Sexual dysfunction

F5_SEXDYS

sexual dysfunction: ['Disturbances in sexual desire and the psychophysiologic changes that characterize the sexual response cycle and cause marked distress and interpersonal difficulty.']

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F52
  • Hospital discharge: ICD-9 3027
  • Cause of death: ICD-10 F52
  • Cause of death: ICD-9 3027

2 out of 7 registries used, show all original rules.

605

4. Check minimum number of events

None

605

5. Include endpoints

None

605

6. Filter based on genotype QC (FinnGen only)

580

Control definitions (FinnGen only)

Control exclude
F5_BEHAVE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F50-F59
Name in latin
Perturbationes sexuales non organicae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3670 859 2778
Only index persons 3531 836 2695
Unadjusted period prevalence (%)
Whole population 0.06 0.02 0.08
Only index persons 0.09 0.03 0.10
Median age at first event (years)
Whole population 40.63 32.07 43.31
Only index persons 40.15 31.85 42.72

-FinnGen-

Key figures

All Female Male
Number of individuals 580 169 411
Unadjusted period prevalence (%) 0.15 0.06 0.19
Median age at first event (years) 48.11 38.12 52.21

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
605
Matched controls
6050
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F52.2
ICD-10 Finland
Failure of genital response
66.7
307.7
261
68
F52.0
ICD-10 Finland
Lack or loss of sexual desire
283.2
116.3
115
5
F51.0
ICD-10 Finland
Nonorganic insomnia
+∞
113.2
105
*
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
7.9
83.6
130
202
N48.4
ICD-10 Finland
Impotence of organic origin
11.4
77.3
86
87
F52.9
ICD-10 Finland
Unspecified sexual dysfunction, not caused by organic disorder or disease
194.3
67.6
69
*
F52
ICD-10 Finland
Sexual dysfunction, not caused by organic disorder or disease
23.1
60.9
45
21
F52.6
ICD-10 Finland
Nonorganic dyspareunia
+∞
55.0
52
*
N06AX11
ATC
mirtazapine; oral
3.4
43.7
234
953
N05AH04
ATC
quetiapine; oral
3.4
34.4
150
529
N06AX12
ATC
bupropion; oral
4.6
34.0
90
223
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.7
31.9
117
367
N05BA04
ATC
oxazepam; oral
2.9
28.7
173
730
F52.8
ICD-10 Finland
Other sexual dysfunction, not caused by organic disorder or disease
105.1
27.9
30
*
F52.4
ICD-10 Finland
Premature ejaculation
146.5
26.8
28
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.7
26.6
93
281
N06AB06
ATC
sertraline; oral
3.4
24.8
99
326
N06AB05
ATC
paroxetine; oral
4.4
22.2
58
141
N05CF01
ATC
zopiclone; oral
2.5
22.0
180
871
N06AB04
ATC
citalopram; systemic
2.8
21.7
135
571
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
4.4
21.3
56
137
N06AX16
ATC
venlafaxine; oral
3.0
21.0
109
418
F52.3
ICD-10 Finland
Orgasmic dysfunction
206.5
19.7
20
*
N06AX21
ATC
duloxetine; oral
3.2
19.7
86
298
Z71.8
ICD-10 Finland
Other specified counselling
2.3
19.4
207
1118
F52.5
ICD-10 Finland
Nonorganic vaginismus
+∞
18.8
18
*
N03AX09
ATC
lamotrigine; oral
4.3
18.8
50
123
SPAT1240
SPAT
Therapeutic discussion
3.1
18.8
89
323
P06
ICPC
Sleep disturbance
3.2
18.7
82
284
N94.1
ICD-10 Finland
Dyspareunia
20.1
18.3
27
14
N05AX12
ATC
aripiprazole; systemic
4.1
18.2
53
140
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
4.5
18.2
46
109
E29.1
ICD-10 Finland
Testicular hypofunction
6.8
17.6
28
43
N05CD07
ATC
temazepam; oral
3.4
17.5
66
208
N06AX22
ATC
agomelatine; oral
7.6
17.5
25
34
P29
ICPC
Psychological sympt/compl other
3.5
17.5
64
198
N06AB10
ATC
escitalopram; oral
2.4
17.4
149
727
A06AC01
ATC
ispaghula (psylla seeds); oral
2.4
17.2
144
696
XKD00
NOMESCO Finland
Uroflowmetry
2.6
17.1
117
514
N05CF02
ATC
zolpidem; oral
2.7
16.8
106
448
Z3231
NOMESCO Finland
Registered nurse
2.2
16.5
175
933
N05AH03
ATC
olanzapine; systemic
3.4
16.4
62
196
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.2
16.2
70
240
N06AB03
ATC
fluoxetine; oral
2.9
16.1
81
303
N05AB03
ATC
perphenazine; systemic, rectal
4.7
15.8
37
82
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
4.3
15.7
42
104
Z76.0
ICD-10 Finland
Issue of repeat prescription
2.3
15.1
146
746
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
14.9
160
854
N05BA01
ATC
diazepam; systemic, rectal
2.7
14.7
84
336
G04BE01
ATC
alprostadil; parenteral, urethral
6.8
14.6
23
35
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
14.3
213
1282
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.3
14.1
56
182
N06AX26
ATC
vortioxetine; oral
3.2
14.1
60
204
N03AX16
ATC
[U] pregabalin
2.2
14.0
135
688
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.2
13.8
134
684
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.8
13.7
74
287
N03AE01
ATC
clonazepam; systemic
3.7
13.6
44
125
N03AG01
ATC
valproic acid; systemic, rectal
3.3
13.4
53
172
A04
ICPC
Weakness/tiredness general
2.6
13.3
88
378
F34.1
ICD-10 Finland
Dysthymia
4.2
13.3
36
90
N05AX08
ATC
risperidone; systemic
3.1
13.2
59
206
A02BC02
ATC
pantoprazole; systemic
1.9
13.2
385
2879
N06AX05
ATC
trazodone; oral
6.3
13.0
22
36
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.4
12.9
99
456
R53
ICD-10 Finland
Malaise and fatigue
2.1
12.8
137
726
H04.10
ICD-10 Finland
Dry eye syndrome
2.9
12.5
64
241
F50.9
ICD-10 Finland
Eating disorder, unspecified
132.6
12.5
13
*
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
4.8
12.2
28
61
F32
ICD-10 Finland
Depressive episode
3.4
12.1
44
135
N02AX02
ATC
tramadol; systemic, rectal
1.9
12.1
253
1684
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
2.0
12.1
161
922
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.8
12.0
65
252
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
11.7
159
917
Z3226
NOMESCO Finland
Physiotherapist
2.2
11.7
108
538
M54.5
ICD-10 Finland
Low back pain
1.9
11.6
215
1374
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
5.2
11.6
24
48
R06.5
ICD-10 Finland
Mouth breathing
2.5
11.5
80
352
P03
ICPC
Feeling depressed
2.6
11.5
70
289
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.7
11.4
65
259
Z2221
NOMESCO Finland
Medical doctor
2.0
11.4
164
963
M79.6
ICD-10 Finland
Pain in limb
1.8
11.4
228
1492
A06AD11
ATC
lactulose; oral
2.5
11.1
72
306
XKD06
NOMESCO Finland
Physiologic investigation of micturition
4.5
11.1
27
62
K59.09
ICD-10 Finland
Constipation, unspecified
3.4
10.9
40
124
N06BA04
ATC
methylphenidate; oral
3.5
10.6
36
106
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
10.6
204
1314
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.2
10.5
100
502
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.0
10.4
145
839
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.5
10.4
70
303
F41.1
ICD-10 Finland
Generalized anxiety disorder
3.1
10.4
44
149
UJF32
NOMESCO Finland
Coloscopy
2.0
10.3
139
795
S29
ICPC
Skin symptom/complaint other
2.1
10.3
104
535
Z01.7
ICD-10 Finland
Laboratory examination
2.2
10.2
91
446
R52.9
ICD-10 Finland
Pain, unspecified
2.5
10.2
67
287
R06.0
ICD-10 Finland
Dyspnoea
1.9
10.1
143
831
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.7
10.1
58
232
L17
ICPC
Foot/toe symptom/complaint
1.9
10.1
155
926
G47.3
ICD-10 Finland
Sleep apnoea
1.9
10.1
158
950
R4110
NOMESCO Finland
Physiotherapy
1.9
10.1
158
950
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
4.2
10.1
27
67
N06AA12
ATC
doxepin; systemic
3.7
9.9
31
86
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.3
9.8
83
398
L08
ICPC
Shoulder symptom/complaint
2.0
9.7
123
687
K02.1
ICD-10 Finland
Caries of dentine
1.7
9.7
376
2936
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
4.9
9.6
21
44
C07AB07
ATC
bisoprolol; oral
1.7
9.6
237
1633
N03AX12
ATC
[U] gabapentin; oral
2.1
9.5
95
486
SPAT1307
SPAT
Psychosocial counselling and guidance
2.9
9.4
45
163
R35
ICD-10 Finland
Polyuria
2.8
9.4
49
186
F90.0
ICD-10 Finland
Disturbance of activity and attention
3.2
9.4
38
125
S18
ICPC
Laceration/cut
1.7
9.4
250
1755
F31.8
ICD-10 Finland
Other bipolar affective disorders
4.6
9.4
22
49
N06AG02
ATC
moclobemide; oral
3.4
9.3
33
100
R13
ICD-10 Finland
Dysphagia
3.0
9.3
42
148
P76
ICPC
Depressive disorder
2.7
9.2
51
200
F33.1
ICD-10 Finland
Recurrent depressive disorder, current episode moderate
4.0
9.2
26
67
R42
ICD-10 Finland
Dizziness and giddiness
2.0
9.2
109
594
N05AA02
ATC
levomepromazine; systemic
3.6
9.2
30
86
D01
ICPC
Abdominal pain/cramps general
2.4
9.1
66
295
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
7.2
9.1
21
30
P01
ICPC
Feeling anxious/nervous/tense
2.2
9.0
78
376
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
4.3
9.0
23
55
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.5
9.0
57
240
UJD02
NOMESCO Finland
Gastroscopy
3.3
8.9
33
103
SPAT1254
SPAT
Administration of medicine
2.2
8.9
77
372
R01AD09
ATC
mometasone; nasal
1.7
8.8
265
1912
M54.4
ICD-10 Finland
Lumbago with sciatica
2.0
8.8
103
558
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
8.8
189
1245
SPAT1249
SPAT
Treatment-related counselling outside office
1.7
8.8
213
1452
SPAT1310
SPAT
Counselling related to known health issue
1.8
8.6
172
1108
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.7
8.5
283
2093
Z70.9
ICD-10 Finland
Sex counselling, unspecified
91.3
8.4
9
*
R03AC02
ATC
salbutamol; inhalant
1.7
8.4
307
2321
SFA10
NOMESCO Finland
One-surface restoration
1.7
8.4
333
2572
3027C
ICD-9 Finland
Sexual deviations and disorders, Psychosexual dysfunction[SEKSUAALINEN KIIHOTTUMISVAIKEUS]
+∞
8.3
8
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.3
8.3
31
97
F32.1
ICD-10 Finland
Moderate depressive episode
2.7
8.3
46
181
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.5
8.2
52
218
N05AD01
ATC
haloperidol; systemic
4.0
8.2
23
59
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
4.9
8.2
18
38
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
3.0
8.2
36
125
J02AC01
ATC
fluconazole; systemic
1.7
8.1
176
1157
M79.1
ICD-10 Finland
Myalgia
2.1
8.1
87
456
L03
ICPC
Low back symptom/complaint
1.8
8.1
150
943
R05
ICPC
Cough
1.8
8.1
129
775
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
3.2
8.1
31
99
N05BA12
ATC
alprazolam; oral
2.5
8.0
53
227
C07AA05
ATC
propranolol; systemic
1.9
8.0
116
675
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.0
8.0
96
524
R51.80
ICD-10 Finland
Headache
2.0
8.0
93
502
F60.9
ICD-10 Finland
Personality disorder, unspecified
7.4
8.0
18
25
A02BC03
ATC
lansoprazole; oral
1.8
8.0
140
866
N01
ICPC
Headache
2.2
8.0
70
340
N06AA09
ATC
amitriptyline; systemic
2.6
7.9
46
185
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.3
7.9
64
300
N06AA06
ATC
trimipramine; systemic
4.7
7.9
18
39
WZC00
NOMESCO Finland
Treatment plan or consultation
1.7
7.9
201
1379
SAA01
NOMESCO Finland
Simple examination of mouth
1.7
7.8
436
3644
N02BE01
ATC
paracetamol; systemic, rectal
1.9
7.8
507
4427
UKC02
NOMESCO Finland
Cystoscopy
2.0
7.7
85
450
N07BB01
ATC
disulfiram; oral
2.8
7.7
39
146
J01FF01
ATC
clindamycin; systemic
1.7
7.7
154
988
SPAT1243
SPAT
Psychiatric/psychological examination
3.7
7.6
24
67
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
7.6
236
1700
R00.2
ICD-10 Finland
Palpitations
2.6
7.6
46
189
N17
ICPC
Vertigo/dizziness
2.4
7.6
55
246
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.8
7.6
126
766
WX110
NOMESCO Finland
Infiltration anesthesia
1.7
7.6
424
3531
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.3
7.5
59
273
N04BC05
ATC
pramipexole; oral
2.7
7.5
40
154
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
4.3
7.5
19
45
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
7.3
7.5
17
24
R06AE07
ATC
cetirizine; oral
1.6
7.5
239
1734
M01AG02
ATC
tolfenamic acid; oral, rectal
2.1
7.5
76
391
N94.2
ICD-10 Finland
Vaginismus
81.1
7.4
8
*
L14
ICPC
Leg/thigh symptom/complaint
2.6
7.4
44
179
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
3.1
7.4
30
99
J05AB01
ATC
aciclovir; systemic
1.9
7.4
110
645
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
7.4
155
1007
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.3
7.4
60
282
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.1
7.4
75
386
L01
ICPC
Neck symptom/complaint
2.0
7.3
83
444
G47.0
ICD-10 Finland
Disorders of initiating and maintaining sleep [insomnias]
+∞
7.3
7
*
F50.2
ICD-10 Finland
Bulimia nervosa
+∞
7.3
7
*
H02AB07
ATC
prednisone; oral
2.1
7.3
69
345
L12
ICPC
Hand/finger symptom/complaint
2.0
7.2
86
468
ZXD20
NOMESCO Finland
Day surgery
2.1
7.1
70
355
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.5
7.1
45
189
A02BC01
ATC
omeprazole; systemic
1.8
7.1
131
820
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.7
7.1
38
147
XCK10
NOMESCO Finland
Photography of fundus of eye
2.3
7.1
53
241
R05
ICD-10 Finland
Cough
1.8
7.0
110
656
E0000UV, ,
ATC
1.6
6.9
219
1577
A99
ICPC
Disease/condition unspecnature/site
2.3
6.9
50
224
J20
ICD-10 Finland
Acute bronchitis
2.3
6.9
55
257
P74
ICPC
Anxiety disorder/anxiety state
3.0
6.8
30
104
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
6.2
6.8
17
28
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
6.8
176
1206
E000006, ,
ATC
2.8
6.8
34
127
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.3
6.8
51
232
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.8
6.7
105
624
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
2.6
6.7
39
157
M03BC51
ATC
orphenadrine, combinations; systemic
1.7
6.7
152
1006
M25.5
ICD-10 Finland
Pain in joint
1.6
6.7
171
1167
A02BA02
ATC
ranitidine; systemic
1.9
6.7
85
473
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
6.7
120
745
P01AB01
ATC
metronidazole; oral, rectal
1.6
6.7
199
1412
ZXA10
NOMESCO Finland
Bilateral
1.9
6.6
85
474
J01AA02
ATC
doxycycline; systemic
1.6
6.6
418
3518
F60.5
ICD-10 Finland
Anankastic personality disorder
7.9
6.6
14
18
Z01.2
ICD-10 Finland
Dental examination
1.6
6.6
254
1910
G04BE04
ATC
yohimbine; oral
12.4
6.6
11
9
G44.2
ICD-10 Finland
Tension-type headache
2.0
6.6
72
380
N02BF01
ATC
gabapentin; oral
2.4
6.6
44
190
ZY010
NOMESCO Finland
Hospital outpatient
2.6
6.6
38
153
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.1
6.6
66
338
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.2
6.5
53
249
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.2
6.5
25
80
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.8
6.5
103
615
N06AB08
ATC
fluvoxamine; oral
3.6
6.5
21
60
TLC00
NOMESCO Finland
Insertion of intrauterine device
2.8
6.5
31
113
A11
ICPC
Chest pain NOS
2.4
6.4
43
186
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.0
6.4
71
377
N05AB01
ATC
dixyrazine; systemic
8.3
6.4
13
16
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
6.1
6.3
16
27
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
6.3
91
527
G04CA02
ATC
tamsulosin; oral
1.7
6.3
140
919
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.0
6.3
75
408
N05AX15
ATC
cariprazine; oral
18.2
6.3
9
5
D19
ICPC
Teeth/gum symptom/complaint
1.6
6.3
165
1132
F50.8
ICD-10 Finland
Other eating disorders
+∞
6.3
6
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
6.3
98
583
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.0
6.2
65
337
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
3.7
6.2
19
52
E66.8
ICD-10 Finland
Other obesity
2.6
6.2
36
145
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
5.1
6.2
18
36
R39.1
ICD-10 Finland
Other difficulties with micturition
3.3
6.2
23
72
F51
ICD-10 Finland
Nonorganic sleep disorders
3.4
6.2
22
67
F41.09
ICD-10 Finland
UNS Panic Syndrome
3.4
6.2
22
67
U01
ICPC
Dysuria/painful urination
2.8
6.2
31
116
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
6.2
173
1205
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.5
6.2
317
2531
AA1AD
NOMESCO Finland
CT of head and brain
1.7
6.2
122
777
Y07
ICPC
Impotence NOS
10.2
6.1
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
190
625
3.97
50.21
3.3
2.1
14.19
13.56
nmol/l
0.45
182
576
112
273
4.81
43.64
2.3
1.7
36.29
38.47
nmol/l
0.56
112
264
78
187
4.64
30.62
1.7
1.3
5.50
7.69
u/l
1.33
66
159
444
3342
2.23
16.92
4.7
3.4
14.61
14.69
pmol/l
0.28
416
3069
384
2750
2.09
16.43
4.8
3.6
136.38
194.16
e6/l
—
8
37
515
4194
2.53
15.26
5.6
4.0
1.84
2.44
mu/l
0.82
483
3878
443
3436
2.08
14.11
9.2
7.9
76.14
77.58
u/l
0.27
417
3273
241
1540
1.94
13.43
2.1
1.8
99.24
93.85
pmol/l
1.06
129
846
428
3318
1.99
13.11
4.6
3.7
9.79
10.04
mm/h
0.16
411
3094
333
2403
1.86
12.41
7.5
6.4
0.20
0.19
e9/l
0.19
300
2142
280
1932
1.84
11.90
3.3
2.7
113.84
141.97
ug/l
1.40
266
1813
322
2320
1.83
11.86
7.4
6.1
0.58
0.58
e9/l
0.03
287
2038
322
2321
1.83
11.84
7.5
6.1
0.04
0.04
e9/l
0.06
289
2041
245
1630
1.85
11.65
2.8
2.2
74.43
72.65
nmol/l
0.47
225
1495
396
3053
1.86
11.57
4.3
3.7
—
—
—
0
0
328
2403
1.80
11.19
7.3
6.2
1.83
1.98
e9/l
1.47
299
2161
192
1200
1.88
11.01
2.9
2.1
320.08
274.85
u/l
0.17
177
1139
277
1941
1.79
10.90
8.8
7.8
1.20
1.21
mmol/l
0.46
250
1690
27
63
4.44
10.87
1.9
1.6
—
—
—
0
0
354
2683
1.77
10.46
11.5
9.6
3.84
4.08
e9/l
1.49
313
2359
157
938
1.91
10.24
3.8
3.0
—
—
—
0
0
158
966
1.86
9.51
2.2
2.0
2.69
2.89
mg/l
0.59
141
844
252
1768
1.73
9.51
8.3
6.9
1.20
1.21
mmol/l
0.37
233
1635
206
1367
1.77
9.45
3.6
2.8
57.37
62.75
u/l
0.70
193
1289
180
1151
1.80
9.35
3.8
2.9
0.22
0.49
e6/l
1.46
123
878
219
1483
1.75
9.34
4.5
3.4
64.77
110.21
e6/l
0.50
146
1053
240
1668
1.73
9.32
2.1
2.0
—
—
—
0
0
60
257
2.48
9.09
3.0
3.9
4.66
4.71
pmol/l
0.13
53
235
176
1128
1.79
9.02
3.9
2.8
—
—
—
0
0
194
1280
1.76
9.00
3.8
3.0
31.90
92.13
e6/l
0.61
136
994
100
535
2.04
8.87
1.3
1.2
—
—
—
0
0
297
2207
1.68
8.87
7.6
6.6
8.68
8.54
%
0.36
286
2097
302
2254
1.68
8.87
7.0
6.1
56.39
57.08
%
0.45
290
2148
154
955
1.82
8.78
1.6
1.4
2.35
2.44
g/l
0.32
97
635
547
4859
2.31
8.74
19.8
13.7
139.66
139.67
mmol/l
0.05
537
4736
50
200
2.64
8.72
1.7
1.4
13.96
22.58
iu/l
1.32
41
168
287
2121
1.67
8.70
7.3
6.4
0.72
0.66
%
0.99
276
2007
294
2191
1.67
8.59
7.3
6.3
3.03
2.88
%
0.58
281
2077
338
2617
1.66
8.47
6.2
5.1
6.81
6.70
mmol/l
0.34
322
2442
246
1756
1.68
8.45
3.5
2.8
5.75
5.75
ph
0.00
16
160
547
4878
2.27
8.33
20.3
13.8
3.98
3.98
mmol/l
0.04
538
4748
73
355
2.20
8.28
1.4
1.2
—
—
—
0
0
162
1038
1.77
8.21
1.4
1.2
3.21
1.06
u/ml
0.70
46
304
302
2284
1.64
8.20
7.4
6.3
28.72
28.06
%
0.45
289
2175
242
1731
1.66
8.18
5.6
5.7
36.43
36.28
g/l
0.15
221
1637
131
790
1.84
8.12
4.2
3.3
376.86
707.08
ng/l
0.57
93
578
301
2281
1.64
8.06
7.3
7.1
11.39
12.01
umol/l
0.32
283
2182
177
1169
1.73
8.04
2.2
1.9
—
—
—
0
0
546
4890
2.20
7.81
17.8
12.2
20.89
23.41
mg/l
1.13
442
3760
291
2202
1.62
7.73
7.1
6.4
—
—
—
0
0
151
967
1.75
7.60
1.9
1.7
0.61
1.15
mg/l
6.53
118
720
169
1121
1.70
7.48
6.3
4.6
7.40
7.40
ph
0.21
20
202
521
4607
1.94
7.44
5.1
4.0
6.07
5.94
mmol/l
0.88
484
4270
163
1073
1.71
7.41
7.1
7.2
—
—
—
0
0
102
585
1.89
7.35
3.5
2.5
2.27
2.34
g/l
0.69
94
549
114
680
1.83
7.26
3.4
2.7
0.83
1.30
e6/l
0.99
51
385
284
2159
1.59
7.25
3.9
3.0
0.00
0.01
estimate
0.50
33
386
137
864
1.76
7.24
1.8
1.5
20.10
19.75
nmol/l
0.12
127
745
114
682
1.83
7.19
1.4
1.2
13.02
7.59
u/ml
0.45
52
278
494
4315
1.79
7.09
6.7
5.1
40.04
39.54
mmol/mol
0.44
473
4070
121
741
1.79
7.06
1.5
1.2
17.63
26.41
iu/ml
0.96
27
232
44
190
2.42
6.57
3.1
2.6
1122.56
2473.90
u/l
—
10
80
278
2137
1.56
6.56
5.0
4.1
0.00
0.00
estimate
-0.00
34
421
133
855
1.71
6.51
3.0
2.4
3.19
5.38
e6/l
1.05
117
765
423
3580
1.60
6.48
4.3
3.1
42.91
48.65
u/l
0.96
397
3411
279
2152
1.55
6.45
3.9
3.0
0.00
0.00
estimate
0.50
35
439
93
544
1.84
6.27
3.7
2.6
24.30
24.48
%
0.05
86
475
112
693
1.76
6.27
2.9
4.0
0.83
0.82
mmol/l
0.27
101
662
75
409
1.95
6.26
2.2
1.9
380.52
364.77
nmol/l
0.28
69
384
220
1622
1.56
6.15
3.8
3.8
33.95
33.59
u/l
0.04
209
1548
101
612
1.78
6.06
1.8
2.5
106.24
121.49
ug/g
0.24
79
505
218
1609
1.55
6.04
4.1
3.2
19.27
39.11
ng/l
4.16
127
1024
161
1109
1.62
5.99
4.3
4.0
90.59
90.71
%
0.02
154
1090
88
515
1.83
5.92
2.1
1.7
—
—
—
0
0
54
267
2.12
5.89
3.8
2.0
—
—
—
0
0
250
1912
1.52
5.85
13.6
12.0
1.13
1.23
inr
1.14
59
582
179
1274
1.58
5.78
3.3
3.6
2.35
2.35
mmol/l
0.10
158
1155
30
115
2.69
5.73
5.7
2.5
—
—
—
0
0
90
542
1.78
5.50
9.1
7.0
1.06
1.02
mmol/l
0.94
84
517
140
951
1.61
5.47
3.2
2.6
—
—
—
0
0
147
1015
1.59
5.35
2.7
3.2
685.17
1169.50
ng/l
2.33
122
861
29
114
2.62
5.29
1.3
1.3
—
—
—
0
0
140
960
1.60
5.24
4.0
3.1
1.01
1.02
kg/l
0.85
13
133
45
218
2.15
5.18
4.2
1.9
—
—
—
0
0
48
241
2.08
5.05
5.8
4.5
107.73
86.41
ng/l
0.68
41
223
188
1391
1.51
4.98
4.4
3.3
8.44
8.68
mmol/l
0.25
165
1195
89
550
1.72
4.97
1.6
1.5
—
—
—
0
0
278
2226
1.46
4.94
4.4
4.2
2.43
2.23
ug/l
0.09
255
2016
123
832
1.60
4.85
3.1
2.7
536.53
586.76
mosm/kgh2o
1.56
100
720
54
288
1.96
4.82
3.8
1.9
—
—
—
0
0
54
290
1.95
4.73
3.8
1.9
—
—
—
0
0
54
292
1.93
4.64
3.8
1.9
—
—
—
0
0
105
692
1.63
4.59
2.0
1.6
—
—
—
0
0
53
287
1.93
4.54
1.7
1.8
—
—
—
0
0
372
3181
1.44
4.47
4.2
3.4
—
—
—
0
0
534
4928
1.71
4.40
5.4
4.3
2.77
2.84
mmol/l
0.92
508
4640
95
617
1.64
4.40
1.6
1.3
235.00
453.33
titre
2.24
16
117
28
120
2.40
4.31
2.8
3.5
—
—
—
0
0
69
421
1.72
4.04
3.5
2.8
1.70
1.71
%
0.01
63
384
27
118
2.35
4.00
1.2
1.2
—
—
—
0
0
559
5254
1.84
3.93
13.2
9.5
28.59
30.64
u/l
1.87
547
5106
18
65
2.82
3.88
1.7
1.5
149.14
180.39
pmol/l
0.39
18
65
96
649
1.57
3.76
2.5
2.1
—
—
—
0
0
56
329
1.77
3.74
3.9
3.2
—
—
—
0
0
161
1215
1.44
3.71
3.7
3.5
400.80
223.07
mg/l
0.21
122
842
21
86
2.49
3.58
1.0
1.1
2.19
4.22
u/ml
—
10
46
92
623
1.56
3.58
1.9
1.6
1272.99
1144.00
nmol/l
0.33
74
495
150
1126
1.44
3.55
5.6
4.5
—
—
—
0
0
12
31
3.93
3.50
2.4
1.4
—
—
—
0
0
163
2074
0.71
3.49
3.1
2.5
—
—
—
0
0
523
4860
1.56
3.49
4.9
4.0
1.34
1.37
mmol/l
0.99
498
4590
248
2038
1.37
3.44
12.4
9.1
0.00
0.00
e9/l
0.62
204
1675
524
4880
1.55
3.36
5.0
4.0
4.57
4.66
mmol/l
1.40
499
4623
60
373
1.68
3.30
4.5
4.4
—
—
—
0
0
155
1190
1.41
3.21
2.4
2.6
360.20
5966.95
umol/l
3.78
135
1075
7
11
6.42
3.19
1.1
1.1
—
—
—
0
0
149
1140
1.41
3.14
4.7
3.1
0.00
0.01
estimate
0.69
33
399
138
1047
1.41
3.04
2.6
2.3
—
—
—
0
0
168
1318
1.38
3.04
2.6
2.8
0.68
0.74
ug/l
0.36
105
765
27
134
2.06
3.00
1.3
1.3
—
—
—
0
0
42
243
1.78
2.99
1.1
1.1
—
—
—
0
0
10
26
3.89
2.99
5.7
3.2
43160.00
43273.08
ug/l
—
10
26
5
5
10.07
2.98
1.0
1.0
—
—
—
0
0
5
5
10.07
2.98
1.0
1.0
—
—
—
0
0
5
5
10.07
2.98
1.0
1.0
—
—
—
0
0
19
82
2.36
2.94
1.0
1.1
0.37
0.86
u/ml
—
10
34
32
171
1.92
2.91
1.2
1.2
—
—
—
0
0
50
307
1.69
2.90
2.1
2.9
66.56
71.14
e9/l
0.29
31
238
253
2126
1.33
2.90
2.7
2.6
—
—
—
0
0
31
165
1.93
2.86
1.6
2.2
1.46
1.46
g/l
0.00
26
146
17
71
2.43
2.82
3.5
2.2
—
—
—
0
0
63
414
1.58
2.81
2.7
2.6
39.18
145.01
u/l
0.46
55
364
58
374
1.61
2.79
5.1
3.3
1.79
1.84
mmol/l
0.04
51
304
58
374
1.61
2.79
4.9
3.3
5.85
5.81
kpa
0.10
53
365
56
358
1.62
2.79
13.6
10.2
—
—
—
0
0
123
929
1.41
2.77
1.8
1.7
—
—
—
0
0
89
634
1.47
2.74
3.3
3.3
2.42
2.43
mmol/l
0.62
77
560
35
197
1.82
2.74
9.6
2.5
—
—
—
0
0
6
10
6.05
2.70
1.3
1.1
—
—
—
0
0
583
5627
1.99
2.66
26.2
17.5
246.08
246.44
e9/l
0.05
571
5504
12
43
2.83
2.66
4.8
1.2
281.00
290.77
mosm/kgh2o
—
7
31
7
15
4.71
2.60
1.0
1.1
—
—
—
0
0
19
87
2.22
2.60
1.1
1.1
—
—
—
0
0
69
472
1.52
2.59
9.7
10.3
0.86
0.99
mmol/l
0.11
52
376
503
4707
1.41
2.55
4.5
3.6
1.37
1.35
mmol/l
0.18
470
4429
154
1224
1.35
2.53
1.7
1.7
1.41
1.47
mmol/l
0.25
134
1051
583
5635
1.95
2.52
26.3
17.4
4.64
4.66
e12/l
0.39
572
5506
548
5215
1.54
2.50
15.0
11.3
—
—
—
0
0
25
130
1.96
2.49
4.2
3.2
1.55
1.45
mg/l
0.22
25
122
583
5637
1.94
2.48
26.3
17.5
6.69
6.71
e9/l
0.08
572
5505
20
96
2.12
2.45
1.0
1.1
0.22
2.44
u/ml
—
9
51
50
325
1.59
2.36
2.3
2.3
—
15.42
—
0
26
71
499
1.48
2.35
1.4
1.4
—
—
—
0
0
159
1286
1.32
2.30
4.6
4.1
10.24
11.22
mg/mmol
0.11
116
871
12
47
2.58
2.28
1.2
1.2
—
—
—
0
0
104
792
1.38
2.23
1.8
1.6
495.70
32184325.34
pmol/l
0.96
90
696
581
5627
1.82
2.22
26.6
17.6
41.33
41.46
%
0.20
561
5305
10
35
2.89
2.21
2.6
3.4
37.93
22.18
mu/l
—
10
35
65
455
1.48
2.21
1.4
1.6
—
—
—
0
0
29
166
1.78
2.19
2.6
2.7
—
—
—
0
0
19
95
2.03
2.12
1.1
1.1
—
—
—
0
0
11
43
2.59
2.09
1.3
1.3
—
—
—
0
0
44
287
1.57
2.07
3.3
3.0
5.19
5.14
kpa
0.16
44
275
6
15
4.03
2.04
2.8
1.7
—
—
—
0
0
29
171
1.73
2.00
2.3
2.2
—
—
—
0
0
167
1386
1.28
1.97
2.8
2.3
—
—
—
0
0
27
157
1.75
1.96
1.7
1.7
—
—
—
0
0
5
139
0.35
1.90
1.6
1.5
—
—
—
0
0
7
22
3.21
1.88
2.4
2.1
145.43
134.82
nmol/l
—
7
17
32
198
1.65
1.87
1.5
1.4
—
9.77
—
0
9
8
28
2.88
1.86
1.1
1.0
—
—
—
0
0
11
46
2.42
1.86
1.5
1.5
—
—
—
0
0
72
533
1.40
1.84
3.0
3.1
7.81
9.34
umol/l
0.21
62
471
40
263
1.56
1.84
3.0
6.8
—
—
—
0
0
8
29
2.78
1.79
1.1
1.0
—
—
—
0
0
5
136
0.36
1.77
1.6
1.5
—
—
—
0
0
5
137
0.36
1.77
1.6
1.5
—
—
—
0
0
9
36
2.52
1.74
1.0
1.2
—
—
—
0
0
22
125
1.79
1.74
1.5
1.4
—
—
—
0
0
7
24
2.94
1.72
1.1
1.3
190.71
150.33
nmol/l
—
7
24
50
352
1.46
1.69
5.2
4.6
0.00
0.15
%
3.54
19
116
45
311
1.48
1.67
3.8
2.6
4.68
4.68
kpa
0.00
40
301
17
90
1.91
1.66
3.0
2.7
—
—
—
0
0
49
345
1.46
1.66
4.2
4.3
0.40
0.49
%
0.21
20
119
37
247
1.53
1.62
1.1
1.2
—
—
—
0
0
38
256
1.52
1.60
5.2
9.3
23.54
24.47
mmol/l
0.59
38
241
10
43
2.35
1.59
1.1
1.2
1.28
1.41
nmol/l
—
10
38
7
26
2.71
1.58
1.3
1.1
—
—
—
0
0
7
26
2.71
1.58
2.0
2.4
564.86
844.96
u/ml
—
7
26
11
50
2.22
1.57
1.6
1.7
—
—
—
0
0
38
257
1.51
1.57
14.4
12.8
94.87
94.40
%
0.29
38
257
25
153
1.66
1.55
5.5
5.0
—
—
—
0
0
28
428
0.64
1.54
1.4
1.4
—
—
—
0
0
8
33
2.44
1.54
1.1
1.0
—
—
—
0
0
37
250
1.51
1.54
1.3
1.2
—
—
—
0
0
53
385
1.41
1.53
3.2
2.4
11.08
10.46
g/l
0.31
53
351
17
93
1.85
1.53
1.4
1.4
—
—
—
0
0
24
147
1.66
1.49
1.4
1.2
—
—
—
0
0
9
38
2.39
1.46
1.4
1.6
31.26
34.14
g/l
—
9
31
5
16
3.14
1.44
1.8
1.6
20.56
18.84
umol/l
—
5
16
6
22
2.74
1.43
1.8
1.5
—
—
—
0
0
9
40
2.27
1.40
1.0
1.1
—
—
—
0
0
46
332
1.42
1.40
5.5
4.6
0.00
0.13
%
0.83
15
95
54
401
1.38
1.39
10.4
11.5
123.59
123.51
g/l
0.01
54
390
27
174
1.58
1.39
2.0
1.5
—
—
—
0
0
6
23
2.62
1.37
5.7
4.0
—
—
—
0
0
51
377
1.39
1.36
5.2
4.4
0.70
0.98
%
0.42
20
142
9
43
2.11
1.30
8.2
6.7
—
—
—
0
0
9
43
2.11
1.30
4.2
3.4
—
—
—
0
0
68
530
1.32
1.30
1.6
1.4
—
—
—
0
0
8
35
2.30
1.27
1.1
1.9
—
—
—
0
0
19
115
1.67
1.26
1.7
1.4
123.40
99.08
u/ml
—
5
24
66
518
1.31
1.21
1.2
1.3
—
—
—
0
0
33
231
1.45
1.20
2.3
2.8
—
—
—
0
0
14
79
1.79
1.17
1.2
1.1
—
15.38
—
0
6
0
35
0.00
1.15
0.0
3.9
—
43.54
—
0
35
7
31
2.27
1.10
1.0
1.1
—
—
—
0
0
5
21
2.39
1.09
1.2
1.1
142.30
183.46
mmol/24h
—
5
21
7
33
2.13
1.06
1.6
1.4
—
—
—
0
0
12
67
1.81
1.05
1.0
1.1
7.17
1.65
u/ml
—
6
30
29
204
1.44
1.05
2.9
3.3
—
—
—
0
0
11
60
1.85
1.03
2.8
3.6
—
—
—
0
0
7
34
2.07
1.03
1.0
1.0
—
—
—
0
0
14
83
1.70
1.02
3.2
1.9
—
—
—
0
0
9
48
1.89
1.00
1.0
1.5
—
—
—
0
0
5
23
2.18
0.98
2.4
6.1
—
7.43
—
0
7
0
29
0.00
0.98
0.0
1.0
—
222.04
—
0
29
7
36
1.96
0.97
3.1
2.3
—
—
—
0
0
12
69
1.75
0.97
1.2
1.1
—
—
—
0
0
13
77
1.70
0.96
1.0
1.1
1.33
1.46
g/l
0.66
13
67
12
197
0.60
0.95
1.2
1.6
—
—
—
0
0
34
252
1.37
0.94
3.4
2.4
—
—
—
0
0
14
86
1.64
0.91
1.0
1.1
2.11
1.36
u/ml
—
9
45
24
168
1.45
0.91
1.2
1.2
0.18
2.54
u/ml
—
5
11
35
263
1.35
0.90
1.7
1.5
—
—
—
0
0
131
1151
1.18
0.88
3.9
3.5
—
—
—
0
0
8
43
1.87
0.87
1.5
1.5
—
—
—
0
0
8
43
1.87
0.87
1.5
1.3
0.40
0.34
g/l
—
8
27
8
43
1.87
0.87
1.5
1.3
6.75
6.89
g/l
—
8
28
8
44
1.83
0.86
2.0
4.4
—
—
—
0
0
20
138
1.46
0.82
1.1
1.1
—
—
—
0
0
32
241
1.35
0.82
11.3
13.9
—
—
—
0
0
22
155
1.44
0.82
8.5
9.2
—
—
—
0
0
8
48
1.68
0.79
4.3
3.4
51.50
57.19
%
—
8
43
25
185
1.37
0.73
3.1
3.5
24.82
24.60
mmol/l
0.22
25
176
5
25
2.01
0.73
1.0
1.3
—
—
—
0
0
5
25
2.01
0.73
2.6
4.4
—
—
—
0
0
27
204
1.34
0.70
1.6
1.2
—
—
—
0
0
12
77
1.57
0.69
1.0
1.0
1.95
2.45
u/ml
—
7
41
7
42
1.67
0.68
2.4
2.3
33.29
34.14
pg
—
7
42
27
205
1.33
0.68
1.1
1.1
—
—
—
0
0
37
295
1.27
0.67
1.3
1.5
—
—
—
0
0
10
62
1.62
0.65
2.3
1.6
—
—
—
0
0
19
138
1.39
0.63
1.4
1.1
—
—
—
0
0
8
50
1.61
0.61
1.0
1.4
—
—
nmol/l
—
0
0
12
80
1.51
0.60
1.6
1.1
5.17
3.51
u/ml
—
6
35
0
22
0.00
0.59
0.0
1.1
—
3.12
—
0
6
8
55
1.46
0.56
1.8
2.3
1.07
1.14
e9/l
—
8
50
38
312
1.23
0.56
1.2
1.2
26.28
175.57
iu/ml
—
8
116
10
65
1.55
0.55
4.1
3.5
1.50
0.76
%
—
10
60
22
168
1.32
0.55
1.8
2.1
0.54
1.54
ug/l
1.04
22
154
6
39
1.54
0.53
1.5
1.4
—
—
—
0
0
21
163
1.30
0.49
2.7
4.1
0.20
0.22
g/l
—
10
86
12
85
1.42
0.47
8.2
3.5
—
—
—
0
0
5
82
0.61
0.46
5.2
2.9
51.80
56.83
%
—
5
82
29
348
0.82
0.42
1.7
1.4
—
—
—
0
0
32
378
0.84
0.40
6.1
3.1
—
—
—
0
0
7
104
0.67
0.39
4.0
3.6
—
—
—
0
0
10
71
1.42
0.39
1.3
1.3
—
—
—
0
0
5
35
1.43
0.39
1.4
1.7
14.80
12.77
umol/l
—
5
35
157
1473
1.09
0.39
1.5
1.5
—
—
—
0
0
34
289
1.19
0.39
2.4
2.9
145.47
148.58
ng/l
0.02
29
260
9
68
1.33
0.37
1.3
1.5
—
—
—
0
0
33
281
1.18
0.37
8.2
5.0
1.21
1.23
mmol/l
0.98
27
254
5
37
1.35
0.37
2.0
4.6
—
—
—
0
0
5
37
1.35
0.37
1.2
1.2
—
—
—
0
0
5
79
0.63
0.35
5.2
2.7
3.21
4.28
e9/l
—
5
79
9
122
0.73
0.35
1.0
1.2
—
—
—
0
0
6
43
1.40
0.35
1.8
2.4
465.00
458.51
e6/l
—
6
37
21
172
1.23
0.34
2.4
2.1
21.94
21.75
s
0.07
16
151
6
44
1.37
0.34
2.5
1.9
—
—
—
0
0
7
53
1.32
0.31
3.0
2.0
—
—
—
0
0
22
185
1.20
0.29
1.5
1.4
160.72
212.24
miu/ml
—
10
86
7
57
1.23
0.29
1.3
1.3
—
—
—
0
0
10
76
1.32
0.28
1.3
1.1
—
—
—
0
0
10
76
1.32
0.28
2.6
2.6
—
—
—
0
0
12
94
1.28
0.28
1.3
3.8
—
—
—
0
0
9
72
1.25
0.25
1.4
1.1
—
—
—
0
0
18
151
1.20
0.25
2.2
1.5
1.15
1.17
g/l
0.13
18
143
17
142
1.20
0.25
2.2
1.5
0.23
0.24
g/l
0.43
17
135
9
77
1.17
0.24
2.6
1.5
—
—
—
0
0
69
640
1.09
0.24
2.0
1.7
—
—
—
0
0
37
332
1.12
0.24
3.0
3.2
4.05
7.46
e9/l
1.06
32
288
5
40
1.25
0.22
1.2
1.2
—
—
—
0
0
5
40
1.25
0.22
1.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
6.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
3.2
—
5628.36
—
0
14
0
14
0.00
0.20
0.0
1.4
—
82.64
—
0
14
0
14
0.00
0.20
0.0
3.4
—
—
—
0
0
6
49
1.23
0.20
1.0
1.0
293.33
291.77
mg/l
—
6
43
6
49
1.23
0.20
2.0
2.7
—
—
—
0
0
7
63
1.11
0.17
1.1
1.3
—
—
—
0
0
5
67
0.74
0.17
1.6
2.5
—
—
—
0
0
35
381
0.91
0.17
3.7
5.2
3.01
43.27
ug/l
1.16
27
314
23
209
1.10
0.13
4.1
2.3
1.21
1.39
%
0.27
23
209
20
181
1.11
0.12
3.9
7.7
2.19
1.68
%
0.76
20
169
22
202
1.09
0.10
4.1
2.2
0.55
0.65
%
1.19
22
202
20
183
1.10
0.10
3.0
3.0
—
—
—
0
0
5
46
1.09
0.09
1.0
1.1
41.42
48.95
mg/l
—
5
39
6
56
1.07
0.08
1.7
1.1
—
—
—
0
0
7
68
1.03
0.08
1.0
1.1
—
—
—
0
0
8
75
1.07
0.07
11.1
3.9
—
—
—
0
0
8
77
1.04
0.07
1.1
1.8
—
—
—
0
0
59
571
1.04
0.07
1.5
1.7
—
—
—
0
0
74
722
1.03
0.05
1.3
1.3
—
—
—
0
0
19
178
1.07
0.05
4.1
7.8
0.91
0.88
%
0.11
19
167
12
110
1.09
0.05
1.1
1.1
—
—
—
0
0
12
111
1.08
0.04
1.1
1.1
—
—
—
0
0
11
102
1.08
0.03
1.2
1.3
—
—
—
0
0
127
1258
1.01
0.02
3.5
2.6
—
—
—
0
0
67
663
1.01
0.01
1.3
1.4
—
—
—
0
0
11
106
1.04
0.00
3.8
11.0
105.73
105.71
mmol/l
0.00
11
96
11
106
1.04
0.00
3.8
11.0
14.27
11.49
mmol/l
0.76
11
96
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
4.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
8.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
193.20
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
1.37
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
89
0.90
-0.00
1.8
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.4
—
0.33
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
42.20
—
0
5

Mortality – FinRegistry

Association

Association between endpoint F5_SEXDYS and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
F5_SEXDYS 1.439 [1.19, 1.75] < 0.001
Birth year 0.988 [0.98, 1.0] 0.026

During the follow-up period (1.1.1998 — 31.12.2019), 176 out of 1694 males with F5_SEXDYS died.

Mortality risk

Mortality risk for people of age

years, who have F5_SEXDYS.

N-year risk Females Males
1 No data 0.287%
5 No data 1.854%
10 No data 4.492%
15 No data 8.385%
20 No data 14.164%

Relationships between endpoints

Index endpoint: F5_SEXDYS – Sexual dysfunction

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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