland

Labour and delivery complicated by fetal heart rate anomaly with meconium in amniotic fluid

+∞

68.4

JHC00

NOMESCO Finland

Suture of anal sphincter

220.6

67.8

O34.7

ICD-10 Finland

Maternal care for abnormality of vulva and perineum

61.3

66.5

WX320

NOMESCO Finland

Spinalanesthesy

1.9

64.7

1044

5297

WX322

NOMESCO Finland

Combined spinal-epidural analgesia in obstetrics

3.4

61.8

320

881

WX230

NOMESCO Finland

Plexus blockade of nervus pudendus

4.1

61.6

256

585

O66.0

ICD-10 Finland

Obstructed labour due to shoulder dystocia

+∞

61.4

O42.0

ICD-10 Finland

Premature rupture of membranes, onset of labour within 24 hours

3.9

60.3

267

646

Z87.5

ICD-10 Finland

Personal history of complications of pregnancy, childbirth and the puerperium

5.8

60.2

180

289

MAC00

NOMESCO Finland

Rupture of amniotic membrane

11.0

57.5

114

SPAT1357

SPAT

Monitoring of problem during pregnancy

2.6

57.5

451

1637

WX602

NOMESCO Finland

Repeated or continuing anesthesia shots throug a catheter

1.9

56.8

897

4497

O64.8

ICD-10 Finland

Obstructed labour due to other malposition and malpresentation

530.7

56.6

O42.9

ICD-10 Finland

Premature rupture of membranes, unspecified

2.6

55.8

447

1640

O75.7

ICD-10 Finland

Vaginal delivery following previous caesarean section

+∞

52.3

MAE03

NOMESCO Finland

Mid-cavity or high vacuum delivery

41.0

52.1

Z36.0

ICD-10 Finland

Antenatal screening for chromosomal anomalies

2.0

51.3

695

3274

O26.82

ICD-10 Finland

Exhaustion and fatigue pregnancy-related

3.0

50.5

316

996

N05AH04

ATC

quetiapine; oral

0.5

49.6

521

8481

WX234

NOMESCO Finland

Paracervical blockade

2.4

48.3

445

1759

O13

ICD-10 Finland

Gestational [pregnancy-induced] hypertension

2.2

48.2

544

2369

O71.3

ICD-10 Finland

Obstetric laceration of cervix

438.0

46.6

R3110

NOMESCO Finland

Psychosocial training

3.5

46.0

229

611

O68.3

ICD-10 Finland

Labour and delivery complicated by biochemical evidence of fetal stress

+∞

45.2

O36.8

ICD-10 Finland

Maternal care for other specified fetal problems

3.2

44.3

251

739

O02.1

ICD-10 Finland

Missed abortion

1.9

43.8

667

3281

MBC00

NOMESCO Finland

Repair of obstetric laceration of cervix uteri

74.9

42.1

O32.1

ICD-10 Finland

Maternal care for breech presentation

2.2

40.9

468

2048

O62.0

ICD-10 Finland

Primary inadequate contractions

+∞

40.2

O82.11

ICD-10 Finland

Childbirth with an emergency caesarean section in an emergency

11.2

40.1

O20.9

ICD-10 Finland

Haemorrhage in early pregnancy, unspecified

2.3

40.0

379

1517

MAW96

NOMESCO Finland

Other operation in pregnancy or at delivery

7.6

39.6

116

O69.1

ICD-10 Finland

Labour and delivery complicated by cord around neck, with compression

+∞

39.2

Z12.4

ICD-10 Finland

Special screening examination for neoplasm of cervix

2.6

38.4

289

1022

6611B

ICD-9 Finland

Abnormality of forces of labour, Secondary uterine inertia

+∞

38.2

R15

ICD-10 Finland

Faecal incontinence

4.5

37.9

139

283

112

Kela drug reimbursment

Severe psychotic and other severe mental disorders

0.3

37.6

114

2909

XJH10

NOMESCO Finland

Anorectal manometry

13.0

37.5

6622B

ICD-9 Finland

Long labour, Prolonged second stage

+∞

37.2

OAA10

SPAT

2.6

36.7

283

1013

LA2AE

NOMESCO Finland

Ultrasound examination of ovarian cyst

2.3

36.0

345

1387

O86.0

ICD-10 Finland

Infection of obstetric surgical wound

4.9

35.8

121

226

MAC02

NOMESCO Finland

Rupture of aminiotic membrane for advancement of labor

5.1

35.1

115

208

O36.9

ICD-10 Finland

Maternal care for fetal problem, unspecified

3.7

34.9

159

396

O67.9

ICD-10 Finland

Intrapartum haemorrhage, unspecified

+∞

34.2

O24.9

ICD-10 Finland

Diabetes mellitus in pregnancy, unspecified

2.8

33.9

233

779

ZXH09

SPAT

3.0

33.7

206

640

O26.7

ICD-10 Finland

Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium

3.4

33.7

173

475

MAA40

NOMESCO Finland

Puncture of fetus

6.3

33.5

134

Z30.1

ICD-10 Finland

Insertion of (intrauterine) contraceptive device

1.5

33.1

1648

11146

Z39

ICD-10 Finland

Postpartum care and examination

3.2

33.0

183

532

Z32

ICD-10 Finland

Pregnancy examination and test

3.5

32.4

160

426

O86.1

ICD-10 Finland

Other infection of genital tract following delivery

4.3

32.0

122

259

O71.7

ICD-10 Finland

Obstetric haematoma of pelvis

299.3

31.7

O26.88

ICD-10 Finland

Other specified pregnancy-related conditions

2.9

31.5

206

667

6522B

ICD-9 Finland

Malposition and malpresentation of foetus, Breech presentation without mention of version[PRAESENTATIO CLUNIUM,SYNNYTYKSEN AIKANA]

+∞

31.2

O66.5

ICD-10 Finland

Failed application of vacuum extractor and forceps, unspecified

+∞

31.2

8836

FHL

Evacuation of a vulva or paravaginal hematoma

65.9

30.5

MBA40

NOMESCO Finland

Pharmacological evacuation of uterus after abortion

2.6

30.5

242

881

MBA03

NOMESCO Finland

Curettage of uterus after delivery or abortion

2.5

30.5

249

922

N06AX16

ATC

venlafaxine; oral

0.6

30.2

485

7134

6660A

ICD-9 Finland

Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM STADII III]

+∞

30.2

O35.8

ICD-10 Finland

Maternal care for other (suspected) fetal abnormality and damage

2.5

29.7

247

925

SPAT1315

SPAT

Periodic health check-up of children and adolescents

1.9

29.6

490

2472

Z32.0

ICD-10 Finland

Pregnancy, not (yet) confirmed

2.1

29.6

349

1544

O41.8

ICD-10 Finland

Other specified disorders of amniotic fluid and membranes

7.1

29.4

TQW30

NOMESCO Finland

Acupuncture

4.5

29.2

108

223

LC2BE

NOMESCO Finland

Transvaginal ultrasound examination of uterus, parametria and lower abdomen

1.4

29.1

2692

20211

ZXE00

NOMESCO Finland

One hour or less

1.4

29.1

2291

16759

O99.2

ICD-10 Finland

Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium

2.6

28.6

218

778

SPAT1249

SPAT

Treatment-related counselling outside office

1.3

28.6

2663

19998

N05AX12

ATC

aripiprazole; systemic

0.3

28.5

2172

N05AH03

ATC

olanzapine; systemic

0.4

28.3

107

2494

O62.3

ICD-10 Finland

Precipitate labour

+∞

28.1

N06AX11

ATC

mirtazapine; oral

0.7

27.8

1078

13271

MAC99

NOMESCO Finland

Other augmentation of labor

73.2

27.6

O41.0

ICD-10 Finland

Oligohydramnios

2.5

27.5

226

840

MBC40

NOMESCO Finland

Revision of paravaginal or vulvar haematoma after delivery or abortion

26.7

27.1

O82.0

ICD-10 Finland

Delivery by elective caesarean section

1.9

27.1

404

1962

O91.2

ICD-10 Finland

Nonpurulent mastitis associated with childbirth

2.8

27.1

180

590

SPAT1324

SPAT

Screening procedure

1.4

26.6

1778

12605

8832

FHL

Manual placenta removal and associated scraping

132.5

26.6

MAE20

NOMESCO Finland

Failed vacuum delivery

91.4

26.5

O75.2

ICD-10 Finland

Pyrexia during labour, not elsewhere classified

+∞

26.1

6441A

ICD-9 Finland

Early or threatened labour, Other threatened labour

+∞

26.1

F29

ICD-10 Finland

Unspecified nonorganic psychosis

0.3

26.0

1687

O21.9

ICD-10 Finland

Vomiting of pregnancy, unspecified

2.6

25.8

199

714

O62.2

ICD-10 Finland

Other uterine inertia

68.6

25.7

8801

FHL

Suction cup delivery

4.9

25.5

158

N05AX08

ATC

risperidone; systemic

0.4

25.4

2207

G03GA05

ATC

follitropin alfa; parenteral

1.9

25.1

376

1831

OAB47

SPAT

2.3

25.0

247

1008

SPAT1187

SPAT

General ultrasound examination in early pregnancy

3.0

24.7

152

475

X23

ICPC

Fear sexually transm dis female

0.6

24.6

359

5423

SPAT1190

SPAT

Insertion or removal of intrauterine contraceptive device

1.5

24.1

811

5000

SPAT1128

SPAT

Instruction of pelvic floor / sphincter exercises

3.3

24.1

126

353

JHC10

NOMESCO Finland

Reconstruction of anal sphincter without graft

32.5

24.0

O99.89

ICD-10 Finland

Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium

2.2

24.0

241

994

MBC96

NOMESCO Finland

Other repair of obstetric laceration

118.7

23.6

O47.1

ICD-10 Finland

False labour at or after 37 completed weeks of gestation

1.8

23.6

420

2171

LFE20

NOMESCO Finland

Suture of perineum

31.5

23.1

W18

ICPC

Post-partum symptom/complaint other

4.1

23.0

211

N05CF01

ATC

zopiclone; oral

0.7

22.9

755

9606

SPAT1381

SPAT

Extensive health check-up at 4 months of age

3.7

22.8

104

262

O41.1

ICD-10 Finland

Infection of amniotic sac and membranes

5.6

22.7

112

Z35.9

ICD-10 Finland

Supervision of high-risk pregnancy, unspecified

1.9

22.7

343

1673

OAA41

SPAT

2.9

22.3

139

439

6654B

ICD-9 Finland

Other obstetrical trauma, High vaginal laceration

+∞

22.1

63497

ICD-8 Finland

Other complications of pregnancy, Partus prematurus imminens, alibi non classificabilis

+∞

22.1

SPAT1236

SPAT

Informing family of child’s disability

3.3

21.8

112

310

O71.8

ICD-10 Finland

Other specified obstetric trauma

76.1

21.7

Z39.0

ICD-10 Finland

Care and examination immediately after delivery

2.8

21.5

147

492

O42.1

ICD-10 Finland

Premature rupture of membranes, onset of labour after 24 hours

3.0

21.3

129

401

Z35

ICD-10 Finland

Supervision of high-risk pregnancy

2.9

21.3

135

433

OAA70

SPAT

3.1

21.2

120

355

6648B

ICD-9 Finland

Trauma to perineum and vulva during delivery, Other specified trauma to perineum and vulva

+∞

21.1

6440B

ICD-9 Finland

Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS]

+∞

21.1

N05BA04

ATC

oxazepam; oral

0.7

21.0

872

10682

Z71.9

ICD-10 Finland

Counselling, unspecified

1.8

20.8

354

1800

N97.9

ICD-10 Finland

Female infertility, unspecified

1.5

20.6

665

4056

H01CC01

ATC

ganirelix; parenteral

1.9

20.2

311

1530

SPAT1382

SPAT

Extensive health check-up at 18 months of age

3.5

20.1

252

M01AH05

ATC

etoricoxib; oral

0.8

19.9

2414

25552

N06AX12

ATC

bupropion; oral

0.6

19.8

227

3653

SPAT1308

SPAT

Sexual health counselling

1.3

19.5

1822

13480

LX1AE

NOMESCO Finland

Gynecological ultrasound examination as part of clinical examination

1.4

19.3

1073

7310

O99.0

ICD-10 Finland

Anaemia complicating pregnancy, childbirth and the puerperium

2.8

19.2

123

398

O65.5

ICD-10 Finland

Obstructed labour due to abnormality of maternal pelvic organs

+∞

19.1

O68.9

ICD-10 Finland

Labour and delivery complicated by fetal stress, unspecified

+∞

19.1

N05BA01

ATC

diazepam; systemic, rectal

0.6

18.9

232

3669

SPAT1391

SPAT

Counselling and guidance related to family situation

2.4

18.7

161

615

F20.9

ICD-10 Finland

Schizophrenia, unspecified

0.1

18.7

563

O47

ICD-10 Finland

False labour

2.8

18.6

123

406

O03.9

ICD-10 Finland

Spontaneous abortion, Complete or unspecified, without complication

1.6

18.4

463

2652

Z10.8

ICD-10 Finland

Routine general health check-up of other defined subpopulations

1.8

18.3

316

1617

N05CF02

ATC

zolpidem; oral

0.7

18.2

529

6917

O14.9

ICD-10 Finland

Pre-eclampsia, unspecified

2.5

18.1

145

534

G03GA01

ATC

chorionic gonadotrophin; parenteral

1.7

18.1

427

2405

N03AX09

ATC

lamotrigine; oral

0.5

17.7

154

2678

W05

ICPC

Pregnancy vomiting/nausea

2.6

17.5

131

465

N02AX02

ATC

tramadol; systemic, rectal

0.7

17.5

1115

12855

SPAT1192

SPAT

Gynaecological examination

1.3

17.5

1310

9358

P72

ICPC

Schizophrenia

0.1

17.3

507

6660C

ICD-9 Finland

Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM CUM RETENT PLAC PARTIALI]

+∞

17.1

SPAT1312

SPAT

General health counselling

1.3

17.0

2074

15845

ZXD00

NOMESCO Finland

Emergency procedure

2.4

17.0

145

555

O99.3

ICD-10 Finland

Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium

2.0

16.9

209

945

N61

ICD-10 Finland

Inflammatory disorders of breast

1.8

16.8

273

1370

OAB30

SPAT

3.3

16.6

237

MBA96

NOMESCO Finland

Other removal of retained products of conception after delivery or abortion

2.1

16.5

192

848

SPAT1393

SPAT

Guidance to support interaction between parent and child

3.2

16.3

250

N06AB10

ATC

escitalopram; oral

0.8

16.2

1058

12173

N05AH02

ATC

clozapine; systemic

0.2

16.2

689

T36

ICD-10 Finland

Poisoning by systemic antibiotics

0.5

16.1

103

1974

6660B

ICD-9 Finland

Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM CUM RETENT PLAC TOTALI]

+∞

16.1

6528B

ICD-9 Finland

Malposition and malpresentation of foetus, Other specified malposition or malpresentation[MUUT VIRHEASENNOT JA -TARJONNAT, SYNNYTYKSEN AIKANA]

+∞

16.1

SPAT1389

SPAT

Visit based on need for special support

1.8

16.0

266

1345

N06AB03

ATC

fluoxetine; oral

0.6

15.9

365

5000

O02.0

ICD-10 Finland

Blighted ovum and nonhydatidiform mole

1.8

15.9

296

1553

O90.1

ICD-10 Finland

Disruption of perineal obstetric wound

5.8

15.8

LAA10

NOMESCO Finland

Percutaneous or transvaginal puncture and recovery of oocyte

1.8

15.4

285

1496

O20.0

ICD-10 Finland

Threatened abortion

1.9

15.1

234

1154

O26.6

ICD-10 Finland

Liver disorders in pregnancy, childbirth and the puerperium

2.2

15.1

156

654

O66.2

ICD-10 Finland

Obstructed labour due to unusually large fetus

+∞

15.1

O66.8

ICD-10 Finland

Other specified obstructed labour

+∞

15.1

W27

ICPC

Fear of complications of pregnancy

2.4

15.0

134

524

O32.2

ICD-10 Finland

Maternal care for transverse and oblique lie

3.4

15.0

197

O46.9

ICD-10 Finland

Antepartum haemorrhage, unspecified

2.1

14.9

169

741

ZXA00

NOMESCO Finland

Right side

0.7

14.8

468

6036

WZB00

SPAT

0.6

14.8

199

3077

N06AB06

ATC

sertraline; oral

0.7

14.7

420

5515

Z76.0

ICD-10 Finland

Issue of repeat prescription

0.7

14.6

511

6471

TLW00

NOMESCO Finland

Insemination

1.8

14.4

232

1165

F20.00

ICD-10 Finland

Paranoid schizophrenia continuous

0.1

14.2

502

E10.7

ICD-10 Finland

Type 1 diabetes mellitus, With multiple complications

0.2

14.1

577

6670A

ICD-9 Finland

Retained placenta or membranes, without haemorrhage, Retained placenta without haemorrhage

+∞

14.1

O67.8

ICD-10 Finland

Other intrapartum haemorrhage

+∞

14.1

6661A

ICD-9 Finland

Postpartum haemorrhage, Other immediate postpartum haemorrhage[HAEMORRHAGIA POST PARTUM ATONICA UTERI]

+∞

14.1

65300

ICD-8 Finland

Occipital presentation

+∞

14.1

N81.6

ICD-10 Finland

Rectocele

1.9

14.0

221

1098

Z09.0

ICD-10 Finland

Follow-up examination after surgery for other conditions

1.6

13.9

393

2319

F33.2

ICD-10 Finland

Recurrent depressive disorder, current episode severe without psychotic symptoms

0.5

13.8

148

2425

F32.2

ICD-10 Finland

Severe depressive episode without psychotic symptoms

0.6

13.7

236

3440

F32.10

ICD-10 Finland

Moderate depressive episode without somatic syndrome

0.7

13.7

376

4974

O30.0

ICD-10 Finland

Twin pregnancy

2.3

13.6

127

510

O35.9

ICD-10 Finland

Maternal care for (suspected) fetal abnormality and damage, unspecified

2.4

13.5

112

423

F60.30

ICD-10 Finland

Emotionally unstable personality disorder, impulsive

0.4

13.3

1191

F10.1

ICD-10 Finland

Mental and behavioural disorders due to use of alcohol, Harmful use

0.5

13.3

1512

O35.1

ICD-10 Finland

Maternal care for (suspected) chromosomal abnormality in fetus

2.0

13.2

170

786

F32.9

ICD-10 Finland

Depressive episode, unspecified

0.7

13.2

581

7096

TLW12

NOMESCO Finland

Insertion of frozen embryo

1.9

13.1

188

904

SPAT1188

SPAT

Monitoring of foetal growth

3.2

13.1

194

X69

ICD-10 Finland

Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances

0.5

13.1

1556

O75.3

ICD-10 Finland

Other infection during labour

+∞

13.1

O64.9

ICD-10 Finland

Obstructed labour due to malposition and malpresentation, unspecified

+∞

13.1

6644B

ICD-9 Finland

Trauma to perineum and vulva during delivery, Unspecified perineal laceration

+∞

13.1

MAA00

NOMESCO Finland

Amniocentesis

1.9

13.0

181

860

L02BG04

ATC

letrozole; oral

1.6

13.0

368

2172

I10

ICD-10 Finland

Essential (primary) hypertension

0.7

12.9

704

8335

N03AX12

ATC

gabapentin; oral

0.7

12.9

322

4338

F20.30

ICD-10 Finland

Undifferentiated schizophrenia continuous

0.1

12.9

425

N05CD07

ATC

temazepam; oral

0.5

12.9

1496

N03AX16

ATC

pregabalin; oral

0.7

12.7

565

6895

XJG12

NOMESCO Finland

Transrectal endoscopic ultrasonography

11.0

12.7

Z20.2

ICD-10 Finland

Contact with and exposure to infections with a predominantly sexual mode of transmission

0.5

12.7

1677

F41.9

ICD-10 Finland

Anxiety disorder, unspecified

0.7

12.6

507

6288

Z25.8

ICD-10 Finland

Need for immunization against other specified single viral diseases

1.4

12.6

692

4686

E10.1

ICD-10 Finland

Type 1 diabetes mellitus, With ketoacidosis

0.1

12.5

435

O90.8

ICD-10 Finland

Other complications of the puerperium, not elsewhere classified

6.5

12.5

MBA05

NOMESCO Finland

Curettage of uterus after abortion

2.2

12.3

120

494

N05AN01

ATC

lithium; oral

0.3

12.3

931

ZXE20

NOMESCO Finland

More than three and less than five hours

0.6

12.3

202

2977

N05AA02

ATC

levomepromazine; systemic

0.4

12.3

960

N05BA06

ATC

lorazepam; systemic, sublingual

0.4

12.3

1017

O65.4

ICD-10 Finland

Obstructed labour due to fetopelvic disproportion, unspecified

45.6

12.3

N97.0

ICD-10 Finland

Female infertility associated with anovulation

1.7

12.3

242

1295

O84.8

ICD-10 Finland

Other multiple delivery

6.4

12.3

O03.1

ICD-10 Finland

Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage

2.0

12.3

156

717

O85

ICD-10 Finland

Puerperal sepsis

2.5

12.3

331

8831

FHL

Uterine exploration and / or scraping or suction emptying (ad 24 hours)

17.3

12.2

A10AA01

ATC

0.3

12.2

809

F41.2

ICD-10 Finland

Mixed anxiety and depressive disorder

0.7

12.1

491

6081

SPAT1193

SPAT

Pap smear

1.3

12.1

1096

8006

O61.1

ICD-10 Finland

Failed instrumental induction of labour

+∞

12.1

6620B

ICD-9 Finland

Long labour, Prolonged first stage

+∞

12.1

W94

ICPC

Puerperal mastitis

2.4

12.0

370

M03BX02

ATC

tizanidine; oral

0.8

12.0

3128

31271

A10AB01

ATC

insulin (human); parenteral (insulins and analog. for injection, fast-acting)

0.4

12.0

1103

O99.1

ICD-10 Finland

Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium

2.6

12.0

292

O64.3

ICD-10 Finland

Obstructed labour due to brow presentation

118.5

12.0

MAF00

NOMESCO Finland

Outlet forceps cephalic delivery

118.5

12.0

N81.1

ICD-10 Finland

Cystocele

1.8

11.8

191

962

WZA10

SPAT

0.2

11.7

492

TLW10

NOMESCO Finland

Transfer of fresh embryo

1.8

11.7

190

960

A10AA02

ATC

0.3

11.7

805

Z31.1

ICD-10 Finland

Artificial insemination

3.0

11.6

211

F32

ICD-10 Finland

Depressive episode

0.6

11.6

199

2900

L17

ICPC

Foot/toe symptom/complaint

0.8

11.6

720

8379

6500B

ICD-9 Finland

Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]

0.7

11.6

496

6092

O23.5

ICD-10 Finland

Infections of the genital tract in pregnancy

2.3

11.5

108

435

O36.5

ICD-10 Finland

Maternal care for poor fetal growth

1.7

11.5

259

1443

103

Kela drug reimbursment

Diabetes, insulin-treated

0.7

11.5

299

4003

O86.8

ICD-10 Finland

Other specified puerperal infections

3.9

11.5

107

F60.31

ICD-10 Finland

Emotionally unstable personality disorder, borderline condition

0.4

11.4

943

M03BC01

ATC

orphenadrine (citrate); systemic

0.8

11.4

1003

11183

G47.3

ICD-10 Finland

Sleep apnoea

0.7

11.4

308

4091

F40.1

ICD-10 Finland

Social phobias

0.4

11.4

1212

WX110

SPAT

0.5

11.2

101

1737

G03GA06

ATC

follitropin beta; parenteral

1.7

11.1

224

1208

N03AG01

ATC

valproic acid; systemic, rectal

0.6

11.1

138

2170

8811

FHL

Cesarean section

2.2

11.1

113

476

SPAT1374

SPAT

Serum screening during second trimester

14.9

11.0

ZXH06

SPAT

2.1

11.0

117

500

N02AJ06

ATC

codeine and paracetamol; systemic

0.8

11.0

1483

15798

MBA00

NOMESCO Finland

Vacuum aspiration from uterus after delivery or abortion

1.9

11.0

167

825

H3603, E103

ICD-10 Finland

0.1

11.0

330

O80.9

ICD-10 Finland

Single spontaneous delivery, unspecified

2.2

11.0

107

441

Z2445

NOMESCO Finland

Psychologist

0.5

10.9

107

1795

W03

ICPC

Antepartum bleeding

2.3

10.8

379

215

Kela drug reimbursment

Diabetes, non-insulin-treated

0.7

10.8

298

3947

O20.8

ICD-10 Finland

Other haemorrhage in early pregnancy

2.9

10.8

201

E10.3

ICD-10 Finland

Type 1 diabetes mellitus, With ophthalmic complications

0.4

10.8

1056

O92.7

ICD-10 Finland

Other and unspecified disorders of lactation

3.6

10.8

118

WW200

SPAT

1.4

10.8

568

3815

Z3229

NOMESCO Finland

Other healthcare associate professional

0.5

10.7

113

1860

F32.1

ICD-10 Finland

Moderate depressive episode

0.6

10.7

234

3240

K05.31

ICD-10 Finland

Periodontitis pronounced

0.5

10.7

1503

O24

ICD-10 Finland

Diabetes mellitus in pregnancy

3.4

10.7

138

C07AA05

ATC

propranolol; systemic

0.8

10.6

834

9431

O99.4

ICD-10 Finland

Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium

2.9

10.6

212

GD1AA

NOMESCO Finland

Thorax X-ray examination

0.8

10.6

966

10739

2500B

ICD-9 Finland

Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]

0.3

10.6

723

M03BC51

ATC

orphenadrine, combinations; systemic

0.8

10.5

1137

12401

W12

ICPC

Contraception intrauterine

1.3

10.5

1211

9106

W78

ICD-10 Finland

Inhalation of gastric contents

4.6

10.4

O14.0

ICD-10 Finland

Mild to moderate pre-eclampsia

1.9

10.4

148

713

WX740

NOMESCO Finland

Nitrogen oxide therapy

3.4

10.3

132

ZXE03

NOMESCO Finland

Procedure duration 20 to 29 minutes

0.5

10.3

101

1691

F34.1

ICD-10 Finland

Dysthymia

0.5

10.3

1532

O40

ICD-10 Finland

Polyhydramnios

2.3

10.2

379

M01AB05

ATC

diclofenac; systemic, rectal

0.8

10.2

3117

30934

WX000

NOMESCO Finland

Monitoring vital functions without anesthesy

1.7

10.1

190

1007

O69.0

ICD-10 Finland

Labour and delivery complicated by prolapse of cord

+∞

10.0

6610B

ICD-9 Finland

Abnormality of forces of labour, Primary uterine inertia

+∞

10.0

O64.2

ICD-10 Finland

Obstructed labour due to face presentation

+∞

10.0

O69.2

ICD-10 Finland

Labour and delivery complicated by other cord entanglement, with compression

+∞

10.0

ZXA05

NOMESCO Finland

Left side

0.7

9.9

462

5607

X59

ICD-10 Finland

Exposure to unspecified factor

0.7

9.9

521

6212

MAB20

NOMESCO Finland

Failed external version

2.1

9.8

114

510

ZYC02

SPAT

0.4

9.7

1041

E10.9

ICD-10 Finland

Type 1 diabetes mellitus, Without complications

0.5

9.7

1481

O21.0

ICD-10 Finland

Mild hyperemesis gravidarum

2.1

9.7

103

444

NE1AG

NOMESCO Finland

MRI pelvimetry with high intensity magnet

2.6

9.6

251

O21

ICD-10 Finland

Excessive vomiting in pregnancy

2.2

9.6

386

O30.01

ICD-10 Finland

Twin pregnancy with a shared chorionic sac and a separate amniotic sac

6.2

9.6

P76

ICPC

Depressive disorder

0.7

9.5

279

3654

SPAT1263

SPAT

Sampling

1.2

9.5

2521

20562

N06AX03

ATC

mianserin; oral

0.4

9.4

976

N06AX26

ATC

vortioxetine; oral

0.6

9.4

200

2780

O28.3

ICD-10 Finland

Abnormal ultrasonic finding on antenatal screening of mother

2.4

9.4

283

Z00.4

ICD-10 Finland

General psychiatric examination, not elsewhere classified

0.7

9.4

466

5600

N05AB03

ATC

perphenazine; systemic, rectal

0.4

9.2

982

O34.3

ICD-10 Finland

Maternal care for cervical incompetence

3.2

9.2

130

Z46.9

ICD-10 Finland

Fitting and adjustment of unspecified device

4.6

9.2

R5110

NOMESCO Finland

Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it

0.6

9.2

143

2127

H01CA02

ATC

nafarelin; nasal

1.6

9.1

242

1412

65000

ICD-8 Finland

Delivery without mention of complication, Occipital presentation

0.7

9.1

306

3906

MWA00

NOMESCO Finland

Repair of wound dehiscence in obstetric surgery

6.4

9.0

R4190

NOMESCO Finland

Nutritional therapy

0.4

9.0

920

T89

ICPC

Diabetes insulin dependent

0.5

9.0

1181

WX402

NOMESCO Finland

General anaesthesia

0.8

9.0

529

6211

SPAT1273

SPAT

Structured assessment of psychoactive substance / tobacco use

1.5

9.0

295

1810

Z37.2

ICD-10 Finland

Twins, both liveborn

4.3

9.0

JH1AE

NOMESCO Finland

Anus structural ultrasound examination

19.7

8.9

W01

ICD-10 Finland

Fall on same level from slipping, tripping and stumbling

0.8

8.9

684

7759

XF400

NOMESCO Finland

ECG with 12 standard connections

0.7

8.8

202

2766

A10AB04

ATC

insulin lispro; parenteral (insulins and analog. for injection, fast-acting)

0.5

8.8

1030

XA800

NOMESCO Finland

Neuropsychological investigation

0.5

8.7

1003

F61.0

ICD-10 Finland

Mixed personality disorders

0.4

8.7

721

SPAT1383

SPAT

Extensive health check-up at 4 years of age

2.0

8.7

103

464

W82

ICPC

Abortion spontaneous

2.1

8.7

409

F33.9

ICD-10 Finland

Recurrent depressive disorder, unspecified

0.6

8.7

163

2329

IHZ02

SPAT

0.3

8.7

525

SPAT1250

SPAT

Comprehensive monitoring of chronic illness

0.7

8.7

331

4141

O90.2

ICD-10 Finland

Haematoma of obstetric wound

7.3

8.7

N06AB04

ATC

citalopram; systemic

0.8

8.7

789

8786

F60.3

ICD-10 Finland

Emotionally unstable personality disorder

0.4

8.6

657

EB1AA

SPAT

0.6

8.6

1564

F25.9

ICD-10 Finland

Schizoaffective disorder, unspecified

0.2

8.6

427

Z35.1

ICD-10 Finland

Supervision of pregnancy with history of abortive outcome

2.7

8.5

199

C09AA05

ATC

ramipril; oral

0.6

8.5

156

2237

ZXE02

NOMESCO Finland

Procedure duration 10 to 19 minutes

0.6

8.5

1581

SPAT1325

SPAT

Vaccination

1.2

8.5

1365

10613

A02BC02

ATC

pantoprazole; systemic

0.9

8.4

2616

26078

N81.2

ICD-10 Finland

Incomplete uterovaginal prolapse

1.8

8.4

146

759

F31.30

ICD-10 Finland

Bipolar disorder Depressive episode without somatic syndrome

0.4

8.3

881

N07BA03

ATC

varenicline; oral

0.6

8.2

111

1710

ICZ03

NOMESCO Finland

Participation in compiling a psychiatric treatment plan

0.5

8.2

1257

IEY05

NOMESCO Finland

Dedicated profession-specific psychiatric intervention, individual

0.5

8.2

1339

P06

ICPC

Sleep disturbance

0.7

8.2

323

4022

N02AA59

ATC

codeine, combinations excl. psycholeptics; systemic

0.8

8.2

1921

19590

M79.6

ICD-10 Finland

Pain in limb

0.8

8.2

1347

14146

N06AX21

ATC

duloxetine; oral

0.7

8.2

336

4155

L12

ICPC

Hand/finger symptom/complaint

0.7

8.1

423

5053

O90.9

ICD-10 Finland

Complication of the puerperium, unspecified

4.4

8.1

C08CA01

ATC

amlodipine; oral

0.7

8.1

328

4065

8839

FHL

Other measure in this category

82.0

8.1

8842

FHL

Peritoneal and vaginal wound revision

25.1

8.1

O81.0

ICD-10 Finland

Low forceps delivery

25.1

8.1

O03.4

ICD-10 Finland

Spontaneous abortion, Incomplete, without complication

1.6

8.0

202

1164

O41.9

ICD-10 Finland

Disorder of amniotic fluid and membranes, unspecified

3.0

8.0

134

65696

ICD-8 Finland

Delivery complicated by malpresentation of foetus, Complete or incomplete breech presentation

+∞

8.0

65310

ICD-8 Finland

Occipital presentation

+∞

8.0

65210

ICD-8 Finland

Occipital presentation

+∞

8.0

O74.5

ICD-10 Finland

Spinal and epidural anaesthesia-induced headache during labour and delivery

+∞

8.0

6534B

ICD-9 Finland

Disproportion, Foetopelvic disproportion[DISPROPORTIO FOETOPELVICA,SYNNYTYKSEN AIKANA]

+∞

8.0

O75.5

ICD-10 Finland

Delayed delivery after artificial rupture of membranes

+∞

8.0

SPAT1392

SPAT

Counselling and guidance related to couple relationship

2.2

8.0

331

ZXE13

NOMESCO Finland

Procedure duration 90 to 119 minutes

0.6

8.0

101

1579

LEF03

NOMESCO Finland

Posterior colporrpahy with sutures for primary rectocele

2.0

8.0

102

477

N07BB01

ATC

disulfiram; oral

0.5

8.0

905

HANKE

NOMESCO Finland

4.9

8.0

TLW14

NOMESCO Finland

ICSI

2.1

7.9

387

Z25.1

ICD-10 Finland

Need for immunization against influenza

1.6

7.9

207

1204

O30.00

ICD-10 Finland

Twin pregnancy with separate amniotic and chorionic sacs

3.0

7.9

138

N17

ICPC

Vertigo/dizziness

0.7

7.9

217

2867

N05BE01

ATC

buspirone; oral

0.4

7.8

754

WX725

NOMESCO Finland

Noninvasive ventilation

0.5

7.8

1029

R5140

NOMESCO Finland

Monitoring the use of the aid

0.6

7.8

101

1570

F31.9

ICD-10 Finland

Bipolar affective disorder, unspecified

0.5

7.8

1213

C03CA01

ATC

furosemide; systemic

0.7

7.7

191

2577

F33.1

ICD-10 Finland

Recurrent depressive disorder, current episode moderate

0.6

7.7

115

1728

A10AE05

ATC

insulin detemir; parenteral

0.5

7.6

1216

O44.0

ICD-10 Finland

Placenta praevia specified as without haemorrhage

2.2

7.6

290

N05AD01

ATC

haloperidol; systemic

0.3

7.6

494

W19

ICPC

Lactation symptom/complaint

2.5

7.6

203

F20.39

ICD-10 Finland

Undifferentiated schizophrenia UNS

0.0

7.6

205

C07AB07

ATC

bisoprolol; oral

0.8

7.6

801

8783

O26.9

ICD-10 Finland

Pregnancy-related condition, unspecified

2.4

7.5

221

F51.0

ICD-10 Finland

Nonorganic insomnia

0.8

7.5

600

6785

N05AF03

ATC

chlorprothixene; systemic

0.4

7.5

797

N06AA09

ATC

amitriptyline; systemic

0.6

7.5

146

2064

C09CA01

ATC

losartan; oral

0.7

7.5

253

3227

121

Kela drug reimbursment

Severe hypofunction of sexual glands

0.3

7.5

503

O99.6

ICD-10 Finland

Diseases of the digestive system complicating pregnancy, childbirth and the puerperium

2.0

7.4

406

B18.2

ICD-10 Finland

Chronic viral hepatitis C

0.2

7.4

341

F31.7

ICD-10 Finland

Bipolar affective disorder, currently in remission

0.4

7.4

723

MA2AE

SPAT

3.6

7.4

O28.8

ICD-10 Finland

Other abnormal findings on antenatal screening of mother

1.8

7.3

109

540

N05AE04

ATC

ziprasidone; systemic

0.2

7.3

357

LX1XE

NOMESCO Finland

Other gynecological ultrasound examination

1.6

7.3

165

930

F60.9

ICD-10 Finland

Personality disorder, unspecified

0.4

7.2

663

P99

ICPC

Psychological disorders other

0.6

7.2

1229

O71.9

ICD-10 Finland

Obstetric trauma, unspecified

72.9

7.1

H36.03

ICD-10 Finland

Proliferative diabetic retinopathy

0.0

7.1

190

F20.04

ICD-10 Finland

Paranoid schizophrenia with partial recurrence

0.0

7.1

160

O24.1

ICD-10 Finland

Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, non-insulin-dependent

2.6

7.1

172

6535B

ICD-9 Finland

Disproportion, Unusually large foetus causing disproportion[EPÄTAVALLISEN ISO SIKIÖ (YLI 4500 G), SYNN AIKANA]

+∞

7.0

6631A

ICD-9 Finland

Umbilical cord complications, Cord around neck, with compression

+∞

7.0

6643B

ICD-9 Finland

Trauma to perineum and vulva during delivery, Fourth-degree perineal laceration

+∞

7.0

O71.0

ICD-10 Finland

Rupture of uterus before onset of labour

+∞

7.0

KMAK

NOMESCO Finland

0.9

7.0

3266

31817

IBZ01

NOMESCO Finland

Profession-specific psychiatric evaluation

0.4

7.0

699

8802

FHL

Forceps delivery

12.1

7.0

C10AA01

ATC

simvastatin; oral

0.7

7.0

285

3526

F31.4

ICD-10 Finland

Bipolar affective disorder, current episode severe depression without psychotic symptoms

0.4

6.9

625

P74

ICPC

Anxiety disorder/anxiety state

0.7

6.9

170

2293

SPAT1311

SPAT

Counselling and guidance related to occupational health

1.5

6.9

208

1258

M25.5

ICD-10 Finland

Pain in joint

0.8

6.9

1166

12240

G03DC03

ATC

lynestrenol; oral

0.5

6.9

1060

Z3231

NOMESCO Finland

Registered nurse

0.8

6.8

865

9321

O34.1

ICD-10 Finland

Maternal care for tumour of corpus uteri

2.8

6.8

134

Z01.0

ICD-10 Finland

Examination of eyes and vision

0.8

6.8

409

4792

O03.3

ICD-10 Finland

Spontaneous abortion, Incomplete, with other and unspecified complications

2.7

6.8

140

GD1UA

NOMESCO Finland

Thorax X-ray examination outside radiological department

0.6

6.8

126

1801

TAB20

NOMESCO Finland

Epidural puncture

3.0

6.8

114

LC2HE

NOMESCO Finland

Hystero-salpingography with ultrasound

1.3

6.8

405

2783

F31.8

ICD-10 Finland

Other bipolar affective disorders

0.5

6.8

954

R05

ICPC

Cough

0.8

6.7

897

9625

O92.4

ICD-10 Finland

Hypogalactia

6.2

6.7

TKC20

NOMESCO Finland

Catheterisation of bladder

1.6

6.7

153

863

L16

ICPC

Ankle symptom/complaint

0.7

6.7

269

3335

MBB10

NOMESCO Finland

Packing of delivered uterus

10.9

6.7

H04AA01

ATC

glucagon; nasal, parenteral

0.5

6.7

915

ZXE06

NOMESCO Finland

Procedure duration 50 to 59 minutes

0.6

6.6

133

1868

EBA05

NOMESCO Finland

Complicated extraction of tooth

0.8

6.6

603

6726

ICB01

NOMESCO Finland

Psychiatric treatment plan, standard

0.6

6.6

1179

LEF13

NOMESCO Finland

Colpoperineoplasty and vaginal hysterectomy

2.0

6.6

356

Z31.2

ICD-10 Finland

In vitrofertilization

2.0

6.6

356

S18

ICPC

Laceration/cut

0.8

6.5

1210

12619

D25.9

ICD-10 Finland

Leiomyoma of uterus, unspecified

0.7

6.5

249

3112

XF402

NOMESCO Finland

ECG with work load test

0.6

6.5

1224

E10.2

ICD-10 Finland

Type 1 diabetes mellitus, With renal complications

0.1

6.5

225

SPAT1262

SPAT

Handing over of treatment supplies

1.3

6.5

485

3440

N06CA01

ATC

amitriptyline and psycholeptics; systemic

0.7

6.5

200

2589

P29

ICPC

Psychological sympt/compl other

0.7

6.5

258

3207

A46

ICD-10 Finland

Erysipelas

0.6

6.5

133

1858

N03AE01

ATC

clonazepam; systemic

0.6

6.5

1440

MAG96

NOMESCO Finland

Other breech delivery

6.3

6.5

R60.9

ICD-10 Finland

Oedema, unspecified

0.5

6.4

852

E66.01

ICD-10 Finland

Obesity due to excess calories

1.3

6.4

479

3405

O26

ICD-10 Finland

Maternal care for other conditions predominantly related to pregnancy

9.9

6.4

WX110

NOMESCO Finland

Local anesthesy

0.9

6.4

4037

38667

A77

ICPC

Viral disease other/NOS

1.4

6.4

244

1553

N89.8

ICD-10 Finland

Other specified noninflammatory disorders of vagina

2.3

6.3

231

F33.10

ICD-10 Finland

Recurrent depression, moderate episode without somatic syndrome

0.7

6.3

267

3283

R1210

NOMESCO Finland

Medical assessment of need and possibilities to rehabilitation

0.2

6.3

294

F90.0

ICD-10 Finland

Disturbance of activity and attention

0.6

6.2

117

1665

A02BC01

ATC

omeprazole; systemic

1.2

6.2

1063

8295

A10AD01

ATC

insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)

0.3

6.2

404

SPAT1284

SPAT

Extensive health certificate

0.6

6.2

1086

188

Kela drug reimbursment

Psychosis requiring demanding treatment

0.2

6.2

255

CKD05

NOMESCO Finland

Puncture of vitreous body with injection of medication

0.2

6.2

309

IDY03

NOMESCO Finland

Systematic individual therapy, cognitive-behavioural

0.6

6.2

116

1651

N02AE01

ATC

buprenorphine; parenteral, sublingual, transdermal

0.6

6.2

107

1550

P15

ICPC

Chronic alcohol abuse

0.4

6.2

488

Z50.9

ICD-10 Finland

Care involving use of rehabilitation procedure, unspecified

0.5

6.1

878

J01DB01

ATC

cefalexin; oral

1.2

6.1

5057

44264

6524B

ICD-9 Finland

Malposition and malpresentation of foetus, Face or brow presentation[HABITUS DEFLEXIONIS,SYNNYTYKSEN AIKANA]

+∞

6.0

6690A

ICD-9 Finland

Other complications of labour and delivery, not elsewhere classified, Maternal distress

+∞

6.0

6671A

ICD-9 Finland

Retained placenta or membranes, without haemorrhage, Retained portions of placenta or membranes, without haemorrhage

+∞

6.0

6522A

ICD-9 Finland

Malposition and malpresentation of foetus, Breech presentation without mention of version[PRAESENTATIO CLUNIUM,RASKAUDEN AIKANA]

+∞

6.0

P98

ICPC

Psychosis NOS/other

0.2

6.0

233

EB1AA

NOMESCO Finland

Tooth X-ray examination

0.9

6.0

2851

27861

F41.1

ICD-10 Finland

Generalized anxiety disorder

0.7

6.0

245

3028

NAME	O15_DELIV_PERIN_LACER
CONTROL_EXCLUDE	O15_COMPLIC_LAB_DELIV
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX	2
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	O70
HD_ICD_9	664
HD_ICD_8	6603
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	O70
COD_ICD_9	664
COD_ICD_8	6603
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Parameter	HR [95% CI]	p-value
O15_DELIV_PERIN_LACER	0.416 [0.33, 0.52]	< 0.001
Birth year	0.993 [0.98, 1.0]	0.094

N-year risk	Females	Males
1	0.022%	No data
5	0.178%	No data
10	0.506%	No data
15	1.004%	No data
20	1.809%	No data

Perineal laceration during delivery

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints