Nightmares

F5_NIGHTMARES

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — F51.5 Cause of death: ICD-10 — F51.5 2 out of 7 registries used, show all original rules.	75
4. Check minimum number of events None	75
5. Include endpoints None	75
6. Filter based on genotype QC (FinnGen only)	75

Control definitions (FinnGen only)

Control exclude: F5_SLEEP

Extra metadata

First used in FinnGen datafreeze: DF5

NAME	F5_NIGHTMARES
CONTROL_EXCLUDE	F5_SLEEP
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	F515
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	F515
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Nightmares based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	528	298	223
Only index persons	483	282	201
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	30.77	29.91	31.65
Only index persons	31.02	29.91	32.57

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	75	56	19
Unadjusted period prevalence (%)	0.02	0.02	0.01
Median age at first event (years)	43.79	36.41	65.55

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
65: Matched controls
651

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

F51.5

ICD-10 Finland

Nightmares

+∞

93.3

N05AH04

ATC

quetiapine; oral

10.7

15.3

IAB13

NOMESCO Finland

Psychiatric sleep disorder consultation

+∞

12.9

F51.9

ICD-10 Finland

Nonorganic sleep disorder, unspecified

144.6

11.8

F33.2

ICD-10 Finland

Recurrent depressive disorder, current episode severe without psychotic symptoms

27.2

11.3

ICB01

NOMESCO Finland

Psychiatric treatment plan, standard

23.8

10.9

IEY05

NOMESCO Finland

Dedicated profession-specific psychiatric intervention, individual

18.8

10.7

N04BC05

ATC

pramipexole; oral

19.4

9.5

N06AX11

ATC

mirtazapine; oral

5.2

9.1

138

G25.8

ICD-10 Finland

Other specified extrapyramidal and movement disorders

32.5

8.8

F51.0

ICD-10 Finland

Nonorganic insomnia

6.8

8.6

IEY18

NOMESCO Finland

Psychiatric sleep coaching, individual

+∞

8.5

ICZ03

NOMESCO Finland

Participation in compiling a psychiatric treatment plan

15.9

8.3

F33.10

ICD-10 Finland

Recurrent depression, moderate episode without somatic syndrome

7.8

7.0

IAA01

NOMESCO Finland

Assessment of need for psychiatric treatment

19.3

7.0

IBZ01

NOMESCO Finland

Profession-specific psychiatric evaluation

19.3

7.0

N06AX16

ATC

venlafaxine; oral

5.2

6.9

F43.1

ICD-10 Finland

Post-traumatic stress disorder

16.6

6.6

F33.9

ICD-10 Finland

Recurrent depressive disorder, unspecified

11.0

6.6

IGY01

NOMESCO Finland

Accelerated psychiatric treatment contact

20.5

6.5

N03AE01

ATC

clonazepam; systemic

11.7

6.3

F32.2

ICD-10 Finland

Severe depressive episode without psychotic symptoms

7.8

6.3

N06AX05

ATC

trazodone; oral

17.1

6.1

N05AH03

ATC

olanzapine; systemic

12.8

6.0

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method

6.22

7.82

1.3

1.4

4.3

3.5

mg/l

0.12

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

187

3.83

7.65

2.7

2.8

22.5

25.9

u/l

0.95

176

(3022948) Iron [Moles/volume] in Serum or Plasma

4.04

6.57

2.2

1.8

14.3

15.6

umol/l

0.28

(3028707) Methadone [Presence] in Urine by Screen method

5.76

5.97

2.5

1.5

—

(3052851) Hemolysis interference index of Serum or Plasma

14.37

5.74

1.9

2.9

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

198

3.02

5.25

2.4

1.8

97.5

93.2

pmol/l

0.23

109

(3015736) pH of Urine

228

2.91

4.92

4.1

3.1

—

(3028300) Cannabinoids [Presence] in Urine

4.11

4.91

3.0

1.4

—

(3000764) Benzodiazepines [Presence] in Urine

4.11

4.91

3.0

1.4

—

(3027944) Amphetamines [Presence] in Urine

4.11

4.91

3.0

1.4

—

(3027008) Opiates [Presence] in Urine

4.11

4.91

3.0

1.4

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

231

2.86

4.75

6.2

1.2

mmol/l

0.07

194

(3011288) Drugs identified in Urine by Screen method

4.57

4.64

3.2

1.9

—

(3016879) Cocaine [Presence] in Urine

3.97

4.43

3.1

1.4

—

(3044889) 12 lead EKG panel

341

2.89

4.28

3.1

2.9

—

(3037467) Urinalysis macro (dipstick) panel - Urine

415

3.23

4.20

5.7

4.5

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

180

2.63

3.98

3.9

3.3

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

339

2.74

3.96

8.0

8.7

4.1

e9/l

0.06

304

(3035350) Ketones [Presence] in Urine by Test strip

280

2.52

3.68

3.8

3.4

0.0

estimate

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

3.78

3.65

2.3

1.4

—

(40758558) Short blood count panel - Blood

136

2.54

3.42

6.4

7.3

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

9.18

3.32

1.2

1.0

—

(3012544) pH of Venous blood

3.97

3.32

3.2

3.4

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

3.97

3.32

3.2

3.5

6.2

5.6

kpa

—

(3021601) Nitrite [Presence] in Urine by Test strip

280

2.38

3.30

5.2

4.9

0.0

estimate

—

(3018095) Leukocytes [#/volume] in Urine

203

2.36

3.23

4.8

3.5

68.6

44.6

e6/l

0.17

130

(3012516) Albumin [Mass/volume] in Urine

110

2.57

3.22

3.0

3.1

9.1

76.7

mg/l

1.52

(3000494) Fungus identified in Specimen by Culture

2.98

3.10

1.7

1.3

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

177

2.28

2.91

3.1

2.9

15.5

27.7

ng/l

1.25

(3019309) Folate [Moles/volume] in Red Blood Cells

2.64

2.89

1.6

1140.3

1236.0

nmol/l

0.15

(3009261) Glucose [Presence] in Urine by Test strip

284

2.20

2.81

4.0

3.5

0.0

estimate

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

2.68

2.71

1.1

1.6

—

(40768804) Tissue Pathology biopsy report

225

2.15

2.66

1.9

—

(3025941) Bacteria identified in Stool by Culture

3.34

2.64

1.1

1.2

—

(3020682) Albumin/Creatinine [Ratio] in Urine

121

2.30

2.57

3.1

3.7

1.0

11.3

mg/mmol

1.90

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

3.64

2.49

1.4

—

(3002582) Erythrocytes [#/volume] in Urine

163

2.15

2.44

4.0

3.1

27.1

435.6

e6/l

0.52

125

(1002224) Polysomnography panel

3.94

2.44

1.0

1.1

—

(3029937) Albumin [Presence] in Urine by Test strip

147

2.18

2.44

4.4

3.7

0.0

estimate

—

(36304419) Bacteria [Presence] in Urine

148

2.16

2.39

3.7

2.6

—

(3022145) Colonoscopy Study observation

2.64

2.39

1.1

1.3

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

215

2.06

2.38

3.7

3.5

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

575

2.95

2.30

5.1

3.7

2.7

2.8

mmol/l

0.57

532

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

568

2.68

2.22

4.4

3.5

4.4

4.7

mmol/l

2.10

531

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

4.56

2.19

1.5

4.2

1.1

1.2

—

(3003327) Ova and parasites identified in Stool by Light microscopy

3.45

2.16

1.8

1.5

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

4.25

2.08

1.5

1.7

—

(3000991) Gas panel - Venous blood

3.32

2.08

4.6

9.1

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

132

2.07

2.04

4.0

3.1

—

(3030467) Casts [#/volume] in Urine by Automated count

149

2.02

2.00

3.7

2.7

1.2

0.3

e6/l

0.36

112

(42870588) Differential panel, method unspecified - Blood

183

1.95

1.98

5.1

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

3.98

1.97

1.5

3.9

137.5

124.2

g/l

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

2.18

1.96

1.5

1.8

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

544

2.46

1.93

14.1

10.2

90.4

91.1

ml/min/173m2

0.12

433

(3013512) EKG study

128

2.02

1.87

3.8

3.9

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

564

2.42

1.84

4.6

3.5

1.4

1.5

mmol/l

1.35

524

(3021589) Normoblasts [#/volume] in Blood

250

1.85

1.81

10.5

8.0

0.0

e9/l

0.00

213

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.86

1.78

2.0

2.1

—

(3024354) Oxygen [Partial pressure] in Venous blood

3.11

1.77

3.3

3.7

4.3

4.6

kpa

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

2.36

1.59

1.6

2.1

—

(3025130) Human papilloma virus identified in Specimen

3.49

1.55

1.2

1.8

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

2.23

1.53

3.4

2.3

2128.5

960.8

u/l

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

162

1.81

1.52

2.2

2.1

—

(40761535) Cells panel - Urine sediment

2.55

1.52

2.7

3.3

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

2.04

1.49

3.5

2.5

6.7

137.0

ng/l

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.95

1.46

2.2

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

3.27

1.46

1.4

4.6

25.8

24.4

mmol/l

—

(3048689) Calprotectin [Mass/mass] in Stool

1.93

1.42

2.5

2.2

56.1

70.7

ug/g

0.22

(3032080) INR in Blood by Coagulation assay

174

1.76

1.41

3.1

6.1

1.0

1.1

inr

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

3.07

1.38

1.6

1.3

90.8

97.1

—

(3026008) Bacteria identified in Urine by Culture

172

1.68

1.21

2.8

2.5

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.05

1.19

1.7

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

157

1.67

1.14

1.5

1.4

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

498

1.73

1.14

4.1

3.8

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.06

1.12

1.0

1.2

—

(3019225) pH of Specimen

2.13

1.10

4.7

4.6

—

(40768797) Stomach Pathology biopsy report

1.80

1.03

1.2

—

(3041096) Erythrocytes [Presence] in Urine by Automated

162

1.61

1.00

3.4

3.1

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

1.77

0.99

2.1

1.6

324.2

461.0

pmol/l

2.08

(4010399)

1.98

0.97

1.1

1.2

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.87

0.96

4.8

5.7

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.78

0.95

2.7

2.4

4.4

3.1

e6/l

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

138

1.61

0.94

2.0

—

(3042936) Bacteria identified in Isolate by Culture

1.91

0.93

2.8

2.4

—

(3023368) Bacteria identified in Blood by Culture

123

1.61

0.88

4.7

3.9

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

0.00

0.81

0.0

1.4

—

(3034274) Bile acid [Moles/volume] in Serum --fasting

0.00

0.80

0.0

2.3

—

3.3

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.79

0.0

1.1

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

144

1.53

0.79

2.0

1.9

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.25

0.78

1.4

2.6

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

1.69

0.77

4.1

4.2

21.0

22.2

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

2.16

0.76

1.0

1.4

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

1.64

0.75

2.7

2.2

0.7

e6/l

—

(3019060) Gas panel - Arterial blood

2.07

0.74

2.2

5.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

297

1.41

0.71

3.7

3.9

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.65

0.67

1.0

—

(3044640) Blood type and Crossmatch panel - Blood

188

1.41

0.62

2.2

2.1

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

162

1.41

0.58

1.7

1.3

0.6

2.2

u/ml

—

(3000492) Spirometry study

1.57

0.57

1.3

—

(40760892) CBC W Ordered Manual Differential panel - Blood

136

1.43

0.56

5.7

4.9

—

(3002256) Pathology report gross observation

1.49

0.55

1.2

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.55

0.54

1.5

1.7

—

(3027945) Reticulocytes/100 erythrocytes in Blood

1.61

0.50

2.7

3.4

1.7

1.8

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.57

0.50

1.6

1.4

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.57

0.50

3.1

3.0

—

(21494755) Public health laboratory ask at order entry panel

0.60

0.49

1.0

1.3

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

1.50

0.48

1.0

1.5

—

(40761536) Microorganisms panel - Urine sediment

1.47

0.47

6.6

3.3

—

(3007164) IgA [Mass/volume] in Serum or Plasma

151

1.35

0.44

1.5

1.3

2.1

2.4

g/l

0.31

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

0.00

0.41

0.0

1.3

—

(3006184) Hemoglobin [Mass/volume] in Capillary blood

0.00

0.41

0.0

2.2

—

122.0

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

189

0.74

0.41

1.9

1.8

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

115

0.66

0.40

1.6

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.40

0.0

1.1

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.40

0.0

1.1

—

(3019832) Treponema pallidum Ab [Presence] in Serum

164

0.75

0.35

1.5

1.7

—

(3002385) Erythrocyte distribution width [Ratio]

524

1.27

0.33

22.7

13.4

13.0

13.5

3.73

519

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

179

1.24

0.29

2.3

1.7

—

(4035726)

1.27

0.23

1.6

1.4

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.20

0.22

1.2

1.5

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.20

0.22

1.6

1.4

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

0.21

0.0

1.2

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.3

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(4094501)

0.00

0.21

0.0

1.1

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

118

1.23

0.21

1.4

1.3

1.1

5.9

u/ml

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.21

0.0

2.7

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.74

0.18

1.6

1.5

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.74

0.18

1.6

1.5

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.74

0.18

1.6

1.5

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.74

0.18

1.6

1.5

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.71

0.17

1.6

—

(3003694) ABO and Rh group [Type] in Blood

220

0.88

0.14

1.6

1.7

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

220

0.88

0.14

2.1

2.0

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.11

0.08

1.0

1.5

—

(3009542) Hematocrit [Volume Fraction] of Blood

577

1.11

0.07

18.2

11.4

40.4

40.3

0.17

467

(3050129) First trimester maternal screen panel - Serum or Plasma

0.86

0.07

1.4

1.5

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

104

0.85

0.07

1.2

1.5

—

(1761868) Lipid panel - Serum or Plasma

223

0.98

0.00

2.3

2.2

—

(3026493) Urate [Moles/volume] in Serum or Plasma

129

1.01

0.00

2.3

2.8

335.3

3336.2

umol/l

0.49

107

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.1

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.0

1.0

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.1

—

90.1

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.0

1.3

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.0

1.1

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

0.0

1.8

—

2.5

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

0.8

—

(3011985) Renin [Units/volume] in Plasma

0.00

0.0

1.1

—

31.7

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(40768441) Liver Pathology biopsy report

0.00

0.0

1.0

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

1.3

—

(3001405) CD3+CD8+ (T8 suppressor) cells [#/volume] in Blood

0.00

0.0

1.2

—

585.0

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.00

0.00

1.6

—

(36660697) Celiac disease serology panel - Serum

1.00

0.00

1.3

1.1

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.0

2.4

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(4062490)

0.00

0.0

1.6

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

2110.0

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

0.0

1.3

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

0.00

0.0

2.0

—

(3021901) Oxygen saturation in Capillary blood

0.00

0.0

3.1

—

(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma

0.00

0.0

3.0

—

7.0

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.92

0.00

1.6

1.5

—

(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

6.6

—

2542.7

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(36304052) Adalimumab Ab [Units/volume] in Serum or Plasma

0.00

0.0

2.0

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

2.5

—

164.8

—

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

0.00

0.0

1.4

—

(3028271) Lactate [Moles/volume] in Capillary blood

0.00

0.0

2.0

—

2.1

—

(3005033) Fetal Nuchal fold Thickness US

0.92

0.00

1.6

1.5

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3038026) Centromere Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.0

1.7

—

91.0

—

(3044927) Protein electrophoresis panel - Urine

0.00

0.0

1.3

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.5

—

(3025271) CD3-CD16+CD56+ (Natural killer) cells [#/volume] in Blood

0.00

0.0

1.2

—

0.2

—

(3036669) Protein S actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

1.3

—

105.4

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

0.0

1.3

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.89

0.00

1.6

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(3044941) Cell count panel - Synovial fluid

0.00

0.0

1.0

—

(3015076) Soybean IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(40768795) Lymph node Pathology biopsy report

0.00

0.0

1.0

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

2.0

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.0

1.2

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

Mortality – FinRegistry

↥

Association

Association between endpoint F5_NIGHTMARES and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have F5_NIGHTMARES.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: F5_NIGHTMARES – Nightmares

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Nightmares

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints