COPD/asthma/ILD related infections

PULM_INFECTIONS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

167823

6. Filter based on genotype QC (FinnGen only)

167823

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2053597 887115 1149809
Only index persons 1568301 681421 886880
Unadjusted period prevalence (%)
Whole population 29.10 25.41 32.13
Only index persons 30.03 25.05 33.86
Median age at first event (years)
Whole population 30.48 42.53 20.63
Only index persons 29.05 40.23 20.46

-FinnGen-

Key figures

All Female Male
Number of individuals 167823 79855 87968
Unadjusted period prevalence (%) 33.28 27.22 38.78
Median age at first event (years) 43.38 43.23 43.51

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
21943
85491
1.41
323.01
3.8
3.1
2.3
2.4
mmol/l
31.60
19298
74753
2271
4436
2.62
317.36
3.9
2.8
8.3
8.7
kpa
15.95
2112
4135
12402
43385
1.52
315.05
1.8
1.7
1170.7
1165.2
nmol/l
0.25
9534
32685
3320
7798
2.19
313.43
1.3
1.2
—
—
—
0
0
27200
110392
1.38
312.45
2.5
2.1
75.8
897.0
nmol/l
0.50
24781
99972
11334
38939
1.55
312.06
3.3
2.6
3.3
3.0
e6/l
1.68
6324
20376
2458
5062
2.48
309.59
4.8
2.8
7.4
7.4
ph
1.47
2134
4196
16089
59584
1.46
308.54
5.4
3.8
—
—
—
0
0
5998
16214
1.93
307.65
4.3
2.8
4.7
4.6
kpa
2.36
5771
15753
26208
84193
1.89
307.65
7.3
5.2
—
—
—
0
0
3911
8961
2.25
307.65
4.8
2.9
—
—
—
0
0
33301
116252
1.82
307.65
7.6
5.3
0.6
0.7
%
48.71
31406
107994
20527
73404
1.56
307.65
2.4
1.9
217.3
200.8
u/l
0.90
19348
68765
19835
68028
1.64
307.65
3.6
2.8
0.4
0.4
e6/l
1.74
15451
49551
5639
12437
2.38
307.65
5.5
4.3
—
—
—
0
0
39497
149874
1.73
307.65
6.1
3.9
6.7
6.6
mmol/l
21.66
37304
137541
5621
12423
2.38
307.65
4.5
2.8
5.2
5.1
kpa
7.24
5235
11420
34311
121061
1.82
307.65
8.0
5.4
8.5
8.5
%
0.51
32483
113092
7244
18403
2.08
307.65
9.1
6.1
9.9
9.0
mmol/l
17.73
6941
17472
61632
282291
1.75
307.65
20.4
10.2
25.9
21.2
mg/l
178.43
53340
212128
7020
16600
2.24
307.65
3.2
2.2
10.2
10.8
g/l
17.81
6468
15112
2914
4786
3.14
307.65
1.2
1.1
—
—
—
0
0
25786
89801
1.69
307.65
4.2
2.9
59.9
61.4
ng/l
0.04
17180
55765
29782
118848
1.44
307.65
11.9
8.0
0.0
0.0
e9/l
0.94
24676
97195
11101
35912
1.65
307.65
2.5
1.9
30.0
29.6
s
6.16
10766
34873
11446
31601
1.97
307.65
2.3
1.8
—
—
—
0
0
12712
36239
1.92
307.65
4.1
2.9
0.8
0.8
mmol/l
16.53
11896
33772
9178
23096
2.14
307.65
8.3
6.5
1.4
0.7
mmol/l
42.55
7305
17983
940
691
6.89
307.65
1.2
1.1
—
—
—
0
0
48965
205069
1.64
307.65
9.5
6.3
79.0
76.7
u/l
19.54
46653
192354
2853
2217
6.67
307.65
1.4
1.1
—
—
—
0
0
1430
1388
5.24
307.65
1.6
1.3
—
—
—
0
0
1430
1387
5.25
307.65
1.6
1.3
—
—
—
0
0
8139
20761
2.09
307.65
8.8
6.9
95.1
96.3
%
50.74
7827
20000
27039
96478
1.65
307.65
10.0
7.3
1.2
1.2
inr
0.04
8345
27888
7458
19340
2.04
307.65
4.9
3.4
2.1
1.7
mmol/l
16.93
6127
15662
5523
12691
2.28
307.65
2.0
1.7
1.2
1.3
g/l
2.26
5034
11602
1638
1304
6.42
307.65
3.0
1.7
—
—
—
0
0
28990
107904
1.59
307.65
5.9
4.2
35.0
36.2
g/l
227.72
27055
99879
34563
123757
1.78
307.65
7.4
5.1
58.1
56.3
%
124.94
32676
115563
7061
18488
2.01
307.65
8.0
6.4
1.4
1.3
mmol/l
1.98
6762
17935
35877
130372
1.77
307.65
7.3
5.3
10.6
11.5
umol/l
29.98
34107
122974
6873
19593
1.84
307.65
4.7
3.8
0.9
0.9
%
0.15
2292
4513
2657
5080
2.68
307.65
1.4
1.2
—
—
—
0
0
3880
6140
3.29
307.65
2.1
1.8
2.0
2.4
ug/l
1.19
3471
5357
1430
1387
5.25
307.65
1.6
1.3
—
—
—
0
0
40424
151012
1.80
307.65
11.5
7.7
4.3
3.9
e9/l
154.98
36079
130854
37274
133802
1.84
307.65
7.7
5.3
0.2
0.2
e9/l
2.13
33421
116924
35099
125510
1.80
307.65
7.7
5.2
27.2
29.2
%
190.36
33123
116592
1430
1388
5.24
307.65
1.6
1.3
—
—
—
0
0
17793
62277
1.58
307.65
2.5
2.1
3.0
2.8
mg/l
14.28
15358
53058
7661
20194
2.01
307.65
4.9
3.4
7.4
7.4
ph
0.06
41
98
33363
123355
1.67
307.65
8.7
5.4
1.2
1.2
mmol/l
31.00
28402
103719
14084
44075
1.75
307.65
4.3
3.1
359.3
553.0
ng/l
4.29
10372
31989
6453
18840
1.79
307.65
4.7
3.8
0.1
0.1
%
1.23
2117
4190
4130
9919
2.15
307.65
5.3
3.8
24.4
24.0
mmol/l
10.63
3733
8901
6190
17302
1.87
307.65
3.1
2.2
65.7
67.1
g/l
33.55
5705
15710
18519
63766
1.62
307.65
8.6
5.9
—
—
—
0
0
30687
110687
1.69
307.65
7.8
4.9
1.2
1.2
mmol/l
50.42
28239
99661
47127
201795
1.51
307.65
5.0
3.6
13.4
10.6
mm/h
245.34
44120
186694
2417
4620
2.68
307.65
3.7
2.4
25.0
24.3
mmol/l
8.64
2121
4063
5553
12257
2.38
307.65
4.5
2.8
7.4
7.4
ph
0.45
768
1491
6740
17934
1.98
307.65
9.9
7.4
—
—
—
0
0
10901
34136
1.71
307.65
2.9
2.2
2.3
2.4
g/l
15.88
10096
31459
17586
53007
1.88
307.65
2.0
1.6
1.2
1.2
mg/l
0.05
13489
39709
7317
19715
1.96
307.65
9.5
7.2
121.2
121.7
g/l
1.32
7053
18992
17651
64220
1.50
307.65
4.8
3.4
90.5
91.9
%
10.61
17188
62597
3867
9028
2.21
307.65
1.7
1.4
12.7
14.0
u/ml
0.19
134
213
10294
28683
1.93
307.65
7.3
4.8
1.1
1.0
mmol/l
10.56
9656
26711
15772
49934
1.75
307.65
3.0
2.3
6.5
5.7
e6/l
7.80
14012
43033
9809
27538
1.91
307.65
2.0
1.6
—
—
—
0
0
9216
23054
2.15
307.65
8.3
6.6
5.1
5.1
kpa
5.08
8764
22089
2854
2219
6.67
307.65
1.4
1.1
—
—
—
0
0
10210
31377
1.74
307.65
3.0
2.3
21.7
23.6
%
28.65
8693
26818
8159
24645
1.74
307.65
3.0
2.3
1.8
1.7
%
18.58
7289
21769
8860
28440
1.64
307.65
1.7
1.3
—
—
—
0
0
44636
188068
1.51
307.65
5.2
3.8
—
—
—
0
0
4996
12663
2.05
307.65
8.4
6.0
24.8
24.4
mmol/l
13.05
4681
11741
36961
133487
1.81
307.65
7.4
5.1
1.9
1.9
e9/l
0.34
33265
117102
36095
128658
1.83
307.65
7.4
5.1
0.6
0.6
e9/l
96.34
31915
110755
14799
45976
1.77
307.65
3.2
2.4
534.9
553.5
mosm/kgh2o
14.13
12901
38497
9209
23043
2.15
307.65
8.3
6.6
11.5
13.5
kpa
184.96
8761
22070
21606
74236
1.66
307.65
3.7
2.8
74.6
87.7
e6/l
0.56
17188
55101
5859
15409
1.99
307.65
1.4
1.2
256.7
224.5
u/ml
0.76
5408
14233
34113
120407
1.81
307.65
7.7
5.2
2.8
2.9
%
25.22
32169
111820
21406
74105
1.64
307.65
3.4
2.7
—
—
—
0
0
2226
4072
2.79
307.65
4.2
2.8
—
—
—
0
0
9130
28791
1.68
307.65
24.1
22.2
1.3
1.3
inr
0.28
1333
4207
4319
10475
2.13
307.65
10.2
8.9
24.6
24.1
mmol/l
18.77
4004
9891
30068
122474
1.40
307.65
3.3
2.7
133.8
105.0
ug/l
25.27
28009
114096
43744
177011
1.63
307.65
5.3
3.8
1014.4
1529.2
e6/l
1.36
627
2249
7457
19442
2.03
307.65
4.9
3.4
5.9
5.8
kpa
12.05
7223
18946
6187
17306
1.87
307.65
3.3
2.4
219.0
171.7
ng/l
10.37
5617
15666
22901
78447
1.68
307.65
2.9
2.3
55.6
59.7
u/l
12.68
21285
72026
20393
72092
1.59
307.65
5.1
3.5
7.4
7.4
ph
3.94
4220
13026
23067
86265
1.50
307.65
3.7
2.9
34.5
32.6
u/l
1.07
21918
81766
18966
62460
1.71
307.65
3.5
2.6
1601.3
1103.1
ng/l
30.30
16285
52549
24048
51913
3.00
307.65
5.0
3.5
—
—
—
0
0
36228
129301
1.83
307.65
7.4
5.1
0.0
0.0
e9/l
1.49
32030
111229
6232
17879
1.82
307.65
4.4
3.6
0.7
0.6
%
0.36
1651
3284
8687
27724
1.65
307.65
3.1
2.5
7.7
8.5
umol/l
2.57
7412
24043
14699
52701
1.50
307.65
1.6
1.4
2.4
2.3
g/l
1.63
9362
31605
11720
37385
1.68
307.65
2.9
2.2
12.6
13.8
umol/l
53.66
10869
34598
5065
13108
2.01
307.65
8.0
6.7
25.0
24.6
mmol/l
10.85
5020
13010
24589
90009
1.57
307.65
4.3
3.2
89.4
96.2
e6/l
0.51
18309
60305
10715
35349
1.61
307.65
1.4
1.3
561.5
539.2
titre
0.50
2256
6992
9183
27974
1.74
307.65
8.7
6.2
104.1
104.7
mmol/l
22.26
8944
27457
7760
21804
1.88
307.65
2.3
2.1
360.6
382.7
nmol/l
15.21
7135
20115
19391
66618
1.63
307.65
3.6
2.7
—
—
—
0
0
3365
8054
2.15
303.32
5.0
3.0
25.0
24.6
mmol/l
11.76
3151
7402
2189
4315
2.59
300.42
4.9
2.9
8.5
8.9
kpa
10.74
2143
4221
2177
4289
2.59
299.07
4.9
2.9
5.0
5.0
kpa
3.67
2132
4195
1377
2058
3.40
299.04
3.1
2.0
—
—
—
0
0
2176
4288
2.59
298.80
4.9
2.9
2.6
2.3
mmol/l
3.64
1553
2710
31970
133989
1.36
294.14
4.2
3.2
0.0
0.0
estimate
0.13
6643
23972
21194
83124
1.40
293.28
2.8
2.1
—
—
—
0
0
11992
42245
1.51
292.07
3.1
2.5
1.3
1.1
e6/l
0.47
6953
23497
6070
18123
1.74
287.70
3.0
2.3
71.4
68.7
e9/l
5.74
4601
13530
31970
134489
1.35
282.72
5.6
4.4
0.0
0.0
estimate
0.10
6831
24567
6014
18028
1.73
280.75
4.8
3.8
0.1
0.3
%
4.04
1780
3587
32215
135951
1.34
276.60
4.2
3.3
0.0
0.0
estimate
0.10
6627
24016
1760
3250
2.76
272.36
3.3
2.3
—
—
—
0
0
3011
7196
2.14
271.76
1.7
1.5
327.5
256.0
titre
0.60
134
279
3653
9408
2.00
271.75
1.8
1.7
1.6
1.5
g/l
12.57
3162
8027
17362
66507
1.41
270.56
3.1
2.3
3452.1
4463.1
umol/l
2.79
15094
58085
5670
16886
1.74
270.23
1.5
1.4
—
—
—
0
0
1164
1667
3.54
268.27
2.4
2.3
1.2
1.2
e9/l
0.30
701
984
4220
11504
1.89
266.84
11.3
8.5
—
—
—
0
0
6034
18356
1.71
266.70
2.6
2.1
6.8
7.3
ug/l
0.68
5220
16066
2013
4063
2.52
263.45
2.9
2.1
16.3
16.8
%
6.23
1048
2078
6916
21903
1.64
262.97
2.4
2.2
0.2
0.2
g/l
11.96
6410
20444
4935
14286
1.78
258.26
2.9
2.0
—
—
—
0
0
1727
3287
2.67
252.81
1.5
1.6
0.7
0.8
g/l
2.44
1315
2455
1216
1875
3.29
252.18
1.4
1.3
2.8
3.1
g/l
7.31
882
1236
1215
1874
3.29
251.86
1.4
1.3
0.4
0.4
g/l
1.78
879
1240
1217
1880
3.28
251.69
1.4
1.3
—
—
—
0
0
4690
13470
1.80
251.60
10.9
8.2
0.7
0.7
%
0.03
4660
13401
1216
1878
3.28
251.58
1.4
1.3
6.5
7.0
g/l
2.80
886
1235
4704
13545
1.79
250.19
10.9
8.2
93.3
94.5
%
29.84
4683
13508
4693
13507
1.79
249.98
10.8
8.1
1.4
1.3
%
11.36
4660
13426
25244
103767
1.34
249.18
3.8
3.1
5.9
5.7
ph
0.41
15
77
2896
7086
2.09
246.00
2.5
2.1
509.1
510.4
ug/l
0.01
2698
6592
7005
22658
1.61
243.84
2.8
2.3
44.0
44.8
u/l
0.03
5967
19415
15177
57907
1.40
236.07
2.0
1.9
—
—
—
0
0
60681
285432
1.47
235.10
21.7
12.1
139.4
139.7
mmol/l
164.24
59458
277504
7427
24606
1.57
233.30
1.6
1.4
—
—
—
0
0
60815
286310
1.47
232.24
21.8
12.2
4.0
4.0
mmol/l
0.10
59489
277793
4487
13061
1.77
229.51
4.4
2.9
127.4
130.7
g/l
16.38
4379
12785
2457
5811
2.16
226.79
1.6
1.4
18.7
11.7
iu/ml
1.18
74
114
1543
2945
2.66
224.53
2.1
1.6
1.6
1.8
mmol/l
7.93
1512
2870
1561
3008
2.63
223.11
3.6
3.0
1.4
1.4
%
0.00
1238
2291
2782
6964
2.04
222.37
1.9
1.6
0.2
0.2
g/l
1.95
2647
6611
30188
128806
1.30
219.69
4.7
3.7
—
—
—
0
0
1196
2005
3.02
217.86
1.5
1.4
33.1
33.5
g/l
0.39
1085
1826
2834
7221
2.01
215.94
1.9
1.6
1.2
1.2
g/l
4.30
2701
6890
2798
7116
2.01
214.25
4.8
3.7
1.4
1.4
mmol/l
0.48
2739
7008
3573
9903
1.85
213.45
3.8
2.6
1.4
1.2
%
8.96
3557
9850
42273
189038
1.30
213.23
3.6
2.8
50.2
43.3
u/l
39.85
39731
177298
5466
17192
1.64
210.85
4.5
3.4
98.4
82.5
ng/l
18.09
4782
14840
25141
105026
1.31
210.78
2.1
1.9
95.3
97.1
pmol/l
6.65
13675
54360
9382
33373
1.47
210.24
1.7
1.6
—
—
—
0
0
2637
6609
2.04
209.90
7.0
4.6
1.3
1.3
mmol/l
0.94
2364
5777
16095
63037
1.36
209.12
2.7
2.1
—
—
—
0
0
3617
10143
1.83
208.19
4.3
2.9
25.4
25.1
mmol/l
4.55
3509
9848
2680
6779
2.02
208.12
1.4
1.3
—
—
—
0
0
3202
8694
1.88
203.39
6.2
4.1
1.7
1.6
%
3.50
2999
8158
14755
57266
1.37
201.72
1.6
1.5
19.9
20.7
nmol/l
8.39
12859
49080
914
1357
3.40
200.19
2.0
2.1
73.4
72.7
%
0.60
874
1308
1844
4077
2.30
198.80
2.8
2.7
33.9
34.1
umol/l
0.09
1574
3441
3469
9749
1.82
198.06
3.8
2.6
0.7
0.7
%
0.20
3344
9310
896
1336
3.39
195.04
2.0
2.1
13.3
14.4
%
1.18
443
631
3136
8575
1.87
194.83
6.3
4.1
0.9
0.9
%
0.47
2942
8038
848
1219
3.51
194.35
2.5
2.4
543.6
483.0
e6/l
2.11
704
1007
1267
2349
2.73
194.32
2.0
1.5
89.6
90.3
%
3.26
1246
2312
1077
1819
2.99
193.78
1.6
1.4
3434.7
2567.9
e6/l
0.57
805
1288
984
1591
3.13
189.78
2.2
2.1
40.7
43.3
%
0.83
120
229
24737
104192
1.29
188.57
4.4
3.4
—
—
—
0
0
9443
34280
1.44
188.41
2.5
2.3
138.0
126.7
ug/g
1.57
7463
26792
820
1182
3.50
187.22
2.6
2.5
0.2
0.2
e9/l
0.53
702
1009
3063
8420
1.86
187.08
6.0
4.1
—
—
—
0
0
2017
4780
2.15
184.80
2.4
1.9
129.1
131.9
g/l
4.46
1465
3516
1251
2379
2.66
183.12
7.0
5.6
11.7
11.3
mg/l
1.49
1135
2195
1924
4496
2.17
182.36
4.3
2.7
—
—
—
0
0
9533
34862
1.43
182.20
1.3
1.2
—
—
—
0
0
17716
71597
1.32
181.57
4.7
3.6
0.0
0.0
estimate
0.10
6536
23832
872
1341
3.28
181.46
1.4
1.1
1.0
0.7
u/ml
0.60
472
438
2364
6018
2.00
180.05
4.3
2.6
6.7
2.7
ratio
0.78
188
478
17712
71658
1.32
179.78
4.2
3.5
—
—
—
0
0
2415
6221
1.98
178.04
4.4
2.6
50.4
40.4
mg/l
0.97
1924
5095
4700
14831
1.63
177.68
1.3
1.2
—
—
—
0
0
12162
46577
1.37
177.20
1.3
1.3
34.2
35.0
iu/ml
0.15
3747
14568
2417
6240
1.97
177.08
4.4
2.6
58.6
63.7
mg/l
0.16
1933
5106
47742
219151
1.28
175.70
4.4
3.9
14.7
14.7
pmol/l
3.29
43916
199911
2536
6679
1.93
175.63
3.6
2.8
—
—
—
0
0
840
1293
3.28
174.57
2.7
2.4
728.6
686.0
e6/l
0.66
344
503
974
1654
2.98
173.68
1.5
1.4
49907.9
51447.5
e6/l
0.05
594
956
2618
7014
1.90
172.47
3.1
2.4
3.7
3.5
g/l
13.03
2495
6670
11493
43861
1.37
170.22
1.3
1.3
13.3
10.7
u/ml
1.74
4357
17542
1750
4052
2.19
169.45
1.3
1.2
200.9
98.9
titre
0.94
47
71
1881
4506
2.12
167.67
1.3
1.2
279.9
251.2
u/ml
3.29
1194
2889
736
1067
3.48
166.73
1.5
1.4
12.7
12.2
u/l
1.00
707
1041
17934
73343
1.30
165.42
3.8
2.8
—
—
—
0
0
1962
4824
2.07
163.68
1.5
1.4
—
—
—
0
0
3412
10090
1.73
163.66
2.0
1.9
38.3
40.0
u/l
4.78
3048
9028
915
1554
2.97
163.13
1.5
1.5
—
—
—
0
0
1681
3907
2.18
161.25
1.9
1.5
—
—
—
0
0
1063
1984
2.71
161.01
4.2
3.0
—
—
—
0
0
1942
4790
2.06
160.65
1.5
1.4
23.3
18.7
u/ml
0.59
50
79
702
1014
3.49
159.85
2.7
2.4
0.3
0.2
e9/l
0.43
681
988
2343
6254
1.91
155.82
5.2
3.9
3.9
3.9
mmol/l
0.19
2173
5933
849
1429
3.00
153.61
1.4
1.3
6.4
6.2
mmol/l
0.70
780
1342
5728
19557
1.51
153.22
4.6
3.2
1.2
1.2
mmol/l
11.88
5143
16797
907
1604
2.86
151.10
1.6
1.5
—
—
—
0
0
11589
45025
1.35
150.89
3.2
2.8
2.5
2.4
mmol/l
20.75
10034
39352
1445
3244
2.26
150.25
1.5
1.3
—
—
—
0
0
2300
6177
1.89
150.14
2.1
2.0
11.4
10.5
mg/l
2.82
2140
5796
2796
8052
1.77
146.48
2.9
1.8
7.5
7.3
g/l
6.29
2106
6026
2789
8027
1.77
146.40
2.9
1.9
3.8
3.8
g/l
0.24
2027
5716
12275
48338
1.33
145.22
1.7
1.6
—
—
—
0
0
817
1396
2.95
144.23
1.6
1.4
—
—
—
0
0
540
693
3.92
143.70
31.8
24.3
117.1
119.8
ug/l
0.28
444
584
15583
63508
1.29
143.51
1.3
1.3
1.6
1.7
u/ml
1.03
4151
17396
673
1030
3.29
141.10
1.3
1.3
14.6
12.3
u/l
1.33
617
964
1783
4482
2.02
140.15
1.5
1.4
117.3
108.8
u/ml
0.92
374
1044
1821
4622
2.00
139.45
8.2
5.5
11.2
11.2
mmol/l
0.41
1645
4157
1821
4623
2.00
139.36
8.3
5.5
104.7
105.5
mmol/l
7.71
1645
4159
13377
53599
1.31
139.11
1.7
1.6
37499318.0
36169692.0
pmol/l
0.08
11155
44712
1809
4601
1.99
137.74
1.7
1.5
—
—
—
0
0
2611
7518
1.77
136.70
2.9
1.9
10.1
10.2
g/l
0.59
2198
6274
279
193
7.26
134.15
1.7
1.4
—
—
—
0
0
2621
7598
1.76
134.09
3.0
1.9
3.2
3.0
g/l
13.10
2055
5900
2223
6168
1.83
131.17
4.5
3.3
1.6
1.4
mg/l
14.72
2062
5676
3253
10151
1.63
127.17
1.3
1.2
1.0
0.9
u/ml
0.21
286
872
1344
3144
2.16
126.81
5.6
4.8
366.6
371.2
umol/l
0.50
1177
2738
40957
187648
1.22
126.69
4.0
3.4
—
—
—
0
0
525
734
3.60
125.10
1.3
1.3
—
—
—
0
0
5964
21331
1.44
124.96
1.5
1.4
—
—
—
0
0
3011
9270
1.65
123.93
2.4
1.9
21.4
21.4
s
0.20
2630
7975
19132
81137
1.25
123.15
3.6
3.1
7.5
8.0
mmol/l
1.80
16143
68626
932
1889
2.49
120.59
3.6
3.0
59.7
57.0
%
2.16
622
1203
513
725
3.56
120.48
34.7
34.9
7.2
7.4
ug/l
0.94
469
662
55118
261224
1.26
119.71
5.2
4.5
2.2
2.0
mu/l
0.50
51160
240957
637
1050
3.06
119.26
2.7
2.7
39.1
40.9
%
0.84
231
341
497
693
3.61
118.88
2.1
2.3
10.6
10.1
%
0.26
461
647
1369
3321
2.09
118.00
3.2
3.0
0.8
0.8
nmol/l
1.32
1029
2553
2586
7755
1.70
117.24
2.7
2.1
92.7
92.4
%
0.19
2429
7141
1390
3413
2.06
116.14
1.2
1.2
—
—
—
0
0
1674
4412
1.92
115.20
4.3
3.2
—
—
—
0
0
15096
62772
1.26
113.43
4.0
3.3
—
—
—
0
0
332
346
4.82
111.95
2.5
1.8
—
—
—
0
0
414
527
3.95
111.40
1.2
1.1
—
—
—
0
0
2295
6759
1.72
110.89
1.4
1.4
275.4
279.6
ug/g
0.38
1301
3881
6146
22581
1.40
110.03
4.7
3.4
—
—
—
0
0
478
686
3.51
109.96
2.0
2.1
29.1
28.5
%
0.36
451
654
5066
18059
1.44
107.23
3.1
2.5
4.3
4.0
e9/l
12.12
3932
14180
14175
58875
1.26
106.39
4.6
3.6
1.0
1.0
kg/l
0.36
2324
8532
2145
6300
1.73
104.58
2.8
1.9
37.0
38.4
g/l
17.84
1887
5376
151
55
13.77
104.07
1.9
1.5
45.3
44.9
umol/l
0.03
151
55
1147
2761
2.10
100.82
1.6
1.3
—
—
—
0
0
1292
3256
2.01
100.74
1.8
1.5
—
—
—
0
0
254
224
5.69
100.57
2.3
2.2
—
—
—
0
0
62372
301562
1.31
99.77
21.6
12.5
77.0
74.8
umol/l
40.99
62353
301403
1440
3791
1.92
99.37
1.1
1.1
8.2
11.9
au/ml
1.40
68
278
1348
3483
1.96
98.12
1.5
1.4
62.9
64.0
mmol/l
0.38
1070
2759
694
1357
2.58
96.44
17.6
18.8
1476.8
3188.3
nmol/l
0.70
663
1299
3691
12620
1.49
96.29
3.1
2.5
0.3
0.3
e6/l
0.13
3594
12241
7721
29999
1.32
95.99
1.5
1.4
—
—
—
0
0
377
504
3.76
95.44
2.0
2.2
468.4
838.7
e6/l
0.31
209
253
6416
24267
1.36
95.41
5.3
3.5
—
—
—
0
0
61864
299048
1.30
95.22
17.7
10.3
—
—
—
0
0
17124
73419
1.22
93.83
3.6
3.2
529.4
368.8
mg/l
3.55
11348
45455
17929
77273
1.22
93.13
4.4
3.9
12.7
7.9
mg/mmol
16.85
11684
48264
661
1292
2.58
91.94
12.6
13.5
830.3
1576.4
nmol/l
0.48
634
1249
445
698
3.21
90.12
2.0
2.0
8.4
8.4
%
0.01
432
681
4750
17273
1.40
89.34
3.3
3.4
4.4
4.5
pmol/l
8.65
4213
15459
588
1097
2.70
89.27
2.4
2.4
1091.8
934.7
u/ml
0.55
583
1087
25136
112212
1.19
88.35
2.1
2.0
—
—
—
0
0
3680
12798
1.46
88.02
2.5
2.2
5950.8
6061.3
u/l
0.07
1397
5175
433
685
3.18
86.58
2.0
2.0
—
—
—
0
0
532
965
2.77
84.98
3.0
2.3
7.4
7.4
ph
0.80
176
330
5427
20365
1.36
84.28
4.0
3.2
—
—
—
0
0
717
1537
2.35
82.67
2.2
1.6
4.3
3.4
mg/l
4.80
676
1474
6393
24668
1.33
82.51
3.9
4.0
17.4
25.8
ug/l
1.67
5144
19489
1115
2878
1.95
81.41
1.6
1.5
—
—
—
0
0
2173
6870
1.60
80.05
1.3
1.2
889.7
950.9
titre
0.16
64
206
1988
6180
1.63
78.34
1.4
1.3
548.0
516.4
mg/l
0.61
1875
5914
361
542
3.35
78.08
1.7
1.2
—
—
—
0
0
2186
6980
1.59
77.28
1.3
1.2
113.6
134.1
titre
0.57
211
600
1988
6230
1.62
75.86
1.4
1.3
—
—
—
0
0
7421
29594
1.29
74.72
1.4
1.3
—
—
—
0
0
772
1790
2.17
74.50
1.2
1.2
232.7
132.5
titre
0.64
33
40
774
1797
2.17
74.45
1.2
1.2
190.1
188.5
titre
0.02
130
307
50409
240031
1.18
74.14
23.0
13.1
13.8
13.5
%
151.85
49609
234672
5698
21949
1.33
73.95
1.4
1.4
—
—
—
0
0
2477
8230
1.53
73.58
3.7
3.0
0.4
0.3
g/l
1.92
1211
3418
2283
7489
1.54
71.82
1.2
1.1
—
—
—
0
0
371
601
3.10
71.63
5.0
5.0
—
—
—
0
0
904
2267
2.01
71.50
1.1
1.1
—
—
—
0
0
2276
7469
1.54
71.48
1.2
1.1
—
—
—
0
0
950
2429
1.97
71.26
16.0
4.6
7.5
7.2
mmol/l
0.86
809
1941
1763
5446
1.64
71.19
1.3
1.3
3.8
3.7
mmol/l
2.73
1643
5143
940
2420
1.96
69.18
2.0
1.9
25.2
24.6
ug/l
0.06
919
2371
446
824
2.72
69.06
2.3
1.9
—
—
—
0
0
426
773
2.77
68.13
2.3
2.1
—
—
—
0
0
840
2109
2.01
66.26
1.5
1.5
—
—
—
0
0
1744
5478
1.61
65.90
1.5
1.4
1323.5
2413.0
e6/l
0.64
1437
4395
292
426
3.44
65.90
1.3
1.3
3.5
3.5
mmol/l
0.09
267
398
570
1222
2.35
65.82
4.3
3.3
—
—
—
0
0
1739
5476
1.60
65.05
1.5
1.4
47.3
26.3
e6/l
1.03
1353
4189
1649
5134
1.62
64.55
1.5
1.4
—
—
—
0
0
865
2226
1.96
63.77
1.4
1.3
—
—
—
0
0
127
86
7.41
62.25
1.1
1.2
—
—
—
0
0
1288
3792
1.71
62.18
4.4
2.9
64.1
65.0
%
0.74
1283
3779
4438
16892
1.34
62.04
3.2
2.6
—
—
—
0
0
2166
7252
1.51
62.01
1.3
1.3
39.9
34.2
u/ml
0.40
132
433
832
2133
1.96
62.00
1.5
1.6
279.8
280.5
mosm/kgh2o
0.32
635
1657
1647
5194
1.60
61.23
3.4
2.7
—
—
—
0
0
62334
303870
1.24
61.10
12.8
8.8
26.9
26.1
u/l
8.60
60602
293049
2676
9401
1.44
60.29
1.7
1.7
—
—
—
0
0
1036
2886
1.81
60.26
2.5
2.5
—
—
—
0
0
800
2044
1.97
60.20
2.5
1.7
—
—
—
0
0
975
2674
1.84
59.58
1.2
1.2
—
—
—
0
0
1355
4095
1.67
59.48
1.1
1.1
—
—
—
0
0
4412
16880
1.33
59.46
1.3
1.3
41.2
53.4
au/ml
2.07
138
735
137
109
6.30
59.42
1.1
1.1
—
—
—
0
0
119
79
7.55
59.16
1.1
1.1
—
—
—
0
0
756
1908
1.99
58.85
2.7
2.4
0.1
0.7
g
—
5
13
461
943
2.46
58.81
2.3
2.1
143.7
136.0
umol/l
0.15
233
496
315
526
3.01
58.07
1.4
1.4
58.2
66.3
%
3.07
269
436
1997
6665
1.51
58.01
1.3
1.3
8.0
9.5
u/ml
0.45
319
1018
333
579
2.89
57.44
3.7
3.0
53.0
51.6
%
0.45
322
557
1366
4176
1.65
57.42
1.1
1.1
—
—
—
0
0
4760
18517
1.31
56.94
2.4
2.4
19.3
24.2
au/ml
2.51
238
1204
1965
6570
1.51
56.60
1.3
1.3
4.7
6.8
u/ml
0.81
216
667
1870
6188
1.53
56.49
1.5
1.4
—
—
—
0
0
1362
4181
1.64
56.36
1.1
1.1
—
—
—
0
0
1363
4187
1.64
56.25
1.6
1.5
—
—
—
0
0
1356
4168
1.64
55.83
1.1
1.1
—
—
—
0
0
1626
5232
1.57
55.58
1.2
1.2
14.0
16.9
u/ml
0.14
24
74
1408
4400
1.61
54.32
3.8
2.7
—
—
—
0
0
1718
5636
1.54
53.97
1.8
1.6
15688.1
12044.2
e6/l
1.62
1270
4064
468
1005
2.34
53.96
1.2
1.1
4.1
3.9
iu/ml
0.15
28
80
743
1924
1.94
53.90
1.5
1.4
1.4
1.4
promille
0.28
542
1499
348
649
2.69
53.13
1.0
1.0
—
—
—
0
0
80
33
12.15
52.30
1.1
1.0
—
—
—
0
0
5654
22744
1.27
51.91
1.2
1.2
—
—
—
0
0
1224
3737
1.65
51.74
2.0
2.0
2.6
8.0
titre
2.35
25
108
459
999
2.31
51.42
1.8
1.4
—
—
—
0
0
229
336
3.42
51.41
1.4
1.4
23.7
19.3
%
1.32
196
293
339
636
2.68
51.21
1.1
1.1
—
—
—
0
0
52483
252890
1.15
51.16
6.0
5.2
40.0
38.9
mmol/mol
91.83
48797
235133
1265
3909
1.63
51.04
1.3
1.2
4.1
3.9
u/ml
0.27
549
1719
684
1757
1.96
50.80
2.0
1.9
1.4
0.8
g/24h
0.90
44
100
258
414
3.13
50.74
1.3
1.3
130.7
442.7
ug/l
1.70
147
208
388
785
2.48
50.71
2.6
2.9
—
—
—
0
0
1619
5333
1.53
49.94
1.3
1.2
5.1
6.2
u/ml
0.23
129
392
692
1799
1.94
49.69
1.3
1.2
2.1
2.0
mmol/l
1.01
639
1673
388
793
2.46
49.69
1.7
1.6
—
—
—
0
0
429
927
2.33
48.86
2.0
1.7
1.9
2.0
umol/l
0.51
402
864
779
2120
1.85
48.85
1.2
1.1
—
—
—
0
0
878
2485
1.78
48.59
1.3
1.2
59.2
66.0
u/l
1.24
622
1623
196
269
3.66
48.25
1.3
1.4
147.4
61.1
ng/l
1.40
133
145
227
348
3.27
47.87
1.9
1.7
—
—
—
0
0
1084
3288
1.66
47.01
1.1
1.1
1.5
1.5
g/l
2.54
989
2966
2398
8637
1.40
46.99
3.9
2.6
—
—
—
0
0
406
879
2.32
46.09
2.6
2.2
8.7
9.5
mmol/l
3.47
300
636
1630
5485
1.50
45.55
1.3
1.2
42.1
43.1
u/ml
0.08
187
496
360
741
2.44
45.50
2.4
1.9
59.7
62.5
ug/l
0.26
352
721
278
504
2.77
44.76
2.1
1.8
37.2
34.1
u/l
0.11
261
444
2681
9940
1.36
44.15
2.7
2.0
—
—
—
0
0
1116
3472
1.62
43.90
1.3
1.3
47.1
28.2
u/l
3.49
975
3034
3102
11772
1.33
43.88
1.9
1.8
—
—
—
0
0
95
70
6.80
43.88
1.1
1.1
—
—
—
0
0
920
2724
1.70
43.64
1.7
1.5
39.1
31.2
iu/ml
0.53
48
121
97
75
6.48
43.16
1.1
1.1
—
—
—
0
0
530
1331
2.00
42.00
1.5
1.4
5.8
6.0
u/l
0.13
442
1113
650
1756
1.86
41.78
1.2
1.1
—
—
—
0
0
1494
5029
1.50
41.71
1.4
1.3
—
—
—
0
0
823
2393
1.73
41.65
4.0
2.9
—
—
—
0
0
1134
3589
1.59
41.63
1.5
1.4
—
—
—
0
0
1667
5742
1.46
41.55
1.1
1.1
1.7
1.7
u/ml
0.06
719
2250
54999
267011
1.14
40.65
20.1
11.7
39.6
40.0
%
19.69
40222
200890
2713
10207
1.34
40.63
1.7
1.6
—
—
—
0
0
200
319
3.15
39.84
1.4
1.2
—
—
—
0
0
254
469
2.72
39.65
1.4
1.4
2.5
2.7
%
0.19
221
395
1425
4809
1.49
39.31
1.1
1.1
2.3
2.1
u/ml
0.26
392
1158
698
1969
1.78
39.17
1.2
1.2
—
—
—
0
0
590
1579
1.88
39.05
1.1
1.1
9.7
7.7
iu/ml
0.82
132
437
1207
3948
1.54
38.50
1.2
1.2
—
—
—
0
0
607
1660
1.84
37.64
1.1
1.1
—
—
—
0
0
544
1435
1.91
37.61
1.2
1.2
—
—
—
0
0
2951
11374
1.31
37.39
1.1
1.1
12.4
6.7
u/ml
0.37
56
166
481
1220
1.98
37.17
2.6
2.1
—
—
—
0
0
3116
12111
1.30
37.14
2.6
1.9
—
—
—
0
0
2615
9919
1.33
37.06
1.1
1.1
—
—
—
0
0
306
645
2.38
36.93
7.4
5.6
24.7
25.1
mmol/l
0.69
280
588
128
156
4.11
36.69
1.3
1.3
28.0
17.1
%
2.46
106
117
1162
3819
1.53
36.30
1.1
1.1
118.3
118.3
%
0.01
1062
3438
878
2699
1.64
36.29
2.3
2.3
—
—
—
0
0
858
2623
1.65
36.23
2.8
2.0
4.1
4.0
mmol/l
0.38
853
2603
302
639
2.37
36.17
1.2
1.1
—
—
—
0
0
1499
5198
1.45
36.14
1.1
1.1
5.6
5.6
u/ml
0.02
809
2615
5480
32728
0.82
36.10
1.3
1.3
—
—
—
0
0
857
2623
1.64
36.03
2.8
2.0
105.4
105.9
mmol/l
2.22
852
2602
217
388
2.81
35.92
1.2
1.0
—
—
—
0
0
217
389
2.80
35.77
1.2
1.0
—
—
—
0
0
931
2916
1.61
35.74
1.7
1.5
56.6
55.1
%
0.45
600
1830
367
853
2.16
35.54
2.1
1.6
—
—
—
0
0
2305
8639
1.35
35.38
1.4
1.4
10.4
10.0
u/l
0.71
1901
7032
386
918
2.11
35.34
1.4
1.2
—
—
—
0
0
216
389
2.79
35.32
1.2
1.0
—
—
—
0
0
967
3070
1.59
35.12
1.3
1.3
—
—
—
0
0
1100
3602
1.54
34.95
1.1
1.2
—
—
—
0
0
1429
4942
1.46
34.94
1.1
1.1
1.3
1.1
u/ml
0.37
640
2041
420
1038
2.03
34.85
2.3
2.2
65.7
267.1
ug/l
1.06
404
983
392
944
2.09
34.79
3.0
2.7
—
—
—
0
0
230
433
2.66
34.74
1.3
1.4
25.5
18.0
%
3.03
211
388
430
1075
2.01
34.61
1.1
1.1
—
—
—
0
0
8182
35481
1.17
34.47
1.3
1.3
—
—
—
0
0
3316
13139
1.28
34.03
2.4
2.4
—
—
—
0
0
1419
4928
1.45
33.96
4.1
2.6
1.6
1.6
mmol/l
0.38
1388
4833
837
2588
1.63
33.86
2.9
2.0
—
—
—
0
0
71
51
6.98
33.51
1.4
1.1
—
—
—
0
0
2560
9825
1.32
33.42
1.3
1.3
219.6
227.3
miu/ml
0.47
1159
4695
888
2796
1.60
33.40
2.3
2.0
32.4
32.8
pg
2.26
876
2777
3295
13087
1.27
33.16
2.6
1.9
—
—
—
0
0
3319
13217
1.27
32.69
2.6
1.9
—
—
—
0
0
1217
4134
1.48
32.59
1.1
1.0
5.4
4.0
u/ml
1.24
523
1570
3444
13787
1.26
32.47
1.1
1.1
271.4
193.8
titre
0.63
74
391
3309
13186
1.27
32.41
2.5
1.9
—
—
—
0
0
571
1607
1.79
32.40
1.1
1.1
—
—
—
0
0
100
110
4.56
32.23
3.8
3.4
2.2
2.2
mg/l
0.02
84
99
471
1252
1.89
31.94
1.2
1.2
282.5
343.1
u/l
0.54
433
1175
124
170
3.66
30.77
1.7
1.5
—
—
—
0
0
166
278
2.99
30.76
2.3
3.2
15.0
14.7
ml/dl
0.71
154
261
605
1762
1.73
30.61
1.1
1.1
—
—
—
0
0
1063
3562
1.50
30.44
1.3
1.3
0.2
0.3
nmol/l
0.15
70
206
1063
3579
1.49
29.77
1.3
1.3
1.7
1.1
nmol/l
0.21
1015
3456
444
1186
1.88
29.72
1.1
1.1
10.0
9.2
u/ml
0.13
86
192
124
175
3.55
29.63
1.3
1.3
104.9
215.8
u/l
0.29
91
134
986
3271
1.52
29.61
1.3
1.2
54.2
53.4
u/ml
0.03
70
205
168
291
2.90
29.48
1.2
1.2
1.7
1.8
mmol/l
0.27
120
159
533
1514
1.77
29.39
12.8
11.3
0.6
0.6
mmol/l
0.72
492
1396
3233
13000
1.26
29.32
2.5
1.9
—
—
—
0
0
972
3224
1.52
29.22
1.3
1.3
—
—
—
0
0
1822
6784
1.35
29.21
1.9
1.9
9.1
13.0
iu/l
0.26
641
2575
1694
6240
1.37
29.07
1.3
1.2
—
—
—
0
0
1130
3872
1.47
29.04
1.1
1.0
5.9
5.0
u/ml
0.49
498
1574
2851
11307
1.27
29.00
1.6
1.6
312.3
309.3
mu/l
0.15
2551
10188
1322
4669
1.43
28.99
4.2
2.6
7.7
7.5
mmol/l
1.71
1296
4588
1703
6284
1.37
28.91
1.2
1.2
—
—
—
0
0
2911
11589
1.27
28.71
1.2
1.2
—
—
—
0
0
492
1377
1.79
28.51
1.3
1.2
33.9
34.9
mmol/l
0.42
415
1207
846
2741
1.55
28.28
1.5
1.4
—
—
—
0
0
984
3307
1.50
27.83
1.1
1.0
0.7
0.3
u/ml
0.97
245
640
593
1766
1.69
27.77
2.8
2.1
—
—
—
0
0
641
1956
1.65
27.41
1.2
1.1
—
—
—
0
0
1243
4389
1.43
27.32
1.5
1.4
—
—
—
0
0
182
346
2.64
27.14
2.4
2.0
1.2
1.2
mmol/l
0.19
175
330
115
164
3.51
27.13
1.4
1.3
71.7
76.5
%
0.74
94
144
133
211
3.16
26.91
1.5
1.3
71.5
88.7
u/ml
—
7
10
965
3263
1.49
26.53
1.8
1.7
1349.7
5407.4
titre
2.96
31
135
115
170
3.39
25.83
3.4
2.5
1.3
1.4
mg/l
0.17
81
116
161
296
2.73
25.56
5.5
4.5
44.4
47.6
ug/min
0.22
132
224
2179
8491
1.29
25.46
3.4
3.5
977.1
2315.0
u/ml
0.90
1868
7266
58
46
6.32
25.43
1.5
1.1
—
—
—
0
0
833
2769
1.51
24.88
1.1
1.1
29.7
23.5
au/ml
—
7
16
351
921
1.91
24.87
1.1
1.2
—
—
—
0
0
1271
4590
1.39
24.64
1.3
1.3
26.1
26.2
u/l
0.03
1029
3807
55390
270969
1.11
24.62
4.6
4.2
5.9
5.8
mmol/l
60.29
50910
249202
781
2568
1.53
24.53
1.7
1.5
—
—
—
0
0
1184
4227
1.41
24.53
2.1
2.2
6.8
6.7
umol/l
0.04
872
3068
3254
19716
0.82
24.49
1.4
1.4
—
—
—
0
0
475
1379
1.73
24.44
1.4
1.5
6.9
7.8
ug/l
0.56
422
1256
814
2709
1.51
24.19
1.1
1.1
33.2
81.4
au/ml
—
9
30
3077
12579
1.23
24.05
3.8
3.1
—
—
—
0
0
1564
5870
1.34
23.87
2.6
2.3
130.3
101.2
ug/min
1.31
960
3467
998
3476
1.44
23.68
1.6
1.5
59.3
63.7
mu/l
0.32
891
3121
4791
20478
1.18
23.55
1.2
1.2
133.5
146.4
iu/ml
1.17
1698
7946
96
134
3.59
23.39
1.2
1.1
10.9
8.0
mg/l
1.22
90
122
871
2968
1.48
23.13
2.4
1.8
25.0
26.3
mg/l
0.27
265
736
368
1006
1.84
23.10
2.5
2.4
56.1
53.3
umol/l
0.90
310
839
171
347
2.47
22.58
2.8
2.3
62.3
40.6
mg/l
0.45
24
58
670
2173
1.55
22.43
2.1
2.2
19.2
19.4
nmol/l
0.17
625
2075
314
827
1.91
22.09
1.2
1.2
—
—
—
0
0
718
2380
1.52
21.80
4.4
3.6
49.1
47.5
u/ml
0.07
711
2348
233
554
2.11
21.61
2.2
1.6
—
—
—
0
0
1346
5023
1.35
21.38
2.4
1.9
0.9
0.8
nmol/l
6.25
1098
4248
537
1672
1.61
21.37
1.6
1.4
69.0
69.9
umol/l
0.14
41
142
1532
5833
1.32
21.25
2.2
2.0
—
—
—
0
0
74
91
4.07
21.19
2.0
1.6
173.7
184.0
ug/g
0.14
60
79
128
231
2.78
21.10
1.3
1.2
1.0
2.0
mmol/l
0.98
89
145
1013
3618
1.41
21.02
1.6
1.6
—
—
—
0
0
121
212
2.86
20.99
1.4
1.1
—
—
—
0
0
676
2232
1.52
20.93
1.5
1.3
111100.3
103926.7
e6/l
0.10
468
1522
421
1237
1.71
20.86
1.6
1.4
24.4
26.7
umol/l
0.77
397
1175
328
896
1.84
20.71
1.3
1.2
0.3
0.3
g/l
0.44
269
695
345
959
1.81
20.62
5.4
3.6
2087.3
2281.6
mg/l
0.06
272
648
673
2236
1.51
20.26
1.6
1.5
29.6
33.3
%
1.62
407
1409
402
1177
1.71
20.19
2.1
2.1
1918.2
2012.4
ml
0.90
358
1056
193
437
2.21
20.17
1.3
1.2
—
—
—
0
0
608
1980
1.54
20.06
1.2
1.2
42.2
51.9
u/ml
0.33
33
81
525
1653
1.59
20.00
1.2
1.1
1.1
1.1
ratio
0.83
187
593
214
508
2.11
19.97
1.1
1.2
142.2
637.3
titre
—
9
30
548
1745
1.58
19.93
3.3
3.1
28.2
27.0
mu/l
0.30
521
1629
1281
4797
1.34
19.92
3.5
3.3
467.1
987.0
u/ml
1.53
1158
4352
466
1427
1.64
19.84
1.1
1.1
3.0
5.6
nmol/l
0.86
102
265
407
1204
1.70
19.72
2.5
2.1
33.4
32.8
umol/l
0.02
50
102
593
1932
1.54
19.54
1.1
1.1
—
—
—
0
0
310
848
1.83
19.53
2.5
2.3
148.7
153.6
nmol/l
0.29
266
731
639
2120
1.51
19.40
1.5
1.3
1.5
1.4
nmol/l
1.17
581
1918
919
3274
1.41
19.38
1.4
1.4
301.0
305.4
pmol/l
0.10
707
2558
622
2057
1.52
19.17
1.2
1.1
49.9
66.3
u/ml
—
8
27
410
1226
1.68
19.12
1.3
1.2
61.3
69.0
%
0.84
56
125
2189
8845
1.25
19.06
2.5
2.7
—
—
—
0
0
3594
15262
1.19
18.99
1.4
1.3
26.4
27.5
iu/l
1.27
3095
13123
448
1375
1.64
18.94
1.3
1.3
180.6
473.7
titre
1.75
32
93
212
513
2.07
18.89
1.8
1.6
0.8
0.2
mmol/l
1.33
195
492
951
3444
1.39
18.28
2.7
2.7
155.8
1024.4
u/ml
1.71
903
3259
217
538
2.02
18.17
1.3
1.2
—
—
—
0
0
345
999
1.73
18.08
2.2
1.6
27.7
29.6
umol/l
2.88
330
964
420
1284
1.64
18.06
1.5
1.7
1.3
1.2
nmol/l
0.15
327
1020
7650
34463
1.12
17.87
1.7
1.7
—
—
—
0
0
432
1335
1.62
17.82
1.3
1.3
63.8
71.6
titre
0.20
34
121
118
227
2.61
17.42
1.5
1.5
122.9
110.3
ug/l
0.53
97
185
120
233
2.58
17.41
1.4
1.4
12.2
11.1
%
0.17
64
118
552
1818
1.52
17.40
1.4
1.3
—
—
—
0
0
224
572
1.96
17.35
1.2
1.1
—
—
—
0
0
119
231
2.58
17.27
4.3
2.6
36.7
43.4
umol/l
2.31
102
197
71
100
3.56
17.21
1.1
1.0
—
—
—
0
0
204
505
2.03
17.19
9.1
7.2
—
—
—
0
0
185
442
2.10
17.08
1.6
1.3
—
—
—
0
0
19967
105649
0.92
16.87
2.8
2.6
—
—
—
0
0
290
819
1.78
16.59
2.8
2.9
29.1
28.4
umol/l
0.38
213
643
288
812
1.78
16.57
1.7
1.7
—
—
—
0
0
140
301
2.33
16.54
2.5
3.1
—
—
—
0
0
264
735
1.80
15.85
1.3
1.2
26.0
15.3
%
1.27
46
122
209
541
1.94
15.64
1.1
1.1
—
—
—
0
0
209
541
1.94
15.64
1.1
1.1
—
—
—
0
0
209
541
1.94
15.64
1.1
1.1
—
—
—
0
0
582
1984
1.47
15.63
1.3
1.2
—
—
—
0
0
289
831
1.74
15.61
1.1
1.0
10.5
9.8
u/ml
0.09
43
109
141
315
2.24
15.34
1.6
1.6
—
—
—
0
0
317
942
1.69
15.26
2.7
2.7
134.6
156.0
au/ml
0.28
48
120
129
278
2.33
15.21
3.3
2.8
—
—
—
0
0
91
164
2.78
15.19
1.2
1.2
—
—
—
0
0
65049
322445
1.13
15.05
28.2
16.1
257.3
253.0
e9/l
47.82
63864
313442
15170
71249
1.08
14.94
1.7
1.6
1.4
1.3
mmol/l
32.07
12864
60204
180
449
2.01
14.94
8.7
7.2
—
—
—
0
0
7109
32215
1.12
14.86
4.4
4.3
32.0
32.5
%
3.48
5094
22198
81
139
2.92
14.70
2.8
2.0
—
—
—
0
0
398
1268
1.57
14.62
1.2
1.1
14.5
10.7
u/ml
0.19
44
127
546
1864
1.47
14.60
1.4
1.4
12.7
11.6
umol/l
2.88
510
1766
281
819
1.72
14.53
1.2
1.2
0.3
0.6
g/l
0.65
22
46
362
1132
1.60
14.37
1.6
1.4
4.2
4.6
%
0.18
76
245
4260
18746
1.15
14.27
1.2
1.2
—
—
—
0
0
65084
322724
1.13
14.26
28.0
16.0
30.2
30.2
pg
16.44
64386
318178
234
652
1.80
14.08
1.3
1.2
38.2
40.8
g/l
1.57
130
332
675
2418
1.40
13.97
1.3
1.2
—
—
—
0
0
65104
322869
1.13
13.93
28.2
16.1
7.1
6.6
e9/l
279.81
63768
312955
65084
322768
1.13
13.90
28.1
16.0
90.7
90.6
fl
4.66
64391
318201
65090
322803
1.13
13.87
28.2
16.0
4.5
4.5
e12/l
173.60
63759
312903
380
1215
1.57
13.78
2.1
1.6
—
—
—
0
0
97
192
2.53
13.67
1.0
1.0
—
—
—
0
0
335
1045
1.61
13.47
3.2
3.2
7.9
8.2
mg/l
0.25
269
833
65100
322929
1.12
13.28
28.3
16.1
133.8
136.2
g/l
294.39
64395
318453
106
223
2.38
13.23
5.5
4.7
68.9
306.4
g/mol
0.55
96
201
300
915
1.64
13.19
2.0
1.9
9.0
9.6
mg/l
0.82
251
723
605
2150
1.41
13.14
1.1
1.1
249.8
261.9
mg/l
0.61
527
1897
134
315
2.13
13.02
1.1
1.1
—
—
—
0
0
564
1987
1.42
12.87
1.1
1.1
295.2
438.3
mg/l
0.47
512
1779
1078
4199
1.29
12.86
4.2
3.3
38.4
36.5
u/ml
0.13
1040
4041
68
115
2.96
12.71
1.2
1.2
—
—
—
0
0
1529
6219
1.24
12.69
4.8
3.7
—
—
—
0
0
761
2828
1.35
12.66
3.1
3.3
13.7
5.5
nmol/l
0.58
732
2750
411
1365
1.51
12.64
2.4
2.0
497.7
500.3
min
0.20
302
1039
96
197
2.44
12.64
1.1
1.1
—
—
—
0
0
621
2235
1.39
12.57
1.2
1.1
38.5
42.6
mg/l
1.23
513
1876
3437
15040
1.15
12.47
3.4
3.2
57.0
48.5
u/ml
0.40
3313
14540
1963
8206
1.20
12.42
1.1
1.1
9.2
4.9
u/ml
1.45
216
1149
287
880
1.64
12.40
2.6
2.0
—
—
—
0
0
152
384
1.98
12.30
1.3
1.3
39.5
211.2
titre
1.51
19
40
49
68
3.61
12.23
1.1
1.3
0.1
0.1
g/l
0.54
38
48
485
1679
1.45
12.18
3.0
3.3
127.1
123.3
nmol/l
0.09
474
1655
378
1250
1.52
11.90
1.5
1.4
—
—
—
0
0
529
1871
1.42
11.86
2.4
2.2
666.7
669.0
ml
0.04
373
1290
4311
19219
1.13
11.85
2.3
2.1
11.7
12.3
nmol/l
3.68
3787
17096
1071
4217
1.28
11.79
1.1
1.1
8471.7
858.8
iu/ml
0.44
263
959
33
34
4.86
11.60
5.5
4.6
4.0
6.7
mg/l
0.64
23
23
503
1774
1.42
11.48
1.1
1.1
3.3
4.2
u/ml
0.15
158
422
39
48
4.07
11.32
1.0
1.1
0.2
0.2
g/l
0.09
32
39
83
168
2.48
11.29
5.1
3.6
—
—
—
0
0
242
730
1.66
11.19
1.8
1.6
91.9
163.5
au/ml
1.39
25
94
194
550
1.77
11.16
1.6
1.5
0.4
0.4
ug/l
0.42
128
367
373
1248
1.50
11.15
1.2
1.3
—
—
—
0
0
2684
11638
1.16
11.06
1.1
1.1
—
—
—
0
0
605
2219
1.37
11.01
3.2
2.9
79.1
42.4
mg/l
1.33
446
1562
78
155
2.52
11.01
1.1
1.2
17.4
17.8
g/l
0.14
73
133
365
1220
1.50
10.97
1.6
1.6
2.8
9.8
nmol/l
0.87
290
1028
247
757
1.64
10.77
2.2
1.9
3897.5
3691.7
e6/l
0.02
174
507
437
1523
1.44
10.67
1.2
1.2
—
—
—
0
0
89
192
2.32
10.63
1.1
1.1
—
—
—
0
0
194
559
1.74
10.60
1.1
1.0
2.4
2.3
u/ml
—
10
23
44
63
3.50
10.58
1.0
1.0
—
—
—
0
0
483
1719
1.41
10.53
1.2
1.3
—
—
—
0
0
56
95
2.95
10.49
12.5
10.1
346.3
360.5
e6/l
0.02
42
66
56
95
2.95
10.49
7.9
5.9
—
—
—
0
0
473
1679
1.41
10.47
1.8
1.6
1807.4
1974.3
ml
1.13
119
376
539
1968
1.37
10.14
1.9
1.6
6.9
6.5
mmol/l
1.96
414
1421
450
1603
1.41
9.80
1.1
1.0
0.8
0.7
u/ml
0.05
72
218
503
1829
1.38
9.72
1.1
1.1
3.2
2.5
u/ml
0.16
181
502
42
62
3.39
9.72
1.0
1.0
—
—
—
0
0
42
62
3.39
9.72
1.0
1.0
—
—
—
0
0
42
62
3.39
9.72
1.0
1.0
—
—
—
0
0
42
62
3.39
9.72
1.0
1.0
—
—
—
0
0
7066
32676
1.09
9.68
8.4
5.9
—
—
—
0
0
258
822
1.57
9.68
1.1
1.1
3.2
7.9
u/ml
0.76
148
468
119
304
1.96
9.47
1.2
1.4
51.9
55.0
%
0.25
58
152
73
152
2.41
9.45
1.2
1.2
108.5
102.3
ug/l
0.11
48
95
136
365
1.87
9.39
1.1
1.1
4.2
7.9
pmol/l
0.37
17
48
218
672
1.63
9.37
2.1
1.8
6454.7
12911.0
e6/l
0.98
118
357
1157
4726
1.23
9.36
1.2
1.2
—
—
—
0
0
107
264
2.03
9.35
2.5
2.3
1.0
1.5
mmol/l
1.28
79
187
108
268
2.02
9.30
9.8
7.9
0.4
0.4
umol/l
0.00
99
239
118
304
1.94
9.18
1.6
1.2
283.3
124.7
titre
—
9
23
214
662
1.62
9.09
1.9
1.8
—
—
—
0
0
364
1266
1.44
9.08
1.1
1.1
1434.0
1523.0
miu/ml
0.75
364
1266
130
349
1.87
8.99
7.5
6.9
—
—
—
0
0
140
386
1.82
8.93
1.4
1.3
—
—
—
0
0
173
510
1.70
8.82
1.1
1.1
0.7
3.6
umol/24h
0.52
77
258
270
891
1.52
8.74
1.1
1.1
—
—
—
0
0
103
259
1.99
8.60
2.5
2.5
—
—
—
0
0
175
523
1.68
8.51
1.3
1.5
14.2
13.1
g/l
0.82
138
397
1998
8650
1.16
8.50
10.6
8.5
—
—
—
0
0
1235
5139
1.21
8.37
1.9
1.8
189.4
193.1
pmol/l
0.48
1174
4880
57
112
2.55
8.33
1.2
1.1
1.1
1.2
u/field
0.19
39
73
276
926
1.49
8.30
2.1
2.7
1.2
1.2
ug/l
0.12
251
888
121
327
1.85
8.25
1.4
1.5
305109.2
223623.6
nmol/l
0.15
98
271
322
1116
1.45
8.24
1.2
1.3
—
—
—
0
0
90
219
2.06
8.21
3.0
2.0
—
—
—
0
0
166
496
1.68
8.11
1.1
1.1
2.6
7.6
u/ml
1.23
127
350
382
1371
1.40
8.08
1.8
1.7
3.0
2.3
u/field
0.64
287
976
276
934
1.48
7.98
1.4
1.4
15.5
14.5
pmol/l
0.86
236
784
235
769
1.53
7.95
1.1
1.1
—
—
—
0
0
93
233
2.00
7.89
7.7
7.2
—
—
—
0
0
319
1117
1.43
7.76
2.1
2.1
165.8
83.9
ug/min
0.53
73
253
274
932
1.47
7.74
1.1
1.1
—
—
—
0
0
16
7
11.45
7.59
1.6
1.4
13.4
32.7
%
—
16
7
17381
83572
1.05
7.56
1.5
1.5
—
—
—
0
0
294
1021
1.44
7.49
1.1
1.1
569.1
483.5
ng/l
0.11
67
228
39
66
2.96
7.44
1.0
1.1
—
—
—
0
0
16
12
6.68
7.42
1.7
1.1
—
—
—
0
0
254
859
1.48
7.41
1.1
1.1
—
—
—
0
0
37
61
3.04
7.36
1.0
1.0
—
—
—
0
0
204
661
1.55
7.26
2.1
1.6
—
—
—
0
0
521
1999
1.31
7.21
2.1
2.0
2.0
2.4
u/field
0.79
254
857
157
478
1.65
7.21
1.3
1.2
63.6
43.0
mg/l
0.18
113
347
88
224
1.97
7.19
1.2
1.2
—
—
—
0
0
101
270
1.87
7.18
3.2
3.0
19.9
24.2
mg/l
2.43
95
257
94
246
1.91
7.11
1.1
1.1
—
—
—
0
0
33
52
3.18
7.04
5.8
5.4
1.0
1.2
mg/l
0.31
23
41
90
233
1.94
7.03
1.3
1.3
6.0
5.9
mmol/l
0.09
46
106
87
223
1.95
6.99
1.3
1.7
158.9
174.6
mmol/l
0.54
78
198
7160
33571
1.08
6.93
1.8
1.8
—
—
—
0
0
188
605
1.56
6.92
2.4
1.8
—
—
—
0
0
1760
7672
1.15
6.91
1.8
1.7
39.8
42.5
nmol/l
4.64
1714
7485
199
649
1.54
6.91
1.3
1.2
135.7
122.3
nmol/l
0.54
146
482
161
500
1.61
6.87
1.3
1.3
131.1
62.7
mu/l
0.74
112
378
290
1024
1.42
6.81
8.2
10.3
—
—
—
0
0
41
76
2.70
6.74
1.1
1.1
—
—
—
0
0
30
46
3.27
6.67
1.3
1.6
4.0
7.6
mg/l
0.58
25
46
104
288
1.81
6.67
1.0
1.0
0.1
0.2
u/ml
0.88
64
179
152
469
1.62
6.67
1.5
1.3
35.5
26.4
g/l
0.45
113
373
47
96
2.45
6.46
1.0
1.0
0.1
0.2
u/ml
0.13
22
32
978
4089
1.20
6.43
1.4
1.3
7.2
7.0
mmol/l
1.25
738
2861
80
206
1.95
6.39
2.2
1.9
1.3
1.3
umol/l
0.23
71
182
194
642
1.51
6.35
1.5
1.2
17.5
16.6
umol/l
1.50
170
578
23
30
3.84
6.34
1.0
1.0
—
—
—
0
0
146
453
1.61
6.30
1.1
1.1
—
—
—
0
0
22
28
3.93
6.25
1.4
1.4
0.7
0.6
u/field
0.16
13
13
72
180
2.00
6.24
1.3
1.1
17.9
15.9
nmol/l
0.34
20
45
67
163
2.06
6.23
1.3
1.6
37.7
35.1
%
0.19
47
111
145
451
1.61
6.20
1.2
1.2
7.1
9.0
u/ml
0.12
43
98
175
571
1.54
6.13
1.2
1.2
388.5
323.8
pmol/l
0.28
119
431
64
154
2.08
6.13
1.3
1.2
5.8
5.0
u/ml
0.07
58
125
1320
5690
1.16
6.08
4.3
2.9
28.6
24.9
mg/l
2.89
867
3420
98
275
1.79
6.07
1.0
1.1
0.5
4.3
u/ml
2.48
74
209
334
1236
1.35
6.01
1.6
1.6
5.9
5.6
mmol/24h
0.14
29
99
60
142
2.12
5.99
1.3
1.6
13.8
13.1
%
0.08
46
104
90
247
1.83
5.99
1.2
1.2
—
—
—
0
0
126
382
1.65
5.97
2.6
2.9
2707.4
1325.5
u/l
0.71
110
349
599
2401
1.25
5.96
1.6
1.5
—
—
—
0
0
786
4743
0.83
5.95
1.2
1.2
—
—
—
0
0
137
428
1.60
5.79
4.2
5.0
62.2
55.4
u/l
0.10
52
162
8292
43807
0.94
5.77
2.9
3.0
0.7
0.8
ug/l
4.07
5383
28756
30
51
2.95
5.75
1.2
1.1
—
—
mmol/l
—
0
0
3096
16979
0.91
5.73
1.7
1.6
—
—
—
0
0
92
260
1.77
5.60
1.8
1.7
1.6
1.7
mg/l
0.39
78
224
63
157
2.01
5.55
1.1
1.2
26.9
14.4
%
0.77
16
42
73
192
1.90
5.55
1.0
1.0
—
—
—
0
0
178
597
1.49
5.54
1.1
1.2
—
—
—
0
0
78
210
1.86
5.53
1.1
1.0
6.6
2.3
u/ml
—
10
14
210
729
1.44
5.51
2.0
1.6
—
—
—
0
0
122
376
1.63
5.47
1.7
1.6
—
—
—
0
0
50495
249809
1.04
5.27
24.2
13.9
332.0
332.9
g/l
75.66
50110
247925
21
30
3.51
5.20
1.0
1.1
—
—
—
0
0
41
88
2.33
5.16
1.0
1.0
0.1
0.1
u/ml
0.33
18
25
59
148
2.00
5.14
1.1
1.1
—
—
—
0
0
48
111
2.17
5.12
1.0
1.1
—
—
—
0
0
27
47
2.88
5.02
1.8
1.6
496.7
221.1
nmol/l
0.86
18
33
25
42
2.98
4.92
9.8
6.6
40.8
45.4
%
—
10
23
82
234
1.76
4.90
1.3
1.2
—
—
—
0
0
178
614
1.45
4.88
1.4
1.3
36.2
39.7
%
0.57
119
401
66
176
1.88
4.87
1.1
1.1
—
—
—
0
0
640
2649
1.21
4.81
2.1
1.8
1.6
3.2
mmol/l
—
5
11
200
709
1.41
4.75
1.7
1.4
—
—
—
0
0
639
2649
1.21
4.73
1.6
1.6
7.8
7.5
mmol/l
1.49
453
1437
57
146
1.96
4.73
2.5
2.2
—
—
—
0
0
1416
8010
0.88
4.71
1.4
1.5
—
—
—
0
0
65
175
1.86
4.68
1.1
1.1
13.7
16.8
iu/ml
0.15
28
43
1414
7991
0.88
4.64
1.4
1.5
—
—
—
0
0
135
445
1.52
4.64
2.3
2.4
7.8
7.3
mmol/l
0.58
87
263
128
418
1.53
4.59
2.0
2.1
2.7
2.7
mmol/l
0.03
118
376
49
120
2.05
4.59
1.2
1.4
1.3
1.2
%
0.08
35
80
39
88
2.22
4.45
13.2
8.4
—
—
—
0
0
21
34
3.09
4.40
1.0
1.2
—
—
—
0
0
11671
60686
0.96
4.39
4.0
4.3
21.7
22.0
%
1.77
5301
29341
128
423
1.52
4.37
1.1
1.1
—
—
—
0
0
54002
267853
1.04
4.31
3.9
3.7
1.3
1.3
mmol/l
88.09
49808
247808
797
4657
0.86
4.28
1.2
1.2
—
—
—
0
0
1457
8172
0.89
4.25
1.5
1.5
—
—
—
0
0
31
65
2.39
4.16
1.0
1.0
5.3
5.2
mmol/l
0.06
22
45
204
747
1.37
4.08
1.4
1.4
55.2
53.2
%
0.31
174
644
47
119
1.98
4.07
1.0
1.1
—
—
—
0
0
1136
5004
1.14
4.04
1.5
1.4
0.4
0.4
nmol/l
2.08
853
3993
18
28
3.22
4.01
1.0
1.0
—
—
—
0
0
18
28
3.22
4.01
2.0
2.0
—
—
—
0
0
18
28
3.22
4.01
2.0
2.0
—
—
—
0
0
18
28
3.22
4.01
2.0
2.0
—
—
—
0
0
49
128
1.92
3.91
1.7
2.5
20.9
18.9
mmol/l
0.23
41
109
20
34
2.95
3.91
1.1
1.1
—
—
—
0
0
45
114
1.98
3.91
1.2
1.1
26.2
14.2
u/ml
—
8
20
651
2758
1.18
3.89
1.4
1.4
11.3
11.8
mmol/l
0.67
165
577
128
436
1.47
3.84
1.2
1.2
—
—
—
0
0
94
300
1.57
3.80
1.0
1.0
—
—
—
0
0
86
269
1.60
3.77
1.1
1.0
0.6
0.4
u/ml
0.23
54
150
617
2610
1.19
3.77
4.4
4.8
106.2
112.9
u/ml
0.08
178
830
336
1336
1.26
3.77
1.6
1.9
—
—
—
0
0
525
2191
1.20
3.73
1.2
1.1
370.4
374.8
nmol/l
0.16
441
1881
53
145
1.83
3.71
1.2
1.1
36.4
37.3
s
0.42
45
123
55
153
1.80
3.67
1.5
1.3
15.2
17.0
pmol/l
0.34
44
130
121
414
1.46
3.58
1.6
1.8
44.9
62.5
pmol/l
0.59
104
343
64
189
1.70
3.51
1.0
1.1
0.7
0.7
u/ml
0.02
31
115
27
58
2.33
3.49
1.6
1.6
237.5
214.4
nmol/l
0.18
20
41
440
1821
1.21
3.45
1.0
1.0
—
—
—
0
0
50
138
1.81
3.44
1.0
1.0
—
—
—
0
0
92
300
1.54
3.43
1.1
1.0
0.8
2.1
u/ml
0.49
53
162
54
153
1.77
3.42
1.2
1.5
87.5
79.4
umol/l
0.57
49
139
28
62
2.26
3.40
1.1
1.0
—
—
—
0
0
17
29
2.94
3.33
1.1
1.2
—
—
—
0
0
977
4324
1.13
3.31
1.1
1.1
3.4
2.8
u/ml
0.54
423
2187
193
730
1.32
3.23
1.4
1.4
—
—
—
0
0
193
731
1.32
3.20
1.7
1.6
9.1
8.9
ug/l
0.26
193
731
21
43
2.45
3.02
1.3
1.3
115.6
42.0
e6/l
0.64
14
28
135
489
1.38
3.00
1.6
1.4
5.8
5.6
nmol/l
0.12
127
471
78
254
1.54
2.98
1.1
1.1
1.8
3.1
umol/24h
0.43
78
254
55
164
1.68
2.97
1.0
1.0
21.6
17.1
u/ml
0.21
45
134
38
102
1.87
2.89
1.1
1.2
—
—
—
0
0
42
117
1.80
2.86
1.2
1.3
16.9
16.8
umol/l
0.04
32
105
56
170
1.65
2.85
1.1
1.1
19.3
24.4
u/ml
—
7
32
56
170
1.65
2.85
1.1
1.1
24.6
29.2
u/ml
0.13
11
39
617
2680
1.15
2.82
2.7
2.8
—
—
—
0
0
70
228
1.54
2.70
1.4
1.1
21.2
20.7
mmol/l
0.37
54
181
194
756
1.29
2.69
1.3
1.2
—
—
—
0
0
96
335
1.44
2.67
2.0
1.8
—
—
—
0
0
87
298
1.46
2.66
1.1
1.0
0.5
0.6
u/ml
0.07
56
160
885
4952
0.89
2.64
1.3
1.3
3.4
3.7
ug/l
0.74
778
4470
51
155
1.65
2.61
1.1
1.1
1.1
1.1
u/ml
0.01
34
112
91
316
1.44
2.61
2.2
2.3
0.6
0.6
u/field
0.12
91
316
233
1445
0.81
2.58
1.3
1.3
—
—
—
0
0
22
50
2.20
2.58
1.0
1.0
9.3
13.0
u/ml
0.31
15
39
58
184
1.58
2.53
1.6
3.3
1.4
94.6
pmol/l
1.70
11
60
43
127
1.70
2.46
1.3
1.4
1631.6
946.7
u/l
0.17
38
112
168
652
1.29
2.44
1.0
1.1
—
—
—
0
0
14
26
2.70
2.43
2.9
2.7
—
—
—
0
0
1378
6333
1.09
2.42
1.3
1.3
—
—
—
0
0
390
1658
1.18
2.41
1.4
1.4
5.6
5.6
mmol/l
0.46
368
1572
22
52
2.12
2.38
1.6
1.3
—
—
—
0
0
25
63
1.99
2.32
1.0
1.0
0.3
1.0
u/ml
0.82
20
45
14
27
2.60
2.29
1.0
1.0
—
—
—
0
0
13
24
2.71
2.29
2.4
2.0
—
—
—
0
0
351
1487
1.18
2.28
1.3
1.2
—
—
—
0
0
321
1901
0.84
2.24
1.3
1.3
1.4
1.5
g/l
1.48
23
108
107
395
1.36
2.22
1.0
1.0
75.9
81.9
ug/l
0.79
86
327
48
152
1.58
2.15
1.8
1.7
0.6
0.8
%
0.25
37
119
14
28
2.50
2.15
1.1
1.1
—
—
—
0
0
139
537
1.30
2.14
2.6
2.5
—
—
—
0
0
389
1673
1.17
2.13
6.1
6.7
—
—
—
0
0
55
181
1.52
2.11
1.7
1.6
—
—
—
0
0
6
6
5.01
2.10
1.0
1.2
—
—
—
0
0
158
623
1.27
2.08
1.0
1.1
6.1
7.0
mg/g
0.79
144
596
20
49
2.04
2.02
1.2
1.1
0.0
0.1
g/l
—
7
12
58
196
1.48
1.98
1.1
1.0
0.3
0.2
u/ml
0.31
22
77
24
64
1.88
1.95
1.1
1.0
—
—
—
0
0
57
193
1.48
1.94
1.7
2.1
60.3
57.7
%
0.18
37
122
28
79
1.77
1.92
1.0
1.0
0.1
0.2
u/ml
—
8
13
16
37
2.17
1.86
1.3
1.3
167.8
213.7
nmol/l
0.42
11
26
5
5
5.01
1.81
20.0
10.2
5.6
4.3
ug/l
—
5
5
57
197
1.45
1.78
1.1
1.1
1.7
2.7
u/ml
—
10
14
23
63
1.83
1.75
1.0
1.0
—
—
—
0
0
12
25
2.40
1.73
1.1
1.0
—
—
—
0
0
24
67
1.79
1.73
3.6
2.3
—
—
—
0
0
196
812
1.21
1.72
1.4
1.4
—
—
—
0
0
18
46
1.96
1.67
1.1
1.0
0.0
0.1
g/l
—
8
14
19
50
1.90
1.63
1.2
1.1
102.9
49.2
mu/l
0.37
11
37
53
186
1.43
1.56
1.2
1.2
—
—
—
0
0
84
320
1.31
1.52
1.8
1.2
8.8
6.8
mmol/l
1.85
32
109
29
90
1.61
1.49
1.3
1.4
508.3
467.9
nmol/l
0.14
29
90
36
119
1.51
1.44
1.4
1.5
1.6
1.7
mpas
0.22
18
70
7
13
2.70
1.43
1.0
1.9
—
—
—
0
0
52
186
1.40
1.41
1.1
1.1
6.2
8.1
u/ml
0.46
38
126
45
157
1.44
1.40
1.3
1.5
342.5
313.0
umol/24h
0.47
45
157
8
15
2.67
1.37
1.0
1.1
13.1
17.3
umol/l
—
8
15
266
1522
0.87
1.32
1.6
1.4
—
—
—
0
0
80
310
1.29
1.32
1.1
1.2
—
—
—
0
0
23
71
1.62
1.24
1.3
1.2
—
—
—
0
0
54
200
1.35
1.23
1.0
1.0
0.4
1.1
u/ml
0.65
34
131
37
128
1.45
1.23
1.2
1.3
1.5
1.7
mg/l
0.63
30
107
349
1950
0.90
1.21
1.4
1.4
29.3
32.0
nmol/l
1.10
309
1806
80
315
1.27
1.20
1.3
1.2
—
—
—
0
0
5
9
2.78
1.16
1.0
1.1
—
—
—
0
0
18
53
1.70
1.15
1.4
1.4
156.8
136.1
nmol/l
0.18
13
34
19
57
1.67
1.14
2.0
3.1
—
—
—
0
0
14934
75848
0.98
1.14
4.6
4.9
3.1
3.3
ug/l
0.49
13339
68339
1854
9696
0.96
1.08
1.4
1.4
—
—
—
0
0
86
348
1.24
1.06
1.0
1.0
—
—
—
0
0
25
83
1.51
1.04
1.0
1.0
0.1
0.1
u/ml
0.09
19
43
24
79
1.52
1.03
1.6
1.7
—
—
—
0
0
19
59
1.61
1.03
1.3
1.3
—
—
—
0
0
30
104
1.44
1.02
1.1
1.1
0.0
0.1
mg/l
1.94
22
94
13
36
1.81
1.02
1.7
1.3
—
—
—
0
0
819
4368
0.94
1.01
1.6
1.6
—
—
—
0
0
15
44
1.71
0.99
1.5
1.2
—
—
—
0
0
22
72
1.53
0.98
1.0
1.0
—
—
—
0
0
2371
12305
0.96
0.98
1.5
1.4
—
—
—
0
0
19
60
1.59
0.97
1.4
1.7
131.9
113.5
ug/l
0.11
11
33
1428
6823
1.05
0.97
1.5
1.4
108.7
126.9
pmol/l
1.19
1391
6662
26
89
1.46
0.95
1.2
1.1
270.7
253.1
nmol/l
0.17
26
89
6
13
2.31
0.95
1.2
1.0
—
—
—
0
0
149
644
1.16
0.94
2.2
2.4
—
—
—
0
0
35
128
1.37
0.92
1.5
1.1
1.1
0.8
umol/24h
0.16
15
56
6
14
2.15
0.89
1.5
1.4
—
—
—
0
0
12
34
1.77
0.89
1.8
1.6
9.5
12.5
nmol/l
—
7
23
89
371
1.20
0.87
13.5
5.7
—
—
—
0
0
56113
280075
1.02
0.85
4.4
4.1
4.6
4.7
mmol/l
89.39
52273
261579
0
13
0.00
0.84
0.0
1.1
—
—
—
0
0
37
140
1.32
0.81
1.0
1.1
75.5
102.2
u/l
0.18
28
111
941
4477
1.05
0.80
1.7
1.7
—
—
—
0
0
46
180
1.28
0.80
1.1
1.1
—
—
—
0
0
342
1573
1.09
0.79
1.0
1.0
268.1
357.0
ng/l
2.97
243
1123
56970
284437
1.01
0.78
4.8
4.5
2.7
2.8
mmol/l
56.91
52676
264225
10
28
1.79
0.78
1.3
1.3
—
—
—
0
0
10
28
1.79
0.78
1.2
1.4
—
—
—
0
0
10
28
1.79
0.78
1.2
1.4
—
—
—
0
0
17
56
1.52
0.76
1.0
1.0
3.0
0.4
u/ml
—
10
29
291
1332
1.09
0.76
3.4
2.8
—
—
—
0
0
283
1295
1.09
0.74
1.1
1.1
—
—
—
0
0
343
1584
1.08
0.74
1.0
1.0
779.4
735.9
ng/l
0.93
230
1093
37
143
1.30
0.72
1.0
1.0
-1.9
-2.7
mmol/l
—
9
29
16
53
1.51
0.71
1.4
2.8
3.2
1.8
mu/l
0.45
16
53
140
792
0.88
0.71
3.3
3.1
—
—
—
0
0
140
791
0.89
0.70
6.6
6.2
—
—
—
0
0
55685
278053
1.01
0.68
4.3
4.1
1.4
1.5
mmol/l
138.83
51592
258642
16
54
1.48
0.66
1.3
1.1
—
—
—
0
0
26
97
1.34
0.65
1.2
1.1
—
—
—
0
0
18
63
1.43
0.64
1.1
1.0
0.1
0.1
u/ml
0.01
13
37
37
146
1.27
0.64
1.1
1.0
—
—
—
0
0
37
146
1.27
0.64
1.1
1.0
7.2
7.1
kpa
0.05
32
124
39
155
1.26
0.63
1.1
1.0
1.1
0.3
u/ml
0.66
20
73
215
983
1.10
0.62
2.7
3.0
—
—
—
0
0
23
85
1.35
0.61
1.0
1.1
231.6
221.0
pmol/l
0.04
13
45
6
16
1.88
0.61
1.0
1.0
—
—
—
0
0
35
138
1.27
0.61
1.0
1.0
1.1
0.4
u/ml
0.56
17
75
13
43
1.51
0.59
1.1
1.1
—
—
—
0
0
21
77
1.37
0.59
1.2
1.0
1.7
10.4
mmol/l
0.50
15
44
23
86
1.34
0.58
2.2
2.0
—
—
—
0
0
6
18
1.67
0.57
1.0
1.1
—
—
—
0
0
9
30
1.50
0.55
1.1
1.1
—
—
—
0
0
9
31
1.45
0.53
1.0
1.0
—
—
—
0
0
1466
7124
1.03
0.52
1.1
1.1
—
—
—
0
0
15
53
1.42
0.52
1.0
1.3
2.5
2.9
mmol/l
—
10
38
35
142
1.23
0.51
1.1
1.0
3.0
4.1
kpa
1.78
30
119
5
15
1.67
0.44
1.2
1.0
125.6
26.9
umol/l
—
5
9
126
692
0.91
0.44
2.5
2.6
142.7
95.4
ng/l
0.67
69
362
0
8
0.00
0.43
0.0
1.4
—
—
—
0
0
0
8
0.00
0.43
0.0
1.0
—
—
—
0
0
10
34
1.47
0.42
1.1
1.1
134.8
142.9
mmol/24h
—
10
34
37
155
1.20
0.42
1.5
1.7
0.8
0.7
umol/l
0.80
29
118
13
47
1.38
0.42
1.2
1.1
—
—
—
0
0
80
358
1.12
0.40
2.4
2.7
65.4
67.9
pmol/l
0.05
65
311
311
1475
1.06
0.40
3.3
2.8
—
—
—
0
0
10
35
1.43
0.38
1.0
1.1
—
—
—
0
0
38
162
1.17
0.37
1.3
1.4
—
—
—
0
0
42
183
1.15
0.33
1.1
1.3
—
—
—
0
0
28
118
1.19
0.32
1.0
1.0
—
—
—
0
0
431
2077
1.04
0.31
1.0
1.0
—
—
—
0
0
58
260
1.12
0.31
1.6
1.6
—
—
—
0
0
40
228
0.88
0.30
1.1
1.2
—
—
—
0
0
237
1129
1.05
0.29
1.4
1.4
71.8
73.1
%
0.66
224
1076
12
46
1.31
0.29
1.1
1.0
444.4
356.0
umol/l
—
5
21
11
42
1.31
0.27
1.0
1.0
0.3
0.2
u/ml
—
5
21
231
1105
1.05
0.26
1.4
1.4
486.6
602.1
mu/l
0.95
218
1052
19
79
1.20
0.26
1.1
1.2
—
—
—
0
0
10
38
1.32
0.25
1.0
1.1
1263.0
2382.1
titre
—
10
38
15
61
1.23
0.24
1.3
1.1
—
—
—
0
0
5
18
1.39
0.24
1.0
1.0
—
—
—
0
0
13
52
1.25
0.24
1.2
1.1
83.5
108.6
nmol/24h
0.86
13
52
156
741
1.05
0.24
1.6
1.3
—
—
—
0
0
0
6
0.00
0.22
0.0
1.0
—
—
—
0
0
36
161
1.12
0.22
1.2
1.4
—
—
—
0
0
0
7
0.00
0.22
0.0
1.0
—
—
—
0
0
113
537
1.05
0.19
1.9
1.8
2.3
3.8
ug/l
0.72
62
329
9
40
1.13
0.15
1.0
1.0
—
—
—
0
0
309
1512
1.02
0.13
2.0
2.0
4.0
3.7
ug/l
0.20
266
1334
221
1077
1.03
0.13
1.0
1.0
—
—
—
0
0
299
1467
1.02
0.11
2.0
2.1
2.5
2.4
ug/l
0.15
248
1234
5
32
0.78
0.08
1.0
1.0
—
—
—
0
0
12
67
0.90
0.07
4.3
5.6
0.2
0.2
mmol/l
0.01
12
67
8
48
0.83
0.07
1.0
1.0
165.0
164.9
g/l
—
8
48
84
432
0.97
0.06
6.0
5.7
—
—
—
0
0
85
416
1.02
0.05
2.3
2.3
3.8
3.8
ug/l
0.02
28
148
20
94
1.07
0.05
1.1
1.0
0.2
0.3
u/ml
0.19
12
39
41
198
1.04
0.04
5.3
2.3
7.8
11.8
%
0.65
12
51
597
3007
0.99
0.04
1.2
1.1
—
—
—
0
0
875
4401
1.00
0.04
3.2
2.3
13.2
13.1
%
0.63
863
4342
21
100
1.05
0.03
1.0
1.0
0.1
0.1
u/ml
0.12
13
46
18
86
1.05
0.02
1.0
1.0
0.3
0.2
u/ml
0.12
12
39
422
2108
1.00
0.01
1.4
1.3
66.0
88.3
pmol/l
0.72
159
603
12
57
1.05
0.00
1.9
1.4
1.4
2.3
mmol/24h
2.57
12
57
15
78
0.96
0.00
1.2
1.2
—
—
—
0
0
12
63
0.95
0.00
6.9
6.8
—
—
—
0
0
42
210
1.00
0.00
1.1
1.4
0.3
0.2
umol/l
0.24
13
74

Mortality – FinRegistry

Association

Association between endpoint PULM_INFECTIONS and mortality.

Females

Parameter HR [95% CI] p-value
PULM_INFECTIONS 2.696 [2.5, 2.91] < 0.001
Birth year 0.988 [0.98, 1.0] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 127782 out of 600825 females with PULM_INFECTIONS died.

Males

Parameter HR [95% CI] p-value
PULM_INFECTIONS 3.237 [2.98, 3.52] < 0.001
Birth year 0.978 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 139881 out of 608631 males with PULM_INFECTIONS died.

Mortality risk

Mortality risk for people of age

years, who have PULM_INFECTIONS.

N-year risk Females Males
1 0.192% 0.286%
5 0.961% 1.828%
10 2.17% 4.524%
15 4.088% 8.177%
20 7.123% 13.01%

Relationships between endpoints

Index endpoint: PULM_INFECTIONS – COPD/asthma/ILD related infections

GWS hits: 13

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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