Postpartum haemorrhage due to anatomy

O15_POSTPART_HAEMORRH_ANATOMY

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only females

293218

2. Check conditions

None

293218

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O72.1
  • Hospital discharge: ICD-9 6661
  • Cause of death: ICD-10 O72.1
  • Cause of death: ICD-9 6661

2 out of 7 registries used, show all original rules.

4888

4. Check minimum number of events

None

4888

5. Include endpoints

None

4888

6. Filter based on genotype QC (FinnGen only)

4654

Control definitions (FinnGen only)

Control exclude
!(NUMBER_OF_OFFSPRING>0), !(O15_DELIVERY, O15_DELIVERY_PROXY)

Extra metadata

First used in FinnGen datafreeze
DF8

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 29763 29763 -
Only index persons 29492 29492 -
Unadjusted period prevalence (%)
Whole population 0.85 0.85 -
Only index persons 1.08 1.08 -
Median age at first event (years)
Whole population - 30.31 -
Only index persons - 30.30 -

-FinnGen-

Key figures

All Female Male
Number of individuals 4654 4654 -
Unadjusted period prevalence (%) 1.65 1.65 -
Median age at first event (years) 30.75 30.75 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
4888
Matched controls
48880
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
13987.4
307.7
4267
24
O80.8
ICD-10 Finland
Other single spontaneous delivery
3.8
307.7
1450
4876
6661A
ICD-9 Finland
Postpartum haemorrhage, Other immediate postpartum haemorrhage[HAEMORRHAGIA POST PARTUM ATONICA UTERI]
+∞
307.7
454
*
O72.0
ICD-10 Finland
Third-stage haemorrhage
4.3
226.7
656
1711
6661X
ICD-9 Finland
Postpartum haemorrhage, Other immediate postpartum haemorrhage[HAEMORRHAGIA POST PARTUM ACUTA ALIA]
+∞
183.5
175
*
MBA04
NOMESCO Finland
Curettage of uterus after delivery
6.9
164.8
263
402
WW500
NOMESCO Finland
Blood transfusion
4.2
98.0
270
669
O70.1
ICD-10 Finland
Second degree perineal laceration during delivery
2.5
89.8
616
2630
SPAT1373
SPAT
Combined screening in early pregnancy
2.8
86.2
473
1805
SPAT1375
SPAT
Structural ultrasound screening, weeks 18+0-21+6
3.4
84.8
327
1019
O61.8
ICD-10 Finland
Other failed induction of labour
5.7
69.4
131
236
MAX99
NOMESCO Finland
Assistance to normal delivery
1.7
64.5
1762
12137
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
2.9
61.7
308
1113
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
2.7
53.3
306
1189
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
2.5
50.2
325
1339
Z39.2
ICD-10 Finland
Routine postpartum follow-up
1.6
48.9
2542
20056
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
2.5
44.8
299
1249
Z10.8
ICD-10 Finland
Routine general health check-up of other defined subpopulations
2.3
44.3
372
1719
SPAT1197
SPAT
Extensive health check-up of expecting family
1.5
39.4
2446
19669
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
2.3
39.3
308
1381
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
1.5
38.6
2296
18276
O41.8
ICD-10 Finland
Other specified disorders of amniotic fluid and membranes
4.0
34.9
100
255
O71.3
ICD-10 Finland
Obstetric laceration of cervix
6.8
34.8
54
80
SPAT1380
SPAT
Postpartum check-up
1.5
34.7
1897
14755
W92
ICPC
Compl labour/ delivery livebirth
1.9
34.0
443
2405
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
1.6
33.4
959
6496
MBC00
NOMESCO Finland
Repair of obstetric laceration of cervix uteri
6.4
32.4
53
83
SPAT1200
SPAT
Guidance for breast-feeding and breast care
1.8
32.2
511
2953
MBC30
NOMESCO Finland
Repair of partial rupture of perineum
2.0
32.1
347
1764
MBB10
NOMESCO Finland
Packing of delivered uterus
7.6
29.3
41
54
SPAT1379
SPAT
Health check-up of pregnant person
1.4
29.2
2163
17606
8831
FHL
Uterine exploration and / or scraping or suction emptying (ad 24 hours)
5.5
28.1
54
99
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
2.0
27.9
320
1661
W78
ICPC
Pregnancy
1.4
25.1
2769
23835
W90
ICPC
Uncompl labour/delivery livebirth
1.5
24.6
938
6711
SPAT1246
SPAT
Screening of depression or other psychiatric problem
1.6
24.2
577
3716
W85
ICPC
Gestational diabetes
1.5
24.1
745
5097
SPAT1195
SPAT
Antenatal classes
1.6
23.7
555
3557
O73.1
ICD-10 Finland
Retained portions of placenta and membranes, without haemorrhage
2.8
23.0
113
405
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
1.6
22.3
520
3327
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
2.3
21.0
163
728
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.4
19.3
1360
10782
MBC33
NOMESCO Finland
Repair of complete rupture of perineum
2.5
18.4
111
443
O48
ICD-10 Finland
Prolonged pregnancy
1.5
17.5
515
3474
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
1.3
17.3
1383
11143
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
1.3
17.2
2057
17520
O62.3
ICD-10 Finland
Precipitate labour
4.1
16.8
45
110
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
1.6
15.6
431
2863
Z39.1
ICD-10 Finland
Care and examination of lactating mother
1.6
15.4
358
2284
WX600
NOMESCO Finland
Single shot through catheter
1.9
15.2
209
1152
SPAT1189
SPAT
Other ultrasound examination during pregnancy
1.5
15.1
552
3887
Z34
ICD-10 Finland
Supervision of normal pregnancy
1.4
14.9
731
5435
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.0
14.6
165
853
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
1.3
14.2
1150
9240
WX234
NOMESCO Finland
Paracervical blockade
0.6
14.0
187
3270
O47.9
ICD-10 Finland
False labour, unspecified
1.6
13.0
273
1698
MAE00
NOMESCO Finland
Outlet vacuum delivery
1.4
12.8
678
5099
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
1.5
12.2
352
2360
MBA05
NOMESCO Finland
Curettage of uterus after abortion
1.9
11.7
140
741
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
1.8
11.6
175
994
WX307
NOMESCO Finland
Obstetric epidural analgesia
0.8
11.5
1038
12611
6653B
ICD-9 Finland
Other obstetrical trauma, Laceration of cervix
9.2
11.5
23
25
O81.4
ICD-10 Finland
Vacuum extractor delivery
1.3
11.4
784
6128
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.2
11.4
3243
29947
SPAT1324
SPAT
Screening procedure
0.8
11.4
943
11590
PC7NT
NOMESCO Finland
Endovascular occlusion of uteral arteries to stop puerperal bleeding
8.0
11.1
24
30
SPAT1190
SPAT
Insertion or removal of intrauterine contraceptive device
1.3
10.9
729
5674
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
1.4
10.9
467
3385
B01AB05
ATC
enoxaparin; parenteral
1.3
10.4
980
7990
PH2DE
NOMESCO Finland
Ultrasound examination of bloodflow in veins of lower extremity with Doppler method
2.1
10.0
97
477
WX725
NOMESCO Finland
Noninvasive ventilation
0.4
10.0
47
1185
OAA20, ,
SPAT
4.4
9.8
24
55
8834
FHL
Kerviksrupure repair
10.6
9.8
18
17
W29
ICPC
Pregnancy symptom/complaint other
1.4
9.7
438
3202
SPAT1322
SPAT
Pre-employment physical examination
1.8
9.6
134
747
O71.4
ICD-10 Finland
Obstetric high vaginal laceration
2.0
9.2
95
478
N81.6
ICD-10 Finland
Rectocele
1.6
9.2
211
1344
XMA22
NOMESCO Finland
General examination of pregnant woman
0.7
9.1
419
5623
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
2.0
9.1
92
460
ZXD05
NOMESCO Finland
Urgent procedure
1.2
9.0
1671
14642
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
0.7
8.9
222
3328
WX720
NOMESCO Finland
Own respiration
0.4
8.8
40
1023
O41.9
ICD-10 Finland
Disorder of amniotic fluid and membranes, unspecified
2.5
8.7
51
203
MBW96
NOMESCO Finland
Other operation after delivery or abortion
3.3
8.6
31
94
O63.1
ICD-10 Finland
Prolonged second stage (of labour)
1.4
8.3
342
2461
O70.2
ICD-10 Finland
Third degree perineal laceration during delivery
2.1
8.3
73
347
O70.21
ICD-10 Finland
III degree perineal tear involving less than one half of external anal sphincter thickness torn during childbirth
2.4
8.3
53
220
Z75.1
ICD-10 Finland
Person awaiting admission to adequate facility elsewhere
2.2
8.2
65
296
Z01.2
ICD-10 Finland
Dental examination
1.2
8.2
2344
21317
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
1.3
8.2
714
5749
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.4
8.1
298
2100
O70.22
ICD-10 Finland
III degree perineal tear involving one half or more of external anal sphincter thickness torn during childbirth
2.7
8.1
41
152
SPAT1128
SPAT
Instruction of pelvic floor / sphincter exercises
1.8
8.0
111
618
TPH04
NOMESCO Finland
Cathetrisation of vein
0.7
8.0
414
5457
OAA48, ,
SPAT
0.4
8.0
43
1019
SPAT1310
SPAT
Counselling related to known health issue
1.2
8.0
1389
12069
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
1.6
7.9
192
1242
WX704
NOMESCO Finland
Intubation
0.6
7.8
134
2189
D82
ICPC
Teeth/gum disease
1.2
7.8
1980
17799
O42.1
ICD-10 Finland
Premature rupture of membranes, onset of labour after 24 hours
1.7
7.7
144
873
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.3
7.6
465
3565
Z3231
NOMESCO Finland
Registered nurse
0.8
7.6
580
7250
A78
ICPC
Infectious disease other/NOS
0.4
7.6
45
1026
SPAT1389
SPAT
Visit based on need for special support
1.5
7.6
210
1399
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.3
7.6
709
5757
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
1.5
7.5
256
1778
O75.7
ICD-10 Finland
Vaginal delivery following previous caesarean section
2.4
7.5
51
218
ZXA00
NOMESCO Finland
Right side
0.7
7.4
310
4228
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
0.5
7.4
52
1111
K05.31
ICD-10 Finland
Periodontitis pronounced
0.5
7.2
78
1445
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
2.1
7.2
67
326
O75.6
ICD-10 Finland
Delayed delivery after spontaneous or unspecified rupture of membranes
1.5
7.2
254
1778
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
0.6
7.1
110
1841
TLW12
NOMESCO Finland
Insertion of frozen embryo
1.5
7.1
181
1186
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
1.2
7.0
1255
10906
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.2
7.0
1401
12302
O35.9
ICD-10 Finland
Maternal care for (suspected) fetal abnormality and damage, unspecified
1.7
7.0
117
690
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.2
6.9
2197
20056
O47
ICD-10 Finland
False labour
1.6
6.9
133
816
O44.0
ICD-10 Finland
Placenta praevia specified as without haemorrhage
1.8
6.8
97
546
N81.1
ICD-10 Finland
Cystocele
1.6
6.8
162
1046
OAA30, ,
SPAT
3.6
6.7
21
58
A10AB05
ATC
insulin aspart; parenteral
0.5
6.7
74
1361
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.4
6.7
292
2125
8841
FHL
Uterine emptying and scraping (ad 6 weeks)
3.4
6.7
23
68
6660A
ICD-9 Finland
Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM STADII III]
2.5
6.7
39
156
103
Kela drug reimbursment
Diabetes, insulin-treated
0.7
6.6
203
2923
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
1.6
6.5
162
1055
215
Kela drug reimbursment
Diabetes, non-insulin-treated
0.7
6.5
203
2910
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
0.4
6.3
35
816
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
0.8
6.3
929
10817
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
1.7
6.3
102
598
O84.8
ICD-10 Finland
Other multiple delivery
2.5
6.3
38
155
6661B, ,
ICD-9 Finland
+∞
6.2
6
*
RD211, ,
NOMESCO Finland
0.5
6.2
40
880
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
1.2
6.1
2373
21916
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
1.4
6.1
314
2347
A10AB01
ATC
insulin (human); parenteral
0.4
6.1
34
792
W31
ICPC
Pregnancy, Medical examin/health eval partial
0.5
6.1
51
1023
W05
ICPC
Pregnancy vomiting/nausea
1.5
6.1
157
1032
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
2.4
6.1
39
163
E0001A1, ,
ATC
1.6
6.1
118
726

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
680
2999
2.47
92.68
2.3
2.7
33.58
32.80
%
1.15
553
2428
517
2250
2.45
71.63
2.2
2.9
—
—
—
0
0
374
1452
2.71
65.47
1.7
2.2
3.61
3.73
g/l
1.17
349
1360
1616
10989
1.70
61.36
1.8
1.7
—
—
—
0
0
2044
15037
1.62
55.58
1.8
1.8
—
—
—
0
0
3425
38936
0.60
54.23
10.2
11.0
332.72
332.75
g/l
0.07
3400
38671
1249
8520
1.63
43.94
1.5
1.4
—
—
—
0
0
291
1390
2.16
31.76
1.5
1.5
—
—
—
0
0
90
239
3.82
29.70
1.2
1.2
—
—
—
0
0
1396
10740
1.42
25.00
2.5
2.2
—
—
—
0
0
1409
10928
1.41
23.87
1.6
1.4
—
—
—
0
0
918
6586
1.48
23.64
2.2
2.2
—
—
—
0
0
2571
22008
1.35
23.34
2.3
2.0
—
—
—
0
0
111
414
2.72
21.00
1.6
1.6
4.88
5.48
mmol/l
7.21
106
373
54
130
4.19
20.45
1.1
1.0
—
—
—
0
0
2394
20529
1.33
20.23
1.8
1.7
—
—
—
0
0
3651
39269
0.72
20.09
10.0
10.4
14.67
14.34
%
0.81
3604
38736
2543
22170
1.31
18.28
1.9
1.8
—
—
—
0
0
820
10852
0.71
17.69
3.4
3.1
—
—
—
0
0
576
3983
1.51
17.37
1.6
2.0
28.24
28.77
s
1.96
557
3833
2855
25385
1.30
17.21
2.8
2.5
—
—
—
0
0
2643
23593
1.26
13.95
2.1
2.1
—
—
—
0
0
1898
21622
0.80
12.37
2.3
2.3
—
—
—
0
0
262
1636
1.64
12.32
1.3
1.4
16.64
19.20
u/l
0.80
216
1375
139
733
1.92
11.70
1.3
1.4
—
—
—
0
0
1069
12862
0.78
10.81
2.3
2.7
26.07
27.52
u/l
0.94
1022
12317
1299
10967
1.25
10.26
4.0
4.5
1.06
1.03
inr
1.04
467
4136
984
8044
1.28
10.19
2.5
2.4
7930.89
7803.02
u/l
0.04
523
3858
1206
14134
0.81
9.38
2.8
3.0
60.41
62.70
e6/l
0.05
748
8535
58
239
2.44
9.17
1.1
1.1
15.90
11.80
u/ml
0.19
11
51
321
4474
0.70
8.76
2.4
2.3
198.79
247.75
ng/l
0.16
138
1682
91
466
1.97
8.46
3.6
3.4
30.63
26.34
mu/l
0.46
91
447
95
496
1.93
8.35
1.5
1.3
—
—
—
0
0
846
10174
0.80
8.11
3.3
3.2
1.02
1.02
kg/l
0.07
191
1685
20
47
4.27
7.93
1.2
1.2
—
—
—
0
0
618
7684
0.78
7.81
3.1
3.0
7.40
7.39
ph
0.43
154
1612
4635
45285
1.45
7.68
9.9
8.7
—
—
—
0
0
1907
17101
1.19
7.67
1.9
1.9
—
—
—
0
0
2209
24140
0.85
7.61
3.1
3.1
0.00
0.00
estimate
0.27
528
5625
53
235
2.27
7.20
2.5
2.7
37656.60
40087.80
ug/l
0.86
53
235
20
51
3.93
7.15
1.2
1.2
—
—
—
0
0
610
4902
1.28
7.08
1.2
1.2
—
—
—
0
0
2220
24142
0.85
6.90
4.2
4.3
0.00
0.00
estimate
1.34
536
5588
19
48
3.97
6.88
1.3
1.4
—
—
—
0
0
2242
24310
0.86
6.56
3.2
3.2
0.00
0.00
estimate
1.57
534
5525
122
742
1.66
6.53
1.7
2.3
—
—
—
0
0
1123
9722
1.20
6.48
2.0
2.0
2.80
2.52
mg/l
3.88
958
8398
153
994
1.56
6.26
1.2
1.3
1.22
1.23
nmol/l
0.05
137
875
231
1641
1.43
6.10
1.8
1.7
20.99
20.46
s
0.42
196
1307
97
1593
0.60
5.86
4.2
2.9
1.29
1.54
mmol/l
0.31
84
1296
415
5234
0.77
5.79
2.2
2.2
1.14
1.11
e6/l
0.05
236
2839
113
697
1.64
5.77
1.7
2.1
23.95
24.37
mmol/l
1.26
105
652
48
228
2.12
5.59
1.1
1.1
7.27
10.29
u/ml
0.48
21
147
661
7870
0.81
5.55
1.4
1.5
1.30
1.26
mmol/l
0.59
554
6950
104
1655
0.62
5.53
4.0
2.8
—
7.38
—
0
12
99
1580
0.62
5.34
1.2
1.3
—
—
—
0
0
912
10494
0.84
5.30
2.4
2.6
32.06
73.62
e6/l
1.64
676
7719
312
4037
0.76
5.29
1.4
1.4
—
—
—
0
0
587
4869
1.23
5.16
3.0
3.1
—
—
—
0
0
341
4328
0.77
5.00
1.2
1.2
—
—
—
0
0
1283
11518
1.15
4.54
3.7
4.0
1.21
1.22
mmol/l
1.20
1149
10687
69
1140
0.60
4.36
8.0
6.2
—
—
—
0
0
1763
19027
0.89
4.01
2.8
2.9
6.01
6.02
ph
0.08
186
2022
827
9393
0.86
3.99
2.4
2.5
0.22
0.24
e6/l
0.09
604
6857
1689
18262
0.89
3.94
7.6
7.0
0.00
0.00
e9/l
1.39
1446
15344
1055
9425
1.15
3.93
2.0
2.1
12.11
21.25
ng/l
2.58
314
2838
238
3045
0.77
3.76
2.4
2.1
33.04
34.95
u/l
0.33
206
2602
417
4990
0.82
3.66
2.2
2.3
4.91
5.08
e6/l
0.09
235
2612
413
3431
1.22
3.62
2.0
2.3
5.08
4.68
umol/l
0.59
265
2536
360
2953
1.24
3.56
1.8
1.9
3.86
4.45
e9/l
2.56
288
2663
163
1205
1.36
3.55
1.3
1.3
2.88
6.59
u/ml
0.68
21
123
61
368
1.67
3.54
1.1
1.2
2.30
24.54
u/ml
—
10
37
71
1100
0.64
3.48
3.1
2.1
138.53
54.87
ng/l
0.87
63
957
88
584
1.52
3.44
1.2
1.4
—
3080.00
—
0
8
851
9541
0.87
3.40
2.3
2.4
—
—
—
0
0
779
8765
0.87
3.27
4.3
5.1
—
—
—
0
0
147
1085
1.37
3.27
2.5
2.3
1.08
1.13
g/l
0.36
131
966
165
1249
1.33
3.12
2.7
2.7
—
—
—
0
0
163
1232
1.33
3.12
1.3
1.3
5.49
8.67
u/ml
0.51
30
193
3385
32690
1.12
3.09
4.2
4.0
1474.75
1180.98
e6/l
0.08
28
343
1566
16796
0.90
2.94
4.0
4.3
8.87
9.26
umol/l
1.89
1462
15707
49
298
1.65
2.83
2.0
2.1
—
—
—
0
0
113
1534
0.73
2.79
1.6
1.8
—
—
—
0
0
25
125
2.01
2.70
1.1
1.1
4.31
0.84
u/ml
0.46
17
83
320
3804
0.83
2.67
1.9
2.1
5.64
5.60
umol/l
0.02
264
3166
2517
26290
0.91
2.64
5.7
5.7
68.47
69.18
u/l
0.58
2331
24836
815
9019
0.88
2.63
1.6
1.6
—
—
—
0
0
381
4438
0.85
2.53
2.0
2.1
2.39
2.39
mmol/l
0.02
325
3820
4810
47779
1.42
2.48
14.3
13.5
7.31
6.95
e9/l
18.01
4753
46983
30
165
1.82
2.48
1.4
1.4
—
—
—
0
0
4809
47771
1.41
2.44
14.2
13.4
29.93
29.94
pg
0.27
4777
47502
883
8033
1.12
2.43
2.1
2.0
2582.23
1441.84
umol/l
0.51
802
7374
4809
47772
1.41
2.43
14.2
13.4
89.66
89.71
fl
0.45
4777
47504
505
5735
0.87
2.42
3.8
4.0
16.13
14.91
mg/mmol
0.21
337
3901
9
222
0.40
2.41
1.2
1.3
4.24
4.90
u/l
—
9
187
485
5522
0.86
2.41
3.2
3.4
628.80
488.27
mg/l
0.22
333
3732
4800
47672
1.38
2.38
14.1
13.3
39.79
39.59
%
0.07
4695
45621
417
3611
1.17
2.38
2.0
2.2
223.73
342.61
ng/l
1.98
302
2816
4809
47777
1.41
2.37
14.2
13.4
4.37
4.44
e12/l
26.15
4750
47026
141
1804
0.78
2.34
2.5
2.5
—
—
—
0
0
16
71
2.26
2.34
1.1
1.0
0.78
0.09
u/ml
—
7
35
666
7397
0.88
2.28
2.0
2.2
8.11
9.63
e6/l
1.43
580
6427
4810
47798
1.40
2.27
14.4
13.5
130.18
132.15
g/l
27.63
4779
47521
149
1171
1.28
2.24
1.6
2.3
7.43
7.42
ph
0.56
13
178
4804
47732
1.38
2.23
14.3
13.5
254.46
265.66
e9/l
34.09
4748
47000
697
7706
0.89
2.22
3.2
3.2
7.70
7.86
mmol/l
0.38
638
6969
61
879
0.69
2.21
1.8
2.2
—
—
—
0
0
25
136
1.84
2.17
1.7
2.3
—
—
—
0
0
86
1164
0.73
2.16
1.3
1.3
141.30
104.22
u/ml
0.33
22
312
1139
12252
0.91
2.16
3.6
3.8
37.07
37.04
g/l
0.05
1049
11468
150
1187
1.27
2.15
1.6
2.3
4.90
5.02
kpa
1.52
141
1131
15
68
2.21
2.10
1.1
1.0
0.17
0.17
u/ml
—
7
30
302
2576
1.18
2.10
1.2
1.2
9.81
9.85
u/l
0.02
264
2206
201
2436
0.82
2.10
2.7
3.0
—
—
—
0
0
117
1504
0.77
2.06
8.9
6.3
—
—
—
0
0
80
1082
0.74
2.02
1.1
1.2
267.90
242.38
u/ml
0.39
48
764
120
1531
0.78
2.00
4.0
2.7
—
—
—
0
0
99
1288
0.76
1.93
1.3
1.1
—
—
—
0
0
264
2246
1.19
1.92
1.5
1.7
—
—
—
0
0
170
1387
1.23
1.91
1.3
1.3
23.19
29.41
u/ml
—
8
101
0
50
0.00
1.88
0.0
1.8
—
1.19
—
0
45
0
51
0.00
1.88
0.0
1.4
—
50.10
—
0
31
5
140
0.36
1.87
18.8
13.6
1209.80
1192.25
nmol/l
—
5
130
3383
32984
1.08
1.85
4.0
4.0
—
—
—
0
0
146
1177
1.25
1.84
1.3
1.2
—
—
—
0
0
306
3521
0.86
1.80
2.0
2.0
—
—
—
0
0
902
9731
0.91
1.80
2.2
2.6
2.33
2.34
mmol/l
0.41
798
8939
15
73
2.06
1.80
1.1
1.0
0.03
0.06
u/ml
—
9
36
1040
9693
1.09
1.78
1.8
1.7
1.13
0.92
mg/l
1.44
789
7149
447
3988
1.13
1.74
1.6
1.6
1086.12
1212.02
nmol/l
2.04
349
3226
159
1308
1.22
1.69
1.1
1.1
1.74
1.66
u/ml
0.04
69
612
1245
13203
0.92
1.67
3.3
3.3
0.01
0.00
estimate
0.62
523
5521
84
1091
0.77
1.66
3.4
4.5
—
—
—
0
0
483
4346
1.12
1.65
1.2
1.1
—
—
—
0
0
97
1234
0.78
1.63
1.3
1.3
—
—
—
0
0
140
1142
1.23
1.62
1.9
2.7
0.40
0.31
g/l
0.44
56
494
53
734
0.72
1.62
1.1
1.1
—
—
—
0
0
5
133
0.38
1.61
18.0
10.3
780.40
678.08
nmol/l
—
5
126
9
190
0.47
1.60
1.9
2.0
24.11
28.40
%
—
9
185
104
821
1.27
1.60
3.9
3.1
—
—
—
0
0
116
928
1.26
1.60
1.1
1.1
0.09
0.28
u/ml
0.69
20
228
8
32
2.50
1.59
1.1
1.9
—
—
—
0
0
19
325
0.58
1.57
1.7
2.8
—
—
—
0
0
326
2873
1.14
1.56
1.3
1.3
69.21
32.92
au/ml
—
10
121
17
296
0.57
1.51
1.1
1.5
1.78
1.22
promille
—
10
226
626
6805
0.91
1.48
2.2
2.3
530.05
530.97
mosm/kgh2o
0.03
526
5727
10
203
0.49
1.46
2.3
2.0
6.80
8.31
%
—
10
197
131
1075
1.22
1.46
1.3
1.3
—
—
—
0
0
42
293
1.44
1.45
1.1
1.4
4.24
6.31
ug/l
2.45
34
261
9
38
2.37
1.45
1.1
1.1
—
—
—
0
0
92
726
1.27
1.45
1.2
1.4
—
1.50
—
0
14
17
95
1.79
1.42
1.1
1.1
—
—
—
0
0
20
327
0.61
1.41
9.5
11.9
0.63
0.59
mmol/l
0.72
20
302
39
553
0.70
1.40
2.9
3.6
29.51
22.23
u/ml
0.43
39
534
9
178
0.50
1.39
1.0
1.7
—
—
—
0
0
396
3563
1.12
1.39
1.2
1.3
198.51
161.24
u/ml
0.43
373
3308
657
7099
0.91
1.38
1.6
1.5
—
—
—
0
0
78
991
0.78
1.35
1.2
1.3
16.74
21.59
e6/l
0.19
61
772
78
990
0.78
1.34
1.3
1.4
239.41
1508.68
e6/l
1.16
63
822
226
2592
0.87
1.34
3.7
3.6
0.54
0.59
%
0.10
49
568
30
442
0.68
1.34
1.8
1.6
—
—
—
0
0
3695
37562
0.93
1.30
2.9
3.0
2.86
2.87
mmol/l
0.68
3475
35965
51
378
1.35
1.28
1.7
1.5
—
—
—
0
0
96
1181
0.81
1.27
1.6
1.7
5.73
4.17
ug/l
0.34
86
1038
659
7086
0.92
1.25
1.6
1.5
—
—
—
0
0
1388
13254
1.07
1.24
4.4
4.5
1.21
1.22
mmol/l
3.07
1167
11243
248
2808
0.88
1.24
3.9
3.7
1.16
0.92
%
0.36
53
657
56
425
1.32
1.22
1.0
1.0
—
—
—
0
0
230
2612
0.87
1.21
3.9
3.8
0.08
0.38
%
0.65
39
472
109
899
1.22
1.21
1.3
1.2
3.09
4.48
u/ml
1.09
45
356
145
1704
0.85
1.20
6.4
6.3
96.92
97.02
%
0.06
139
1625
151
1285
1.18
1.20
1.1
1.1
2.33
1.02
u/ml
0.39
55
514
103
846
1.22
1.19
1.4
1.3
—
—
—
0
0
2767
26991
1.06
1.19
3.2
3.0
57.28
54.21
ug/l
0.67
2558
25756
673
7208
0.92
1.16
1.6
1.5
—
—
—
0
0
96
785
1.23
1.16
3.3
3.5
58.25
57.56
%
0.29
96
785
0
33
0.00
1.16
0.0
1.0
—
—
—
0
0
4309
42648
1.09
1.13
8.5
8.8
17.71
17.68
mg/l
0.03
3453
33194
436
3998
1.10
1.11
1.3
1.3
—
—
—
0
0
241
2710
0.88
1.11
3.9
3.8
0.26
0.15
%
0.47
46
561
516
5573
0.92
1.10
1.4
1.5
—
—
—
0
0
321
3547
0.90
1.10
2.3
2.1
—
—
—
0
0
42
559
0.75
1.08
2.7
2.8
—
—
—
0
0
104
866
1.21
1.07
1.1
1.1
117.29
117.11
%
0.03
97
790
324
3573
0.90
1.07
2.4
2.1
—
—
—
0
0
341
3096
1.11
1.07
2.3
2.3
25.46
22.17
au/ml
0.17
26
321
33
454
0.73
1.06
1.2
1.4
—
—
—
0
0
17
105
1.62
1.05
5.7
2.2
109.64
5224.59
mg/l
1.06
11
76
78
955
0.81
1.04
7.9
7.3
—
—
—
0
0
324
3564
0.90
1.03
2.3
2.0
—
—
—
0
0
7
34
2.06
1.02
1.0
1.1
1.13
1.29
umol/24h
—
7
34
22
323
0.68
1.02
1.6
1.4
—
—
—
0
0
156
1353
1.16
1.02
1.1
1.2
—
—
—
0
0
127
1084
1.18
1.01
1.1
1.1
5.51
4.53
u/ml
0.20
46
443
37
273
1.36
1.00
1.5
1.3
9.31
9.04
umol/l
0.17
37
262
128
1490
0.86
0.99
4.9
6.1
5.86
6.07
mmol/l
0.19
120
1445
294
3242
0.90
0.99
2.5
2.1
—
—
—
0
0
33
446
0.74
0.96
1.0
1.1
—
—
—
0
0
11
62
1.78
0.94
1.1
1.1
—
—
—
0
0
11
62
1.78
0.94
1.1
1.1
—
—
—
0
0
11
62
1.78
0.94
1.1
1.1
—
—
—
0
0
133
1149
1.16
0.93
1.1
1.1
5.14
4.63
u/ml
0.09
56
534
27
373
0.72
0.91
6.4
2.6
—
—
—
0
0
6
28
2.14
0.91
1.0
1.1
—
—
—
0
0
316
2887
1.10
0.91
1.2
1.2
3.52
3.73
ug/l
0.35
293
2761
25
349
0.71
0.90
5.4
5.2
359.05
364.74
umol/l
0.06
20
297
199
2229
0.89
0.90
2.8
2.8
1.22
1.23
mmol/l
0.29
168
1925
2133
21890
0.95
0.89
5.9
6.6
3.90
4.01
e9/l
1.44
1888
19347
145
1656
0.87
0.89
7.2
5.2
1.36
1.24
mmol/l
0.45
139
1620
684
6463
1.07
0.87
2.8
3.1
—
—
—
0
0
14
217
0.64
0.87
1.8
2.5
—
—
—
0
0
37
282
1.31
0.84
1.1
1.1
290.03
297.64
mg/l
0.28
30
264
63
514
1.23
0.84
1.2
1.1
1.05
1.05
ratio
0.06
22
192
189
1690
1.12
0.83
2.3
2.2
3.82
4.24
iu/l
0.37
76
732
28
205
1.37
0.83
1.2
1.2
—
—
—
0
0
29
388
0.75
0.82
1.2
3.6
5.83
6.34
mmol/l
0.92
23
301
27
197
1.37
0.82
1.6
2.5
—
—
—
0
0
90
764
1.18
0.81
1.5
1.3
—
—
—
0
0
54
436
1.24
0.80
1.5
1.6
—
—
—
0
0
60
730
0.82
0.80
2.6
4.1
—
—
—
0
0
3688
37325
0.95
0.80
2.8
2.9
4.74
4.76
mmol/l
1.04
3495
35939
1051
10944
0.95
0.79
2.2
2.2
53.40
56.09
u/l
1.20
958
10237
2227
21754
1.04
0.79
3.3
3.6
5.96
6.01
mmol/l
0.63
1712
18394
3049
30985
0.96
0.78
3.2
3.4
35.72
36.26
mmol/mol
4.19
2872
29556
3671
37147
0.95
0.77
2.8
2.9
1.52
1.54
mmol/l
1.99
3479
35747
120
1371
0.87
0.77
1.5
1.4
28.61
32.54
nmol/l
1.03
105
1282
32
243
1.32
0.77
1.2
1.4
22.23
25.42
umol/l
0.28
27
233
45
359
1.26
0.75
1.1
1.4
1198.07
389.28
mu/l
0.80
45
345
714
6795
1.06
0.74
2.7
2.5
106.98
94.34
ug/g
0.59
527
5320
425
4538
0.93
0.74
1.4
1.5
411.30
284.32
mu/l
0.67
361
4032
16
231
0.69
0.73
5.9
3.0
—
—
—
0
0
173
1554
1.12
0.73
1.2
1.1
3.24
2.21
u/ml
0.39
80
755
54
655
0.82
0.72
1.4
2.1
131.67
131.42
g/l
0.03
33
537
461
4335
1.07
0.71
1.9
2.0
2.54
2.55
g/l
0.11
413
3988
46
374
1.23
0.67
1.1
1.4
72.68
72.60
%
0.01
46
360
690
6583
1.06
0.67
1.3
1.4
593.70
605.88
titre
0.05
146
1272
7
43
1.63
0.66
1.0
1.1
9.57
10.04
pmol/l
—
7
43
103
902
1.14
0.66
1.1
1.1
2.52
10.91
au/ml
—
9
66
124
1100
1.13
0.66
1.3
1.3
—
—
—
0
0
3812
38492
0.96
0.65
6.7
7.3
3.87
3.87
mmol/l
0.33
3636
37314
16
112
1.43
0.63
3.4
3.1
—
—
—
0
0
86
987
0.87
0.63
1.1
1.1
—
—
—
0
0
6
101
0.59
0.62
1.2
1.5
—
—
—
0
0
180
1972
0.91
0.61
6.1
6.0
-0.19
0.43
mmol/l
1.13
123
1417
3804
38394
0.96
0.61
6.7
7.3
139.29
139.38
mmol/l
1.69
3654
37329
2838
28801
0.97
0.60
3.4
3.4
8.42
8.35
mm/h
0.15
2607
27251
0
20
0.00
0.60
0.0
1.0
—
7.83
—
0
7
49
408
1.20
0.59
1.1
1.1
1281.75
1452.59
miu/ml
0.61
49
408
214
1972
1.09
0.58
1.4
1.3
—
—
—
0
0
30
237
1.27
0.58
2.6
3.2
1.68
1.47
g/24h
0.21
17
140
404
3816
1.06
0.57
3.7
3.5
4.54
4.62
pmol/l
1.14
356
3490
405
4283
0.94
0.57
1.5
1.7
—
—
—
0
0
463
4394
1.06
0.56
1.2
1.2
—
—
—
0
0
575
5492
1.05
0.56
1.3
1.3
129.05
153.05
iu/ml
0.81
210
2225
16
218
0.73
0.56
1.8
1.7
39.61
45.58
%
—
9
127
35
429
0.81
0.56
1.1
1.5
—
—
—
0
0
3574
36094
0.96
0.55
4.8
4.4
14.17
14.14
pmol/l
0.24
3317
34234
180
1959
0.92
0.55
6.2
6.0
4.84
4.86
kpa
0.12
173
1874
180
1959
0.92
0.55
6.2
6.0
15.15
14.44
kpa
0.62
172
1875
152
1384
1.10
0.54
1.1
1.1
6.54
5.92
u/ml
0.19
69
733
147
1339
1.10
0.53
1.9
2.0
67.96
67.67
g/l
0.19
137
1257
9
132
0.68
0.51
2.0
3.0
—
—
—
0
0
6
40
1.50
0.51
1.3
1.2
70.00
81.80
ng/l
—
6
40
12
168
0.71
0.50
1.8
1.5
119.27
121.64
nmol/l
0.07
12
168
230
2144
1.08
0.50
1.3
1.3
—
—
—
0
0
45
380
1.19
0.49
1.3
1.2
—
—
—
0
0
17
224
0.76
0.49
1.2
1.2
—
—
—
0
0
12
167
0.72
0.49
2.5
1.7
106.92
106.22
mmol/l
0.37
12
167
827
7998
1.04
0.49
2.5
2.8
99.57
99.65
%
0.04
799
7729
7
45
1.56
0.49
1.0
1.4
48.14
78.75
mu/l
—
7
36
37
443
0.83
0.48
1.7
1.2
—
0.13
nmol/l
—
0
7
26
323
0.80
0.48
1.3
1.3
—
—
—
0
0
12
166
0.72
0.47
2.5
1.7
3.96
3.89
mmol/l
0.36
12
166
379
3601
1.06
0.47
1.4
1.3
—
—
—
0
0
567
5444
1.05
0.47
1.3
1.3
22.72
21.71
iu/l
0.33
516
4777
32
387
0.83
0.47
1.8
1.2
—
—
—
0
0
7
48
1.46
0.46
1.0
1.1
—
—
—
0
0
195
2094
0.93
0.46
1.2
1.3
0.43
0.95
u/ml
—
6
163
14
187
0.75
0.45
1.5
1.7
—
—
—
0
0
10
141
0.71
0.44
3.6
3.2
54.78
42.50
umol/l
—
10
131
3512
35425
0.97
0.44
2.6
2.7
1.09
1.11
mmol/l
1.02
3324
34031
50
433
1.16
0.43
1.0
1.1
1.36
1.42
g/l
0.86
41
402
1910
18782
1.03
0.42
4.6
4.7
56.63
56.55
%
0.13
1782
17772
38
446
0.85
0.42
1.1
1.3
0.40
0.38
g/l
0.19
28
311
38
446
0.85
0.42
1.1
1.3
3.08
3.08
g/l
0.00
26
309
47
542
0.87
0.42
1.0
1.2
29.23
35.97
mg/l
1.18
39
450
222
2086
1.07
0.41
2.2
2.4
1.63
1.64
%
0.04
193
1863
39
456
0.85
0.41
1.3
1.3
—
—
—
0
0
48
552
0.87
0.41
2.2
1.9
0.54
1.37
ug/l
1.67
41
493
164
1763
0.93
0.41
1.1
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.6
—
168.20
—
0
15
0
15
0.00
0.41
0.0
1.0
—
0.01
—
0
5
0
15
0.00
0.41
0.0
1.0
—
0.30
—
0
7
0
16
0.00
0.41
0.0
5.2
—
—
—
0
0
0
16
0.00
0.41
0.0
2.5
—
—
—
0
0
1240
12681
0.97
0.41
1.3
1.3
1.31
1.50
u/ml
0.22
338
3902
12
161
0.74
0.41
2.5
1.7
—
—
—
0
0
1883
19141
0.97
0.41
4.7
4.9
0.50
0.51
e9/l
2.12
1690
17110
65
731
0.89
0.40
1.2
1.2
295.72
340.40
ug/g
0.83
25
329
5
34
1.47
0.40
1.0
1.0
—
—
—
0
0
12
88
1.36
0.40
1.0
1.0
—
—
—
0
0
28
232
1.21
0.39
1.2
1.8
1.56
2.80
u/field
1.31
16
131
34
400
0.85
0.39
1.8
1.2
—
—
nmol/l
—
0
0
24
292
0.82
0.39
1.0
1.1
—
—
—
0
0
1964
19944
0.97
0.39
4.7
5.0
0.18
0.18
e9/l
0.55
1770
18095
0
19
0.00
0.39
0.0
2.4
—
402.84
—
0
19
0
19
0.00
0.39
0.0
4.2
—
—
—
0
0
4263
42834
0.96
0.39
6.9
7.3
22.80
23.23
u/l
0.71
4094
41636
1935
19053
1.03
0.38
4.8
4.9
30.17
30.01
%
0.32
1805
18050
677
6984
0.96
0.38
1.3
1.3
—
—
—
0
0
392
3756
1.05
0.38
2.0
2.0
24.64
24.67
%
0.01
340
3206
46
526
0.87
0.38
1.0
1.1
176.95
193.97
mg/l
0.81
38
463
147
1367
1.08
0.38
3.0
2.4
72.76
71.09
e9/l
0.19
108
967
509
4908
1.04
0.37
1.9
2.0
14.90
15.16
umol/l
0.36
462
4583
62
694
0.89
0.37
2.1
2.9
1.19
1.21
mg/l
0.10
56
667
62
553
1.12
0.37
1.9
2.3
2.21
1.93
mmol/l
0.25
25
296
84
763
1.10
0.36
3.6
3.2
24.63
22.93
mg/l
0.15
41
462
28
332
0.84
0.36
1.6
2.1
—
—
—
0
0
32
272
1.18
0.36
1.0
1.0
—
—
—
0
0
35
300
1.17
0.36
1.0
1.0
—
—
—
0
0
5
78
0.64
0.35
1.6
1.4
137.57
93.54
nmol/l
—
5
57
32
374
0.85
0.35
1.2
1.2
—
—
—
0
0
16
201
0.80
0.35
1.1
1.1
—
—
—
0
0
19
153
1.24
0.35
1.2
1.0
1.09
0.88
u/ml
0.13
12
131
25
298
0.84
0.34
4.4
2.9
36.62
26.45
mg/l
0.27
17
241
375
3904
0.96
0.34
1.3
1.3
—
—
—
0
0
6
44
1.36
0.34
1.5
1.4
0.67
1.16
u/field
—
6
44
39
447
0.87
0.34
1.1
1.3
—
—
—
0
0
1891
19180
0.98
0.34
4.7
4.9
0.04
0.04
e9/l
0.66
1687
17090
195
1842
1.06
0.33
1.1
1.1
2.07
4.76
u/ml
2.00
28
307
39
446
0.87
0.33
1.1
1.3
7.03
6.50
g/l
0.51
29
311
368
3828
0.96
0.33
2.4
2.7
0.84
0.84
mmol/l
0.33
346
3641
12
155
0.77
0.33
1.0
1.1
—
—
—
0
0
62
558
1.11
0.33
1.6
2.0
156.40
196.96
ug/l
0.26
49
466
6
46
1.30
0.33
1.3
1.1
—
—
—
0
0
70
770
0.91
0.32
1.1
1.1
104.88
11861.33
iu/ml
0.63
34
226
31
266
1.17
0.32
1.1
1.1
—
—
—
0
0
36
313
1.15
0.32
2.1
2.2
43.56
43.48
%
0.01
36
306
1842
18165
1.02
0.32
5.1
5.1
7.43
7.61
%
2.04
1708
17153
13
101
1.29
0.31
1.4
1.2
—
—
—
0
0
1106
11279
0.97
0.31
1.7
1.6
100.16
99.54
pmol/l
0.19
655
6433
7
96
0.73
0.30
1.7
1.5
—
—
—
0
0
451
4662
0.96
0.30
1.5
1.5
—
—
—
0
0
27
315
0.86
0.30
6.9
2.6
70.66
62.76
%
1.26
27
315
262
2738
0.95
0.30
2.6
2.2
—
—
—
0
0
111
1034
1.08
0.30
1.1
1.1
3.75
3.13
u/ml
0.13
54
558
148
1395
1.06
0.29
2.0
2.0
0.23
0.22
g/l
0.40
141
1324
8
106
0.75
0.29
1.1
1.1
—
—
—
0
0
42
373
1.13
0.29
1.5
1.9
—
—
—
0
0
120
1124
1.07
0.28
1.1
1.1
—
—
—
0
0
20
167
1.20
0.28
1.5
1.5
893.44
19004.53
e6/l
—
9
119
264
2753
0.96
0.28
1.1
1.1
—
—
—
0
0
120
1125
1.07
0.28
1.1
1.1
—
—
—
0
0
376
3890
0.96
0.28
2.0
1.9
389.45
378.93
nmol/l
0.54
354
3612
735
7521
0.97
0.27
1.6
1.8
144.65
132.99
u/l
0.19
696
7163
30
261
1.15
0.27
1.4
1.8
39.76
42.48
%
0.15
21
153
9
116
0.78
0.27
1.0
1.1
—
—
—
0
0
586
6014
0.97
0.27
1.4
1.4
21.47
20.97
nmol/l
0.43
513
5409
1323
13437
0.98
0.27
2.1
2.2
—
—
—
0
0
195
1859
1.05
0.27
1.6
1.7
—
—
—
0
0
30
262
1.15
0.26
1.2
1.1
—
—
—
0
0
10
77
1.30
0.26
1.1
1.4
—
6.12
—
0
5
282
2928
0.96
0.26
1.2
1.2
—
—
—
0
0
152
1442
1.06
0.25
2.0
2.0
1.17
1.16
g/l
0.28
146
1371
34
301
1.13
0.25
1.0
1.4
—
—
—
0
0
26
298
0.87
0.25
4.2
2.9
26.64
45.43
mg/l
0.61
17
241
223
2321
0.96
0.23
1.2
1.2
—
—
—
0
0
930
9460
0.98
0.23
1.5
1.5
—
—
—
0
0
1824
18046
1.02
0.23
4.8
4.9
2.73
2.74
%
0.08
1685
16973
52
567
0.92
0.22
1.0
1.0
—
—
—
0
0
293
3029
0.97
0.22
1.1
1.1
98.75
230.06
titre
—
8
88
7
94
0.74
0.22
2.1
2.1
152.29
156.65
nmol/l
—
7
85
7
95
0.74
0.22
2.1
2.3
15.62
21.53
ug/l
—
7
95
1547
15648
0.98
0.21
2.2
2.1
74.99
73.07
nmol/l
2.26
1438
14818
0
11
0.00
0.21
0.0
1.0
—
0.12
—
0
5
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.7
—
36.60
—
0
10
0
12
0.00
0.21
0.0
1.0
—
0.18
—
0
6
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
43
471
0.91
0.21
1.3
1.8
17.75
17.29
%
0.45
16
218
2938
29196
1.02
0.21
2.5
2.5
26.90
28.80
u/l
1.29
2819
28123
18
209
0.86
0.21
1.1
1.0
—
—
—
0
0
30
335
0.89
0.20
1.3
1.2
—
—
—
0
0
613
6255
0.98
0.20
1.4
1.5
9176443.01
55127235.78
pmol/l
3.45
534
5520
0
14
0.00
0.20
0.0
1.3
—
91.11
—
0
9
18
208
0.86
0.20
4.9
2.0
—
—
—
0
0
6
49
1.22
0.20
1.0
1.3
305.33
347.23
pmol/l
—
6
39
30
334
0.90
0.20
1.1
1.1
—
—
—
0
0
90
849
1.06
0.20
1.2
1.2
—
—
—
0
0
60
645
0.93
0.20
1.5
1.5
0.61
0.57
g/l
0.23
48
494
128
1342
0.95
0.20
2.2
2.2
—
—
—
0
0
122
1162
1.05
0.19
1.2
1.3
21.77
36.15
u/ml
—
9
106
86
911
0.94
0.19
1.2
1.3
—
—
—
0
0
41
375
1.09
0.19
1.0
1.0
—
—
—
0
0
23
203
1.13
0.19
1.1
1.5
4.25
2.47
u/field
0.42
16
146
1421
14364
0.98
0.18
2.6
2.7
—
—
—
0
0
260
2677
0.97
0.18
3.8
4.5
1.05
1.04
mmol/l
0.10
243
2533
348
3566
0.97
0.17
1.3
1.3
241.94
236.91
miu/ml
0.10
191
1848
243
2503
0.97
0.17
3.3
3.0
—
—
—
0
0
13
110
1.18
0.17
1.2
1.3
6.33
6.20
mmol/l
0.10
13
103
58
543
1.07
0.17
2.4
1.9
6.37
5.33
mmol/24h
1.16
51
499
39
359
1.09
0.16
1.1
1.1
4.29
9.01
iu/ml
—
10
96
24
215
1.12
0.16
1.3
1.1
6.78
5.76
nmol/l
0.68
24
207
29
263
1.10
0.16
3.0
2.7
793.24
860.36
e6/l
0.41
29
256
3611
35976
1.01
0.16
2.8
2.9
5.38
5.43
mmol/l
3.50
3336
34065
4002
40137
0.98
0.16
5.2
5.0
1.60
1.75
mu/l
1.42
3741
38490
14
162
0.86
0.16
1.0
1.3
—
—
—
0
0
37
401
0.92
0.16
1.4
1.6
—
—
—
0
0
305
3124
0.97
0.15
2.5
2.6
—
—
—
0
0
6
76
0.79
0.15
1.7
1.5
—
—
—
0
0
6
80
0.75
0.15
1.2
1.6
—
—
—
0
0
32
348
0.92
0.15
1.1
1.1
—
—
—
0
0
24
217
1.11
0.14
2.2
2.5
—
—
—
0
0
7
89
0.79
0.14
1.1
1.1
—
—
—
0
0
100
959
1.04
0.14
1.3
1.3
1386.67
1015.48
titre
—
6
42
14
160
0.87
0.14
1.1
2.2
104.25
223.04
umol/l
—
8
82
20
179
1.12
0.14
1.4
1.2
—
—
—
0
0
1008
10189
0.99
0.14
1.3
1.4
2.02
2.04
g/l
0.16
631
6606
36
334
1.08
0.13
1.9
2.0
—
—
—
0
0
102
980
1.04
0.13
1.3
1.3
128.33
109.25
titre
—
6
93
9
106
0.85
0.13
1.0
1.2
—
—
—
0
0
1824
18126
1.01
0.12
5.3
5.3
—
—
—
0
0
15
167
0.90
0.10
1.1
1.2
—
—
—
0
0
857
8649
0.99
0.10
1.3
1.3
20.12
22.65
iu/ml
0.24
247
2749
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
21
193
1.09
0.10
2.3
1.6
—
—
—
0
0
49
514
0.95
0.09
1.1
1.0
0.30
1.18
u/ml
—
9
126
50
524
0.95
0.09
3.0
3.2
1595.86
101.55
u/ml
0.66
42
444
129
1256
1.03
0.09
1.1
1.1
—
—
—
0
0
10
114
0.88
0.09
1.3
1.3
—
0.30
g/l
—
0
5
10
114
0.88
0.09
1.0
1.0
—
—
—
0
0
54
517
1.04
0.09
1.3
1.2
—
—
—
0
0
1651
16424
1.01
0.09
1.9
2.0
—
—
—
0
0
87
898
0.97
0.09
1.2
1.3
—
—
—
0
0
90
928
0.97
0.09
1.9
1.8
—
—
—
0
0
38
400
0.95
0.08
1.2
1.2
3.29
1.71
u/ml
0.31
19
204
20
216
0.93
0.08
1.1
1.3
—
—
—
0
0
13
144
0.90
0.08
1.2
1.4
—
—
—
0
0
10
113
0.88
0.08
1.6
1.4
—
—
—
0
0
34
322
1.06
0.08
1.7
2.1
13.82
12.47
%
0.45
34
316
5
65
0.77
0.08
2.0
1.5
—
—
—
0
0
115
1179
0.97
0.08
2.3
2.1
—
—
—
0
0
49
511
0.96
0.08
1.1
1.1
0.40
1.80
u/ml
1.11
13
167
207
2034
1.02
0.08
1.6
1.8
1.20
1.37
g/l
2.19
187
1914
22
236
0.93
0.08
1.4
1.2
300.00
179.57
titre
—
6
47
25
234
1.07
0.08
1.1
1.1
5.50
42.81
u/ml
0.44
13
133
7
66
1.06
0.08
1.0
1.2
—
—
—
0
0
26
244
1.07
0.08
3.2
3.1
7.93
7.79
mg/l
0.05
15
192
192
1887
1.02
0.07
1.7
1.7
—
—
—
0
0
1993
20004
0.99
0.07
4.6
4.9
1.96
1.99
e9/l
0.25
1820
18338
8
77
1.04
0.07
1.1
1.2
—
—
—
0
0
65
671
0.97
0.07
1.0
1.1
—
—
—
0
0
17
157
1.08
0.07
2.5
2.0
—
—
—
0
0
12
132
0.91
0.06
1.0
1.0
—
—
—
0
0
12
132
0.91
0.06
1.0
1.0
—
—
—
0
0
12
132
0.91
0.06
1.0
1.0
—
—
—
0
0
146
1487
0.98
0.06
3.2
3.0
60.07
70.34
ng/l
1.55
135
1361
17
183
0.93
0.06
1.2
1.4
75.41
93.03
nmol/24h
0.66
17
183
292
2954
0.99
0.06
1.2
1.2
—
—
—
0
0
45
467
0.96
0.06
1.8
1.7
6533.21
8343.12
e6/l
0.41
38
338
12
109
1.10
0.06
1.8
2.6
—
—
—
0
0
29
276
1.05
0.06
7.2
6.3
—
—
—
0
0
26
273
0.95
0.05
1.3
1.3
65.00
66.06
umol/l
0.19
26
273
11
120
0.92
0.05
1.0
1.0
—
—
—
0
0
1734
17294
1.00
0.04
4.9
5.0
0.66
0.66
%
0.04
1589
16157
13
140
0.93
0.04
1.1
1.2
—
—
—
0
0
302
2996
1.01
0.04
1.9
2.1
28.12
28.47
u/ml
0.04
294
2894
34
329
1.03
0.03
1.8
2.1
77.24
76.54
%
0.15
34
320
16
151
1.06
0.03
1.6
1.9
—
—
—
0
0
273
2748
0.99
0.03
2.0
2.3
10.74
10.50
g/l
0.51
243
2544
13
138
0.94
0.02
1.0
1.1
—
—
—
0
0
16
168
0.95
0.02
2.8
1.7
2.62
2.66
mg/l
0.04
16
161
35
341
1.03
0.02
1.3
1.2
—
—
—
0
0
202
2007
1.01
0.02
1.4
1.5
0.67
0.56
nmol/l
0.38
173
1684
24
232
1.03
0.02
1.0
1.2
—
—
—
0
0
374
3755
1.00
0.02
1.3
1.4
—
—
—
0
0
164
1651
0.99
0.01
3.2
3.4
40.84
34.48
ug/l
0.06
106
1090
446
4474
1.00
0.01
1.7
1.6
—
—
—
0
0
22
213
1.03
0.01
3.6
2.2
31.41
32.10
pg
0.27
22
213
60
608
0.99
0.01
2.0
2.3
—
—
—
0
0
55
543
1.01
0.01
1.5
2.1
—
—
—
0
0
16
154
1.04
0.00
1.1
1.1
—
—
—
0
0
39
384
1.02
0.00
1.4
1.6
40.24
39.92
g/l
0.15
33
358
46
454
1.01
0.00
1.9
1.7
10.09
10.40
g/l
0.24
41
427
47
476
0.99
0.00
1.1
1.0
0.67
0.37
u/ml
—
10
108
832
8327
1.00
0.00
1.3
1.3
7.76
7.34
u/ml
0.09
326
3634
14
138
1.01
0.00
1.0
1.1
3.81
4.64
mg/g
1.41
14
133
15
148
1.01
0.00
2.8
2.5
10.45
11.06
%
0.28
15
148
19
188
1.01
0.00
1.1
1.3
132.11
145.03
mmol/24h
0.63
19
188
10
95
1.05
0.00
1.7
2.2
—
—
—
0
0
205
2052
1.00
0.00
2.3
2.0
0.23
0.23
g/l
0.59
194
1936
10
96
1.04
0.00
1.0
1.1
—
—
—
0
0
21
206
1.02
0.00
1.3
2.0
17.02
169.59
ug/l
0.89
21
197
55
547
1.01
0.00
4.4
3.8
121.41
102.54
u/ml
0.10
25
185
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
347.14
—
0
7
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
4.21
—
0
8
0
7
0.00
0.00
0.0
1.7
—
104.23
—
0
7
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
6
59
1.02
-0.00
1.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
7.96
—
0
9
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
6
65
0.92
-0.00
11.7
6.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
11
110
1.00
-0.00
3.6
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
9.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
617.60
—
0
5
7
73
0.96
-0.00
1.1
1.6
—
—
—
0
0
8
86
0.93
-0.00
1.6
1.5
32.27
37.13
g/l
—
8
81
6
59
1.02
-0.00
1.0
1.5
—
126.98
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
69.20
—
0
5
7
76
0.92
-0.00
1.3
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
3.4
2.0
20.60
24.74
mg/l
—
5
53
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint O15_POSTPART_HAEMORRH_ANATOMY and mortality.

Females

Parameter HR [95% CI] p-value
O15_POSTPART_HAEMORRH_ANATOMY 0.525 [0.4, 0.68] < 0.001
Birth year 0.996 [0.99, 1.0] 0.323

During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 21640 females with O15_POSTPART_HAEMORRH_ANATOMY died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_POSTPART_HAEMORRH_ANATOMY.

N-year risk Females Males
1 0.046% No data
5 0.315% No data
10 0.742% No data
15 1.405% No data
20 2.702% No data

Relationships between endpoints

Index endpoint: O15_POSTPART_HAEMORRH_ANATOMY – Postpartum haemorrhage due to anatomy

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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