Convergent concomitant strabismus

H7_CONVERSTRAB

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H50.0
  • Hospital discharge: ICD-9 3780
  • Hospital discharge: ICD-8 37300
  • Cause of death: ICD-10 H50.0
  • Cause of death: ICD-9 3780
  • Cause of death: ICD-8 37300

2 out of 7 registries used, show all original rules.

2507

4. Check minimum number of events

None

2507

5. Include endpoints

None

2507

6. Filter based on genotype QC (FinnGen only)

2408

Control definitions (FinnGen only)

Control exclude
H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H50
Name in latin
Strabismus convergens concomitans

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 31953 16397 15488
Only index persons 27242 14182 13060
Unadjusted period prevalence (%)
Whole population 0.45 0.47 0.43
Only index persons 0.51 0.52 0.50
Median age at first event (years)
Whole population 6.21 6.47 5.83
Only index persons 6.67 7.01 6.31

-FinnGen-

Key figures

All Female Male
Number of individuals 2408 1545 863
Unadjusted period prevalence (%) 0.49 0.55 0.40
Median age at first event (years) 10.24 10.51 9.76

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2507
Matched controls
25070
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
37300
ICD-8 Finland
Strabismus, Concomitans convergens
+∞
307.7
1068
*
H50.0
ICD-10 Finland
Convergent concomitant strabismus
16384.0
307.7
1234
*
H53.0
ICD-10 Finland
Amblyopia ex anopsia
44.4
307.7
212
52
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
3860.0
307.7
346
*
H50.30
ICD-10 Finland
Intermittent esotropy
1584.9
293.5
280
*
H52.0
ICD-10 Finland
Hypermetropia
25.1
268.5
191
82
3780A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONCOMITANS CONVERGENS]
+∞
248.1
234
*
3503
FHL
Single muscle retroposition
+∞
229.8
217
*
CEC00
NOMESCO Finland
Recession of extraocular muscle
2016.6
206.0
197
*
3780B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONVERGENS ALTERNANS]
+∞
198.6
188
*
H53.2
ICD-10 Finland
Diplopia
11.2
181.7
198
191
H50.1
ICD-10 Finland
Divergent concomitant strabismus
898.4
173.1
168
*
H50.2
ICD-10 Finland
Vertical strabismus
333.2
154.6
155
5
3507
FHL
Retroposition and resection
1203.7
118.8
115
*
H50.31
ICD-10 Finland
Intermittent exotropia
594.9
116.0
114
*
H50.51
ICD-10 Finland
Esophoria
173.6
111.3
116
7
37720
ICD-8 Finland
Other diseases of retina and optic nerve, Amblyopia
518.3
101.3
100
*
37301
ICD-8 Finland
Strabismus, Concomitans divergens
+∞
97.5
93
*
H50.52
ICD-10 Finland
Exophoria
27.2
89.1
61
23
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
24.0
85.2
61
26
H52.1
ICD-10 Finland
Myopia
6.9
81.9
129
195
CEC30
NOMESCO Finland
Resection of extraocular muscle
+∞
80.7
77
*
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
771.3
76.7
75
*
3504
FHL
Retroposition of two muscles
+∞
74.3
71
*
H52.2
ICD-10 Finland
Astigmatism
10.7
73.0
80
77
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.3
71.1
292
957
H50.9
ICD-10 Finland
Strabismus, unspecified
98.0
69.3
76
8
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
69.1
66
*
CEW99
NOMESCO Finland
Other operation on extraocular muscle
+∞
63.8
61
*
3505
FHL
Single muscle resection
+∞
58.6
56
*
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
14.9
52.9
47
32
H50.8
ICD-10 Finland
Other specified strabismus
183.9
52.1
54
*
37001
ICD-8 Finland
Refractive errors, Hypermetropia. Hyperopia
+∞
49.1
47
*
37302
ICD-8 Finland
Strabismus, Concomitans sursum sive deorsum vergens
+∞
47.0
45
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.2
47.0
459
2299
37303
ICD-8 Finland
Strabismus, Heterophoria (exophoria, esophroria, hypophoria)
+∞
43.9
42
*
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
11.9
39.5
40
34
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
11.0
37.4
40
37
F83
ICD-10 Finland
Mixed specific developmental disorders
7.6
36.5
52
70
3680A
ICD-9 Finland
Visual disturbances, Amblyopia ex anopsia
352.1
35.0
35
*
CEC20
NOMESCO Finland
Recession and advancement of extraocular muscle
+∞
34.4
33
*
3783A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Other and unspecified heterotropia
+∞
34.4
33
*
WX140
NOMESCO Finland
Parabulbar anesthesy
3.8
34.1
107
292
CEC50
NOMESCO Finland
Advancement of extraocular muscle
+∞
33.4
32
*
XCK00
NOMESCO Finland
Perimetry
3.1
29.8
129
433
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
29.7
842
5837
3510
FHL
Cardiac surgery on three or more muscles
+∞
29.2
28
*
37929
ICD-8 Finland
Blindness, one eye, specifically defined
66.8
28.9
33
5
3508
FHL
Transposition or anteposition
+∞
28.2
27
*
3781A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS CONCOMITANS DIVERGENS]
+∞
28.2
27
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.0
23.2
263
1373
3781B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS DIVERGENS ALTERNANS]
+∞
22.9
22
*
H50.6
ICD-10 Finland
Mechanical strabismus
+∞
22.9
22
*
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
19.1
22.6
34
18
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.3
22.6
171
761
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.6
22.2
599
4047
ZXA05
NOMESCO Finland
Left side
1.7
20.1
448
2875
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
19.9
575
3934
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.9
19.6
91
318
H50.4
ICD-10 Finland
Other and unspecified heterotropia
201.5
19.6
20
*
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
+∞
18.8
18
*
H51.8
ICD-10 Finland
Other specified disorders of binocular movement
+∞
18.8
18
*
F95
ICPC
Strabismus
38.7
18.6
23
6
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.0
18.5
202
1038
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
25.2
18.2
25
10
3782B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Intermittent heterotropia[STRABISMUS DIVERGENS INTERMITTENS]
+∞
17.7
17
*
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
+∞
17.7
17
*
3780X
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONVERGENS ALIUS]
+∞
17.7
17
*
37309
ICD-8 Finland
Strabismus, Unspecified
+∞
17.7
17
*
R62.0
ICD-10 Finland
Delayed milestone
4.6
17.3
41
91
ZXA10
NOMESCO Finland
Bilateral
1.7
16.6
353
2230
H50
ICD-10 Finland
Other strabismus
171.1
16.5
17
*
ZXA00
NOMESCO Finland
Right side
1.6
16.4
467
3169
P85
ICPC
Mental retardation
14.4
16.3
27
19
F82
ICD-10 Finland
Specific developmental disorder of motor function
5.3
16.1
32
61
CE2W4
NOMESCO Finland
Eye movement mapping
24.6
16.0
22
9
37000
ICD-8 Finland
Refractive errors, Astigmatismus
+∞
15.6
15
*
3519
FHL
Other measure in this category
+∞
15.6
15
*
3670A
ICD-9 Finland
Disorders of refraction and accommodation, Hypermetropia
+∞
14.6
14
*
3671A
ICD-9 Finland
Disorders of refraction and accommodation, Myopia
+∞
14.6
14
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.2
14.3
120
558
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.0
14.1
166
876
H26.4
ICD-10 Finland
After-cataract
2.2
14.0
118
549
S01FA01
ATC
atropine; ophthalmic
12.7
13.9
24
19
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
13.6
13.7
23
17
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
5.1
13.6
28
55
H54.5
ICD-10 Finland
Severe visual impairment, monocular
12.1
13.6
24
20
3501
FHL
Myotomy or tenotomy
+∞
13.6
13
*
H50.3
ICD-10 Finland
Intermittent heterotropia
+∞
13.6
13
*
37304
ICD-8 Finland
Strabismus, paralyticus. Paresis nervorum III, IV, VI
+∞
13.6
13
*
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.3
13.4
99
437
Z3231
NOMESCO Finland
Registered nurse
1.5
13.3
568
4183
Z3229
NOMESCO Finland
Other healthcare associate professional
1.9
13.2
165
889
WX402
NOMESCO Finland
General anaesthesia
1.5
13.0
474
3380
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.2
12.3
48
152
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
12.3
143
752
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.8
12.0
175
991
WX002
NOMESCO Finland
Sedation and analgesia
1.6
12.0
343
2319
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
11.7
408
2877
H53.4
ICD-10 Finland
Visual field defects
3.3
11.5
43
133
3784B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Heterophoria[EXOPHORIA]
+∞
11.5
11
*
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
35.2
11.3
14
*
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
17.1
11.2
17
10
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
11.2
685
5354
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.8
11.0
155
869
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
11.0
423
3041
ZXD20
NOMESCO Finland
Day surgery
1.6
10.9
267
1740
Q12.0
ICD-10 Finland
Congenital cataract
28.1
10.7
14
5
34301
ICD-8 Finland
Cerebral spastic infantile paralysis, Diplegia spastica
60.3
10.6
12
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.5
10.6
312
2120
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
3.9
10.6
30
77
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
10.6
1730
15605
CAC30
NOMESCO Finland
Decompression of orbit to sinuses
110.5
10.4
11
*
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
110.5
10.4
11
*
37003
ICD-8 Finland
Refractive errors, Anisometropia
+∞
10.4
10
*
3782A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Intermittent heterotropia[STRABISMUS CONVERGENS INTERMITTENS]
+∞
10.4
10
*
H51.1
ICD-10 Finland
Convergence insufficiency and excess
+∞
10.4
10
*
3768
FHL
Eye examination under general anesthesia
32.7
10.3
13
*
CS494
NOMESCO Finland
Other visual field testing
3.0
10.3
44
148
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
3.4
10.1
35
103
H52.4
ICD-10 Finland
Presbyopia
2.5
10.0
60
241
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.0
10.0
107
548
R56.8
ICD-10 Finland
Other and unspecified convulsions
1.9
10.0
115
604
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.7
9.9
189
1156
AA1AD
NOMESCO Finland
CT of head and brain
1.4
9.5
404
2952
WX400
NOMESCO Finland
Inhalation anesthesy
2.0
9.4
103
531
3430A
ICD-9 Finland
Infantile cerebral palsy, Diplegic
30.1
9.4
12
*
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
17.6
9.4
14
8
37002
ICD-8 Finland
Refractive errors, Myopia
+∞
9.4
9
*
CEC40
NOMESCO Finland
Resection and advancement of extraocular muscle
+∞
9.4
9
*
N03AG01
ATC
valproic acid; systemic, rectal
1.8
9.3
134
756
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
9.2
284
1949
CAC44
NOMESCO Finland
Combined decompression of orbit
36.8
9.0
11
*
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
2.3
9.0
67
298
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
7.5
8.9
20
27
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
3.3
8.8
32
98
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
8.7
262
1787
N05BA09
ATC
clobazam; oral
3.9
8.7
25
65
H52.5
ICD-10 Finland
Disorders of accommodation
50.2
8.7
10
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.2
8.6
70
324
ZXE00
NOMESCO Finland
One hour or less
1.3
8.5
807
6682
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
4.2
8.5
22
53
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
90.4
8.4
9
*
XCW11
NOMESCO Finland
Assessment of strabismus
90.4
8.4
9
*
H50.39
ICD-10 Finland
Intermittent heterotropia
90.4
8.4
9
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
8.4
723
5907
TAB00
NOMESCO Finland
Lumbar puncture
1.9
8.4
101
540
H54.7
ICD-10 Finland
Unspecified visual loss
4.7
8.3
19
41
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.8
8.2
117
660
S01CA03
ATC
hydrocortisone and antiinfectives; ophthalmic
3.7
8.2
25
68
WX704
NOMESCO Finland
Intubation
1.7
8.1
155
950
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
2.5
8.1
48
193
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.6
7.9
186
1201
WX702
NOMESCO Finland
Supraglottic ventilation device
1.8
7.9
112
631
H53.1
ICD-10 Finland
Subjective visual disturbances
1.7
7.8
126
738
WX725
NOMESCO Finland
Noninvasive ventilation
1.8
7.7
103
571
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
7.6
764
6350
H26.02
ICD-10 Finland
Presenil cataract
2.4
7.6
48
199
R52.9
ICD-10 Finland
Pain, unspecified
1.6
7.6
190
1246
183
Kela drug reimbursment
Lamotrigin and topiramate
3.3
7.5
27
82
F79
ICD-10 Finland
Unspecified mental retardation
80.3
7.4
8
*
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
13.4
7.4
12
9
CD2S4
NOMESCO Finland
Photography of eye
6.0
7.4
19
32
H47.2
ICD-10 Finland
Optic atrophy
8.4
7.3
15
18
3795A
ICD-9 Finland
Other disorders of eye, Nystagmus and other irregular eye movements
+∞
7.3
7
*
H03AA01
ATC
levothyroxine sodium; systemic
1.4
7.2
425
3276
R42
ICD-10 Finland
Dizziness and giddiness
1.4
7.1
368
2777
XA800
NOMESCO Finland
Neuropsychological investigation
1.9
7.1
91
497
TPH07
NOMESCO Finland
Cathetrisation of artery
1.6
7.1
165
1064
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
10.0
7.0
13
13
H81
ICPC
Excessive ear wax
1.5
7.0
248
1749
S01FA04
ATC
cyclopentolate; ophthalmic
3.3
7.0
25
76
N03AX14
ATC
levetiracetam; systemic
2.2
6.9
54
246
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.5
6.9
251
1779
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.5
6.8
246
1741
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
6.1
6.8
17
28
N03AX12
ATC
[U] gabapentin; oral
1.4
6.7
281
2043
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
16.7
6.7
10
6
N28
ICPC
Limited function/disability (N)
2.9
6.7
30
104
H16.0
ICD-10 Finland
Corneal ulcer
1.8
6.7
104
602
WX882
NOMESCO Finland
High dependency care
2.1
6.7
62
302
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
2.4
6.7
44
186
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.6
6.7
149
951
XCK10
NOMESCO Finland
Photography of fundus of eye
1.6
6.6
135
842
WX720
NOMESCO Finland
Own respiration
1.8
6.4
87
484
M41.4
ICD-10 Finland
Neuromuscular scoliosis
11.0
6.3
11
10
SPAT1365
SPAT
Health check-up performed during first study year due to special need in students of upper secondary schools or vocational schools
3.9
6.3
18
47
CEC80
NOMESCO Finland
Partial transposition of extraocular muscle
+∞
6.3
6
*
3785A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Paralytic strabismus
+∞
6.3
6
*
3699X
ICD-9 Finland
Blindness and low vision, Unspecified visual loss
+∞
6.3
6
*
3431A
ICD-9 Finland
Infantile cerebral palsy, Hemiplegic
+∞
6.3
6
*
N03AX16
ATC
[U] pregabalin
1.3
6.2
396
3083
N02BE01
ATC
paracetamol; systemic, rectal
1.3
6.2
1959
18433
N06AX21
ATC
duloxetine; oral
1.4
6.2
234
1673
104
Kela drug reimbursment
Thyroid insufficiency
1.7
6.2
110
664
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
2.5
6.1
37
151
ZXE20
NOMESCO Finland
More than three and less than five hours
1.5
6.0
211
1485

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
60
178
3.43
17.00
1.6
1.6
—
—
—
0
0
115
532
2.22
13.89
1.2
1.8
449.81
487.00
mg/l
0.54
108
507
100
447
2.29
13.12
1.4
2.0
—
—
—
0
0
899
7208
1.39
12.95
5.2
4.9
36.77
36.61
g/l
0.38
841
6747
39
105
3.76
12.82
1.1
1.1
0.12
4.34
nmol/l
—
7
19
47
145
3.28
12.60
1.1
1.2
1.88
1.83
mmol/l
0.10
42
136
1007
8363
1.34
11.10
8.0
6.6
1.21
1.22
mmol/l
0.16
886
7177
100
483
2.11
10.89
1.1
1.8
3.67
3.63
mmol/l
0.15
91
453
1221
10518
1.31
10.08
5.5
4.6
6.37
6.48
mmol/l
1.12
1133
9681
97
483
2.05
9.78
1.4
2.0
24.23
18.90
e6/l
0.21
75
370
97
483
2.05
9.78
1.5
2.0
2360.99
1323.14
e6/l
0.24
77
387
904
7550
1.31
9.06
7.6
6.1
1.21
1.22
mmol/l
0.79
841
6967
47
186
2.56
8.16
1.1
1.1
224.19
242.98
mg/l
0.31
42
159
48
194
2.50
7.99
1.2
1.2
34.28
37.34
mg/l
0.26
40
157
1560
14107
1.28
7.97
7.6
6.9
77.98
77.13
u/l
0.31
1478
13360
795
6655
1.28
7.49
3.6
3.2
30.91
30.46
u/l
0.11
761
6350
515
4075
1.33
7.34
4.5
4.1
—
—
—
0
0
52
230
2.29
7.14
1.6
2.2
—
—
—
0
0
1737
16054
1.27
6.74
4.6
3.9
14.59
14.49
pmol/l
1.07
1619
14941
1392
12547
1.25
6.72
4.5
3.8
1533.29
2132.86
e6/l
0.21
21
140
39
158
2.49
6.52
1.6
1.6
—
—
—
0
0
582
4756
1.29
6.47
2.2
2.1
153.52
247.14
u/l
2.23
549
4516
565
4605
1.29
6.40
4.6
4.1
91.65
93.91
%
1.46
550
4489
298
2221
1.39
6.20
7.2
6.5
1.09
1.09
mmol/l
0.14
281
2086
584
4806
1.28
6.10
3.8
3.7
7.40
7.40
ph
0.22
83
913
611
5057
1.28
6.10
3.1
2.5
—
—
—
0
0
1093
9680
1.23
5.92
3.7
3.2
0.00
0.00
estimate
1.06
178
1766
1085
9602
1.23
5.92
5.0
4.4
0.00
0.00
estimate
0.50
183
1840
1086
9612
1.23
5.92
3.6
3.2
0.00
0.00
estimate
1.08
188
1890
211
1491
1.45
5.92
9.8
9.4
—
—
—
0
0
172
1167
1.51
5.91
4.4
4.1
73.39
76.57
ng/l
0.22
160
1056
223
1596
1.44
5.85
11.3
8.5
13.56
13.05
kpa
0.56
209
1525
223
1596
1.44
5.85
11.3
8.6
5.15
5.14
kpa
0.06
208
1522
907
7887
1.24
5.82
2.6
2.3
75.48
73.67
nmol/l
1.09
837
7300
1028
9068
1.23
5.73
6.2
5.9
11.49
11.40
umol/l
0.05
964
8599
2103
20029
1.31
5.72
14.8
11.8
139.64
139.60
mmol/l
0.43
2048
19490
343
2648
1.34
5.70
5.1
4.1
0.81
0.82
mmol/l
1.59
324
2519
816
7032
1.24
5.66
11.2
10.2
1.18
1.16
inr
0.46
239
2217
532
4364
1.28
5.66
3.5
3.2
—
—
—
0
0
221
1591
1.43
5.62
11.4
8.6
1.18
1.04
mmol/l
0.20
165
1258
1073
9521
1.22
5.61
7.7
6.6
—
—
—
0
0
122
777
1.60
5.57
3.0
3.1
21.70
21.42
s
0.28
106
686
369
2891
1.32
5.54
3.2
2.5
1.00
1.18
e6/l
0.40
225
1551
905
7900
1.23
5.53
3.3
3.0
5.85
5.90
ph
0.28
92
816
1465
13422
1.22
5.52
4.4
3.8
—
—
—
0
0
2106
20087
1.30
5.47
14.9
11.9
3.94
3.94
mmol/l
0.20
2046
19494
1374
12529
1.21
5.36
3.2
3.1
—
—
—
0
0
223
1628
1.41
5.25
4.6
5.1
1.78
1.77
mmol/l
0.02
195
1331
197
1408
1.43
5.22
12.2
9.2
95.93
96.15
%
0.17
187
1358
666
5658
1.24
5.20
3.1
3.1
2.35
2.35
mmol/l
0.51
608
5127
222
1636
1.39
4.95
4.6
5.1
5.96
5.85
kpa
0.94
217
1584
119
777
1.56
4.92
13.6
11.5
—
—
—
0
0
184
1315
1.43
4.89
12.8
9.4
121.14
123.22
g/l
0.65
177
1278
1006
8954
1.21
4.89
2.5
2.5
—
—
—
0
0
48
243
1.99
4.80
1.8
2.8
—
—
—
0
0
1162
10506
1.20
4.71
7.4
6.2
1.95
2.02
e9/l
0.98
1070
9408
152
1061
1.46
4.60
3.0
3.0
197.73
153.80
ng/l
0.35
131
943
609
5194
1.23
4.50
3.4
3.5
8.07
8.08
mmol/l
0.02
532
4552
1122
10144
1.19
4.47
7.4
6.2
0.04
0.04
e9/l
0.34
1004
8849
620
5302
1.23
4.46
3.5
3.0
52.20
78.61
e6/l
0.40
480
3980
1121
10137
1.19
4.45
7.4
6.2
0.55
0.56
e9/l
0.04
1004
8856
378
3059
1.28
4.43
3.6
3.3
351.39
481.41
ng/l
0.31
269
1975
1092
9856
1.19
4.42
7.0
6.1
55.46
55.69
%
0.27
1036
9338
251
1922
1.34
4.42
2.6
2.1
366.18
373.55
nmol/l
0.24
234
1783
569
4833
1.23
4.36
3.3
2.8
—
—
—
0
0
87
544
1.62
4.35
3.5
1.9
7.72
4.25
iu/l
1.48
46
201
1058
9537
1.19
4.31
7.1
6.3
2.84
2.84
%
0.01
1006
8999
738
6442
1.21
4.28
1.9
1.8
99.72
96.97
pmol/l
0.85
400
3480
306
2426
1.30
4.21
2.1
1.9
—
—
—
0
0
195
1447
1.38
4.20
9.2
8.3
7.62
7.72
mmol/l
0.09
184
1394
209
1570
1.36
4.18
3.1
2.6
0.22
0.22
g/l
0.49
198
1482
1102
9989
1.18
4.17
7.1
6.3
29.89
29.88
%
0.01
1049
9473
88
559
1.60
4.14
9.0
5.6
1.88
1.65
%
0.97
82
520
324
2597
1.28
4.10
2.3
2.3
13.76
14.21
umol/l
0.53
307
2418
318
2543
1.29
4.10
1.7
1.7
1147.63
1165.63
nmol/l
0.14
247
1967
568
4855
1.22
4.06
3.5
2.9
0.50
0.37
e6/l
0.53
435
3599
2144
20657
1.26
4.04
13.6
11.1
21.86
21.02
mg/l
0.56
1682
15810
1150
10480
1.18
4.04
7.8
6.5
0.19
0.19
e9/l
0.19
1046
9316
423
3507
1.25
4.03
1.5
1.5
20.43
20.37
nmol/l
0.03
384
3080
671
5834
1.21
4.02
2.4
2.2
—
—
—
0
0
496
4185
1.23
4.02
3.8
3.4
1.02
1.02
kg/l
0.04
73
616
216
1642
1.35
4.00
3.1
3.3
1.69
1.72
%
0.20
194
1487
87
557
1.58
3.98
9.0
5.6
0.93
0.91
%
0.12
81
521
50
275
1.83
3.97
1.5
1.5
—
—
—
0
0
182
1349
1.38
3.97
3.8
3.2
4.38
4.62
pmol/l
3.36
170
1200
1060
9607
1.18
3.95
7.4
6.6
8.36
8.26
%
0.48
1006
9088
81
511
1.60
3.94
3.0
3.0
—
—
—
0
0
516
4384
1.22
3.91
4.0
3.9
13.15
9.48
mg/mmol
0.54
334
2832
1018
9204
1.18
3.89
7.3
6.4
0.68
0.67
%
0.03
961
8663
1962
18753
1.21
3.83
5.3
4.5
1.74
1.97
mu/l
1.32
1859
17634
493
4181
1.22
3.79
3.3
3.4
768.96
359.71
mg/l
0.76
321
2729
64
384
1.68
3.79
3.3
3.1
36.51
33.07
umol/l
0.71
59
356
77
489
1.59
3.67
1.5
1.4
285.13
310.78
ug/g
0.41
39
262
335
2742
1.26
3.57
3.4
2.7
4.31
3.14
e6/l
0.60
192
1409
639
5587
1.19
3.55
2.8
2.5
54.18
57.13
u/l
1.24
589
5214
202
1550
1.33
3.54
2.3
3.0
10.75
10.30
g/l
0.93
190
1426
515
4416
1.21
3.53
2.1
1.9
0.98
1.05
mg/l
0.30
404
3228
406
3399
1.23
3.53
3.1
2.7
560.44
547.01
mosm/kgh2o
0.48
351
2935
731
6477
1.18
3.47
4.1
3.4
60.71
68.15
e6/l
0.19
518
4326
76
488
1.57
3.47
10.0
6.3
1.36
1.25
mmol/l
0.29
66
425
293
2372
1.27
3.43
2.3
2.3
2.46
2.42
g/l
0.40
272
2200
17
64
2.67
3.39
1.1
1.6
—
—
—
0
0
426
3600
1.22
3.38
2.7
2.4
7.76
7.10
e6/l
0.32
382
3225
32
163
1.98
3.24
3.1
3.4
—
—
—
0
0
107
751
1.44
3.23
12.8
11.6
24.51
24.23
mmol/l
0.47
100
734
182
1396
1.33
3.22
9.2
8.2
1.36
1.39
mmol/l
0.16
176
1358
277
2248
1.26
3.19
1.8
1.6
—
—
—
0
0
74
483
1.55
3.18
3.8
2.5
225.79
369.35
ug/l
0.67
69
444
19
79
2.42
3.13
1.7
1.7
—
—
—
0
0
335
2784
1.23
3.12
2.8
2.7
2.42
2.43
mmol/l
0.52
285
2431
345
2879
1.23
3.09
1.3
1.4
500.59
551.61
titre
0.18
68
558
1935
18577
1.18
3.09
3.9
3.7
5.73
5.74
mmol/l
0.14
1809
17320
54
329
1.66
3.08
12.9
7.7
12.00
11.54
mmol/l
0.39
48
296
54
330
1.65
3.05
12.9
7.7
104.92
105.36
mmol/l
0.23
48
297
662
5873
1.17
3.05
3.1
2.9
22.68
45.87
ng/l
1.72
355
3232
12
36
3.34
3.01
3.3
2.5
—
—
—
0
0
414
3531
1.21
2.99
2.7
3.0
1440.31
974.69
ng/l
0.64
343
2917
266
2170
1.25
2.94
2.4
2.4
22.56
23.96
%
1.07
229
1880
153
1164
1.33
2.89
2.7
3.1
69.92
72.17
e9/l
0.26
103
847
1237
11533
1.14
2.83
10.4
9.0
3.97
3.95
e9/l
0.12
1108
10097
511
4464
1.18
2.82
2.3
2.2
2.66
2.78
mg/l
0.70
443
3870
293
2428
1.23
2.82
1.2
1.2
—
—
—
0
0
42
246
1.72
2.80
1.5
1.6
—
—
—
0
0
18
78
2.32
2.74
1.7
1.4
—
—
—
0
0
85
592
1.45
2.72
2.2
2.0
1.36
1.43
g/l
0.33
69
526
1782
17057
1.15
2.71
4.8
4.5
37.86
38.40
mmol/mol
1.85
1684
16138
1520
14391
1.14
2.71
4.3
3.8
10.02
9.79
mm/h
0.29
1436
13482
10
29
3.46
2.69
1.5
1.4
—
—
—
0
0
301
2519
1.22
2.64
2.6
2.6
30.34
29.76
s
0.68
289
2440
119
885
1.36
2.63
9.5
5.2
—
—
—
0
0
2229
21767
1.22
2.47
10.4
8.8
26.34
26.84
u/l
0.66
2169
21133
11
38
2.90
2.41
19.9
10.1
—
—
—
0
0
114
857
1.35
2.38
13.3
7.2
24.50
24.55
mmol/l
0.05
108
811
0
60
0.00
2.24
0.0
1.5
—
—
—
0
0
10
35
2.86
2.20
2.1
1.3
—
—
—
0
0
73
519
1.42
2.16
3.8
2.1
3.46
2.08
ug/l
0.31
58
465
154
1227
1.27
2.14
6.2
4.5
5.18
5.12
kpa
0.55
147
1171
171
1382
1.25
2.11
1.9
2.6
4.78
5.39
e9/l
0.35
146
1195
152
1215
1.27
2.07
6.3
4.5
7.41
7.41
ph
0.08
13
117
64
449
1.44
2.05
2.2
2.0
9.51
10.29
g/l
0.90
59
409
404
3558
1.16
2.01
1.3
1.3
27.63
24.90
iu/ml
0.21
129
1100
1033
9672
1.12
1.97
3.0
2.8
96.74
92.51
ug/l
0.33
970
9123
20
105
1.91
1.95
3.2
3.3
772.75
973.99
u/ml
0.36
20
105
22
120
1.84
1.92
1.3
1.2
—
—
—
0
0
494
4431
1.14
1.91
2.3
2.2
—
—
—
0
0
121
952
1.28
1.89
6.8
4.6
—
—
—
0
0
48
324
1.49
1.89
5.1
5.5
425.42
373.07
umol/l
1.47
43
284
206
1722
1.21
1.89
2.4
2.5
29.56
66.30
u/l
0.73
173
1472
52
358
1.46
1.86
1.3
1.3
3.41
4.89
u/ml
0.57
27
158
551
4988
1.13
1.85
4.1
3.5
0.00
0.00
estimate
1.28
180
1790
1513
14496
1.11
1.82
3.5
3.0
39.67
40.67
u/l
0.25
1443
13822
51
355
1.45
1.74
2.1
2.2
133.17
132.79
g/l
0.03
36
264
134
1080
1.25
1.74
2.5
2.7
67.13
67.04
g/l
0.05
126
1006
112
884
1.28
1.73
7.5
4.8
24.46
24.49
mmol/l
0.04
104
847
21
119
1.77
1.66
1.0
1.1
1549.43
1518.71
miu/ml
0.03
21
119
50
351
1.43
1.65
4.4
5.0
—
—
—
0
0
156
1291
1.22
1.61
1.2
1.2
55.00
130.88
titre
—
6
34
1945
18942
1.12
1.59
17.9
13.9
333.59
333.49
g/l
0.19
1939
18799
1916
18652
1.12
1.55
3.5
3.4
1.25
1.28
mmol/l
1.10
1808
17586
80
614
1.31
1.55
8.7
7.8
1.30
1.28
mg/l
0.10
75
585
246
2132
1.17
1.54
3.3
3.1
7.95
7.12
umol/l
0.25
217
1825
21
122
1.73
1.54
3.4
3.9
—
—
—
0
0
148
1226
1.22
1.53
1.4
1.4
—
—
—
0
0
2219
21808
1.15
1.49
12.2
10.0
—
—
—
0
0
15
80
1.88
1.44
3.1
2.7
100.78
111.11
ng/l
—
9
59
63
828
0.75
1.42
1.5
1.4
—
—
—
0
0
65
849
0.76
1.40
1.5
1.5
—
—
—
0
0
122
1001
1.23
1.40
1.1
1.1
—
—
—
0
0
228
1983
1.16
1.39
1.4
1.3
—
—
—
0
0
81
636
1.28
1.36
3.6
4.2
0.31
0.32
g/l
0.02
37
314
51
375
1.37
1.34
1.5
1.7
9072.39
12567.99
e6/l
0.43
44
280
16
90
1.78
1.33
2.2
1.3
—
—
—
0
0
19
113
1.69
1.31
4.4
3.2
138.21
151.44
umol/l
0.13
14
66
70
542
1.30
1.31
1.3
1.4
96.00
85.64
titre
—
5
55
51
378
1.36
1.29
2.0
2.0
39.29
38.30
g/l
0.55
46
339
2381
23564
1.21
1.28
20.0
16.3
259.65
259.73
e9/l
0.02
2338
23016
64
825
0.77
1.28
1.5
1.4
—
—
—
0
0
27
178
1.52
1.26
1.1
1.3
—
196.25
—
0
8
46
620
0.74
1.26
1.0
1.1
3.53
1.28
u/ml
0.33
13
307
35
244
1.44
1.25
1.1
1.2
—
43.51
—
0
15
2383
23591
1.20
1.24
20.0
16.3
6.71
6.71
e9/l
0.01
2338
22994
131
1554
0.83
1.24
1.5
1.6
—
—
—
0
0
22
139
1.59
1.23
1.2
1.2
1.06
1.05
ratio
—
7
57
16
93
1.73
1.21
2.2
1.3
—
—
—
0
0
143
1214
1.19
1.19
1.9
1.9
1.40
1.33
g/l
0.16
138
1129
51
384
1.33
1.18
1.1
1.2
—
—
—
0
0
2382
23588
1.20
1.18
19.9
16.2
89.90
89.90
fl
0.01
2362
23324
1989
19484
1.10
1.18
3.9
3.7
4.70
4.75
mmol/l
1.52
1891
18525
139
1179
1.19
1.18
2.8
2.5
—
—
—
0
0
2382
23589
1.20
1.18
19.9
16.2
30.05
30.06
pg
0.01
2361
23325
8
39
2.05
1.15
1.0
1.2
—
—
—
0
0
5
20
2.50
1.15
1.0
4.2
—
—
—
0
0
46
610
0.75
1.15
1.0
1.1
5.79
1.78
u/ml
0.74
18
338
368
3351
1.12
1.15
1.7
1.6
40752801.58
30988298.28
pmol/l
0.13
319
2885
49
369
1.33
1.14
3.8
3.1
26.05
21.39
mg/l
0.30
29
233
22
142
1.55
1.14
1.2
1.2
—
—
—
0
0
2382
23594
1.19
1.14
19.9
16.2
4.57
4.57
e12/l
0.14
2335
23005
156
1341
1.17
1.14
1.3
1.3
44.50
46.68
au/ml
—
7
76
1889
18474
1.09
1.12
16.9
13.4
14.23
14.29
%
0.18
1857
18158
11
58
1.90
1.12
1.5
1.1
15.91
11.98
u/l
0.32
11
52
11
58
1.90
1.12
2.7
2.1
15.03
16.52
umol/l
0.27
11
58
129
1093
1.19
1.12
2.9
3.3
—
—
—
0
0
34
243
1.40
1.09
1.2
1.5
73.63
67.74
mmol/l
0.21
27
202
167
1450
1.16
1.09
2.3
2.3
19.23
22.98
au/ml
—
9
147
16
97
1.65
1.06
1.4
1.3
202.19
380.60
u/l
0.80
16
86
2382
23605
1.18
1.06
20.1
16.3
136.68
136.71
g/l
0.04
2363
23337
2005
19677
1.09
1.06
4.2
4.0
2.85
2.86
mmol/l
0.19
1896
18586
254
2276
1.13
1.05
1.2
1.2
—
—
—
0
0
60
473
1.28
1.03
1.4
1.5
95.35
112.03
u/ml
0.66
13
87
5
22
2.28
1.03
1.0
1.2
—
—
—
0
0
5
22
2.28
1.03
1.2
1.8
—
—
—
0
0
278
2509
1.12
1.03
1.8
1.8
—
—
—
0
0
11
60
1.84
1.02
6.6
7.3
20.15
104.00
g/mol
1.30
11
54
2376
23548
1.17
1.01
20.3
16.3
40.71
40.98
%
0.41
2242
22387
1974
19379
1.09
0.98
3.8
3.7
1.44
1.46
mmol/l
1.28
1871
18343
588
5523
1.08
0.97
3.3
2.8
—
—
—
0
0
49
380
1.30
0.97
1.6
1.8
0.55
0.80
g/l
1.89
39
292
947
9060
1.07
0.96
9.9
8.7
0.01
0.00
e9/l
0.52
776
7373
83
686
1.22
0.96
2.8
3.2
—
—
—
0
0
762
8017
0.93
0.96
2.5
2.4
—
—
—
0
0
62
497
1.25
0.95
1.3
1.5
—
—
—
0
0
0
32
0.00
0.95
0.0
1.8
—
—
—
0
0
9
51
1.77
0.94
1.1
1.0
4.03
7.71
mg/g
—
9
51
117
1001
1.18
0.94
1.1
1.1
—
—
—
0
0
26
183
1.43
0.93
2.4
3.2
—
—
—
0
0
6
120
0.50
0.93
1.0
1.3
—
—
—
0
0
13
78
1.67
0.91
1.2
1.3
—
—
—
0
0
69
565
1.23
0.89
7.3
4.8
—
—
—
0
0
113
1312
0.85
0.89
1.5
1.4
—
—
—
0
0
366
3384
1.10
0.88
1.2
1.2
11.31
9.59
u/ml
0.17
130
1394
6
30
2.00
0.87
2.8
2.1
—
—
—
0
0
52
648
0.80
0.86
1.0
1.1
5.88
6.49
u/ml
0.12
27
376
536
5042
1.08
0.86
7.6
7.0
—
—
—
0
0
32
423
0.75
0.84
1.0
1.1
0.11
0.37
u/ml
—
6
135
173
1540
1.13
0.84
2.9
2.3
5921.55
6358.81
u/l
0.06
68
590
511
4804
1.08
0.83
1.7
1.6
1.31
1.39
mmol/l
1.49
447
4190
10
57
1.76
0.83
1.3
3.1
85.47
87.04
ug/l
—
10
57
11
65
1.70
0.82
1.5
2.0
—
—
—
0
0
327
3020
1.10
0.81
2.8
2.6
104.94
112.35
ug/g
0.16
271
2416
8
47
1.70
0.80
1.4
1.2
—
—
—
0
0
44
347
1.27
0.80
2.7
3.5
34.89
66.14
mg/l
0.96
38
274
44
347
1.27
0.80
2.7
3.5
24.29
31.34
mg/l
1.69
38
274
48
383
1.26
0.80
2.3
1.5
—
—
—
0
0
583
5521
1.07
0.79
1.4
1.3
1.53
1.89
u/ml
0.47
160
1459
26
349
0.74
0.77
1.3
1.6
—
—
—
0
0
669
6371
1.07
0.77
1.5
1.6
—
—
—
0
0
338
3136
1.09
0.77
1.6
1.6
—
—
—
0
0
22
157
1.40
0.76
1.7
1.5
—
—
—
0
0
30
226
1.33
0.76
1.4
1.3
—
—
—
0
0
10
59
1.70
0.75
3.0
3.0
—
—
—
0
0
89
762
1.17
0.75
1.3
1.6
—
9.14
u/ml
—
0
25
474
4463
1.08
0.75
2.6
2.4
332.59
4035.74
umol/l
9.94
431
4022
66
551
1.20
0.74
1.1
1.2
—
—
—
0
0
41
325
1.27
0.73
3.6
3.9
—
—
—
0
0
33
254
1.30
0.73
1.3
1.4
—
—
—
0
0
325
3495
0.92
0.73
1.4
1.5
—
—
—
0
0
58
479
1.22
0.73
1.5
1.3
—
6.59
—
0
8
93
803
1.16
0.72
1.1
1.2
0.25
1.07
u/ml
—
6
68
34
264
1.29
0.71
2.9
3.7
—
—
—
0
0
7
40
1.75
0.71
1.3
1.1
—
—
—
0
0
36
454
0.79
0.69
1.3
1.3
—
—
—
0
0
9
144
0.62
0.69
1.2
1.3
65.89
75.42
umol/l
—
9
144
39
310
1.26
0.69
2.4
2.5
—
—
—
0
0
19
135
1.41
0.69
2.1
1.6
16.19
25.02
umol/l
1.05
19
128
27
204
1.33
0.69
2.7
3.1
—
—
—
0
0
168
1516
1.12
0.68
3.9
3.8
—
—
—
0
0
12
77
1.56
0.68
5.0
2.6
—
—
—
0
0
12
77
1.56
0.68
2.7
4.7
—
—
—
0
0
5
27
1.85
0.68
1.2
1.3
—
—
—
0
0
5
27
1.85
0.68
1.4
1.2
1.64
1.77
umol/24h
—
5
27
36
284
1.27
0.68
3.2
3.3
14.51
61.04
u/ml
0.54
36
279
10
156
0.64
0.67
1.0
1.2
—
—
—
0
0
790
7598
1.06
0.66
2.0
1.9
—
—
—
0
0
58
690
0.84
0.66
1.1
1.1
5.06
2.97
u/ml
0.26
27
380
32
250
1.28
0.65
1.5
1.3
—
0.42
nmol/l
—
0
13
169
1531
1.11
0.65
2.4
2.2
12.55
12.50
nmol/l
0.03
159
1391
15
103
1.46
0.65
2.1
1.4
—
—
—
0
0
17
120
1.42
0.64
1.2
1.1
—
—
—
0
0
54
450
1.20
0.64
4.0
2.5
7.38
6.13
umol/l
0.22
37
345
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
219
2015
1.10
0.63
1.3
1.5
—
—
—
0
0
6
102
0.59
0.62
5.3
5.9
—
—
—
0
0
6
102
0.59
0.62
2.7
3.0
—
—
—
0
0
240
2222
1.09
0.60
1.6
1.5
—
—
—
0
0
169
1539
1.11
0.60
1.6
1.4
26.14
23.97
iu/l
0.38
135
1271
98
864
1.14
0.60
2.6
2.2
—
—
—
0
0
32
254
1.26
0.59
1.0
1.1
—
—
—
0
0
8
53
1.51
0.58
2.5
2.4
—
—
—
0
0
38
309
1.23
0.58
3.9
2.8
—
—
—
0
0
6
35
1.72
0.57
1.5
1.5
—
—
—
0
0
188
1728
1.10
0.56
1.2
1.2
144.83
149.80
iu/ml
0.07
79
646
6
36
1.67
0.56
1.2
1.2
—
—
—
0
0
6
36
1.67
0.56
1.2
1.2
—
—
—
0
0
6
36
1.67
0.56
1.2
1.2
—
—
—
0
0
158
1730
0.91
0.56
1.2
1.3
—
—
—
0
0
240
2232
1.08
0.55
1.3
1.4
—
—
—
0
0
41
492
0.83
0.54
1.0
1.1
2.69
4.86
u/ml
1.17
17
246
35
285
1.23
0.54
1.2
1.2
—
—
—
0
0
12
170
0.70
0.53
3.4
3.2
—
—
—
0
0
32
393
0.81
0.53
1.2
1.1
—
—
—
0
0
122
1102
1.11
0.53
2.2
2.2
7.16
7.41
ug/l
0.05
106
989
20
152
1.32
0.52
1.4
1.4
3259.15
85750.12
e6/l
1.09
13
102
12
83
1.45
0.51
1.4
1.3
—
—
—
0
0
6
100
0.60
0.51
1.2
1.4
183.83
162.36
mmol/24h
—
6
100
16
118
1.36
0.50
1.9
2.3
—
—
—
0
0
102
916
1.12
0.50
1.9
1.5
9.00
8.72
u/l
0.09
83
714
216
2014
1.08
0.49
1.2
1.2
—
—
—
0
0
7
45
1.56
0.49
1.7
1.6
—
—
—
0
0
86
766
1.13
0.48
3.7
2.9
—
—
—
0
0
80
711
1.13
0.47
1.2
1.1
6.26
4.50
u/ml
—
9
112
501
4808
1.05
0.47
1.6
1.5
2.22
2.18
g/l
0.17
316
2969
45
383
1.18
0.46
1.1
1.1
—
—
—
0
0
89
798
1.12
0.46
1.3
1.3
—
—
—
0
0
18
138
1.31
0.45
1.3
1.2
—
65.52
—
0
12
18
138
1.31
0.45
4.0
3.1
44916.67
40475.71
ug/l
0.60
18
138
15
198
0.76
0.45
2.9
3.9
—
—
—
0
0
19
147
1.29
0.45
1.2
1.3
—
—
—
0
0
7
50
1.40
0.45
1.4
1.4
—
—
—
0
0
453
4342
1.05
0.44
3.5
3.1
—
—
—
0
0
199
2129
0.93
0.44
2.4
2.5
0.52
0.70
ug/l
3.40
102
1156
36
427
0.84
0.44
1.2
2.4
1.02
0.82
nmol/l
1.19
31
370
31
256
1.21
0.44
2.6
2.6
—
—
—
0
0
136
1251
1.09
0.44
1.3
1.2
—
—
—
0
0
281
2968
0.94
0.43
1.3
1.3
—
—
—
0
0
23
184
1.25
0.43
1.2
1.1
—
—
—
0
0
10
140
0.71
0.43
2.0
2.9
—
—
—
0
0
150
1387
1.09
0.43
5.3
4.5
0.06
0.58
%
0.93
35
354
5
31
1.61
0.43
1.0
6.6
—
—
—
0
0
30
360
0.83
0.42
4.7
3.7
2.06
2.33
mmol/l
0.24
16
220
31
370
0.84
0.41
1.3
1.1
113.29
1237.60
iu/ml
—
7
113
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
17
0.00
0.40
0.0
2.1
—
3.69
—
0
7
25
303
0.82
0.39
1.7
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
57.90
—
0
5
55
485
1.14
0.38
7.4
4.1
1.29
1.39
mmol/l
0.42
55
477
9
68
1.32
0.37
2.0
2.1
—
208.18
—
0
10
22
179
1.23
0.37
1.2
1.6
44.27
56.52
%
0.63
11
120
21
170
1.24
0.37
1.1
1.3
0.26
3.62
u/ml
2.54
13
90
138
1283
1.08
0.37
3.4
3.2
—
—
—
0
0
16
125
1.28
0.37
1.3
1.5
36.81
32.48
%
—
10
80
56
497
1.13
0.36
2.8
3.6
250.24
860.26
u/ml
0.82
45
421
9
124
0.72
0.35
1.1
1.2
—
—
—
0
0
167
1570
1.07
0.34
1.5
1.3
226.39
221.02
u/ml
0.04
156
1463
43
377
1.14
0.34
1.1
1.1
—
—
—
0
0
15
188
0.80
0.33
1.3
1.4
—
—
—
0
0
42
477
0.88
0.33
1.6
1.5
0.30
0.42
nmol/l
0.88
35
382
6
90
0.67
0.32
1.0
1.1
—
—
—
0
0
141
1321
1.07
0.32
3.4
4.2
5.10
18.85
ug/l
1.79
114
1024
10
74
1.35
0.32
1.2
1.5
81.80
93.13
nmol/24h
—
10
74
10
74
1.35
0.32
1.0
1.0
800.40
768.31
ng/l
—
5
48
24
202
1.19
0.31
1.1
1.2
0.37
3.25
u/ml
1.44
12
88
7
55
1.27
0.30
1.1
1.8
—
—
—
0
0
32
278
1.15
0.29
3.1
2.7
1.47
1.56
mmol/l
0.17
32
270
40
450
0.89
0.28
1.1
1.1
8.21
5.63
u/ml
0.26
18
197
12
151
0.79
0.28
1.2
1.3
1.47
1.56
g/l
0.65
12
151
28
242
1.16
0.28
1.5
1.4
0.43
0.37
g/l
0.35
22
172
28
242
1.16
0.28
1.5
1.4
2.49
2.81
g/l
0.46
22
174
28
243
1.15
0.27
1.5
1.4
6.84
6.65
g/l
0.09
21
175
28
243
1.15
0.27
1.5
1.4
—
—
—
0
0
151
1433
1.06
0.25
1.4
1.4
—
—
—
0
0
68
627
1.09
0.25
1.7
1.8
0.23
0.23
g/l
0.21
62
587
50
454
1.10
0.25
1.1
1.1
—
—
—
0
0
111
1044
1.07
0.25
1.3
1.3
181.50
230.60
miu/ml
1.03
54
521
168
1602
1.05
0.24
2.3
2.3
—
—
—
0
0
169
1612
1.05
0.24
2.1
2.2
—
—
—
0
0
51
465
1.10
0.24
2.8
2.1
—
—
—
0
0
25
218
1.15
0.23
1.4
1.3
—
—
—
0
0
133
1263
1.06
0.23
2.4
2.4
—
—
—
0
0
70
650
1.08
0.23
1.1
1.2
—
—
—
0
0
169
1616
1.05
0.22
2.4
2.3
—
—
—
0
0
14
168
0.83
0.22
2.4
2.8
0.86
0.84
nmol/l
0.04
14
124
16
189
0.85
0.22
1.0
1.1
1.19
4.99
u/ml
—
7
56
26
294
0.88
0.21
4.7
3.7
82.96
29.00
u/ml
0.65
26
286
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
9.0
—
67.80
—
0
5
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
0.10
—
0
5
0
12
0.00
0.21
0.0
1.0
—
3106.00
—
0
7
0
12
0.00
0.21
0.0
1.1
—
0.20
—
0
5
160
1532
1.05
0.21
5.1
4.4
0.88
0.94
%
0.11
45
501
33
366
0.90
0.20
2.0
2.4
20.92
113.69
ug/min
3.49
16
234
10
80
1.25
0.20
1.5
1.5
—
—
—
0
0
6
48
1.25
0.20
1.3
1.2
—
—
—
0
0
6
48
1.25
0.20
1.3
1.2
—
—
—
0
0
6
48
1.25
0.20
1.3
1.2
—
—
—
0
0
15
176
0.85
0.20
4.1
2.9
3.27
34.94
nmol/l
0.50
15
170
40
365
1.10
0.19
1.6
1.8
—
—
—
0
0
17
146
1.17
0.19
1.1
1.0
—
—
—
0
0
19
165
1.15
0.19
3.2
2.2
—
—
—
0
0
6
53
1.13
0.18
2.7
1.8
—
—
—
0
0
6
53
1.13
0.18
1.0
1.3
17.77
17.54
umol/l
—
6
47
12
143
0.84
0.18
3.2
2.7
60.83
54.11
%
—
6
131
22
194
1.14
0.18
1.5
1.3
40.09
32.32
nmol/l
0.49
22
168
189
1956
0.96
0.18
3.7
3.7
31.74
31.52
%
0.10
145
1456
15
174
0.86
0.17
1.1
1.0
—
—
—
0
0
69
649
1.06
0.17
1.7
1.8
1.18
1.17
g/l
0.05
63
608
162
1681
0.96
0.17
4.2
3.5
—
—
—
0
0
5
67
0.75
0.17
2.0
1.2
—
—
—
0
0
15
129
1.16
0.17
1.1
1.0
—
—
—
0
0
83
787
1.06
0.17
2.4
2.3
—
—
—
0
0
372
3639
1.03
0.17
3.5
3.7
1.90
1.95
ug/l
0.04
341
3319
28
309
0.91
0.17
2.8
2.4
17.19
16.73
%
0.18
16
154
20
177
1.13
0.16
1.2
1.2
—
—
—
0
0
11
92
1.20
0.16
1.5
1.6
—
—
—
0
0
13
151
0.86
0.15
1.0
1.2
—
—
—
0
0
38
411
0.92
0.15
1.2
1.2
—
—
—
0
0
8
73
1.10
0.15
1.0
1.0
—
—
—
0
0
37
342
1.08
0.15
4.5
3.5
—
—
—
0
0
31
284
1.09
0.15
1.4
1.6
—
—
—
0
0
9
83
1.08
0.14
1.0
1.2
1.26
4.58
u/ml
—
9
72
25
227
1.10
0.14
1.4
1.3
—
—
nmol/l
—
0
0
10
118
0.85
0.14
1.0
1.4
—
—
—
0
0
164
1590
1.03
0.14
2.2
2.3
—
—
—
0
0
67
636
1.05
0.14
1.3
1.2
—
—
—
0
0
10
84
1.19
0.14
1.0
1.0
—
—
—
0
0
13
149
0.87
0.13
2.2
2.4
—
—
—
0
0
19
170
1.12
0.13
1.2
1.1
—
—
—
0
0
17
151
1.13
0.13
1.1
1.1
—
—
—
0
0
9
107
0.84
0.13
4.2
3.9
1.25
1.54
ug/l
—
9
100
15
169
0.89
0.12
1.1
1.1
—
—
—
0
0
10
85
1.18
0.12
1.1
1.1
—
—
—
0
0
20
181
1.11
0.12
1.3
1.2
—
—
—
0
0
75
718
1.05
0.12
1.2
1.2
—
—
—
0
0
145
1408
1.03
0.12
5.1
4.2
0.66
0.63
%
0.07
37
439
19
209
0.91
0.11
1.1
1.2
1.38
11.37
u/ml
—
6
76
22
239
0.92
0.10
2.8
3.2
1.38
1.39
%
0.00
17
223
124
1276
0.97
0.10
3.8
3.5
1.23
1.23
mmol/l
0.16
112
1101
150
1462
1.03
0.10
5.3
4.5
0.17
0.12
%
0.20
35
429
125
1215
1.03
0.10
2.1
1.6
346.96
293.38
mu/l
1.02
111
1093
52
496
1.05
0.10
1.1
1.1
—
—
—
0
0
5
44
1.14
0.10
5.0
7.2
—
—
—
0
0
5
45
1.11
0.09
1.6
2.1
—
—
—
0
0
133
1296
1.03
0.09
1.2
1.2
—
—
—
0
0
13
145
0.90
0.09
3.0
2.8
2.52
1.80
g/24h
—
6
84
360
3645
0.99
0.08
1.7
1.7
—
—
—
0
0
5
61
0.82
0.08
2.2
2.1
3.56
3.35
ug/l
—
5
55
5
61
0.82
0.08
2.8
2.1
2.40
2.15
ug/l
—
5
53
589
5942
0.99
0.08
2.0
2.0
—
—
—
0
0
14
154
0.91
0.08
1.4
1.1
—
—
—
0
0
15
164
0.91
0.08
1.6
1.6
—
—
—
0
0
6
73
0.82
0.07
4.2
2.1
—
—
—
0
0
6
73
0.82
0.07
1.0
2.6
—
—
—
0
0
16
147
1.09
0.07
3.3
7.1
12.33
11.43
%
0.51
16
147
48
499
0.96
0.07
1.7
1.3
—
—
—
0
0
152
1492
1.02
0.07
2.4
2.4
—
—
—
0
0
9
86
1.05
0.07
2.7
3.2
—
—
—
0
0
9
102
0.88
0.06
1.1
1.1
—
—
—
0
0
9
105
0.86
0.06
1.1
1.2
—
—
—
0
0
39
375
1.04
0.05
4.2
3.9
58.05
56.09
%
0.58
39
375
39
405
0.96
0.05
1.2
1.0
5.34
3.37
u/ml
0.29
17
213
38
366
1.04
0.05
3.8
3.6
3.74
3.96
e9/l
0.41
38
366
30
287
1.05
0.05
1.5
1.4
—
—
—
0
0
19
179
1.06
0.05
1.2
1.4
167.96
220.66
pmol/l
0.45
19
179
51
496
1.03
0.04
1.1
1.1
—
—
—
0
0
15
140
1.07
0.04
1.1
1.0
—
—
—
0
0
84
824
1.02
0.04
1.8
1.7
—
—
—
0
0
16
150
1.07
0.04
1.3
1.1
—
—
—
0
0
10
109
0.92
0.04
11.6
6.5
—
—
—
0
0
42
411
1.02
0.02
2.1
2.4
—
—
—
0
0
473
4723
1.00
0.00
1.7
1.7
—
—
—
0
0
16
165
0.97
0.00
1.2
1.1
—
—
—
0
0
10
99
1.01
0.00
1.1
1.1
124.20
239.24
iu/ml
—
10
99
20
201
0.99
0.00
6.1
4.1
477.23
94.63
u/ml
—
9
58
80
805
0.99
0.00
1.6
1.6
—
—
—
0
0
60
599
1.00
0.00
8.5
8.7
—
—
—
0
0
17
174
0.98
0.00
13.8
12.0
0.66
0.61
mmol/l
0.79
17
158
10
102
0.98
0.00
1.0
1.5
133.58
137.01
nmol/l
—
10
102
12
118
1.02
0.00
2.0
2.3
790.50
607.71
ml
—
6
83
105
1046
1.00
0.00
1.3
1.3
—
—
—
0
0
57
572
1.00
0.00
1.2
1.3
205.95
237.72
u/ml
0.69
39
338
0
7
0.00
0.00
0.0
1.3
—
32.69
—
0
7
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
6
65
0.92
-0.00
1.0
2.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
198.56
—
0
8
6
69
0.87
-0.00
1.0
1.1
—
—
—
0
0
15
150
1.00
-0.00
1.6
2.2
—
—
—
0
0
24
240
1.00
-0.00
2.0
1.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
5.2
—
435.33
—
0
9
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
8.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
1500.83
—
0
6
0
8
0.00
-0.00
0.0
1.4
—
67.45
—
0
8
8
88
0.91
-0.00
1.1
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
1.2
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
4.33
—
0
9
0
6
0.00
-0.00
0.0
1.3
—
2.47
—
0
6
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_CONVERSTRAB and mortality.

Females

Parameter HR [95% CI] p-value
H7_CONVERSTRAB 1.266 [1.03, 1.56] 0.027
Birth year 0.993 [0.98, 1.0] 0.115

During the follow-up period (1.1.1998 — 31.12.2019), 231 out of 8389 females with H7_CONVERSTRAB died.

Males

Parameter HR [95% CI] p-value
H7_CONVERSTRAB 1.261 [1.02, 1.56] 0.03
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 237 out of 7962 males with H7_CONVERSTRAB died.

Mortality risk

Mortality risk for people of age

years, who have H7_CONVERSTRAB.

N-year risk Females Males
1 0.12% 0.25%
5 0.741% 1.622%
10 1.733% 3.733%
15 3.213% 7.03%
20 5.683% 11.43%

Relationships between endpoints

Index endpoint: H7_CONVERSTRAB – Convergent concomitant strabismus

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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