Convergent concomitant strabismus

H7_CONVERSTRAB

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H50.0
  • Hospital discharge: ICD-9 3780
  • Hospital discharge: ICD-8 37300
  • Cause of death: ICD-10 H50.0
  • Cause of death: ICD-9 3780
  • Cause of death: ICD-8 37300

2 out of 7 registries used, show all original rules.

2477

4. Check minimum number of events

None

2477

5. Include endpoints

None

2477

6. Filter based on genotype QC (FinnGen only)

2477

Control definitions (FinnGen only)

Control exclude
H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H50
Name in latin
Strabismus convergens concomitans

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 31953 16397 15488
Only index persons 27242 14182 13060
Unadjusted period prevalence (%)
Whole population 0.45 0.47 0.43
Only index persons 0.51 0.52 0.50
Median age at first event (years)
Whole population 6.21 6.47 5.83
Only index persons 6.67 7.01 6.31

-FinnGen-

Key figures

All Female Male
Number of individuals 2477 1591 886
Unadjusted period prevalence (%) 0.49 0.54 0.39
Median age at first event (years) 9.92 10.03 9.74

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2230
Matched controls
22300
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H50.0
ICD-10 Finland
Convergent concomitant strabismus
+∞
323.0
1071
*
37300
ICD-8 Finland
Strabismus, Concomitans convergens
+∞
323.0
972
*
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
+∞
316.4
296
*
H50.30
ICD-10 Finland
Intermittent esotropy
1255.2
235.7
226
*
3780A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONCOMITANS CONVERGENS]
+∞
224.9
212
*
3503
FHL
Single muscle retroposition
+∞
209.8
198
*
3780B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONVERGENS ALTERNANS]
+∞
179.6
170
*
CEC00
NOMESCO Finland
Recession of extraocular muscle
1894.4
175.3
168
*
H53.0
ICD-10 Finland
Amblyopia ex anopsia
58.1
154.1
182
34
H50.1
ICD-10 Finland
Divergent concomitant strabismus
750.3
144.7
141
*
H50.2
ICD-10 Finland
Vertical strabismus
1390.4
135.9
131
*
H52.0
ICD-10 Finland
Hypermetropia
53.9
126.3
151
30
3507
FHL
Retroposition and resection
+∞
112.4
107
*
H50.31
ICD-10 Finland
Intermittent exotropia
1012.3
99.9
97
*
H53.2
ICD-10 Finland
Diplopia
16.3
95.6
158
104
H50.51
ICD-10 Finland
Esophoria
482.5
94.0
93
*
37301
ICD-8 Finland
Strabismus, Concomitans divergens
+∞
90.2
86
*
37720
ICD-8 Finland
Other diseases of retina and optic nerve, Amblyopia
311.1
88.4
89
*
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
+∞
68.1
65
*
CEC30
NOMESCO Finland
Resection of extraocular muscle
+∞
66.0
63
*
3504
FHL
Retroposition of two muscles
+∞
61.7
59
*
CEW99
NOMESCO Finland
Other operation on extraocular muscle
+∞
57.5
55
*
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
54.4
52
*
H50.9
ICD-10 Finland
Strabismus, unspecified
77.2
53.2
60
8
3505
FHL
Single muscle resection
+∞
52.3
50
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.4
49.6
260
827
H50.52
ICD-10 Finland
Exophoria
88.8
47.0
52
6
37302
ICD-8 Finland
Strabismus, Concomitans sursum sive deorsum vergens
+∞
42.8
41
*
H52.2
ICD-10 Finland
Astigmatism
23.2
42.4
61
27
H52.1
ICD-10 Finland
Myopia
8.0
42.3
98
127
37001
ICD-8 Finland
Refractive errors, Hypermetropia. Hyperopia
+∞
41.8
40
*
H50.8
ICD-10 Finland
Other specified strabismus
404.6
40.2
40
*
37303
ICD-8 Finland
Strabismus, Heterophoria (exophoria, esophroria, hypophoria)
+∞
38.6
37
*
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
62.6
37.2
43
7
3680A
ICD-9 Finland
Visual disturbances, Amblyopia ex anopsia
331.8
33.0
33
*
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
32.9
32.2
42
13
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.2
30.7
358
1798
CEC20
NOMESCO Finland
Recession and advancement of extraocular muscle
+∞
30.3
29
*
CEC50
NOMESCO Finland
Advancement of extraocular muscle
+∞
29.2
28
*
3510
FHL
Cardiac surgery on three or more muscles
+∞
29.2
28
*
37929
ICD-8 Finland
Blindness, one eye, specifically defined
295.7
28.8
29
*
3783A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Other and unspecified heterotropia
+∞
28.2
27
*
WX140
NOMESCO Finland
Parabulbar anesthesy
5.0
27.2
89
183
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
25.2
689
4653
3781A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS CONCOMITANS DIVERGENS]
+∞
25.0
24
*
3508
FHL
Transposition or anteposition
+∞
23.0
22
*
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
16.6
22.7
36
22
3781B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS DIVERGENS ALTERNANS]
+∞
20.9
20
*
H50.6
ICD-10 Finland
Mechanical strabismus
+∞
20.9
20
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
20.0
221
1072
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
18.8
523
3498
F83
ICD-10 Finland
Mixed specific developmental disorders
7.0
18.7
46
67
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
38.7
18.6
23
6
CE2W4
NOMESCO Finland
Eye movement mapping
67.1
17.7
20
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.6
17.4
508
3431
XCK00
NOMESCO Finland
Perimetry
2.8
17.4
115
427
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
16.1
17.0
27
17
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
+∞
16.7
16
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.5
16.6
132
545
H50.4
ICD-10 Finland
Other and unspecified heterotropia
90.8
16.6
18
*
3782B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Intermittent heterotropia[STRABISMUS DIVERGENS INTERMITTENS]
+∞
15.6
15
*
37309
ICD-8 Finland
Strabismus, Unspecified
+∞
15.6
15
*
3780X
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONVERGENS ALIUS]
+∞
15.6
15
*
ZXA05
NOMESCO Finland
Left side
1.7
15.6
399
2593
ZXA10
NOMESCO Finland
Bilateral
1.7
14.6
307
1882
3671A
ICD-9 Finland
Disorders of refraction and accommodation, Myopia
+∞
14.6
14
*
3670A
ICD-9 Finland
Disorders of refraction and accommodation, Hypermetropia
+∞
14.6
14
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.1
14.4
78
255
S01FA01
ATC
atropine; ophthalmic
15.5
14.4
23
15
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
8.3
14.3
31
38
F95
ICPC
Strabismus
75.6
13.6
15
*
37000
ICD-8 Finland
Refractive errors, Astigmatismus
+∞
13.6
13
*
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
140.8
13.5
14
*
R62.0
ICD-10 Finland
Delayed milestone
5.5
13.4
39
72
H54.5
ICD-10 Finland
Severe visual impairment, monocular
16.8
13.0
20
12
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
50.3
12.8
15
*
F82
ICD-10 Finland
Specific developmental disorder of motor function
6.8
12.7
31
46
3501
FHL
Myotomy or tenotomy
+∞
12.5
12
*
H50
ICD-10 Finland
Other strabismus
+∞
12.5
12
*
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
11.7
12.3
22
19
ZXA00
NOMESCO Finland
Right side
1.5
12.3
405
2795
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.2
12.2
125
585
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.0
12.2
160
833
3519
FHL
Other measure in this category
+∞
11.5
11
*
34301
ICD-8 Finland
Cerebral spastic infantile paralysis, Diplegia spastica
+∞
11.5
11
*
P85
ICPC
Mental retardation
12.8
11.1
19
15
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
11.0
124
610
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.2
10.9
106
487
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
10.7
161
884
3430A
ICD-9 Finland
Infantile cerebral palsy, Diplegic
60.3
10.6
12
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.1
10.6
121
599
H50.3
ICD-10 Finland
Intermittent heterotropia
+∞
10.4
10
*
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
+∞
10.4
10
*
37304
ICD-8 Finland
Strabismus, paralyticus. Paresis nervorum III, IV, VI
+∞
10.4
10
*
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
13.2
10.2
17
13
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.2
9.6
93
429
WX110
NOMESCO Finland
Local anesthesy
1.3
9.4
1454
13020
CAC44
NOMESCO Finland
Combined decompression of orbit
100.4
9.4
10
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
9.4
381
2735
WX002
NOMESCO Finland
Sedation and analgesia
1.5
9.4
297
2018
37003
ICD-8 Finland
Refractive errors, Anisometropia
+∞
9.4
9
*
CAC30
NOMESCO Finland
Decompression of orbit to sinuses
+∞
9.4
9
*
H51.8
ICD-10 Finland
Other specified disorders of binocular movement
+∞
9.4
9
*
3784B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Heterophoria[EXOPHORIA]
+∞
9.4
9
*
H26.4
ICD-10 Finland
After-cataract
2.3
9.4
86
387
H52.5
ICD-10 Finland
Disorders of accommodation
50.2
8.7
10
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
8.5
238
1572
Q12.0
ICD-10 Finland
Congenital cataract
27.6
8.5
11
*
CEC40
NOMESCO Finland
Resection and advancement of extraocular muscle
+∞
8.3
8
*
3782A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Intermittent heterotropia[STRABISMUS CONVERGENS INTERMITTENS]
+∞
8.3
8
*
37002
ICD-8 Finland
Refractive errors, Myopia
+∞
8.3
8
*
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
2.5
8.2
61
249
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
5.7
8.1
22
39
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
17.2
8.1
12
7
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.5
8.0
62
256
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
7.2
8.0
18
25
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.7
7.8
147
870
H51.1
ICD-10 Finland
Convergence insufficiency and excess
45.1
7.7
9
*
H50.50
ICD-10 Finland
Alternating hyperphoria
45.1
7.7
9
*
H03AA01
ATC
levothyroxine sodium; systemic
1.4
7.7
367
2714
CS494
NOMESCO Finland
Other visual field testing
3.3
7.7
37
115
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.9
7.6
101
533
TAB00
NOMESCO Finland
Lumbar puncture
2.0
7.5
87
435
WX402
NOMESCO Finland
General anaesthesia
1.5
7.3
302
2173
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.9
7.3
42
147
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
3.6
7.3
30
83
H52.4
ICD-10 Finland
Presbyopia
3.2
7.2
36
115
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.6
7.2
206
1368
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
30.1
7.1
9
*
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
20.1
7.1
10
5
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
7.1
322
2362
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
6.9
349
2604
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
2.7
6.9
45
170
H53.4
ICD-10 Finland
Visual field defects
3.2
6.8
34
109
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.8
6.8
41
150
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
6.8
224
1537
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.5
6.7
214
1456
N03AG01
ATC
valproic acid; systemic, rectal
1.8
6.5
113
656
N05AH03
ATC
olanzapine; systemic
1.7
6.5
121
718
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.1
6.5
71
351
R56.8
ICD-10 Finland
Other and unspecified convulsions
1.8
6.4
99
553
H50.39
ICD-10 Finland
Intermittent heterotropia
70.0
6.4
7
*
CEC80
NOMESCO Finland
Partial transposition of extraocular muscle
+∞
6.3
6
*
XCW11
NOMESCO Finland
Assessment of strabismus
+∞
6.3
6
*
3795A
ICD-9 Finland
Other disorders of eye, Nystagmus and other irregular eye movements
+∞
6.3
6
*
3699X
ICD-9 Finland
Blindness and low vision, Unspecified visual loss
+∞
6.3
6
*
3768
FHL
Eye examination under general anesthesia
26.7
6.2
8
*
WX400
NOMESCO Finland
Inhalation anesthesy
1.9
6.2
89
484
S01FA04
ATC
cyclopentolate; ophthalmic
3.9
6.2
23
59
H05.2
ICD-10 Finland
Exophthalmic conditions
12.5
6.1
10
8
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
10.0
6.0
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
60
176
3.47
17.30
1.6
1.6
—
—
—
0
0
115
530
2.23
14.01
1.2
1.8
449.8
485.5
mg/l
0.51
108
505
100
443
2.31
13.39
1.4
2.1
—
—
—
0
0
890
7121
1.39
13.05
5.2
4.9
36.8
36.6
g/l
0.34
830
6652
47
145
3.28
12.60
1.1
1.3
1.9
1.8
mmol/l
0.11
42
136
100
482
2.12
10.95
1.1
1.8
3.7
3.6
mmol/l
0.17
91
452
990
8247
1.33
10.58
8.1
6.6
1.2
1.2
mmol/l
0.09
869
7023
36
106
3.43
10.42
1.1
1.1
0.1
4.3
nmol/l
—
7
19
97
481
2.06
9.89
1.4
2.0
24.2
18.9
e6/l
0.21
75
369
97
481
2.06
9.89
1.5
2.0
2361.0
1318.7
e6/l
0.25
77
386
1206
10407
1.31
9.76
5.5
4.6
6.4
6.5
mmol/l
0.92
1114
9574
889
7440
1.30
8.72
7.7
6.1
1.2
1.2
mmol/l
0.66
823
6808
47
189
2.52
7.91
1.1
1.1
224.2
240.7
mg/l
0.26
42
162
1540
13929
1.28
7.84
7.6
6.9
78.0
77.1
u/l
0.34
1459
13167
48
197
2.46
7.75
1.2
1.2
34.3
37.1
mg/l
0.24
40
159
511
4030
1.34
7.48
4.6
4.1
—
—
—
0
0
52
228
2.31
7.28
1.6
2.2
—
—
—
0
0
1382
12401
1.26
7.22
4.5
3.8
1533.3
2129.8
e6/l
0.21
21
140
559
4538
1.30
6.56
4.7
4.1
91.6
93.9
%
1.47
546
4424
600
4924
1.29
6.47
3.2
2.5
—
—
—
0
0
579
4731
1.29
6.46
3.8
3.7
7.4
7.4
ph
0.22
83
906
1077
9486
1.24
6.30
3.6
3.2
0.0
0.0
estimate
0.80
171
1771
39
161
2.45
6.28
1.3
1.2
—
—
—
0
0
1077
9496
1.24
6.21
5.0
4.4
0.0
0.0
estimate
0.50
181
1830
1085
9575
1.24
6.20
3.7
3.2
0.0
0.0
estimate
1.06
176
1755
294
2192
1.39
6.11
7.2
6.5
1.1
1.1
mmol/l
0.12
277
2059
209
1467
1.46
6.07
9.9
9.6
—
—
—
0
0
1710
15869
1.25
6.03
4.6
3.9
14.6
14.5
pmol/l
1.15
1595
14774
771
6569
1.25
6.03
7.1
6.4
—
—
—
0
0
571
4695
1.28
6.01
2.2
2.1
151.9
247.8
u/l
2.27
538
4458
718
6074
1.26
5.96
8.3
6.8
1.2
1.1
inr
0.65
215
1934
528
4304
1.29
5.95
3.5
3.2
—
—
—
0
0
222
1583
1.44
5.94
11.4
8.5
13.5
13.0
kpa
0.55
208
1512
222
1583
1.44
5.94
11.4
8.5
5.1
5.1
kpa
0.06
207
1509
1018
8952
1.23
5.94
6.2
5.9
11.5
11.4
umol/l
0.06
955
8471
170
1155
1.51
5.81
4.4
4.1
73.2
76.7
ng/l
0.24
159
1043
366
2851
1.33
5.74
3.2
2.5
1.0
1.2
e6/l
0.39
225
1532
220
1580
1.43
5.67
11.5
8.6
1.2
1.0
mmol/l
0.16
163
1230
1450
13264
1.22
5.65
4.4
3.8
—
—
—
0
0
338
2622
1.33
5.44
5.2
4.2
0.8
0.8
mmol/l
1.32
319
2482
121
775
1.59
5.40
3.0
3.2
21.7
21.4
s
0.26
105
685
1001
8849
1.22
5.39
3.9
3.9
—
—
—
0
0
2075
19793
1.30
5.33
14.9
11.8
139.6
139.6
mmol/l
0.44
2022
19258
221
1609
1.41
5.29
4.6
5.2
1.8
1.8
mmol/l
0.05
183
1276
196
1400
1.43
5.22
12.2
9.2
95.9
96.1
%
0.16
186
1350
1354
12364
1.21
5.14
3.2
3.1
—
—
—
0
0
119
769
1.58
5.13
13.6
11.6
—
—
—
0
0
657
5582
1.24
5.13
3.1
3.1
2.4
2.4
mmol/l
0.19
596
5027
2078
19849
1.29
5.11
14.9
11.9
3.9
3.9
mmol/l
0.20
2020
19263
152
1041
1.49
5.03
3.0
2.9
197.7
154.5
ng/l
0.35
131
924
48
239
2.03
5.00
1.8
2.8
—
—
—
0
0
220
1617
1.40
4.99
4.6
5.2
6.0
5.8
kpa
1.17
215
1565
183
1307
1.43
4.89
12.8
9.3
121.5
123.1
g/l
0.48
174
1258
614
5228
1.23
4.63
3.5
3.0
52.5
79.3
e6/l
0.40
477
3930
208
1537
1.39
4.58
3.1
2.6
0.2
0.2
g/l
0.46
197
1450
564
4767
1.24
4.55
3.4
2.8
—
—
—
0
0
1146
10376
1.19
4.54
7.3
6.2
2.0
2.0
e9/l
0.91
1049
9253
250
1910
1.34
4.47
2.6
2.1
367.5
374.4
nmol/l
0.22
233
1772
1110
10035
1.19
4.44
7.4
6.2
0.0
0.0
e9/l
0.32
993
8744
601
5129
1.23
4.41
3.5
3.5
8.1
8.1
mmol/l
0.04
524
4450
304
2396
1.31
4.37
2.1
1.9
—
—
—
0
0
1079
9741
1.19
4.36
7.0
6.1
55.5
55.7
%
0.27
1021
9208
668
5769
1.22
4.35
2.4
2.3
—
—
—
0
0
194
1431
1.39
4.33
9.2
8.3
7.6
7.7
mmol/l
0.11
183
1378
1045
9421
1.19
4.26
7.1
6.3
2.8
2.8
%
0.02
992
8848
563
4789
1.23
4.25
3.5
2.9
0.5
0.4
e6/l
0.54
431
3535
1105
10011
1.19
4.25
7.4
6.2
0.6
0.6
e9/l
0.02
991
8731
494
4149
1.24
4.20
3.8
3.4
1.0
1.0
kg/l
0.06
72
609
88
558
1.60
4.17
9.0
5.6
1.9
1.6
%
0.99
82
519
2121
20420
1.27
4.15
13.7
11.1
21.8
21.0
mg/l
0.53
1665
15622
145
1024
1.44
4.15
4.8
5.9
24.0
24.0
mmol/l
0.04
132
945
50
271
1.86
4.14
1.6
1.5
—
—
—
0
0
215
1625
1.35
4.14
3.1
3.4
1.7
1.7
%
0.18
193
1473
314
2509
1.29
4.07
1.8
1.7
1148.8
1164.4
nmol/l
0.12
245
1944
726
6362
1.20
4.01
1.9
1.8
99.6
97.0
pmol/l
0.79
394
3442
401
3307
1.25
4.01
2.8
2.6
556.4
552.8
mosm/kgh2o
0.10
346
2837
418
3464
1.25
4.01
1.5
1.5
20.5
20.4
nmol/l
0.05
379
3047
87
556
1.59
4.01
9.0
5.6
0.9
0.9
%
0.12
81
520
80
501
1.62
4.00
3.1
3.1
—
—
—
0
0
1087
9869
1.18
4.00
7.1
6.3
29.9
29.9
%
0.03
1028
9302
77
479
1.63
3.96
1.5
1.4
285.1
310.8
ug/g
0.41
39
260
1136
10366
1.18
3.90
7.8
6.6
0.2
0.2
e9/l
0.19
1034
9220
1047
9490
1.18
3.90
7.4
6.5
8.4
8.3
%
0.47
996
8974
368
3016
1.26
3.88
3.6
3.3
352.4
486.2
ng/l
0.31
262
1940
1007
9108
1.18
3.83
7.3
6.4
0.7
0.7
%
0.02
952
8571
508
4322
1.22
3.80
4.1
4.1
13.3
9.4
mg/mmol
0.56
331
2797
84
542
1.57
3.74
3.4
1.9
7.7
4.3
iu/l
1.35
44
201
318
2575
1.27
3.71
2.3
2.3
13.9
14.2
umol/l
0.37
302
2382
63
380
1.68
3.67
3.3
3.2
36.7
33.1
umol/l
0.71
56
331
485
4121
1.22
3.66
3.3
3.4
790.4
366.9
mg/l
0.77
312
2666
424
3554
1.23
3.65
2.7
2.4
7.9
7.1
e6/l
0.42
376
3127
76
482
1.60
3.64
10.0
6.3
1.4
1.2
mmol/l
0.34
66
418
1933
18491
1.21
3.64
5.3
4.5
1.7
2.0
mu/l
1.35
1832
17389
201
1535
1.34
3.64
2.3
3.0
10.8
10.3
g/l
0.91
189
1413
633
5521
1.20
3.63
2.8
2.5
54.3
56.1
u/l
0.77
584
5148
724
6395
1.19
3.60
4.1
3.4
61.1
68.8
e6/l
0.20
515
4281
331
2704
1.26
3.59
3.4
2.7
4.3
3.2
e6/l
0.60
191
1393
17
62
2.75
3.58
1.1
1.4
—
—
—
0
0
178
1338
1.36
3.58
3.7
3.2
4.4
4.6
pmol/l
3.37
166
1194
510
4374
1.21
3.50
2.1
1.9
1.0
1.0
mg/l
0.31
400
3198
107
739
1.47
3.49
12.8
11.7
24.4
24.2
mmol/l
0.39
98
699
12
36
3.34
3.47
3.2
2.5
—
—
—
0
0
74
475
1.58
3.39
3.8
2.6
225.8
372.4
ug/l
0.69
69
438
659
5800
1.19
3.39
3.1
2.9
22.7
46.3
ng/l
1.74
353
3174
39
211
1.86
3.31
1.5
1.4
13.6
11.8
mmol/l
—
6
43
289
2348
1.26
3.29
2.3
2.3
2.5
2.4
g/l
0.42
268
2181
275
2227
1.26
3.22
1.8
1.6
—
—
—
0
0
343
2852
1.24
3.19
1.3
1.4
416.4
553.9
titre
1.12
66
549
54
327
1.67
3.15
12.9
7.7
12.0
11.5
mmol/l
0.38
48
294
19
79
2.42
3.13
1.7
1.7
—
—
—
0
0
54
328
1.66
3.12
12.9
7.7
104.9
105.4
mmol/l
0.24
48
295
408
3466
1.21
3.07
2.7
3.0
1447.1
981.2
ng/l
0.63
338
2862
10
29
3.46
3.04
1.5
1.4
—
—
—
0
0
178
1375
1.32
3.02
9.3
8.3
1.4
1.4
mmol/l
0.05
166
1315
2193
21335
1.24
3.00
14.7
12.0
72.0
71.6
umol/l
0.28
2193
21327
31
161
1.94
2.99
3.2
3.5
—
—
—
0
0
11
35
3.15
2.93
19.9
10.5
—
—
—
0
0
152
1155
1.34
2.90
2.7
3.2
70.2
72.3
e9/l
0.24
102
839
18
76
2.38
2.89
1.7
1.4
—
—
—
0
0
262
2140
1.25
2.87
2.5
2.4
22.7
23.9
%
0.87
225
1857
1908
18345
1.17
2.86
3.9
3.7
5.7
5.7
mmol/l
0.15
1783
17111
326
2730
1.22
2.84
2.8
2.7
2.4
2.4
mmol/l
0.20
276
2381
289
2397
1.23
2.76
1.2
1.2
—
—
—
0
0
41
240
1.72
2.74
1.5
1.6
—
—
—
0
0
1222
11403
1.14
2.74
10.4
9.1
4.0
3.9
e9/l
0.14
1096
9990
84
586
1.45
2.68
2.3
2.0
1.4
1.4
g/l
0.36
68
522
1759
16851
1.15
2.60
4.8
4.6
37.8
38.4
mmol/mol
1.83
1662
15943
1501
14228
1.14
2.58
4.3
3.8
10.0
9.8
mm/h
0.26
1420
13334
118
881
1.36
2.56
9.6
5.1
—
—
—
0
0
503
4426
1.17
2.54
2.3
2.2
2.6
2.8
mg/l
0.86
436
3841
297
2498
1.21
2.49
2.6
2.6
30.3
29.7
s
0.73
285
2422
10
35
2.86
2.30
2.1
1.3
—
—
—
0
0
113
856
1.34
2.26
13.4
7.2
24.5
24.5
mmol/l
0.01
104
794
0
60
0.00
2.24
0.0
1.5
—
—
—
0
0
2199
21506
1.20
2.19
10.4
8.8
26.3
26.8
u/l
0.65
2141
20886
72
511
1.42
2.15
3.8
2.1
3.5
2.1
ug/l
0.31
58
458
205
1690
1.23
2.12
2.4
2.5
29.6
67.0
u/l
0.73
173
1443
491
4371
1.15
2.12
2.3
2.2
—
—
—
0
0
152
1213
1.27
2.09
6.3
4.4
5.2
5.1
kpa
0.55
142
1141
34
208
1.64
2.01
1.2
1.5
325.0
399.4
pmol/l
0.51
28
161
150
1202
1.26
2.01
6.3
4.5
7.4
7.4
ph
0.08
13
118
20
104
1.93
2.00
3.2
3.3
772.8
989.3
u/ml
0.39
20
104
52
353
1.48
1.98
1.3
1.3
3.4
4.9
u/ml
0.59
27
157
548
4941
1.14
1.97
4.1
3.5
0.0
0.0
estimate
1.28
178
1780
168
1371
1.24
1.93
1.9
2.6
4.2
4.1
e9/l
0.39
139
1139
134
1065
1.27
1.93
2.5
2.7
67.1
67.0
g/l
0.07
126
992
399
3524
1.16
1.92
1.3
1.3
28.1
25.4
iu/ml
0.20
125
1061
1023
9593
1.11
1.88
3.0
2.8
96.6
92.3
ug/l
0.33
961
9054
119
940
1.28
1.81
6.9
4.6
—
—
—
0
0
47
320
1.48
1.79
5.2
5.5
430.0
373.4
umol/l
1.64
42
280
49
337
1.46
1.77
1.1
1.2
—
—
—
0
0
21
118
1.79
1.70
1.3
1.1
—
—
—
0
0
1495
14351
1.11
1.67
3.5
3.0
39.3
40.6
u/l
0.36
1429
13688
243
2090
1.18
1.66
3.3
3.1
8.0
7.2
umol/l
0.24
215
1787
110
872
1.27
1.65
7.6
4.8
24.4
24.5
mmol/l
0.06
102
836
526
4786
1.13
1.63
5.2
4.3
—
—
—
0
0
147
1209
1.23
1.61
1.4
1.4
—
—
—
0
0
227
1947
1.18
1.61
1.4
1.3
—
—
—
0
0
50
354
1.42
1.59
2.1
2.2
133.2
133.1
g/l
0.01
36
265
21
121
1.74
1.58
3.4
3.9
—
—
—
0
0
21
121
1.74
1.58
1.0
1.1
1549.4
1510.6
miu/ml
0.04
21
121
37
247
1.51
1.57
1.8
1.7
—
—
—
0
0
37
247
1.51
1.57
1.8
1.7
—
—
—
0
0
37
247
1.51
1.57
1.8
1.7
—
—
—
0
0
37
247
1.51
1.57
1.8
1.7
—
—
—
0
0
154
1280
1.22
1.54
1.2
1.2
55.0
130.9
titre
—
6
34
80
615
1.31
1.54
8.7
7.9
1.3
1.3
mg/l
0.12
75
586
15
79
1.90
1.49
3.1
2.7
100.8
111.3
ng/l
—
9
59
1921
18726
1.12
1.49
18.0
13.9
333.6
333.5
g/l
0.11
1915
18585
1891
18420
1.11
1.48
3.5
3.4
1.2
1.3
mmol/l
1.00
1786
17370
70
532
1.32
1.47
1.3
1.4
96.0
85.6
titre
—
5
55
51
369
1.39
1.45
2.0
2.1
39.4
38.2
g/l
0.71
45
326
16
88
1.82
1.41
2.3
1.4
—
—
—
0
0
63
826
0.76
1.40
1.5
1.5
—
—
—
0
0
65
847
0.76
1.38
1.5
1.5
—
—
—
0
0
120
986
1.23
1.37
1.1
1.1
—
—
—
0
0
128
1537
0.82
1.35
1.5
1.6
—
—
—
0
0
50
366
1.37
1.35
1.6
1.7
9272.1
12734.3
e6/l
0.41
43
274
2193
21575
1.14
1.35
12.2
10.1
—
—
—
0
0
80
628
1.28
1.35
3.6
4.2
0.3
0.3
g/l
0.01
36
309
27
175
1.55
1.34
1.1
1.3
—
196.3
—
0
8
45
615
0.73
1.33
1.0
1.1
3.5
1.1
u/ml
0.36
13
303
19
113
1.69
1.31
4.4
3.2
138.2
150.5
umol/l
0.12
14
66
5
18
2.78
1.28
1.0
3.9
—
—
—
0
0
48
353
1.37
1.27
4.5
5.2
—
—
—
0
0
142
1197
1.20
1.27
1.9
1.9
1.4
1.3
g/l
0.16
137
1114
22
138
1.60
1.26
1.2
1.2
1.1
1.0
ratio
—
7
57
64
823
0.77
1.26
1.5
1.4
—
—
—
0
0
16
92
1.74
1.25
2.2
1.3
—
—
—
0
0
2352
23281
1.20
1.24
20.0
16.3
259.7
259.7
e9/l
0.00
2310
22742
45
605
0.74
1.22
1.0
1.1
4.4
2.6
u/ml
—
9
160
22
140
1.58
1.20
1.2
1.2
—
—
—
0
0
252
2236
1.14
1.19
1.3
1.2
—
—
—
0
0
35
247
1.42
1.19
2.4
2.4
—
—
—
0
0
51
384
1.34
1.18
1.1
1.2
—
—
—
0
0
154
1319
1.18
1.17
1.3
1.3
49.8
45.9
au/ml
—
6
59
34
240
1.42
1.16
1.2
1.5
73.6
66.3
mmol/l
0.27
27
199
138
1173
1.19
1.15
2.8
2.5
—
—
—
0
0
2353
23304
1.19
1.15
20.0
16.2
89.9
89.9
fl
0.02
2334
23044
2354
23315
1.19
1.14
20.1
16.3
6.7
6.7
e9/l
0.06
2310
22727
2353
23305
1.19
1.14
19.9
16.2
30.0
30.1
pg
0.06
2333
23045
16
95
1.69
1.13
1.4
1.3
202.2
387.3
u/l
0.82
16
84
165
1426
1.17
1.13
2.3
2.3
19.8
20.8
au/ml
—
8
113
11
58
1.90
1.12
2.7
2.1
15.0
16.3
umol/l
0.23
11
58
8
40
2.00
1.12
1.0
1.2
—
—
—
0
0
34
242
1.41
1.11
1.1
1.2
—
43.5
—
0
15
363
3311
1.11
1.10
1.7
1.6
41009915.2
32680626.3
pmol/l
0.11
317
2858
1824
17823
1.09
1.10
17.1
13.5
13.5
13.4
%
0.38
1786
17468
2353
23310
1.19
1.10
20.0
16.3
4.6
4.6
e12/l
0.16
2307
22729
1963
19244
1.10
1.10
3.9
3.7
4.7
4.7
mmol/l
1.65
1867
18269
60
470
1.28
1.07
1.4
1.5
95.3
111.1
u/ml
0.61
13
88
30
419
0.71
1.06
1.0
1.1
0.1
0.4
u/ml
—
5
111
277
2495
1.12
1.06
1.9
1.9
—
—
—
0
0
48
366
1.32
1.05
3.8
3.1
26.0
21.7
mg/l
0.27
29
233
6
122
0.49
1.05
1.0
1.3
—
—
—
0
0
6
125
0.48
1.04
1.2
1.4
—
—
—
0
0
128
1093
1.18
1.03
2.9
3.3
—
—
—
0
0
5
22
2.28
1.03
1.0
1.2
—
—
—
0
0
585
5481
1.09
1.03
3.3
2.8
—
—
—
0
0
11
60
1.84
1.02
6.6
7.3
20.1
104.3
g/mol
1.30
11
54
2353
23321
1.18
1.02
20.1
16.4
136.7
136.7
g/l
0.02
2335
23057
937
8951
1.08
1.00
10.0
8.8
0.0
0.0
e9/l
0.52
767
7293
753
7935
0.93
1.00
2.5
2.4
—
—
—
0
0
62
495
1.26
0.98
1.3
1.5
—
—
—
0
0
0
32
0.00
0.95
0.0
1.8
—
—
—
0
0
13
77
1.69
0.95
1.2
1.3
—
—
—
0
0
1978
19436
1.09
0.94
4.2
4.0
2.9
2.9
mmol/l
0.22
1870
18313
9
51
1.77
0.94
1.1
1.0
4.0
7.7
mg/g
—
9
51
531
4974
1.09
0.94
7.6
7.0
—
—
—
0
0
48
373
1.29
0.94
1.6
1.8
0.6
0.8
g/l
1.87
39
286
83
689
1.21
0.93
2.8
3.2
—
—
—
0
0
44
339
1.30
0.92
2.7
3.5
34.9
67.1
mg/l
0.97
38
267
44
339
1.30
0.92
2.7
3.5
24.3
31.6
mg/l
1.75
38
267
9
52
1.73
0.92
1.1
1.0
—
—
—
0
0
51
643
0.79
0.92
1.0
1.1
5.9
6.5
u/ml
0.12
27
372
506
4741
1.08
0.89
1.8
1.6
1.3
1.4
mmol/l
1.47
442
4136
1948
19143
1.08
0.89
3.8
3.7
1.4
1.5
mmol/l
1.45
1846
18093
666
6310
1.08
0.88
1.5
1.6
—
—
—
0
0
82
685
1.20
0.87
3.7
3.9
0.6
0.7
%
0.32
77
664
113
1309
0.86
0.87
1.5
1.4
—
—
—
0
0
33
246
1.35
0.87
1.3
1.4
—
—
—
0
0
325
2990
1.10
0.87
2.8
2.6
104.7
111.7
ug/g
0.15
267
2389
6
30
2.00
0.87
2.8
2.1
—
—
—
0
0
362
3350
1.09
0.86
1.2
1.2
11.4
9.9
u/ml
0.14
129
1383
48
379
1.27
0.85
2.5
3.3
23.2
24.7
mmol/l
2.13
39
338
68
560
1.22
0.84
7.4
4.7
—
—
—
0
0
336
3102
1.10
0.84
1.6
1.6
—
—
—
0
0
173
1541
1.13
0.83
2.9
2.3
5921.6
6324.7
u/l
0.05
68
591
8
46
1.74
0.82
1.4
1.2
—
—
—
0
0
11
65
1.70
0.82
1.5
2.0
—
—
—
0
0
22
155
1.42
0.81
1.7
1.5
—
—
—
0
0
88
747
1.18
0.81
1.3
1.6
—
9.1
u/ml
—
0
25
115
999
1.16
0.80
1.1
1.1
—
—
—
0
0
66
546
1.21
0.79
1.1
1.2
—
—
—
0
0
34
259
1.32
0.79
2.9
3.6
—
—
—
0
0
10
58
1.73
0.79
3.0
3.1
—
—
—
0
0
470
4414
1.08
0.79
2.6
2.4
333.3
4087.2
umol/l
9.81
423
3935
6
33
1.82
0.79
1.5
1.5
—
—
—
0
0
48
384
1.25
0.78
2.3
1.5
—
—
—
0
0
39
304
1.29
0.78
2.4
2.5
—
—
—
0
0
41
323
1.27
0.76
3.6
3.8
—
—
—
0
0
26
348
0.74
0.76
1.3
1.6
—
—
—
0
0
169
1514
1.12
0.76
2.4
2.2
12.7
12.6
nmol/l
0.08
156
1345
36
279
1.29
0.75
3.2
3.3
14.5
66.6
u/ml
0.53
36
244
12
75
1.60
0.75
5.0
2.6
—
—
—
0
0
30
227
1.33
0.74
2.2
2.9
1.3
1.2
e9/l
0.28
23
132
57
469
1.22
0.74
1.5
1.3
—
6.6
—
0
8
575
5457
1.07
0.73
1.4
1.3
1.5
1.9
u/ml
0.45
159
1442
24
176
1.37
0.72
2.0
3.1
—
—
—
0
0
57
686
0.83
0.71
1.1
1.1
0.8
2.1
u/ml
2.00
20
312
7
40
1.75
0.71
1.3
1.1
—
—
—
0
0
5
26
1.92
0.70
2.6
2.7
—
—
—
0
0
5
26
1.92
0.70
1.2
1.3
—
—
—
0
0
15
101
1.49
0.70
2.1
1.4
—
—
—
0
0
92
797
1.16
0.69
1.1
1.2
0.3
1.1
u/ml
—
6
69
12
77
1.56
0.68
2.7
4.7
—
—
—
0
0
781
7503
1.06
0.68
2.0
1.9
—
—
—
0
0
25
187
1.34
0.68
2.5
2.5
12.1
11.2
%
0.24
19
114
54
447
1.21
0.67
4.0
2.5
7.4
6.1
umol/l
0.22
37
344
97
846
1.15
0.67
2.6
2.2
—
—
—
0
0
7
43
1.63
0.66
1.7
1.6
—
—
—
0
0
29
223
1.30
0.66
1.3
1.3
—
—
—
0
0
217
1990
1.10
0.66
1.3
1.5
—
—
—
0
0
34
428
0.79
0.66
4.4
3.5
7.4
7.4
ph
0.14
29
356
10
155
0.64
0.65
1.0
1.2
—
—
—
0
0
323
3454
0.93
0.65
1.4
1.5
—
—
—
0
0
234
2156
1.09
0.64
1.3
1.3
—
—
—
0
0
19
137
1.39
0.64
2.1
1.6
16.2
24.8
umol/l
1.03
19
130
17
120
1.42
0.64
1.2
1.1
—
—
—
0
0
238
2198
1.09
0.63
1.6
1.5
—
—
—
0
0
35
279
1.26
0.62
1.2
1.2
—
—
—
0
0
36
445
0.81
0.61
1.3
1.3
—
—
—
0
0
215
1981
1.09
0.60
1.2
1.2
—
—
—
0
0
0
20
0.00
0.60
0.0
1.2
—
57.9
—
0
5
40
488
0.82
0.60
1.1
1.1
2.3
5.5
u/ml
1.87
16
199
9
141
0.64
0.60
1.2
1.3
—
67.4
—
0
14
23
174
1.32
0.60
2.6
3.3
—
—
—
0
0
32
254
1.26
0.59
1.0
1.1
—
—
—
0
0
8
52
1.54
0.59
2.5
2.4
—
—
—
0
0
157
1725
0.90
0.59
1.2
1.3
—
—
—
0
0
163
1485
1.10
0.58
4.0
3.8
—
—
—
0
0
86
755
1.14
0.57
3.7
2.8
—
—
—
0
0
31
247
1.26
0.56
1.4
1.3
—
0.5
nmol/l
—
0
12
6
36
1.67
0.56
1.2
1.2
—
—
—
0
0
6
36
1.67
0.56
1.2
1.2
—
—
—
0
0
6
36
1.67
0.56
1.2
1.2
—
—
—
0
0
16
115
1.39
0.56
1.9
2.3
—
—
—
0
0
17
124
1.37
0.55
2.5
2.7
42.2
43.9
%
—
9
37
45
376
1.20
0.54
1.1
1.1
—
—
—
0
0
12
82
1.47
0.54
1.4
1.3
—
—
—
0
0
102
910
1.13
0.54
1.9
1.5
9.0
8.7
u/l
0.08
83
711
167
1533
1.10
0.53
1.6
1.4
26.4
24.0
iu/l
0.43
133
1268
136
1237
1.11
0.52
1.3
1.2
—
—
—
0
0
9
133
0.68
0.51
1.4
2.9
—
—
—
0
0
6
100
0.60
0.51
2.7
3.0
—
—
—
0
0
6
100
0.60
0.51
5.3
5.9
—
—
—
0
0
120
1085
1.11
0.51
2.2
2.2
7.2
7.4
ug/l
0.05
105
975
19
144
1.32
0.50
1.2
1.3
—
—
—
0
0
497
4759
1.06
0.50
1.6
1.5
2.2
2.2
g/l
0.19
312
2938
32
389
0.82
0.49
1.2
1.1
—
—
—
0
0
12
167
0.72
0.49
3.4
3.2
—
—
—
0
0
174
1609
1.09
0.48
18.3
17.7
1.1
1.2
inr
2.67
22
254
23
181
1.27
0.48
1.2
1.1
—
—
—
0
0
56
486
1.16
0.46
2.8
3.6
250.2
874.6
u/ml
0.82
45
412
43
365
1.18
0.46
1.1
1.1
—
—
—
0
0
37
310
1.20
0.45
3.8
2.7
—
—
—
0
0
184
1711
1.08
0.45
1.2
1.2
146.7
146.6
iu/ml
0.00
78
640
19
147
1.29
0.45
1.4
1.4
3259.2
88348.1
e6/l
1.09
13
99
7
50
1.40
0.45
1.4
1.4
—
—
—
0
0
140
1288
1.09
0.44
3.4
4.2
5.1
18.5
ug/l
1.66
113
1001
31
256
1.21
0.44
2.6
2.7
—
—
—
0
0
15
197
0.76
0.44
2.9
4.0
—
—
—
0
0
36
426
0.84
0.43
1.2
2.4
1.0
0.8
nmol/l
1.25
31
369
2023
20041
1.05
0.43
15.3
11.9
40.4
40.4
%
0.02
1591
16298
30
361
0.83
0.43
4.7
3.7
2.1
2.3
mmol/l
0.24
16
220
47
405
1.16
0.43
8.4
4.1
3.8
3.8
mmol/l
0.12
47
376
5
31
1.61
0.43
1.0
6.9
—
—
—
0
0
279
2944
0.94
0.42
1.3
1.3
—
—
—
0
0
197
2103
0.93
0.42
2.4
2.5
0.5
0.7
ug/l
3.29
101
1139
137
1264
1.09
0.42
3.5
3.2
—
—
—
0
0
0
17
0.00
0.40
0.0
2.1
—
3.7
—
0
7
88
796
1.11
0.40
1.3
1.3
—
—
—
0
0
12
88
1.37
0.40
5.0
2.5
—
—
—
0
0
25
303
0.82
0.39
1.7
1.4
—
—
—
0
0
31
367
0.84
0.39
1.3
1.1
113.3
1248.7
iu/ml
—
7
112
21
169
1.24
0.38
1.1
1.3
0.2
0.7
u/ml
0.77
11
60
9
67
1.34
0.38
2.0
2.1
—
208.2
—
0
10
151
1407
1.08
0.38
1.4
1.4
—
—
—
0
0
5
37
1.35
0.37
1.0
1.2
—
—
—
0
0
443
4271
1.05
0.36
3.5
3.1
—
—
—
0
0
147
1374
1.07
0.35
5.3
4.6
0.0
0.6
%
0.93
28
326
39
446
0.87
0.33
1.1
1.1
8.2
5.6
u/ml
0.26
18
195
17
136
1.25
0.33
1.3
1.2
—
71.4
—
0
11
6
86
0.70
0.33
1.0
1.1
—
—
—
0
0
6
47
1.28
0.32
1.3
1.2
—
—
—
0
0
6
47
1.28
0.32
1.3
1.2
—
—
—
0
0
6
47
1.28
0.32
1.3
1.2
—
—
—
0
0
165
1556
1.06
0.31
1.5
1.3
225.9
219.6
u/ml
0.04
155
1450
42
475
0.88
0.31
1.6
1.5
0.3
0.4
nmol/l
0.90
35
380
14
175
0.80
0.30
4.3
2.9
3.3
35.1
nmol/l
0.50
14
169
32
277
1.16
0.30
3.1
2.7
1.5
1.6
mmol/l
0.17
32
269
7
54
1.30
0.30
1.1
1.8
—
—
—
0
0
10
75
1.33
0.30
1.0
1.0
800.4
760.7
ng/l
—
5
49
15
185
0.81
0.29
1.3
1.4
—
—
—
0
0
54
487
1.11
0.29
7.4
4.0
1.3
1.4
mmol/l
0.35
54
479
9
120
0.75
0.27
1.1
1.2
—
—
—
0
0
110
1032
1.07
0.26
1.3
1.3
181.5
230.0
miu/ml
1.01
54
518
14
171
0.82
0.26
1.1
1.0
—
—
—
0
0
50
454
1.10
0.25
1.1
1.1
—
—
—
0
0
17
142
1.20
0.24
1.1
1.0
—
—
—
0
0
15
124
1.21
0.24
1.3
1.5
36.8
32.3
%
—
10
79
45
408
1.10
0.23
1.9
1.9
—
—
—
0
0
40
361
1.11
0.23
1.6
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
9.0
—
67.8
—
0
5
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
0.2
—
0
5
0
12
0.00
0.21
0.0
1.0
—
3106.0
—
0
7
23
201
1.15
0.21
1.1
1.2
0.4
3.2
u/ml
1.27
11
83
27
239
1.13
0.21
1.5
1.4
2.5
2.8
g/l
0.45
22
170
27
239
1.13
0.21
1.5
1.4
0.4
0.4
g/l
0.33
22
169
67
624
1.08
0.21
1.7
1.8
0.2
0.2
g/l
0.26
61
584
69
644
1.07
0.20
1.1
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
37
407
0.91
0.20
1.2
1.2
—
—
—
0
0
27
240
1.13
0.20
1.5
1.4
—
—
—
0
0
27
240
1.13
0.20
1.5
1.4
6.8
6.7
g/l
0.08
21
172
6
52
1.15
0.19
1.0
1.3
17.8
17.6
umol/l
—
6
46
10
81
1.24
0.18
1.8
1.8
—
—
—
0
0
20
175
1.14
0.18
1.2
1.6
45.4
57.0
%
—
10
117
22
194
1.14
0.18
1.5
1.3
40.1
32.5
nmol/l
0.48
22
168
14
164
0.85
0.18
2.4
2.8
0.9
0.9
nmol/l
0.02
14
121
18
206
0.87
0.18
1.1
1.2
1.4
11.6
u/ml
—
6
73
166
1599
1.04
0.18
2.3
2.3
—
—
—
0
0
67
629
1.07
0.18
1.3
1.2
—
—
—
0
0
161
1671
0.96
0.17
4.2
3.5
—
—
—
0
0
28
310
0.90
0.17
2.8
2.3
17.2
16.8
%
0.17
16
154
167
1610
1.04
0.17
2.1
2.2
—
—
—
0
0
20
176
1.14
0.17
1.2
1.2
—
—
—
0
0
5
67
0.75
0.17
2.0
1.2
—
—
—
0
0
13
152
0.85
0.17
1.0
1.2
—
—
—
0
0
17
148
1.15
0.17
1.1
1.1
—
—
—
0
0
24
215
1.12
0.16
1.3
1.3
—
—
—
0
0
368
3602
1.03
0.16
3.5
3.7
1.9
2.0
ug/l
0.03
338
3287
33
360
0.92
0.16
2.1
2.6
20.9
114.6
ug/min
3.50
16
232
167
1614
1.04
0.16
2.5
2.3
—
—
—
0
0
37
341
1.09
0.15
4.5
3.5
—
—
—
0
0
131
1263
1.04
0.14
2.4
2.4
—
—
—
0
0
11
93
1.18
0.14
1.5
1.6
—
—
—
0
0
157
1520
1.04
0.14
5.1
4.4
0.8
0.9
%
0.06
34
413
68
645
1.06
0.14
1.7
1.8
1.2
1.2
g/l
0.06
62
604
10
118
0.85
0.14
1.0
1.4
—
—
—
0
0
74
706
1.05
0.13
1.2
1.2
—
—
—
0
0
26
283
0.92
0.12
4.7
3.8
83.0
29.2
u/ml
0.65
26
276
81
776
1.05
0.12
2.4
2.2
—
—
—
0
0
13
148
0.88
0.12
2.2
2.4
—
—
—
0
0
10
85
1.18
0.12
1.0
1.0
—
—
—
0
0
52
494
1.05
0.11
1.1
1.1
—
—
—
0
0
125
1213
1.03
0.11
2.1
1.6
347.0
293.3
mu/l
1.03
111
1093
10
86
1.16
0.11
1.1
1.1
—
—
—
0
0
357
3625
0.98
0.10
1.7
1.7
—
—
—
0
0
38
403
0.94
0.10
1.2
1.0
5.5
3.4
u/ml
0.29
16
212
39
368
1.06
0.10
4.2
4.0
58.1
56.1
%
0.56
39
368
5
45
1.11
0.09
5.0
7.5
—
—
—
0
0
5
45
1.11
0.09
2.0
2.1
—
—
—
0
0
38
359
1.06
0.09
3.8
3.7
3.7
4.0
e9/l
0.48
38
359
15
166
0.90
0.09
1.1
1.2
—
—
—
0
0
24
223
1.08
0.09
1.3
1.3
—
—
nmol/l
—
0
0
6
54
1.11
0.09
2.7
1.8
—
—
—
0
0
30
282
1.06
0.09
1.5
1.4
—
—
—
0
0
84
814
1.03
0.08
1.8
1.7
—
—
—
0
0
15
136
1.10
0.08
1.1
1.0
—
—
—
0
0
162
1587
1.02
0.08
2.2
2.3
—
—
—
0
0
5
61
0.82
0.08
2.8
2.1
2.4
2.1
ug/l
—
5
53
5
61
0.82
0.08
2.2
2.1
3.6
3.3
ug/l
—
5
54
22
236
0.93
0.08
2.8
3.3
1.4
1.4
%
0.02
15
199
585
5901
0.99
0.08
2.0
2.0
—
—
—
0
0
7
66
1.06
0.08
1.1
1.7
—
—
—
0
0
6
75
0.80
0.07
4.2
2.2
—
—
—
0
0
6
75
0.80
0.07
1.0
2.6
—
—
—
0
0
8
74
1.08
0.07
1.0
1.0
—
—
—
0
0
124
1266
0.98
0.07
3.8
3.5
1.2
1.2
mmol/l
0.17
112
1094
15
163
0.92
0.07
1.6
1.6
—
—
—
0
0
9
87
1.03
0.07
2.7
3.2
—
—
—
0
0
9
101
0.89
0.06
1.1
1.1
—
—
—
0
0
9
103
0.87
0.06
1.1
1.2
—
—
—
0
0
9
105
0.86
0.06
4.2
3.9
1.3
1.5
ug/l
—
9
98
142
1395
1.02
0.06
5.1
4.2
0.7
0.5
%
0.36
26
311
130
1276
1.02
0.06
1.2
1.2
—
—
—
0
0
14
152
0.92
0.06
1.4
1.1
—
—
—
0
0
48
497
0.97
0.06
1.7
1.3
—
—
—
0
0
29
276
1.05
0.06
1.4
1.6
—
—
—
0
0
19
178
1.07
0.05
1.3
1.2
—
—
—
0
0
19
178
1.07
0.05
1.2
1.4
56.8
220.1
pmol/l
—
8
58
14
129
1.09
0.05
1.1
1.0
—
—
—
0
0
51
494
1.03
0.05
1.1
1.1
—
—
—
0
0
147
1447
1.02
0.05
5.3
4.5
0.2
0.1
%
0.17
33
380
16
149
1.07
0.05
1.3
1.1
—
—
—
0
0
18
169
1.07
0.05
1.2
1.1
—
—
—
0
0
79
805
0.98
0.04
1.6
1.7
—
—
—
0
0
471
4686
1.01
0.03
1.7
1.7
—
—
—
0
0
16
151
1.06
0.03
3.3
7.3
12.3
11.5
%
0.49
16
151
105
1036
1.01
0.03
1.3
1.3
—
—
—
0
0
60
590
1.02
0.02
8.5
8.7
—
—
—
0
0
19
182
1.04
0.02
1.7
2.9
598.0
725.7
e6/l
—
5
62
19
198
0.96
0.02
6.4
4.1
477.2
97.7
u/ml
—
9
56
10
107
0.93
0.02
11.6
6.6
—
—
—
0
0
10
107
0.93
0.02
2.5
2.0
—
2.1
—
0
12
150
1490
1.01
0.01
2.4
2.4
—
—
—
0
0
17
175
0.97
0.00
13.8
11.9
0.7
0.6
mmol/l
0.79
17
159
56
565
0.99
0.00
1.2
1.3
207.5
237.7
u/ml
0.63
38
335
10
98
1.02
0.00
1.1
1.1
124.2
240.8
iu/ml
—
10
98
41
407
1.01
0.00
2.2
2.4
—
—
—
0
0
12
117
1.03
0.00
2.0
2.3
790.5
607.7
ml
—
6
83
16
163
0.98
0.00
1.2
1.1
—
—
—
0
0
24
237
1.01
0.00
2.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
64
0.94
0.00
1.0
1.2
—
—
—
0
0
8
87
0.92
0.00
1.1
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
2.6
—
0
5
0
7
0.00
0.00
0.0
1.1
—
111.4
—
0
7
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
15
150
1.00
0.00
1.6
2.2
—
—
—
0
0
6
65
0.92
0.00
1.0
2.9
—
—
—
0
0
6
68
0.88
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
67.5
—
0
8
0
8
0.00
0.00
0.0
8.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
10
100
1.00
0.00
1.0
1.5
133.6
137.5
nmol/l
—
10
100
0
8
0.00
0.00
0.0
1.3
—
198.6
—
0
8
0
7
0.00
0.00
0.0
1.3
—
32.7
—
0
7
0
8
0.00
0.00
0.0
1.9
—
4.5
—
0
8
5
54
0.93
0.00
1.2
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_CONVERSTRAB and mortality.

Females

Parameter HR [95% CI] p-value
H7_CONVERSTRAB 1.266 [1.03, 1.56] 0.027
Birth year 0.993 [0.98, 1.0] 0.115

During the follow-up period (1.1.1998 — 31.12.2019), 231 out of 8389 females with H7_CONVERSTRAB died.

Males

Parameter HR [95% CI] p-value
H7_CONVERSTRAB 1.261 [1.02, 1.56] 0.03
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 237 out of 7962 males with H7_CONVERSTRAB died.

Mortality risk

Mortality risk for people of age

years, who have H7_CONVERSTRAB.

N-year risk Females Males
1 0.12% 0.25%
5 0.741% 1.622%
10 1.733% 3.733%
15 3.213% 7.03%
20 5.683% 11.43%

Relationships between endpoints

Index endpoint: H7_CONVERSTRAB – Convergent concomitant strabismus

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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