Perforation of tympanic membrane

H8_PERFORATION

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H72
  • Hospital discharge: ICD-9 3842
  • Cause of death: ICD-10 H72
  • Cause of death: ICD-9 3842

2 out of 7 registries used, show all original rules.

4120

4. Check minimum number of events

None

4120

5. Include endpoints

None

4120

6. Filter based on genotype QC (FinnGen only)

4120

Control definitions (FinnGen only)

Control exclude
H8_MIDDLEMASTOID

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H65-H75
Name in latin
Perforatio membranae tympanicae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 39492 18838 20408
Only index persons 35816 17317 18499
Unadjusted period prevalence (%)
Whole population 0.55 0.54 0.57
Only index persons 0.67 0.64 0.71
Median age at first event (years)
Whole population 38.96 43.48 34.79
Only index persons 39.96 44.51 35.70

-FinnGen-

Key figures

All Female Male
Number of individuals 4120 2297 1823
Unadjusted period prevalence (%) 0.79 0.78 0.80
Median age at first event (years) 50.83 48.08 54.30

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3676
Matched controls
36762
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Z01.1
ICD-10 Finland
Examination of ears and hearing
7.1
323.0
1256
2518
H65.3
ICD-10 Finland
Chronic mucoid otitis media
637.4
323.0
592
11
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
305.0
323.0
546
21
H66.0
ICD-10 Finland
Acute suppurative otitis media
21.7
323.0
1017
637
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
9222.4
323.0
2754
12
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
+∞
323.0
470
*
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
333.9
323.0
681
25
4141
FHL
Myringoplasty (also for reasons other than inflammation)
2023.7
323.0
349
*
H71
ICD-10 Finland
Cholesteatoma of middle ear
1299.6
323.0
353
*
DCD00
NOMESCO Finland
Myringoplasty
6176.4
323.0
952
*
3842A
ICD-9 Finland
Other disorders of tympanic membrane, Perforation of tympanic membrane
+∞
323.0
392
*
UDC00
NOMESCO Finland
Ear microscopy
16.5
323.0
1178
1020
H66.9
ICD-10 Finland
Otitis media, unspecified
12.0
323.0
687
690
DFF00
NOMESCO Finland
Pure tone audiometry
7.8
323.0
873
1417
H65.2
ICD-10 Finland
Chronic serous otitis media
547.4
308.8
303
6
H72.8
ICD-10 Finland
Other perforations of tympanic membrane
285.8
262.4
265
10
DC1AD
NOMESCO Finland
Temporalbone CT
59.3
254.2
300
55
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
45.3
238.8
296
71
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
134.9
214.0
228
18
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
23.7
203.7
297
136
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
102.7
202.7
222
23
H60.9
ICD-10 Finland
Otitis externa, unspecified
6.5
201.5
570
1007
4122
FHL
Tympanostomy (tympanic tube)
102.9
178.0
195
20
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
+∞
171.2
163
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.6
165.8
2205
13397
H72.1
ICD-10 Finland
Attic perforation of tympanic membrane
1691.9
162.7
157
*
DCD10
NOMESCO Finland
Tympanoplasty
398.8
154.4
154
*
H74.1
ICD-10 Finland
Adhesive middle ear disease
+∞
153.2
146
*
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
+∞
153.2
146
*
H65.0
ICD-10 Finland
Acute serous otitis media
27.9
152.2
211
80
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.7
144.1
1317
6294
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
3.3
140.1
847
3077
DCW99
NOMESCO Finland
Other operation on eardrum and middle ear
709.5
139.8
137
*
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
83.5
135.4
152
19
H72
ICD-10 Finland
Perforation of tympanic membrane
198.5
129.5
134
7
TDA90
NOMESCO Finland
Removal wax from ear
17.2
128.3
208
128
H60.3
ICD-10 Finland
Other infective otitis externa
11.1
128.3
252
241
DCA40
NOMESCO Finland
Fat patching or other similar technique without opening of tympanic membrane
1271.0
126.8
123
*
H65.9
ICD-10 Finland
Nonsuppurative otitis media, unspecified
124.4
122.9
132
11
H70.1
ICD-10 Finland
Chronic mastoiditis
+∞
119.4
114
*
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
15.1
114.9
196
137
38100
ICD-8 Finland
Otitis media without mention of mastoiditis, Acute
+∞
112.0
107
*
H60.8
ICD-10 Finland
Other otitis externa
8.0
107.5
256
342
H04
ICPC
Ear discharge
6.8
105.1
278
434
DGW00
NOMESCO Finland
Dilatation of eustachian tube
1047.5
104.8
102
*
H01
ICPC
Ear pain/earache
3.4
104.3
583
1957
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
22.6
103.4
152
70
S02CA02
ATC
flumetasone and antiinfectives; otic
4.8
102.6
370
840
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
15.3
92.9
157
107
J01CA04
ATC
amoxicillin; systemic
2.4
92.3
3063
24913
S09.2
ICD-10 Finland
Traumatic rupture of ear drum
58.5
91.6
108
19
H66.1
ICD-10 Finland
Chronic tubotympanic suppurative otitis media
102.8
91.4
100
10
38402
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) non definita
+∞
88.9
85
*
H73.1
ICD-10 Finland
Chronic myringitis
+∞
85.7
82
*
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
432.4
85.4
85
*
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
8.1
85.0
199
258
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
5.8
84.8
255
469
3821A
ICD-9 Finland
Suppurative and unspecified otitis media, Chronic tubotympanic suppurative otitis media
+∞
83.6
80
*
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
4.0
80.9
354
962
H66
ICD-10 Finland
Suppurative and unspecified otitis media
7.0
80.5
207
309
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
50.1
76.9
93
19
DEB25
NOMESCO Finland
Attico-antro-mastoidectomy and tympanoplasty
+∞
76.3
73
*
EMB30
NOMESCO Finland
Adenotomy
8.4
74.3
169
209
Z97.4
ICD-10 Finland
Presence of external hearing-aid
4.5
73.4
277
653
DEA10
NOMESCO Finland
Attico-antrotomy
+∞
73.2
70
*
DFF15
NOMESCO Finland
Speech audiometry
4.5
70.0
265
626
H60
ICD-10 Finland
Otitis externa
4.3
69.0
271
664
H29
ICPC
Ear symptom/complaint other
2.8
68.1
479
1844
J01DA01
ATC
[U] cefalexin; systemic
1.8
68.0
2272
17163
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.5
67.2
342
1049
DEB20
NOMESCO Finland
Attico-antro-mastoidectomy and tympanotomy
+∞
65.8
63
*
J01DB01
ATC
cefalexin; oral
2.0
65.4
2979
24934
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
+∞
64.8
62
*
H92.0
ICD-10 Finland
Otalgia
4.0
63.6
276
740
H74.2
ICD-10 Finland
Discontinuity and dislocation of ear ossicles
618.3
62.0
61
*
H61.2
ICD-10 Finland
Impacted cerumen
3.5
61.0
303
910
DEB10
NOMESCO Finland
Attico-antro-mastoidectomy
+∞
60.6
58
*
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
4.2
59.6
238
591
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
+∞
59.5
57
*
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
16.4
58.9
96
60
H92.1
ICD-10 Finland
Otorrhoea
56.0
55.8
66
12
4451
FHL
Guitar cutting
5.5
53.6
164
307
R01AD08
ATC
fluticasone; nasal
1.9
53.2
1043
6414
38210
ICD-8 Finland
Chronic otitis media with mastoiditis
+∞
51.2
49
*
J01MA02
ATC
ciprofloxacin; systemic
1.7
50.5
1346
9122
R01AD09
ATC
mometasone; nasal
1.7
48.8
1560
11125
H02
ICPC
Hearing complaint
2.4
47.8
460
2091
38199
ICD-8 Finland
Otitis media without mention of mastoiditis, Unspecified
+∞
47.0
45
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.9
46.7
202
539
H77
ICPC
Perforation ear drum
70.8
43.1
49
7
J01FA10
ATC
azithromycin; systemic
1.6
42.6
2006
15680
H73.0
ICD-10 Finland
Acute myringitis
28.0
42.5
58
21
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
4.4
42.1
160
379
J01DC02
ATC
cefuroxime; systemic
3.0
41.2
257
905
DAX08
NOMESCO Finland
Fitting of hearing aid
3.5
39.9
194
571
38700
ICD-8 Finland
Other disease of ear and mastoid process, Cholesteatoma of ear
+∞
39.6
38
*
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
9.6
39.6
82
87
H60.4
ICD-10 Finland
Cholesteatoma of external ear
29.8
39.6
53
18
H02AB06
ATC
prednisolone; systemic
1.6
37.7
1569
11736
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
37.6
959
6288
TDC10
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
+∞
37.6
36
*
ZXA10
NOMESCO Finland
Bilateral
1.9
36.5
662
3885
J01DA06
ATC
[U] cefuroxime; systemic
2.0
35.1
528
2891
DEB30
NOMESCO Finland
Radical mastoidectomy
350.5
35.0
35
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.5
34.3
293
1243
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
3.9
34.0
146
388
WX110
NOMESCO Finland
Local anesthesy
1.5
33.6
2368
19838
4145
FHL
Tympanomastoidectomy, includes possible tympanoplasty
+∞
33.4
32
*
ZXA05
NOMESCO Finland
Left side
1.7
33.3
868
5690
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
3.3
32.8
173
543
N02BE01
ATC
paracetamol; systemic, rectal
1.6
32.5
2949
26158
H69.0
ICD-10 Finland
Patulous Eustachian tube
25.3
32.3
45
18
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
2.2
31.3
335
1588
J01DA08
ATC
[U] cefaclor; oral
2.0
30.8
437
2334
J01FA09
ATC
clarithromycin; systemic
1.6
30.6
1047
7356
R5120
NOMESCO Finland
Preparation of an aid
3.9
30.5
129
338
J35.2
ICD-10 Finland
Hypertrophy of adenoids
5.2
30.2
95
185
1450
FHL
Otomicroscopy
15.5
29.9
49
32
UDC10
NOMESCO Finland
Tympanoscopy
304.8
29.8
30
*
R01BA52
ATC
pseudoephedrine, combinations; oral
1.6
29.5
972
6751
H70
ICPC
Otitis externa
4.3
29.4
112
267
3810A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Acute nonsuppurative otitis media
+∞
29.2
28
*
H71
ICPC
Acute otitis media/myringitis
6.3
29.2
79
128
ZXA00
NOMESCO Finland
Right side
1.6
28.7
895
6120
4144
FHL
Mastoidectomy or aticomastoidectomy
+∞
28.2
27
*
H66.2
ICD-10 Finland
Chronic atticoantral suppurative otitis media
+∞
28.2
27
*
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.6
28.1
897
6167
H02AB04
ATC
methylprednisolone; systemic
1.9
27.9
487
2799
DCW00
NOMESCO Finland
Removal of ventilating tube from tympanic membrane
283.6
27.8
28
*
4121
FHL
Tympanic puncture or parasentosis in general anesthesia or operating room
13.5
27.7
48
36
H90.8
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unspecified
11.2
27.5
52
47
H91.9
ICD-10 Finland
Hearing loss, unspecified
2.9
27.0
171
607
R01AD12
ATC
fluticasone furoate; nasal
1.6
26.9
957
6746
J01FF01
ATC
clindamycin; systemic
1.6
26.7
886
6139
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
26.3
1374
10550
3853A
ICD-9 Finland
Other disorders of middle ear and mastoid, Cholesteatoma of middle ear and mastoid
+∞
26.1
25
*
38400
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) acuta
+∞
26.1
25
*
H95.1
ICD-10 Finland
Other disorders following mastoidectomy
262.4
25.7
26
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
25.6
689
4515
SPAT1043
SPAT
Audiometry
2.0
25.4
356
1887
H13
ICPC
Plugged feeling ear
1.7
25.4
583
3653
DCA30
NOMESCO Finland
Exploration of middle ear
70.4
24.8
28
*
Z96.2
ICD-10 Finland
Presence of otological and audiological implants
70.4
24.8
28
*
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
24.7
571
3579
ZZG00
NOMESCO Finland
Graft of cartilage
43.1
24.6
30
7
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
3.6
24.1
112
320
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
3.5
23.7
115
340
H70.0
ICD-10 Finland
Acute mastoiditis
241.5
23.7
24
*
R03AC02
ATC
salbutamol; inhalant
1.4
23.6
1700
13818
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.5
23.1
195
819
1451
FHL
Otomicroscopy and paper place
+∞
22.9
22
*
J33.8
ICD-10 Finland
Other polyp of sinus
4.0
22.9
94
242
J01AA02
ATC
doxycycline; systemic
1.4
22.4
2514
22095
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
21.7
714
4902
H73.8
ICD-10 Finland
Other specified disorders of tympanic membrane
115.7
21.6
23
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
21.5
552
3551
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
21.4
380
2188
4150
FHL
Tympanoplasty (including for reasons other than inflammation)
60.4
20.9
24
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
20.1
1402
11216
N02AX02
ATC
tramadol; systemic, rectal
1.4
20.0
1286
10135
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.6
19.7
638
4350
74900
ICD-8 Finland
Cleft palate and cleft lip, Cleft palate
29.1
19.6
26
9
H95.0
ICD-10 Finland
Recurrent cholesteatoma of postmastoidectomy cavity
201.0
19.6
20
*
A02BC02
ATC
pantoprazole; systemic
1.4
19.3
2043
17509
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
19.3
667
4620
J32.4
ICD-10 Finland
Chronic pansinusitis
4.6
19.2
67
148
ZZF00
NOMESCO Finland
Graft of adipose tissue
6.6
19.2
49
75
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.4
18.9
1034
7885
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.3
18.8
186
847
H74.0
ICD-10 Finland
Tympanosclerosis
+∞
18.8
18
*
Q35.1
ICD-10 Finland
Cleft hard palate
27.9
18.7
25
9
H95.8
ICD-10 Finland
Other postprocedural disorders of ear and mastoid process
190.9
18.5
19
*
38798
ICD-8 Finland
Other disease of ear and mastoid process, Alii definiti
38.6
18.5
23
6
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
18.3
873
6473
SPAT1263
SPAT
Sampling
1.4
17.9
1374
11105
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.1
17.9
200
966
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.7
17.8
127
489
SPAT1301
SPAT
No procedures
1.4
17.7
1012
7758
J33.0
ICD-10 Finland
Polyp of nasal cavity
2.9
17.6
107
374
4742A
ICD-9 Finland
Chronic disease of tonsils and adenoids, Adenoid vegetations
3.9
17.5
73
192
ZXC10
NOMESCO Finland
Use of laser
3.3
17.4
89
276
UDM02
NOMESCO Finland
Sinoscopy
3.3
17.3
87
266
DEB00
NOMESCO Finland
Cortical mastoidectomy
42.2
17.3
21
5
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
17.3
232
1206
R01AD11
ATC
triamcinolone; nasal
1.8
17.2
284
1592
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
17.2
644
4527
R4135
NOMESCO Finland
Rehabilitation for hearing problems
4.0
17.0
69
177
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.5
17.0
583
4015
S02AA03
ATC
boric acid; otic
5.4
17.0
51
96
J01DC04
ATC
cefaclor; oral
4.3
16.9
62
145
H69.8
ICD-10 Finland
Other specified disorders of Eustachian tube
25.7
16.9
23
9
H61.8
ICD-10 Finland
Other specified disorders of external ear
4.9
16.9
55
114
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
3.3
16.5
85
265
DDD05
NOMESCO Finland
Plastic repair of ossicular chain
170.7
16.5
17
*
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
16.4
1689
14253
S18
ICPC
Laceration/cut
1.4
16.3
1283
10366
R42
ICD-10 Finland
Dizziness and giddiness
1.5
16.3
643
4569
J34.2
ICD-10 Finland
Deviated nasal septum
2.2
16.2
166
770
K02.1
ICD-10 Finland
Caries of dentine
1.3
16.0
1812
15485
L08
ICPC
Shoulder symptom/complaint
1.5
15.8
554
3833
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.5
15.8
582
4072
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
15.7
1092
8633
DCB00
NOMESCO Finland
Excision of lesion of middle ear
160.6
15.5
16
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
15.4
1283
10440
J01MA12
ATC
levofloxacin; systemic
1.5
15.2
542
3762
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
15.2
890
6822
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
15.1
393
2526
WX290
NOMESCO Finland
Other blockade of nerve
1.3
15.1
1358
11176
A02BC01
ATC
omeprazole; systemic
1.4
15.0
813
6138
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.7
15.0
299
1783
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
15.0
1501
12552
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.8
14.9
273
1584
R5140
NOMESCO Finland
Monitoring the use of the aid
1.7
14.8
310
1879
N06AX11
ATC
mirtazapine; oral
1.4
14.3
933
7277
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.4
14.1
119
503
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
14.0
1391
11581
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
14.0
2277
20337
SPAT1044
SPAT
Tympanometry
2.9
13.9
82
283
R74
ICPC
Upper respiratory infection acute
1.4
13.7
861
6659
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
13.7
1120
9049
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
13.6
1690
14504
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
13.6
1102
8882
R03BA05
ATC
fluticasone; inhalant
1.5
13.6
547
3891
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.6
13.6
404
2682
H73.9
ICD-10 Finland
Disorder of tympanic membrane, unspecified
75.4
13.6
15
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
13.6
622
4540
3824A
ICD-9 Finland
Suppurative and unspecified otitis media, Unspecified suppurative otitis media
+∞
13.5
13
*
DCA00
NOMESCO Finland
Biopsy of tympanic membrane or middle ear
+∞
13.5
13
*
DEB35
NOMESCO Finland
Radical mastoidectomy with tympanoplasty
+∞
13.5
13
*
J02AC01
ATC
fluconazole; systemic
1.3
13.5
1151
9349
H60.1
ICD-10 Finland
Cellulitis of external ear
4.2
13.5
51
124
R01AD05
ATC
budesonide; nasal
1.8
13.5
238
1365
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
13.5
1767
15269
AA1AD
NOMESCO Finland
CT of head and brain
1.4
13.5
674
5002
4129
FHL
Other measure in this category
140.5
13.5
14
*
H60.0
ICD-10 Finland
Abscess of external ear
7.4
13.4
31
42
DBB00
NOMESCO Finland
Excision of lesion of external auditory canal
12.8
13.4
23
18
WX704
NOMESCO Finland
Intubation
1.8
13.4
215
1197
R51.80
ICD-10 Finland
Headache
1.5
13.3
441
3008
J35.1
ICD-10 Finland
Hypertrophy of tonsils
3.1
13.2
71
231
N07CA01
ATC
betahistine; oral
1.8
13.1
209
1160
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.7
13.1
267
1602
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
13.1
522
3704
SPAT1153
SPAT
Removal of sutures
1.4
12.9
944
7476
H80.9
ICD-10 Finland
Otosclerosis, unspecified
4.8
12.9
42
88
H90.2
ICD-10 Finland
Conductive hearing loss, unspecified
7.4
12.9
30
41
DCB10
NOMESCO Finland
Freeing of adhesions of middle ear
50.2
12.8
15
*
SPAT1260
SPAT
Consultation of another employee
1.5
12.8
549
3951
SPAT1312
SPAT
General health counselling
1.3
12.8
1016
8150
D07AB02
ATC
hydrocortisone butyrate; topical
1.4
12.8
828
6429
R06AE07
ATC
cetirizine; oral
1.3
12.8
1329
11093
DHB20
NOMESCO Finland
Polypectomy of internal nose
3.6
12.8
56
156
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
12.7
714
5412
H80.0
ICD-10 Finland
Otosclerosis involving oval window, nonobliterative
4.8
12.5
41
87
4147
FHL
Radical surgery, cavity filling and middle ear and / or eardrum plastic
+∞
12.5
12
*
4143
FHL
Atticotomy or atticoanthromy through the ear canal
+∞
12.5
12
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
12.5
504
3583
R03DC03
ATC
montelukast; oral
1.5
12.5
467
3271
H74.4
ICD-10 Finland
Polyp of middle ear
130.4
12.4
13
*
SPAT1310
SPAT
Counselling related to known health issue
1.3
12.4
995
7990
WX400
NOMESCO Finland
Inhalation anesthesy
2.1
12.3
141
690
J01CE02
ATC
phenoxymethylpenicillin; oral
1.3
12.3
2249
20215
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
12.1
2071
18430
4741B
ICD-9 Finland
Chronic disease of tonsils and adenoids, Hypertrophy of tonsils and adenoids[HYPERTROPHIA TONSILLAE PHARYNGICAE]
3.8
12.0
50
134
SPAT1254
SPAT
Administration of medicine
1.5
11.9
456
3204
7490A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS COMPLETA]
46.8
11.9
14
*
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.8
11.9
191
1065
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
11.7
764
5929
H61.3
ICD-10 Finland
Acquired stenosis of external ear canal
9.6
11.7
23
24
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
11.7
1157
9564
P01AB01
ATC
metronidazole; oral, rectal
1.3
11.6
1144
9445
T16
ICD-10 Finland
Foreign body in ear
4.6
11.5
39
86
A02BC03
ATC
lansoprazole; oral
1.3
11.5
840
6635
3811A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic serous otitis media
+∞
11.5
11
*
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
11.5
637
4809
4151
FHL
Reoperation for chronic otitis media
120.4
11.4
12
*
DC1AA
NOMESCO Finland
Temporalbone X-ray examination
120.4
11.4
12
*
J01FA06
ATC
roxithromycin; oral
1.3
11.4
1184
9839
J01CA02
ATC
pivampicillin; oral
2.3
11.3
104
462
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
11.3
962
7775
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.4
11.2
754
5874
EBA00
NOMESCO Finland
Extraction of tooth
1.3
11.2
1014
8263
L15
ICPC
Knee symptom/complaint
1.4
11.2
604
4532
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.9
11.2
174
960
WX002
NOMESCO Finland
Sedation and analgesia
1.4
11.0
563
4185
X59
ICD-10 Finland
Exposure to unspecified factor
1.4
11.0
547
4047
A07AA02
ATC
nystatin; oral
1.8
10.8
171
950
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.5
10.7
362
2476
DEE00
NOMESCO Finland
Osseous fixation of hearing aid
60.2
10.6
12
*
DDA00
NOMESCO Finland
Stapedotomy
5.0
10.6
33
67
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
10.6
304
2003
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
10.6
385
2677
M31.3
ICD-10 Finland
Wegener granulomatosis
7.0
10.5
25
36
J45.1
ICD-10 Finland
Nonallergic asthma
1.7
10.5
204
1208
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.5
10.5
409
2883
H70.9
ICD-10 Finland
Mastoiditis, unspecified
+∞
10.4
10
*
EMB10
NOMESCO Finland
Tonsillectomy
1.8
10.4
173
978
H27
ICPC
Fear of ear disease
3.6
10.4
45
126
H65
ICD-10 Finland
Nonsuppurative otitis media
4.8
10.3
33
69
Q37.1
ICD-10 Finland
Cleft hard palate with unilateral cleft lip
16.1
10.3
16
10
J31.0
ICD-10 Finland
Chronic rhinitis
1.7
10.3
214
1295
J01MA14
ATC
moxifloxacin; systemic
1.6
10.3
245
1539
N05BA04
ATC
oxazepam; oral
1.3
10.2
713
5575
DC1BD
NOMESCO Finland
Temporal bone extensive CT
23.4
10.2
14
6
N05AH04
ATC
quetiapine; oral
1.4
10.2
482
3530
M79.6
ICD-10 Finland
Pain in limb
1.3
10.1
1030
8510
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.4
10.1
457
3319
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.6
10.0
274
1782
SPAT1229
SPAT
Assessment of need for aid
1.7
10.0
220
1352
D07AC01
ATC
betamethasone; topical
1.3
10.0
972
7977
J20
ICD-10 Finland
Acute bronchitis
1.6
10.0
267
1727
J32.2
ICD-10 Finland
Chronic ethmoidal sinusitis
4.4
10.0
35
81
R06.0
ICD-10 Finland
Dyspnoea
1.3
10.0
688
5370
4226
FHL
Posterior radical surgery and possible etmoidectomy
4.6
10.0
33
72
H74
ICPC
Chronic otitis media
40.2
10.0
12
*
G44.2
ICD-10 Finland
Tension-type headache
1.5
9.9
359
2491
SAA04
NOMESCO Finland
Special inverstigation of mouth
1.8
9.9
172
986
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
9.9
823
6608
R03BA02
ATC
budesonide; inhalant
1.4
9.8
498
3695
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
9.8
478
3520
R01AD01
ATC
beclometasone; nasal
1.4
9.8
418
3004
J21.9
ICD-10 Finland
Acute bronchiolitis, unspecified
4.1
9.7
36
88
A06AD11
ATC
lactulose; oral
1.5
9.7
379
2674
R06AX13
ATC
loratadine; oral
1.4
9.7
429
3100
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
9.7
681
5329
A03
ICPC
Fever
1.4
9.7
475
3501
8726A
ICD-9 Finland
Open wound of ear, Other specified parts of ear, without mention of complication[VULNUS MEMBRANAE TYMPANI, NON COMPLICATUM]
55.1
9.6
11
*
WZA90
NOMESCO Finland
Other doctors statement
1.3
9.6
690
5413
4222
FHL
Endonasal etmoidectomy
4.2
9.6
35
84
A02BC05
ATC
esomeprazole; systemic
1.3
9.6
1149
9679
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.5
9.6
376
2655
R96
ICPC
Asthma
1.6
9.5
244
1564
M25.5
ICD-10 Finland
Pain in joint
1.3
9.5
792
6354
L28
ICPC
Limited function/disability (L)
1.4
9.5
417
3011
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
9.5
842
6819
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
9.4
1187
10056
DBW99
NOMESCO Finland
Other operation on external auditory canal
100.3
9.4
10
*
H62.2*B36.9
ICD-10 Finland
Otomycosis NOS
+∞
9.4
9
*
Z97.8
ICD-10 Finland
Presence of other specified devices
5.8
9.3
25
43
M01AE02
ATC
naproxen; oral, rectal
1.2
9.3
1734
15373
R02
ICPC
Shortness of breath/dyspnoea
1.5
9.2
328
2265
SPAT1352
SPAT
Inspection, maintenance and instruction for use of hearing aid
3.3
9.2
45
139
L03
ICPC
Low back symptom/complaint
1.3
9.2
674
5309
ZZC00
NOMESCO Finland
Graft of fascia
13.7
9.2
15
11
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.5
9.1
364
2580
WX720
NOMESCO Finland
Own respiration
2.0
9.1
110
555
H69.9
ICD-10 Finland
Eustachian tube disorder, unspecified
8.3
9.0
19
23
X58
ICD-10 Finland
Exposure to other specified factors
1.4
9.0
397
2865
WX725
NOMESCO Finland
Noninvasive ventilation
1.9
9.0
134
728
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.5
9.0
350
2465
4610A
ICD-9 Finland
Acute sinusitis, Maxillary
3.0
9.0
50
170
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
8.9
2988
28285
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
8.9
880
7226
A02BA02
ATC
ranitidine; systemic
1.4
8.8
534
4076
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
2.4
8.8
70
292
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
3.1
8.7
45
145
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
8.7
120
634
R03AC03
ATC
terbutaline; inhalant
1.4
8.7
381
2745
L17
ICPC
Foot/toe symptom/complaint
1.3
8.7
707
5643
H62.2*B44.8
ICD-10 Finland
Otitis externa in aspergillosis
50.1
8.7
10
*
H02AB07
ATC
prednisone; oral
1.4
8.7
391
2837
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.3
8.6
980
8183
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.9
8.6
125
677
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.2
8.5
1232
10578
H93.1
ICD-10 Finland
Tinnitus
1.7
8.5
177
1071
50301
ICD-8 Finland
Chronic sinusitis, Maxillaris NUD
3.3
8.5
40
121
4362
FHL
Nozzle reconstruction
90.2
8.4
9
*
H74.3
ICD-10 Finland
Other acquired abnormalities of ear ossicles
90.2
8.4
9
*
R01BA51
ATC
phenylpropanolamine, combinations; oral
1.4
8.4
358
2570
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.4
8.3
400
2931
M03BX02
ATC
tizanidine; oral
1.2
8.3
1816
16298
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.6
8.3
200
1262
3851A
ICD-9 Finland
Other disorders of middle ear and mastoid, Adhesive middle ear disease
+∞
8.3
8
*
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
1.5
8.2
248
1654
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
8.2
627
4963
N06AX16
ATC
venlafaxine; oral
1.4
8.1
373
2714
SPAT1211
SPAT
Application of soft bandage
1.5
8.1
254
1709
H60.2
ICD-10 Finland
Malignant otitis externa
22.1
8.0
11
5
H72
ICPC
Serous otitis media
22.1
8.0
11
5
G47.3
ICD-10 Finland
Sleep apnoea
1.3
8.0
542
4210
R53
ICD-10 Finland
Malaise and fatigue
1.3
8.0
579
4543
R06AE09
ATC
levocetirizine; oral
1.4
8.0
404
2993
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
1.8
7.9
131
740
WX402
NOMESCO Finland
General anaesthesia
1.4
7.9
459
3478
N03AX16
ATC
pregabalin; oral
1.3
7.9
638
5082
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.3
7.9
716
5801
R06AX27
ATC
desloratadine; oral
1.3
7.8
767
6275
SBB10
NOMESCO Finland
Teeth copy
1.6
7.8
197
1258
L01
ICPC
Neck symptom/complaint
1.4
7.8
355
2582
N05CF01
ATC
zopiclone; oral
1.3
7.7
885
7377
N03AX12
ATC
gabapentin; oral
1.4
7.7
399
2967
R03BB04
ATC
tiotropium bromide; inhalant
1.5
7.7
255
1739
H05
ICPC
Bleeding ear
5.6
7.7
21
38
J01FA01
ATC
erythromycin; systemic
1.4
7.6
389
2884
SPAT1283
SPAT
Restricted health certificate
1.3
7.6
500
3865
H83.0
ICD-10 Finland
Labyrinthitis
11.9
7.6
13
11
DPA30
NOMESCO Finland
Sphenotomy
4.5
7.5
25
56
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
2.5
7.5
54
216
S02CA03
ATC
hydrocortisone and antiinfectives; otic
10.0
7.5
14
14
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
1.7
7.5
133
772
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.4
7.5
361
2652
DFF59
NOMESCO Finland
Other assessment of balance
3.6
7.4
31
86
J01MA01
ATC
ofloxacin; systemic
1.5
7.4
224
1496
R13
ICD-10 Finland
Dysphagia
1.6
7.4
171
1066
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.5
7.4
218
1448
DDA10
NOMESCO Finland
Exploration of ossicular chain
80.2
7.4
8
*
DBD10
NOMESCO Finland
Reconstruction of external auditory canal
80.2
7.4
8
*
7490B
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS INCOMPLETA]
80.2
7.4
8
*
46100
ICD-8 Finland
Acute sinusitis, Maxillaris
2.5
7.4
53
212
A04
ICPC
Weakness/tiredness general
1.4
7.4
360
2648
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.4
7.3
379
2816
DDD10
NOMESCO Finland
Interposition between malleus and stapes
+∞
7.3
7
*
E0000UV
ATC
NA
1.2
7.3
1160
10034
4224
FHL
Endonasal anthrostomy
3.0
7.2
38
126
GD1AD
NOMESCO Finland
Thorax CT examination
1.9
7.2
106
577
H92.2
ICD-10 Finland
Otorrhagia
6.2
7.2
18
29
UKC02
NOMESCO Finland
Cystoscopy
1.4
7.2
410
3096
ZFX00
NOMESCO Finland
Use of balloon dilatation
15.8
7.2
11
7
S29
ICPC
Skin symptom/complaint other
1.3
7.2
460
3540
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
1.8
7.2
119
677
C03CA01
ATC
furosemide; systemic
1.3
7.2
737
6060
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.5
7.2
231
1565
R52.9
ICD-10 Finland
Pain, unspecified
1.5
7.2
221
1486
Q90.9
ICD-10 Finland
Down syndrome, unspecified
30.1
7.1
9
*
Q35.71
ICD-10 Finland
Submucous cleft palate
30.1
7.1
9
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.5
7.1
269
1890
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.3
7.1
620
4992
L12
ICPC
Hand/finger symptom/complaint
1.4
7.1
387
2904
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
7.1
428
3263
4711A
ICD-9 Finland
Nasal polyps, Polypoid sinus degeneration
4.5
7.1
23
51
SPAT1262
SPAT
Handing over of treatment supplies
1.3
7.1
487
3791
H91.1
ICD-10 Finland
Presbycusis
1.7
7.1
148
904
4221
FHL
Polyp removal from the nasal cavity, sinus puncture or irrigation, or biopsy under general anesthesia or operating room
3.6
7.0
29
80
R05
ICPC
Cough
1.3
7.0
619
4988
B01AB05
ATC
enoxaparin; parenteral
1.3
7.0
824
6880
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.3
7.0
438
3359
SDA02
NOMESCO Finland
Parodonthologic therapy
1.2
7.0
925
7834
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.4
7.0
299
2148
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.5
6.9
205
1364
Z01.2
ICD-10 Finland
Dental examination
1.2
6.9
1209
10542
SPAT1360
SPAT
Extensive global examination
1.5
6.9
200
1321
H53.9
ICD-10 Finland
Visual disturbance, unspecified
2.0
6.9
79
394
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
3.2
6.9
34
108
J46
ICD-10 Finland
Status asthmaticus
2.1
6.9
76
371
M54.5
ICD-10 Finland
Low back pain
1.2
6.9
921
7806
DJD20
NOMESCO Finland
Plastic repair of septum of nose
1.9
6.8
95
508
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.2
6.8
1208
10539
4452
FHL
Tonsil surgery
2.0
6.8
83
424
R03AK08
ATC
formoterol and beclometasone; inhalant
1.8
6.8
101
554
T36
ICD-10 Finland
Poisoning by systemic antibiotics
1.7
6.8
121
703
J47
ICD-10 Finland
Bronchiectasis
2.4
6.8
55
235
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
1.8
6.8
110
621
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
6.8
645
5249
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.1
6.7
70
335
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.3
6.7
635
5164
H62.2
ICD-10 Finland
Otitis externa in mycoses
22.5
6.7
9
*
Q35.9
ICD-10 Finland
Cleft palate, unspecified
22.5
6.7
9
*
R09
ICPC
Sinus symptom/complaint
1.5
6.7
203
1358
N07BA03
ATC
varenicline; oral
1.7
6.6
127
756
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.2
6.6
1111
9638
E000001
ATC
NA
1.3
6.6
571
4586
H81.3
ICD-10 Finland
Other peripheral vertigo
2.0
6.6
77
388
SPAT1325
SPAT
Vaccination
1.2
6.6
1015
8727
R05FB02
ATC
cough suppressants and expectorants
1.2
6.5
1027
8853
R03AC12
ATC
salmeterol; inhalant
1.7
6.5
115
669
S01
ICPC
Pain/tenderness of skin
1.8
6.5
109
621
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.4
6.5
309
2267
D11
ICPC
Diarrhoea
1.4
6.5
302
2204
A10AE04
ATC
insulin glargine; parenteral
1.5
6.5
237
1654
S02
ICPC
Pruritus
1.8
6.4
98
544
ENC80
NOMESCO Finland
Plastic operation of soft palate for voice distubance
70.0
6.4
7
*
ECB17
NOMESCO Finland
Operation for cleft gingiva
70.0
6.4
7
*
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.5
6.4
245
1722
XW000
NOMESCO Finland
Bone marrow biopsy
1.8
6.4
103
581
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
2.0
6.4
73
365
7492A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate with cleft lip[CHEILOPALATOSCHISIS UNILATERALIS COMPLETA]
14.3
6.4
10
7
4364
FHL
Pharyngeal tongue plastic
14.3
6.4
10
7
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.2
6.4
1010
8702
N30.0
ICD-10 Finland
Acute cystitis
1.4
6.4
361
2728
N07BB01
ATC
disulfiram; oral
1.8
6.4
110
635
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
3.0
6.3
33
110
H03AA01
ATC
levothyroxine sodium; systemic
1.3
6.3
607
4942
DFF40
NOMESCO Finland
Otoneurologic examination of vertigo
5.2
6.3
18
35
SPAT1216
SPAT
Assessment of functional ability
1.3
6.3
402
3093
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
2.2
6.3
62
290
XG410
NOMESCO Finland
Flow-volume spirometry
1.7
6.3
111
646
H83.1
ICD-10 Finland
Labyrinthine fistula
18.0
6.3
9
5
B37.3
ICD-10 Finland
Candidiasis of vulva and vagina
3.0
6.3
33
111
DGW99
NOMESCO Finland
Other operation on eustachian tube
+∞
6.2
6
*
DBA00
NOMESCO Finland
Incision of external auditory canal
+∞
6.2
6
*
4146
FHL
Radical cutting (bridge broken)
+∞
6.2
6
*
Q90.0
ICD-10 Finland
Trisomy 21, meiotic nondisjunction
26.7
6.2
8
*
3890A
ICD-9 Finland
Deafness, Conductive deafness
26.7
6.2
8
*
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
2.1
6.2
62
293
B01AC04
ATC
clopidogrel; oral
1.3
6.2
393
3018
EBA10
NOMESCO Finland
Surgical removal of tooth
1.4
6.2
343
2579
K03.66
ICD-10 Finland
Tooth plaque
1.6
6.2
166
1081
N01
ICPC
Headache
1.4
6.2
291
2130
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.3
6.2
517
4135
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.0
6.2
75
383
S01AA01
ATC
chloramphenicol; ophthalmic (antibiotics)
1.6
6.2
137
850
SDA04
NOMESCO Finland
Very demanding parodonthologic therapy
1.3
6.2
625
5120
602
Kela drug reimbursment
Children's severe malnutrition
5.7
6.1
16
28
Z98.8
ICD-10 Finland
Other specified postsurgical states
2.7
6.1
38
142
L04AX01
ATC
azathioprine; systemic
1.7
6.1
115
683
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.6
6.1
145
918
N06AB04
ATC
citalopram; systemic
1.3
6.1
566
4588
A98
ICPC
Health maint/preventive medicine
1.3
6.0
3361
32654
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.2
6.0
740
6198
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.5
6.0
187
1258
A28
ICPC
Limited function/disability NOS
1.3
6.0
370
2829
SPAT1245
SPAT
Provision of support and information to patient’s family members
1.8
6.0
102
587
74920
ICD-8 Finland
Cleft palate and cleft lip, Cheilognathopalatoschisis unilateralis
10.0
6.0
11
11
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
1.9
6.0
76
395

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1139
3827
3.73
282.14
2.4
1.7
—
—
—
0
0
756
3796
2.21
76.28
1.7
1.4
—
—
—
0
0
834
4576
2.03
65.72
2.2
2.0
—
—
—
0
0
2825
24473
1.49
29.61
4.8
4.0
12.9
11.8
mm/h
3.37
2586
22648
2672
22975
1.46
28.43
5.0
4.2
—
—
—
0
0
2290
19270
1.42
26.37
5.5
4.6
6.8
6.7
mmol/l
0.80
2134
17941
1814
14648
1.43
26.31
7.0
5.9
1.2
1.2
mmol/l
0.24
1620
13273
1968
16151
1.42
25.92
8.1
6.6
1.2
1.2
mmol/l
0.64
1689
13634
1641
13094
1.42
25.05
2.1
2.0
95.0
95.4
pmol/l
0.10
857
6815
1448
11322
1.43
24.65
6.9
5.9
—
—
—
0
0
3632
33637
1.67
24.63
17.6
13.7
23.4
23.5
mg/l
0.06
2960
26447
2544
21945
1.42
24.61
4.9
4.4
1304.0
1781.0
e6/l
0.20
34
299
2858
25204
1.44
24.20
8.4
7.4
79.8
78.5
u/l
0.74
2684
23774
2076
17358
1.40
23.68
7.0
6.0
0.2
0.2
e9/l
3.32
1818
15236
2026
16888
1.39
23.44
6.5
6.1
12.0
11.5
umol/l
0.49
1911
15986
1316
10211
1.42
22.99
2.7
2.6
55.7
57.6
u/l
0.83
1220
9422
3644
33922
1.64
22.43
19.7
15.6
139.6
139.6
mmol/l
0.84
3544
33029
3650
34010
1.64
22.15
19.9
15.8
4.0
4.0
mmol/l
0.33
3546
33057
2053
17252
1.38
22.08
6.8
5.8
1.9
1.9
e9/l
0.45
1816
15178
1928
16040
1.38
22.04
6.7
5.9
56.9
56.9
%
0.00
1792
15044
829
5943
1.49
21.76
1.8
1.7
1102.7
1168.5
nmol/l
1.14
611
4468
2001
16794
1.37
21.44
6.8
5.8
0.0
0.0
e9/l
1.76
1743
14497
1947
16292
1.37
21.14
7.1
6.0
28.1
28.3
%
0.20
1810
15233
1992
16733
1.37
21.09
6.7
5.8
0.6
0.6
e9/l
2.18
1736
14445
1894
15815
1.37
20.67
7.4
6.3
8.6
8.6
%
0.15
1765
14855
1704
14029
1.37
20.17
5.6
4.8
35.5
35.6
g/l
0.52
1588
13040
1880
15723
1.36
20.10
7.0
6.0
3.0
2.8
%
1.43
1744
14689
1826
15252
1.35
19.46
7.1
6.0
0.7
0.7
%
0.59
1691
14275
1129
8748
1.40
19.15
4.8
4.3
—
—
—
0
0
2246
19407
1.35
18.90
9.7
8.9
4.3
4.1
e9/l
2.03
1976
16903
3318
30582
1.44
18.14
5.1
4.7
2.0
2.0
mu/l
0.19
3011
28121
480
3194
1.57
17.52
4.1
4.2
—
—
—
0
0
1222
9809
1.35
16.08
3.4
3.1
—
—
—
0
0
2491
22143
1.32
15.75
3.4
3.1
49.9
46.9
u/l
0.88
2326
20691
1549
12904
1.32
15.71
9.6
9.1
1.3
1.3
inr
0.10
429
3774
1624
13626
1.32
15.62
2.6
2.2
75.0
76.4
nmol/l
1.21
1445
12289
3735
35507
1.56
14.94
12.0
10.0
27.6
26.2
u/l
2.16
3588
34265
1193
9661
1.33
14.48
2.3
2.1
177.2
228.3
u/l
1.52
1109
9079
1446
12050
1.31
14.25
4.0
3.6
119.5
87.4
ng/l
0.18
984
8056
325
2074
1.62
14.09
1.5
1.3
304.1
209.7
u/ml
0.62
301
1906
2823
25719
1.31
13.89
4.2
4.0
14.8
14.7
pmol/l
0.71
2531
23383
184
1007
1.87
13.81
5.8
6.5
1.4
1.3
mmol/l
0.58
164
883
377
2508
1.55
13.68
3.4
2.6
10.3
10.5
g/l
0.21
347
2274
1307
10820
1.30
13.30
3.6
3.2
33.1
35.7
u/l
0.51
1234
10260
1175
9631
1.31
12.76
4.1
4.0
10.3
9.0
mg/mmol
0.37
748
6134
1807
15651
1.28
12.76
4.7
4.0
—
—
—
0
0
227
1357
1.71
12.67
2.7
1.4
18.9
15.9
u/ml
0.12
17
32
3372
31645
1.36
12.65
4.7
4.4
5.9
5.9
mmol/l
1.43
3062
28908
3190
29695
1.33
12.61
6.1
5.5
39.9
39.5
mmol/mol
1.62
2911
27520
3895
37574
1.67
12.54
25.1
19.9
30.2
30.2
pg
0.10
3828
37024
3895
37575
1.67
12.53
25.2
19.9
90.8
90.7
fl
0.63
3829
37029
3896
37588
1.67
12.52
25.3
20.0
7.0
6.7
e9/l
3.96
3793
36483
3895
37580
1.67
12.46
25.3
20.0
4.5
4.5
e12/l
3.39
3785
36494
3892
37547
1.66
12.41
25.3
20.0
252.1
251.7
e9/l
0.12
3797
36557
3895
37593
1.66
12.27
25.4
20.1
134.5
135.4
g/l
3.46
3833
37053
1114
9108
1.31
12.23
4.4
3.8
—
—
—
0
0
1048
8522
1.31
11.92
2.4
2.2
2.9
2.9
mg/l
0.09
889
7264
241
1495
1.65
11.71
5.2
4.0
—
—
—
0
0
1258
10506
1.28
11.62
2.7
2.4
—
—
—
0
0
1078
8833
1.30
11.52
3.2
3.0
1458.1
1420.2
ng/l
0.10
924
7548
570
4265
1.39
11.22
6.8
6.0
1.1
1.1
mmol/l
0.42
524
3969
134
709
1.92
11.21
6.4
7.7
11.2
11.3
mmol/l
0.12
119
635
134
710
1.92
11.17
6.4
7.7
104.8
105.3
mmol/l
0.48
119
636
312
2086
1.54
11.06
5.4
3.7
5.1
5.2
kpa
0.12
290
1930
307
2062
1.53
10.65
5.4
3.7
7.4
7.4
ph
0.40
23
246
3658
34981
1.41
10.61
16.6
12.8
—
—
—
0
0
1295
10962
1.26
10.47
3.4
3.3
2.3
2.4
mmol/l
1.62
1091
9616
924
7503
1.30
10.42
1.7
1.5
20.1
20.4
nmol/l
0.25
782
6444
1203
10101
1.27
10.40
3.6
3.3
7.6
7.6
mmol/l
0.17
1005
8523
584
4442
1.37
10.35
1.3
1.3
653.5
552.0
titre
0.50
130
909
207
1280
1.65
10.22
5.5
5.5
0.9
0.9
%
0.91
192
1202
3464
32897
1.33
10.04
4.9
4.7
2.7
2.8
mmol/l
1.90
3156
30366
324
2229
1.49
10.03
1.5
1.4
—
—
—
0
0
261
1715
1.56
10.01
10.7
9.8
—
—
—
0
0
205
1288
1.62
9.51
5.4
5.4
1.7
1.7
%
0.17
190
1205
209
1320
1.61
9.50
5.6
4.1
24.8
24.8
mmol/l
0.04
198
1224
291
1985
1.50
9.40
6.1
6.9
24.4
24.5
mmol/l
0.17
267
1849
3405
32327
1.31
9.38
4.4
4.2
4.6
4.6
mmol/l
4.14
3123
30021
1090
9144
1.26
9.30
3.4
3.3
426.1
336.4
mg/l
0.26
714
5833
371
2679
1.42
8.92
3.1
2.9
173.5
199.1
ng/l
0.65
335
2421
3377
32076
1.29
8.91
4.4
4.2
1.4
1.5
mmol/l
6.65
3082
29643
195
1233
1.61
8.84
1.3
1.2
1.4
1.1
u/ml
0.18
18
103
490
3714
1.36
8.82
2.8
2.8
10.1
8.1
umol/l
0.52
410
3210
371
2686
1.42
8.79
2.9
2.6
69.9
69.7
e9/l
0.03
284
2011
298
2075
1.47
8.70
4.8
4.9
—
—
—
0
0
642
5085
1.31
8.56
2.8
2.4
12.6
13.3
umol/l
1.49
602
4714
996
8355
1.25
8.36
2.7
2.6
3631.6
4878.1
umol/l
0.50
868
7247
478
3640
1.35
8.34
8.5
7.1
1.0
1.1
mmol/l
0.10
360
2837
284
1976
1.47
8.33
1.9
1.8
1.3
1.4
g/l
0.28
263
1800
765
6225
1.28
8.28
4.1
3.7
331.6
566.3
ng/l
0.69
586
4749
868
7176
1.27
8.25
4.2
4.0
1.0
1.0
kg/l
0.08
144
1072
1678
14890
1.21
8.21
3.2
2.8
129.9
120.8
ug/l
0.52
1542
13823
390
2887
1.39
8.12
9.1
7.5
10.2
9.6
mmol/l
0.76
369
2758
1447
12685
1.22
7.94
3.7
3.4
—
5.7
—
0
10
142
852
1.69
7.93
1.5
1.4
45.4
12.2
iu/ml
—
5
16
833
6882
1.26
7.92
1.7
1.7
74964657.6
27071102.6
pmol/l
1.06
699
5759
624
4975
1.30
7.88
2.1
2.2
29.5
29.8
s
0.45
603
4822
3259
30941
1.26
7.85
4.0
3.8
1.3
1.3
mmol/l
2.46
2956
28413
1117
9547
1.23
7.83
4.2
4.0
7.4
7.4
ph
0.24
165
1824
20
48
4.18
7.72
1.2
1.2
57.5
80.0
ng/l
0.20
15
32
953
8028
1.24
7.61
2.6
2.3
—
—
—
0
0
473
3647
1.34
7.59
8.5
7.1
5.1
5.1
kpa
0.36
444
3481
473
3647
1.34
7.59
8.5
7.1
12.0
12.4
kpa
0.84
442
3478
428
3252
1.35
7.57
9.0
7.5
95.7
95.6
%
0.21
404
3130
66
314
2.12
7.54
2.3
2.5
1.2
1.1
e9/l
0.53
44
182
1809
16260
1.20
7.51
4.0
3.6
0.0
0.0
estimate
1.08
287
3034
422
3205
1.35
7.49
4.8
3.8
—
7.4
—
0
11
1808
16258
1.20
7.45
5.5
4.9
0.0
0.0
estimate
0.50
299
3105
1826
16439
1.20
7.42
4.0
3.6
0.0
0.0
estimate
1.32
291
3014
397
2999
1.36
7.29
9.5
7.9
121.6
122.0
g/l
0.17
377
2891
191
1264
1.54
7.17
2.0
2.0
1.2
2.1
ug/l
0.99
168
1115
332
2446
1.39
7.12
4.4
3.9
90.7
87.3
ng/l
0.29
289
2112
93
512
1.84
7.03
3.7
3.5
0.8
1.6
%
3.37
75
394
222
1523
1.48
7.03
5.0
3.3
25.4
25.2
mmol/l
0.23
216
1473
32
113
2.85
6.94
1.3
1.2
—
—
—
0
0
406
3103
1.34
6.91
5.1
3.9
1.8
1.9
mmol/l
0.30
334
2513
582
4675
1.29
6.90
2.9
2.4
2.4
2.3
g/l
1.24
540
4329
856
7199
1.24
6.86
1.8
1.8
1.1
1.2
mg/l
0.93
638
5417
69
347
2.01
6.83
3.9
3.8
—
—
—
0
0
176
1158
1.54
6.80
3.1
3.3
0.4
0.3
g/l
0.32
78
489
147
928
1.61
6.79
1.7
1.6
0.2
0.2
g/l
0.12
139
877
53
242
2.21
6.74
2.3
2.1
11.6
13.4
%
0.70
30
112
546
4366
1.29
6.70
3.0
2.5
20.7
23.0
%
4.30
442
3735
64
316
2.04
6.67
3.4
3.6
64.0
57.1
%
1.76
44
202
405
3115
1.33
6.60
5.2
3.8
5.9
5.8
kpa
0.67
390
3024
516
4105
1.29
6.59
24.0
25.2
1.3
1.3
inr
0.01
94
577
636
5207
1.26
6.44
3.8
3.5
0.8
0.8
mmol/l
0.23
595
4858
465
3663
1.30
6.39
2.9
2.6
1.9
1.8
%
1.02
393
3230
299
2217
1.38
6.19
3.1
3.0
3.9
4.1
e9/l
0.69
209
1756
61
305
2.02
6.18
1.3
1.4
0.4
0.4
g/l
0.22
48
214
61
305
2.02
6.18
1.3
1.4
3.0
3.0
g/l
0.02
48
215
61
305
2.02
6.18
1.3
1.4
6.6
6.9
g/l
0.22
47
214
61
307
2.00
6.07
1.4
1.4
—
—
—
0
0
37
152
2.45
6.01
3.1
2.8
—
—
—
0
0
668
5541
1.25
6.01
1.3
1.3
36.6
32.2
iu/ml
0.26
203
1707
331
2510
1.35
5.95
4.1
3.9
0.5
0.6
%
0.62
88
552
147
959
1.55
5.94
1.7
1.6
1.2
1.2
g/l
0.38
139
907
979
8461
1.21
5.89
1.7
1.6
1.4
1.4
mmol/l
0.29
840
7156
59
299
1.99
5.78
1.2
1.1
—
—
—
0
0
356
2760
1.32
5.51
4.2
4.1
0.8
0.8
%
0.18
118
758
1131
9962
1.19
5.45
3.6
3.2
47.1
83.4
e6/l
1.50
875
7600
25
90
2.79
5.29
2.2
2.3
135.9
164.8
e6/l
0.26
17
44
33
137
2.42
5.28
1.0
1.1
9.0
7.8
u/ml
—
6
25
137
906
1.53
5.25
1.2
1.3
14.3
39.4
u/ml
—
10
51
70
390
1.81
5.19
1.3
1.4
300.6
284.4
pmol/l
0.16
51
301
346
2699
1.31
5.13
2.3
2.4
5.8
7.1
ug/l
0.96
284
2367
538
4435
1.25
5.10
1.2
1.2
—
—
—
0
0
1111
9828
1.18
5.03
5.1
4.9
2.8
3.3
ug/l
0.39
972
8816
123
803
1.55
5.02
4.2
3.1
23.7
24.9
mmol/l
2.08
109
697
261
1962
1.35
5.00
4.9
3.3
128.6
129.4
g/l
0.21
254
1912
59
316
1.88
4.97
1.3
1.2
—
—
—
0
0
624
5241
1.22
4.96
1.3
1.2
17.5
11.8
u/ml
0.85
222
2027
256
1923
1.35
4.94
1.3
1.2
—
—
—
0
0
71
404
1.77
4.93
1.3
1.3
—
—
—
0
0
335
2622
1.30
4.86
4.3
4.1
0.2
0.1
%
0.56
109
700
85
513
1.67
4.80
2.9
1.3
—
—
—
0
0
881
7670
1.19
4.78
3.8
3.6
—
—
—
0
0
1304
11727
1.16
4.75
4.2
3.6
76.6
95.3
e6/l
0.66
941
8190
22
79
2.79
4.71
1.9
2.3
—
—
—
0
0
208
1524
1.38
4.70
3.8
2.8
1.3
1.2
%
1.10
208
1510
330
2594
1.30
4.64
4.6
3.3
4.8
4.6
kpa
0.78
317
2511
3240
31178
1.18
4.63
18.5
14.5
39.4
39.9
%
1.83
2196
22817
125
835
1.51
4.62
1.3
1.3
15.0
3.5
u/ml
0.63
17
83
17
53
3.22
4.61
1.5
1.2
—
—
—
0
0
17
53
3.22
4.61
1.5
1.2
—
—
—
0
0
17
53
3.22
4.61
1.5
1.2
—
—
—
0
0
314
2466
1.30
4.46
4.3
4.1
0.0
0.4
%
1.00
90
590
70
410
1.72
4.44
4.6
2.5
—
—
—
0
0
156
1101
1.43
4.39
2.4
2.3
1497.1
473.9
ug/l
0.37
145
1031
125
847
1.49
4.34
1.3
1.3
14.8
9.1
u/ml
0.30
23
146
81
498
1.64
4.30
1.7
1.7
1.1
0.8
g/l
0.49
62
388
104
679
1.55
4.30
2.1
2.8
38.1
35.5
umol/l
0.26
81
579
382
3095
1.26
4.23
2.4
2.1
370.8
370.8
nmol/l
0.00
351
2831
52
284
1.84
4.18
2.6
3.0
43.4
42.5
mg/l
0.01
36
213
200
1486
1.36
4.18
3.6
2.7
0.7
0.7
%
0.05
192
1423
486
4050
1.23
4.17
9.0
6.6
104.8
104.4
mmol/l
0.99
474
3958
951
8421
1.17
4.15
7.6
6.7
—
—
—
0
0
327
2608
1.28
4.13
3.0
2.5
65.7
66.5
g/l
1.08
293
2393
127
876
1.46
4.06
1.4
1.4
532.6
509.6
mg/l
0.14
120
824
41
209
1.97
4.05
1.2
1.1
—
—
—
0
0
377
3071
1.25
3.99
2.1
2.3
0.2
0.2
g/l
0.07
347
2861
1045
11614
0.87
3.90
2.8
2.7
—
—
—
0
0
113
769
1.48
3.88
1.4
1.5
28.9
14.6
e6/l
0.32
90
593
113
769
1.48
3.88
1.5
1.5
776.5
1240.8
e6/l
0.27
97
627
56
322
1.75
3.84
2.8
2.7
—
—
—
0
0
48
264
1.83
3.81
2.1
2.3
37.8
42.2
%
—
9
30
68
414
1.65
3.79
1.6
1.5
72.4
53.0
mu/l
0.41
61
365
738
6448
1.18
3.78
3.2
2.7
553.9
548.7
mosm/kgh2o
0.23
621
5475
65
393
1.66
3.73
2.5
2.4
—
—
—
0
0
107
727
1.48
3.72
3.2
3.5
—
—
—
0
0
875
7764
1.16
3.68
1.3
1.3
1.4
1.6
u/ml
0.27
219
2035
782
6886
1.17
3.63
2.9
2.6
6.9
5.8
e6/l
0.83
681
6027
112
774
1.46
3.59
1.4
1.4
3.5
3.7
mmol/l
1.93
103
720
96
644
1.50
3.56
1.7
1.6
—
—
—
0
0
269
2137
1.28
3.54
2.2
2.3
—
—
—
0
0
770
6788
1.17
3.52
1.6
1.4
2.4
2.4
g/l
0.21
487
4139
35
179
1.96
3.47
1.8
1.4
1.4
1.2
nmol/l
0.24
29
140
47
265
1.78
3.47
1.9
1.4
1.2
1.3
promille
0.18
36
205
65
402
1.63
3.44
2.5
2.4
4.1
4.1
mmol/l
0.10
65
394
65
402
1.63
3.44
2.5
2.4
104.9
105.5
mmol/l
0.35
65
394
193
1473
1.33
3.44
1.9
1.8
1.4
1.5
g/l
0.57
164
1276
17
64
2.66
3.39
1.2
1.1
—
—
—
0
0
9
18
5.01
3.37
1.6
1.1
—
—
—
0
0
58
352
1.66
3.32
2.6
1.9
27.5
26.6
ug/l
0.03
58
346
129
930
1.40
3.31
1.3
1.4
253.8
287.2
ug/g
1.08
75
519
66
415
1.60
3.29
3.1
2.9
—
—
—
0
0
42
233
1.81
3.29
2.2
2.7
646.8
718.2
e6/l
0.34
20
98
104
728
1.44
3.16
2.8
2.1
126.5
130.1
g/l
0.75
71
534
65
413
1.58
3.12
1.3
1.3
—
—
—
0
0
81
541
1.51
3.11
1.3
1.5
—
—
—
0
0
603
5265
1.17
3.11
3.1
2.9
2.6
2.4
e6/l
0.19
345
2826
494
4243
1.19
3.10
2.5
2.4
159.6
130.9
ug/g
0.69
387
3354
484
4152
1.19
3.09
1.7
1.6
—
—
—
0
0
212
1666
1.29
3.08
2.5
2.4
—
—
—
0
0
107
757
1.42
3.08
1.6
1.6
12009.7
13724.3
e6/l
0.17
78
547
39
217
1.80
3.05
2.8
3.1
164.4
128.3
nmol/l
0.23
39
212
187
1451
1.30
3.00
2.3
2.3
6401.0
6038.8
u/l
0.03
74
554
39
219
1.79
2.96
1.2
1.2
—
—
—
0
0
69
452
1.54
2.92
1.3
1.3
0.6
0.6
nmol/l
0.63
63
433
1422
13215
1.12
2.82
2.1
2.1
—
—
—
0
0
128
950
1.36
2.81
1.1
1.1
18.6
4.0
u/ml
—
9
120
69
457
1.52
2.79
1.3
1.3
0.1
0.4
nmol/l
—
5
25
100
714
1.41
2.77
1.4
1.5
—
—
—
0
0
130
971
1.35
2.74
3.1
3.4
49.6
68.4
mg/l
0.45
112
788
35
196
1.79
2.71
2.2
2.6
0.2
0.2
e9/l
0.01
35
188
164
1270
1.30
2.70
5.2
4.4
—
—
—
0
0
93
659
1.42
2.69
4.3
3.2
8.2
7.5
mmol/l
1.28
93
639
151
1158
1.32
2.67
2.9
2.5
—
—
—
0
0
373
3176
1.19
2.62
1.5
1.4
—
—
—
0
0
633
5622
1.15
2.61
2.9
2.7
1.3
1.2
e6/l
0.10
378
3173
129
972
1.34
2.59
3.1
3.4
78.6
117.4
mg/l
0.25
111
787
379
3236
1.19
2.58
3.5
4.0
29.8
20.7
ug/l
0.30
305
2624
122
913
1.35
2.57
1.2
1.3
60.0
92.1
titre
—
8
76
60
394
1.53
2.56
1.3
1.3
—
—
nmol/l
—
0
0
5
7
7.15
2.55
1.0
1.1
—
—
—
0
0
145
1117
1.31
2.51
1.8
1.7
—
—
—
0
0
101
742
1.37
2.41
1.1
1.1
0.7
1.7
u/ml
1.37
49
315
996
9146
1.12
2.40
3.5
3.1
0.4
0.4
e6/l
0.55
743
6879
39
235
1.67
2.38
1.7
1.3
0.9
1.2
u/ml
0.11
25
99
150
1171
1.29
2.37
1.1
1.1
—
—
—
0
0
825
7501
1.12
2.36
5.2
4.3
—
—
—
0
0
630
5638
1.14
2.33
1.7
1.6
—
—
—
0
0
762
6902
1.13
2.32
2.0
1.9
—
—
—
0
0
119
904
1.33
2.30
5.9
4.6
1.5
1.4
mg/l
0.13
113
832
328
2798
1.19
2.28
11.3
7.9
—
—
—
0
0
419
3648
1.17
2.28
1.7
1.7
—
—
—
0
0
77
546
1.42
2.27
1.5
1.5
—
—
—
0
0
86
623
1.39
2.25
1.1
1.1
0.9
2.7
u/ml
2.23
24
154
45
286
1.58
2.24
1.2
1.1
52.9
43.5
mg/l
0.53
39
233
95
701
1.36
2.23
4.3
3.0
1.9
1.6
mmol/l
1.09
95
679
33
194
1.71
2.22
2.5
2.7
39.7
42.2
%
0.43
14
65
14
60
2.34
2.21
1.4
1.2
2.1
1.6
mmol/l
—
8
40
311
2654
1.19
2.17
3.8
3.5
—
—
—
0
0
54
362
1.50
2.14
1.2
1.5
—
—
—
0
0
122
943
1.30
2.11
3.1
3.4
1.7
1.7
ratio
0.00
14
70
205
1688
1.23
2.09
4.8
4.1
23.7
24.1
mmol/l
0.80
182
1539
31
183
1.70
2.07
1.6
1.5
—
—
—
0
0
9
31
2.91
2.07
1.0
1.2
—
—
—
0
0
87
643
1.36
2.05
1.1
1.1
1.2
1.3
u/ml
0.01
38
285
54
366
1.48
2.05
1.6
1.5
55.8
58.9
%
0.22
39
235
67
474
1.42
2.04
1.0
1.1
6.3
6.8
u/ml
0.06
33
197
137
1723
0.79
2.03
1.7
1.6
—
—
—
0
0
109
839
1.31
1.97
7.4
3.5
8.6
8.4
kpa
0.61
101
780
65
461
1.42
1.96
1.4
1.4
18.3
24.2
u/l
0.94
49
387
279
3253
0.85
1.95
1.3
1.3
—
—
—
0
0
14
64
2.19
1.94
2.6
2.0
—
—
—
0
0
963
8923
1.10
1.93
3.9
3.3
—
—
—
0
0
949
8788
1.10
1.93
4.6
4.0
0.0
0.0
estimate
1.28
293
2986
165
2016
0.81
1.91
1.3
1.4
—
—
—
0
0
330
2864
1.17
1.90
9.6
6.7
1.3
1.4
mmol/l
0.20
315
2755
31
188
1.65
1.90
4.6
3.6
—
—
—
0
0
93
704
1.33
1.90
3.2
3.1
—
—
—
0
0
15
72
2.09
1.86
1.1
1.9
-0.2
1.1
mmol/l
0.78
15
66
962
8931
1.10
1.85
3.4
3.0
—
—
—
0
0
89
673
1.33
1.84
1.1
1.1
4.3
5.7
u/ml
0.44
47
366
404
3570
1.15
1.83
1.3
1.3
—
—
—
0
0
12
249
0.48
1.81
1.1
1.1
—
—
—
0
0
648
5901
1.12
1.81
3.0
3.0
2.4
2.4
mmol/l
0.43
576
5167
33
207
1.60
1.79
1.0
1.0
—
—
—
0
0
40
264
1.52
1.76
1.2
1.3
2.0
2.0
mmol/l
0.01
35
247
14
67
2.09
1.75
2.2
1.4
—
—
—
0
0
22
124
1.78
1.75
2.0
2.1
—
—
—
0
0
71
523
1.36
1.75
1.0
1.1
3.5
4.6
u/ml
0.26
33
197
320
2791
1.16
1.75
1.2
1.2
—
—
—
0
0
2969
28958
1.09
1.74
22.2
17.4
332.3
332.7
g/l
1.07
2943
28725
75
558
1.35
1.74
1.1
1.1
—
—
—
0
0
9
36
2.50
1.74
1.6
1.5
—
—
—
0
0
51
355
1.44
1.73
1.6
1.8
—
—
—
0
0
23
132
1.75
1.73
1.3
1.8
2.1
2.0
umol/l
0.11
23
123
20
110
1.82
1.72
3.9
2.4
—
—
—
0
0
251
2152
1.18
1.71
3.1
3.0
—
—
—
0
0
42
282
1.49
1.71
1.5
1.4
12.5
12.0
mmol/l
0.17
11
67
46
315
1.47
1.70
4.3
3.5
—
—
—
0
0
34
218
1.56
1.70
1.2
1.3
12.8
11.6
u/l
0.27
29
200
168
1390
1.22
1.69
1.2
1.2
—
—
—
0
0
251
2155
1.18
1.69
1.2
1.2
—
—
—
0
0
240
2056
1.18
1.66
1.3
1.3
53.5
48.5
au/ml
—
10
79
260
2244
1.17
1.64
2.4
2.4
17.0
23.9
au/ml
0.87
15
126
34
220
1.55
1.64
1.0
1.1
—
—
—
0
0
29
181
1.61
1.63
3.0
2.5
7.4
7.4
ph
—
9
60
27
166
1.63
1.61
1.4
1.4
—
—
—
0
0
17
91
1.87
1.60
1.7
2.2
—
—
—
0
0
20
113
1.77
1.60
1.4
2.3
8.7
9.8
mg/l
0.39
15
96
46
320
1.44
1.59
1.1
1.1
—
—
—
0
0
16
84
1.91
1.59
1.0
1.2
45.8
38.6
g/l
—
5
46
20
114
1.76
1.56
2.6
2.5
—
—
—
0
0
52
372
1.40
1.55
1.6
1.5
—
—
—
0
0
52
372
1.40
1.55
1.6
1.5
—
—
—
0
0
52
372
1.40
1.55
1.6
1.5
—
—
—
0
0
52
372
1.40
1.55
1.6
1.5
—
—
—
0
0
91
710
1.29
1.55
1.6
1.3
295.4
252.2
u/ml
0.67
57
417
22
130
1.70
1.52
2.0
2.1
10.3
9.2
%
0.11
22
124
56
408
1.38
1.51
1.8
1.5
—
—
—
0
0
151
1256
1.21
1.48
1.5
1.6
—
—
—
0
0
9
38
2.37
1.45
1.3
1.8
50.7
43.7
umol/l
—
9
38
21
126
1.67
1.39
2.5
1.7
—
—
—
0
0
7
29
2.42
1.39
1.1
1.1
—
—
—
0
0
144
1201
1.21
1.39
1.5
1.3
—
—
—
0
0
196
1681
1.17
1.38
13.2
9.0
24.3
24.4
mmol/l
0.02
179
1578
11
53
2.08
1.38
1.8
2.2
3.4
3.2
ug/l
—
5
20
16
89
1.80
1.37
2.3
2.5
—
—
—
0
0
279
2461
1.14
1.36
2.2
2.1
11.8
12.6
nmol/l
0.77
239
2185
149
1250
1.20
1.36
2.2
2.3
21.8
21.5
s
0.29
133
1085
5
17
2.94
1.36
5.4
10.4
271.8
207.4
e6/l
—
5
11
65
497
1.31
1.32
4.8
5.0
386.7
366.4
umol/l
0.46
55
433
88
701
1.26
1.31
1.8
1.5
—
—
—
0
0
172
1468
1.18
1.30
1.9
1.9
—
—
—
0
0
22
138
1.60
1.26
1.1
1.1
95.7
454.4
ng/l
—
6
33
74
581
1.28
1.25
3.6
2.8
—
—
—
0
0
2325
22606
1.07
1.25
3.8
3.7
—
—
—
0
0
135
1133
1.20
1.25
2.3
2.3
10.1
10.2
g/l
0.07
107
962
72
564
1.28
1.24
1.1
1.1
222.9
942.1
iu/ml
0.40
15
147
34
237
1.44
1.22
2.4
2.4
—
—
—
0
0
39
280
1.40
1.20
1.4
1.3
1.7
1.5
nmol/l
0.59
31
254
13
71
1.83
1.19
1.2
1.1
—
—
—
0
0
8
38
2.11
1.18
1.6
3.5
—
—
—
0
0
80
642
1.25
1.15
1.7
1.5
109.7
115.6
u/ml
0.22
16
124
43
576
0.74
1.14
1.7
1.6
—
—
—
0
0
22
143
1.54
1.11
1.5
1.6
—
—
—
0
0
7
31
2.26
1.10
1.0
1.1
—
—
—
0
0
294
2645
1.12
1.09
1.5
1.4
—
—
—
0
0
113
947
1.20
1.09
3.9
3.3
—
—
—
0
0
71
567
1.26
1.08
1.1
1.1
—
—
—
0
0
22
144
1.53
1.08
8.4
14.2
—
—
—
0
0
881
8339
1.07
1.07
4.7
3.9
91.6
89.7
%
1.36
858
8130
1541
14849
1.06
1.07
10.5
9.3
0.0
0.0
e9/l
0.05
1256
12069
65
515
1.27
1.06
2.1
1.9
—
3.7
—
0
8
60
471
1.28
1.05
2.4
2.3
8.0
7.5
umol/l
0.09
41
348
455
4201
1.09
1.03
1.3
1.3
—
—
—
0
0
9
46
1.96
1.03
2.1
1.8
27.6
43.5
pmol/l
—
9
37
185
1624
1.15
1.03
3.6
3.4
55.1
53.1
u/ml
0.04
176
1565
35
474
0.74
1.02
1.3
1.2
—
—
—
0
0
56
438
1.28
1.02
1.0
1.1
0.0
0.4
u/ml
2.56
13
110
9
47
1.92
1.02
6.7
6.0
61.4
36.9
g/mol
—
9
41
229
2041
1.13
1.01
2.9
3.3
4.3
4.5
pmol/l
2.26
200
1821
68
546
1.25
1.01
1.5
1.7
—
—
—
0
0
40
299
1.34
1.00
1.5
1.3
134178.0
95952.1
e6/l
0.15
23
209
96
802
1.20
0.98
5.9
4.3
—
—
—
0
0
7
134
0.52
0.98
2.3
3.0
1.5
1.3
ug/l
—
7
125
22
148
1.49
0.97
2.7
1.7
1.8
7.5
nmol/l
1.08
22
121
7
36
1.95
0.97
1.0
1.1
—
—
—
0
0
15
92
1.63
0.97
1.9
2.1
—
—
—
0
0
9
50
1.80
0.96
1.1
1.2
—
—
—
0
0
24
166
1.45
0.94
1.1
1.3
68.2
74.5
%
—
6
19
6
120
0.50
0.93
1.2
1.1
—
—
—
0
0
12
70
1.72
0.92
2.8
2.9
—
—
—
0
0
2864
28150
1.06
0.92
20.8
16.5
13.8
13.6
%
3.24
2803
27537
23
159
1.45
0.91
1.4
1.1
1304.9
1482.7
miu/ml
0.34
23
159
23
159
1.45
0.91
2.7
3.7
—
—
—
0
0
15
94
1.60
0.90
1.2
1.5
—
—
—
0
0
87
729
1.20
0.89
1.2
1.2
—
—
—
0
0
169
1493
1.14
0.89
1.4
1.4
26.3
24.6
iu/l
0.31
148
1243
40
306
1.31
0.88
1.7
1.6
—
—
—
0
0
5
105
0.48
0.88
1.0
1.1
—
—
—
0
0
25
177
1.41
0.88
2.5
3.5
—
—
—
0
0
6
30
2.00
0.87
5.0
5.5
4.0
2.5
mg/l
—
6
24
12
72
1.67
0.85
1.2
1.1
0.8
0.7
umol/24h
—
6
40
12
191
0.63
0.84
1.1
1.2
—
—
—
0
0
100
854
1.18
0.84
1.9
2.0
12.8
11.2
mg/l
0.35
94
788
10
57
1.76
0.83
1.9
2.6
15.7
14.8
ml/dl
—
10
52
113
1305
0.86
0.83
1.1
1.1
—
—
—
0
0
257
2339
1.11
0.83
1.2
1.2
112.0
148.3
iu/ml
0.78
89
848
79
662
1.20
0.82
4.3
3.7
56.3
57.4
%
0.35
79
662
30
223
1.35
0.81
1.0
1.1
0.2
2.0
u/ml
1.08
13
76
15
97
1.55
0.81
3.1
2.2
2116.7
21310.7
e6/l
—
6
54
8
47
1.70
0.80
2.4
3.0
—
—
—
0
0
82
692
1.19
0.80
4.3
3.1
—
—
—
0
0
46
365
1.26
0.79
6.4
7.8
7.1
7.3
mmol/l
0.11
34
307
17
114
1.49
0.79
1.1
1.1
—
—
—
0
0
63
519
1.22
0.79
1.2
1.2
25.4
40.2
u/l
0.64
53
446
33
251
1.32
0.78
1.1
1.2
—
—
—
0
0
14
90
1.56
0.78
1.0
1.1
—
—
—
0
0
28
208
1.35
0.77
1.0
1.0
—
—
—
0
0
306
2823
1.09
0.76
1.5
1.4
—
—
—
0
0
54
440
1.23
0.75
1.1
1.1
1.6
1.5
g/l
0.78
45
393
25
183
1.37
0.75
2.0
2.9
—
—
—
0
0
244
2668
0.91
0.75
4.1
3.7
1.2
1.2
mmol/l
0.25
213
2318
5
24
2.08
0.74
1.0
1.5
358.0
346.5
umol/24h
—
5
24
17
116
1.47
0.74
2.2
2.1
50.7
66.4
ug/l
0.58
17
111
68
569
1.20
0.74
1.5
1.4
62.8
64.1
mmol/l
0.09
49
465
59
487
1.21
0.73
1.2
1.2
—
—
—
0
0
109
950
1.15
0.73
4.0
3.9
3.9
3.9
mmol/l
0.00
104
884
84
718
1.17
0.72
4.8
3.4
28.8
26.4
mg/l
0.27
55
460
7
39
1.80
0.72
1.0
1.3
—
—
mmol/l
—
0
0
6
110
0.54
0.72
1.0
1.1
—
—
—
0
0
88
757
1.17
0.71
5.0
3.6
—
—
—
0
0
35
274
1.28
0.69
1.9
3.1
11.7
11.2
%
0.32
35
274
5
27
1.85
0.68
1.4
1.2
—
—
—
0
0
47
384
1.23
0.66
1.5
1.4
3165.4
1683.1
e6/l
1.19
41
277
336
3140
1.08
0.64
2.8
2.4
36.7
37.9
u/l
0.12
293
2688
88
765
1.15
0.64
1.3
1.4
—
—
—
0
0
39
314
1.24
0.63
1.4
1.2
—
—
—
0
0
27
208
1.30
0.62
5.6
6.8
—
—
—
0
0
20
147
1.36
0.61
1.1
1.1
—
—
—
0
0
29
226
1.29
0.61
1.1
1.0
—
—
—
0
0
19
139
1.37
0.60
1.3
1.8
25.8
30.5
umol/l
2.11
19
134
66
768
0.86
0.59
1.4
1.4
—
—
—
0
0
25
192
1.30
0.59
1.6
1.4
5.1
7.6
u/l
1.41
20
164
68
789
0.86
0.59
1.4
1.5
—
—
—
0
0
14
97
1.44
0.59
1.2
1.5
—
—
—
0
0
75
650
1.16
0.58
3.1
3.4
1435.6
711.5
u/ml
0.30
69
597
30
237
1.27
0.58
1.0
1.1
—
—
—
0
0
127
1141
1.12
0.58
3.7
3.4
1319.2
3668.8
u/ml
0.44
111
963
24
184
1.31
0.57
1.8
2.5
19.1
26.2
umol/l
—
5
17
78
680
1.15
0.56
1.7
2.2
1.0
0.8
nmol/l
1.17
64
569
66
764
0.86
0.56
1.4
1.4
—
—
—
0
0
10
65
1.54
0.55
1.1
1.4
—
—
—
0
0
12
82
1.46
0.54
1.1
1.2
245.0
407.4
ug/l
—
5
42
6
39
1.54
0.53
1.3
1.5
—
—
—
0
0
38
313
1.22
0.53
1.9
2.1
—
—
—
0
0
385
3647
1.06
0.52
1.3
1.4
—
—
—
0
0
6
40
1.50
0.51
1.0
1.2
3.0
1.7
umol/24h
—
6
40
55
640
0.86
0.51
3.3
3.1
0.8
0.8
nmol/l
0.07
48
486
17
126
1.35
0.51
2.3
3.3
53.5
61.0
au/ml
—
5
20
49
417
1.18
0.49
1.9
1.7
—
—
—
0
0
10
144
0.69
0.49
1.6
1.4
—
—
—
0
0
7
45
1.56
0.49
13.7
12.8
4.8
6.3
mmol/l
—
7
45
7
46
1.52
0.48
1.1
1.2
—
—
—
0
0
26
208
1.25
0.47
1.7
1.4
1981.9
1979.6
ml
—
10
41
63
550
1.15
0.47
1.3
1.1
—
—
—
0
0
34
281
1.21
0.47
1.1
1.1
—
—
—
0
0
10
68
1.47
0.47
4.1
8.1
—
—
—
0
0
36
300
1.20
0.46
1.7
1.5
—
—
—
0
0
7
49
1.43
0.46
5.1
8.2
—
—
—
0
0
63
552
1.14
0.45
1.3
1.1
—
—
—
0
0
12
164
0.73
0.45
1.0
1.1
—
10.5
—
0
20
20
157
1.28
0.43
1.1
1.1
—
5.3
—
0
9
5
32
1.56
0.42
1.0
1.3
—
5.9
—
0
19
0
16
0.00
0.41
0.0
3.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.5
—
15.7
—
0
17
5
34
1.47
0.40
1.4
2.8
—
—
—
0
0
8
60
1.33
0.40
1.1
1.1
—
—
—
0
0
115
1055
1.09
0.40
1.6
1.4
9.4
9.2
u/l
0.07
96
838
42
362
1.16
0.39
1.4
1.5
279.4
280.7
mosm/kgh2o
0.12
30
273
20
160
1.25
0.38
1.9
2.0
—
—
—
0
0
9
67
1.34
0.38
1.7
2.4
—
—
—
0
0
12
89
1.35
0.37
3.8
2.3
—
—
—
0
0
273
2872
0.95
0.37
4.7
3.9
—
—
—
0
0
8
112
0.71
0.37
1.4
1.1
—
—
—
0
0
8
114
0.70
0.37
1.1
1.0
—
—
—
0
0
20
161
1.24
0.37
1.6
1.7
—
—
—
0
0
15
116
1.29
0.37
1.2
1.1
4.5
2.5
u/ml
—
10
66
53
469
1.13
0.36
1.5
1.4
2.3
3.9
ug/l
1.94
48
425
948
9705
0.97
0.35
1.5
1.5
—
—
—
0
0
54
479
1.13
0.35
1.2
1.2
4.7
4.9
u/ml
0.03
27
213
26
217
1.20
0.35
1.0
1.1
0.4
3.9
u/ml
0.88
11
61
39
338
1.16
0.35
1.5
1.4
25032.1
82221.7
e6/l
1.36
24
199
33
282
1.17
0.35
1.4
1.1
356.2
383.6
nmol/l
0.26
24
250
14
108
1.30
0.35
1.1
1.3
42.2
53.6
%
—
9
97
6
43
1.40
0.35
20.0
9.5
—
—
—
0
0
115
1065
1.08
0.34
4.5
3.2
—
—
—
0
0
549
5667
0.96
0.34
3.0
3.0
0.9
0.8
ug/l
0.69
386
3738
114
1056
1.08
0.34
11.9
9.8
—
—
—
0
0
17
136
1.25
0.33
1.4
4.0
178.5
71.8
mg/l
—
10
97
84
768
1.10
0.33
1.9
2.4
105.3
81.0
ug/min
0.27
46
480
6
46
1.30
0.33
1.8
1.7
—
—
—
0
0
6
88
0.68
0.33
5.8
3.0
—
—
—
0
0
168
1583
1.06
0.32
2.8
2.3
—
—
—
0
0
43
486
0.88
0.31
1.0
1.0
2.4
2.2
u/ml
0.09
16
222
14
110
1.27
0.31
3.2
2.5
634.8
756.7
e6/l
—
8
85
12
153
0.78
0.30
2.8
2.4
9.7
9.2
mmol/l
—
6
121
8
106
0.75
0.29
1.3
1.3
—
—
—
0
0
108
1007
1.07
0.29
1.2
1.2
—
—
—
0
0
16
130
1.23
0.28
1.0
1.0
—
—
—
0
0
168
1591
1.06
0.28
2.7
2.1
—
—
—
0
0
38
336
1.13
0.28
2.2
2.3
—
—
—
0
0
57
517
1.10
0.28
1.4
1.5
0.3
0.4
nmol/l
1.83
46
412
8
64
1.25
0.27
1.0
1.2
—
131.3
—
0
9
102
952
1.07
0.27
2.1
2.2
37.6
37.7
g/l
0.10
89
820
168
1595
1.06
0.27
2.8
2.3
—
—
—
0
0
23
196
1.17
0.27
1.2
1.2
—
—
—
0
0
33
290
1.14
0.27
1.2
1.5
39.9
32.1
%
0.50
22
185
66
719
0.92
0.27
1.4
1.3
—
—
—
0
0
55
500
1.10
0.26
1.2
1.2
—
—
—
0
0
13
104
1.25
0.26
4.8
4.8
—
—
—
0
0
12
95
1.26
0.26
1.1
1.3
—
—
—
0
0
157
1654
0.95
0.26
1.2
1.1
15.1
184.4
titre
—
8
39
5
71
0.70
0.26
1.6
1.6
—
—
—
0
0
43
386
1.12
0.26
1.3
1.2
—
—
—
0
0
102
956
1.07
0.25
1.8
1.8
39.1
40.3
nmol/l
0.23
95
927
12
96
1.25
0.24
1.8
1.7
—
—
—
0
0
10
126
0.79
0.24
1.2
1.2
—
0.3
g/l
—
0
9
139
1319
1.06
0.24
1.7
1.6
344.2
298.5
mu/l
0.66
126
1198
5
38
1.32
0.23
1.0
1.1
—
—
—
0
0
5
39
1.28
0.23
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
5.9
—
0
5
0
11
0.00
0.21
0.0
2.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
387.9
—
0
10
155
1482
1.05
0.21
2.9
2.3
—
—
—
0
0
48
440
1.09
0.21
1.7
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
0.0
—
0
5
20
173
1.16
0.20
1.5
1.3
144.3
133.5
nmol/l
0.51
20
173
10
80
1.25
0.20
1.0
1.1
—
—
—
0
0
10
80
1.25
0.20
1.0
1.1
—
—
—
0
0
10
80
1.25
0.20
1.0
1.1
—
—
—
0
0
55
594
0.92
0.20
1.1
1.2
—
—
—
0
0
10
123
0.81
0.20
1.0
1.0
—
—
—
0
0
19
164
1.16
0.20
1.6
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
6
48
1.25
0.20
1.2
1.0
—
—
—
0
0
29
259
1.12
0.20
1.6
2.3
797.3
625.6
ml
1.47
20
175
23
202
1.14
0.20
1.2
1.2
—
—
—
0
0
15
176
0.85
0.19
1.7
1.8
—
—
—
0
0
6
51
1.18
0.19
4.8
5.7
—
—
—
0
0
23
203
1.13
0.19
1.0
1.0
727.5
683.2
ng/l
0.20
12
127
7
60
1.17
0.17
1.6
1.4
—
—
—
0
0
36
329
1.10
0.17
4.3
4.8
18.2
80.6
u/ml
—
7
90
14
163
0.86
0.17
1.0
1.1
—
—
—
0
0
27
243
1.11
0.17
1.3
1.4
—
—
—
0
0
72
763
0.94
0.17
2.5
2.1
—
—
—
0
0
23
205
1.12
0.17
1.0
1.0
290.6
317.7
ng/l
0.26
13
132
23
206
1.12
0.16
1.1
1.1
1.1
1.0
ratio
—
10
71
162
1565
1.04
0.15
1.9
2.2
—
—
—
0
0
9
82
1.10
0.15
1.2
1.1
—
—
—
0
0
169
1638
1.03
0.14
4.6
3.4
—
—
—
0
0
70
665
1.05
0.14
1.2
1.3
—
—
—
0
0
53
499
1.06
0.14
3.1
3.9
45.4
33.4
u/ml
0.28
48
485
94
902
1.04
0.13
1.2
1.1
—
—
—
0
0
13
113
1.15
0.13
3.1
2.8
34.8
28.9
umol/l
—
8
85
11
94
1.17
0.13
1.1
1.1
—
—
—
0
0
87
836
1.04
0.12
1.1
1.1
—
—
—
0
0
40
376
1.06
0.11
1.4
1.3
—
—
—
0
0
382
3765
1.02
0.10
1.7
1.7
—
—
—
0
0
17
154
1.10
0.10
1.1
1.3
—
—
—
0
0
5
44
1.14
0.10
1.2
1.1
—
—
—
0
0
43
408
1.05
0.09
2.6
2.4
—
—
—
0
0
31
291
1.07
0.09
1.2
1.2
—
—
—
0
0
5
48
1.04
0.09
1.0
1.4
92.8
102.3
ng/l
—
5
48
16
145
1.10
0.09
1.1
1.1
163.6
198.3
iu/ml
0.26
16
145
24
257
0.93
0.08
1.9
2.1
1.1
1.8
u/field
—
10
98
117
1200
0.97
0.08
1.5
1.4
—
—
—
0
0
7
65
1.08
0.08
1.1
1.0
—
—
—
0
0
17
156
1.09
0.08
1.9
2.4
24.3
220.8
ug/l
0.67
17
141
14
127
1.10
0.07
1.3
1.6
—
—
—
0
0
34
323
1.05
0.07
1.3
1.1
—
—
—
0
0
41
392
1.05
0.07
2.0
2.1
32.7
32.5
pg
0.07
41
387
93
906
1.03
0.07
6.5
4.2
7.4
7.4
ph
0.16
76
763
9
85
1.06
0.07
1.3
1.5
—
—
—
0
0
17
157
1.08
0.07
1.2
1.2
—
—
—
0
0
9
88
1.02
0.07
1.3
1.4
—
—
—
0
0
8
92
0.87
0.06
1.3
1.5
10.7
25.5
%
—
8
84
79
771
1.03
0.05
5.7
4.4
2.7
2.6
mmol/l
0.02
62
517
23
242
0.95
0.05
1.1
1.4
54.6
182.9
pmol/l
—
10
79
115
1131
1.02
0.04
1.4
1.3
215.9
225.8
miu/ml
0.12
49
519
123
1249
0.98
0.04
3.2
2.3
—
—
—
0
0
53
543
0.98
0.04
1.2
1.2
—
—
—
0
0
20
210
0.95
0.03
12.7
12.7
846.9
827.1
nmol/l
0.06
20
202
32
330
0.97
0.03
1.6
1.6
—
—
—
0
0
15
158
0.95
0.02
2.1
1.5
—
—
—
0
0
58
590
0.98
0.02
3.0
3.1
—
—
—
0
0
23
222
1.04
0.02
1.0
1.1
3.0
11.5
iu/ml
—
6
61
81
819
0.99
0.01
1.6
1.9
3.4
4.5
iu/l
0.54
22
286
52
513
1.01
0.01
1.5
1.4
—
—
—
0
0
14
135
1.04
0.00
1.1
1.2
—
—
—
0
0
21
214
0.98
0.00
20.0
17.4
1416.1
1459.2
nmol/l
0.09
21
207
72
716
1.01
0.00
3.4
2.4
15.8
16.2
%
0.47
45
351
32
323
0.99
0.00
1.6
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
9
99
0.91
0.00
1.4
1.7
—
—
—
0
0
9
99
0.91
0.00
1.4
1.5
0.2
2.7
%
—
9
82
6
66
0.91
0.00
2.0
2.1
21.8
18.0
umol/l
—
6
66
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
3776.0
—
0
5
0
5
0.00
0.00
0.0
1.0
—
13.3
—
0
5

Mortality – FinRegistry

Association

Association between endpoint H8_PERFORATION and mortality.

Females

Parameter HR [95% CI] p-value
H8_PERFORATION 1.099 [0.99, 1.22] 0.071
Birth year 0.996 [0.99, 1.0] 0.37

During the follow-up period (1.1.1998 — 31.12.2019), 1840 out of 14921 females with H8_PERFORATION died.

Males

Parameter HR [95% CI] p-value
H8_PERFORATION 1.182 [1.07, 1.31] 0.001
Birth year 0.988 [0.98, 1.0] 0.01

During the follow-up period (1.1.1998 — 31.12.2019), 2140 out of 16352 males with H8_PERFORATION died.

Mortality risk

Mortality risk for people of age

years, who have H8_PERFORATION.

N-year risk Females Males
1 0.103% 0.211%
5 0.734% 1.322%
10 1.628% 3.392%
15 2.984% 6.549%
20 5.382% 11.176%

Relationships between endpoints

Index endpoint: H8_PERFORATION – Perforation of tympanic membrane

GWS hits: 4

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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