Other and unspecified paralytic syndromes

G6_PARALOTHUNS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G83.8, G83.9
  • Hospital discharge: ICD-9 344
  • Hospital discharge: ICD-8 3440[8-9]
  • Cause of death: ICD-10 G83.8, G83.9
  • Cause of death: ICD-9 344
  • Cause of death: ICD-8 3440[8-9]

2 out of 7 registries used, show all original rules.

540

4. Check minimum number of events

None

540

5. Include endpoints

None

540

6. Filter based on genotype QC (FinnGen only)

520

Control definitions (FinnGen only)

Control exclude
G6_CPETAL

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5694 2528 3080
Only index persons 4141 1913 2228
Unadjusted period prevalence (%)
Whole population 0.08 0.07 0.09
Only index persons 0.08 0.07 0.09
Median age at first event (years)
Whole population 46.76 48.42 45.00
Only index persons 38.07 42.26 34.48

-FinnGen-

Key figures

All Female Male
Number of individuals 520 285 235
Unadjusted period prevalence (%) 0.10 0.10 0.11
Median age at first event (years) 48.58 44.90 53.05

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
540
Matched controls
5400
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G83.9
ICD-10 Finland
Paralytic syndrome, unspecified
4583.5
262.8
232
*
G83.8
ICD-10 Finland
Other specified paralytic syndromes
+∞
156.0
142
*
34408
ICD-8 Finland
Other cerebral paralysis, Alia definita
+∞
91.3
85
*
34409
ICD-8 Finland
Other cerebral paralysis, Unspecified
+∞
67.1
63
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
8.5
63.4
89
122
AA1AD
NOMESCO Finland
CT of head and brain
4.1
57.2
245
901
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
6.0
54.3
111
225
N03AX14
ATC
levetiracetam; systemic
11.0
47.6
53
53
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
12.2
44.6
46
41
N18
ICPC
Paralysis/weakness
16.2
40.3
35
23
R56.8
ICD-10 Finland
Other and unspecified convulsions
6.3
37.4
67
118
G81.9
ICD-10 Finland
Hemiplegia, unspecified
381.6
36.4
36
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.7
36.2
147
500
G40.9
ICD-10 Finland
Epilepsy, unspecified
7.4
35.4
54
80
R4120
NOMESCO Finland
Occupational therapy
5.2
34.8
78
169
A28
ICPC
Limited function/disability NOS
3.6
34.4
145
504
N03AG01
ATC
valproic acid; systemic, rectal
4.9
31.7
76
174
3449X
ICD-9 Finland
Other paralytic syndromes, Paralysis, unspecified
+∞
31.6
30
*
T36
ICD-10 Finland
Poisoning by systemic antibiotics
6.3
31.2
55
95
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.1
31.0
96
269
L28
ICPC
Limited function/disability (L)
3.4
30.8
141
513
N03AX12
ATC
[U] gabapentin; oral
3.4
30.2
138
501
N03AF02
ATC
oxcarbazepine; oral
6.9
29.9
48
75
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
9.6
29.8
36
40
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.1
28.6
90
254
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
3.8
27.9
96
289
R4110
NOMESCO Finland
Physiotherapy
2.8
27.0
199
938
R51.80
ICD-10 Finland
Headache
3.1
26.6
140
549
XA800
NOMESCO Finland
Neuropsychological investigation
5.6
26.0
52
101
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
4.2
25.9
75
199
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.1
24.4
122
463
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
4.6
24.2
62
149
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
4.0
24.0
74
205
XF400
NOMESCO Finland
ECG with 12 standard connections
3.1
24.0
122
467
78159
ICD-8 Finland
Other symptoms referable to nervous system and special senses, Laesio loquendi alia sive NUD
91.0
23.9
26
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.8
23.8
82
246
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
8.6
23.7
31
38
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.8
23.6
81
242
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.2
23.6
110
400
TAB00
NOMESCO Finland
Lumbar puncture
4.9
23.2
54
120
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
6.2
23.1
41
71
N03AF01
ATC
carbamazepine; oral, rectal
4.7
22.6
55
127
N05AA02
ATC
levomepromazine; systemic
5.3
22.2
47
96
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
6.3
21.5
37
62
R20.2
ICD-10 Finland
Paraesthesia of skin
3.9
21.5
67
187
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.9
21.3
117
465
R42
ICD-10 Finland
Dizziness and giddiness
2.6
21.1
157
731
N03AX16
ATC
[U] pregabalin
2.6
20.9
161
761
Z3226
NOMESCO Finland
Physiotherapist
2.7
20.5
131
564
N03AX09
ATC
lamotrigine; oral
4.3
20.3
55
138
SPAT1229
SPAT
Assessment of need for aid
4.0
20.2
62
171
K90
ICPC
Stroke/cerebrovascular accident
7.1
18.9
29
43
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.8
18.7
115
483
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.5
18.7
153
740
TKC20
NOMESCO Finland
Catheterisation of bladder
3.7
18.4
62
182
N05CD07
ATC
temazepam; oral
3.0
18.4
90
334
R11
ICD-10 Finland
Nausea and vomiting
3.2
18.1
77
263
R52.2
ICD-10 Finland
Other chronic pain
4.8
18.1
42
93
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
3.5
17.9
66
206
A06AD11
ATC
lactulose; oral
2.8
17.8
103
419
N05AH04
ATC
quetiapine; oral
2.5
17.6
133
617
UKC02
NOMESCO Finland
Cystoscopy
2.8
17.6
106
440
R07.4
ICD-10 Finland
Chest pain, unspecified
2.3
17.3
178
947
S06.0
ICD-10 Finland
Concussion
2.9
17.1
88
335
R53
ICD-10 Finland
Malaise and fatigue
2.3
17.1
169
884
N03AE01
ATC
clonazepam; systemic
3.9
16.8
52
144
N05BA01
ATC
diazepam; systemic, rectal
2.7
16.5
100
415
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.9
16.5
50
136
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
6.8
16.3
26
40
N02AA05
ATC
oxycodone; systemic
2.5
16.3
118
535
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
16.3
143
709
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
6.2
16.2
28
47
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.6
16.2
110
484
N06AB04
ATC
citalopram; systemic
2.4
16.1
142
705
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.2
16.0
192
1083
M03BX01
ATC
baclofen; systemic
7.1
15.8
24
35
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.7
15.8
93
380
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.6
15.3
53
158
N02BF01
ATC
gabapentin; oral
3.2
15.0
64
218
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
4.0
14.8
44
118
U05
ICPC
Urination problems other
4.0
14.8
44
118
U07
ICPC
Urine symptom/complaint other
3.5
14.8
54
167
A04
ICPC
Weakness/tiredness general
2.6
14.8
100
438
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.1
14.7
67
238
N28
ICPC
Limited function/disability (N)
13.0
14.5
25
20
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
4.7
14.4
34
76
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.4
14.4
56
180
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
10.9
14.4
27
26
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
13.9
14.3
24
18
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
14.3
219
1345
R33
ICD-10 Finland
Retention of urine
3.1
14.1
61
210
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.6
14.0
48
142
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
13.9
257
1683
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.6
13.9
47
138
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.6
13.8
47
139
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
4.8
13.7
31
67
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.5
13.6
50
155
WX892
NOMESCO Finland
Monitored bed care
3.2
13.6
57
192
G83.4
ICD-10 Finland
Cauda equina syndrome
143.5
13.5
14
*
N05AF03
ATC
chlorprothixene; systemic
4.9
13.5
30
64
N06AX11
ATC
mirtazapine; oral
2.0
13.2
207
1274
Z2446
NOMESCO Finland
Social worker
3.1
13.2
57
196
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
13.1
208
1286
L17
ICPC
Foot/toe symptom/complaint
2.1
13.0
169
970
N02AX02
ATC
tramadol; systemic, rectal
2.0
13.0
248
1631
H53.2
ICD-10 Finland
Diplopia
4.8
13.0
30
66
N05AH03
ATC
olanzapine; systemic
3.2
12.9
55
187
Z2445
NOMESCO Finland
Psychologist
3.8
12.8
40
111
R1250
NOMESCO Finland
Evaluation of functional capability
5.7
12.7
24
44
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
12.6
215
1357
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
5.4
12.6
25
48
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.9
12.6
65
247
3141A
ICD-9 Finland
Hyperkinetic syndrome of childhood, Hyperkinesis with developmental delay
133.0
12.5
13
*
W19
ICD-10 Finland
Unspecified fall
2.8
12.4
69
273
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.8
12.4
69
273
N05AX12
ATC
aripiprazole; systemic
3.9
12.3
37
100
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.5
12.1
86
383
N88
ICPC
Epilepsy
21.9
12.1
17
8
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.7
11.8
68
273
G44.2
ICD-10 Finland
Tension-type headache
2.4
11.8
94
441
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.2
11.8
122
639
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
5.7
11.7
22
40
A03FA01
ATC
metoclopramide; systemic, rectal
2.1
11.7
136
745
F44.9
ICD-10 Finland
Dissociative [conversion] disorder, unspecified
23.5
11.6
16
7
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
9.6
11.6
23
25
R4190
NOMESCO Finland
Nutritional therapy
3.9
11.6
35
95
78151
ICD-8 Finland
Other symptoms referable to nervous system and special senses, Aphasia
+∞
11.5
11
*
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
+∞
11.5
11
*
G82.2
ICD-10 Finland
Paraplegia, unspecified
122.5
11.5
12
*
F44.4
ICD-10 Finland
Dissociative motor disorders
122.5
11.5
12
*
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
3.2
11.5
46
151
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
5.3
11.4
23
45
KH1AD
NOMESCO Finland
CT of urinary organs
4.7
11.3
26
57
ZY010
NOMESCO Finland
Hospital outpatient
3.3
11.3
44
142
F61.0
ICD-10 Finland
Mixed personality disorders
5.7
11.3
21
38
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.9
11.2
33
88
NA1AD
NOMESCO Finland
Cervical spine CT examination
3.5
11.2
40
122
X58
ICD-10 Finland
Exposure to other specified factors
2.3
11.1
97
473
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.2
11.1
110
565
N06AX16
ATC
venlafaxine; oral
2.3
11.1
94
453
J46
ICD-10 Finland
Status asthmaticus
5.0
11.1
24
50
M54.1
ICD-10 Finland
Radiculopathy
3.8
11.0
34
94
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
4.4
10.9
28
67
G35
ICD-10 Finland
Multiple sclerosis
8.5
10.9
23
28
G43.9
ICD-10 Finland
Migraine, unspecified
3.1
10.8
48
167
C03CA01
ATC
furosemide; systemic
2.0
10.8
165
993
Z3231
NOMESCO Finland
Registered nurse
2.0
10.8
163
977
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.0
10.8
51
184
R39.1
ICD-10 Finland
Other difficulties with micturition
4.7
10.8
25
55
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.4
10.8
81
370
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
28.7
10.8
14
5
A29
ICPC
General symptom/complaint other
2.3
10.7
85
398
N05AX08
ATC
risperidone; systemic
2.6
10.6
65
269
F43.1
ICD-10 Finland
Post-traumatic stress disorder
4.6
10.6
25
56
A46
ICD-10 Finland
Erysipelas
2.3
10.6
88
420
R52.9
ICD-10 Finland
Pain, unspecified
2.5
10.5
69
296
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
+∞
10.4
10
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.1
10.4
113
602
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
10.9
10.3
19
18
N30.0
ICD-10 Finland
Acute cystitis
2.2
10.3
93
459
G40.89
ICD-10 Finland
Other epilepsy
19.2
10.3
15
8
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.6
10.3
64
267
F41.09
ICD-10 Finland
UNS Panic Syndrome
4.4
10.2
26
62
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.3
10.2
87
420
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
10.1
161
979
R55
ICD-10 Finland
Syncope and collapse
2.5
10.1
71
314
A01
ICPC
Pain general/multiple sites
2.6
10.1
62
257
XKD00
NOMESCO Finland
Uroflowmetry
2.3
10.0
83
395
SPAT1254
SPAT
Administration of medicine
2.3
9.9
87
424
IGY99
NOMESCO Finland
Other psychiatric treatment contact
4.8
9.8
22
47
78020
ICD-8 Finland
Certain symptoms referable to nervous system and special senses, Convulsions
9.8
9.8
19
20
N99
ICPC
Neurological disease other
9.8
9.8
19
20
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.4
9.8
74
338
B01AB05
ATC
enoxaparin; parenteral
1.9
9.8
169
1055
M79.6
ICD-10 Finland
Pain in limb
1.8
9.7
230
1580
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.8
9.6
49
185
R60.0
ICD-10 Finland
Localized oedema
2.3
9.6
74
342
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.1
9.5
106
568
P15
ICPC
Chronic alcohol abuse
4.1
9.4
26
66
Z2221
NOMESCO Finland
Medical doctor
1.9
9.4
158
975
N06AX21
ATC
duloxetine; oral
2.3
9.4
75
351
34400
ICD-8 Finland
Other cerebral paralysis, Hemiplegia NUD
+∞
9.4
9
*
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.2
9.4
92
469
A11
ICPC
Chest pain NOS
2.6
9.4
55
223
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
4.0
9.3
27
71
C07AB07
ATC
bisoprolol; oral
1.8
9.3
250
1775
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.5
9.3
32
95
P29
ICPC
Psychological sympt/compl other
2.7
9.3
50
194
R06.0
ICD-10 Finland
Dyspnoea
1.9
9.3
156
963
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
4.4
9.2
23
54
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
9.2
145
876
B01AC04
ATC
clopidogrel; oral
2.1
9.2
93
480
XX1XW
NOMESCO Finland
Extensive written report from radiologist
4.9
9.1
20
42
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.9
9.1
152
936
N03AX18
ATC
lacosamide; systemic
15.9
9.1
14
9
N03AX11
ATC
topiramate; oral
4.0
9.1
26
68
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
9.0
143
865
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.1
9.0
39
134
F29
ICD-10 Finland
Unspecified nonorganic psychosis
3.3
8.9
33
103
A02BC02
ATC
pantoprazole; systemic
1.8
8.9
359
2848
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
8.8
76
367
Z02.7
ICD-10 Finland
Issue of medical certificate
2.7
8.8
50
199
K59.09
ICD-10 Finland
Constipation, unspecified
2.8
8.8
44
164
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.6
8.8
29
84
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.4
8.8
64
288
H02AB09
ATC
hydrocortisone; systemic
4.4
8.7
22
52
N30.9
ICD-10 Finland
Cystitis, unspecified
2.9
8.7
43
159
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.5
8.7
59
257
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
4.7
8.7
20
44
183
Kela drug reimbursment
Lamotrigin and topiramate
8.4
8.6
18
22
SPAT1216
SPAT
Assessment of functional ability
2.1
8.6
87
448
M54.4
ICD-10 Finland
Lumbago with sciatica
2.0
8.6
105
580
G41.9
ICD-10 Finland
Status epilepticus, unspecified
20.4
8.5
12
6
Z71.8
ICD-10 Finland
Other specified counselling
1.8
8.5
171
1111
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
3.9
8.4
25
67
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.8
8.4
44
168
N05AN01
ATC
lithium; oral
4.1
8.4
23
58
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
3.9
8.3
24
63
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
3.9
8.3
24
63
N06AA09
ATC
amitriptyline; systemic
2.4
8.3
57
249
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.6
8.3
48
193
N17
ICPC
Vertigo/dizziness
2.3
8.3
70
335
P99
ICPC
Psychological disorders other
3.8
8.3
25
68
J01MA02
ATC
ciprofloxacin; systemic
1.7
8.2
208
1439
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
2.9
8.2
40
147
ZXD05
NOMESCO Finland
Urgent procedure
1.8
8.2
169
1104
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
3.4
8.2
29
88
WX110
NOMESCO Finland
Infiltration anesthesia
1.8
8.2
378
3077
H02AB06
ATC
prednisolone; systemic
1.7
8.1
254
1861
N86
ICPC
Multiple sclerosis
17.5
8.1
12
7
JN3AD
NOMESCO Finland
Abdominal CT examination
2.3
8.1
67
319
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
22.4
8.0
11
5
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
7.4
8.0
18
25
N02BE01
ATC
paracetamol; systemic, rectal
2.1
8.0
474
4156
ZXD35
NOMESCO Finland
Usual procedure
3.8
8.0
24
65
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
4.7
7.9
18
39
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
4.7
7.9
18
39
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.3
7.9
61
281
S22.3
ICD-10 Finland
Fracture of rib
2.6
7.9
48
198
TPH07
NOMESCO Finland
Cathetrisation of artery
2.3
7.9
65
308
U08
ICPC
Urinary retention
7.1
7.8
18
26
N05CD08
ATC
midazolam; nasal, systemic
4.3
7.8
20
48
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
3.6
7.8
25
71
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.4
7.8
57
257
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.2
7.8
66
317
R52.0
ICD-10 Finland
Acute pain
3.5
7.8
27
81
H53.1
ICD-10 Finland
Subjective visual disturbances
2.6
7.7
45
182
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
7.6
172
1148
G40
ICD-10 Finland
Epilepsy
8.2
7.6
16
20
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.3
7.6
63
299
SPAT1167
SPAT
Insertion of urinary catheter
3.9
7.6
22
58
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.4
7.6
56
253
S29
ICPC
Skin symptom/complaint other
1.9
7.6
102
582
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
7.6
105
605
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.2
7.5
65
314
R03BB04
ATC
tiotropium bromide; inhalant
2.3
7.5
58
267
S63.6
ICD-10 Finland
Sprain and strain of finger(s)
3.2
7.5
29
93
ZXA00
NOMESCO Finland
Right side
1.8
7.5
140
885
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
4.5
7.5
18
41
T78.4
ICD-10 Finland
Allergy, unspecified
3.1
7.5
31
104
K59.0
ICD-10 Finland
Constipation
2.7
7.5
39
149
34099
ICD-8 Finland
Multiple sclerosis
81.2
7.4
8
*
3001A
ICD-9 Finland
Neurotic disorders, Hysteria[KONVERSIOHÄIRIÖ]
81.2
7.4
8
*
7803A
ICD-9 Finland
General symptoms, Convulsions
8.5
7.4
15
18
T90.5
ICD-10 Finland
Sequelae of intracranial injury
8.5
7.4
15
18
RS220, ,
NOMESCO Finland
8.5
7.4
15
18
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.3
7.3
54
244
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
9.5
7.3
14
15
G83.2
ICD-10 Finland
Monoplegia of upper limb
+∞
7.3
7
*
I10
ICD-10 Finland
Essential (primary) hypertension
1.6
7.3
296
2296
Z43.5
ICD-10 Finland
Attention to cystostomy
16.0
7.3
11
7
WW200
NOMESCO Finland
Immunization
4.0
7.2
20
51
C08CA01
ATC
amlodipine; oral
1.7
7.2
187
1295
X59
ICD-10 Finland
Exposure to unspecified factor
1.9
7.2
106
623
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.8
7.1
36
135
C09AA05
ATC
ramipril; oral
1.8
7.1
130
815
R5110, ,
SPAT
2.7
7.1
38
147
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.9
7.1
32
113
M54.5
ICD-10 Finland
Low back pain
1.7
7.0
193
1353
L12
ICPC
Hand/finger symptom/complaint
1.9
7.0
90
504
SPAT1285
SPAT
Provision of consultation response
2.9
7.0
33
119
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.4
7.0
49
216
XF600
NOMESCO Finland
Bloodpressure measurement
2.6
7.0
41
166
XCK00
NOMESCO Finland
Perimetry
2.7
7.0
39
154
R51.81
ICD-10 Finland
Facial pain NOS
4.5
7.0
17
39
XKC03
NOMESCO Finland
Water cystometry
3.8
7.0
21
57
F34.1
ICD-10 Finland
Dysthymia
3.0
7.0
30
103
WZC00
NOMESCO Finland
Treatment plan or consultation
1.7
6.9
181
1252
W00
ICD-10 Finland
Fall on same level involving ice and snow
2.1
6.9
65
325
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.4
6.9
25
77
J01EA01
ATC
trimethoprim; systemic
1.8
6.9
136
871
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
6.9
112
678
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
6.8
6.9
16
24
TKC22
NOMESCO Finland
Catheterisation instruction
4.4
6.8
17
40
204
Kela drug reimbursment
Leukemia lymphatica
3.4
6.8
24
73
AA1BD
NOMESCO Finland
Extensive CT of head and brain
4.0
6.8
19
49
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
7.3
6.7
15
21
H03AA01
ATC
levothyroxine sodium; systemic
1.8
6.7
121
754
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.5
6.7
43
182
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
3.8
6.7
20
54
R51
ICD-10 Finland
Headache
2.7
6.7
35
134
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
3.2
6.7
26
84
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.6
6.7
38
152
X57
ICD-10 Finland
Unspecified privation
4.1
6.7
18
45
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
6.0
6.7
17
29
NG4AA
NOMESCO Finland
Lower leg X-ray examination
3.3
6.6
25
79
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
6.6
109
661
F60.7
ICD-10 Finland
Dependent personality disorder
12.4
6.6
11
9
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.1
6.6
62
310
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.6
6.6
37
147
F10.09
ICD-10 Finland
Alcohol intoxication UNS
3.9
6.6
19
50
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
10.2
6.6
12
12
ZXE00
NOMESCO Finland
One hour or less
1.6
6.6
204
1471
R50.9
ICD-10 Finland
Fever, unspecified
1.9
6.5
85
478
R07.3
ICD-10 Finland
Other chest pain
2.1
6.5
63
318
WX882
NOMESCO Finland
High dependency care
3.7
6.5
20
55
S62.6
ICD-10 Finland
Fracture of other finger
2.9
6.5
30
107
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
5.4
6.5
18
34
F05.9
ICD-10 Finland
Delirium, unspecified
5.8
6.5
17
30
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
4.0
6.5
18
46
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.4
6.5
23
70
WX402
NOMESCO Finland
General anaesthesia
1.8
6.5
106
642
A02BC03
ATC
lansoprazole; oral
1.7
6.5
152
1020
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.7
6.4
33
125
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
70.7
6.4
7
*
F70.9
ICD-10 Finland
Mild mental retardation, Without mention of impairment of behaviour
70.7
6.4
7
*
R31
ICD-10 Finland
Unspecified haematuria
2.2
6.4
55
265
Z3229
NOMESCO Finland
Other healthcare associate professional
2.3
6.4
49
225
SPAT1243
SPAT
Psychiatric/psychological examination
3.8
6.4
19
51
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.0
6.4
77
422
A99
ICPC
Disease/condition unspecnature/site
2.3
6.4
50
232
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
3.5
6.3
21
61
XKD06
NOMESCO Finland
Physiologic investigation of micturition
3.5
6.3
21
61
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
5.6
6.3
17
31
ZY000
NOMESCO Finland
Hospital inpatient
6.1
6.3
16
27
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.9
6.3
30
109
N05BA09
ATC
clobazam; oral
11.2
6.3
11
10
L29
ICPC
Musculoskeletal sympt/complt other
2.3
6.3
48
220
R25.2
ICD-10 Finland
Cramp and spasm
3.9
6.3
18
47
Z72.8
ICD-10 Finland
Other problems related to lifestyle
18.3
6.3
9
5
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.4
6.3
45
201
3430A
ICD-9 Finland
Infantile cerebral palsy, Diplegic
+∞
6.3
6
*
G83.1
ICD-10 Finland
Monoplegia of lower limb
+∞
6.3
6
*
34300
ICD-8 Finland
Cerebral spastic infantile paralysis, Hemiplegia spastica
+∞
6.3
6
*
34308
ICD-8 Finland
Cerebral spastic infantile paralysis, Alia definita
+∞
6.3
6
*
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
+∞
6.3
6
*
G81.1
ICD-10 Finland
Spastic hemiplegia
+∞
6.3
6
*
XA402
NOMESCO Finland
ENMG
3.8
6.2
19
52
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.6
6.2
36
145
IAB07
NOMESCO Finland
Consultation concerning a patient with self-harm intention
27.0
6.2
8
*
R13
ICD-10 Finland
Dysphagia
2.4
6.2
41
176
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
5.1
6.2
18
36
N05BA04
ATC
oxazepam; oral
1.7
6.2
143
953
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.5
6.2
39
164
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
3.2
6.1
24
78
SPAT1255
SPAT
Intravenous administration of medicine
2.5
6.1
38
159
B01AA03
ATC
warfarin; systemic
1.8
6.0
93
552
WX002
NOMESCO Finland
Sedation and analgesia
1.8
6.0
100
607
L03
ICPC
Low back symptom/complaint
1.7
6.0
142
951
N29
ICPC
Neurological sympt/complt other
5.7
6.0
16
29
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
6.0
245
1872
S21
ICPC
Skin texture symptom/complaint
1.9
6.0
75
416

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
285
1230
3.79
51.43
4.2
2.0
234.70
219.64
u/l
0.08
275
1166
50
73
7.45
33.21
1.2
1.2
—
—
—
0
0
322
1826
2.89
31.71
9.0
5.8
1.20
1.21
mmol/l
1.14
307
1675
115
376
3.62
29.63
3.6
2.4
28.82
45.13
u/l
0.73
96
310
53
94
6.14
29.23
1.3
1.2
459.09
411.36
mg/l
0.62
47
89
30
27
11.71
28.68
1.2
1.0
—
—
—
0
0
49
82
6.47
28.61
1.2
1.2
3.72
3.74
mmol/l
0.05
42
75
337
2031
2.75
28.27
9.0
6.5
1.21
1.21
mmol/l
0.62
307
1726
33
39
8.95
26.02
1.2
1.4
—
—
—
0
0
234
1225
2.61
25.41
5.1
3.7
7.40
7.40
ph
0.12
37
227
150
634
2.89
24.75
4.8
2.9
1.95
2.26
e6/l
0.24
82
330
46
86
5.75
23.96
1.3
1.2
4.54
5.51
e6/l
0.10
26
70
46
86
5.75
23.96
1.3
1.3
301.79
214.66
e6/l
0.18
29
73
295
1763
2.48
23.65
5.6
4.6
35.58
35.94
g/l
0.52
278
1659
168
771
2.71
23.53
5.0
3.3
456.38
305.93
ng/l
0.20
122
588
233
1256
2.50
23.33
5.8
3.1
48.30
100.89
e6/l
0.46
184
957
368
2448
2.58
23.16
8.5
4.6
6.54
6.71
mmol/l
0.89
358
2287
307
1898
2.43
22.41
16.0
13.5
1.21
1.25
inr
0.30
85
556
60
150
4.38
22.28
2.9
2.4
20.05
21.28
s
0.97
55
134
147
647
2.75
22.19
4.1
3.2
0.81
0.82
mmol/l
0.37
142
614
207
1087
2.47
21.59
5.6
4.0
—
—
—
0
0
119
478
2.91
21.27
3.5
2.9
8.10
7.86
umol/l
0.04
103
417
253
1464
2.37
21.09
6.7
3.6
79.91
100.97
e6/l
0.23
191
1021
206
1091
2.44
20.97
5.6
2.9
—
—
—
0
0
147
667
2.65
20.74
4.4
2.7
0.63
1.09
e6/l
2.17
78
363
388
2735
2.49
20.11
7.7
4.2
4824.43
1730.88
e6/l
—
7
50
246
1443
2.29
19.45
4.9
3.2
31.37
31.23
u/l
0.03
233
1377
329
2194
2.28
18.85
8.2
6.0
9.78
11.21
umol/l
2.26
320
2073
205
1125
2.33
18.85
5.8
3.0
0.32
0.39
e6/l
0.31
159
837
215
1216
2.28
18.29
5.5
3.0
—
—
—
0
0
233
1395
2.18
16.91
3.8
3.3
2.34
2.35
mmol/l
0.59
211
1252
164
851
2.33
16.88
4.3
2.6
6.47
5.88
e6/l
0.16
157
765
106
449
2.69
16.86
7.1
7.5
0.52
1.12
mmol/l
0.62
88
365
85
329
2.88
16.01
11.2
8.9
—
—
—
0
0
157
823
2.28
15.61
4.6
2.9
549.37
550.35
mosm/kgh2o
0.02
145
702
116
534
2.49
15.46
5.2
5.4
1.07
1.04
mmol/l
0.33
109
493
312
2166
2.04
14.53
9.2
5.5
0.58
0.57
e9/l
0.28
271
1889
312
2171
2.04
14.38
9.2
5.5
0.04
0.04
e9/l
0.13
270
1896
170
950
2.15
14.24
2.6
1.8
1.02
1.17
mg/l
0.35
141
715
81
326
2.75
14.11
2.9
2.8
10.37
10.40
g/l
0.02
75
295
319
2252
2.02
13.94
9.5
5.8
0.18
0.19
e9/l
0.30
277
1992
297
2051
2.00
13.75
8.1
6.0
—
—
—
0
0
66
241
2.98
13.74
2.7
2.8
—
—
—
0
0
183
1066
2.08
13.65
11.8
6.5
—
—
—
0
0
314
2222
1.99
13.43
9.3
5.6
2.05
1.97
e9/l
0.15
281
1989
87
373
2.59
13.34
7.7
3.9
5.93
5.81
kpa
0.44
82
361
343
2511
2.00
13.20
14.4
8.9
4.01
4.08
e9/l
0.25
304
2204
248
1633
1.96
12.94
2.3
1.9
85.72
95.76
pmol/l
3.09
154
888
80
334
2.64
12.93
5.1
6.4
9.67
9.16
mmol/l
0.17
73
316
41
116
3.74
12.80
4.8
3.0
—
—
—
0
0
415
3276
2.15
12.69
11.7
7.3
86.86
76.98
u/l
2.17
402
3087
85
369
2.55
12.68
7.8
3.9
1.74
1.83
mmol/l
0.08
71
294
58
209
2.99
12.34
6.7
10.4
23.69
24.43
mmol/l
0.77
58
203
282
1962
1.92
12.27
9.2
5.6
0.65
0.67
%
0.29
275
1839
380
2925
2.01
12.16
6.7
4.1
—
—
—
0
0
257
1738
1.91
12.16
2.7
2.3
70.86
75.84
nmol/l
1.71
234
1574
172
1016
2.02
12.11
2.3
2.0
2.87
3.12
mg/l
0.79
143
871
209
1322
1.95
12.07
3.2
2.3
—
—
—
0
0
288
2038
1.89
11.69
10.5
5.8
8.89
8.57
%
0.78
281
1926
34
90
3.96
11.64
11.9
2.9
—
—
—
0
0
207
1321
1.92
11.53
4.1
2.4
55.58
59.58
u/l
0.33
200
1227
286
2029
1.87
11.42
9.7
5.6
2.82
2.87
%
0.11
279
1908
292
2088
1.87
11.35
9.7
5.7
27.85
28.08
%
0.13
284
1972
161
953
1.98
11.13
1.7
1.6
18.91
20.67
nmol/l
0.86
142
809
157
922
1.99
11.09
4.4
3.6
—
—
—
0
0
236
1601
1.84
10.65
5.7
3.5
276.09
38.40
ng/l
0.46
166
1042
98
489
2.23
10.61
2.3
1.6
—
—
—
0
0
286
2064
1.82
10.48
9.8
5.5
56.78
57.09
%
0.18
278
1949
288
2087
1.81
10.37
4.9
3.5
0.00
0.00
estimate
-0.00
46
420
244
1708
1.78
9.66
4.5
3.3
6.03
5.86
ph
0.53
18
154
62
264
2.52
9.57
5.9
3.9
—
—
—
0
0
19
22
8.91
9.36
4.9
1.6
—
—
—
0
0
51
203
2.67
9.01
7.6
10.1
—
—
—
0
0
282
2091
1.73
8.87
6.6
4.8
0.00
0.00
estimate
0.50
43
391
71
335
2.29
8.73
2.3
2.3
7.03
6.79
ug/l
0.06
60
303
284
2116
1.72
8.73
5.0
3.6
0.00
0.01
estimate
0.50
41
376
159
1008
1.82
8.58
3.0
2.1
—
—
—
0
0
59
259
2.43
8.53
2.8
2.8
—
—
—
0
0
174
1139
1.78
8.41
3.6
3.1
974.19
1395.70
ng/l
1.41
153
956
113
648
1.94
8.31
2.2
2.3
13.51
13.45
umol/l
0.02
106
604
127
758
1.88
8.27
3.2
2.9
2.44
2.45
mmol/l
0.04
116
673
149
938
1.81
8.18
5.5
3.8
1.02
1.02
kg/l
0.73
33
122
19
29
6.75
7.95
1.9
1.4
—
—
—
0
0
94
518
1.99
7.72
1.6
1.6
—
—
—
0
0
15
17
9.04
7.58
3.5
2.2
258.90
76.67
umol/l
—
10
9
385
3184
1.73
7.50
5.0
3.9
13.73
11.12
mm/h
2.39
362
2943
263
1979
1.64
7.33
3.0
2.5
—
—
—
0
0
256
1917
1.64
7.25
13.3
8.8
0.00
0.00
e9/l
0.02
196
1563
40
158
2.65
7.19
9.9
2.2
—
—
—
0
0
26
81
3.32
7.06
12.1
2.4
—
—
—
0
0
359
2937
1.66
7.05
4.5
3.5
—
—
—
0
0
101
592
1.87
6.87
2.1
2.0
—
—
—
0
0
24
73
3.39
6.77
1.3
1.3
4.31
4.55
u/ml
0.06
13
33
39
161
2.53
6.43
1.5
1.5
423.03
282.56
mu/l
0.98
34
147
95
558
1.85
6.40
2.4
2.4
24.25
22.62
%
0.49
85
476
72
390
1.98
6.18
2.6
2.3
0.21
0.22
g/l
0.33
72
368
386
3265
1.64
6.17
5.0
3.9
14.59
14.68
pmol/l
0.26
360
2996
44
197
2.34
6.11
10.1
2.3
—
—
—
0
0
44
197
2.34
6.11
9.9
2.3
—
—
—
0
0
59
300
2.09
6.02
3.5
3.9
77.18
81.92
ng/l
0.25
52
268
41
180
2.38
5.95
10.5
2.4
—
—
—
0
0
79
448
1.89
5.92
2.9
2.9
1.67
1.78
%
0.41
66
405
35
144
2.53
5.83
1.8
2.9
—
—
—
0
0
61
318
2.04
5.82
1.6
1.5
—
—
—
0
0
43
196
2.30
5.74
10.6
2.1
—
—
—
0
0
130
863
1.67
5.68
1.8
1.3
2.62
2.41
g/l
0.42
78
538
43
197
2.29
5.67
9.9
2.3
—
—
—
0
0
33
134
2.56
5.65
9.0
3.3
—
—
—
0
0
97
598
1.76
5.54
2.4
2.3
2.35
2.37
g/l
0.09
92
549
485
4414
1.97
5.47
32.1
14.9
139.60
139.65
mmol/l
0.19
480
4305
116
1681
0.61
5.38
3.0
2.6
—
—
—
0
0
485
4431
1.93
5.15
32.0
15.0
3.97
3.97
mmol/l
0.02
480
4314
37
166
2.32
5.13
1.8
2.3
1.13
1.50
g/l
1.64
31
149
30
122
2.54
5.13
1.4
1.4
251.05
301.43
ug/g
0.65
19
75
8
6
13.51
5.09
1.8
1.8
22.32
13.38
umol/l
—
8
6
16
45
3.63
5.08
2.3
1.8
89.42
89.50
%
0.02
16
45
114
752
1.65
5.06
1.9
1.7
1016.33
1177.36
nmol/l
1.33
95
584
481
4388
1.88
5.06
28.6
13.2
19.89
22.40
mg/l
1.30
441
3454
21
71
3.04
5.04
2.6
2.5
15.70
15.85
%
—
8
35
443
3956
1.67
4.94
6.3
4.6
1.88
2.16
mu/l
0.43
420
3642
58
319
1.92
4.77
3.3
2.9
62.81
69.57
e9/l
0.81
39
251
13
26
5.10
4.65
1.1
2.5
12.46
11.43
%
0.30
13
26
241
1913
1.47
4.56
3.1
2.7
108.58
123.27
ug/l
0.58
225
1781
350
2989
1.49
4.54
4.9
3.0
63.26
44.64
u/l
2.05
335
2820
39
191
2.12
4.41
11.4
2.7
0.62
0.68
%
0.60
39
191
45
233
2.02
4.40
3.9
3.0
0.23
0.12
e6/l
0.83
45
224
28
119
2.43
4.40
5.0
5.4
1.68
1.32
mmol/l
0.31
21
104
21
78
2.76
4.30
1.3
1.2
—
—
—
0
0
25
103
2.50
4.20
1.5
1.2
—
—
—
0
0
24
97
2.54
4.19
1.8
1.2
—
—
—
0
0
68
410
1.75
4.18
2.6
1.9
351.70
376.77
nmol/l
0.44
63
379
36
176
2.12
4.10
4.6
4.4
25.24
25.02
mmol/l
0.16
31
168
41
211
2.02
4.09
4.3
4.0
—
—
—
0
0
49
270
1.90
4.02
2.0
3.5
4.40
4.60
pmol/l
0.80
40
235
144
1056
1.50
3.96
3.1
2.5
2849.47
5987.49
umol/l
0.55
129
939
34
167
2.11
3.84
3.0
1.7
—
—
—
0
0
18
66
2.79
3.79
16.4
1.9
63.22
62.33
%
0.04
18
66
19
72
2.70
3.77
1.1
1.1
—
—
—
0
0
21
84
2.56
3.76
1.0
1.0
—
—
—
0
0
87
577
1.61
3.74
1.5
1.3
1033.33
471.11
titre
0.66
12
135
13
34
3.89
3.71
15.8
19.3
1139.85
1573.47
nmol/l
0.85
13
34
8
12
6.75
3.68
2.8
1.5
—
—
—
0
0
24
104
2.37
3.65
4.9
3.2
7.41
7.42
ph
0.51
18
88
55
325
1.77
3.63
1.2
1.2
—
—
—
0
0
27
530
0.48
3.47
1.1
1.3
—
—
—
0
0
115
826
1.50
3.46
2.0
1.9
—
—
—
0
0
21
90
2.39
3.28
1.3
1.6
24054.90
17574.30
e6/l
—
10
67
13
43
3.07
3.27
1.8
1.4
—
—
—
0
0
9
19
4.80
3.25
3.8
2.5
666.22
695.63
u/ml
—
9
19
9
19
4.80
3.25
1.1
1.3
152.11
145.53
nmol/l
—
9
19
21
92
2.33
3.14
3.6
2.6
—
—
—
0
0
19
80
2.43
3.09
1.2
1.5
—
—
—
0
0
25
119
2.15
3.09
1.4
1.4
12.35
9.17
u/l
0.39
18
100
5
5
10.08
2.98
12.8
1.2
—
—
—
0
0
13
46
2.87
2.93
1.2
1.3
—
—
—
0
0
22
103
2.18
2.84
5.7
4.2
34.19
124.23
mg/l
0.87
22
86
22
103
2.18
2.84
5.7
4.2
33.36
28.96
mg/l
0.17
22
86
30
159
1.94
2.81
12.6
4.5
—
—
—
0
0
95
685
1.47
2.79
1.8
1.6
—
—
—
0
0
15
60
2.54
2.72
1.3
1.5
—
—
—
0
0
12
40
3.04
2.71
3.4
3.1
—
—
—
0
0
126
963
1.40
2.70
1.3
1.3
0.76
1.40
u/ml
1.39
22
256
12
44
2.77
2.56
1.3
13.6
5.61
6.57
mmol/l
—
7
35
10
31
3.27
2.53
3.8
3.3
—
—
—
0
0
34
196
1.78
2.49
3.8
4.2
—
—
—
0
0
112
851
1.40
2.47
1.5
1.7
90110324.60
14840924.45
pmol/l
0.39
91
721
8
21
3.85
2.47
1.0
1.4
—
—
—
0
0
6
12
5.04
2.40
1.0
1.2
—
—
—
0
0
444
4142
1.40
2.37
5.2
4.3
5.97
5.92
mmol/l
0.34
415
3814
7
17
4.16
2.36
2.6
4.0
45271.43
35894.41
ug/l
—
7
17
427
3964
1.37
2.30
6.0
5.4
39.70
39.71
mmol/mol
0.01
407
3717
201
1686
1.31
2.30
2.3
2.0
—
—
—
0
0
28
156
1.84
2.30
3.8
2.1
7697.12
3688.13
u/l
—
8
60
6
13
4.65
2.27
4.0
13.3
—
—
—
0
0
68
479
1.48
2.26
1.4
1.3
—
—
—
0
0
14
60
2.37
2.23
1.4
1.3
—
—
—
0
0
140
1123
1.33
2.19
5.6
3.8
0.00
0.01
estimate
0.80
41
388
152
1235
1.32
2.17
5.9
3.4
7.81
7.74
mmol/l
0.06
140
1044
18
88
2.08
2.13
5.8
3.1
2.77
2.66
mmol/l
0.04
13
59
32
512
0.60
2.10
1.5
1.4
—
—
—
0
0
5
10
5.03
2.07
1.2
1.4
—
—
—
0
0
6
15
4.03
2.04
1.3
1.5
—
—
—
0
0
71
515
1.44
2.04
1.7
1.4
—
—
—
0
0
11
44
2.53
2.02
1.5
1.7
—
—
—
0
0
10
38
2.66
2.01
1.0
1.2
—
68.00
—
0
5
73
537
1.42
1.95
2.9
2.6
122.17
121.75
ug/g
0.00
66
436
15
71
2.14
1.94
1.1
1.1
1.40
113.88
iu/ml
—
5
19
9
33
2.76
1.94
1.8
1.3
—
—
—
0
0
17
85
2.03
1.92
4.8
2.4
—
—
—
0
0
7
22
3.21
1.88
3.6
2.4
—
—
—
0
0
49
338
1.49
1.83
3.8
3.2
—
—
—
0
0
15
74
2.06
1.76
4.7
4.4
—
—
—
0
0
16
81
2.01
1.76
1.7
2.1
135.09
129.46
g/l
0.45
11
59
50
352
1.46
1.70
1.6
1.4
—
—
—
0
0
10
42
2.41
1.62
3.7
2.5
—
—
—
0
0
5
14
3.59
1.62
1.8
2.9
—
—
—
0
0
44
307
1.47
1.58
1.2
1.2
223.61
164.16
iu/ml
0.29
17
126
5
15
3.35
1.52
2.2
2.0
29.60
93.51
ug/l
—
5
15
18
305
0.58
1.51
1.2
1.4
—
—
—
0
0
9
38
2.39
1.46
1.3
1.2
—
—
—
0
0
15
80
1.90
1.46
1.5
1.2
371.22
239.18
u/ml
—
9
43
18
103
1.77
1.42
3.9
2.3
12.67
12.41
mg/l
0.07
18
95
9
40
2.27
1.40
1.6
1.1
—
—
—
0
0
25
158
1.61
1.40
1.1
1.0
—
—
—
0
0
11
53
2.10
1.39
1.4
1.1
—
—
—
0
0
11
53
2.10
1.39
1.1
1.3
—
—
nmol/l
—
0
0
22
135
1.66
1.38
1.3
1.1
—
—
—
0
0
6
23
2.63
1.37
1.0
1.0
—
—
—
0
0
6
23
2.63
1.37
2.0
1.9
9.50
9.17
mmol/l
—
6
23
481
4640
1.34
1.30
16.8
9.8
27.03
26.77
u/l
0.14
469
4492
8
34
2.37
1.29
2.8
2.2
38.59
39.04
%
—
8
34
8
34
2.37
1.29
1.1
1.0
—
—
—
0
0
5
18
2.79
1.28
1.4
1.3
—
—
—
0
0
22
138
1.62
1.28
1.5
1.3
—
—
—
0
0
38
271
1.43
1.25
1.1
1.2
—
—
—
0
0
24
155
1.57
1.25
1.5
1.7
—
—
—
0
0
24
155
1.57
1.25
5.5
4.3
0.25
0.30
g/l
0.17
13
62
6
25
2.42
1.24
1.2
3.1
54.50
89.80
nmol/l
—
6
25
140
1202
1.22
1.23
4.6
3.2
—
—
—
0
0
5
19
2.65
1.22
1.0
1.1
209.20
185.51
mmol/24h
—
5
19
33
231
1.46
1.20
1.4
1.4
26.13
24.97
iu/l
0.08
26
201
11
57
1.95
1.17
1.5
1.2
—
—
—
0
0
137
1183
1.21
1.14
4.1
3.9
6.89
9.93
mg/mmol
0.60
97
765
8
40
2.01
1.12
1.0
1.1
—
—
—
0
0
64
509
1.29
1.09
1.1
1.3
—
—
—
0
0
13
75
1.75
1.03
2.2
2.6
—
—
—
0
0
11
60
1.85
1.03
1.5
1.3
0.42
0.54
nmol/l
0.89
11
55
129
1120
1.20
1.01
3.7
3.3
930.29
410.39
mg/l
0.38
96
743
473
4581
1.26
1.01
21.8
12.3
—
—
—
0
0
7
35
2.01
1.00
3.1
3.1
—
—
—
0
0
9
52
1.74
0.92
1.9
3.4
3.79
77.91
u/ml
—
9
52
14
86
1.64
0.91
2.3
1.6
—
—
—
0
0
87
735
1.22
0.91
1.4
1.3
26.80
34.19
iu/ml
0.28
34
242
6
29
2.08
0.89
1.7
3.8
—
—
—
0
0
39
299
1.33
0.89
1.2
1.4
—
—
—
0
0
20
136
1.49
0.87
1.2
1.2
—
—
—
0
0
6
30
2.01
0.87
1.2
1.1
—
—
—
0
0
29
214
1.38
0.84
2.6
2.4
—
—
—
0
0
18
260
0.68
0.83
1.2
1.7
—
—
—
0
0
81
689
1.21
0.80
1.3
1.3
38.17
14.29
u/ml
0.28
24
282
6
33
1.83
0.79
1.3
1.2
—
—
—
0
0
6
33
1.83
0.79
1.2
1.1
—
—
—
0
0
22
158
1.41
0.75
2.5
3.4
661.63
1217.72
u/ml
0.25
16
135
69
584
1.21
0.73
1.4
1.2
—
—
—
0
0
5
25
2.01
0.73
1.0
1.0
—
—
—
0
0
9
56
1.62
0.72
1.9
1.9
—
—
—
0
0
32
247
1.31
0.72
1.3
1.2
—
—
—
0
0
47
382
1.25
0.72
4.4
4.3
—
—
—
0
0
20
143
1.41
0.71
1.6
1.9
33.45
36.58
nmol/l
0.29
20
136
9
59
1.53
0.68
1.8
3.1
—
—
—
0
0
5
27
1.86
0.68
2.8
3.1
17.44
19.09
mu/l
—
5
27
7
43
1.64
0.67
1.4
1.8
24.35
19.72
ug/l
—
7
43
5
29
1.73
0.64
1.2
1.1
—
7.08
—
0
9
50
417
1.22
0.62
2.5
4.3
10.20
37.70
ug/l
0.77
38
346
5
90
0.55
0.56
1.2
1.6
—
—
—
0
0
6
37
1.63
0.55
1.3
1.2
—
—
—
0
0
16
117
1.38
0.53
1.9
1.8
3.24
5.72
iu/l
—
5
38
6
41
1.47
0.50
1.5
1.3
—
—
—
0
0
7
107
0.65
0.49
1.4
1.3
—
—
—
0
0
10
68
1.48
0.47
1.5
1.3
—
—
—
0
0
23
183
1.27
0.45
1.0
1.1
—
—
—
0
0
48
414
1.17
0.45
1.6
1.8
—
—
—
0
0
7
50
1.41
0.45
1.3
2.5
—
—
—
0
0
129
1192
1.11
0.44
1.4
1.4
—
—
—
0
0
124
1148
1.10
0.41
4.3
3.8
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
0.99
—
0
10
0
19
0.00
0.39
0.0
1.1
—
32.31
—
0
14
5
36
1.39
0.38
1.8
1.5
61.80
74.75
umol/l
—
5
36
6
43
1.40
0.35
3.8
1.6
29.00
32.49
pg
—
6
43
6
45
1.34
0.34
2.2
2.6
2.72
124.93
nmol/l
—
6
45
22
182
1.22
0.33
1.2
1.2
—
—
—
0
0
6
46
1.31
0.33
3.0
2.6
—
—
—
0
0
6
46
1.31
0.33
1.7
1.6
—
—
—
0
0
6
47
1.28
0.32
1.5
1.4
34.87
32.60
g/l
—
6
40
7
52
1.35
0.31
2.6
1.7
—
—
—
0
0
116
1091
1.08
0.29
1.8
1.7
1.62
1.41
mmol/l
1.15
102
921
10
76
1.32
0.28
1.2
1.1
—
13.44
—
0
7
493
4880
1.12
0.27
39.6
19.4
39.74
40.51
%
1.99
464
4602
8
66
1.22
0.27
2.0
2.7
—
—
—
0
0
10
78
1.29
0.24
2.4
3.3
39.80
56.81
%
—
10
78
6
85
0.70
0.24
1.0
1.1
—
—
—
0
0
418
4119
1.07
0.23
4.4
3.8
1.43
1.29
mmol/l
2.84
396
3821
5
39
1.28
0.23
1.4
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
8
103
0.77
0.21
1.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
492
4881
1.09
0.19
39.0
19.3
254.08
250.80
e9/l
0.49
480
4778
7
59
1.19
0.18
1.1
1.3
—
30.14
—
0
5
492
4885
1.08
0.17
39.0
19.3
4.44
4.53
e12/l
3.95
477
4771
492
4886
1.08
0.16
39.1
19.4
6.97
6.71
e9/l
1.27
477
4768
492
4888
1.07
0.15
39.2
19.4
133.18
136.47
g/l
5.26
486
4827
14
159
0.88
0.13
34.4
9.6
—
—
—
0
0
10
117
0.85
0.13
3.7
5.3
—
—
—
0
0
38
355
1.08
0.13
4.6
4.2
1.11
1.02
%
0.07
18
136
31
333
0.93
0.12
5.3
4.3
0.00
0.12
%
3.11
11
114
5
45
1.11
0.10
1.4
1.3
—
—
—
0
0
5
48
1.04
0.09
1.2
1.1
—
—
—
0
0
21
227
0.92
0.09
1.0
1.1
—
—
—
0
0
7
66
1.06
0.08
1.0
1.2
—
—
—
0
0
8
76
1.05
0.07
2.3
3.1
3.09
4.38
e9/l
—
8
76
7
85
0.82
0.07
1.0
1.1
—
—
—
0
0
44
456
0.96
0.06
1.5
1.4
—
—
—
0
0
434
4359
0.98
0.05
5.5
4.6
2.71
2.80
mmol/l
1.06
416
4050
430
4282
1.02
0.05
5.0
4.2
4.55
4.68
mmol/l
1.55
413
4015
23
221
1.04
0.03
1.1
1.1
—
6.20
—
0
5
425
4261
0.99
0.02
5.0
4.2
1.37
1.45
mmol/l
3.88
407
3972
75
740
1.02
0.02
2.6
2.7
0.95
0.79
ug/l
0.26
57
449
22
228
0.96
0.02
3.0
2.6
80.41
44.44
u/ml
0.31
22
217
131
1300
1.01
0.02
4.2
4.4
2.40
2.51
ug/l
0.05
117
1170
16
157
1.02
0.00
1.1
1.3
—
2.38
—
0
12
46
464
0.99
0.00
1.7
1.7
—
—
—
0
0
31
313
0.99
0.00
5.4
4.4
0.08
0.12
%
0.10
12
95
35
353
0.99
0.00
6.2
3.4
—
—
—
0
0
32
321
1.00
0.00
4.3
4.1
0.50
0.57
%
0.08
14
111
30
301
1.00
0.00
6.9
2.2
3.79
6.39
e9/l
1.13
22
252
5
57
0.88
0.00
2.0
2.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
3.6
—
8190.33
—
0
9
0
5
0.00
-0.00
0.0
7.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
-0.00
2.0
2.8
105.60
105.62
mmol/l
—
5
58
6
66
0.91
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
-0.00
2.0
2.8
3.78
4.06
mmol/l
—
5
58
7
73
0.96
-0.00
1.4
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
6.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint G6_PARALOTHUNS and mortality.

Females

Parameter HR [95% CI] p-value
G6_PARALOTHUNS 2.863 [2.26, 3.63] < 0.001
Birth year 0.987 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 320 out of 1060 females with G6_PARALOTHUNS died.

Males

Parameter HR [95% CI] p-value
G6_PARALOTHUNS 2.83 [2.28, 3.52] < 0.001
Birth year 0.987 [0.98, 1.0] 0.01

During the follow-up period (1.1.1998 — 31.12.2019), 413 out of 1080 males with G6_PARALOTHUNS died.

Mortality risk

Mortality risk for people of age

years, who have G6_PARALOTHUNS.

N-year risk Females Males
1 0.199% 0.461%
5 1.319% 3.017%
10 3.301% 7.971%
15 6.249% 14.537%
20 10.48% 24.181%

Relationships between endpoints

Index endpoint: G6_PARALOTHUNS – Other and unspecified paralytic syndromes

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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