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Postpartum hemorraghe, parous women as controls

O15_POSTPART_HEAMORRH_LB

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

only females

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O72
  • Hospital discharge: ICD-9 666
  • Hospital discharge: ICD-8 6531
  • Cause of death: ICD-10 O72
  • Cause of death: ICD-9 666
  • Cause of death: ICD-8 6531

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
!(NUMBER_OF_OFFSPRING>0), !(O15_DELIVERY, O15_DELIVERY_PROXY)

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Parent code in ICD-10
O60-O75
Name in latin
Haemorrhagia post partum

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population - - -
Only index persons - - -
Unadjusted period prevalence (%)
Whole population - - -
Only index persons - - -
Median age at first event (years)
Whole population - - -
Only index persons - - -

-FinnGen-

Key figures

All Female Male
Number of individuals 12235 12235 -
Unadjusted period prevalence (%) 4.17 4.17 -
Median age at first event (years) 30.20 30.20 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
10992
Matched controls
96298
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
6660A
ICD-9 Finland
Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM STADII III]
+∞
323.0
1020
*
6660C
ICD-9 Finland
Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM CUM RETENT PLAC PARTIALI]
+∞
323.0
448
*
6660B
ICD-9 Finland
Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM CUM RETENT PLAC TOTALI]
+∞
323.0
421
*
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
3577.3
323.0
3543
12
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
475.1
323.0
2155
49
65310
ICD-8 Finland
Occipital presentation
+∞
323.0
696
*
MBA04
NOMESCO Finland
Curettage of uterus after delivery
47.5
323.0
606
118
6661A
ICD-9 Finland
Postpartum haemorrhage, Other immediate postpartum haemorrhage[HAEMORRHAGIA POST PARTUM ATONICA UTERI]
+∞
323.0
424
*
O72.0
ICD-10 Finland
Third-stage haemorrhage
+∞
323.0
3134
*
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
18.7
323.0
1450
778
O80.8
ICD-10 Finland
Other single spontaneous delivery
3.0
259.6
1762
5782
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
4.0
256.9
1148
2720
8832
FHL
Manual placenta removal and associated scraping
12.4
181.4
347
252
8831
FHL
Uterine exploration and / or scraping or suction emptying (ad 24 hours)
15.4
163.6
285
166
WW500
NOMESCO Finland
Blood transfusion
5.0
155.1
541
988
6661X
ICD-9 Finland
Postpartum haemorrhage, Other immediate postpartum haemorrhage[HAEMORRHAGIA POST PARTUM ACUTA ALIA]
+∞
154.8
156
*
SPAT1197
SPAT
Extensive health check-up of expecting family
1.7
132.4
3911
23542
Z39.2
ICD-10 Finland
Routine postpartum follow-up
1.7
131.5
3903
23513
8841
FHL
Uterine emptying and scraping (ad 6 weeks)
14.4
123.3
220
136
W78
ICPC
Pregnancy
1.6
121.0
4212
26364
O70.1
ICD-10 Finland
Second degree perineal laceration during delivery
2.8
116.7
851
2837
ZXD05
NOMESCO Finland
Urgent procedure
1.6
113.2
4126
26004
MBC30
NOMESCO Finland
Repair of partial rupture of perineum
3.1
111.9
670
1960
SPAT1380
SPAT
Postpartum check-up
1.7
101.8
2933
17217
SPAT1379
SPAT
Health check-up of pregnant person
1.6
97.6
3303
20208
O73.1
ICD-10 Finland
Retained portions of placenta and membranes, without haemorrhage
5.5
95.6
304
498
6662A
ICD-9 Finland
Postpartum haemorrhage, Delayed and secondary postpartum haemorrhage
+∞
91.2
92
*
MAX99
NOMESCO Finland
Assistance to normal delivery
1.7
90.7
2630
15374
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
1.5
84.6
3840
25021
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
1.6
82.0
2386
13894
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
1.5
76.0
4015
26866
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.6
68.2
2278
13649
O73.0
ICD-10 Finland
Retained placenta without haemorrhage
3.7
62.5
293
709
MBC00
NOMESCO Finland
Repair of obstetric laceration of cervix uteri
12.9
59.9
111
76
W85
ICPC
Gestational diabetes
1.8
58.5
1080
5431
O71.3
ICD-10 Finland
Obstetric laceration of cervix
12.7
58.0
108
75
W92
ICPC
Compl labour/ delivery livebirth
2.2
56.9
623
2550
MBC20
NOMESCO Finland
Repair of obstetric laceration of vulva
5.0
55.7
189
335
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.4
55.2
5760
42835
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
1.4
50.9
3923
27584
Z32.1
ICD-10 Finland
Pregnancy confirmed
1.5
50.7
2466
15912
G02AB01
ATC
methylergometrine; systemic
5.1
50.6
168
291
SPAT1375
SPAT
Structural ultrasound screening, weeks 18+0-21+6
2.7
50.0
370
1236
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
2.3
48.9
494
1946
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
2.2
47.7
528
2171
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
1.4
46.4
3233
22244
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
2.2
45.5
517
2152
SPAT1373
SPAT
Combined screening in early pregnancy
2.1
43.3
513
2172
O99.80
ICD-10 Finland
The fear of childbirth
1.6
43.0
1252
7161
W90
ICPC
Uncompl labour/delivery livebirth
1.6
42.8
1213
6888
MBB10
NOMESCO Finland
Packing of delivered uterus
19.0
42.3
67
31
MBC10
NOMESCO Finland
Repair of obstetric laceration of vagina
2.1
41.9
482
2016
WX600
NOMESCO Finland
Single shot through catheter
2.3
41.3
421
1666
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
1.4
40.4
2099
13627
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
1.4
40.4
2145
13987
Z34
ICD-10 Finland
Supervision of normal pregnancy
1.6
39.1
1153
6605
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
0.6
39.0
982
12693
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
1.4
38.5
2041
13285
SPAT1246
SPAT
Screening of depression or other psychiatric problem
1.7
38.5
902
4855
SPAT1200
SPAT
Guidance for breast-feeding and breast care
1.8
36.9
711
3605
Z39.1
ICD-10 Finland
Care and examination of lactating mother
1.9
36.0
526
2424
SPAT1195
SPAT
Antenatal classes
1.7
35.1
783
4150
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
34.1
4584
34370
ZXE00
NOMESCO Finland
One hour or less
1.3
32.4
4215
31391
O48
ICD-10 Finland
Prolonged pregnancy
1.7
32.2
795
4336
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
1.6
31.5
823
4557
O86.1
ICD-10 Finland
Other infection of genital tract following delivery
2.7
30.2
212
688
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
1.7
30.1
657
3457
O81.4
ICD-10 Finland
Vacuum extractor delivery
1.4
29.9
1366
8595
O72.3
ICD-10 Finland
Postpartum coagulation defects
+∞
29.7
30
*
SPAT1189
SPAT
Other ultrasound examination during pregnancy
1.6
29.4
790
4406
O85
ICD-10 Finland
Puerperal sepsis
2.5
29.1
240
853
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.4
28.8
2058
14014
Z10.8
ICD-10 Finland
Routine general health check-up of other defined subpopulations
1.9
28.7
449
2119
W29
ICPC
Pregnancy symptom/complaint other
1.7
28.7
636
3362
TMA00
NOMESCO Finland
Episiotomy
1.6
27.2
762
4296
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
1.5
26.9
1049
6385
MAE00
NOMESCO Finland
Outlet vacuum delivery
1.5
26.6
1164
7253
SPAT1196
SPAT
Monitoring of normal pregnancy
1.4
26.3
1654
11014
MBW96
NOMESCO Finland
Other operation after delivery or abortion
6.0
26.1
74
108
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
1.5
26.0
1144
7133
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
1.9
25.6
378
1751
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
1.7
24.9
560
2973
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
1.8
24.1
410
1994
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
1.3
23.4
2257
15994
O47.9
ICD-10 Finland
False labour, unspecified
1.8
23.3
394
1914
H01CC01
ATC
ganirelix; parenteral
1.8
23.2
453
2307
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
1.3
22.9
2528
18229
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
1.7
22.8
463
2386
WX307
NOMESCO Finland
Obstetric epidural analgesia
1.3
22.4
1972
13789
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
2.2
22.4
245
1007
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
2.2
22.1
231
929
O70.0
ICD-10 Finland
First degree perineal laceration during delivery
2.3
22.1
215
836
MBA05
NOMESCO Finland
Curettage of uterus after abortion
2.2
21.9
219
864
MBC33
NOMESCO Finland
Repair of complete rupture of perineum
2.6
21.5
166
573
PC7NT
NOMESCO Finland
Endovascular occlusion of uteral arteries to stop puerperal bleeding
13.4
21.4
38
25
Z37.0
ICD-10 Finland
Single live birth
1.3
21.2
2242
16050
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.3
20.5
1767
12300
MA3AE
NOMESCO Finland
Combined first trimester screening
1.4
20.5
1083
6979
ULC02
NOMESCO Finland
Hysteroscopy
1.6
20.4
625
3599
8834
FHL
Kerviksrupure repair
10.0
20.2
41
36
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
1.7
19.5
410
2136
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
1.4
19.5
1153
7574
N85.6
ICD-10 Finland
Intrauterine synechiae
7.8
19.2
45
51
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
2.4
18.9
163
599
Z3232
NOMESCO Finland
Midwife
1.3
18.7
1939
13823
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
1.5
18.5
587
3405
O44.0
ICD-10 Finland
Placenta praevia specified as without haemorrhage
2.2
18.5
187
743
R3110
NOMESCO Finland
Psychosocial training
1.8
18.3
323
1594
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
1.9
18.1
261
1199
8811
FHL
Cesarean section
0.6
17.9
402
5358
MBB96
NOMESCO Finland
Other manual procedure on delivered uterus
48.3
17.8
22
*
6500B
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
0.8
17.2
2049
21351
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
1.4
17.1
875
5602
O61.8
ICD-10 Finland
Other failed induction of labour
3.4
16.9
82
210
O71.4
ICD-10 Finland
Obstetric high vaginal laceration
2.3
16.5
149
561
O63.1
ICD-10 Finland
Prolonged second stage (of labour)
1.5
16.4
602
3611
G03GA05
ATC
follitropin alfa; parenteral
1.5
16.4
508
2934
6653B
ICD-9 Finland
Other obstetrical trauma, Laceration of cervix
6.5
16.0
42
57
WX306
NOMESCO Finland
Lumbar epidural anesthesy
1.3
15.9
1257
8622
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.2
15.5
5968
48317
O02.1
ICD-10 Finland
Missed abortion
1.3
15.5
1031
6894
N81.6
ICD-10 Finland
Rectocele
1.5
15.3
557
3336
TLW12
NOMESCO Finland
Insertion of frozen embryo
1.8
15.1
274
1369
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
1.6
14.8
358
1943
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.3
14.8
1612
11532
B01AB05
ATC
enoxaparin; parenteral
1.2
14.8
2094
15440
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
1.7
14.6
294
1517
W17
ICPC
Post-partum bleeding
4.3
14.3
53
108
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.2
14.3
1837
13390
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.0
14.2
173
749
6671A
ICD-9 Finland
Retained placenta or membranes, without haemorrhage, Retained portions of placenta or membranes, without haemorrhage
2.9
14.1
86
259
G03GA01
ATC
chorionic gonadotrophin; parenteral
1.4
13.9
688
4376
MAC96
NOMESCO Finland
Other induction or advancement of labour
1.5
13.7
523
3163
O20.0
ICD-10 Finland
Threatened abortion
1.5
13.6
496
2974
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.3
13.6
1377
9755
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
1.6
13.3
365
2048
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
1.6
13.3
387
2205
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
1.5
13.2
488
2936
SPAT1190
SPAT
Insertion or removal of intrauterine contraceptive device
1.3
13.1
1182
8246
O90.8
ICD-10 Finland
Other complications of the puerperium, not elsewhere classified
3.6
13.1
59
144
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
1.7
13.0
301
1614
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
1.4
13.0
683
4393
W12
ICPC
Contraception intrauterine
1.2
12.8
1796
13199
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
1.5
12.6
383
2208
8839
FHL
Other measure in this category
9.5
12.3
25
23
W84
ICPC
Pregnancy high risk
1.4
12.2
757
4999
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
12.2
4061
32253
N81.1
ICD-10 Finland
Cystocele
1.5
12.2
461
2785
6482A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Anaemia
3.9
11.9
48
107
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
2.1
11.8
130
543
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
1.6
11.7
269
1446
WX408
NOMESCO Finland
General anesthesy, balanced
1.2
11.6
2030
15245
MCA30
NOMESCO Finland
Supravaginal caesarean hysterectomy
17.5
11.5
18
9
ZXD00
NOMESCO Finland
Emergency procedure
1.5
11.5
349
2013
O44.1
ICD-10 Finland
Placenta praevia with haemorrhage
2.1
11.3
126
528
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
0.6
11.2
136
2079
SPAT1315
SPAT
Periodic health check-up of children and adolescents
1.4
11.1
567
3629
LCG02
NOMESCO Finland
Hysteroscopic freeing of adhesions
8.8
10.9
23
23
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
0.6
10.9
180
2555
SPAT1357
SPAT
Monitoring of problem during pregnancy
1.4
10.8
558
3579
103
Kela drug reimbursment
Diabetes, insulin-treated
0.8
10.8
646
7322
W05
ICPC
Pregnancy vomiting/nausea
1.8
10.7
195
980
O72
ICD-10 Finland
Postpartum haemorrhage
6.9
10.6
26
33
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
1.2
10.5
2265
17318
N81.2
ICD-10 Finland
Incomplete uterovaginal prolapse
1.5
10.5
375
2242
C10AA01
ATC
simvastatin; oral
0.8
10.3
778
8567
W18
ICPC
Post-partum symptom/complaint other
2.0
10.2
123
532
2800A
ICD-9 Finland
Iron deficiency anaemias, Secondary to blood loss (chronic)
5.0
10.2
32
56
SPAT1312
SPAT
General health counselling
1.2
10.2
2999
23512
215
Kela drug reimbursment
Diabetes, non-insulin-treated
0.8
10.2
646
7274
LCA10
NOMESCO Finland
Curettage of body of uterus
1.6
10.1
274
1540
SPAT1308
SPAT
Sexual health counselling
1.2
10.0
2137
16316
65400
ICD-8 Finland
Occipital presentation
0.3
10.0
16
530
8502
FHL
Evacuation and abrasion
1.4
9.9
518
3330
C09CA01
ATC
losartan; oral
0.8
9.8
670
7475
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
1.4
9.8
479
3044
O70.22
ICD-10 Finland
III degree perineal tear involving one half or more of external anal sphincter thickness torn during childbirth
3.2
9.8
50
137
O60
ICD-10 Finland
Preterm labour and delivery
1.4
9.7
497
3184
O47.1
ICD-10 Finland
False labour at or after 37 completed weeks of gestation
1.3
9.7
712
4828
O41.8
ICD-10 Finland
Other specified disorders of amniotic fluid and membranes
2.4
9.7
82
305
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
1.3
9.7
728
4956
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
1.8
9.6
147
701
MCW00
NOMESCO Finland
Obstetric hysterectomy
14.0
9.5
16
10
PC1CC
NOMESCO Finland
Very extensive angiography of aorta and abdominal arteries
8.0
9.5
21
23
LCB25
NOMESCO Finland
Hysteroscopic excision of lesion
1.4
9.5
459
2913
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
1.5
9.4
363
2208
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.2
9.3
1922
14623
O70.2
ICD-10 Finland
Third degree perineal laceration during delivery
1.9
9.3
131
607
A10AE04
ATC
insulin glargine; parenteral
0.6
9.3
200
2683
66180
ICD-8 Finland
Occipital presentation
0.3
9.3
26
656
O47
ICD-10 Finland
False labour
1.7
9.2
182
939
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
0.6
9.1
101
1579
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
1.2
9.1
1352
9981
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
1.4
9.1
379
2344
O75.6
ICD-10 Finland
Delayed delivery after spontaneous or unspecified rupture of membranes
1.5
8.9
310
1848
6531B
ICD-9 Finland
Disproportion, Generally contracted pelvis[PELVIS ANGUSTA,SYNNYTYKSEN AIKANA]
0.2
8.9
6
332
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
1.3
8.9
628
4237
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.2
8.8
2886
22757
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
1.3
8.8
621
4189
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
1.5
8.7
278
1627
H01CA02
ATC
nafarelin; nasal
1.4
8.6
398
2505
A10AA02
ATC
NA
0.5
8.6
71
1206
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
1.7
8.6
166
855
O20.8
ICD-10 Finland
Other haemorrhage in early pregnancy
1.9
8.5
118
545
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
1.3
8.4
531
3523
SPAT1389
SPAT
Visit based on need for special support
1.5
8.4
279
1647
N97.9
ICD-10 Finland
Female infertility, unspecified
1.3
8.4
898
6393
O62.3
ICD-10 Finland
Precipitate labour
3.0
8.4
46
134
MBC96
NOMESCO Finland
Other repair of obstetric laceration
6.0
8.3
22
32
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
1.4
8.3
363
2267
G03GA06
ATC
follitropin beta; parenteral
1.4
8.3
389
2458
A10AA01
ATC
NA
0.5
8.2
71
1191
O75.0
ICD-10 Finland
Maternal distress during labour and delivery
1.6
8.2
212
1182
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
1.4
8.2
385
2435
O67.9
ICD-10 Finland
Intrapartum haemorrhage, unspecified
2.4
8.2
69
257
WX322
NOMESCO Finland
Combined spinal-epidural analgesia in obstetrics
1.4
8.2
357
2227
C10AA05
ATC
atorvastatin; oral
0.8
8.1
873
9257
K05.31
ICD-10 Finland
Periodontitis pronounced
0.7
8.1
244
3069
TLW00
NOMESCO Finland
Insemination
1.5
8.1
301
1819
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
0.5
8.1
55
993
W11
ICPC
Contraception oral
1.2
8.0
1250
9269
WX400
NOMESCO Finland
Inhalation anesthesy
1.4
8.0
405
2598
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
1.5
7.9
267
1580
MBA10
NOMESCO Finland
Manual exploration of delivered uterus
5.9
7.9
21
31
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
0.6
7.9
93
1430
SPAT1324
SPAT
Screening procedure
0.9
7.8
2538
24599
SPAT1192
SPAT
Gynaecological examination
1.2
7.8
1716
13113
WYA40
NOMESCO Finland
Assessment of oral health and treatment needs for family expecting first child
1.4
7.7
345
2163
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.2
7.7
977
7094
M65.3
ICD-10 Finland
Trigger finger
0.6
7.6
130
1826
O30.00
ICD-10 Finland
Twin pregnancy with separate amniotic and chorionic sacs
2.0
7.6
91
399
O75.7
ICD-10 Finland
Vaginal delivery following previous caesarean section
2.3
7.6
66
251
OAA11
SPAT
NA
1.3
7.6
513
3445
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
1.5
7.5
275
1657
O70.21
ICD-10 Finland
III degree perineal tear involving less than one half of external anal sphincter thickness torn during childbirth
2.5
7.4
56
199
WX320
NOMESCO Finland
Spinalanesthesy
1.2
7.4
1793
13805
T89
ICPC
Diabetes insulin dependent
0.6
7.4
115
1648
O34.3
ICD-10 Finland
Maternal care for cervical incompetence
1.9
7.4
101
465
TLW10
NOMESCO Finland
Transfer of fresh embryo
1.5
7.3
248
1473
O91.2
ICD-10 Finland
Nonpurulent mastitis associated with childbirth
1.5
7.3
221
1282
I10
ICD-10 Finland
Essential (primary) hypertension
0.9
7.3
1965
19301
O26.7
ICD-10 Finland
Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
1.6
7.2
200
1137
N76.0
ICD-10 Finland
Acute vaginitis
1.2
7.2
864
6236
O82.0
ICD-10 Finland
Delivery by elective caesarean section
0.8
7.2
594
6474
6542B
ICD-9 Finland
Abnormality of organs and soft tissues of pelvis, Previous Caesarean delivery[CICATRIX UTERI POSTOPERATIVA, SYNNYTYKSEN AIKANA]
0.4
7.1
31
652
C03CA01
ATC
furosemide; systemic
0.8
7.1
469
5249
SPAT1128
SPAT
Instruction of pelvic floor / sphincter exercises
1.7
7.1
148
781
J01DB01
ATC
cefalexin; oral
1.1
7.1
8485
72100
O21
ICD-10 Finland
Excessive vomiting in pregnancy
1.6
7.0
151
807
MAW96
NOMESCO Finland
Other operation in pregnancy or at delivery
1.7
7.0
128
651
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
1.2
6.9
865
6268
O32.2
ICD-10 Finland
Maternal care for transverse and oblique lie
1.7
6.9
124
627
LCB98
NOMESCO Finland
Other transluminal endoscopic excision of lesion of uterus
1.8
6.9
103
491
R21
ICPC
Throat symptom/complaint
1.1
6.9
2412
19064
WX892
NOMESCO Finland
Monitored bed care
1.4
6.8
315
1992
SPAT1310
SPAT
Counselling related to known health issue
1.1
6.8
2641
21011
MWE00
NOMESCO Finland
Reoperation for deep haemorrhage in obstetric surgery
2.8
6.8
40
124
T81.2
ICD-10 Finland
Accidental puncture and laceration during a procedure, not elsewhere classified
1.8
6.7
102
488
P01AB01
ATC
metronidazole; oral, rectal
1.1
6.7
4215
34496
XCK10
NOMESCO Finland
Photography of fundus of eye
0.7
6.7
221
2727
O86.8
ICD-10 Finland
Other specified puerperal infections
2.1
6.6
74
316
2BB01
NOMESCO Finland
NA
17.5
6.6
10
5
J01DA08
ATC
[U] cefaclor; oral
1.2
6.6
1165
8730
Z37.2
ICD-10 Finland
Twins, both liveborn
2.2
6.6
64
257
O03.6
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, complicated by delayed or excessive haemorrhage
1.7
6.6
121
616
6533B
ICD-9 Finland
Disproportion, Outlet contraction of pelvis[PELVIS ANGUSTA, ANOM APERT INFER,SYNNYTYKSEN AIKANA]
0.2
6.6
6
272
O41.9
ICD-10 Finland
Disorder of amniotic fluid and membranes, unspecified
2.1
6.5
69
289
O36.9
ICD-10 Finland
Maternal care for fetal problem, unspecified
1.6
6.4
172
972
R51
ICD-10 Finland
Headache
1.3
6.4
501
3437
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.2
6.4
654
4640
O36.4
ICD-10 Finland
Maternal care for intrauterine death
1.8
6.3
97
468
G03GA02
ATC
human menopausal gonadotrophin; parenteral
1.4
6.3
343
2228
O43.2
ICD-10 Finland
Morbidly adherent placenta
6.6
6.2
15
20
O41.0
ICD-10 Finland
Oligohydramnios
1.4
6.2
342
2232
ZXA00
NOMESCO Finland
Right side
0.8
6.2
1110
11241
MBC90
NOMESCO Finland
Procedure to control bleeding after delivery
7.2
6.2
14
17
2851A
ICD-9 Finland
Other and unspecified anaemias, Acute posthaemorrhagic anaemia
8.1
6.2
13
14
O26.80
ICD-10 Finland
Gingivitis associated with pregnancy
2.6
6.2
42
143
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
1.5
6.2
180
1038
M75.1
ICD-10 Finland
Rotator cuff syndrome
0.9
6.1
1201
12079
R03CC02
ATC
salbutamol; systemic
1.3
6.1
482
3312
PG1PT
NOMESCO Finland
Extensive endovascular embolisation for bleeding with radiological guidance not elsewhere classified
4.5
6.1
20
39
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
0.7
6.1
164
2094
W03
ICPC
Antepartum bleeding
1.6
6.0
138
751
Z36.4
ICD-10 Finland
Antenatal screening for fetal growth retardation using ultrasound and other physical methods
1.4
6.0
257
1604
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.1
6.0
5375
44712
L02AE02
ATC
leuprorelin; implant, parenteral
1.5
6.0
186
1089

Mortality – FinRegistry

Association

Association between endpoint O15_POSTPART_HEAMORRH_LB and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_POSTPART_HEAMORRH_LB.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: O15_POSTPART_HEAMORRH_LB – Postpartum hemorraghe, parous women as controls

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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