Postpartum haemorrhage due to retained placenta

O15_POSTPART_HAEMORRH_PLACENTA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only females

293218

2. Check conditions

None

293218

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O72.0
  • Hospital discharge: ICD-9 6660
  • Cause of death: ICD-10 O72.0
  • Cause of death: ICD-9 6660

2 out of 7 registries used, show all original rules.

5825

4. Check minimum number of events

None

5825

5. Include endpoints

None

5825

6. Filter based on genotype QC (FinnGen only)

5594

Control definitions (FinnGen only)

Control exclude
!(NUMBER_OF_OFFSPRING>0), !(O15_DELIVERY, O15_DELIVERY_PROXY)

Extra metadata

First used in FinnGen datafreeze
DF8

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 37145 37145 -
Only index persons 36716 36716 -
Unadjusted period prevalence (%)
Whole population 1.06 1.06 -
Only index persons 1.35 1.35 -
Median age at first event (years)
Whole population - 30.09 -
Only index persons - 30.08 -

-FinnGen-

Key figures

All Female Male
Number of individuals 5594 5594 -
Unadjusted period prevalence (%) 1.98 1.98 -
Median age at first event (years) 30.60 30.60 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
5825
Matched controls
58250
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
31.2
307.7
1390
579
8831
FHL
Uterine exploration and / or scraping or suction emptying (ad 24 hours)
22.4
307.7
261
122
O72.0
ICD-10 Finland
Third-stage haemorrhage
4503599627370496.0
307.7
3835
*
6660B
ICD-9 Finland
Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM CUM RETENT PLAC TOTALI]
+∞
307.7
454
*
6660C
ICD-9 Finland
Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM CUM RETENT PLAC PARTIALI]
+∞
307.7
488
*
6660A
ICD-9 Finland
Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM STADII III]
+∞
307.7
1118
*
8832
FHL
Manual placenta removal and associated scraping
28.3
307.7
362
136
MBA04
NOMESCO Finland
Curettage of uterus after delivery
12.7
307.7
335
279
8841
FHL
Uterine emptying and scraping (ad 6 weeks)
21.3
245.0
184
89
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
4.1
222.9
668
1778
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
3.6
158.7
571
1712
WW500
NOMESCO Finland
Blood transfusion
5.0
148.8
329
684
MBC30
NOMESCO Finland
Repair of partial rupture of perineum
3.5
125.7
469
1434
O80.8
ICD-10 Finland
Other single spontaneous delivery
2.4
113.8
949
4434
O73.0
ICD-10 Finland
Retained placenta without haemorrhage
5.2
109.3
231
461
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
3.6
106.9
371
1080
O70.1
ICD-10 Finland
Second degree perineal laceration during delivery
2.6
87.0
554
2271
MBC20
NOMESCO Finland
Repair of obstetric laceration of vulva
5.5
79.6
155
287
O73.1
ICD-10 Finland
Retained portions of placenta and membranes, without haemorrhage
4.6
68.5
167
375
MBB10
NOMESCO Finland
Packing of delivered uterus
14.5
62.2
56
39
MBC00
NOMESCO Finland
Repair of obstetric laceration of cervix uteri
10.1
60.2
68
68
ZXD05
NOMESCO Finland
Urgent procedure
1.6
53.8
2084
15299
O71.3
ICD-10 Finland
Obstetric laceration of cervix
8.9
53.1
66
75
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
2.3
38.2
286
1254
WX600
NOMESCO Finland
Single shot through catheter
2.4
36.0
244
1024
O70.0
ICD-10 Finland
First degree perineal laceration during delivery
2.7
29.4
163
621
6653B
ICD-9 Finland
Other obstetrical trauma, Laceration of cervix
9.3
29.1
35
38
MAX99
NOMESCO Finland
Assistance to normal delivery
1.4
29.0
1395
10430
6671A
ICD-9 Finland
Retained placenta or membranes, without haemorrhage, Retained portions of placenta or membranes, without haemorrhage
4.4
27.3
69
160
8502
FHL
Evacuation and abrasion
1.8
24.4
348
1938
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
0.6
24.3
395
6521
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
2.0
23.2
254
1295
W92
ICPC
Compl labour/ delivery livebirth
1.8
23.0
349
1981
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.7
22.7
124
470
Z39.2
ICD-10 Finland
Routine postpartum follow-up
1.3
22.3
2062
16996
MBC10
NOMESCO Finland
Repair of obstetric laceration of vagina
1.8
22.2
341
1943
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
0.7
21.9
784
10871
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
1.9
21.3
281
1527
SPAT1197
SPAT
Extensive health check-up of expecting family
1.3
19.3
1956
16245
2800A
ICD-9 Finland
Iron deficiency anaemias, Secondary to blood loss (chronic)
7.5
19.1
27
36
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
1.3
18.6
2028
16984
O61.8
ICD-10 Finland
Other failed induction of labour
3.2
18.5
72
226
SPAT1379
SPAT
Health check-up of pregnant person
1.3
17.6
1754
14495
8834
FHL
Kerviksrupure repair
13.1
17.4
30
23
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
1.3
17.0
2210
18871
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
1.3
16.8
1185
9322
O41.8
ICD-10 Finland
Other specified disorders of amniotic fluid and membranes
3.0
16.5
71
237
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
1.6
16.5
375
2375
W85
ICPC
Gestational diabetes
1.5
16.2
605
4269
O81.4
ICD-10 Finland
Vacuum extractor delivery
1.4
16.1
766
5650
W78
ICPC
Pregnancy
1.3
16.1
2286
19687
O48
ICD-10 Finland
Prolonged pregnancy
1.5
15.7
470
3172
SPAT1380
SPAT
Postpartum check-up
1.3
15.4
1482
12150
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
1.8
14.3
222
1270
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
1.9
14.2
167
876
B01AB05
ATC
enoxaparin; parenteral
1.3
14.1
1267
10275
Z39.1
ICD-10 Finland
Care and examination of lactating mother
1.6
14.0
309
1945
8839
FHL
Other measure in this category
17.6
13.8
21
12
6670A
ICD-9 Finland
Retained placenta or membranes, without haemorrhage, Retained placenta without haemorrhage
3.5
13.6
46
133
SPAT1246
SPAT
Screening of depression or other psychiatric problem
1.5
13.4
468
3260
O82.0
ICD-10 Finland
Delivery by elective caesarean section
0.6
13.3
262
4154
8801
FHL
Suction cup delivery
1.9
13.3
171
923
MAE00
NOMESCO Finland
Outlet vacuum delivery
1.4
13.2
640
4729
ZXE00
NOMESCO Finland
One hour or less
1.2
13.1
2115
18357
8833
FHL
Correction of II ^ 0 or III ^ 0 perineumrupth or vaginal rupture
3.5
12.9
43
123
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
2.0
12.7
135
684
6482A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Anaemia
4.2
12.7
33
79
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
0.7
12.7
394
5664
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
2.1
12.6
111
524
SPAT1373
SPAT
Combined screening in early pregnancy
1.7
12.6
255
1570
MBB96
NOMESCO Finland
Other manual procedure on delivered uterus
20.1
12.4
18
9
SPAT1375
SPAT
Structural ultrasound screening, weeks 18+0-21+6
1.9
12.4
163
888
LFE20
NOMESCO Finland
Suture of perineum
4.7
12.3
28
60
PC7NT
NOMESCO Finland
Endovascular occlusion of uteral arteries to stop puerperal bleeding
9.3
12.0
24
26
H01CC01
ATC
ganirelix; parenteral
1.6
11.8
270
1716
O85
ICD-10 Finland
Puerperal sepsis
2.0
11.7
118
587
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
1.7
11.2
209
1260
6611B
ICD-9 Finland
Abnormality of forces of labour, Secondary uterine inertia
2.2
11.1
95
444
O63.1
ICD-10 Finland
Prolonged second stage (of labour)
1.5
11.1
343
2329
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
1.4
11.1
441
3147
N81.1
ICD-10 Finland
Cystocele
1.6
11.1
271
1749
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
1.2
10.9
1966
17172
6748X
ICD-9 Finland
Other and unspecified complications of the puerperium, not elsewhere classified, Other
3.6
10.8
34
94
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
1.3
10.6
1067
8741
MBA10
NOMESCO Finland
Manual exploration of delivered uterus
11.2
10.5
19
17
W90
ICPC
Uncompl labour/delivery livebirth
1.3
10.3
714
5567
N81.2
ICD-10 Finland
Incomplete uterovaginal prolapse
1.6
10.3
222
1390
O44.1
ICD-10 Finland
Placenta praevia with haemorrhage
2.3
10.2
76
336
6400A
ICD-9 Finland
Haemorrhage in early pregnancy, Threatened abortion
2.2
10.1
84
389
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
1.5
10.0
326
2239
O99.80
ICD-10 Finland
The fear of childbirth
1.3
10.0
670
5202
G02AB01
ATC
methylergometrine; systemic
2.6
9.9
55
212
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.3
9.9
1133
9418
MBC33
NOMESCO Finland
Repair of complete rupture of perineum
2.1
9.8
86
407
Z32.1
ICD-10 Finland
Pregnancy confirmed
1.2
9.7
1314
11124
6641B
ICD-9 Finland
Trauma to perineum and vulva during delivery, Second-degree perineal laceration
4.2
9.6
25
60
MBW96
NOMESCO Finland
Other operation after delivery or abortion
3.5
9.5
31
88
O20.0
ICD-10 Finland
Threatened abortion
1.5
9.5
269
1797
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.2
9.4
2476
22312
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
1.2
9.4
1147
9598
G03GA05
ATC
follitropin alfa; parenteral
1.5
9.0
315
2194
MAC96
NOMESCO Finland
Other induction or advancement of labour
1.5
8.9
281
1918
OAA12, ,
SPAT
1.3
8.8
575
4449
O86.1
ICD-10 Finland
Other infection of genital tract following delivery
1.9
8.7
99
517
WX408
NOMESCO Finland
General anesthesy, balanced
1.2
8.6
1074
8996
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
1.7
8.6
168
1029
O44.0
ICD-10 Finland
Placenta praevia specified as without haemorrhage
1.9
8.6
98
512
6661A
ICD-9 Finland
Postpartum haemorrhage, Other immediate postpartum haemorrhage[HAEMORRHAGIA POST PARTUM ATONICA UTERI]
2.8
8.6
41
147
N39.3
ICD-10 Finland
Stress incontinence
1.4
8.3
390
2865
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
1.9
8.2
92
477
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
1.3
8.1
739
5967
6654B
ICD-9 Finland
Other obstetrical trauma, High vaginal laceration
3.2
8.1
31
98
6340A
ICD-9 Finland
Spontaneous abortion, Complicated by genital tract and pelvic infection
1.7
8.0
150
910
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
1.2
8.0
1256
10768
O02.1
ICD-10 Finland
Missed abortion
1.3
7.8
564
4426
Z3232
NOMESCO Finland
Midwife
1.2
7.7
980
8221
TPH07
NOMESCO Finland
Cathetrisation of artery
1.5
7.6
245
1684
N81.6
ICD-10 Finland
Rectocele
1.4
7.5
308
2213
TMA00
NOMESCO Finland
Episiotomy
1.4
7.5
366
2709
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
2.1
7.4
70
343
ZXD00
NOMESCO Finland
Emergency procedure
1.6
7.3
175
1127
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.2
7.3
938
7870
LCA10
NOMESCO Finland
Curettage of body of uterus
1.6
7.3
151
940
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
1.5
7.2
230
1578
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
1.4
7.2
306
2214
ULC02
NOMESCO Finland
Hysteroscopy
1.4
7.1
302
2182
6310A
ICD-9 Finland
Other abnormal product of conception[OVUM ABORTIVUM]
1.7
7.0
119
703
6700A
ICD-9 Finland
Major puerperal infection
2.2
7.0
55
251
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.2
7.0
2999
27859
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
0.5
6.9
61
1207
G03GA01
ATC
chorionic gonadotrophin; parenteral
1.4
6.9
357
2668
N85.6
ICD-10 Finland
Intrauterine synechiae
4.0
6.9
19
48
OAA10, ,
SPAT
1.3
6.9
526
4156
TLW12
NOMESCO Finland
Insertion of frozen embryo
1.6
6.8
156
996
WX892
NOMESCO Finland
Monitored bed care
1.5
6.8
183
1213
MBA05
NOMESCO Finland
Curettage of uterus after abortion
1.7
6.7
110
645
OAA11, ,
SPAT
1.2
6.7
782
6493
2851A
ICD-9 Finland
Other and unspecified anaemias, Acute posthaemorrhagic anaemia
12.2
6.6
11
9
SPAT1189
SPAT
Other ultrasound examination during pregnancy
1.3
6.4
420
3250
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
1.4
6.4
295
2164
O43.2
ICD-10 Finland
Morbidly adherent placenta
8.1
6.3
13
16
Z10.8
ICD-10 Finland
Routine general health check-up of other defined subpopulations
1.4
6.3
236
1673
6535B
ICD-9 Finland
Disproportion, Unusually large foetus causing disproportion[EPÄTAVALLISEN ISO SIKIÖ (YLI 4500 G), SYNN AIKANA]
2.5
6.3
37
149
W17
ICPC
Post-partum bleeding
2.9
6.2
28
98
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.3
6.1
405
3139
6320A
ICD-9 Finland
Missed abortion[ABORTUS INHIBITUS (""""MISSED ABORTION"""")]
1.8
6.0
83
464

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
433
1489
3.06
95.06
1.7
2.3
3.52
3.72
g/l
2.76
407
1400
738
4860
1.59
28.02
1.7
2.0
28.52
28.91
s
1.14
706
4680
949
6952
1.44
21.19
1.5
1.4
—
—
—
0
0
1496
12217
1.30
16.12
1.9
1.8
—
—
—
0
0
2031
17288
1.27
15.66
1.8
1.7
—
—
—
0
0
1294
10446
1.31
15.03
2.2
2.1
—
—
—
0
0
2285
19799
1.25
14.92
1.9
1.8
—
—
—
0
0
296
1836
1.64
14.18
1.7
1.8
20.78
20.57
s
0.33
253
1472
3040
27379
1.23
13.34
2.7
2.4
—
—
—
0
0
1940
16658
1.25
13.30
1.9
1.8
—
—
—
0
0
1113
8998
1.29
12.50
1.6
1.4
—
—
—
0
0
255
1637
1.58
10.67
1.8
1.8
81.17
96.63
%
14.88
246
1560
2380
21231
1.20
10.50
2.1
2.0
—
—
—
0
0
2400
21482
1.20
10.07
2.2
1.9
—
—
—
0
0
428
3099
1.41
9.92
2.4
3.1
—
—
—
0
0
56
236
2.39
8.46
1.2
1.2
—
—
—
0
0
1629
14416
1.18
7.15
5.3
5.3
1.06
1.05
inr
0.64
552
5029
200
1346
1.50
6.89
1.6
1.5
—
—
—
0
0
531
4216
1.29
6.68
2.9
3.1
32.77
32.59
%
0.15
426
3385
33
126
2.63
6.21
1.0
1.0
—
—
—
0
0
1151
10110
1.17
5.33
2.9
3.0
98.63
100.29
%
1.90
1114
9766
4452
45989
0.86
5.10
11.5
11.6
332.59
332.26
g/l
1.92
4414
45696
1073
12052
0.87
4.34
3.2
3.2
—
—
—
0
0
716
6202
1.18
3.90
1.2
1.2
—
—
—
0
0
126
887
1.43
3.63
2.9
3.3
21.87
22.39
mg/l
0.06
79
536
98
660
1.49
3.55
3.4
3.1
—
—
—
0
0
5464
53912
1.22
3.27
9.6
9.0
—
—
—
0
0
2688
25499
1.10
3.27
3.5
3.6
6.05
6.16
mmol/l
2.53
2266
22311
580
5031
1.17
3.13
3.0
3.2
—
—
—
0
0
1045
11521
0.89
3.10
3.2
3.4
1.02
1.01
kg/l
0.97
177
1882
348
2887
1.22
3.10
2.4
2.2
5.13
4.75
umol/l
0.48
228
2116
3690
35686
1.09
2.72
4.0
3.9
856.07
1855.27
e6/l
1.44
42
374
1642
15331
1.10
2.67
3.8
4.4
1.21
1.22
mmol/l
4.17
1508
14294
68
454
1.50
2.66
1.6
1.6
5.32
5.57
mmol/l
0.61
63
390
12
42
2.86
2.54
1.3
1.4
—
—
—
0
0
5152
50736
1.13
2.45
9.0
9.4
17.97
17.69
mg/l
0.26
4104
39448
179
2237
0.79
2.42
2.3
3.1
57.62
72.54
ng/l
4.95
161
2033
289
2419
1.20
2.41
1.2
1.2
11.17
11.65
u/l
0.27
257
2063
32
541
0.59
2.37
1.7
1.7
48.54
49.06
mu/l
0.01
27
502
2746
28597
0.92
2.33
2.6
2.5
—
—
—
0
0
10
247
0.40
2.29
2.0
1.5
116.40
126.22
nmol/l
—
10
247
205
2503
0.81
2.26
1.1
1.1
0.96
8.26
u/ml
—
5
35
23
120
1.92
2.25
1.0
1.2
—
—
—
0
0
2240
21331
1.08
2.23
1.9
1.9
—
—
—
0
0
84
1148
0.73
2.23
1.2
1.2
263.06
251.80
u/ml
0.11
58
807
240
1991
1.21
2.22
1.3
1.3
22.93
25.39
u/l
0.58
195
1648
524
5892
0.88
2.15
2.4
2.3
2.41
2.41
mmol/l
0.32
456
5122
283
2398
1.19
2.11
1.2
1.3
3.20
3.84
ug/l
1.53
262
2245
1873
19733
0.93
2.08
2.2
2.2
75.72
4469.28
nmol/l
0.50
1767
18658
1253
11681
1.09
2.06
1.8
1.7
1.38
0.82
mg/l
5.30
976
8708
240
2011
1.20
2.03
1.4
1.5
0.47
0.50
nmol/l
0.21
204
1599
988
10688
0.91
2.03
1.3
1.3
7.92
8.32
u/ml
0.09
439
4736
52
756
0.69
2.01
1.4
1.6
4686.64
7386.71
e6/l
1.09
36
566
5721
56903
1.30
1.95
14.6
14.1
131.20
132.99
g/l
26.78
5693
56550
81
1083
0.74
1.91
4.1
4.5
1.28
1.15
mmol/l
1.19
70
960
31
496
0.62
1.90
1.2
1.4
—
—
—
0
0
1688
15983
1.08
1.90
2.7
2.7
—
—
—
0
0
142
1136
1.26
1.89
3.0
2.6
—
—
—
0
0
290
3365
0.85
1.88
1.6
1.9
—
—
—
0
0
762
6977
1.11
1.84
2.5
2.3
8498.13
7466.36
u/l
0.40
439
3290
5705
56742
1.26
1.79
14.5
14.0
39.76
39.83
%
0.03
5516
54315
1837
17484
1.07
1.78
4.4
4.9
1.21
1.22
mmol/l
8.07
1554
14974
5712
56823
1.27
1.76
14.5
14.1
259.45
267.31
e9/l
20.37
5652
55979
5717
56879
1.28
1.76
14.5
14.1
7.03
6.74
e9/l
14.06
5650
55945
5717
56880
1.27
1.75
14.5
14.1
4.40
4.45
e12/l
21.84
5649
55988
5716
56869
1.27
1.75
14.4
14.0
30.02
30.01
pg
0.26
5688
56522
12
54
2.22
1.73
1.1
1.1
32.67
35.61
s
—
7
42
5716
56872
1.27
1.72
14.5
14.0
90.03
90.06
fl
0.18
5687
56525
1200
12778
0.92
1.71
2.9
2.9
2.35
2.35
mmol/l
0.08
1096
11770
617
5614
1.11
1.69
1.9
2.2
311.15
375.27
ng/l
0.35
473
4495
328
3737
0.87
1.68
3.3
4.6
1.03
1.04
mmol/l
0.56
314
3530
58
416
1.40
1.68
1.1
1.2
—
—
—
0
0
1499
15813
0.93
1.67
3.7
4.0
36.98
36.96
g/l
0.05
1397
14860
2232
21453
1.07
1.59
7.2
7.3
0.00
0.00
e9/l
0.23
1906
17869
309
3514
0.87
1.56
1.2
1.3
—
—
—
0
0
91
711
1.28
1.53
1.4
1.3
—
—
—
0
0
3027
29406
1.06
1.50
3.0
2.9
62.96
63.42
ug/l
0.08
2859
28072
111
894
1.25
1.46
1.3
1.5
—
—
—
0
0
1039
11051
0.93
1.44
1.3
1.3
21.45
26.06
iu/ml
0.69
331
3723
755
8134
0.92
1.44
3.5
3.7
13.13
11.45
mg/mmol
0.39
467
5222
12
59
2.04
1.43
1.2
1.2
—
—
—
0
0
629
5785
1.10
1.42
1.6
1.5
—
—
—
0
0
4753
48162
0.93
1.41
4.9
5.0
1.63
1.81
mu/l
1.84
4546
46153
40
280
1.43
1.37
2.7
2.7
39347.50
39675.11
ug/l
0.07
40
280
303
3413
0.88
1.36
2.1
2.0
—
—
—
0
0
616
5675
1.10
1.36
1.5
1.5
—
—
—
0
0
974
9151
1.08
1.34
2.4
2.4
—
—
—
0
0
617
5690
1.09
1.33
1.5
1.5
—
—
—
0
0
133
1593
0.83
1.33
5.7
6.2
23.13
24.24
mmol/l
4.29
126
1507
35
500
0.70
1.33
1.3
1.4
272.83
658.57
pmol/l
1.18
30
443
43
592
0.72
1.32
1.2
1.5
—
—
—
0
0
303
3403
0.88
1.31
2.0
1.9
—
—
—
0
0
548
5959
0.91
1.30
2.6
2.5
358.45
306.50
ng/l
0.11
293
2684
92
738
1.25
1.29
2.0
2.0
135.62
131.31
g/l
1.46
68
565
22
137
1.61
1.29
1.3
1.1
3.40
4.00
iu/ml
—
5
7
302
3387
0.89
1.28
2.1
2.0
—
—
—
0
0
952
8954
1.08
1.28
1.5
1.6
—
—
—
0
0
114
938
1.22
1.27
3.1
3.5
56.00
56.99
%
0.45
114
938
35
243
1.44
1.27
1.1
1.1
—
—
—
0
0
129
1541
0.83
1.27
4.1
4.6
—
—
—
0
0
15
84
1.79
1.27
1.0
1.0
—
—
—
0
0
689
6412
1.08
1.22
1.3
1.3
27.53
27.86
iu/l
0.10
624
5665
8
37
2.16
1.21
1.0
1.1
8.83
11.28
pmol/l
—
8
37
38
523
0.72
1.19
1.2
1.2
—
—
—
0
0
501
5439
0.91
1.17
1.5
1.6
—
—
—
0
0
14
79
1.77
1.16
1.4
2.2
—
—
—
0
0
3900
39684
0.95
1.16
3.6
3.8
36.78
37.06
mmol/mol
1.68
3717
37874
119
995
1.20
1.15
1.2
1.2
2.77
4.43
u/ml
1.97
48
401
5
111
0.45
1.12
1.2
1.1
—
297.14
—
0
7
22
330
0.67
1.11
1.1
1.2
—
68.00
—
0
5
116
973
1.20
1.10
1.0
1.1
119.00
119.71
%
0.12
106
889
120
1010
1.19
1.10
1.4
1.3
—
—
—
0
0
203
2306
0.88
1.09
1.1
1.2
—
—
—
0
0
5
21
2.38
1.09
1.2
1.9
—
—
—
0
0
95
1147
0.83
1.08
1.5
1.4
8445.49
1180.93
e6/l
0.57
79
951
95
1146
0.83
1.07
1.5
1.3
35.34
22.22
e6/l
0.39
76
899
282
3136
0.89
1.07
1.1
1.1
—
—
—
0
0
1317
13755
0.95
1.06
2.2
2.3
70.90
57.77
u/l
0.35
1230
12906
20
302
0.66
1.05
2.3
2.5
36.94
71.73
mg/l
0.50
14
210
3506
35727
0.95
1.05
3.4
3.6
8.70
9.08
mm/h
1.60
3309
33860
3281
33483
0.95
1.04
6.1
6.2
72.06
71.83
u/l
0.12
3103
31782
66
823
0.80
1.03
1.4
1.5
0.71
0.61
g/l
0.58
47
634
11
60
1.83
1.02
1.1
1.2
—
—
—
0
0
4258
43165
0.95
1.01
4.4
4.4
14.17
14.21
pmol/l
0.62
4019
41031
56
439
1.28
1.00
1.1
1.1
3.15
8.29
iu/ml
4.05
18
130
51
395
1.29
1.00
1.2
1.2
11.17
20.05
u/ml
—
6
43
101
847
1.20
0.99
1.9
2.3
—
—
—
0
0
2275
23389
0.96
0.97
4.6
5.2
0.04
0.04
e9/l
1.38
2058
20805
20
132
1.52
0.96
1.1
1.0
1.04
1.40
u/ml
0.13
13
92
51
649
0.78
0.96
5.1
5.9
106.50
105.74
mmol/l
0.64
46
578
51
649
0.78
0.96
5.1
5.9
11.35
10.97
mmol/l
0.48
46
578
0
31
0.00
0.96
0.0
1.0
—
0.12
—
0
13
938
9864
0.94
0.96
2.9
3.1
7.20
7.67
mmol/l
2.64
845
8812
0
32
0.00
0.95
0.0
1.3
—
0.20
—
0
12
800
8450
0.94
0.94
2.1
2.2
7.74
8.67
e6/l
0.86
697
7423
2162
21015
1.05
0.92
2.1
2.1
—
—
—
0
0
736
7789
0.94
0.92
2.9
3.2
323.15
538.23
mg/l
0.80
455
4935
43
553
0.78
0.90
2.4
2.5
79.53
95.03
ug/min
0.08
26
368
368
3390
1.09
0.88
1.1
1.1
120.42
236.53
titre
0.87
12
95
281
3084
0.91
0.88
2.1
2.0
—
—
—
0
0
2091
21490
0.96
0.86
4.9
4.8
9.61
9.31
umol/l
0.95
1965
20272
1119
11671
0.95
0.86
1.3
1.4
2.14
2.08
g/l
0.71
717
7663
78
649
1.20
0.86
1.4
1.3
—
—
—
0
0
11
180
0.61
0.86
3.1
2.0
—
—
—
0
0
505
4721
1.08
0.85
1.2
1.3
—
—
—
0
0
1525
15776
0.95
0.84
2.9
3.1
75.45
65.07
e6/l
0.29
961
9917
973
10180
0.95
0.84
2.9
3.3
7.39
7.40
ph
1.70
213
2042
2094
21501
0.96
0.82
2.8
2.9
5.99
5.97
ph
0.09
242
2460
3725
36693
1.04
0.81
3.8
3.9
—
—
—
0
0
1381
14306
0.95
0.81
1.3
1.3
1.57
1.58
u/ml
0.02
440
4389
620
5851
1.07
0.81
1.1
1.2
—
—
—
0
0
41
521
0.79
0.80
1.2
1.2
—
—
nmol/l
—
0
0
472
5042
0.93
0.80
1.2
1.2
—
—
—
0
0
277
2534
1.10
0.80
1.7
1.7
—
—
—
0
0
8
48
1.67
0.78
1.3
1.1
20.61
20.58
mmol/l
—
8
40
0
26
0.00
0.78
0.0
1.0
—
0.01
—
0
7
74
621
1.19
0.77
2.3
2.4
—
—
—
0
0
63
521
1.21
0.76
1.4
1.6
—
—
—
0
0
2281
23345
0.96
0.75
4.6
5.2
0.51
0.51
e9/l
0.00
2067
20824
283
3074
0.92
0.74
3.1
3.1
—
—
—
0
0
7
38
1.84
0.73
1.3
1.1
—
—
—
0
0
59
488
1.21
0.72
1.3
1.2
—
—
—
0
0
16
229
0.70
0.70
1.1
1.3
123.97
142.75
mmol/24h
0.76
16
229
1138
10975
1.05
0.69
2.0
2.0
2.67
2.60
mg/l
0.51
980
9549
100
1146
0.87
0.69
1.1
1.2
3.46
3.54
mmol/l
0.55
91
1085
115
1011
1.14
0.69
1.3
1.2
—
—
—
0
0
488
4601
1.07
0.69
1.8
2.1
23.52
24.62
%
1.04
409
3966
611
5802
1.06
0.68
2.2
2.3
5.11
4.86
e6/l
0.10
336
3027
24
319
0.75
0.68
2.6
2.8
0.93
1.43
g/24h
1.02
12
172
2381
24304
0.97
0.67
4.6
5.1
2.01
1.98
e9/l
0.44
2199
22209
115
1015
1.14
0.66
1.2
1.3
—
—
—
0
0
21
283
0.74
0.66
1.2
1.4
4004.45
23150.78
e6/l
1.20
11
200
7
44
1.59
0.65
1.4
1.6
—
—
—
0
0
1025
10630
0.96
0.65
1.6
1.6
1.29
1.33
mmol/l
0.53
880
9344
15
103
1.46
0.64
1.0
1.1
—
—
—
0
0
587
5583
1.06
0.63
1.5
1.5
—
—
—
0
0
24
181
1.33
0.63
2.7
2.8
—
—
—
0
0
977
10133
0.96
0.62
1.8
1.9
140.38
131.62
u/l
0.15
945
9648
238
2579
0.92
0.62
2.2
2.1
—
—
—
0
0
8
50
1.60
0.61
1.3
1.2
—
—
—
0
0
18
130
1.39
0.61
1.1
1.1
—
—
—
0
0
138
1533
0.90
0.61
1.2
1.2
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
0.09
—
0
13
110
976
1.13
0.60
1.8
2.4
24.35
24.64
mmol/l
0.80
104
910
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
483
5092
0.94
0.59
1.6
1.6
1187.02
1192.08
nmol/l
0.04
370
4167
242
2613
0.92
0.59
1.4
1.3
3.52
0.81
u/ml
0.74
16
227
0
22
0.00
0.59
0.0
1.0
—
0.22
—
0
14
178
1948
0.91
0.59
2.0
2.3
0.13
0.24
e6/l
2.00
165
1849
155
1405
1.11
0.59
2.2
2.2
—
—
—
0
0
139
1540
0.90
0.59
1.5
1.6
6.50
6.47
mmol/l
0.07
130
1408
59
501
1.18
0.58
1.0
1.1
—
—
—
0
0
35
282
1.24
0.58
1.1
1.1
0.22
4.83
nmol/l
—
10
43
254
2733
0.93
0.57
2.2
2.4
1.65
1.67
%
0.15
230
2469
34
420
0.81
0.57
3.3
3.8
5.99
6.80
mmol/l
0.90
27
328
67
577
1.16
0.56
1.8
2.0
—
—
—
0
0
6
36
1.67
0.56
1.0
1.1
1.85
1.44
umol/24h
—
6
36
130
1441
0.90
0.56
3.0
2.6
—
—
—
0
0
450
4267
1.06
0.56
1.3
1.3
130.41
163.24
u/ml
0.72
419
3968
4689
47236
0.96
0.56
3.4
3.5
2.93
2.95
mmol/l
0.80
4476
45260
46
548
0.84
0.55
1.2
1.3
—
—
—
0
0
46
548
0.84
0.55
1.2
1.3
6.73
6.55
g/l
0.17
29
385
940
9725
0.96
0.55
1.5
1.5
—
—
—
0
0
46
547
0.84
0.54
1.2
1.3
0.41
0.38
g/l
0.26
31
383
46
547
0.84
0.54
1.2
1.3
3.21
3.07
g/l
0.19
31
381
6
38
1.58
0.54
1.0
1.1
—
—
—
0
0
197
1817
1.09
0.54
1.4
1.4
51.65
81.93
pmol/l
2.59
192
1773
167
1821
0.91
0.53
2.6
2.4
72.82
71.56
e9/l
0.19
122
1314
9
63
1.43
0.52
1.0
1.1
—
—
—
0
0
412
3908
1.06
0.52
2.2
2.4
28.94
30.31
u/ml
0.17
398
3782
119
1074
1.11
0.51
1.8
2.5
—
—
—
0
0
744
7719
0.96
0.50
2.2
2.4
519.90
528.50
mosm/kgh2o
0.41
621
6568
2390
24301
0.97
0.50
4.6
5.2
0.18
0.18
e9/l
0.22
2185
22006
512
4893
1.05
0.50
1.3
1.4
—
—
—
0
0
30
368
0.81
0.49
1.2
1.4
9.79
9.36
umol/l
0.30
30
355
24
302
0.79
0.49
1.3
1.3
—
—
—
0
0
187
2020
0.92
0.49
4.3
6.4
6.30
6.56
mmol/l
0.32
180
1949
132
1202
1.10
0.49
2.3
2.1
0.97
1.27
g/l
5.68
113
1053
164
1509
1.09
0.49
6.5
6.7
—
—
—
0
0
139
1520
0.91
0.48
1.2
1.1
—
—
—
0
0
39
326
1.20
0.48
1.7
1.5
—
—
—
0
0
796
8235
0.96
0.48
1.4
1.4
648.39
569.14
titre
0.43
143
1655
11
76
1.45
0.48
1.0
1.0
0.05
0.05
u/ml
—
6
41
220
2357
0.93
0.47
3.3
2.8
—
—
—
0
0
7
47
1.49
0.47
2.1
2.4
—
—
—
0
0
43
506
0.85
0.47
1.7
1.5
—
—
—
0
0
93
1036
0.90
0.47
1.3
1.3
301.35
326.25
ug/g
0.53
46
525
1297
12650
1.03
0.47
2.2
2.2
15.03
21.79
ng/l
1.77
483
4672
298
2811
1.06
0.47
2.5
3.0
1.23
1.23
mmol/l
0.61
263
2471
350
3689
0.95
0.46
1.2
1.2
—
—
—
0
0
17
221
0.77
0.46
2.1
2.6
50.09
45.95
%
0.76
11
135
39
461
0.84
0.45
1.1
1.1
—
—
—
0
0
5
85
0.59
0.45
1.0
1.2
—
—
—
0
0
559
5377
1.04
0.43
1.6
1.7
—
—
—
0
0
22
274
0.80
0.43
3.8
2.3
59.93
55.00
%
0.36
15
243
14
104
1.35
0.43
1.2
2.0
—
—
—
0
0
52
452
1.15
0.42
1.7
2.5
1.34
1.38
e9/l
0.13
45
397
143
1319
1.09
0.42
2.4
2.8
0.23
0.31
g/l
0.77
55
548
152
1642
0.92
0.42
1.7
2.2
56.04
70.19
ng/l
0.60
136
1458
37
313
1.18
0.42
1.0
1.0
—
—
—
0
0
210
1968
1.07
0.42
7.4
7.2
—
—
—
0
0
19
149
1.28
0.41
1.0
1.4
—
—
—
0
0
31
258
1.20
0.41
2.1
2.8
0.13
0.34
e9/l
1.04
31
253
1585
16164
0.97
0.41
2.6
2.9
30.36
28.72
u/l
0.38
1505
15514
0
15
0.00
0.41
0.0
1.5
—
437.04
—
0
15
73
816
0.89
0.41
1.1
1.1
12.41
11923.92
iu/ml
0.64
27
225
34
286
1.19
0.41
2.2
1.8
2.00
2.41
u/field
—
9
150
0
16
0.00
0.41
0.0
1.4
—
0.36
—
0
11
108
1182
0.91
0.41
1.2
1.3
109.85
109.39
u/ml
0.03
34
303
77
857
0.90
0.40
3.3
3.6
1.54
1.36
mmol/l
0.77
77
847
158
1699
0.93
0.40
1.8
1.8
8.95
4.77
ug/l
0.39
141
1504
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
26
314
0.83
0.39
1.2
1.3
—
—
—
0
0
7
105
0.67
0.39
2.3
1.6
—
—
—
0
0
464
4459
1.04
0.39
3.7
3.4
4.63
4.56
pmol/l
0.46
422
4073
16
204
0.78
0.39
1.1
1.1
—
—
—
0
0
88
798
1.10
0.38
1.0
1.1
—
—
—
0
0
623
6026
1.04
0.38
1.2
1.2
145.41
153.66
iu/ml
0.20
232
2485
544
5248
1.04
0.38
1.7
2.0
2.59
2.51
g/l
2.44
494
4865
12
159
0.75
0.38
17.6
16.3
898.67
1353.62
nmol/l
1.41
12
149
47
410
1.15
0.38
1.6
1.8
30.99
25.33
mg/l
0.24
15
120
355
3713
0.95
0.38
2.0
2.0
4.05
4.39
e9/l
1.16
299
3330
471
4893
0.96
0.37
2.3
2.3
6.33
5.87
umol/l
0.25
382
4140
92
838
1.10
0.37
1.0
1.1
—
—
—
0
0
5
37
1.35
0.37
1.0
1.1
—
—
—
0
0
21
170
1.24
0.37
1.8
2.2
—
—
—
0
0
262
2759
0.95
0.37
1.4
1.4
—
—
—
0
0
163
1742
0.93
0.36
2.2
2.0
1.16
1.17
g/l
0.14
152
1665
279
2932
0.95
0.36
2.3
2.1
0.23
0.23
g/l
0.19
264
2775
29
244
1.19
0.36
2.5
2.3
—
—
—
0
0
49
431
1.14
0.36
1.1
1.1
1455.92
1488.58
miu/ml
0.09
49
431
4469
44956
0.97
0.36
3.2
3.2
5.50
5.52
mmol/l
1.10
4228
42702
4612
45862
1.03
0.36
11.0
11.0
14.25
14.34
%
0.29
4560
45203
66
734
0.90
0.36
2.3
2.0
151.22
240.68
ug/l
0.92
60
637
97
1057
0.92
0.35
3.5
4.4
1.57
1.81
%
1.90
92
976
37
319
1.16
0.35
1.1
1.1
7.54
11.77
u/ml
—
7
67
116
1072
1.08
0.35
2.3
2.3
—
—
—
0
0
5
80
0.62
0.35
2.4
2.9
0.94
0.89
nmol/l
—
5
52
11
145
0.76
0.34
1.5
1.6
7.81
8.33
ug/l
0.32
11
145
1083
11069
0.97
0.34
5.1
5.5
—
—
—
0
0
212
2007
1.06
0.33
2.7
2.6
—
—
—
0
0
40
457
0.87
0.33
1.2
1.2
—
—
—
0
0
10
133
0.75
0.33
1.3
1.5
—
—
—
0
0
120
1291
0.93
0.33
1.3
1.3
530.43
451.50
mg/l
0.57
114
1242
34
293
1.16
0.33
2.1
2.6
—
—
—
0
0
65
719
0.90
0.33
2.1
1.8
10.33
10.11
g/l
0.13
56
673
21
173
1.21
0.32
1.5
1.4
—
—
—
0
0
44
498
0.88
0.32
2.9
3.2
23.94
42.68
mg/l
1.32
36
399
96
1041
0.92
0.32
3.6
4.5
0.89
0.96
%
0.99
91
962
157
1670
0.94
0.32
2.1
2.2
—
—
—
0
0
610
5923
1.03
0.32
1.8
2.1
14.86
14.98
umol/l
0.15
562
5551
10
74
1.35
0.32
1.0
1.0
0.49
0.31
u/ml
—
5
36
4649
46721
0.98
0.32
3.2
3.3
1.54
1.56
mmol/l
1.35
4462
44987
19
230
0.83
0.31
1.0
1.1
—
—
—
0
0
1392
14161
0.98
0.31
1.6
1.7
103.38
100.06
pmol/l
1.79
756
7798
334
3475
0.96
0.31
1.2
1.2
—
—
—
0
0
7
96
0.73
0.30
1.4
1.5
—
—
—
0
0
308
3209
0.96
0.30
3.5
3.9
0.06
0.31
%
0.77
53
635
44
495
0.89
0.30
2.9
3.2
18.44
24.71
mg/l
1.97
36
397
126
1178
1.07
0.30
1.0
1.1
5.58
4.35
u/ml
0.28
45
465
52
466
1.12
0.30
1.2
1.2
—
—
—
0
0
45
505
0.89
0.30
1.0
1.0
0.24
0.38
u/ml
—
6
107
159
1685
0.94
0.30
2.2
2.0
0.22
0.23
g/l
0.25
148
1607
17
207
0.82
0.30
1.1
1.0
—
—
—
0
0
32
278
1.15
0.29
1.2
1.1
—
—
—
0
0
29
335
0.86
0.29
2.2
2.6
—
—
—
0
0
825
8063
1.03
0.29
3.0
3.3
—
—
—
0
0
19
228
0.83
0.29
1.4
1.8
—
—
—
0
0
637
6203
1.03
0.29
2.1
2.2
0.78
1.11
e6/l
2.08
357
3414
165
1560
1.06
0.29
2.0
2.4
7.41
7.42
ph
0.88
20
213
2649
26755
0.98
0.29
6.6
7.2
3.86
3.91
e9/l
0.54
2369
23705
30
260
1.15
0.28
1.1
1.1
12.19
9.32
u/ml
0.27
15
156
23
195
1.18
0.28
1.1
1.1
—
—
—
0
0
21
248
0.85
0.28
3.1
6.5
9.82
10.75
mg/l
0.42
16
232
26
301
0.86
0.27
1.5
1.2
45.50
72.14
%
—
6
29
250
2608
0.96
0.27
1.6
1.8
1.32
1.33
g/l
0.05
231
2459
32
364
0.88
0.27
1.3
1.3
1.59
1.59
g/l
0.04
32
364
479
4932
0.97
0.27
1.3
1.3
—
—
—
0
0
306
3176
0.96
0.27
3.2
3.7
0.73
0.61
%
0.30
64
757
54
593
0.91
0.26
1.2
1.4
—
—
—
0
0
9
72
1.25
0.25
1.0
1.2
—
—
—
0
0
1493
14722
1.02
0.25
2.2
2.2
—
—
—
0
0
60
550
1.09
0.25
1.1
1.1
5.25
1.08
u/ml
0.39
15
166
540
5263
1.03
0.25
1.6
1.7
—
—
—
0
0
17
202
0.84
0.24
1.2
1.4
164.71
82.97
nmol/24h
0.37
17
202
198
2069
0.96
0.24
2.1
3.1
1.92
1.79
mmol/l
0.22
166
1728
43
476
0.90
0.24
2.9
3.1
1.47
1.39
ratio
—
5
69
4674
46924
0.98
0.24
3.2
3.3
4.86
4.89
mmol/l
1.72
4489
45203
11
137
0.80
0.24
1.3
1.5
41.12
36.80
g/l
0.73
11
128
1187
12054
0.98
0.24
2.5
2.6
46.33
73.65
e6/l
0.75
876
8926
131
1241
1.06
0.23
1.0
1.1
4.93
4.71
u/ml
0.04
53
555
35
391
0.89
0.23
1.3
1.6
45.27
46.17
%
0.05
22
223
12
147
0.82
0.23
1.2
1.2
—
0.25
—
0
8
17
143
1.19
0.23
1.0
1.4
—
—
—
0
0
30
338
0.89
0.23
1.0
1.1
—
—
—
0
0
5
39
1.28
0.23
2.0
2.7
29.80
40.18
pmol/l
—
5
30
5199
52124
0.98
0.22
7.7
8.0
23.83
24.10
u/l
0.40
5041
50832
30
337
0.89
0.22
2.2
1.5
1.74
1.23
promille
1.04
22
251
121
1147
1.06
0.22
1.2
1.2
—
—
—
0
0
5
41
1.22
0.22
1.0
1.6
65.40
55.63
%
—
5
35
282
2728
1.04
0.21
6.9
6.4
14.75
13.94
kpa
1.30
270
2612
69
642
1.08
0.21
1.5
1.3
—
—
—
0
0
30
336
0.89
0.21
1.3
1.3
66.50
68.17
umol/l
0.13
30
336
282
2729
1.04
0.21
6.9
6.4
4.91
4.97
kpa
0.73
270
2615
19
163
1.17
0.21
1.2
1.5
10.44
5.85
%
—
9
26
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
11.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
451.00
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
19
220
0.86
0.21
2.1
1.7
—
—
—
0
0
31
277
1.12
0.21
1.1
1.4
—
—
—
0
0
211
2032
1.04
0.21
1.6
1.6
7.47
7.52
mmol/l
0.13
206
1949
100
1058
0.94
0.21
2.1
2.6
0.66
0.66
%
0.01
100
1053
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
45
491
0.92
0.20
2.1
2.8
—
—
—
0
0
199
1915
1.04
0.20
2.1
2.2
3.82
8.12
iu/l
0.60
80
837
332
3416
0.97
0.20
1.2
1.2
—
—
—
0
0
92
974
0.94
0.20
3.7
4.3
—
—
—
0
0
165
1583
1.04
0.20
2.0
2.5
5.02
5.07
kpa
0.55
157
1511
35
386
0.91
0.20
2.5
3.3
—
—
—
0
0
38
417
0.91
0.19
1.3
1.2
—
—
—
0
0
123
1172
1.05
0.19
1.1
1.1
3.61
2.96
u/ml
0.17
67
652
349
3397
1.03
0.19
2.2
2.4
10.55
10.48
g/l
0.13
309
3144
183
1762
1.04
0.19
1.1
1.2
—
—
—
0
0
6
52
1.15
0.19
2.2
1.8
—
—
—
0
0
34
308
1.10
0.19
1.1
1.4
—
—
—
0
0
146
1399
1.04
0.19
1.0
1.1
1.80
1.54
u/ml
0.13
61
650
37
337
1.10
0.19
1.7
2.5
0.19
0.21
e9/l
0.24
30
284
74
696
1.06
0.18
3.0
2.9
—
—
—
0
0
137
1430
0.96
0.18
2.0
1.9
—
—
—
0
0
39
357
1.09
0.18
1.1
1.2
—
—
—
0
0
507
5175
0.98
0.18
2.7
3.0
0.84
0.83
mmol/l
0.75
474
4932
25
223
1.12
0.18
1.6
1.9
11.02
9.71
mg/l
0.67
18
181
7
60
1.17
0.17
1.0
1.1
0.08
0.26
u/ml
—
7
54
83
785
1.06
0.17
1.4
1.3
28.07
48.82
u/ml
—
6
52
42
455
0.92
0.17
1.7
1.6
—
—
—
0
0
153
1473
1.04
0.17
1.0
1.1
6.01
5.38
u/ml
0.15
63
747
28
309
0.91
0.16
1.9
2.8
—
—
—
0
0
3589
35727
1.01
0.16
2.6
2.6
33.15
32.59
u/l
0.16
3445
34379
40
369
1.08
0.16
1.9
2.2
44.27
42.97
%
0.25
40
361
25
277
0.90
0.16
1.2
1.1
—
—
—
0
0
338
3459
0.98
0.16
3.4
3.9
0.89
0.89
%
0.00
79
870
71
672
1.06
0.15
4.2
4.0
178.15
89.20
u/ml
0.48
27
232
6
80
0.75
0.15
1.0
1.4
—
—
—
0
0
800
7891
1.02
0.15
1.5
1.5
16212766.71
46219156.66
pmol/l
1.45
697
6995
122
1172
1.04
0.15
1.1
1.1
—
—
—
0
0
46
493
0.93
0.15
1.1
1.1
—
—
—
0
0
232
2385
0.97
0.15
7.2
6.8
96.98
96.61
%
0.41
222
2278
20
178
1.12
0.15
2.7
3.1
—
—
—
0
0
12
102
1.18
0.15
1.2
1.0
—
—
—
0
0
38
410
0.93
0.15
1.8
2.8
67.81
62.61
%
0.89
38
410
17
192
0.89
0.14
1.2
1.2
—
—
—
0
0
474
4825
0.98
0.14
1.3
1.3
—
—
—
0
0
147
1421
1.04
0.14
9.1
8.1
1.26
1.44
%
1.38
147
1412
280
2736
1.02
0.14
3.4
3.5
11.85
34.29
ug/l
0.85
185
1935
24
263
0.91
0.13
1.9
2.1
—
—
—
0
0
27
294
0.92
0.13
2.2
2.6
—
—
—
0
0
280
2739
1.02
0.13
6.9
6.4
-0.34
0.77
mmol/l
5.34
199
2085
11
94
1.17
0.13
1.4
1.4
—
—
—
0
0
12
138
0.87
0.13
1.0
1.0
—
—
—
0
0
9
110
0.82
0.13
1.2
1.1
—
—
—
0
0
105
1011
1.04
0.13
1.0
1.1
0.24
0.31
u/ml
0.11
18
254
350
3435
1.02
0.12
2.5
2.6
—
—
—
0
0
115
1191
0.96
0.12
1.9
2.1
8.48
10.06
mg/l
1.87
109
1121
63
662
0.95
0.12
2.3
2.6
2.18
2.12
mmol/l
0.06
34
390
139
1434
0.97
0.12
1.4
1.3
40.03
38.13
u/ml
—
9
149
327
3332
0.98
0.12
3.4
3.9
0.20
0.15
%
0.32
69
746
10
116
0.86
0.12
1.4
1.6
—
—
—
0
0
42
446
0.94
0.11
2.1
2.5
1.97
1.50
%
0.22
36
409
150
1459
1.03
0.11
1.1
1.1
—
—
—
0
0
17
153
1.11
0.11
1.1
1.2
—
—
—
0
0
12
105
1.14
0.11
1.3
1.6
—
—
—
0
0
1073
10822
0.99
0.11
2.4
2.6
0.21
0.26
e6/l
0.62
788
7932
227
2222
1.02
0.11
1.7
1.7
—
—
—
0
0
410
4162
0.98
0.11
1.4
1.5
346.67
286.03
mu/l
0.41
360
3702
139
1352
1.03
0.10
1.3
1.3
104.67
154.54
titre
0.48
15
130
19
173
1.10
0.10
1.3
1.2
—
—
—
0
0
2252
22628
0.99
0.10
4.4
5.0
56.10
56.08
%
0.02
2153
21436
89
921
0.97
0.10
1.0
1.0
—
—
—
0
0
57
545
1.05
0.10
1.2
1.1
1.05
1.05
ratio
0.05
25
205
2176
21861
0.99
0.09
4.5
5.2
2.74
2.82
%
1.15
2069
20589
108
1112
0.97
0.09
1.4
1.5
6.17
6.80
mmol/l
3.36
108
1099
58
605
0.96
0.09
2.1
1.7
39.70
39.51
g/l
0.11
49
562
54
564
0.96
0.09
1.9
1.9
17.97
17.01
%
1.48
30
265
4751
47431
1.01
0.09
7.8
8.3
139.47
139.60
mmol/l
3.95
4642
46266
125
1283
0.97
0.09
1.1
1.1
—
—
—
0
0
29
309
0.94
0.09
2.0
2.8
803.38
828.17
e6/l
0.11
29
302
204
2080
0.98
0.09
1.1
1.1
13.13
5.14
u/ml
0.41
25
352
115
1119
1.03
0.09
1.3
1.4
31.14
32.47
nmol/l
0.22
99
1038
11
97
1.13
0.09
1.2
1.5
—
—
—
0
0
1086
10936
0.99
0.09
2.4
2.5
—
—
—
0
0
146
1427
1.02
0.08
9.1
8.1
0.72
0.72
%
0.03
146
1420
5
62
0.81
0.08
1.8
2.5
—
—
—
0
0
5
64
0.78
0.08
1.2
1.6
—
—
—
0
0
5
65
0.77
0.08
1.4
1.4
—
18.33
—
0
6
25
234
1.07
0.08
1.2
1.4
—
—
—
0
0
55
529
1.04
0.08
1.6
1.4
—
—
—
0
0
243
2468
0.98
0.08
1.1
1.1
—
—
—
0
0
157
1539
1.02
0.07
1.4
1.3
2.12
9.04
u/ml
1.24
18
162
4476
44832
0.99
0.07
2.9
3.0
1.16
1.17
mmol/l
0.27
4299
43063
39
372
1.05
0.07
6.9
6.3
—
—
—
0
0
385
3806
1.01
0.07
2.2
2.3
33.87
35.29
u/l
0.12
315
3280
36
343
1.05
0.07
1.7
2.5
494.10
531.85
e6/l
0.25
29
285
137
1342
1.02
0.07
8.6
8.0
—
—
—
0
0
314
3101
1.01
0.07
1.3
1.3
—
—
—
0
0
8
91
0.88
0.06
2.6
3.4
—
—
—
0
0
8
93
0.86
0.06
1.1
1.1
—
—
—
0
0
8
93
0.86
0.06
1.1
1.1
—
—
—
0
0
8
93
0.86
0.06
1.4
1.5
—
—
—
0
0
8
93
0.86
0.06
1.1
1.1
—
—
—
0
0
788
7828
1.01
0.06
2.4
2.4
115.52
97.18
ug/g
0.95
612
6157
126
1285
0.98
0.06
1.1
1.1
—
—
—
0
0
23
244
0.94
0.06
1.3
1.6
2.08
2.70
u/field
0.20
13
168
147
1444
1.02
0.06
1.4
1.3
—
—
—
0
0
2690
26971
1.00
0.06
3.1
3.2
0.00
0.00
estimate
0.19
674
5828
96
938
1.02
0.06
1.3
1.3
1.31
1.24
nmol/l
0.31
86
812
18
193
0.93
0.06
1.3
1.7
—
—
—
0
0
76
780
0.97
0.06
2.1
2.7
7.41
7.42
ph
1.76
71
723
29
276
1.05
0.06
1.9
2.2
32.97
32.12
pg
0.49
29
276
369
3725
0.99
0.06
1.3
1.3
228.63
237.44
miu/ml
0.19
195
1933
37
385
0.96
0.05
2.0
2.1
—
—
—
0
0
2198
22042
1.00
0.05
5.0
5.6
—
—
—
0
0
159
1566
1.02
0.05
1.4
1.3
7.47
7.45
u/ml
0.00
25
259
18
192
0.94
0.05
2.8
1.9
348.27
197.70
umol/l
0.43
11
96
54
556
0.97
0.05
1.1
1.0
1.73
1.01
u/ml
0.23
13
123
2289
22947
1.00
0.05
4.6
5.1
30.32
30.17
%
0.33
2185
21765
38
394
0.96
0.05
1.1
1.1
306.45
299.84
mg/l
0.16
31
369
32
307
1.04
0.05
1.4
1.6
35.98
40.57
%
0.25
22
172
85
868
0.98
0.05
2.9
3.3
95.00
255.12
u/ml
0.47
75
726
24
252
0.95
0.05
1.0
1.2
—
—
—
0
0
226
2284
0.99
0.04
7.4
7.1
114.74
122.08
g/l
6.19
220
2210
141
1390
1.01
0.04
1.0
1.1
0.54
1.28
u/ml
1.82
46
548
62
605
1.03
0.04
1.1
1.1
1.40
1.45
g/l
0.56
52
569
109
1072
1.02
0.04
1.2
1.1
7.29
9.65
au/ml
0.29
11
73
360
3627
0.99
0.04
1.3
1.3
43.06
38.66
au/ml
0.15
16
192
43
417
1.03
0.04
2.1
2.1
—
—
—
0
0
15
160
0.94
0.04
1.1
1.1
—
—
—
0
0
17
160
1.06
0.04
1.2
2.1
266.67
184.40
e6/l
—
9
91
2723
27183
1.00
0.04
3.1
3.2
0.01
0.00
estimate
0.46
653
5678
49
477
1.03
0.04
1.0
1.0
—
—
—
0
0
818
8213
1.00
0.04
1.3
1.3
—
—
—
0
0
104
1056
0.98
0.04
1.5
1.3
—
—
—
0
0
2089
20933
1.00
0.04
4.6
5.2
0.68
0.69
%
0.41
1973
19608
12
129
0.93
0.03
1.0
1.0
—
—
—
0
0
12
129
0.93
0.03
1.0
1.0
—
—
—
0
0
12
129
0.93
0.03
1.0
1.0
—
—
—
0
0
458
4557
1.01
0.03
1.9
2.0
377.58
374.05
nmol/l
0.16
432
4240
10
92
1.09
0.03
1.1
1.6
—
—
—
0
0
2194
21975
1.00
0.03
4.8
5.4
7.75
7.73
%
0.18
2084
20778
124
1253
0.99
0.02
1.2
1.3
—
—
—
0
0
1453
14557
1.00
0.02
3.3
3.4
0.00
0.00
estimate
2.76
656
5688
50
490
1.02
0.02
1.1
1.2
1.30
1.45
u/ml
0.08
26
253
189
1903
0.99
0.02
2.0
2.1
67.91
67.59
g/l
0.21
171
1775
1068
10701
1.00
0.02
2.0
2.0
1395.58
1657.10
umol/l
0.18
971
9795
167
1659
1.01
0.01
1.1
1.1
1.27
2.26
u/ml
1.34
68
801
213
2141
0.99
0.01
1.7
1.7
—
—
—
0
0
736
7370
1.00
0.01
1.4
1.4
21.73
21.08
nmol/l
0.70
650
6618
2699
27002
1.00
0.01
4.2
4.3
0.00
0.00
estimate
0.29
663
5739
164
1633
1.00
0.00
1.7
1.8
—
—
—
0
0
4758
47588
1.00
0.00
7.8
8.4
3.88
3.89
mmol/l
1.72
4627
46305
42
426
0.99
0.00
1.1
1.1
—
—
—
0
0
86
854
1.01
0.00
1.4
1.4
11.18
5.09
iu/ml
—
6
15
390
3906
1.00
0.00
2.3
2.3
23.03
22.95
au/ml
0.01
29
420
13
125
1.04
0.00
1.0
2.3
—
—
—
0
0
33
328
1.01
0.00
2.0
1.7
—
—
—
0
0
16
155
1.03
0.00
1.2
1.2
—
—
—
0
0
38
378
1.01
0.00
1.0
1.1
—
—
—
0
0
18
185
0.97
0.00
1.7
2.6
12.38
11.10
%
0.64
18
185
109
1088
1.00
0.00
1.8
3.3
24.41
24.07
mmol/l
0.57
109
1068
175
1748
1.00
0.00
1.4
1.3
57.40
30.51
u/ml
0.39
11
132
11
114
0.96
0.00
1.2
1.0
—
—
—
0
0
10
103
0.97
0.00
2.2
2.7
—
—
—
0
0
24
244
0.98
0.00
1.1
1.1
1.62
1.93
u/ml
0.09
14
127
54
537
1.01
0.00
1.1
1.1
194.05
203.00
mg/l
0.28
44
477
55
553
0.99
0.00
1.2
1.2
35.88
37.05
mg/l
0.09
44
463
17
169
1.01
0.00
1.1
1.4
—
—
—
0
0
121
1207
1.00
0.00
1.2
1.2
—
—
—
0
0
19
189
1.01
0.00
2.5
2.1
2109.74
1927.04
ml
0.54
19
177
29
291
1.00
0.00
2.7
2.3
—
—
—
0
0
5
54
0.93
0.00
1.0
1.1
1.88
1.08
u/ml
—
5
38
6
67
0.90
0.00
2.2
1.8
16.50
39.09
pmol/l
—
6
60
5
56
0.89
-0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1298.00
—
0
5
7
77
0.91
-0.00
1.6
2.1
1.89
2.69
ug/l
—
7
72
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
53.40
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
30
300
1.00
-0.00
2.1
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
104.23
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
4.50
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
7.0
—
282.83
—
0
6
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
7
73
0.96
-0.00
3.3
1.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
8.3
—
10.20
—
0
6
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
73.33
—
0
9
0
7
0.00
-0.00
0.0
5.1
—
1.30
—
0
7
0
6
0.00
-0.00
0.0
6.8
—
14.28
—
0
6
0
6
0.00
-0.00
0.0
1.7
—
994.65
—
0
6
7
69
1.01
-0.00
1.0
1.1
—
—
—
0
0
9
89
1.01
-0.00
1.1
1.6
63.78
40.94
%
—
9
77
8
82
0.98
-0.00
2.1
1.5
7.59
51.74
u/l
—
8
68
0
5
0.00
-0.00
0.0
1.6
—
160.20
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
-0.00
3.2
3.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint O15_POSTPART_HAEMORRH_PLACENTA and mortality.

Females

Parameter HR [95% CI] p-value
O15_POSTPART_HAEMORRH_PLACENTA 0.584 [0.46, 0.74] < 0.001
Birth year 0.994 [0.99, 1.0] 0.144

During the follow-up period (1.1.1998 — 31.12.2019), 93 out of 19150 females with O15_POSTPART_HAEMORRH_PLACENTA died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_POSTPART_HAEMORRH_PLACENTA.

N-year risk Females Males
1 0.043% No data
5 0.36% No data
10 0.906% No data
15 1.602% No data
20 2.71% No data

Relationships between endpoints

Index endpoint: O15_POSTPART_HAEMORRH_PLACENTA – Postpartum haemorrhage due to retained placenta

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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