Postpartum haemorrhage due to anatomy

O15_POSTPART_HAEMORRH_ANATOMY

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O72.1
  • Hospital discharge: ICD-9 6661
  • Cause of death: ICD-10 O72.1
  • Cause of death: ICD-9 6661

2 out of 7 registries used, show all original rules.

4590

4. Check minimum number of events

None

4590

5. Include endpoints

None

4590

6. Filter based on genotype QC (FinnGen only)

4590

Control definitions (FinnGen only)

Control exclude
!(NUMBER_OF_OFFSPRING>0), !(O15_DELIVERY, O15_DELIVERY_PROXY)

Extra metadata

First used in FinnGen datafreeze
DF8

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 29763 29763 -
Only index persons 29492 29492 -
Unadjusted period prevalence (%)
Whole population 0.85 0.85 -
Only index persons 1.08 1.08 -
Median age at first event (years)
Whole population - 30.31 -
Only index persons - 30.30 -

-FinnGen-

Key figures

All Female Male
Number of individuals 4590 4590 -
Unadjusted period prevalence (%) 1.56 1.56 -
Median age at first event (years) 30.62 30.62 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
4108
Matched controls
41080
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
6661A
ICD-9 Finland
Postpartum haemorrhage, Other immediate postpartum haemorrhage[HAEMORRHAGIA POST PARTUM ATONICA UTERI]
+∞
323.0
424
*
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
4503599627370496.0
323.0
3536
12
O80.8
ICD-10 Finland
Other single spontaneous delivery
3.7
211.8
1127
3825
6661X
ICD-9 Finland
Postpartum haemorrhage, Other immediate postpartum haemorrhage[HAEMORRHAGIA POST PARTUM ACUTA ALIA]
+∞
163.6
156
*
O72.0
ICD-10 Finland
Third-stage haemorrhage
3.9
106.1
478
1339
MBA04
NOMESCO Finland
Curettage of uterus after delivery
7.1
84.1
214
314
SPAT1375
SPAT
Structural ultrasound screening, weeks 18+0-21+6
3.7
60.3
284
814
O70.1
ICD-10 Finland
Second degree perineal laceration during delivery
2.5
54.9
457
1923
WW500
NOMESCO Finland
Blood transfusion
4.0
53.5
229
604
SPAT1373
SPAT
Combined screening in early pregnancy
2.6
49.3
378
1513
MAX99
NOMESCO Finland
Assistance to normal delivery
1.7
47.6
1408
9705
Z39.2
ICD-10 Finland
Routine postpartum follow-up
1.5
37.5
1977
15489
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
2.8
36.7
257
971
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
1.5
33.1
1822
14259
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
2.6
32.0
242
958
SPAT1197
SPAT
Extensive health check-up of expecting family
1.5
29.6
2010
16292
Z10.8
ICD-10 Finland
Routine general health check-up of other defined subpopulations
2.3
29.4
282
1267
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
2.2
27.5
282
1306
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
2.4
27.1
245
1069
W92
ICPC
Compl labour/ delivery livebirth
2.0
26.5
345
1772
MBC30
NOMESCO Finland
Repair of partial rupture of perineum
2.2
25.0
281
1356
SPAT1380
SPAT
Postpartum check-up
1.4
24.2
1554
12284
W78
ICPC
Pregnancy
1.4
23.5
2158
18176
SPAT1200
SPAT
Guidance for breast-feeding and breast care
1.8
23.2
429
2501
W85
ICPC
Gestational diabetes
1.7
22.8
576
3687
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
2.1
21.9
257
1263
SPAT1195
SPAT
Antenatal classes
1.7
21.8
469
2863
MBC00
NOMESCO Finland
Repair of obstetric laceration of cervix uteri
7.5
20.4
48
65
O61.8
ICD-10 Finland
Other failed induction of labour
4.5
19.5
69
155
O71.3
ICD-10 Finland
Obstetric laceration of cervix
7.1
19.3
47
67
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
2.1
19.2
221
1078
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
1.7
17.9
416
2588
SPAT1246
SPAT
Screening of depression or other psychiatric problem
1.6
17.9
486
3157
SPAT1379
SPAT
Health check-up of pregnant person
1.3
17.8
1722
14361
8831
FHL
Uterine exploration and / or scraping or suction emptying (ad 24 hours)
6.0
16.9
46
77
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
1.4
16.7
1167
9215
MBB10
NOMESCO Finland
Packing of delivered uterus
9.8
16.6
33
34
W90
ICPC
Uncompl labour/delivery livebirth
1.5
15.9
675
4851
O73.1
ICD-10 Finland
Retained portions of placenta and membranes, without haemorrhage
2.8
15.0
97
353
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
1.4
14.3
954
7440
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.3
13.8
1106
8871
SPAT1189
SPAT
Other ultrasound examination during pregnancy
1.5
13.8
444
3001
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
1.3
13.8
1626
13786
MBC33
NOMESCO Finland
Repair of complete rupture of perineum
2.6
13.3
93
357
Z34
ICD-10 Finland
Supervision of normal pregnancy
1.4
12.9
601
4391
6653B
ICD-9 Finland
Other obstetrical trauma, Laceration of cervix
15.4
12.6
20
13
O48
ICD-10 Finland
Prolonged pregnancy
1.5
12.5
383
2559
Z71.8
ICD-10 Finland
Other specified counselling
0.7
11.9
668
8567
8834
FHL
Kerviksrupure repair
17.1
11.2
17
10
O41.8
ICD-10 Finland
Other specified disorders of amniotic fluid and membranes
3.1
10.9
57
183
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
0.4
10.7
47
1123
W29
ICPC
Pregnancy symptom/complaint other
1.5
10.3
346
2360
MAE00
NOMESCO Finland
Outlet vacuum delivery
1.4
10.3
560
4195
O81.4
ICD-10 Finland
Vacuum extractor delivery
1.4
10.3
641
4917
N81.6
ICD-10 Finland
Rectocele
1.8
10.3
174
989
SPAT1324
SPAT
Screening procedure
0.8
10.2
799
9824
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
1.6
10.2
284
1852
Z39.1
ICD-10 Finland
Care and examination of lactating mother
1.6
10.2
251
1587
WX600
NOMESCO Finland
Single shot through catheter
1.8
10.2
178
1019
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
2.0
9.8
127
657
O62.3
ICD-10 Finland
Precipitate labour
4.5
9.5
32
71
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
0.4
9.4
42
998
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
0.3
9.3
25
727
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
2.4
9.1
72
298
PC7NT
NOMESCO Finland
Endovascular occlusion of uteral arteries to stop puerperal bleeding
8.3
9.0
19
23
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.2
8.7
2619
24214
SPAT1190
SPAT
Insertion or removal of intrauterine contraceptive device
1.3
8.6
601
4685
103
Kela drug reimbursment
Diabetes, insulin-treated
0.6
8.6
146
2328
O70.22
ICD-10 Finland
III degree perineal tear involving one half or more of external anal sphincter thickness torn during childbirth
3.6
8.5
36
100
WX234
NOMESCO Finland
Paracervical blockade
0.6
8.5
140
2244
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
1.6
8.4
201
1263
215
Kela drug reimbursment
Diabetes, non-insulin-treated
0.6
8.4
146
2318
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.8
8.3
135
758
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
1.4
8.3
333
2358
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
0.4
7.9
27
709
MBA05
NOMESCO Finland
Curettage of uterus after abortion
1.9
7.8
107
566
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
0.6
7.5
166
2500
O47.9
ICD-10 Finland
False labour, unspecified
1.6
7.5
196
1263
A10AA02
ATC
NA
0.3
7.4
18
548
WX725
NOMESCO Finland
Noninvasive ventilation
0.4
7.4
29
721
N81.1
ICD-10 Finland
Cystocele
1.7
7.4
135
788
K05.31
ICD-10 Finland
Periodontitis pronounced
0.5
7.3
43
923
A10AE05
ATC
insulin detemir; parenteral
0.4
7.2
34
789
SPAT1128
SPAT
Instruction of pelvic floor / sphincter exercises
1.9
7.2
94
490
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
1.8
7.2
112
623
A10AA01
ATC
NA
0.3
7.2
18
537
H04AA01
ATC
glucagon; nasal, parenteral
0.4
7.1
26
662
A10AE04
ATC
insulin glargine; parenteral
0.5
7.1
56
1092
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.2
7.1
1165
10072
RD211
NOMESCO Finland
NA
0.4
7.0
35
792
H01CC01
ATC
ganirelix; parenteral
1.5
6.9
205
1363
O99.80
ICD-10 Finland
The fear of childbirth
1.3
6.8
559
4451
B01AB05
ATC
enoxaparin; parenteral
1.3
6.7
740
6115
W31
ICPC
Pregnancy, Medical examin/health eval partial
0.5
6.7
39
838
W05
ICPC
Pregnancy vomiting/nausea
1.7
6.6
120
702
XMA22
NOMESCO Finland
General examination of pregnant woman
0.7
6.6
341
4453
EBA00
NOMESCO Finland
Extraction of tooth
0.8
6.6
890
10380
WX720
NOMESCO Finland
Own respiration
0.4
6.5
20
545
D82
ICPC
Teeth/gum disease
1.2
6.5
1493
13301
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
0.5
6.5
57
1074
TLW12
NOMESCO Finland
Insertion of frozen embryo
1.6
6.5
139
854
MBW96
NOMESCO Finland
Other operation after delivery or abortion
3.5
6.5
28
81
O41.9
ICD-10 Finland
Disorder of amniotic fluid and membranes, unspecified
2.5
6.5
46
183
MCA30
NOMESCO Finland
Supravaginal caesarean hysterectomy
14.3
6.4
10
7
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.2
6.3
896
7613
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
0.3
6.3
16
475
6661B
ICD-9 Finland
NA
+∞
6.2
6
*
O63.1
ICD-10 Finland
Prolonged second stage (of labour)
1.4
6.2
279
2024
ZXA00
NOMESCO Finland
Right side
0.7
6.1
277
3687
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.2
6.1
1758
15947
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.5
6.1
214
1480
WZB00
NOMESCO Finland
Telephone receipt or other advice
0.8
6.0
959
11030

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
477
2184
2.32
58.67
2.3
2.9
—
—
—
0
0
1484
10089
1.70
56.12
1.8
1.7
—
—
—
0
0
337
1348
2.62
55.51
1.7
2.2
3.6
3.7
g/l
1.55
312
1265
1887
13966
1.60
49.18
1.8
1.8
—
—
—
0
0
1117
7401
1.67
44.69
1.5
1.5
—
—
—
0
0
3237
36439
0.62
43.44
10.4
11.1
332.6
332.7
g/l
0.03
3214
36185
3278
36044
0.68
27.65
10.3
10.5
13.4
13.3
%
1.46
3229
35483
1325
10035
1.45
26.54
2.5
2.2
—
—
—
0
0
257
1273
2.08
25.54
1.5
1.5
—
—
—
0
0
1247
9489
1.43
23.86
1.7
1.5
—
—
—
0
0
77
221
3.53
22.75
1.2
1.2
—
—
—
0
0
864
6311
1.45
20.12
2.3
2.2
—
—
—
0
0
2301
19774
1.33
19.31
2.4
2.0
—
—
—
0
0
2115
18120
1.31
17.42
1.8
1.7
—
—
—
0
0
2632
23311
1.30
16.56
4.7
4.1
—
—
—
0
0
99
399
2.51
16.12
1.7
1.6
4.9
5.5
mmol/l
6.99
94
360
47
125
3.79
15.62
1.0
1.0
—
—
—
0
0
2265
19790
1.29
15.26
1.9
1.8
—
—
—
0
0
530
3761
1.46
14.00
1.6
2.0
28.3
28.8
s
1.36
511
3627
755
9772
0.73
13.79
3.4
3.2
—
—
—
0
0
2368
21115
1.25
12.29
2.1
2.0
—
—
—
0
0
1816
20663
0.80
11.82
2.3
2.3
—
—
—
0
0
1099
9065
1.28
10.79
3.7
3.7
1.1
1.0
inr
1.00
395
3480
243
1550
1.60
10.53
1.3
1.4
17.3
19.9
u/l
0.72
200
1300
1022
12167
0.79
9.30
2.3
2.7
26.0
27.7
u/l
1.11
979
11659
878
7267
1.26
8.10
2.4
2.3
7992.6
7612.6
u/l
0.13
451
3444
782
9474
0.79
8.09
3.3
3.3
1.0
1.0
kg/l
0.07
170
1590
92
481
1.93
8.07
1.5
1.4
—
—
—
0
0
53
223
2.39
8.06
1.2
1.1
15.9
11.6
u/ml
0.20
11
47
1820
16257
1.20
7.89
1.9
1.9
—
—
—
0
0
2017
22168
0.84
7.70
3.1
3.1
0.0
0.0
estimate
0.38
455
4983
84
435
1.95
7.60
3.8
3.4
31.6
26.3
mu/l
0.56
84
416
316
4257
0.72
7.06
2.4
2.3
200.2
253.2
ng/l
0.17
137
1625
597
7343
0.79
6.90
3.1
3.0
7.4
7.4
ph
0.57
146
1534
2033
22207
0.85
6.87
4.2
4.3
0.0
0.0
estimate
1.34
483
5170
49
219
2.25
6.57
2.6
2.7
—
26.4
—
0
5
2058
22377
0.85
6.34
3.2
3.2
0.0
0.0
estimate
1.57
484
5111
112
672
1.68
6.32
1.3
1.4
—
—
—
0
0
18
47
3.84
6.25
1.3
1.4
—
—
—
0
0
1136
12945
0.84
6.14
2.8
3.0
62.0
62.0
e6/l
0.00
716
8027
4350
42606
1.40
6.02
9.8
8.8
—
—
—
0
0
115
714
1.63
5.73
1.6
2.3
—
—
—
0
0
1049
9128
1.19
5.71
2.0
2.0
2.8
2.5
mg/l
3.50
894
7897
214
1526
1.42
5.57
1.8
1.8
21.0
20.5
s
0.40
180
1214
44
203
2.18
5.52
1.1
1.1
10.3
5.6
u/ml
—
10
34
93
1513
0.61
5.44
4.2
2.9
1.4
1.6
mmol/l
0.16
78
1190
570
4691
1.25
5.42
1.2
1.2
—
—
—
0
0
16
43
3.73
5.36
1.3
1.2
—
—
—
0
0
59
311
1.91
5.19
1.5
1.4
—
—
—
0
0
132
869
1.53
5.16
1.2
1.3
1.2
1.3
nmol/l
0.42
114
733
283
3683
0.75
5.03
1.4
1.3
—
—
—
0
0
101
1575
0.63
4.96
4.0
2.8
—
7.4
—
0
8
638
7509
0.83
4.76
1.4
1.5
1.3
1.3
mmol/l
0.49
535
6624
16
47
3.41
4.74
1.3
1.2
—
—
—
0
0
105
671
1.58
4.71
1.6
2.2
24.0
24.4
mmol/l
1.27
99
628
1574
17145
0.88
4.34
7.5
7.1
0.0
0.0
e9/l
1.37
1340
14405
401
4897
0.80
4.29
2.2
2.2
1.1
1.1
e6/l
0.05
226
2667
83
1276
0.64
3.89
1.1
1.2
—
—
—
0
0
69
1090
0.63
3.68
8.0
6.3
—
—
—
0
0
157
1148
1.38
3.66
1.3
1.3
2.9
6.8
u/ml
0.68
20
117
1213
11008
1.14
3.61
3.7
4.0
1.2
1.2
mmol/l
1.02
1082
10105
301
3721
0.80
3.61
1.2
1.2
—
—
—
0
0
880
9851
0.87
3.49
2.4
2.6
32.7
76.1
e6/l
1.62
649
7272
48
816
0.58
3.47
5.8
2.9
24.1
24.0
mmol/l
0.08
43
712
529
4536
1.19
3.34
3.0
3.1
—
—
—
0
0
1483
16004
0.89
3.26
4.1
4.4
8.9
9.3
umol/l
1.46
1393
14971
341
2816
1.23
3.20
1.8
1.8
3.9
4.2
e9/l
1.94
258
2461
157
1175
1.35
3.20
1.3
1.3
5.6
8.9
u/ml
0.51
29
187
737
8301
0.87
3.17
4.4
5.1
—
—
—
0
0
46
267
1.73
3.11
2.0
2.1
—
—
—
0
0
470
5474
0.84
3.10
3.8
4.1
15.5
14.2
mg/mmol
0.23
309
3699
368
3075
1.21
3.09
2.0
2.2
5.0
4.7
umol/l
0.34
238
2252
451
5264
0.84
3.05
3.1
3.4
670.7
502.0
mg/l
0.24
306
3497
231
2882
0.79
3.04
2.4
2.1
32.4
35.4
u/l
0.58
200
2475
23
106
2.18
3.02
1.1
1.0
4.6
1.0
u/ml
0.44
16
68
71
1057
0.67
2.94
3.1
2.1
138.5
55.7
ng/l
0.86
63
922
641
7248
0.87
2.90
3.0
3.2
7.7
7.9
mmol/l
0.37
572
6392
999
9070
1.13
2.89
2.1
2.1
12.3
21.5
ng/l
2.51
300
2754
48
291
1.66
2.81
2.0
2.1
—
—
—
0
0
8
217
0.37
2.64
1.3
1.4
4.2
4.9
u/l
—
8
183
796
8815
0.88
2.63
2.4
2.5
0.2
0.2
e6/l
0.05
575
6422
2391
24983
0.91
2.59
5.8
5.8
68.7
69.3
u/l
0.51
2216
23560
1188
10972
1.11
2.53
5.1
5.1
—
—
—
0
0
76
1076
0.70
2.46
1.3
1.3
152.4
103.9
u/ml
0.42
20
294
132
1006
1.32
2.46
2.5
2.3
1.1
1.1
g/l
0.08
118
896
306
3621
0.83
2.45
1.9
2.2
5.7
5.6
umol/l
0.04
252
3019
148
1149
1.30
2.42
2.7
2.7
—
—
—
0
0
54
351
1.54
2.42
1.1
1.2
2.8
25.2
u/ml
—
6
34
813
8946
0.89
2.41
2.3
2.4
—
—
—
0
0
1138
12282
0.90
2.37
3.3
3.3
0.0
0.0
estimate
0.65
473
5113
362
4206
0.85
2.36
2.1
2.1
2.4
2.4
mmol/l
0.01
309
3619
406
4668
0.86
2.32
2.1
2.3
4.9
5.0
e6/l
0.09
228
2451
728
8043
0.89
2.31
1.6
1.6
—
—
—
0
0
189
2322
0.81
2.24
2.6
3.0
—
—
—
0
0
1132
12185
0.91
2.22
2.1
2.2
—
—
—
0
0
151
1197
1.27
2.14
1.1
1.1
0.9
1.3
u/ml
0.82
31
303
3112
30230
1.09
2.07
4.2
4.0
1474.7
1127.0
e6/l
0.10
28
312
271
3185
0.84
2.05
1.9
2.0
—
—
—
0
0
1085
11656
0.91
2.02
3.6
3.8
37.2
37.1
g/l
0.31
1005
10896
111
1431
0.77
2.01
9.1
6.3
—
—
—
0
0
141
1120
1.27
1.99
1.6
2.3
7.4
7.4
ph
0.56
13
169
319
2750
1.17
1.98
1.3
1.3
40.6
29.3
au/ml
—
8
102
109
1402
0.77
1.94
3.9
2.7
—
—
—
0
0
4511
44838
1.35
1.93
14.2
13.5
29.9
29.9
pg
0.41
4482
44586
4512
44850
1.35
1.93
14.3
13.6
7.2
6.9
e9/l
13.05
4459
44144
4511
44839
1.35
1.92
14.2
13.5
89.7
89.8
fl
0.57
4482
44588
142
1134
1.26
1.92
1.6
2.3
4.9
5.0
kpa
1.39
131
1050
15
295
0.51
1.92
1.3
1.5
—
—
—
0
0
15
295
0.51
1.92
1.3
1.5
—
—
—
0
0
15
295
0.51
1.92
1.3
1.5
—
—
—
0
0
15
295
0.51
1.92
1.3
1.5
—
—
—
0
0
163
1323
1.24
1.92
1.3
1.3
23.2
28.1
u/ml
—
8
99
129
1621
0.79
1.91
2.4
2.5
—
—
—
0
0
111
1420
0.78
1.90
1.6
1.8
—
—
—
0
0
918
9907
0.91
1.87
3.5
3.6
—
—
—
0
0
4511
44844
1.34
1.87
14.2
13.6
4.4
4.4
e12/l
21.75
4456
44180
92
1199
0.76
1.83
1.3
1.1
—
—
—
0
0
87
1141
0.76
1.82
1.3
1.3
—
—
—
0
0
858
9268
0.91
1.78
2.2
2.6
2.3
2.3
mmol/l
0.26
756
8458
263
2254
1.18
1.78
1.7
1.6
7.4
7.4
mmol/l
0.12
178
1365
4512
44865
1.33
1.78
14.3
13.6
130.4
132.3
g/l
24.02
4484
44604
3137
30567
1.08
1.76
4.0
4.0
—
—
—
0
0
4506
44802
1.31
1.73
14.3
13.6
254.3
265.9
e9/l
34.33
4454
44153
109
858
1.28
1.70
1.1
1.1
0.1
0.3
u/ml
0.55
15
169
0
48
0.00
1.69
0.0
1.4
—
50.5
—
0
29
23
133
1.73
1.69
1.7
2.3
—
—
—
0
0
8
31
2.58
1.66
1.1
2.0
—
—
—
0
0
144
1176
1.23
1.65
1.1
1.1
2.3
1.0
u/ml
0.39
55
467
80
1043
0.76
1.63
3.5
4.6
—
—
—
0
0
61
827
0.73
1.63
1.9
2.3
—
—
—
0
0
639
6968
0.90
1.61
2.0
2.2
8.2
9.3
e6/l
0.84
546
5930
132
1072
1.24
1.60
1.3
1.2
—
—
—
0
0
376
3343
1.14
1.57
1.2
1.3
204.2
157.1
u/ml
0.54
354
3106
829
7698
1.09
1.56
2.0
2.0
2780.3
1349.6
umol/l
0.63
738
6962
17
92
1.85
1.55
5.7
2.4
109.6
4156.3
mg/l
0.79
11
67
95
746
1.28
1.54
4.1
3.2
—
—
—
0
0
18
310
0.58
1.53
2.9
2.0
5.6
6.9
mmol/l
2.25
18
301
978
9162
1.09
1.50
1.8
1.7
1.1
0.9
mg/l
1.50
741
6745
5
128
0.39
1.48
18.8
14.0
1209.8
1220.1
nmol/l
—
5
118
422
3802
1.12
1.44
1.6
1.6
1085.6
1212.9
nmol/l
1.99
335
3078
76
977
0.77
1.43
1.1
1.2
259.0
247.9
u/ml
0.14
45
695
333
2962
1.13
1.41
2.3
2.3
30.7
22.1
au/ml
0.38
19
247
126
1035
1.22
1.41
1.3
1.3
—
—
—
0
0
212
2447
0.86
1.37
3.8
3.7
0.6
0.6
%
0.02
28
370
5
124
0.40
1.36
18.0
10.3
780.4
682.2
nmol/l
—
5
117
18
298
0.60
1.35
9.5
11.2
0.6
0.6
mmol/l
0.78
18
274
118
1430
0.82
1.34
5.0
6.1
6.0
6.1
mmol/l
0.09
111
1385
16
90
1.78
1.32
1.1
1.1
—
—
—
0
0
92
736
1.26
1.32
3.3
3.5
58.2
57.7
%
0.20
92
736
285
3210
0.88
1.31
2.3
2.0
—
—
—
0
0
459
4182
1.11
1.30
1.2
1.1
—
—
—
0
0
24
153
1.57
1.28
1.3
1.4
—
—
—
0
0
9
175
0.51
1.28
1.9
2.0
24.1
28.3
%
—
9
170
39
542
0.72
1.27
2.9
3.6
29.4
22.5
u/ml
0.41
39
522
233
2654
0.87
1.27
4.0
3.8
1.4
0.9
%
0.59
38
511
288
3230
0.88
1.25
2.3
2.1
—
—
—
0
0
8
36
2.22
1.24
1.1
1.1
—
—
—
0
0
50
664
0.75
1.23
1.1
1.1
—
—
—
0
0
74
933
0.79
1.23
1.2
1.3
17.6
21.6
e6/l
0.14
58
728
256
2263
1.14
1.23
1.2
1.2
9.9
10.2
u/l
0.17
224
1959
74
932
0.79
1.22
1.2
1.4
242.9
1588.1
e6/l
1.16
60
775
10
189
0.53
1.22
2.3
2.1
6.8
8.2
%
—
10
183
288
3221
0.89
1.20
2.3
2.0
—
—
—
0
0
130
1093
1.19
1.19
1.9
2.8
0.4
0.3
g/l
0.37
54
471
9
171
0.53
1.17
1.0
1.7
—
—
—
0
0
18
286
0.63
1.17
1.7
2.9
—
—
—
0
0
96
786
1.23
1.15
1.4
1.3
—
—
—
0
0
31
439
0.70
1.15
1.3
1.4
—
—
—
0
0
83
669
1.25
1.15
1.2
1.4
—
2.1
—
0
14
36
496
0.72
1.14
1.4
2.5
25.1
23.7
mmol/l
3.35
31
439
39
530
0.73
1.14
2.8
2.8
—
—
—
0
0
165
1423
1.17
1.13
1.2
1.1
2.7
1.3
u/ml
0.53
68
514
217
2458
0.88
1.12
4.0
3.9
0.1
0.2
%
0.36
32
391
262
2932
0.89
1.12
2.4
2.1
—
—
—
0
0
38
276
1.38
1.11
1.1
1.4
4.2
6.4
ug/l
2.36
30
245
7
31
2.26
1.10
1.0
1.1
1.1
1.3
umol/24h
—
7
31
227
2559
0.88
1.09
3.9
3.8
0.3
0.2
%
0.34
35
472
989
10409
0.94
1.08
2.2
2.2
53.7
55.9
u/l
0.85
908
9747
17
267
0.64
1.07
1.1
1.6
1.8
1.2
promille
—
10
200
26
372
0.70
1.05
1.7
1.4
345.3
366.7
pmol/l
0.10
19
292
100
833
1.20
1.04
1.3
1.2
3.0
4.6
u/ml
1.19
40
327
87
1053
0.82
1.03
1.8
1.8
—
—
—
0
0
668
6266
1.08
1.02
1.3
1.4
580.4
607.8
titre
0.12
137
1221
149
1289
1.16
1.01
1.1
1.2
—
—
—
0
0
21
309
0.68
0.99
1.6
1.4
—
—
—
0
0
11
61
1.81
0.98
1.1
1.1
—
—
—
0
0
11
61
1.81
0.98
1.1
1.1
—
—
—
0
0
11
61
1.81
0.98
1.1
1.1
—
—
—
0
0
30
413
0.72
0.98
1.3
1.2
—
—
—
0
0
74
904
0.82
0.98
8.1
7.5
—
—
—
0
0
38
284
1.34
0.96
1.6
1.5
—
—
—
0
0
407
3752
1.09
0.96
1.3
1.3
—
—
—
0
0
0
32
0.00
0.95
0.0
1.0
—
—
—
0
0
225
2013
1.12
0.95
1.5
1.6
—
—
—
0
0
648
6092
1.07
0.95
2.8
3.1
—
—
—
0
0
124
1065
1.17
0.94
1.1
1.1
4.8
4.9
u/ml
0.01
46
412
178
2012
0.88
0.93
5.6
6.9
1.1
1.0
inr
0.71
40
422
25
351
0.71
0.93
6.8
2.6
—
—
—
0
0
372
4037
0.91
0.92
1.3
1.5
351.0
287.4
mu/l
0.33
315
3567
3511
35573
0.94
0.91
2.9
3.1
2.9
2.9
mmol/l
1.08
3291
33866
1314
12647
1.05
0.90
4.4
4.5
1.2
1.2
mmol/l
2.60
1101
10633
31
227
1.37
0.90
1.2
1.4
22.6
25.4
umol/l
0.22
26
219
24
337
0.71
0.90
2.5
1.9
1.2
1.2
mmol/l
0.41
24
324
48
608
0.79
0.89
2.5
3.5
1.4
1.3
mmol/l
0.12
48
601
258
2343
1.11
0.85
1.2
1.2
3.4
3.8
ug/l
0.69
236
2230
57
702
0.81
0.84
2.6
4.2
—
—
—
0
0
97
1135
0.85
0.84
1.6
1.7
5.7
4.2
ug/l
0.31
87
1004
117
1012
1.16
0.83
1.1
1.1
5.3
4.5
u/ml
0.16
45
413
144
1265
1.14
0.83
1.1
1.1
6.7
5.6
u/ml
0.36
67
663
2006
20577
0.96
0.83
6.1
6.7
3.9
4.0
e9/l
1.46
1777
18202
3347
33919
0.95
0.81
4.7
4.5
14.2
14.1
pmol/l
0.16
3113
32209
26
189
1.38
0.80
1.6
2.6
—
—
—
0
0
97
1129
0.86
0.79
1.4
1.4
29.5
31.0
nmol/l
0.26
82
1053
457
4881
0.93
0.79
1.4
1.5
—
—
—
0
0
168
1880
0.89
0.78
6.4
6.1
-0.2
0.5
mmol/l
1.21
114
1350
83
703
1.18
0.78
3.6
3.3
24.6
23.5
mg/l
0.10
41
431
98
842
1.17
0.78
1.1
1.1
2.5
10.2
au/ml
—
9
63
436
4076
1.08
0.77
1.2
1.2
—
—
—
0
0
2557
25081
1.04
0.77
3.1
3.1
57.9
55.3
ug/l
0.53
2376
23930
191
2118
0.90
0.76
2.8
2.8
1.2
1.2
mmol/l
0.18
161
1834
600
6332
0.94
0.74
2.1
2.3
531.9
533.7
mosm/kgh2o
0.06
499
5309
51
414
1.23
0.74
1.5
1.6
—
—
—
0
0
138
1552
0.89
0.72
7.4
5.3
1.4
1.2
mmol/l
0.59
131
1498
670
6374
1.06
0.71
2.8
2.5
109.5
95.5
ug/g
0.63
500
4977
2901
29459
0.96
0.71
3.2
3.5
35.8
36.4
mmol/mol
4.11
2734
28104
34
264
1.29
0.71
1.6
1.3
9.5
9.1
umol/l
0.27
34
253
57
472
1.21
0.70
1.2
1.1
1.0
1.0
ratio
0.02
17
171
28
365
0.77
0.69
1.2
3.7
5.8
6.3
mmol/l
0.90
23
285
32
409
0.78
0.68
1.0
1.1
—
—
—
0
0
5
27
1.85
0.68
1.0
1.1
—
—
—
0
0
35
275
1.27
0.68
1.1
1.1
294.7
296.8
mg/l
0.07
28
257
4037
40070
1.06
0.67
8.6
8.9
17.9
17.6
mg/l
0.25
3225
31212
1299
13396
0.96
0.67
2.6
2.7
—
—
—
0
0
7
43
1.63
0.66
1.0
1.4
48.1
80.9
mu/l
—
7
34
16
226
0.71
0.66
5.9
3.0
—
—
—
0
0
5
94
0.53
0.66
2.0
1.5
—
—
—
0
0
83
716
1.16
0.66
1.4
1.4
—
—
—
0
0
16
111
1.44
0.65
1.1
1.2
0.0
3.7
u/ml
—
5
17
169
1866
0.90
0.65
6.4
6.1
15.1
14.4
kpa
0.51
163
1788
169
1866
0.90
0.65
6.4
6.1
4.8
4.9
kpa
0.36
164
1787
437
4117
1.07
0.65
1.9
2.0
2.5
2.5
g/l
0.20
394
3793
15
103
1.46
0.65
1.0
1.2
—
—
—
0
0
29
371
0.78
0.64
1.9
1.2
—
—
—
0
0
229
2487
0.92
0.63
2.6
2.2
—
—
—
0
0
38
305
1.25
0.63
1.1
1.4
874.3
468.1
mu/l
0.39
38
292
48
396
1.21
0.63
1.0
1.0
—
—
—
0
0
14
200
0.70
0.62
1.8
2.6
—
—
—
0
0
368
3454
1.07
0.62
1.4
1.3
—
—
—
0
0
39
315
1.24
0.62
1.1
1.4
71.8
72.3
%
0.06
39
302
15
211
0.71
0.62
1.7
1.6
35.6
46.0
%
—
8
120
788
7567
1.05
0.61
2.5
2.8
99.9
99.7
%
0.11
762
7313
205
1881
1.09
0.61
1.4
1.3
—
—
—
0
0
34
423
0.80
0.60
1.8
1.2
—
0.1
nmol/l
—
0
6
2688
27269
0.97
0.57
3.5
3.4
8.5
8.4
mm/h
0.25
2474
25826
82
935
0.87
0.56
1.1
1.1
—
—
—
0
0
12
82
1.46
0.54
1.0
1.0
—
—
—
0
0
97
1088
0.89
0.53
1.6
1.6
8.0
11.0
mmol/l
1.00
11
55
6
39
1.54
0.53
1.3
1.2
70.0
83.0
ng/l
—
6
39
33
404
0.82
0.53
1.1
1.5
—
—
—
0
0
31
382
0.81
0.52
1.9
1.2
—
—
nmol/l
—
0
0
141
1284
1.10
0.51
1.9
2.1
68.0
67.7
g/l
0.22
131
1204
44
522
0.84
0.51
2.1
3.8
3.7
3.7
mmol/l
0.20
44
487
3504
35351
0.96
0.51
2.8
3.0
4.7
4.8
mmol/l
1.35
3311
33932
96
856
1.12
0.51
1.2
1.1
—
—
—
0
0
61
529
1.16
0.49
1.6
2.0
159.2
200.6
ug/l
0.26
48
443
67
586
1.15
0.48
2.3
2.3
—
—
—
0
0
16
212
0.75
0.48
1.1
1.2
—
—
—
0
0
7
108
0.65
0.48
1.0
1.1
—
—
—
0
0
53
614
0.86
0.48
1.5
2.1
131.7
131.5
g/l
0.03
33
504
1149
11795
0.97
0.48
1.3
1.3
1.3
1.5
u/ml
0.24
311
3638
36
431
0.83
0.47
1.2
1.3
—
—
—
0
0
7
47
1.49
0.47
1.0
1.1
—
—
—
0
0
43
364
1.18
0.47
1.3
1.2
—
—
—
0
0
1041
10701
0.96
0.47
1.7
1.6
100.0
99.8
pmol/l
0.06
614
6090
36
430
0.84
0.47
1.1
1.3
0.4
0.4
g/l
0.28
27
298
36
430
0.84
0.47
1.1
1.3
3.1
3.1
g/l
0.01
25
296
3489
35180
0.97
0.46
2.8
2.9
1.5
1.5
mmol/l
1.87
3297
33747
62
707
0.88
0.46
1.2
1.2
292.4
343.1
ug/g
0.94
24
318
382
3637
1.05
0.45
3.7
3.5
4.5
4.6
pmol/l
1.30
335
3324
1793
17606
1.03
0.45
4.7
4.8
56.6
56.6
%
0.01
1659
16610
353
3710
0.95
0.44
1.9
1.9
387.3
378.2
nmol/l
0.46
331
3445
1816
17846
1.03
0.43
4.9
4.9
30.2
30.0
%
0.60
1675
16785
5
31
1.61
0.43
2.2
3.2
—
—
—
0
0
14
185
0.76
0.43
1.5
1.7
—
—
—
0
0
3612
36381
0.97
0.43
6.8
7.4
3.9
3.9
mmol/l
0.37
3454
35293
544
5652
0.96
0.43
1.5
1.4
21.0
20.9
nmol/l
0.10
474
5100
388
4063
0.95
0.42
1.5
1.7
—
—
—
0
0
136
1475
0.92
0.42
1.7
1.6
6.4
6.3
mmol/l
0.13
86
1045
5
33
1.52
0.41
1.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.6
—
168.2
—
0
15
0
16
0.00
0.41
0.0
5.2
—
—
—
0
0
0
17
0.00
0.40
0.0
4.4
—
—
—
0
0
0
17
0.00
0.40
0.0
2.0
—
—
—
0
0
344
3608
0.95
0.40
1.3
1.3
—
—
—
0
0
3604
36291
0.97
0.40
6.8
7.4
139.3
139.4
mmol/l
1.33
3468
35305
188
2008
0.93
0.40
1.2
1.3
0.4
1.0
u/ml
—
6
157
114
1045
1.09
0.40
1.1
1.1
—
—
—
0
0
114
1045
1.09
0.40
1.1
1.1
—
—
—
0
0
110
1007
1.09
0.40
1.3
1.3
—
—
—
0
0
12
160
0.75
0.39
2.5
1.7
4.0
3.9
mmol/l
0.32
12
160
12
160
0.75
0.39
2.5
1.7
106.9
106.3
mmol/l
0.35
12
160
0
19
0.00
0.39
0.0
1.0
—
7.8
—
0
7
0
19
0.00
0.39
0.0
2.4
—
402.8
—
0
19
1735
17062
1.03
0.39
5.1
5.1
7.5
7.6
%
1.82
1608
16104
37
430
0.86
0.37
1.1
1.3
7.1
6.5
g/l
0.63
28
298
47
536
0.88
0.37
2.2
2.0
0.5
1.4
ug/l
1.60
40
480
24
289
0.83
0.36
1.0
1.1
—
—
—
0
0
26
217
1.20
0.35
1.2
1.8
1.4
2.9
u/field
1.57
14
122
216
2283
0.94
0.35
3.4
3.0
—
—
—
0
0
25
208
1.20
0.35
1.1
1.1
5.5
2.5
u/ml
0.36
13
112
24
199
1.21
0.35
1.2
1.2
—
—
—
0
0
12
156
0.77
0.34
2.5
1.7
—
—
—
0
0
20
163
1.23
0.34
1.5
1.6
893.4
19494.1
e6/l
—
9
116
1456
14810
0.98
0.34
2.2
2.1
75.1
73.2
nmol/l
2.05
1356
14015
262
2749
0.95
0.33
1.2
1.2
—
—
—
0
0
13
100
1.30
0.33
1.4
1.2
—
—
—
0
0
66
730
0.90
0.33
1.1
1.1
114.9
12822.3
iu/ml
0.63
31
209
1720
16945
1.02
0.33
4.9
4.9
2.7
2.7
%
0.08
1566
15832
12
155
0.77
0.33
1.8
1.6
119.3
121.3
nmol/l
0.06
12
155
36
312
1.16
0.33
1.9
2.0
—
—
—
0
0
6
87
0.69
0.33
1.2
1.5
—
—
—
0
0
161
1711
0.94
0.32
1.1
1.1
—
—
—
0
0
6
47
1.28
0.32
1.0
1.3
305.3
348.6
pmol/l
—
6
37
15
187
0.80
0.32
1.1
1.1
—
—
—
0
0
12
154
0.78
0.32
1.0
1.1
—
—
—
0
0
25
295
0.85
0.32
7.3
2.5
70.5
63.0
%
1.10
25
295
56
622
0.90
0.31
1.5
1.5
0.6
0.6
g/l
0.18
45
474
59
653
0.90
0.31
2.1
2.9
1.2
1.2
mg/l
0.25
54
629
480
4649
1.04
0.30
1.9
2.0
15.0
15.1
umol/l
0.10
432
4313
187
1772
1.06
0.30
1.6
1.7
—
—
—
0
0
218
2075
1.05
0.30
1.3
1.3
—
—
—
0
0
272
2840
0.96
0.30
1.1
1.1
98.7
214.5
titre
—
8
81
38
431
0.88
0.30
1.1
1.3
—
—
—
0
0
33
287
1.15
0.30
1.0
1.0
—
—
—
0
0
7
56
1.25
0.29
1.0
1.5
—
127.0
—
0
6
29
250
1.16
0.29
1.3
1.8
40.9
41.7
%
0.04
20
143
34
297
1.15
0.29
2.0
2.2
42.8
46.2
%
—
10
53
31
356
0.87
0.29
1.2
1.2
—
—
—
0
0
25
292
0.86
0.29
4.4
2.9
36.6
26.4
mg/l
0.27
17
236
578
5940
0.97
0.29
1.4
1.5
9665106.8
54452283.9
pmol/l
3.09
507
5245
30
260
1.15
0.28
1.0
1.0
—
—
—
0
0
142
1338
1.06
0.28
1.8
2.0
0.2
0.2
g/l
0.49
135
1270
36
317
1.14
0.28
1.0
1.0
—
—
—
0
0
10
129
0.77
0.28
3.6
3.2
54.8
42.8
umol/l
—
10
118
24
280
0.86
0.28
1.3
1.3
—
—
—
0
0
367
3547
1.04
0.27
1.9
2.1
24.7
24.6
%
0.03
319
3029
125
1175
1.07
0.27
1.1
1.1
—
—
—
0
0
525
5107
1.03
0.27
1.3
1.3
130.3
154.1
iu/ml
0.76
202
2083
9
121
0.74
0.27
2.0
3.2
—
—
—
0
0
47
423
1.11
0.27
1.0
1.1
1.4
1.4
g/l
0.72
38
393
41
366
1.12
0.26
1.5
1.9
—
—
—
0
0
146
1383
1.06
0.25
1.8
2.0
1.2
1.2
g/l
0.44
140
1315
9
73
1.23
0.25
1.1
1.5
—
6.1
—
0
5
46
508
0.90
0.25
1.0
1.2
29.1
35.4
mg/l
1.04
38
425
1858
18784
0.98
0.24
4.8
5.0
0.2
0.2
e9/l
1.06
1675
17054
13
159
0.82
0.24
1.1
1.2
—
—
—
0
0
2777
27569
1.02
0.24
2.5
2.5
27.4
29.3
u/l
1.24
2666
26568
430
4422
0.97
0.24
1.5
1.5
—
—
—
0
0
6
84
0.71
0.24
2.3
2.1
143.5
149.8
nmol/l
—
6
75
3750
37656
0.98
0.24
5.1
5.0
1.6
1.8
mu/l
1.25
3510
36090
860
8757
0.98
0.23
1.5
1.5
—
—
—
0
0
80
857
0.93
0.23
1.1
1.3
—
—
—
0
0
13
106
1.23
0.23
1.2
1.3
6.3
6.2
mmol/l
0.08
13
100
3338
33554
0.98
0.23
2.6
2.7
1.1
1.1
mmol/l
0.95
3160
32226
5
39
1.28
0.23
1.4
1.2
—
—
—
0
0
7
94
0.74
0.22
2.1
2.3
15.6
21.7
ug/l
—
7
94
172
1797
0.96
0.22
1.4
1.5
0.7
0.6
nmol/l
0.40
146
1503
353
3635
0.97
0.22
2.5
2.8
0.8
0.8
mmol/l
0.25
331
3434
45
493
0.91
0.22
1.0
1.1
178.5
192.4
mg/l
0.61
37
437
22
191
1.15
0.21
1.1
1.5
3.5
2.5
u/field
0.23
15
137
207
1991
1.04
0.21
2.3
2.4
1.7
1.6
%
0.09
182
1780
2041
20226
1.02
0.21
3.3
3.6
6.0
6.0
mmol/l
0.92
1601
17132
28
315
0.89
0.21
1.6
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.6
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
35
388
0.90
0.21
1.4
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
0.2
—
0
6
1781
17988
0.98
0.21
4.8
5.0
0.5
0.5
e9/l
2.16
1597
16060
41
450
0.91
0.21
1.3
1.8
17.8
17.3
%
0.46
16
207
5
43
1.16
0.21
1.0
1.1
—
—
—
0
0
706
7193
0.98
0.21
1.6
1.8
145.0
132.5
u/l
0.20
671
6856
57
527
1.08
0.21
2.0
2.3
2.5
2.0
mmol/l
0.43
21
287
525
5134
1.03
0.21
1.3
1.3
23.9
22.5
iu/l
0.46
482
4542
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
28
249
1.13
0.20
2.9
2.8
807.9
880.5
e6/l
0.30
19
115
179
1719
1.04
0.20
1.1
1.1
2.1
4.6
u/ml
1.80
28
278
0
14
0.00
0.20
0.0
1.0
—
0.0
—
0
5
0
14
0.00
0.20
0.0
1.1
—
109.6
—
0
14
0
14
0.00
0.20
0.0
1.0
—
0.1
—
0
6
1789
18062
0.98
0.20
4.8
5.0
0.0
0.0
e9/l
0.50
1593
16067
6
48
1.25
0.20
1.2
1.1
—
—
—
0
0
29
259
1.12
0.20
1.0
1.4
—
—
—
0
0
26
292
0.89
0.20
4.2
3.0
26.6
45.5
mg/l
0.61
17
236
936
9499
0.98
0.19
1.3
1.4
2.0
2.0
g/l
0.16
591
6175
116
1105
1.05
0.19
1.2
1.3
21.8
36.3
u/ml
—
9
104
169
1625
1.04
0.19
2.3
2.2
3.6
4.2
iu/l
0.50
69
709
313
3217
0.97
0.19
1.4
1.3
226.7
234.2
miu/ml
0.15
170
1645
1575
15597
1.01
0.18
2.0
2.0
—
—
—
0
0
108
1133
0.95
0.18
2.3
2.1
—
—
—
0
0
41
377
1.09
0.17
1.1
1.1
1216.4
1478.3
miu/ml
1.11
41
377
13
110
1.18
0.17
3.5
3.1
—
—
—
0
0
25
224
1.12
0.17
3.1
3.2
7.9
7.7
mg/l
0.08
15
174
5
66
0.76
0.17
2.0
1.6
—
—
—
0
0
646
6567
0.98
0.17
1.3
1.3
—
—
—
0
0
21
186
1.13
0.17
1.4
1.1
6.0
5.8
nmol/l
0.07
21
178
28
253
1.11
0.16
1.1
1.1
—
—
—
0
0
5
70
0.71
0.16
1.6
1.4
137.6
94.7
nmol/l
—
5
52
48
515
0.93
0.16
3.1
3.2
1675.5
103.6
u/ml
0.67
40
434
30
329
0.91
0.16
1.1
1.1
—
—
—
0
0
52
556
0.93
0.16
1.0
1.0
—
—
—
0
0
50
467
1.07
0.15
1.3
1.2
—
—
—
0
0
80
842
0.95
0.15
1.2
1.3
—
—
—
0
0
6
76
0.79
0.15
1.7
1.5
—
—
—
0
0
85
809
1.05
0.15
1.2
1.2
—
—
—
0
0
180
1744
1.03
0.15
1.8
1.7
—
—
—
0
0
136
1311
1.04
0.15
3.1
2.4
73.7
71.1
e9/l
0.31
100
935
37
342
1.08
0.15
1.1
1.1
4.3
9.3
iu/ml
—
10
91
256
2625
0.97
0.14
1.1
1.1
—
—
—
0
0
7
87
0.80
0.14
1.1
1.1
—
—
—
0
0
101
968
1.04
0.14
1.1
1.1
3.8
3.0
u/ml
0.16
50
520
249
2552
0.97
0.14
3.7
4.5
1.0
1.0
mmol/l
0.05
233
2411
3409
33978
1.01
0.14
2.9
2.9
5.4
5.4
mmol/l
3.28
3156
32164
21
189
1.11
0.13
2.3
1.7
—
—
—
0
0
8
98
0.82
0.13
1.1
1.1
—
—
—
0
0
13
149
0.87
0.13
1.1
2.2
104.2
224.9
umol/l
—
8
75
98
941
1.04
0.13
1.3
1.3
128.3
111.4
titre
—
6
90
27
294
0.92
0.13
3.9
2.3
1.2
1.3
%
0.12
22
222
96
923
1.04
0.12
1.3
1.3
1386.7
1035.4
titre
—
6
41
10
116
0.86
0.12
1.0
1.0
—
—
—
0
0
1637
16265
1.01
0.11
5.0
5.0
0.7
0.7
%
0.01
1499
15198
65
621
1.05
0.11
1.9
2.4
7.4
7.4
ph
0.25
55
519
27
250
1.08
0.11
1.2
1.1
—
—
—
0
0
807
7993
1.01
0.10
1.3
1.3
7.7
7.4
u/ml
0.06
318
3492
87
901
0.96
0.10
1.9
1.8
—
—
—
0
0
4026
40325
0.99
0.10
7.0
7.4
22.9
23.3
u/l
0.81
3868
39237
205
2092
0.98
0.09
1.2
1.2
—
—
—
0
0
19
207
0.92
0.09
1.1
1.4
—
—
—
0
0
40
379
1.06
0.09
2.4
2.5
1.1
1.4
e9/l
2.27
19
221
16
145
1.10
0.09
1.6
1.9
—
—
—
0
0
280
2846
0.98
0.09
2.0
2.1
28.1
28.5
u/ml
0.05
273
2752
46
439
1.05
0.08
1.1
1.0
0.3
0.4
u/ml
—
5
66
6
56
1.07
0.08
1.0
1.0
—
—
—
0
0
198
1943
1.02
0.08
1.6
1.8
1.2
1.4
g/l
2.13
178
1827
13
144
0.90
0.08
1.0
1.3
—
—
—
0
0
5
63
0.79
0.08
7.2
7.3
—
—
—
0
0
10
88
1.14
0.08
1.0
1.1
—
—
—
0
0
6
74
0.81
0.07
1.2
1.5
—
—
—
0
0
21
225
0.93
0.07
1.0
1.2
320.0
180.0
titre
—
5
48
22
206
1.07
0.07
3.6
2.3
31.4
32.1
pg
0.26
22
206
140
1427
0.98
0.06
3.1
3.0
60.7
70.7
ng/l
1.42
130
1308
14
128
1.09
0.06
1.0
1.1
3.8
4.5
mg/g
1.27
14
123
95
973
0.98
0.06
7.3
7.2
1.4
1.4
%
0.45
95
968
24
226
1.06
0.06
1.0
1.2
—
—
—
0
0
57
589
0.97
0.06
2.0
2.2
—
—
—
0
0
17
183
0.93
0.06
2.1
2.3
—
—
—
0
0
276
2794
0.99
0.06
1.2
1.2
—
—
—
0
0
32
305
1.05
0.06
1.7
2.1
13.3
12.5
%
—
9
169
18
193
0.93
0.06
1.1
1.0
—
—
—
0
0
10
111
0.90
0.06
1.3
1.3
—
0.3
g/l
—
0
5
159
1616
0.98
0.06
3.2
3.4
41.6
35.2
ug/l
0.06
104
1066
32
334
0.96
0.05
1.1
1.1
—
—
—
0
0
13
141
0.92
0.05
1.2
1.4
—
—
—
0
0
46
474
0.97
0.04
1.1
1.1
0.5
1.7
u/ml
—
10
133
605
6083
0.99
0.04
1.6
1.5
—
—
—
0
0
16
150
1.07
0.04
2.5
2.0
—
—
—
0
0
11
101
1.09
0.04
1.1
1.4
—
—
—
0
0
3898
38948
1.01
0.04
8.9
9.5
38.9
39.4
%
4.63
3136
32607
10
109
0.92
0.04
2.2
1.8
—
—
—
0
0
28
269
1.04
0.04
6.8
6.4
—
—
—
0
0
51
523
0.97
0.04
4.4
3.9
135.9
100.3
u/ml
0.18
22
175
15
141
1.06
0.03
2.8
2.5
10.4
11.1
%
0.30
15
141
358
3558
1.01
0.03
1.3
1.4
—
—
—
0
0
38
369
1.03
0.03
1.4
1.6
40.3
39.8
g/l
0.20
30
335
621
6184
1.00
0.03
1.7
1.6
—
—
—
0
0
60
612
0.98
0.03
1.0
1.1
—
—
—
0
0
30
308
0.97
0.02
1.3
1.2
—
—
—
0
0
32
312
1.03
0.02
1.8
2.2
77.0
76.3
%
0.14
32
303
425
4239
1.00
0.01
1.7
1.7
—
—
—
0
0
39
383
1.02
0.01
1.6
1.6
23.3
7.7
u/ml
0.62
33
259
607
6081
1.00
0.01
1.6
1.5
—
—
—
0
0
830
8289
1.00
0.01
1.3
1.3
20.3
23.6
iu/ml
0.31
229
2527
52
513
1.01
0.01
1.5
2.2
—
—
—
0
0
10
94
1.06
0.01
1.7
2.2
—
—
—
0
0
18
174
1.03
0.00
1.4
1.2
—
—
—
0
0
198
1973
1.00
0.00
2.3
2.0
0.2
0.2
g/l
0.46
187
1862
262
2626
1.00
0.00
2.0
2.3
10.7
10.5
g/l
0.54
232
2431
11
108
1.02
0.00
3.6
2.0
—
—
—
0
0
12
122
0.98
0.00
1.0
1.0
—
—
—
0
0
12
122
0.98
0.00
1.0
1.0
—
—
—
0
0
12
122
0.98
0.00
1.0
1.0
—
—
—
0
0
20
198
1.01
0.00
1.4
2.0
16.3
176.0
ug/l
0.90
20
189
15
145
1.03
0.00
1.1
1.1
—
—
—
0
0
10
104
0.96
0.00
1.0
1.0
—
—
—
0
0
11
106
1.04
0.00
1.9
2.6
—
—
—
0
0
14
136
1.03
0.00
1.0
1.1
—
—
—
0
0
16
164
0.98
0.00
2.8
1.7
2.6
2.7
mg/l
0.07
16
157
13
133
0.98
0.00
1.0
1.1
—
—
—
0
0
13
133
0.98
0.00
1.1
1.2
—
—
—
0
0
33
327
1.01
0.00
1.2
1.2
—
—
—
0
0
37
371
1.00
0.00
1.2
1.2
0.1
1.2
u/ml
0.99
11
127
45
449
1.00
0.00
1.8
1.7
6368.0
8404.6
e6/l
0.47
39
326
48
481
1.00
0.00
1.1
1.0
0.3
1.2
u/ml
—
9
115
286
2863
1.00
0.00
2.5
2.6
—
—
—
0
0
1876
18763
1.00
0.00
4.7
4.9
2.0
2.0
e9/l
0.21
1699
17092
0
9
0.00
0.00
0.0
2.9
—
36.9
—
0
9
0
9
0.00
0.00
0.0
1.0
—
8.0
—
0
9
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
104.2
—
0
7
0
5
0.00
0.00
0.0
1.6
—
617.6
—
0
5
8
86
0.93
0.00
1.6
1.5
32.3
37.1
g/l
—
8
81
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
191.7
—
0
6
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
9
99
0.91
0.00
1.0
1.2
—
—
—
0
0
7
75
0.93
0.00
1.3
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
7.5
—
—
—
0
0
6
59
1.02
0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
69.2
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
4.2
—
0
7
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
6
69
0.87
0.00
1.2
1.6
—
—
—
0
0
7
70
1.00
0.00
1.1
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint O15_POSTPART_HAEMORRH_ANATOMY and mortality.

Females

Parameter HR [95% CI] p-value
O15_POSTPART_HAEMORRH_ANATOMY 0.525 [0.4, 0.68] < 0.001
Birth year 0.996 [0.99, 1.0] 0.323

During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 21640 females with O15_POSTPART_HAEMORRH_ANATOMY died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_POSTPART_HAEMORRH_ANATOMY.

N-year risk Females Males
1 0.046% No data
5 0.315% No data
10 0.742% No data
15 1.405% No data
20 2.702% No data

Relationships between endpoints

Index endpoint: O15_POSTPART_HAEMORRH_ANATOMY – Postpartum haemorrhage due to anatomy

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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