gout: A condition characterized by painful swelling of the joints, which is caused by deposition of urate crystals.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
340 |
4. Check minimum number of eventsNone |
340 |
5. Include endpointsNone |
340 |
6. Filter based on genotype QC (FinnGen only) |
340 |
Control definitions (FinnGen only)
- Control exclude
- GOUT
Extra metadata
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M10
- Name in latin
- Arthritis urica ex insufficientia renali
Gout due to impairment of renal function
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1900 | 646 | 1244 |
| Only index persons | 1736 | 586 | 1150 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.02 | 0.03 |
| Only index persons | 0.04 | 0.02 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 73.96 | 77.27 | 72.23 |
| Only index persons | 73.66 | 76.82 | 72.05 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 340 | 90 | 250 |
| Unadjusted period prevalence (%) | 0.09 | 0.03 | 0.11 |
| Median age at first event (years) | 70.61 | 71.89 | 70.15 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 309
- Matched controls
- 3088
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M10.3
ICD-10 Finland
Gout due to impairment of renal function
+∞
323.0
309
*
M04AA01
ATC
allopurinol; systemic
86.6
210.6
272
241
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
42.0
148.4
196
122
M10.9
ICD-10 Finland
Gout, unspecified
65.9
145.4
167
54
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
90.2
137.2
148
31
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
85.5
124.9
136
28
A11CC03
ATC
alfacalcidol; systemic
78.8
115.1
127
27
N18.8
ICD-10 Finland
Other chronic renal failure
50.3
113.3
137
48
C03CA01
ATC
furosemide; systemic
13.7
88.3
251
741
A12AA04
ATC
calcium carbonate; oral
66.5
85.4
97
21
TK800
NOMESCO Finland
Hemodialysis
39.8
75.1
95
34
Z94.0
ICD-10 Finland
Kidney transplant status
141.8
64.8
67
6
212
Kela drug reimbursment
Gout
+∞
62.6
58
*
L04AA06
ATC
mycophenolic acid; systemic
69.1
61.9
70
13
B03XA02
ATC
darbepoetin alfa; parenteral
38.1
61.3
78
27
N18.0
ICD-10 Finland
End-stage renal disease
48.1
61.3
74
20
M10.0
ICD-10 Finland
Idiopathic gout
64.1
61.2
70
14
127
Kela drug reimbursment
Transplant complication
92.6
60.9
66
9
205
Kela drug reimbursment
Chronic hypertension
7.7
59.9
218
730
Z49.1
ICD-10 Finland
Extracorporeal dialysis
52.7
59.1
70
17
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
68.1
57.4
65
12
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
173.8
55.9
57
*
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
92.4
55.3
60
8
N19
ICD-10 Finland
Unspecified kidney failure
20.0
51.1
79
52
Z49.0
ICD-10 Finland
Preparatory care for dialysis
63.1
49.7
57
11
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
63.5
46.3
53
10
C08CA01
ATC
amlodipine; oral
5.8
44.8
216
885
137
Kela drug reimbursment
Uraemia requiring dialysis
74.1
44.7
50
8
I50.9
ICD-10 Finland
Heart failure, unspecified
6.7
43.4
133
311
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
235.2
40.9
41
*
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
228.6
39.8
40
*
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
152.4
38.7
40
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
10.4
38.4
80
100
V03AE01
ATC
polystyrene sulfonate; oral
45.0
35.4
43
11
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.7
34.5
166
612
N17.9
ICD-10 Finland
Acute renal failure, unspecified
12.9
34.4
63
60
288
Kela drug reimbursment
Febuxostat
+∞
34.0
32
*
L04AD01
ATC
ciclosporin; systemic
35.4
33.6
43
14
C02AC05
ATC
moxonidine; oral
9.9
32.9
70
89
B05DA
ATC
Isotonic solutions
80.9
32.6
36
5
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
10.1
32.5
68
84
M04AA03
ATC
febuxostat; oral
+∞
31.8
30
*
A46
ICD-10 Finland
Erysipelas
5.5
31.4
108
273
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.4
31.3
111
290
H02AB04
ATC
methylprednisolone; systemic
5.8
31.2
101
237
A49.9
ICD-10 Finland
Bacterial infection, unspecified
6.4
31.1
91
188
H02AB06
ATC
prednisolone; systemic
4.2
30.9
214
1074
I10
ICD-10 Finland
Essential (primary) hypertension
5.1
30.8
261
1586
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.2
30.1
215
1095
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
63.3
29.8
34
6
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
28.5
29.6
40
16
M10
ICD-10 Finland
Gout
10.8
29.6
59
66
A10BH05
ATC
linagliptin; oral
10.1
29.0
60
72
I50.0
ICD-10 Finland
Congestive heart failure
6.9
28.9
78
143
349
Kela drug reimbursment
Febuxostat
+∞
28.6
27
*
C08CA13
ATC
lercanidipine; oral
5.2
28.4
103
272
C09CA01
ATC
losartan; oral
4.2
28.2
142
519
C09AA02
ATC
enalapril; systemic
4.3
28.0
133
461
Z49.2
ICD-10 Finland
Other dialysis
42.1
27.7
34
9
B05DB
ATC
Hypertonic solutions
68.5
27.5
31
5
KA1AE
NOMESCO Finland
Kidney ultrasound examination
16.9
27.5
44
30
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
5.5
27.4
91
216
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
106.2
27.1
29
*
M13.9
ICD-10 Finland
Arthritis, unspecified
9.2
27.1
59
77
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
10.1
26.7
55
65
L04AA01
ATC
[U] ciclosporin; systemic
34.5
26.5
34
11
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
79.4
26.3
29
*
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
7.9
26.1
63
97
196
Kela drug reimbursment
Paricalcitol and cinacalcet
76.5
25.2
28
*
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
98.2
25.1
27
*
B03XA01
ATC
erythropoietin; parenteral
38.0
24.8
31
9
H05BX01
ATC
cinacalcet; oral
73.5
24.2
27
*
V03AE02
ATC
sevelamer; oral
45.5
24.1
29
7
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.2
24.0
108
347
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
51.1
23.7
28
6
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
8.8
23.5
52
69
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
7.8
23.3
56
85
103
Kela drug reimbursment
Diabetes, insulin-treated
3.5
23.3
150
650
C08CA02
ATC
felodipine; oral
5.2
22.9
78
187
B01AA03
ATC
warfarin; systemic
3.6
22.8
135
545
TPH04
NOMESCO Finland
Cathetrisation of vein
3.8
22.8
120
439
I12.0
ICD-10 Finland
Hypertensive renal disease with renal failure
23.6
22.6
32
15
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
6.0
22.4
66
133
215
Kela drug reimbursment
Diabetes, non-insulin-treated
3.6
22.3
134
542
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.5
21.7
137
574
C07AG02
ATC
carvedilol; oral
6.0
21.7
64
129
JN3AD
NOMESCO Finland
Abdominal CT examination
5.6
21.4
67
145
TK820
NOMESCO Finland
Peritoneal dialysis
45.1
20.8
25
6
A10AE04
ATC
insulin glargine; parenteral
5.3
20.5
67
152
C07AB07
ATC
bisoprolol; oral
3.2
20.2
207
1208
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
3.3
19.7
131
563
ZX120
NOMESCO Finland
Intravenous
5.1
19.3
66
157
V03AE03
ATC
lanthanum carbonate; oral
58.9
19.2
22
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.4
18.9
117
474
U14
ICPC
Kidney symptom/complaint
17.6
18.7
29
18
J01DB01
ATC
cefalexin; oral
4.2
18.4
276
2052
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
4.3
17.8
72
203
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
30.9
17.7
23
8
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.6
17.3
65
170
I50.1
ICD-10 Finland
Left ventricular failure
6.1
17.3
49
93
3AC01
NOMESCO Finland
NA
27.4
17.2
23
9
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
4.2
17.0
71
205
C10AA05
ATC
atorvastatin; oral
2.8
17.0
174
966
321
Kela drug reimbursment
Paricalcitol and cinacalcet
67.1
16.9
19
*
B01AB10
ATC
tinzaparin; parenteral
5.7
16.7
50
101
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
95.2
16.7
18
*
R4110
NOMESCO Finland
Physiotherapy
3.0
16.7
124
559
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
5.2
16.7
54
120
J01FF01
ATC
clindamycin; systemic
3.1
16.6
119
524
T92
ICPC
Gout
16.6
16.5
26
17
SPAT1262
SPAT
Handing over of treatment supplies
3.3
16.3
98
379
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.4
16.3
92
341
D64.9
ICD-10 Finland
Anaemia, unspecified
4.1
15.8
67
196
A12AA12
ATC
[U] calcium acetate anhydrous; systemic
89.7
15.7
17
*
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
89.7
15.7
17
*
N25.0
ICD-10 Finland
Renal osteodystrophy
40.3
15.6
19
5
R50.9
ICD-10 Finland
Fever, unspecified
3.8
15.4
73
235
C10AA01
ATC
simvastatin; oral
2.7
15.3
196
1213
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.4
15.2
59
158
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
33.6
15.0
19
6
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
3.8
14.8
69
218
A10BB12
ATC
glimepiride; oral
4.5
14.8
55
141
A02BC02
ATC
pantoprazole; systemic
2.7
14.7
227
1550
TPX10
NOMESCO Finland
Implantation of vascular injection port
8.1
14.6
33
45
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.5
14.6
78
275
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.8
14.6
126
615
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.6
14.5
172
1006
J01MA02
ATC
ciprofloxacin; systemic
2.6
14.3
161
912
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
44.7
14.2
17
*
N02AX02
ATC
tramadol; systemic, rectal
2.5
13.8
167
981
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.0
13.6
95
403
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.6
13.5
126
637
WW200
NOMESCO Finland
Immunization
8.5
13.4
29
37
TK810
NOMESCO Finland
Hemofiltration
23.8
13.0
18
8
L28
ICPC
Limited function/disability (L)
3.2
13.0
78
296
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
14.9
12.9
21
15
R06.0
ICD-10 Finland
Dyspnoea
2.7
12.9
105
488
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
7.4
12.7
30
44
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
4.4
12.7
47
120
N03.0
ICD-10 Finland
Chronic nephritic syndrome, minor glomerular abnormality
+∞
12.6
12
*
N02BE01
ATC
paracetamol; systemic, rectal
3.5
12.6
278
2228
E87.5
ICD-10 Finland
Hyperkalaemia
12.4
12.5
22
19
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
8.0
12.5
28
38
S97
ICPC
Chronic ulcer skin
4.5
12.2
44
109
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.3
12.2
70
255
L04AX01
ATC
azathioprine; systemic
6.4
12.2
32
55
T90
ICPC
Diabetes non-insulin dependent
2.6
12.1
109
531
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
5.8
12.1
34
64
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
11.2
12.0
22
21
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
4.1
11.9
48
133
A10BH01
ATC
sitagliptin; oral
3.7
11.8
55
172
B01AC04
ATC
clopidogrel; oral
2.8
11.8
88
384
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
6.0
11.7
32
58
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
10.7
11.7
22
22
N04.1
ICD-10 Finland
Nephrotic syndrome, focal and segmental glomerular lesions
67.5
11.7
13
*
C07AB02
ATC
metoprolol; systemic
2.6
11.5
102
491
D638, N189
ICD-10 Finland
NA
+∞
11.5
11
*
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
124.3
11.5
12
*
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
36.5
11.4
14
*
Q61.3
ICD-10 Finland
Polycystic kidney, unspecified
36.5
11.4
14
*
K65.0
ICD-10 Finland
Acute peritonitis
17.9
11.3
17
10
N18
ICD-10 Finland
Chronic kidney disease
17.9
11.3
17
10
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
5.2
11.3
35
74
L17
ICPC
Foot/toe symptom/complaint
2.6
11.3
99
475
R60.0
ICD-10 Finland
Localized oedema
3.4
11.2
58
197
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
4.6
11.1
39
94
C02CA01
ATC
prazosin; oral
7.4
11.1
26
38
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
2.7
11.1
93
431
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
5.7
10.9
31
59
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.4
10.9
117
622
J01MA14
ATC
moxifloxacin; systemic
3.6
10.8
51
161
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
4.6
10.8
38
92
PB1DE
NOMESCO Finland
Upper extremity arteries ultrasound examination with Doppler method
22.4
10.8
15
7
A10AE05
ATC
insulin detemir; parenteral
4.8
10.7
36
83
C03DA01
ATC
spironolactone; oral
3.1
10.7
63
234
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
62.1
10.7
12
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.4
10.6
109
565
ZXA00
NOMESCO Finland
Right side
2.4
10.6
114
604
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.7
10.6
36
84
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.3
10.5
128
719
Z94.9
ICD-10 Finland
Transplanted organ and tissue status, unspecified
113.6
10.5
11
*
WW500
NOMESCO Finland
Blood transfusion
5.6
10.5
30
58
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
9.3
10.4
21
24
RD210
NOMESCO Finland
NA
11.2
10.4
19
18
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
4.5
10.4
37
91
JN4AD
NOMESCO Finland
Body CT examination
3.8
10.3
45
133
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
24.3
10.3
14
6
ZXA05
NOMESCO Finland
Left side
2.4
10.1
108
569
A12BA01
ATC
potassium chloride; oral
4.3
10.0
37
94
N18.4
ICD-10 Finland
Chronic kidney disease, stage 4
41.5
10.0
12
*
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
8.6
10.0
21
26
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
27.0
9.9
13
5
B01AB05
ATC
enoxaparin; parenteral
2.3
9.9
118
654
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
6.6
9.6
24
39
R11
ICD-10 Finland
Nausea and vomiting
3.9
9.6
39
109
207
Kela drug reimbursment
Chronic arrhythmias
2.6
9.6
76
341
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
18.2
9.5
14
8
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
31.1
9.5
12
*
N08.2
ICD-10 Finland
Glomerular disorders in blood diseases and disorders involving the immune mechanism
103.0
9.5
10
*
A10AA02
ATC
NA
6.8
9.4
23
36
N03.8
ICD-10 Finland
Chronic nephritic syndrome, other
+∞
9.4
9
*
E21.1
ICD-10 Finland
Secondary hyperparathyroidism, not elsewhere classified
+∞
9.4
9
*
XCK10
NOMESCO Finland
Photography of fundus of eye
3.3
9.4
49
168
B99
ICD-10 Finland
Other and unspecified infectious diseases
7.1
9.3
22
33
M79.6
ICD-10 Finland
Pain in limb
2.2
9.2
119
679
WX892
NOMESCO Finland
Monitored bed care
3.4
9.2
46
152
C01DA14
ATC
isosorbide mononitrate; oral
2.5
9.2
83
398
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
10.5
9.1
17
17
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.6
9.1
75
339
A41.9
ICD-10 Finland
Sepsis, unspecified
5.2
8.9
27
56
C09CA06
ATC
candesartan; oral
2.5
8.9
81
389
XF400
NOMESCO Finland
ECG with 12 standard connections
2.5
8.9
79
375
I20.09
ICD-10 Finland
Unstable angina
3.8
8.8
37
106
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
3.7
8.8
39
117
K07
ICPC
Swollen ankles/oedema
4.9
8.7
28
62
D89.80
ICD-10 Finland
Immunoglobulin A (IgA) deposits in organisms
51.4
8.7
10
*
R53
ICD-10 Finland
Malaise and fatigue
2.5
8.6
75
351
J01MA12
ATC
levofloxacin; systemic
2.4
8.6
83
408
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.2
8.5
47
165
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
5.3
8.5
25
50
H3603, E103
ICD-10 Finland
NA
20.7
8.5
12
6
UJF32
NOMESCO Finland
Coloscopy
2.2
8.5
100
544
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.6
8.5
67
297
A10AA01
ATC
NA
8.2
8.5
18
23
E86
ICD-10 Finland
Volume depletion
6.5
8.5
21
34
H05BX02
ATC
paricalcitol; systemic
92.4
8.5
9
*
N03.3
ICD-10 Finland
Chronic nephritic syndrome, diffuse mesangial proliferative glomerulonephritis
92.4
8.5
9
*
58209
ICD-8 Finland
Chronic nephritis, Unspecified
92.4
8.5
9
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.9
8.4
34
95
RS220
NOMESCO Finland
NA
11.2
8.4
15
14
N11.8
ICD-10 Finland
Other chronic tubulo-interstitial nephritis
+∞
8.4
8
*
Z99.2
ICD-10 Finland
Dependence on renal dialysis
+∞
8.4
8
*
AA1AD
NOMESCO Finland
CT of head and brain
2.3
8.4
95
506
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
6.2
8.1
21
36
J01DA01
ATC
[U] cefalexin; systemic
2.0
8.1
193
1392
WX722
NOMESCO Finland
PEEP
4.1
8.1
31
82
WX610
NOMESCO Finland
Patient controlled analgesia
34.3
8.1
10
*
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
4.9
8.0
25
54
I50
ICD-10 Finland
Heart failure
5.7
8.0
22
41
E66.8
ICD-10 Finland
Other obesity
6.4
8.0
20
33
M01AB01
ATC
indometacin; systemic, rectal
3.1
8.0
44
155
WX202
NOMESCO Finland
Supraclavicular plexus blockade
11.2
7.9
14
13
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.6
7.8
26
60
AN1
HP
Coronary angiography
2.6
7.8
63
281
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
4.4
7.8
27
65
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
15.5
7.8
12
8
R31
ICD-10 Finland
Unspecified haematuria
2.8
7.8
51
202
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.7
7.8
57
241
V03AE04
ATC
calcium acetate and magnesium carbonate; systemic
46.1
7.7
9
*
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
5.4
7.7
22
43
H43.1
ICD-10 Finland
Vitreous haemorrhage
5.7
7.7
21
39
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
6.0
7.7
20
35
A08
ICPC
Swelling
4.7
7.6
25
57
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
25.7
7.6
10
*
C09BA02
ATC
enalapril and diuretics; systemic
3.0
7.6
46
172
WX002
NOMESCO Finland
Sedation and analgesia
2.3
7.6
77
388
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
7.5
102
585
N18.3
ICD-10 Finland
Chronic kidney disease, stage 3
81.9
7.4
8
*
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
81.9
7.4
8
*
R4190
NOMESCO Finland
Nutritional therapy
5.4
7.4
21
41
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
11.2
7.4
13
12
A10BH02
ATC
vildagliptin; oral
6.1
7.3
19
33
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.2
7.3
37
124
L04AA05
ATC
[U] tacrolimus; systemic
+∞
7.3
7
*
7151
FHL
Kidney transplantation
+∞
7.3
7
*
N03.1
ICD-10 Finland
Chronic nephritic syndrome, focal and segmental glomerular lesions
+∞
7.3
7
*
C08DB01
ATC
diltiazem; oral
3.4
7.3
34
107
KBV00
NOMESCO Finland
Insertion of stent into ureter
16.2
7.3
11
7
SPAT1255
SPAT
Intravenous administration of medicine
3.7
7.2
30
86
A41.8
ICD-10 Finland
Other specified sepsis
8.2
7.2
15
19
PG5AC
NOMESCO Finland
Contrast examination of injection gate to artery or vein
30.8
7.2
9
*
PBU84
NOMESCO Finland
Plastic repair of arteriovenous fistula from artery of upper extremity
30.8
7.2
9
*
A28
ICPC
Limited function/disability NOS
2.3
7.2
69
339
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
20.6
7.2
10
5
I42.0
ICD-10 Finland
Dilated cardiomyopathy
5.0
7.2
22
47
S18
ICPC
Laceration/cut
1.9
7.2
144
958
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
2.1
7.1
93
524
R80
ICD-10 Finland
Isolated proteinuria
12.4
7.1
12
10
TPH07
NOMESCO Finland
Cathetrisation of artery
2.6
7.1
54
234
C02EA02
ATC
NA
3.7
7.0
30
88
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
3.7
7.0
30
88
WX882
NOMESCO Finland
High dependency care
4.8
7.0
22
48
N02AJ06
ATC
codeine and paracetamol; systemic
2.0
7.0
115
708
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
6.1
7.0
18
31
UJF30
NOMESCO Finland
Ileoscopy through colon
3.1
7.0
39
139
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
3.4
6.9
32
101
E66.00
ICD-10 Finland
Metabolic syndrome
3.6
6.9
30
90
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
6.4
6.9
17
28
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
4.9
6.8
21
45
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.5
6.8
57
258
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
3.1
6.8
36
125
K65.9
ICD-10 Finland
Peritonitis, unspecified
40.9
6.8
8
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.7
6.8
47
194
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
4.1
6.8
25
65
UKC02
NOMESCO Finland
Cystoscopy
2.2
6.7
70
356
B02.9
ICD-10 Finland
Zoster without complication
3.7
6.7
28
81
C09AA05
ATC
ramipril; oral
2.0
6.7
104
628
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.4
6.7
31
98
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
12.6
6.6
11
9
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.5
6.6
29
88
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
5.9
6.5
17
30
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
4.3
6.5
23
57
201
Kela drug reimbursment
Chronic cardiac insufficiency
3.4
6.5
30
94
J01CA04
ATC
amoxicillin; systemic
2.0
6.5
232
1865
SAA03
NOMESCO Finland
Extended examination of mouth
2.0
6.5
107
656
SPAT1254
SPAT
Administration of medicine
2.3
6.5
60
288
N02AA05
ATC
oxycodone; systemic
2.3
6.5
60
288
E66.01
ICD-10 Finland
Obesity due to excess calories
3.8
6.5
26
73
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
2.0
6.5
99
590
N05.9
ICD-10 Finland
Unspecified nephritic syndrome, unspecified
71.2
6.4
7
*
H02AB07
ATC
prednisone; oral
2.4
6.4
57
266
SPAT1325
SPAT
Vaccination
1.9
6.4
119
763
WX203
NOMESCO Finland
Infraclavicular plexus blockade
5.7
6.4
17
31
H36.00
ICD-10 Finland
Diabetic background retinopathy
8.4
6.4
13
16
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.6
6.3
46
192
Q61.0
ICD-10 Finland
Congenital single renal cyst
+∞
6.3
6
*
WW400
NOMESCO Finland
Plasmaferesis
+∞
6.3
6
*
5828A
ICD-9 Finland
Chronic glomerulonephritis, With other specified pathological lesion in kidney[GLOMERULONEPHRITIS CHRONICA ALIA DEF,EI NEFR SDR]
+∞
6.3
6
*
5850B
ICD-9 Finland
Chronic renal failure[INSUFFICIENTIA RENIS CHRONICA CUM URAEMIA]
+∞
6.3
6
*
BBA50
NOMESCO Finland
Total parathyroidectomy
+∞
6.3
6
*
GD1UN
NOMESCO Finland
Lung circulation SPECT
27.3
6.3
8
*
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
27.3
6.3
8
*
NHQ40
NOMESCO Finland
Amputation of toe
6.5
6.2
15
24
SPAT1099
SPAT
Measurement of blood pressure with Doppler ultrasound device
4.1
6.2
23
60
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.9
6.2
19
41
C10AX09
ATC
ezetimibe; oral
2.5
6.2
49
218
E0000UV
ATC
NA
1.9
6.1
121
788
FM1LE
NOMESCO Finland
Combined ultrasound and EKG examination of heart with tolerance test
12.9
6.1
10
8
SPAT1263
SPAT
Sampling
1.8
6.1
131
879
R02
ICPC
Shortness of breath/dyspnoea
2.5
6.1
48
213
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
244
254
31.48
240.78
26.7
7.2
17.1
10.9
mmol/l
19.84
237
240
214
214
25.29
212.90
13.4
3.9
192.5
85.7
ng/l
14.93
199
189
253
387
22.64
188.59
27.2
5.6
1.2
1.0
mmol/l
13.95
246
359
285
739
18.66
130.94
8.9
2.6
3642.3
7060.9
umol/l
0.56
277
632
216
421
12.33
124.94
10.0
2.4
22.4
22.8
%
0.15
201
367
176
279
12.00
119.76
14.3
4.0
1.1
1.7
mmol/l
1.14
153
220
77
45
21.83
96.67
9.6
8.3
352.5
106.0
iu/ml
—
24
8
113
143
11.34
89.12
13.5
4.1
23.3
24.1
mmol/l
1.59
105
132
113
157
10.28
82.53
2.2
1.9
1.6
1.5
g/l
0.90
105
137
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
85
102
10.78
68.73
4.2
2.1
0.4
0.4
u/ml
0.12
47
49
70
67
12.90
66.12
1.8
1.3
—
—
—
0
0
250
943
7.24
65.67
10.3
3.8
38.4
9.5
mg/mmol
7.22
231
609
56
38
17.45
64.55
2.7
1.5
113.8
93.3
u/ml
—
16
7
262
1067
7.34
62.02
11.0
3.3
—
—
—
0
0
144
361
6.18
58.60
3.7
4.3
245.0
241.4
u/l
0.14
137
343
280
1277
7.76
56.32
18.6
4.7
33.7
34.9
g/l
3.53
273
1190
54
44
14.40
56.04
1.6
1.2
325.7
319.6
u/ml
0.02
43
23
252
1060
6.32
55.23
10.0
2.6
281.9
163.5
ug/l
8.02
246
965
231
907
5.83
54.86
8.2
3.1
6.1
7.8
mmol/l
11.28
221
741
249
1043
6.18
54.65
4.7
2.2
74.9
77.0
nmol/l
0.58
241
912
53
46
13.46
52.87
1.6
1.2
—
—
—
0
0
60
65
10.99
51.67
1.9
1.6
12582.9
11455.9
e6/l
0.12
47
48
213
818
5.29
50.91
9.2
3.3
0.3
0.6
e6/l
1.60
192
614
102
216
6.32
48.86
9.2
3.3
1.5
1.7
mmol/l
0.16
67
161
284
1429
6.99
47.47
39.5
6.8
1.2
1.2
mmol/l
0.51
256
1200
105
258
5.44
42.22
3.1
2.7
63.1
66.1
g/l
2.86
97
235
150
496
4.62
41.75
7.2
3.1
1.8
1.1
e6/l
0.87
109
285
146
513
4.24
36.66
6.2
2.9
0.8
1.0
e6/l
0.28
106
300
87
206
5.33
36.07
2.5
1.6
—
—
—
0
0
143
512
4.09
34.66
2.9
1.8
—
—
—
0
0
28
16
18.98
34.56
1.2
1.3
—
—
—
0
0
250
1313
4.42
34.51
30.3
6.1
1.2
1.2
mmol/l
1.47
241
1183
84
206
5.09
33.25
6.9
2.8
26.2
64.8
ml/min/173m2
26.19
58
93
176
747
3.81
32.89
3.4
2.0
3.4
3.1
mg/l
0.87
162
648
153
604
3.79
31.65
2.4
1.7
1172.9
1176.2
nmol/l
0.01
138
453
59
111
6.22
31.17
2.4
3.8
49.9
38.2
mg/l
0.96
46
92
30
24
13.61
31.02
1.5
1.1
12461.8
181147.9
e6/l
0.64
18
15
44
61
8.14
30.85
3.7
2.2
125.5
129.1
g/l
0.33
38
43
58
111
6.09
30.07
2.4
3.8
75.6
121.9
mg/l
0.38
44
91
27
19
15.35
29.97
1.1
1.2
—
—
—
0
0
100
308
4.18
29.31
5.1
3.4
—
—
—
0
0
235
1288
3.67
27.99
12.3
6.0
20.6
25.9
%
13.20
229
1203
232
1265
3.63
27.79
11.6
5.8
63.5
58.5
%
9.28
226
1187
200
999
3.43
27.56
5.7
3.1
7123.5
1663.0
ng/l
8.05
190
868
279
1723
4.45
27.44
12.7
4.9
7.9
6.9
mmol/l
5.99
272
1630
105
362
3.75
25.88
2.6
1.8
—
—
—
0
0
105
363
3.74
25.76
2.6
1.9
—
—
—
0
0
258
1547
3.77
25.68
14.1
9.1
4.9
4.3
e9/l
4.43
239
1355
39
58
7.47
25.63
4.2
2.1
15.9
15.7
%
0.08
34
27
220
1222
3.27
24.29
2.9
2.1
94.5
92.6
pmol/l
0.22
135
659
28
6
50.66
23.70
16.3
7.0
5.4
7.6
mmol/l
—
28
6
32
42
8.31
23.34
1.4
1.2
—
—
—
0
0
25
24
11.16
22.94
1.3
1.1
73.6
53.9
u/l
0.48
16
16
41
76
6.00
21.77
2.5
1.4
—
—
—
0
0
33
49
7.35
21.64
1.5
1.1
—
—
—
0
0
180
936
2.96
21.53
6.7
3.4
2.3
2.3
mmol/l
0.00
169
807
43
86
5.58
21.06
2.0
1.2
—
—
—
0
0
99
373
3.33
20.77
6.9
7.5
5.0
5.1
kpa
0.32
92
355
99
374
3.32
20.67
6.9
7.5
10.6
11.4
kpa
1.12
90
358
98
369
3.33
20.56
7.0
7.6
-0.1
1.0
mmol/l
1.19
74
301
217
1271
2.96
20.43
6.7
4.2
—
—
—
0
0
26
31
9.00
20.40
1.5
1.3
68.3
64.6
%
0.17
20
24
143
685
2.88
19.49
4.3
2.7
—
—
—
0
0
217
1291
2.88
19.48
9.1
3.7
0.0
0.0
estimate
0.00
48
240
217
1305
2.83
18.83
9.2
3.8
0.0
0.0
estimate
0.00
50
227
107
452
3.00
18.19
41.6
25.4
1.8
1.3
inr
1.18
13
58
50
129
4.37
18.07
2.7
1.8
3.7
3.7
g/l
0.08
38
94
50
129
4.37
18.07
2.7
1.8
—
—
—
0
0
50
129
4.37
18.07
2.7
1.8
7.7
7.3
g/l
0.91
38
99
213
1289
2.75
17.91
13.1
5.1
0.0
0.0
estimate
0.00
52
242
296
2145
3.94
17.83
21.5
7.8
93.0
79.2
u/l
2.37
289
2005
21
23
9.67
17.49
1.4
1.3
20.5
30.0
%
0.57
16
17
34
65
5.70
17.41
2.3
1.6
—
—
—
0
0
38
83
5.03
16.79
1.5
1.6
—
—
—
0
0
89
354
3.05
16.68
1.3
1.3
10.0
10.8
u/ml
0.03
28
140
28
46
6.54
16.66
2.4
1.7
—
—
—
0
0
38
84
4.97
16.56
3.6
2.2
144.4
92.1
ug/min
0.39
26
45
23
31
7.89
16.30
1.1
1.1
—
—
—
0
0
33
67
5.35
15.81
2.3
1.6
—
—
—
0
0
59
191
3.53
15.43
2.0
1.4
—
—
—
0
0
20
7
30.22
15.36
1.0
1.0
—
—
—
0
0
21
29
7.65
14.56
1.6
1.4
—
—
—
0
0
44
121
4.03
14.53
2.9
1.8
3.2
3.2
g/l
0.09
38
95
76
300
2.97
14.26
8.1
8.4
114.1
120.3
g/l
1.46
71
293
193
1202
2.40
13.95
6.8
4.0
137.0
54.5
ng/l
1.14
170
924
86
375
2.73
13.34
1.4
1.2
31.6
33.8
iu/ml
0.08
30
115
30
66
4.89
13.10
2.4
1.4
—
—
—
0
0
116
591
2.46
13.00
7.7
3.9
75.2
324.4
ng/l
2.19
107
498
139
769
2.37
12.94
2.2
1.6
19.5
20.3
nmol/l
0.20
132
651
52
176
3.31
12.59
6.2
10.5
23.0
24.4
mmol/l
1.73
46
166
41
119
3.78
12.53
2.4
2.3
272.6
721.0
ug/l
0.65
41
113
22
38
6.12
12.43
1.9
1.4
—
—
—
0
0
28
62
4.83
12.13
1.6
1.6
—
—
—
0
0
29
67
4.64
11.94
3.0
1.6
—
—
—
0
0
264
1960
2.55
11.92
7.4
4.2
30.4
13.2
mm/h
19.80
253
1784
111
575
2.38
11.82
2.8
1.7
1.4
1.5
mg/l
0.07
91
448
14
15
9.69
11.73
1.2
1.2
73.8
111.1
u/l
—
14
10
55
201
3.07
11.70
2.3
1.7
—
—
—
0
0
39
117
3.64
11.34
2.9
2.1
41.5
39.2
u/l
0.31
34
103
14
16
9.08
11.19
1.5
1.5
5.1
23.9
u/l
—
8
9
27
64
4.50
10.77
1.6
1.4
—
—
—
0
0
27
64
4.50
10.77
1.6
1.4
—
—
—
0
0
147
885
2.16
10.69
4.2
3.4
50.4
33.8
u/l
0.60
142
844
25
56
4.74
10.67
1.6
1.5
—
—
—
0
0
22
46
5.04
10.16
1.4
1.5
—
—
—
0
0
22
48
4.83
9.67
1.6
1.5
—
—
—
0
0
20
41
5.12
9.43
1.6
1.5
—
—
—
0
0
15
23
6.78
9.43
1.5
1.6
—
—
—
0
0
301
2504
2.76
8.64
14.4
6.4
45.0
41.0
mmol/mol
6.06
295
2301
15
27
5.77
8.09
4.2
2.2
—
—
—
0
0
240
1843
2.03
8.03
4.4
3.6
14.8
15.0
pmol/l
0.72
228
1631
48
200
2.63
7.93
9.4
6.1
23.8
24.3
mmol/l
0.37
42
187
309
2642
2.86
7.69
63.6
16.2
28.5
27.1
mg/l
0.37
301
2161
57
262
2.41
7.67
4.7
2.5
44.8
36.5
u/l
0.70
52
222
21
54
4.08
7.55
2.4
1.4
—
—
—
0
0
21
56
3.93
7.19
1.8
1.5
—
—
—
0
0
149
1002
1.87
7.19
10.5
4.0
—
—
—
0
0
33
120
2.94
7.03
2.9
3.2
—
—
—
0
0
294
2484
2.36
7.01
7.6
4.3
1.7
1.3
mmol/l
10.04
282
2244
12
20
6.18
6.95
1.8
1.3
—
—
—
0
0
276
2295
2.08
6.53
56.3
17.9
34.0
39.5
%
10.07
176
1515
94
560
1.94
6.46
3.5
3.2
2.5
2.5
mmol/l
3.38
83
487
17
42
4.21
6.43
4.8
2.3
3.7
4.9
e9/l
1.34
17
42
56
276
2.23
6.39
2.8
2.4
0.2
0.2
g/l
1.44
51
257
33
127
2.77
6.35
3.3
1.7
—
—
—
0
0
102
630
1.88
6.27
1.9
1.9
479.7
7812930.2
pmol/l
0.50
93
512
6
0
+∞
6.27
4.2
0.0
—
—
—
0
0
22
68
3.39
6.11
1.8
1.5
266.1
264.1
ug/g
0.02
17
43
15
35
4.44
6.09
1.3
1.3
2.9
1.9
u/ml
—
9
13
30
114
2.79
5.91
2.4
1.6
—
—
—
0
0
17
45
3.92
5.89
6.1
2.8
56.2
59.6
%
0.54
17
45
297
2569
2.23
5.87
8.0
4.7
1.2
1.4
mmol/l
10.54
285
2332
298
2588
2.23
5.72
8.1
4.8
4.0
4.4
mmol/l
9.40
287
2365
11
21
5.38
5.56
2.3
1.2
—
—
—
0
0
11
21
5.38
5.56
2.3
1.2
—
—
—
0
0
108
711
1.76
5.26
9.9
3.9
0.0
0.0
estimate
0.50
42
232
14
35
4.13
5.22
2.6
1.4
—
—
—
0
0
21
71
3.09
5.08
1.5
1.4
—
—
—
0
0
301
2654
2.17
5.07
8.5
5.3
2.1
2.6
mmol/l
16.74
290
2409
14
36
4.01
5.04
2.6
1.4
—
—
—
0
0
14
36
4.01
5.04
2.5
1.4
—
—
—
0
0
14
36
4.01
5.04
2.6
1.4
—
—
—
0
0
14
36
4.01
5.04
2.6
1.4
—
—
—
0
0
12
28
4.41
4.86
3.1
1.9
—
—
—
0
0
12
28
4.41
4.86
3.1
1.9
—
—
—
0
0
12
28
4.41
4.86
3.1
1.9
—
—
—
0
0
14
37
3.90
4.86
2.6
1.4
—
—
—
0
0
272
2331
1.83
4.79
5.9
4.4
2.4
2.0
mu/l
3.30
258
2085
175
1336
1.64
4.78
3.3
2.3
—
—
—
0
0
12
29
4.25
4.66
2.1
1.6
—
—
—
0
0
7
5
14.25
4.59
1.0
1.0
1616.0
1392.0
miu/ml
—
7
5
12
30
4.11
4.47
2.6
1.9
—
—
—
0
0
20
72
2.89
4.36
1.5
1.2
—
—
—
0
0
20
73
2.85
4.26
1.5
1.2
—
—
—
0
0
24
100
2.51
3.99
1.6
1.3
—
—
—
0
0
12
33
3.73
3.95
2.6
1.8
—
—
—
0
0
204
1669
1.56
3.80
5.7
3.3
88.0
53.3
u/l
1.94
196
1542
13
39
3.43
3.80
1.5
1.3
1.8
7.9
u/ml
—
6
22
308
2812
2.01
3.58
72.9
19.5
222.5
84.6
umol/l
40.89
308
2812
8
13
6.27
3.52
1.3
1.1
—
—
—
0
0
8
13
6.27
3.52
1.3
1.1
—
—
—
0
0
6
6
10.15
3.51
1.0
1.2
96.8
106.7
%
—
6
6
14
47
3.06
3.45
1.1
1.1
—
—
—
0
0
9
18
5.10
3.39
1.4
1.3
—
—
—
0
0
11
32
3.52
3.36
1.2
1.2
—
—
—
0
0
71
469
1.65
3.27
1.3
1.2
0.8
1.2
u/ml
0.97
17
126
10
28
3.65
3.22
1.1
1.3
—
—
—
0
0
9
20
4.59
3.13
2.6
1.3
—
—
—
0
0
9
20
4.59
3.13
2.6
1.3
—
—
—
0
0
12
39
3.15
3.12
2.3
2.0
33.0
32.9
pg
0.02
12
39
7
12
5.93
3.03
3.0
2.0
—
—
—
0
0
7
12
5.93
3.03
2.9
2.0
—
—
—
0
0
7
12
5.93
3.03
3.0
2.0
—
—
—
0
0
7
12
5.93
3.03
3.0
2.0
—
—
—
0
0
280
2517
1.64
3.02
57.7
15.2
34.6
75.8
ml/min/173m2
96.89
264
2099
9
21
4.37
3.01
1.0
1.3
—
—
—
0
0
8
17
4.79
2.93
1.4
1.1
—
—
—
0
0
7
13
5.47
2.88
4.0
1.9
100.4
99.2
%
—
7
13
7
13
5.47
2.88
1.6
1.3
—
—
—
0
0
14
53
2.71
2.83
1.1
1.2
—
—
—
0
0
6
11
5.53
2.55
3.0
2.1
—
—
—
0
0
6
11
5.53
2.55
3.0
2.1
—
—
—
0
0
6
12
5.07
2.41
1.7
1.3
—
—
—
0
0
6
12
5.07
2.41
3.2
2.0
—
—
—
0
0
5
8
6.32
2.38
1.2
1.3
—
—
—
0
0
6
13
4.68
2.28
1.5
2.0
—
—
—
0
0
6
18
3.37
1.75
6.3
4.4
—
—
—
0
0
46
319
1.51
1.74
2.5
4.4
3.9
47.5
ug/l
1.08
40
268
5
14
3.61
1.62
1.0
1.2
6.0
7.8
mmol/l
—
5
14
5
14
3.61
1.62
4.2
1.6
1370.4
1144.2
u/ml
—
5
14
5
15
3.37
1.53
1.6
1.1
—
—
—
0
0
23
139
1.70
1.52
1.1
1.3
—
45.1
—
0
12
5
16
3.16
1.44
2.8
1.5
1.0
1.0
g/l
—
5
16
9
41
2.23
1.38
1.0
1.0
—
—
—
0
0
10
48
2.12
1.29
1.3
1.3
—
46.2
—
0
5
8
160
0.49
1.28
1.1
1.8
—
—
—
0
0
6
25
2.42
1.25
1.0
1.2
—
—
—
0
0
6
25
2.42
1.25
1.0
1.2
—
—
—
0
0
6
25
2.42
1.25
1.0
1.2
—
—
—
0
0
6
25
2.42
1.25
1.0
1.2
—
—
—
0
0
6
25
2.42
1.25
1.0
1.2
—
—
—
0
0
275
2590
1.32
1.23
9.0
5.0
6.7
6.1
mmol/l
4.83
264
2336
11
57
1.96
1.18
1.3
1.1
—
16.8
—
0
5
8
41
1.97
1.09
1.1
1.1
—
—
—
0
0
7
33
2.14
1.06
1.0
1.3
—
—
—
0
0
9
48
1.90
1.01
1.3
1.3
10.8
2464.8
e6/l
—
9
39
9
49
1.86
0.99
1.2
1.3
—
—
—
0
0
7
37
1.91
0.94
2.1
1.3
—
—
—
0
0
173
1575
1.20
0.92
4.2
5.2
2.4
2.6
ug/l
0.13
164
1402
8
42
1.93
0.89
3.9
4.0
—
—
—
0
0
6
30
2.02
0.87
1.0
1.2
9.6
7.7
mmol/l
—
6
21
16
106
1.53
0.80
1.1
1.2
18.6
102.7
iu/ml
—
6
32
5
24
2.10
0.75
1.0
1.1
—
—
—
0
0
5
25
2.01
0.73
1.0
1.1
—
—
—
0
0
5
28
1.80
0.66
1.0
1.1
—
—
—
0
0
8
49
1.65
0.62
1.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
34
275
1.26
0.58
1.2
1.3
—
—
—
0
0
13
90
1.46
0.56
1.0
1.0
—
—
—
0
0
33
271
1.24
0.51
1.8
1.8
1.9
1.6
%
0.68
26
231
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
79
725
1.12
0.34
2.0
1.7
1.8
1.3
mmol/l
3.45
73
609
8
62
1.30
0.28
1.4
1.3
—
—
—
0
0
87
921
0.93
0.22
2.9
3.1
1.0
0.8
ug/l
0.80
68
629
5
42
1.19
0.21
3.8
1.6
14.0
16.1
ug/l
—
5
42
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.8
—
65.9
—
0
14
31
341
0.90
0.18
27.9
7.7
—
—
—
0
0
11
91
1.22
0.18
1.4
1.7
—
—
—
0
0
10
82
1.23
0.17
1.5
1.8
43.0
45.7
nmol/l
—
10
76
7
63
1.11
0.17
1.9
1.5
—
—
—
0
0
18
160
1.13
0.14
1.4
1.4
—
—
—
0
0
12
103
1.17
0.14
1.4
1.9
—
—
—
0
0
125
1275
0.97
0.08
3.6
4.5
27.0
21.2
%
3.72
69
623
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
8.4
—
0
9
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint GOUT_KIDNEY and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| GOUT_KIDNEY | 3.249 [2.27, 4.66] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.047 |
During the follow-up period (1.1.1998 — 31.12.2019), 269 out of 519 females with GOUT_KIDNEY died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| GOUT_KIDNEY | 3.409 [2.41, 4.82] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 471 out of 1000 males with GOUT_KIDNEY died.
Mortality risk
Mortality risk for people of age
years, who have GOUT_KIDNEY.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.325% | 0.617% |
| 5 | 1.813% | 4.031% |
| 10 | 4.542% | 9.412% |
| 15 | 8.29% | 17.3% |
| 20 | 14.068% | 28.218% |
Relationships between endpoints
↥Index endpoint: GOUT_KIDNEY – Gout due to impairment of renal function
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data