This is a non-core endpoint: only basic statistics are computed.
See its core counterpart CD2_INSITU_VULVA_EXALLC for full statistics.
Carcinoma in situ of vulva
CD2_INSITU_VULVA
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditions
|
293065 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
266 |
4. Check minimum number of eventsNone |
266 |
5. Include endpointsNone |
266 |
6. Filter based on genotype QC (FinnGen only) |
266 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF9
- Parent code in ICD-10
- D07
- Name in latin
- Carcinoma in situ penis
Similar endpoints
↥List of similar endpoints to
Carcinoma in situ of vulva
based on the number of shared cases.
Similar with more cases:
- Carcinoma in situ of vulva
- Carcinoma in situ of other and unspecified genital organs
- Carcinoma in situ of other and unspecified genital organs
- In situ neoplasms
- In situ neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 266 | 266 | - |
| Unadjusted period prevalence (%) | 0.09 | 0.09 | - |
| Median age at first event (years) | 58.75 | 58.75 | - |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 239
- Matched controls
- 2389
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
180.3
185.4
182
41
ULA02
NOMESCO Finland
Kolposcopy
87.9
164.7
209
175
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
1142.1
161.2
140
*
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
+∞
155.8
132
*
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
117.9
90.5
94
13
D07.1
ICD-10 Finland
Carcinoma in situ: Vulva
+∞
84.5
76
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
18.2
84.4
162
247
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
1123.0
83.8
77
*
LFC00
NOMESCO Finland
Partial excision of vulva
436.7
67.1
64
*
D06BB10
ATC
imiquimod; topical
17.1
45.3
75
62
LEB00
NOMESCO Finland
Biopsy of vagina
26.0
41.3
58
29
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
49.6
40.2
48
12
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
11.1
38.4
79
102
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
13.8
29.4
52
47
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
6.4
26.7
79
170
8070/2-C51.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of vulva, NOS
+∞
26.5
25
*
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
4.2
24.1
146
652
N90.0
ICD-10 Finland
Mild vulvar dysplasia
60.5
23.6
27
5
LDA10
NOMESCO Finland
Curettage of cervix uteri
10.1
23.3
48
58
D07AD01
ATC
clobetasol; topical
4.8
22.3
88
258
A63.0
ICD-10 Finland
Anogenital (venereal) warts
11.7
20.3
38
38
8071/2-C51.9
ICD-O-3
Differentiated intraepithelial neoplasia of vulva, NOS
+∞
20.1
19
*
N90.4
ICD-10 Finland
Leukoplakia of vulva
54.2
17.3
20
*
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
8.0
16.8
39
57
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
5.3
15.4
50
114
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
+∞
14.7
14
*
N87.0
ICD-10 Finland
Mild cervical dysplasia
11.1
14.4
27
27
N76.6
ICD-10 Finland
Ulceration of vulva
32.3
14.1
18
6
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
56.9
14.0
16
*
N90.3
ICD-10 Finland
Dysplasia of vulva, unspecified
+∞
13.7
13
*
N90.8
ICD-10 Finland
Other specified noninflammatory disorders of vulva and perineum
26.5
11.3
15
6
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
114.9
10.5
11
*
N90.9
ICD-10 Finland
Noninflammatory disorder of vulva and perineum, unspecified
24.7
10.4
14
6
N87.1
ICD-10 Finland
Moderate cervical dysplasia
9.8
10.2
20
22
D06BB04
ATC
podophyllotoxin; topical
6.1
10.0
27
49
2333B
ICD-9 Finland
Carcinoma in situ of breast and genito-urinary system, Other and unspecified female genital organs[CARCINOMA IN SITU VULVAE]
104.0
9.5
10
*
J02AC01
ATC
fluconazole; systemic
2.3
9.3
144
938
8474
FHL
Coagulation, excision, or biopsy of local change (eg, condyloma, tumor) in operating room or anesthesia
19.5
9.0
13
7
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
3.1
8.9
53
202
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
93.2
8.5
9
*
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
7.5
8.4
19
27
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
7.5
8.4
19
27
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
10.6
8.2
15
15
N89.0
ICD-10 Finland
Mild vaginal dysplasia
34.6
8.1
10
*
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
7.4
7.9
18
26
B01AB10
ATC
tinzaparin; parenteral
3.9
7.9
32
91
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.1
7.6
43
158
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
7.6
106
638
C51.01
ICD-10 Finland
Squamous cell carcinoma of the labium majus
82.5
7.5
8
*
P01AB01
ATC
metronidazole; oral, rectal
2.1
7.3
128
842
WX320
NOMESCO Finland
Spinalanesthesy
2.3
7.2
75
392
LWA00
NOMESCO Finland
Repair of wound dehiscence in gynaecological surgery
41.3
6.8
8
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.1
6.7
96
577
C51.11
ICD-10 Finland
Squamous cell carcinoma of the labium minus
71.7
6.5
7
*
J01DB01
ATC
cefalexin; oral
2.4
6.0
204
1702
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: CD2_INSITU_VULVA – Carcinoma in situ of vulva
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).