No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
823 |
4. Check minimum number of eventsNone |
823 |
5. Include endpointsNone |
823 |
6. Filter based on genotype QC (FinnGen only) |
823 |
Control definitions (FinnGen only)
- Control exclude
- ASTHMA_PNEUMONIA
Extra metadata
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Viral pneumonia (known virus, not influenza)
based on the number of shared cases.
Similar with more cases:
- Pneumonias (Asthma/COPD co-morbidities)
- COPD/asthma/ILD related pneumonia or pneumonia derived septicaemia
- COPD/asthma related pneumonia or pneumonia derived septicaemia
- COPD/asthma/ILD related infections
- COPD/asthma related infections
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7453 | 3529 | 3892 |
| Only index persons | 5766 | 2742 | 3024 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.10 | 0.11 |
| Only index persons | 0.11 | 0.10 | 0.12 |
| Median age at first event (years) | |||
| Whole population | 29.10 | 37.36 | 21.47 |
| Only index persons | 53.85 | 61.94 | 46.52 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 823 | 377 | 446 |
| Unadjusted period prevalence (%) | 0.17 | 0.13 | 0.20 |
| Median age at first event (years) | 66.78 | 63.74 | 69.35 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 663
- Matched controls
- 6630
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J12.1
ICD-10 Finland
Respiratory syncytial virus pneumonia
+∞
323.0
417
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
10.7
161.1
407
858
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.2
66.8
428
1989
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
8.2
66.0
160
246
J12.2
ICD-10 Finland
Parainfluenza virus pneumonia
+∞
52.8
50
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.5
50.7
213
627
J01MA14
ATC
moxifloxacin; systemic
7.1
49.6
131
222
C03CA01
ATC
furosemide; systemic
3.6
48.1
297
1217
WW200
NOMESCO Finland
Immunization
14.7
47.3
81
62
H02AB06
ATC
prednisolone; systemic
3.2
44.4
381
1960
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
7.0
43.5
115
193
R50.9
ICD-10 Finland
Fever, unspecified
4.3
43.3
186
548
4801A
ICD-9 Finland
Viral pneumonia, Pneumonia due to respiratory syncytial virus
+∞
43.2
41
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.1
42.3
149
357
R03AC02
ATC
salbutamol; inhalant
3.0
40.0
410
2315
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.9
38.4
138
335
127
Kela drug reimbursment
Transplant complication
18.4
37.9
59
35
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
7.9
37.4
89
127
J17.1*B25.0
ICD-10 Finland
Cytomegaloviral pneumonitis
+∞
36.8
35
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.2
35.6
102
189
J45.9
ICD-10 Finland
Asthma, unspecified
3.9
33.9
162
513
I50.9
ICD-10 Finland
Heart failure, unspecified
3.9
33.7
158
491
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
3.5
32.8
177
617
UGC12
NOMESCO Finland
Flexible bronchoscopy
5.3
32.8
107
231
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.6
32.7
173
594
R06.0
ICD-10 Finland
Dyspnoea
3.1
32.6
227
955
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
5.3
31.2
101
216
TGC00
NOMESCO Finland
Bronchial lavation
11.3
30.8
59
57
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.6
30.7
382
2270
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.7
30.6
153
499
B20.6
ICD-10 Finland
HIV disease resulting in Pneumocystis jirovecii pneumonia
+∞
29.4
28
*
J01MA12
ATC
levofloxacin; systemic
3.2
29.2
179
679
R03AK06
ATC
salmeterol and fluticasone; inhalant
3.8
29.1
137
423
TK800
NOMESCO Finland
Hemodialysis
10.8
28.8
56
56
L04AA06
ATC
mycophenolic acid; systemic
16.4
28.6
46
30
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
3.3
28.1
165
604
XW000
NOMESCO Finland
Bone marrow biopsy
6.4
27.4
75
130
L03AA02
ATC
filgrastim; parenteral
9.2
27.3
58
68
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
6.2
27.2
76
135
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
8.1
27.0
62
83
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.5
26.8
327
1868
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
6.9
25.8
66
104
H02AB04
ATC
methylprednisolone; systemic
3.5
25.4
133
445
J12.0
ICD-10 Finland
Adenoviral pneumonia
+∞
25.2
24
*
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
19.5
24.6
37
20
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
9.2
24.5
52
61
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
24.4
198
890
J20.5
ICD-10 Finland
Acute bronchitis due to respiratory syncytial virus
70.1
24.0
27
*
I50.0
ICD-10 Finland
Congestive heart failure
4.5
23.8
89
220
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.9
23.4
163
664
M04AA01
ATC
allopurinol; systemic
3.2
23.0
133
476
R03BB04
ATC
tiotropium bromide; inhalant
4.0
22.9
98
275
J46
ICD-10 Finland
Status asthmaticus
13.2
22.9
40
32
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
7.9
22.9
53
72
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
33.6
22.6
29
9
4800A
ICD-9 Finland
Viral pneumonia, Pneumonia due to adenovirus
+∞
22.0
21
*
B25.0
ICD-10 Finland
Cytomegaloviral pneumonitis
+∞
22.0
21
*
ZX108
NOMESCO Finland
Inhalation
26.1
21.9
30
12
Z94.0
ICD-10 Finland
Kidney transplant status
16.0
21.7
35
23
WX892
NOMESCO Finland
Monitored bed care
4.0
21.7
93
261
Z49.1
ICD-10 Finland
Extracorporeal dialysis
12.9
21.6
38
31
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
5.1
21.5
70
149
B23.8
ICD-10 Finland
HIV disease resulting in other specified conditions
113.6
20.7
22
*
J05AB11
ATC
valaciclovir; oral
3.2
20.7
119
422
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.3
20.6
240
1290
C90.0
ICD-10 Finland
Multiple myeloma
14.9
20.6
34
24
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.8
20.5
151
631
A28
ICPC
Limited function/disability NOS
2.9
20.5
145
591
L04AD01
ATC
ciclosporin; systemic
9.9
20.4
41
44
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
5.2
20.3
65
136
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.8
20.3
154
654
B03XA02
ATC
darbepoetin alfa; parenteral
9.1
19.9
42
49
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.4
19.7
74
183
A11CC03
ATC
alfacalcidol; systemic
7.5
19.7
47
67
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
7.2
19.6
48
71
Z2446
NOMESCO Finland
Social worker
3.8
19.4
88
259
JN4AD
NOMESCO Finland
Body CT examination
3.8
19.4
87
254
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.4
19.3
100
328
J45.1
ICD-10 Finland
Nonallergic asthma
4.6
19.2
68
159
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
21.6
18.7
27
13
A41.9
ICD-10 Finland
Sepsis, unspecified
5.7
18.6
54
101
XF400
NOMESCO Finland
ECG with 12 standard connections
2.7
18.4
147
641
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
7.1
18.3
45
67
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
4.2
18.1
72
188
ZX120
NOMESCO Finland
Intravenous
3.3
18.1
99
336
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
14.2
17.9
30
22
WX882
NOMESCO Finland
High dependency care
5.9
17.6
50
91
J01CA04
ATC
amoxicillin; systemic
2.4
17.5
549
4442
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.3
17.4
92
305
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
21.6
17.4
25
12
WW500
NOMESCO Finland
Blood transfusion
4.9
17.3
58
128
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
6.7
17.1
44
70
Z3231
NOMESCO Finland
Registered nurse
2.2
17.1
217
1195
JN4BD
NOMESCO Finland
Extensive body CT
3.1
17.1
104
380
B24
ICD-10 Finland
Unspecified human immunodeficiency virus [HIV] disease
51.4
17.1
20
*
153
Kela drug reimbursment
Lenalidomid
26.4
17.0
23
9
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.8
16.9
116
460
J45.0
ICD-10 Finland
Predominantly allergic asthma
3.8
16.7
73
208
R03BA05
ATC
fluticasone; inhalant
2.5
16.5
144
656
B23.1
ICD-10 Finland
HIV disease resulting in (persistent) generalized lymphadenopathy
23.8
16.5
23
10
GD1AD
NOMESCO Finland
Thorax CT examination
5.0
16.5
54
116
J01DB01
ATC
cefalexin; oral
2.2
16.5
535
4315
D64.9
ICD-10 Finland
Anaemia, unspecified
3.0
16.3
104
391
A02BC02
ATC
pantoprazole; systemic
2.0
16.2
412
2990
ZX112
NOMESCO Finland
Subcutaneous
7.8
16.1
37
50
L04AX04
ATC
lenalidomide; oral
25.2
16.1
22
9
N02AA05
ATC
oxycodone; systemic
2.6
16.1
128
552
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.7
16.0
117
482
B03XA01
ATC
erythropoietin; parenteral
15.0
15.9
26
18
B01AA03
ATC
warfarin; systemic
2.3
15.8
168
847
R02
ICPC
Shortness of breath/dyspnoea
2.9
15.8
101
381
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.0
15.8
65
176
J01MA02
ATC
ciprofloxacin; systemic
2.0
15.6
269
1672
N17.9
ICD-10 Finland
Acute renal failure, unspecified
5.3
15.5
48
97
J96.1
ICD-10 Finland
Chronic respiratory failure
8.3
15.5
34
43
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.3
15.4
175
906
J96.0
ICD-10 Finland
Acute respiratory failure
13.5
15.3
26
20
SPAT1254
SPAT
Administration of medicine
2.5
15.3
132
597
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
20.6
15.2
22
11
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.2
15.1
83
281
TPX10
NOMESCO Finland
Implantation of vascular injection port
5.8
14.9
42
76
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
25.7
14.8
20
8
A06AD11
ATC
lactulose; oral
2.6
14.7
120
523
A12AA04
ATC
calcium carbonate; oral
8.3
14.7
32
40
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
14.7
204
1154
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.0
14.6
87
314
H02AB09
ATC
hydrocortisone; systemic
6.3
14.4
38
63
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
7.0
14.4
35
52
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.9
14.3
60
165
V03AE02
ATC
sevelamer; oral
43.5
14.2
17
*
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
14.8
14.1
23
16
Z01.8
ICD-10 Finland
Other specified special examinations
2.2
14.1
161
832
V03AE01
ATC
polystyrene sulfonate; oral
10.4
14.1
27
27
SPAT1263
SPAT
Sampling
1.9
14.1
302
2015
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
7.0
13.9
34
51
AA1AD
NOMESCO Finland
CT of head and brain
2.1
13.9
178
968
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
8.2
13.7
30
38
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.1
13.7
54
141
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.7
13.6
97
392
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
26.4
13.4
18
7
J01FA06
ATC
roxithromycin; oral
1.9
13.4
255
1620
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.5
13.4
115
515
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
9.3
13.3
27
30
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
10.0
13.3
26
27
A46
ICD-10 Finland
Erysipelas
2.6
13.3
107
464
Z49.0
ICD-10 Finland
Preparatory care for dialysis
12.5
13.2
23
19
N18.0
ICD-10 Finland
End-stage renal disease
11.3
13.1
24
22
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
11.3
13.1
24
22
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.5
13.1
62
189
C07AB07
ATC
bisoprolol; oral
1.9
13.1
311
2135
WX725
NOMESCO Finland
Noninvasive ventilation
4.3
13.0
49
122
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
6.5
12.9
33
53
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
12.9
278
1842
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
5.6
12.9
37
69
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.1
12.8
173
959
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
14.4
12.8
21
15
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
5.0
12.8
41
87
R81
ICPC
Pneumonia
5.1
12.7
40
83
N02BE01
ATC
paracetamol; systemic, rectal
2.1
12.6
543
4554
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
32.7
12.6
16
5
R4110
NOMESCO Finland
Physiotherapy
2.0
12.6
190
1101
D70.82
ICD-10 Finland
Drug-induced neutropenia
11.3
12.6
23
21
137
Kela drug reimbursment
Uraemia requiring dialysis
11.3
12.6
23
21
R05
ICPC
Cough
2.1
12.6
157
841
A03
ICPC
Fever
2.3
12.6
129
632
S97
ICPC
Chronic ulcer skin
3.8
12.6
53
147
SPAT1255
SPAT
Intravenous administration of medicine
3.4
12.6
61
190
J17.1*B01.2
ICD-10 Finland
Varicella pneumonia
+∞
12.5
12
*
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.4
12.5
62
196
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
24.8
12.5
17
7
H02AB02
ATC
dexamethasone; systemic
2.7
12.3
87
349
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.8
12.3
80
306
C08CA01
ATC
amlodipine; oral
1.9
12.3
237
1505
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
38.3
12.2
15
*
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
7.2
12.2
29
42
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
16.2
12.2
19
12
R03BA02
ATC
budesonide; inhalant
2.3
12.0
117
558
H02AB07
ATC
prednisone; oral
2.5
12.0
102
453
L04AA01
ATC
[U] ciclosporin; systemic
7.8
12.0
27
36
TPH07
NOMESCO Finland
Cathetrisation of artery
2.6
12.0
93
392
N18.8
ICD-10 Finland
Other chronic renal failure
4.8
11.9
39
85
J01FF01
ATC
clindamycin; systemic
2.0
11.9
186
1089
R06.2
ICD-10 Finland
Wheezing
4.1
11.7
45
115
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.6
11.7
92
393
A04AA01
ATC
ondansetron; systemic, rectal
3.3
11.6
58
185
J05AB01
ATC
aciclovir; systemic
2.1
11.5
140
737
R96
ICPC
Asthma
3.0
11.5
66
232
J17.1
ICD-10 Finland
Pneumonia in viral diseases classified elsewhere
+∞
11.5
11
*
J20
ICD-10 Finland
Acute bronchitis
2.8
11.4
75
289
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.9
11.4
73
275
J45
ICD-10 Finland
Asthma
2.9
11.4
69
251
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
15.4
11.4
18
12
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.6
11.3
50
145
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
25.5
11.2
15
6
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
11.4
11.1
20
18
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.4
11.1
54
169
B01AB05
ATC
enoxaparin; parenteral
1.9
11.1
206
1279
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
10.3
11.1
21
21
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
44.1
10.9
13
*
R03AK07
ATC
formoterol and budesonide; inhalant
2.2
10.9
122
617
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
15.8
10.9
17
11
Z3226
NOMESCO Finland
Physiotherapist
2.1
10.8
139
748
A07AA02
ATC
nystatin; oral
3.2
10.8
57
190
WX872
NOMESCO Finland
Intensive care
3.5
10.8
50
151
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.8
10.7
225
1455
B02.9
ICD-10 Finland
Zoster without complication
3.3
10.7
54
174
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
3.1
10.7
58
197
J01AA02
ATC
doxycycline; systemic
1.8
10.7
469
3809
B97.4
ICD-10 Finland
Respiratory syncytial virus as the cause of diseases classified to other chapters
61.0
10.6
12
*
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
61.0
10.6
12
*
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
4.1
10.6
40
101
B05DA
ATC
Isotonic solutions
14.5
10.5
17
12
EBA15
NOMESCO Finland
Extraction of large number of teeth
4.2
10.5
39
97
B59
ICD-10 Finland
Pneumocystosis
+∞
10.4
10
*
M10.9
ICD-10 Finland
Gout, unspecified
3.3
10.4
52
166
ZXD05
NOMESCO Finland
Urgent procedure
1.8
10.3
216
1390
N06AX11
ATC
mirtazapine; oral
1.8
10.2
198
1241
XG410
NOMESCO Finland
Flow-volume spirometry
3.9
10.2
41
110
R53
ICD-10 Finland
Malaise and fatigue
2.0
10.1
143
796
AA1AA
NOMESCO Finland
Head X-ray examination
8.6
10.1
21
25
N02AX02
ATC
tramadol; systemic, rectal
1.7
10.1
263
1814
N05BA04
ATC
oxazepam; oral
1.9
10.0
162
952
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
7.8
10.0
22
29
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.0
9.9
58
208
L28
ICPC
Limited function/disability (L)
2.1
9.9
119
622
NJ3DA
NOMESCO Finland
Long bones of extremities X-ray examination
9.7
9.8
19
20
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.3
9.8
49
157
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
9.7
188
1178
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
5.2
9.7
29
58
WX730
NOMESCO Finland
Conventional respirator
6.5
9.6
24
38
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
5.8
9.6
26
46
R03DA04
ATC
theophylline; systemic, rectal
3.5
9.6
43
127
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
3.7
9.5
41
117
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
9.3
236
1602
TDM10
NOMESCO Finland
Puncture of maxillary antrum
4.3
9.3
33
79
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.0
9.3
130
721
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
7.4
9.3
21
29
N03AX16
ATC
pregabalin; oral
1.9
9.3
157
936
SPAT1301
SPAT
No procedures
1.7
9.2
221
1476
N19
ICD-10 Finland
Unspecified kidney failure
4.0
9.2
35
90
ZY010
NOMESCO Finland
Hospital outpatient
3.4
9.1
43
132
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.5
9.1
73
314
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
10.2
9.1
17
17
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
10.2
9.1
17
17
YNB10
NOMESCO Finland
Collection of stem cells for transplant
37.2
9.0
11
*
A04
ICPC
Weakness/tiredness general
2.2
9.0
99
495
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.2
9.0
91
441
TK810
NOMESCO Finland
Hemofiltration
24.4
8.9
12
5
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
8.9
219
1474
N30.0
ICD-10 Finland
Acute cystitis
2.2
8.8
92
452
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
3.4
8.7
41
126
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.9
8.6
51
184
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.1
8.6
107
567
R03DC03
ATC
montelukast; oral
2.1
8.6
98
497
WW300
NOMESCO Finland
Transfer of autologic stem cells
16.5
8.6
13
8
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
4.7
8.6
28
62
Z51.5
ICD-10 Finland
Palliative care
2.9
8.6
53
195
WX002
NOMESCO Finland
Sedation and analgesia
1.9
8.5
130
745
L04AX01
ATC
azathioprine; systemic
3.4
8.5
40
123
1CX01
NOMESCO Finland
NA
27.9
8.5
11
*
D70.89
ICD-10 Finland
Neutropenic splenomegaly
7.5
8.5
19
26
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.4
8.4
75
341
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
8.4
103
538
1XX32
NOMESCO Finland
NA
91.1
8.4
9
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
8.4
189
1232
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.9
8.4
147
883
H26.3
ICD-10 Finland
Drug-induced cataract
13.0
8.4
14
11
J18.1
ICD-10 Finland
Lobar pneumonia, unspecified
13.0
8.4
14
11
207
Kela drug reimbursment
Chronic arrhythmias
2.0
8.4
105
558
393
Kela drug reimbursment
Pomalidomide
+∞
8.3
8
*
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.6
8.3
62
255
B99
ICD-10 Finland
Other and unspecified infectious diseases
5.3
8.2
24
47
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
5.8
8.2
22
39
Z2221
NOMESCO Finland
Medical doctor
1.7
8.2
181
1172
J21.0
ICD-10 Finland
Acute bronchiolitis due to respiratory syncytial virus
8.3
8.1
17
21
V03AE03
ATC
lanthanum carbonate; oral
33.8
8.1
10
*
H05BX01
ATC
cinacalcet; oral
17.4
8.1
12
7
Z49.2
ICD-10 Finland
Other dialysis
10.2
8.1
15
15
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.9
8.0
32
86
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
5.6
8.0
22
40
K08.3
ICD-10 Finland
Retained dental root
2.8
8.0
51
193
ZXA00
NOMESCO Finland
Right side
1.7
8.0
174
1121
L03AA13
ATC
pegfilgrastim; parenteral
3.9
7.9
31
82
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
3.0
7.9
45
157
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
7.9
213
1456
B05DB
ATC
Hypertonic solutions
13.2
7.9
13
10
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
7.1
7.8
18
26
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.3
7.8
69
314
C03DA01
ATC
spironolactone; oral
2.2
7.7
78
378
3XA02
NOMESCO Finland
NA
45.5
7.7
9
*
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.7
7.7
52
203
N05CF01
ATC
zopiclone; oral
1.7
7.7
200
1354
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
8.2
7.6
16
20
SAA03
NOMESCO Finland
Extended examination of mouth
1.6
7.6
242
1730
WX722
NOMESCO Finland
PEEP
3.1
7.6
39
129
WX110
NOMESCO Finland
Local anesthesy
1.6
7.6
423
3483
EE1AA
NOMESCO Finland
X-ray of upper jaw or palate
25.3
7.6
10
*
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
9.0
7.6
15
17
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
5.9
7.6
20
35
WZC30
NOMESCO Finland
Teaching
2.1
7.6
89
459
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
10.2
7.6
14
14
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.4
7.5
35
108
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
5.1
7.5
22
44
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.4
7.4
63
279
A41.8
ICD-10 Finland
Other specified sepsis
6.1
7.4
19
32
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
13.5
7.4
12
9
XG466
NOMESCO Finland
Sleep oxymetry
3.6
7.4
31
88
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
3.4
7.4
34
104
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.3
7.4
26
63
J21.9
ICD-10 Finland
Acute bronchiolitis, unspecified
8.5
7.3
15
18
SPAT1257
SPAT
Teaching of medicine inhalation technique
4.0
7.3
28
73
L04AX06
ATC
pomalidomide; oral
+∞
7.3
7
*
1507
Kela drug reimbursment
Pomalidomide
+∞
7.3
7
*
J11.1
ICD-10 Finland
Influenza with other respiratory manifestations, virus not identified
6.3
7.3
18
29
JN3AD
NOMESCO Finland
Abdominal CT examination
2.5
7.3
57
244
321
Kela drug reimbursment
Paricalcitol and cinacalcet
15.9
7.2
11
7
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.3
7.2
35
111
C02AC05
ATC
moxonidine; oral
3.1
7.2
38
128
N03AX12
ATC
gabapentin; oral
2.0
7.2
100
548
WX726
NOMESCO Finland
High-flow oxygen therapy
30.3
7.2
9
*
Z94.2
ICD-10 Finland
Lung transplant status
30.3
7.2
9
*
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
30.3
7.2
9
*
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.6
7.2
268
1990
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
5.1
7.2
21
42
212
Kela drug reimbursment
Gout
5.4
7.1
20
38
SPAT1262
SPAT
Handing over of treatment supplies
1.8
7.1
127
766
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
8.9
7.1
14
16
R55
ICD-10 Finland
Syncope and collapse
2.1
7.1
77
384
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.7
7.0
46
178
SPAT1216
SPAT
Assessment of functional ability
1.9
7.0
102
570
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.2
7.0
35
114
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
6.4
7.0
17
27
SPAT1234
SPAT
Support of social functional capacity
2.8
6.9
42
156
K59.09
ICD-10 Finland
Constipation, unspecified
2.7
6.8
47
185
6BA02
NOMESCO Finland
NA
11.1
6.8
12
11
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
11.1
6.8
12
11
R60.0
ICD-10 Finland
Localized oedema
2.2
6.8
73
360
K65.0
ICD-10 Finland
Acute peritonitis
9.4
6.8
13
14
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.7
6.8
163
1074
329
Kela drug reimbursment
Lenalidomide
16.9
6.8
10
6
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.4
6.8
31
95
C01AA05
ATC
digoxin; systemic
2.3
6.7
61
279
B34.9
ICD-10 Finland
Viral infection, unspecified
3.5
6.7
29
85
WW402
NOMESCO Finland
Leucoferesis
22.8
6.7
9
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
6.7
263
1966
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
6.7
192
1327
A05AA02
ATC
ursodeoxycholic acid; oral
5.3
6.7
19
37
N05CD07
ATC
temazepam; oral
2.0
6.7
81
425
RS220
NOMESCO Finland
NA
5.6
6.6
18
33
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.1
6.6
76
387
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
8.8
6.6
13
15
R03BA01
ATC
beclometasone; inhalant
2.0
6.6
82
434
J02AC01
ATC
fluconazole; systemic
1.6
6.6
200
1402
J96.9
ICD-10 Finland
Respiratory failure, unspecified
10.2
6.6
12
12
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
10.2
6.6
12
12
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.4
6.5
52
224
H43.1
ICD-10 Finland
Vitreous haemorrhage
3.9
6.5
25
66
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
5.1
6.5
19
38
B01AB10
ATC
tinzaparin; parenteral
2.5
6.5
49
205
AN1
HP
Coronary angiography
2.0
6.5
82
437
B01AF02
ATC
apixaban; oral
2.1
6.5
71
356
NB6AA
NOMESCO Finland
Humerus X-ray examination
4.3
6.5
22
52
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.2
6.4
60
281
L04AX02
ATC
thalidomide; oral
70.5
6.4
7
*
ZXE00
NOMESCO Finland
One hour or less
1.6
6.4
246
1826
205
Kela drug reimbursment
Chronic hypertension
1.6
6.4
176
1201
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
5.0
6.4
19
39
N05AH04
ATC
quetiapine; oral
1.9
6.3
97
556
196
Kela drug reimbursment
Paricalcitol and cinacalcet
18.2
6.3
9
5
GD1RA
NOMESCO Finland
Dynamic X-ray examination of respiratory organs with convetional X-ray picture
18.2
6.3
9
5
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.5
6.3
45
185
SPAT1325
SPAT
Vaccination
1.6
6.3
225
1644
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.1
6.2
32
107
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.1
6.2
65
319
L01BB05
ATC
fludarabine; systemic
26.9
6.2
8
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.3
6.2
53
237
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.6
6.2
166
1122
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
6.4
6.2
15
24
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
5.8
6.2
16
28
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
4.1
6.1
22
55
J45.8
ICD-10 Finland
Mixed asthma
3.8
6.1
24
65
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
6.1
115
702
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
6.1
158
1063
C01DA14
ATC
isosorbide mononitrate; oral
1.8
6.1
105
625
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.7
6.0
142
928
J01DA01
ATC
[U] cefalexin; systemic
1.5
6.0
366
2996
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.9
6.0
89
501
L57.0
ICD-10 Finland
Actinic keratosis
2.1
6.0
64
319
Mortality – FinRegistry
↥Association
Association between endpoint VIRALPNEUMOKNOWN and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| VIRALPNEUMOKNOWN | 3.187 [2.11, 4.8] | < 0.001 |
| Birth year | 0.999 [0.99, 1.01] | 0.755 |
During the follow-up period (1.1.1998 — 31.12.2019), 411 out of 2247 females with VIRALPNEUMOKNOWN died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| VIRALPNEUMOKNOWN | 3.92 [2.56, 6.01] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 456 out of 2423 males with VIRALPNEUMOKNOWN died.
Mortality risk
Mortality risk for people of age
years, who have VIRALPNEUMOKNOWN.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.264% | 0.744% |
| 5 | 1.961% | 4.201% |
| 10 | 5.172% | 9.987% |
| 15 | 9.739% | 17.464% |
| 20 | 16.718% | 27.906% |
Relationships between endpoints
↥Index endpoint: VIRALPNEUMOKNOWN – Viral pneumonia (known virus, not influenza)
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data