gout: A condition characterized by painful swelling of the joints, which is caused by deposition of urate crystals.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
379 |
4. Check minimum number of eventsNone |
379 |
5. Include endpointsNone |
379 |
6. Filter based on genotype QC (FinnGen only) |
365 |
Control definitions (FinnGen only)
- Control exclude
- GOUT
Extra metadata
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M10
- Name in latin
- Arthritis urica ex insufficientia renali
Gout due to impairment of renal function
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1900 | 646 | 1244 |
| Only index persons | 1736 | 586 | 1150 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.02 | 0.03 |
| Only index persons | 0.04 | 0.02 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 73.96 | 77.27 | 72.23 |
| Only index persons | 73.66 | 76.82 | 72.05 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 365 | 97 | 268 |
| Unadjusted period prevalence (%) | 0.10 | 0.03 | 0.12 |
| Median age at first event (years) | 71.33 | 73.75 | 70.45 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 379
- Matched controls
- 3790
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
90.8
312.6
171
34
M10.9
ICD-10 Finland
Gout, unspecified
59.3
307.7
209
77
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
98.1
307.7
181
35
M10.3
ICD-10 Finland
Gout due to impairment of renal function
+∞
307.7
379
*
M04AA01
ATC
allopurinol; systemic
94.5
307.7
338
304
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
55.5
307.7
256
137
A11CC03
ATC
alfacalcidol; systemic
83.4
294.3
163
34
N18.8
ICD-10 Finland
Other chronic renal failure
79.8
285.3
159
34
A12AA04
ATC
calcium carbonate; oral
95.4
231.7
123
19
TK800
NOMESCO Finland
Hemodialysis
46.2
197.6
123
39
N18.0
ICD-10 Finland
End-stage renal disease
108.6
175.8
91
11
B03XA02
ATC
darbepoetin alfa; parenteral
41.9
161.7
102
33
L04AA06
ATC
mycophenolic acid; systemic
62.7
160.5
91
19
Z49.1
ICD-10 Finland
Extracorporeal dialysis
51.8
153.7
91
23
127
Kela drug reimbursment
Transplant complication
65.1
153.1
86
17
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
71.7
152.4
84
15
M10.0
ICD-10 Finland
Idiopathic gout
33.0
137.3
93
37
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
81.2
124.6
67
10
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
79.7
122.4
66
10
N19
ICD-10 Finland
Unspecified kidney failure
17.6
116.8
107
83
C03CA01
ATC
furosemide; systemic
14.2
112.4
318
1020
137
Kela drug reimbursment
Uraemia requiring dialysis
72.5
111.4
61
10
V03AE01
ATC
polystyrene sulfonate; oral
45.2
100.9
61
16
205
Kela drug reimbursment
Chronic hypertension
8.0
87.4
264
841
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
11.3
85.0
103
121
N17.9
ICD-10 Finland
Acute renal failure, unspecified
12.9
81.7
88
87
M10
ICD-10 Finland
Gout
15.1
79.4
76
62
Z94.0
ICD-10 Finland
Kidney transplant status
117.7
78.6
83
9
212
Kela drug reimbursment
Gout
+∞
75.6
70
*
L04AD01
ATC
ciclosporin; systemic
28.6
72.4
50
20
N18.4
ICD-10 Finland
Chronic kidney disease, stage 4
41.4
71.5
44
12
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.2
71.1
139
282
C02AC05
ATC
moxonidine; oral
10.2
69.1
88
109
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
145.1
68.5
71
6
I12.0
ICD-10 Finland
Hypertensive renal disease with renal failure
37.2
67.9
43
13
Z49.0
ICD-10 Finland
Preparatory care for dialysis
99.7
67.8
73
9
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
26.0
67.2
48
21
I50.9
ICD-10 Finland
Heart failure, unspecified
5.9
64.0
171
461
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
11.9
63.3
70
71
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
8.4
61.7
93
141
KA1AE
NOMESCO Finland
Kidney ultrasound examination
15.1
60.1
56
43
A46
ICD-10 Finland
Erysipelas
5.8
57.0
142
355
T92
ICPC
Gout
18.6
55.6
46
28
C08CA01
ATC
amlodipine; oral
5.2
50.0
270
1227
H02AB04
ATC
methylprednisolone; systemic
5.5
49.8
127
320
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.5
49.4
122
299
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
146.8
49.1
51
*
I50.0
ICD-10 Finland
Congestive heart failure
6.1
47.8
100
210
H02AB06
ATC
prednisolone; systemic
5.1
47.3
276
1311
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
7.0
47.3
82
143
A10BH05
ATC
linagliptin; oral
7.4
47.1
77
126
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
114.8
47.0
50
5
288
Kela drug reimbursment
Febuxostat
+∞
46.9
44
*
L04AD02
ATC
tacrolimus; systemic
75.0
46.5
52
8
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
5.2
45.1
120
311
C08CA13
ATC
lercanidipine; oral
5.0
45.1
128
350
M13.9
ICD-10 Finland
Arthritis, unspecified
7.4
44.6
72
116
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.6
43.6
148
465
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
8.2
43.3
63
90
196
Kela drug reimbursment
Paricalcitol and cinacalcet
127.3
42.8
45
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.2
42.4
212
879
M04AA03
ATC
febuxostat; oral
+∞
41.4
39
*
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
74.5
41.1
46
7
TPX10
NOMESCO Finland
Implantation of vascular injection port
11.0
40.9
46
47
349
Kela drug reimbursment
Febuxostat
+∞
40.3
38
*
H05BX01
ATC
cinacalcet; oral
96.8
39.7
43
5
C08CA02
ATC
felodipine; oral
5.1
38.7
98
241
C09AA02
ATC
enalapril; systemic
4.1
38.6
158
562
A10AC01
ATC
insulin (human); parenteral
5.7
38.6
83
177
C07AG02
ATC
carvedilol; oral
6.1
38.1
75
147
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
210.5
37.5
38
*
V03AE02
ATC
sevelamer; oral
144.4
37.5
39
*
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
60.4
37.2
43
8
ZX120
NOMESCO Finland
Intravenous
5.3
37.2
89
208
C09CA01
ATC
losartan; oral
3.9
37.2
180
715
U14
ICPC
Kidney symptom/complaint
13.6
37.2
36
29
Z49.2
ICD-10 Finland
Other dialysis
67.2
37.0
42
7
B05DA
ATC
Isotonic solutions
65.4
36.0
41
7
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
57.2
35.2
41
8
B05DB
ATC
Hypertonic solutions
72.2
34.7
39
6
E87.5
ICD-10 Finland
Hyperkalaemia
13.2
34.6
34
28
L04AA01
ATC
[U] ciclosporin
50.9
34.5
41
9
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
4.7
34.2
97
260
TPH04
NOMESCO Finland
Cathetrisation of vein
3.8
34.2
153
571
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.9
33.6
270
1465
B01AA03
ATC
warfarin; systemic
3.7
33.2
161
632
JN3AD
NOMESCO Finland
Abdominal CT examination
4.6
32.4
92
246
321
Kela drug reimbursment
Paricalcitol and cinacalcet
96.2
32.3
35
*
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
96.2
32.3
35
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.6
32.1
92
248
B03XA01
ATC
erythropoietin; parenteral
37.1
31.6
40
12
I10
ICD-10 Finland
Essential (primary) hypertension
5.1
30.6
326
2081
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.4
30.4
181
800
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.5
29.5
64
136
215
Kela drug reimbursment
Diabetes, non-insulin-treated
3.3
28.3
162
693
I50.1
ICD-10 Finland
Left ventricular failure
5.6
28.0
58
118
103
Kela drug reimbursment
Diabetes, insulin-treated
3.2
27.5
178
816
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
10.2
27.4
32
34
R4110
NOMESCO Finland
Physiotherapy
3.3
27.4
164
718
A10AB05
ATC
insulin aspart; parenteral
4.8
27.4
70
171
R50.9
ICD-10 Finland
Fever, unspecified
3.8
27.3
104
342
A10AE04
ATC
insulin glargine; parenteral
4.3
27.0
83
234
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
37.2
27.0
34
10
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
7.2
25.6
40
61
C02CA01
ATC
prazosin; oral
9.6
25.4
31
35
L04AX01
ATC
azathioprine; systemic
7.1
25.3
40
62
B01AB10
ATC
tinzaparin; parenteral
4.3
25.2
74
201
ZXD05
NOMESCO Finland
Urgent procedure
3.1
25.1
165
755
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
6.6
24.8
42
70
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
52.1
24.6
29
6
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
52.1
24.6
29
6
V03AE03
ATC
lanthanum carbonate; oral
60.2
24.4
28
5
C07AB07
ATC
bisoprolol; oral
3.2
24.1
268
1628
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.0
23.6
159
732
WX203
NOMESCO Finland
Infraclavicular plexus blockade
10.3
23.5
27
28
SPAT1262
SPAT
Handing over of treatment supplies
3.3
23.4
117
453
TK820
NOMESCO Finland
Peritoneal dialysis
57.9
23.4
27
5
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
3.7
23.2
88
286
J01FF01
ATC
clindamycin; systemic
3.0
23.1
149
668
D64.9
ICD-10 Finland
Anaemia, unspecified
3.6
22.9
89
294
WW200
NOMESCO Finland
Immunization
8.4
22.9
31
40
N25.0
ICD-10 Finland
Renal osteodystrophy
127.8
22.9
24
*
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
127.8
22.9
24
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
5.2
22.7
51
111
C10AA05
ATC
atorvastatin; oral
2.9
22.6
236
1367
J01DB01
ATC
cefalexin; oral
5.4
22.1
347
2536
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
3.5
21.9
89
302
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.0
21.3
128
548
R60.0
ICD-10 Finland
Localized oedema
3.6
21.1
83
275
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.0
20.9
68
198
R4190
NOMESCO Finland
Nutritional therapy
7.0
20.8
33
51
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
116.5
20.8
22
*
A41.9
ICD-10 Finland
Sepsis, unspecified
6.2
20.7
37
65
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.8
20.6
160
785
Z3231
NOMESCO Finland
Registered nurse
2.8
20.5
153
734
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.8
20.5
154
742
A12BA01
ATC
potassium chloride; oral
5.4
20.5
43
88
J01MA02
ATC
ciprofloxacin; systemic
2.7
20.4
208
1169
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
8.9
20.4
26
31
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.9
20.1
129
571
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.8
20.0
152
735
JN4AD
NOMESCO Finland
Body CT examination
3.6
19.9
75
241
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
7.1
19.9
31
47
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.7
19.8
39
75
3AC01, ,
NOMESCO Finland
26.3
19.8
27
11
TK810
NOMESCO Finland
Hemofiltration
33.3
19.5
25
8
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
19.5
19.4
29
16
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.2
19.3
93
349
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.2
19.2
94
356
WW500
NOMESCO Finland
Blood transfusion
5.3
19.0
40
82
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
4.2
18.8
54
143
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
6.7
18.8
31
50
C10AA01
ATC
simvastatin; oral
2.7
18.6
240
1490
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.8
18.6
45
104
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
46.5
18.4
22
5
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
4.7
18.1
45
106
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.9
18.1
60
176
S97
ICPC
Chronic ulcer skin
4.0
18.0
56
157
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
99.8
17.7
19
*
R06.0
ICD-10 Finland
Dyspnoea
2.6
17.7
148
742
207
Kela drug reimbursment
Chronic arrhythmias
2.9
17.6
107
455
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
4.9
17.5
41
92
J01MA14
ATC
moxifloxacin; systemic
3.6
17.4
64
202
A10AB01
ATC
insulin (human); parenteral
5.9
17.3
32
58
WX892
NOMESCO Finland
Monitored bed care
3.7
17.2
60
182
L28
ICPC
Limited function/disability (L)
2.8
17.2
110
480
Z2446
NOMESCO Finland
Social worker
4.4
17.2
46
115
A02BC02
ATC
pantoprazole; systemic
2.9
16.9
296
2091
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.1
16.9
51
140
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
5.5
16.8
34
67
A12AA12
ATC
[U] calcium acetate
94.3
16.7
18
*
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
94.3
16.7
18
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.5
16.5
206
1236
B99
ICD-10 Finland
Other and unspecified infectious diseases
7.2
16.3
25
37
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
31.6
16.3
21
7
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
5.7
16.2
31
58
ZXE10
NOMESCO Finland
More than one and less than three hours
2.5
16.2
174
973
L17
ICPC
Foot/toe symptom/complaint
2.6
16.0
136
682
E66.00
ICD-10 Finland
Metabolic syndrome
4.6
15.9
40
95
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.5
15.8
154
822
H05BX02
ATC
paricalcitol; systemic
+∞
15.7
15
*
TPH07
NOMESCO Finland
Cathetrisation of artery
3.1
15.6
75
278
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
15.6
132
658
T90
ICPC
Diabetes non-insulin dependent
2.5
15.6
137
696
A10BB12
ATC
glimepiride; oral
3.5
15.5
60
195
WX882
NOMESCO Finland
High dependency care
6.2
15.5
27
46
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
5.6
15.4
30
57
N02AX02
ATC
tramadol; systemic, rectal
2.4
15.3
208
1280
B01AC04
ATC
clopidogrel; oral
2.6
15.3
117
555
A10AE05
ATC
insulin detemir; parenteral
4.4
15.3
40
98
C01DA14
ATC
isosorbide mononitrate; oral
2.6
15.3
111
514
E86
ICD-10 Finland
Volume depletion
6.3
15.0
26
44
PB1DE
NOMESCO Finland
Upper extremity arteries ultrasound examination with Doppler method
59.1
14.9
17
*
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
26.3
14.8
20
8
C03DA01
ATC
spironolactone; oral
2.9
14.8
81
323
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.4
14.7
57
185
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
+∞
14.7
14
*
N18
ICD-10 Finland
Chronic kidney disease
16.2
14.6
23
15
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
5.9
14.5
27
49
ZXA05
NOMESCO Finland
Left side
2.4
14.4
133
687
R11
ICD-10 Finland
Nausea and vomiting
3.6
14.3
51
157
Z3226
NOMESCO Finland
Physiotherapist
2.7
14.2
98
440
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
5.0
14.0
31
66
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
12.1
14.0
25
22
3025
Kela drug reimbursment
Calcium carbonate
31.4
14.0
18
6
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
4.1
14.0
40
105
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.8
14.0
82
339
AN1
HP
Coronary angiography
2.8
13.7
83
348
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
5.5
13.6
27
52
Z94.9
ICD-10 Finland
Transplanted organ and tissue status, unspecified
+∞
13.6
13
*
K65.0
ICD-10 Finland
Acute peritonitis
17.0
13.6
21
13
ZXA00
NOMESCO Finland
Right side
2.3
13.6
142
771
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
26.9
13.5
18
7
A10AB04
ATC
insulin lispro; parenteral
6.0
13.4
24
42
C07AB02
ATC
metoprolol; systemic
2.4
13.3
116
581
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
41.7
13.3
16
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
4.3
13.2
36
91
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.3
13.2
141
771
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
5.5
13.2
26
50
A07AA09
ATC
vancomycin; oral
17.5
13.1
20
12
A10AA02, ,
ATC
5.3
13.1
27
54
RD210, ,
NOMESCO Finland
13.7
13.1
22
17
N18.3
ICD-10 Finland
Chronic kidney disease, stage 3
11.1
12.9
24
23
AA1AD
NOMESCO Finland
CT of head and brain
2.3
12.7
142
790
N04.1
ICD-10 Finland
Nephrotic syndrome, focal and segmental glomerular lesions
72.3
12.7
14
*
A10AA01, ,
ATC
6.5
12.6
21
34
E66.8
ICD-10 Finland
Other obesity
5.1
12.6
27
56
KBV00
NOMESCO Finland
Insertion of stent into ureter
25.3
12.6
17
7
D638, N189,
ICD-10 Finland
+∞
12.6
12
*
N03.0
ICD-10 Finland
Chronic nephritic syndrome, minor glomerular abnormality
+∞
12.6
12
*
PBU84
NOMESCO Finland
Plastic repair of arteriovenous fistula from artery of upper extremity
134.3
12.5
13
*
D89.80
ICD-10 Finland
Immunoglobulin A (IgA) deposits in organisms
134.3
12.5
13
*
B01AF02
ATC
apixaban; oral
2.7
12.5
80
345
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.0
12.4
62
234
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
5.4
12.4
25
49
Z2221
NOMESCO Finland
Medical doctor
2.3
12.3
124
659
RS220, ,
NOMESCO Finland
22.2
12.1
17
8
E0000UV, ,
ATC
2.2
12.0
167
1010
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
48.3
12.0
14
*
H02AB07
ATC
prednisone; oral
2.7
11.9
71
294
R60.9
ICD-10 Finland
Oedema, unspecified
4.0
11.9
35
94
Q61.3
ICD-10 Finland
Polycystic kidney, unspecified
31.1
11.7
15
5
N08.2
ICD-10 Finland
Glomerular disorders in blood diseases and disorders involving the immune mechanism
67.1
11.7
13
*
A10BH01
ATC
sitagliptin; oral
2.9
11.6
62
242
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.5
11.6
84
383
PG5AC
NOMESCO Finland
Contrast examination of injection gate to artery or vein
+∞
11.5
11
*
M01AB01
ATC
indometacin; systemic, rectal
3.1
11.3
51
181
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.4
11.3
101
507
ZXE20
NOMESCO Finland
More than three and less than five hours
2.5
11.3
80
361
K07
ICPC
Swollen ankles/oedema
3.8
11.2
36
103
C08DB01
ATC
diltiazem; oral
3.6
11.2
39
118
I42.0
ICD-10 Finland
Dilated cardiomyopathy
4.7
11.1
26
58
NHQ40
NOMESCO Finland
Amputation of toe
6.0
11.1
20
35
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
5.1
11.1
24
50
M79.6
ICD-10 Finland
Pain in limb
2.1
11.1
166
1025
A28
ICPC
Limited function/disability NOS
2.3
11.0
103
527
H43.1
ICD-10 Finland
Vitreous haemorrhage
5.1
10.9
23
47
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.1
10.9
149
888
R02
ICPC
Shortness of breath/dyspnoea
2.7
10.8
65
270
J01MA12
ATC
levofloxacin; systemic
2.3
10.8
105
545
SPAT1255
SPAT
Intravenous administration of medicine
3.4
10.8
41
131
R80
ICD-10 Finland
Isolated proteinuria
22.2
10.8
15
7
WX202
NOMESCO Finland
Supraclavicular plexus blockade
11.7
10.7
19
17
C09BA02
ATC
enalapril and diuretics; systemic
2.9
10.6
52
194
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
10.5
165
1030
N03.3
ICD-10 Finland
Chronic nephritic syndrome, diffuse mesangial proliferative glomerulonephritis
113.0
10.5
11
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.8
10.5
33
93
A10BH02
ATC
vildagliptin; oral
5.4
10.4
21
41
WZC30
NOMESCO Finland
Teaching
2.4
10.4
80
374
E66.01
ICD-10 Finland
Obesity due to excess calories
3.5
10.3
36
109
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
5.0
10.1
22
46
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
5.0
10.1
22
46
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
3.5
10.0
36
111
A08
ICPC
Swelling
3.5
10.0
35
106
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
4.6
9.9
24
55
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.0
9.9
160
1004
N02BE01
ATC
paracetamol; systemic, rectal
3.2
9.9
347
2925
B01AB05
ATC
enoxaparin; parenteral
2.0
9.9
146
888
H3603, E103,
ICD-10 Finland
26.8
9.9
13
5
SAA03
NOMESCO Finland
Extended examination of mouth
2.0
9.8
145
881
GD1AD
NOMESCO Finland
Thorax CT examination
3.3
9.8
39
128
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.0
9.8
169
1086
C09CA06
ATC
candesartan; oral
2.2
9.8
106
573
ZXE40
NOMESCO Finland
More than seven and less than nine hours
5.5
9.7
19
36
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
4.5
9.7
24
56
SPAT1254
SPAT
Administration of medicine
2.4
9.7
74
344
306
Kela drug reimbursment
Erythropoietin and darbepoetin
56.5
9.7
11
*
E21.1
ICD-10 Finland
Secondary hyperparathyroidism, not elsewhere classified
56.5
9.7
11
*
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
5.2
9.7
20
40
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
9.6
89
450
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.5
9.6
34
104
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.6
9.6
59
248
A41.8
ICD-10 Finland
Other specified sepsis
5.4
9.5
19
37
58209
ICD-8 Finland
Chronic nephritis, Unspecified
102.5
9.5
10
*
N11.9
ICD-10 Finland
Chronic tubulo-interstitial nephritis, unspecified
102.5
9.5
10
*
L04AA05
ATC
[U] tacrolimus
102.5
9.5
10
*
Z99.2
ICD-10 Finland
Dependence on renal dialysis
102.5
9.5
10
*
L30.3
ICD-10 Finland
Infective dermatitis
4.7
9.4
22
49
N11.8
ICD-10 Finland
Other chronic tubulo-interstitial nephritis
+∞
9.4
9
*
V03AE04
ATC
calcium acetate and magnesium carbonate; systemic
+∞
9.4
9
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.7
9.4
31
90
C02EA02, ,
ATC
3.5
9.4
33
100
XCK10
NOMESCO Finland
Photography of fundus of eye
2.6
9.4
58
244
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.2
9.3
95
500
S18
ICPC
Laceration/cut
2.0
9.3
197
1351
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.5
9.3
64
284
I25.2
ICD-10 Finland
Old myocardial infarction
2.7
9.2
51
203
I50
ICD-10 Finland
Heart failure
4.0
9.1
26
68
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.8
9.1
49
192
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.1
8.9
38
130
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
4.0
8.9
26
69
C03AA03
ATC
hydrochlorothiazide; oral
2.7
8.9
50
200
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
2.0
8.8
122
721
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.8
8.7
45
172
WX722
NOMESCO Finland
PEEP
3.2
8.7
36
121
K65.9
ICD-10 Finland
Peritonitis, unspecified
51.2
8.7
10
*
N02AA05
ATC
oxycodone; systemic
2.1
8.7
96
520
B07.9
ICD-10 Finland
Verruca simplex
4.7
8.7
20
44
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.9
8.7
43
161
WX002
NOMESCO Finland
Sedation and analgesia
2.1
8.5
93
501
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.2
8.5
85
443
WX204
NOMESCO Finland
Axillary plexus blockaced
4.2
8.5
23
58
K78
ICPC
Atrial fibrillation/flutter
2.6
8.4
50
206
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
3.6
8.4
28
82
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.2
8.4
81
416
KAS40
NOMESCO Finland
Excision of transplanted kidney
+∞
8.4
8
*
N17.8
ICD-10 Finland
Other acute renal failure
9.8
8.4
16
17
C09DA01
ATC
losartan and diuretics; oral
2.5
8.3
55
239
PG1XE
NOMESCO Finland
Other ultrasound examination of blood vessel not elsewhere classified
14.9
8.3
13
9
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.2
8.2
33
109
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.9
8.2
41
154
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.4
8.2
64
300
R53
ICD-10 Finland
Malaise and fatigue
2.0
8.2
107
616
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.5
8.1
57
254
C10AX09
ATC
ezetimibe; oral
2.2
8.1
83
435
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.6
8.0
48
198
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
3.3
8.0
31
100
R31
ICD-10 Finland
Unspecified haematuria
2.3
8.0
69
337
UJF32
NOMESCO Finland
Coloscopy
2.0
8.0
121
732
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.9
8.0
136
856
201
Kela drug reimbursment
Chronic cardiac insufficiency
3.0
7.9
36
128
A10BK01
ATC
dapagliflozin; oral
2.8
7.9
40
151
M25.5
ICD-10 Finland
Pain in joint
2.0
7.9
115
686
C08CA05
ATC
nifedipine; systemic
3.0
7.9
37
134
Z3229
NOMESCO Finland
Other healthcare associate professional
2.6
7.9
48
200
XF404
NOMESCO Finland
Ambulatory ECG
2.5
7.9
51
219
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
2.7
7.8
44
176
N02AJ06
ATC
codeine and paracetamol; systemic
1.9
7.8
163
1094
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
15.4
7.8
12
8
WX610
NOMESCO Finland
Patient controlled analgesia
15.4
7.8
12
8
7151
FHL
Kidney transplantation
45.9
7.7
9
*
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
45.9
7.7
9
*
N03.8
ICD-10 Finland
Chronic nephritic syndrome, other
45.9
7.7
9
*
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
3.0
7.7
36
130
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
4.1
7.7
21
53
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
3.8
7.7
24
67
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.6
7.7
47
196
ZXE00
NOMESCO Finland
One hour or less
1.9
7.7
154
1020
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.2
7.7
75
386
I20.09
ICD-10 Finland
Unstable angina
2.7
7.6
42
166
PD4AC
NOMESCO Finland
Arterigography of lower extremity with X-ray
6.4
7.6
19
31
D63.8
ICD-10 Finland
Anaemia in other chronic diseases classified elsewhere
25.6
7.6
10
*
TPH05
NOMESCO Finland
Open cannulation of peripheral vein
10.3
7.6
14
14
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.2
7.5
31
104
SPAT1211
SPAT
Application of soft bandage
2.7
7.5
43
174
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.7
7.5
40
156
PB1BC
NOMESCO Finland
Extensive angiography of upper extremity with X-ray
81.6
7.4
8
*
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
3.0
7.4
33
116
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
1.9
7.4
111
667
PE1YT
NOMESCO Finland
Femoral or popliteal artery PTA with stent
8.6
7.4
15
18
AN4
HP
Balloon angioplasty and drug eluding stent
3.5
7.4
26
79
SPAT1099
SPAT
Measurement of blood pressure with Doppler ultrasound device
3.5
7.4
25
74
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.7
7.4
40
157
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
4.3
7.4
19
46
C09AA05
ATC
ramipril; oral
1.9
7.4
133
850
XF602
NOMESCO Finland
Bloodpressure monitoring
9.6
7.3
14
15
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
6.5
7.3
18
29
58200
ICD-8 Finland
Chronic nephritis, Cum uraemia
+∞
7.3
7
*
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.9
7.3
119
735
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
2.2
7.3
65
322
KBV10
NOMESCO Finland
Removal of stent from ureter
16.1
7.3
11
7
A10BB01
ATC
glibenclamide; oral
3.1
7.3
30
101
I21.41
ICD-10 Finland
Acute subendocardial infarction stenosed coronary artery
2.9
7.2
35
129
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
3.6
7.2
24
70
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.2
7.2
64
316
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.7
7.2
39
153
B01AB04
ATC
dalteparin; parenteral
3.2
7.2
28
91
FM1LE
NOMESCO Finland
Combined ultrasound and EKG examination of heart with tolerance test
20.5
7.2
10
5
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
3.0
7.1
31
108
H25.1
ICD-10 Finland
Senile nuclear cataract
1.8
7.1
140
919
WZC00
NOMESCO Finland
Treatment plan or consultation
1.8
7.0
135
878
K05.30
ICD-10 Finland
Periodontitis complex
2.2
7.0
64
320
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
7.8
7.0
15
20
R5140
NOMESCO Finland
Monitoring the use of the aid
2.3
7.0
58
279
R04.0
ICD-10 Finland
Epistaxis
2.6
6.9
43
181
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.3
6.9
53
246
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.9
6.9
20
53
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
6.9
6.9
16
24
N03AX16
ATC
[U] pregabalin
2.0
6.9
95
554
C07FB02
ATC
metoprolol and felodipine; systemic
3.8
6.8
21
58
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
6.8
65
330
C10AA04
ATC
fluvastatin; oral
2.3
6.8
53
247
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.4
6.8
47
208
SPAT1263
SPAT
Sampling
1.8
6.8
159
1094
ZST00
NOMESCO Finland
Procedure related to previous procedure classified in chapter T
40.8
6.8
8
*
N03.1
ICD-10 Finland
Chronic nephritic syndrome, focal and segmental glomerular lesions
40.8
6.8
8
*
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.9
6.8
101
604
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
6.6
6.7
16
25
S76
ICPC
Skin infection other
3.1
6.7
28
95
SPAT1229
SPAT
Assessment of need for aid
2.6
6.7
39
159
XG466
NOMESCO Finland
Sleep oxymetry
3.5
6.7
23
69
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.1
6.6
69
363
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
8.9
6.6
13
15
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.4
6.6
49
224
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.9
6.6
31
113
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
5.5
6.5
18
34
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
5.9
6.5
17
30
UJF30
NOMESCO Finland
Ileoscopy through colon
2.4
6.5
47
212
C08CA03
ATC
isradipine; systemic
7.6
6.5
14
19
187
Kela drug reimbursment
MPA
71.0
6.4
7
*
T86.1
ICD-10 Finland
Kidney transplant failure and rejection
71.0
6.4
7
*
TK830
NOMESCO Finland
Ultrafiltration
71.0
6.4
7
*
Z94.1
ICD-10 Finland
Heart transplant status
71.0
6.4
7
*
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.9
6.4
19
51
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
14.6
6.4
10
7
ZY010
NOMESCO Finland
Hospital outpatient
3.7
6.4
20
56
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.6
6.4
21
61
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
2.5
6.4
40
169
JAF30
NOMESCO Finland
Repair of umbilical hernia using prosthetic material
6.1
6.4
16
27
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
7.2
6.3
14
20
I12
ICD-10 Finland
Hypertensive renal disease
+∞
6.3
6
*
N03.5
ICD-10 Finland
Chronic nephritic syndrome, diffuse mesangiocapillary glomerulonephritis
+∞
6.3
6
*
5850B
ICD-9 Finland
Chronic renal failure[INSUFFICIENTIA RENIS CHRONICA CUM URAEMIA]
+∞
6.3
6
*
5829A
ICD-9 Finland
Chronic glomerulonephritis with unspecified pathological lesion in kidney[GLOMERULONEPHRITIS CHRONICA NUD ,EI NEFR SDR]
+∞
6.3
6
*
Q61.0
ICD-10 Finland
Congenital single renal cyst
+∞
6.3
6
*
BBA50
NOMESCO Finland
Total parathyroidectomy
+∞
6.3
6
*
N05.9
ICD-10 Finland
Unspecified nephritic syndrome, unspecified
27.2
6.3
8
*
K92.1
ICD-10 Finland
Melaena
2.8
6.2
32
122
J01DA01
ATC
[U] cefalexin
1.7
6.2
229
1776
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.6
6.2
37
153
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.2
6.2
24
78
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.7
6.1
166
1181
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.7
6.1
19
53
AN3
HP
Balloon angioplasty and metallic stent
3.4
6.1
22
68
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.3
6.1
49
232
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.3
6.1
49
232
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
5.3
6.1
17
33
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
10.3
6.1
11
11
PF1BT
NOMESCO Finland
Extensive PTA of arteries of knee, lower leg and ankle
10.3
6.1
11
11
C09CA03
ATC
valsartan; oral
2.3
6.1
47
219
XF600
NOMESCO Finland
Bloodpressure measurement
2.6
6.1
35
142
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
4.0
6.1
17
44
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
275
282
32.89
274.51
26.2
7.1
16.91
10.57
mmol/l
22.69
264
266
241
236
26.30
243.35
13.1
3.7
189.22
83.67
ng/l
16.74
223
207
285
429
23.75
215.71
26.7
5.5
1.21
1.01
mmol/l
16.19
274
395
321
819
20.08
150.71
8.9
2.6
3297.05
8161.47
umol/l
0.99
311
710
242
458
12.85
144.21
9.8
2.4
22.31
22.91
%
0.28
225
393
196
306
12.19
135.14
14.5
3.9
0.90
1.84
mmol/l
2.30
174
245
85
57
18.93
99.61
9.1
7.1
353.24
106.00
iu/ml
—
25
8
126
169
10.67
94.75
2.1
1.9
1.67
1.50
g/l
1.00
117
148
202
516
7.24
83.43
5.7
3.4
0.81
0.82
mmol/l
0.47
195
479
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
100
117
11.25
82.67
4.1
2.1
0.33
0.37
u/ml
0.20
55
59
81
76
13.28
77.65
1.7
1.5
—
—
—
0
0
283
1048
7.71
77.01
9.9
3.7
40.72
9.26
mg/mmol
8.02
258
680
62
43
17.04
70.64
2.6
1.5
110.05
93.29
u/ml
—
18
7
164
401
6.45
68.99
3.7
4.1
247.80
242.15
u/l
0.27
156
379
293
1207
7.29
68.05
10.7
3.4
—
—
—
0
0
264
1002
6.39
66.99
8.0
3.1
6.12
7.80
mmol/l
12.25
251
822
315
1416
8.25
65.43
18.5
4.9
33.81
34.91
g/l
3.38
306
1324
280
1154
6.46
63.45
4.8
2.2
75.29
77.49
nmol/l
0.64
270
1008
282
1170
6.51
63.39
9.8
2.6
272.78
168.30
ug/l
7.08
275
1066
261
1018
6.02
62.97
9.6
3.5
34.71
123.42
e6/l
0.78
244
789
60
51
13.79
60.69
1.6
1.1
318.96
313.38
u/ml
0.02
49
24
60
53
13.26
59.23
1.6
1.2
—
—
—
0
0
115
232
6.68
58.15
8.9
3.2
1.34
1.70
mmol/l
0.38
76
173
203
683
5.25
57.32
6.9
2.8
3.95
3.88
e6/l
0.03
197
616
240
924
5.36
57.27
8.7
3.4
0.28
0.54
e6/l
1.59
221
701
68
77
10.54
56.69
1.8
1.6
13678.33
10787.17
e6/l
0.43
52
58
321
1590
7.66
55.99
39.8
6.7
1.21
1.21
mmol/l
0.35
289
1346
266
1139
5.48
54.84
11.0
4.0
44.60
138.69
e6/l
0.90
245
836
122
279
5.97
53.73
3.0
2.9
63.68
65.99
g/l
2.07
113
254
147
425
5.02
48.81
4.1
2.6
2.13
1.84
%
2.18
136
385
169
562
4.62
46.65
6.7
3.1
1.66
1.21
e6/l
0.54
118
325
285
1462
4.83
42.13
29.8
6.0
1.22
1.21
mmol/l
1.58
274
1323
166
583
4.29
41.81
5.8
2.9
0.77
0.95
e6/l
0.36
116
344
69
120
6.81
39.57
2.4
4.2
47.86
42.03
mg/l
0.33
54
99
97
233
5.25
39.46
2.5
1.6
—
—
—
0
0
161
578
4.10
38.85
2.9
1.9
—
—
—
0
0
68
120
6.69
38.41
2.4
4.1
77.07
116.17
mg/l
0.33
52
97
94
231
5.08
37.07
6.6
2.7
25.64
64.98
ml/min/173m2
30.94
64
105
191
821
3.67
34.46
3.6
2.0
3.36
3.10
mg/l
0.75
177
714
50
71
7.96
34.34
3.7
2.3
124.74
127.63
g/l
0.28
43
52
262
1398
3.83
33.35
12.1
5.7
3.08
2.89
%
0.53
255
1313
290
1664
4.16
32.85
43.3
16.0
1.38
1.34
inr
0.30
85
441
260
1408
3.70
31.73
11.5
5.7
63.20
58.34
%
9.76
254
1326
263
1436
3.72
31.65
12.1
5.9
20.92
26.06
%
13.64
257
1349
109
343
4.06
30.79
5.4
3.6
—
—
—
0
0
312
1926
4.51
30.76
13.1
4.9
7.76
6.86
mmol/l
5.81
304
1821
120
409
3.83
30.17
2.6
1.9
—
—
—
0
0
219
1090
3.39
30.13
5.6
3.1
7179.61
1625.12
ng/l
9.30
209
941
289
1724
3.85
29.25
13.8
9.2
4.93
4.28
e9/l
5.14
265
1509
119
412
3.75
29.12
2.6
1.9
—
—
—
0
0
31
29
11.55
29.03
1.5
1.3
11817.00
143362.00
e6/l
0.63
19
19
248
1357
3.39
28.62
2.9
2.0
94.00
92.63
pmol/l
0.16
143
725
158
670
3.33
27.92
2.4
1.7
1169.35
1186.54
nmol/l
0.06
141
506
44
70
6.98
27.16
4.4
2.4
15.77
15.52
%
0.14
39
36
36
47
8.36
26.38
1.4
1.2
—
—
—
0
0
204
1031
3.12
26.29
6.4
3.4
2.34
2.34
mmol/l
0.07
191
897
114
414
3.51
25.57
7.2
7.4
5.00
5.09
kpa
0.37
107
393
114
415
3.50
25.46
7.2
7.4
10.44
11.47
kpa
1.72
105
396
113
410
3.50
25.36
7.3
7.5
-0.13
0.99
mmol/l
1.47
92
335
60
140
4.90
24.68
2.4
2.1
—
—
—
0
0
29
6
52.10
24.65
15.8
7.0
5.52
7.62
mmol/l
—
29
6
49
99
5.54
23.72
2.0
1.2
—
—
—
0
0
29
33
9.43
23.60
1.1
1.1
—
—
—
0
0
306
2034
3.62
23.13
8.9
4.6
1130.00
2015.25
e6/l
—
5
40
161
761
2.94
22.62
4.4
2.6
—
—
—
0
0
36
56
7.00
22.61
8.6
2.0
72.89
65.48
%
0.94
36
56
244
1457
2.89
21.70
9.1
3.8
0.00
0.00
estimate
0.50
61
292
240
1421
2.88
21.69
4.6
2.7
—
—
—
0
0
29
37
8.40
21.57
1.4
1.5
70.71
63.46
%
0.43
23
28
244
1466
2.87
21.28
9.1
3.9
0.00
0.00
estimate
-0.00
56
254
44
89
5.46
21.22
2.3
1.5
—
—
—
0
0
333
2393
4.23
21.05
21.2
7.8
91.43
79.27
u/l
2.27
323
2243
32
19
18.27
20.87
1.2
1.2
—
—
—
0
0
240
1445
2.80
20.58
12.8
5.3
0.00
0.00
estimate
-0.00
58
266
99
383
3.15
19.50
1.3
1.3
9.64
10.47
u/ml
0.03
29
149
43
92
5.14
19.44
3.5
2.2
284.11
84.54
ug/min
0.83
30
50
30
46
7.00
19.03
1.5
1.3
23.38
27.77
g/l
0.85
25
41
38
75
5.52
18.78
2.3
1.8
—
—
—
0
0
51
132
4.31
18.27
2.3
2.3
288.19
664.14
ug/l
0.59
51
126
41
89
5.04
18.21
1.5
1.6
—
—
—
0
0
67
212
3.62
18.13
2.0
1.5
—
—
—
0
0
31
52
6.40
18.07
2.3
1.9
—
—
—
0
0
161
839
2.60
17.79
2.1
1.6
20.13
20.34
nmol/l
0.05
153
712
29
21
14.85
17.59
1.1
1.1
—
—
—
0
0
179
986
2.55
17.54
2.3
2.1
142.31
319.63
u/l
1.45
174
928
36
76
5.13
16.48
2.3
1.8
—
—
—
0
0
21
7
31.63
16.28
1.0
1.0
—
—
—
0
0
211
1323
2.34
14.68
6.9
4.1
128.10
51.63
ng/l
1.17
187
1023
23
35
6.93
14.64
1.7
1.9
—
—
—
0
0
127
639
2.49
14.59
2.8
1.7
1.42
1.42
mg/l
0.00
107
497
94
412
2.70
14.33
1.4
1.2
30.99
34.64
iu/ml
0.15
32
133
79
318
2.88
14.15
3.7
2.9
7.50
7.60
ug/l
0.01
74
281
33
74
4.79
14.06
2.4
1.4
—
—
—
0
0
297
2195
2.63
13.82
7.6
4.1
30.13
13.09
mm/h
21.76
284
1996
127
654
2.42
13.74
7.7
3.9
70.09
360.81
ng/l
2.52
118
549
62
222
3.14
13.63
2.3
1.7
—
—
—
0
0
32
72
4.76
13.58
1.6
1.5
—
—
—
0
0
26
49
5.62
13.44
2.3
1.8
—
—
—
0
0
26
49
5.62
13.44
2.3
1.8
—
—
—
0
0
25
46
5.75
13.24
1.9
1.7
—
—
—
0
0
29
63
4.90
12.82
1.6
1.7
—
—
—
0
0
24
26
9.78
12.17
1.3
1.3
19.04
29.04
%
0.67
19
18
163
981
2.16
11.79
4.3
3.4
48.46
33.82
u/l
0.58
157
935
42
130
3.51
11.61
3.0
2.1
41.75
40.19
u/l
0.21
36
115
25
52
5.08
11.60
1.4
1.7
—
—
—
0
0
340
2803
3.07
10.76
14.0
6.3
44.54
40.85
mmol/mol
5.90
332
2585
29
75
4.10
10.32
1.6
1.4
—
—
—
0
0
29
75
4.10
10.32
1.6
1.4
—
—
—
0
0
30
80
3.99
10.25
2.8
2.1
—
—
—
0
0
24
54
4.68
10.17
1.7
1.7
—
—
—
0
0
22
46
5.02
10.14
1.6
1.8
—
—
—
0
0
39
127
3.31
9.95
2.8
3.2
—
—
—
0
0
348
2947
3.21
9.66
63.0
16.3
29.09
27.09
mg/l
0.57
338
2409
66
294
2.51
9.49
4.6
2.4
44.30
35.76
u/l
0.87
61
247
55
225
2.69
9.39
10.3
6.4
23.92
24.33
mmol/l
0.32
49
213
111
622
2.11
9.27
3.5
3.3
2.51
2.45
mmol/l
3.60
96
542
269
2058
2.06
9.19
4.2
3.6
14.78
15.03
pmol/l
0.88
255
1829
25
65
4.05
8.84
1.6
1.4
—
—
—
0
0
25
65
4.05
8.84
2.2
1.4
—
—
—
0
0
332
2780
2.57
8.75
7.5
4.2
1.70
1.28
mmol/l
11.92
316
2517
18
38
4.92
8.20
1.3
1.2
2.89
1.92
u/ml
—
9
13
166
1128
1.84
7.60
10.4
4.1
—
—
—
0
0
335
2872
2.43
7.40
7.9
4.7
1.22
1.39
mmol/l
12.13
320
2615
336
2898
2.41
7.08
8.0
4.8
4.04
4.42
mmol/l
9.21
322
2656
62
307
2.22
6.94
3.0
2.5
0.23
0.20
g/l
1.82
56
285
14
17
8.50
6.88
1.2
1.2
19.93
41.82
u/l
0.88
14
17
14
17
8.50
6.88
1.2
1.2
73.79
108.71
u/l
0.59
14
17
26
83
3.29
6.85
1.4
1.4
—
—
—
0
0
18
33
5.67
6.69
4.3
2.1
—
—
—
0
0
113
706
1.86
6.60
1.8
1.8
477.91
6969073.19
pmol/l
0.50
103
574
36
142
2.70
6.58
4.0
1.7
—
—
—
0
0
340
2971
2.40
6.54
8.4
5.3
2.17
2.58
mmol/l
16.89
326
2703
9
5
18.39
6.29
1.0
1.0
1652.56
1392.00
miu/ml
—
9
5
6
0
+∞
6.26
4.2
0.0
—
—
—
0
0
18
36
5.20
6.26
1.9
1.7
—
—
—
0
0
18
36
5.20
6.26
1.9
1.7
—
—
—
0
0
33
129
2.71
6.14
3.3
1.6
—
—
—
0
0
308
2614
1.95
6.08
5.7
4.4
2.36
1.97
mu/l
3.69
291
2350
15
26
5.96
5.90
1.5
1.5
—
—
—
0
0
121
798
1.76
5.81
10.0
4.0
0.00
0.00
estimate
0.50
48
255
199
1503
1.68
5.79
3.4
2.3
—
—
—
0
0
18
52
3.58
5.52
1.1
1.1
—
—
—
0
0
16
33
5.01
5.49
2.0
1.8
—
—
—
0
0
14
26
5.55
5.27
1.9
1.9
—
—
—
0
0
16
44
3.75
5.26
2.2
1.9
32.69
32.91
pg
0.11
16
44
23
81
2.96
5.18
1.8
1.5
266.12
273.21
ug/g
0.07
17
50
15
40
3.86
5.14
2.5
1.5
—
—
—
0
0
15
41
3.77
4.97
2.5
1.4
—
—
—
0
0
15
41
3.77
4.97
2.5
1.4
—
—
—
0
0
15
41
3.77
4.97
2.5
1.4
—
—
—
0
0
15
41
3.77
4.97
2.4
1.4
—
—
—
0
0
17
51
3.44
4.94
4.8
2.2
3.70
4.54
e9/l
0.85
17
51
14
29
4.97
4.86
2.9
1.9
—
—
—
0
0
14
29
4.97
4.86
2.9
1.9
—
—
—
0
0
14
29
4.97
4.86
2.9
1.9
—
—
—
0
0
15
42
3.68
4.81
1.5
1.2
1.86
7.91
u/ml
—
7
22
15
42
3.68
4.81
2.5
1.4
—
—
—
0
0
22
79
2.89
4.80
1.5
1.2
—
—
—
0
0
22
80
2.86
4.70
1.5
1.2
—
—
—
0
0
17
54
3.25
4.54
6.1
2.9
56.18
57.54
%
0.18
17
54
347
3151
2.20
4.53
71.5
19.5
220.04
84.16
umol/l
45.04
347
3151
11
19
5.93
4.47
1.1
1.2
170.82
181.03
mmol/24h
0.09
11
19
319
2820
1.83
4.46
56.9
15.1
34.91
76.27
ml/min/173m2
112.96
300
2358
7
6
11.85
4.29
1.0
1.2
106.29
106.67
%
—
7
6
228
1863
1.56
4.25
5.7
3.3
85.56
54.92
u/l
1.86
219
1725
9
13
7.06
4.18
4.4
1.9
92.67
99.23
%
—
9
13
26
111
2.44
4.09
1.5
1.3
—
—
—
0
0
13
32
4.17
3.94
2.5
1.9
—
—
—
0
0
11
23
4.89
3.90
2.3
1.3
—
—
—
0
0
11
23
4.89
3.90
2.3
1.3
—
—
—
0
0
6
5
12.16
3.77
3.7
1.4
197.33
61.40
ng/l
—
6
5
13
34
3.92
3.73
1.2
1.1
—
—
—
0
0
9
16
5.73
3.68
1.2
1.1
—
—
—
0
0
9
16
5.73
3.68
1.2
1.1
—
—
—
0
0
12
30
4.10
3.62
1.8
2.4
—
—
—
0
0
9
17
5.39
3.53
1.3
1.1
—
—
—
0
0
13
36
3.70
3.53
2.5
1.8
—
—
—
0
0
8
13
6.26
3.52
2.9
2.0
—
—
—
0
0
8
13
6.26
3.52
3.0
2.0
—
—
—
0
0
6
6
10.13
3.51
1.0
1.2
—
—
—
0
0
350
3240
2.05
3.50
84.0
24.0
36.33
40.05
%
20.43
331
2996
10
22
4.64
3.45
1.6
1.9
—
—
—
0
0
16
59
2.79
3.36
1.1
1.2
—
—
—
0
0
78
529
1.60
3.19
1.3
1.2
1.22
1.12
u/ml
0.09
20
140
8
16
5.08
3.06
1.7
2.1
—
—
—
0
0
11
31
3.62
3.01
1.1
1.2
—
—
—
0
0
9
22
4.16
2.90
2.6
1.3
—
—
—
0
0
9
22
4.16
2.90
2.6
1.3
—
—
—
0
0
9
23
3.98
2.79
1.0
1.3
—
—
—
0
0
6
10
6.08
2.70
1.2
1.4
—
—
—
0
0
12
42
2.92
2.57
1.0
1.0
—
—
—
0
0
7
16
4.44
2.48
1.9
2.1
—
—
—
0
0
6
12
5.06
2.41
3.0
2.0
—
—
—
0
0
6
12
5.06
2.41
3.0
2.0
—
—
—
0
0
5
8
6.31
2.38
2.0
1.1
1.15
1.28
mmol/l
—
5
8
7
17
4.17
2.37
2.9
1.5
1.00
0.99
g/l
—
7
17
6
13
4.67
2.28
3.2
1.9
—
—
—
0
0
12
49
2.50
2.12
1.2
1.1
—
—
—
0
0
27
157
1.77
1.98
1.1
1.3
—
58.78
—
0
16
12
51
2.40
1.97
1.2
1.3
—
46.24
—
0
5
311
2898
1.41
1.79
8.7
5.0
6.70
6.10
mmol/l
5.28
296
2621
6
18
3.37
1.75
1.5
1.8
—
—
—
0
0
8
178
0.44
1.74
1.1
1.8
—
—
—
0
0
6
19
3.19
1.66
6.3
4.2
—
—
—
0
0
10
42
2.42
1.63
1.0
1.1
1.67
1.49
g/l
—
10
36
5
14
3.60
1.62
1.0
1.2
6.02
7.77
mmol/l
—
5
14
5
14
3.60
1.62
1.0
1.3
—
—
—
0
0
7
26
2.72
1.58
1.1
1.2
—
—
—
0
0
7
26
2.72
1.58
1.1
1.2
—
—
—
0
0
7
26
2.72
1.58
1.1
1.2
—
—
—
0
0
7
26
2.72
1.58
1.1
1.2
—
—
—
0
0
7
26
2.72
1.58
1.1
1.2
—
—
—
0
0
10
44
2.31
1.56
4.0
3.8
—
—
—
0
0
5
15
3.36
1.53
4.2
1.7
1370.40
1108.80
u/ml
—
5
15
5
16
3.15
1.44
1.0
1.8
229.20
88.75
umol/l
—
5
16
5
16
3.15
1.44
1.6
1.1
—
—
—
0
0
28
182
1.58
1.42
2.3
2.5
—
15.49
—
0
10
98
802
1.30
1.40
1.9
1.7
1.86
1.34
mmol/l
5.13
92
674
49
360
1.41
1.39
2.4
4.5
3.73
49.34
ug/l
1.31
43
305
5
17
2.97
1.36
1.8
1.8
—
—
—
0
0
5
17
2.97
1.36
1.8
1.8
—
—
—
0
0
6
26
2.33
1.19
1.0
1.1
—
—
—
0
0
195
1761
1.22
1.14
4.3
5.2
2.37
2.68
ug/l
0.33
183
1569
41
308
1.37
1.06
1.2
1.3
—
—
—
0
0
10
53
1.91
1.02
1.2
1.3
—
—
—
0
0
19
124
1.56
0.98
1.1
1.2
18.55
104.27
iu/ml
—
6
39
7
36
1.96
0.97
1.0
1.3
—
—
—
0
0
11
62
1.80
0.95
1.2
1.1
—
16.78
—
0
5
0
24
0.00
0.79
0.0
1.0
—
—
—
0
0
9
54
1.68
0.75
1.3
1.3
10.78
2237.98
e6/l
—
9
43
9
54
1.68
0.75
1.0
1.2
0.56
8.86
e6/l
—
9
43
9
54
1.68
0.75
1.0
1.1
—
—
—
0
0
7
40
1.76
0.71
2.1
1.3
—
—
—
0
0
5
26
1.94
0.71
1.0
1.1
—
—
—
0
0
15
103
1.48
0.66
1.0
1.0
—
—
—
0
0
5
29
1.73
0.64
1.4
1.2
—
—
—
0
0
14
96
1.48
0.62
1.4
1.8
39.00
44.66
nmol/l
0.49
14
89
5
30
1.68
0.61
1.0
1.1
—
—
—
0
0
15
106
1.43
0.58
1.3
1.7
—
—
—
0
0
37
302
1.25
0.58
2.0
1.8
1.94
1.59
%
0.93
29
256
9
64
1.42
0.52
1.3
1.4
—
—
—
0
0
16
120
1.35
0.47
1.3
1.8
—
—
—
0
0
10
70
1.44
0.42
1.8
1.5
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
5
40
1.25
0.22
3.8
2.7
4.82
7.13
nmol/l
—
5
40
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
8.13
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.8
—
65.88
—
0
14
36
390
0.92
0.16
27.8
7.7
—
—
—
0
0
5
45
1.11
0.10
3.8
1.6
14.04
17.86
ug/l
—
5
45
102
1026
0.99
0.00
3.0
3.1
1.00
0.79
ug/l
0.89
81
703
18
179
1.01
0.00
1.4
1.4
—
—
—
0
0
143
1428
1.00
0.00
3.6
4.5
27.75
20.94
%
5.25
80
702
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint GOUT_KIDNEY and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| GOUT_KIDNEY | 3.249 [2.27, 4.66] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.047 |
During the follow-up period (1.1.1998 — 31.12.2019), 269 out of 519 females with GOUT_KIDNEY died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| GOUT_KIDNEY | 3.409 [2.41, 4.82] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 471 out of 1000 males with GOUT_KIDNEY died.
Mortality risk
Mortality risk for people of age
years, who have GOUT_KIDNEY.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.325% | 0.617% |
| 5 | 1.813% | 4.031% |
| 10 | 4.542% | 9.412% |
| 15 | 8.29% | 17.3% |
| 20 | 14.068% | 28.218% |
Relationships between endpoints
↥Index endpoint: GOUT_KIDNEY – Gout due to impairment of renal function
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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