No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1509 |
4. Check minimum number of eventsNone |
1509 |
5. Include endpointsNone |
1509 |
6. Filter based on genotype QC (FinnGen only) |
1509 |
Control definitions (FinnGen only)
- Control exclude
- I9_PULMHEART
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF3
- Parent code in ICD-10
- I26-I28
- Name in latin
- Aliae morbi cordis pulmonales
Similar endpoints
↥List of similar endpoints to
Secondary right heart disease
based on the number of shared cases.
Similar with more cases:
- Other pulmonary heart/vessel disease
- Pulmonary heart disease, diseases of pulmonary circulation
- Cardiovascular diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 13969 | 6378 | 7264 |
| Only index persons | 7983 | 4349 | 3634 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.20 | 0.18 | 0.20 |
| Only index persons | 0.15 | 0.16 | 0.14 |
| Median age at first event (years) | |||
| Whole population | 70.65 | 71.85 | 69.68 |
| Only index persons | 72.86 | 74.08 | 71.39 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1509 | 694 | 815 |
| Unadjusted period prevalence (%) | 0.30 | 0.24 | 0.36 |
| Median age at first event (years) | 70.57 | 69.13 | 71.79 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1341
- Matched controls
- 13410
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
8750.5
323.0
547
*
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
+∞
323.0
543
*
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
65.3
318.9
367
77
I27.0
ICD-10 Finland
Primary pulmonary hypertension
3249.0
294.8
274
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
440.8
285.9
277
8
I27.8
ICD-10 Finland
Other specified pulmonary heart diseases
+∞
281.4
260
*
C03CA01
ATC
furosemide; systemic
8.1
261.0
1013
3692
I50.9
ICD-10 Finland
Heart failure, unspecified
7.4
220.0
672
1609
C03DA01
ATC
spironolactone; oral
8.0
196.4
522
985
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
11.8
183.5
367
416
B01AA03
ATC
warfarin; systemic
5.7
181.6
727
2307
J96.1
ICD-10 Finland
Chronic respiratory failure
24.1
177.5
259
132
I26.0
ICD-10 Finland
Pulmonary embolism with mention of acute cor pulmonale
970.1
177.4
170
*
R06.0
ICD-10 Finland
Dyspnoea
5.5
174.1
706
2242
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
5.7
160.7
587
1611
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
5.3
153.2
617
1870
G04BE03
ATC
sildenafil; oral
33.7
149.3
197
68
I50.0
ICD-10 Finland
Congestive heart failure
6.9
144.6
415
819
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
5.6
125.9
435
1061
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.6
107.8
850
4326
C02KX04
ATC
macitentan; oral
+∞
94.9
90
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
3.6
94.4
565
2230
R03BB04
ATC
tiotropium bromide; inhalant
4.9
92.5
348
892
R03AC02
ATC
salbutamol; inhalant
3.2
87.1
839
4625
C01AA05
ATC
digoxin; systemic
4.4
86.1
362
1031
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
18.1
85.6
136
83
I48
ICD-10 Finland
Atrial fibrillation and flutter
3.3
85.6
623
2803
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
7.9
84.0
205
300
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
16.6
83.5
137
91
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
6.7
82.6
228
398
H02AB06
ATC
prednisolone; systemic
3.0
81.1
813
4510
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.9
79.8
399
1320
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
8.0
69.2
165
230
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.0
69.1
575
2718
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
3.3
67.5
428
1673
C07AB07
ATC
bisoprolol; oral
2.7
66.2
868
5379
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
5.8
64.0
196
385
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
8.8
63.4
142
178
R03AK06
ATC
salmeterol and fluticasone; inhalant
3.6
62.8
334
1131
XG466
NOMESCO Finland
Sleep oxymetry
8.9
62.6
139
172
GD2SN
NOMESCO Finland
Lung ventilation SPECT
36.9
62.4
80
23
C02KX05
ATC
riociguat; oral
+∞
59.8
57
*
WX740
NOMESCO Finland
Nitrogen oxide therapy
110.1
58.3
63
6
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
6.0
57.3
169
315
K93
ICPC
Pulmonary embolism
47.6
56.0
68
15
201
Kela drug reimbursment
Chronic cardiac insufficiency
4.5
54.4
212
538
XF622
NOMESCO Finland
Measurement of minute volume of heart
51.6
53.5
64
13
I26
ICD-10 Finland
Pulmonary embolism
+∞
53.5
51
*
207
Kela drug reimbursment
Chronic arrhythmias
3.0
53.2
381
1576
GD1UN
NOMESCO Finland
Lung circulation SPECT
34.6
53.1
69
21
UGC12
NOMESCO Finland
Flexible bronchoscopy
4.0
52.1
231
661
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
85.0
51.3
57
7
AP2
HP
Catheterization of the right side of the heart
31.1
51.1
68
23
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
5.0
50.0
174
391
C02KX01
ATC
bosentan; oral
505.8
49.7
49
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
3.7
49.2
239
738
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
5.0
48.7
167
369
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
14.4
48.4
83
61
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
15.9
47.3
78
52
I27.1
ICD-10 Finland
Kyphoscoliotic heart disease
+∞
47.2
45
*
R02
ICPC
Shortness of breath/dyspnoea
3.3
45.5
257
889
R03DA04
ATC
theophylline; systemic, rectal
4.1
45.5
194
532
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
8.5
44.0
99
124
4168X
ICD-9 Finland
Chronic pulmonary heart disease, Other chronic pulmonary heart diseases
+∞
44.0
42
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.1
43.6
276
1033
I50.1
ICD-10 Finland
Left ventricular failure
4.2
41.9
174
464
M04AA01
ATC
allopurinol; systemic
2.9
41.9
307
1261
FBB20
NOMESCO Finland
Thrombendarterectomy of pulmonary artery in chronic obstruction
+∞
41.9
40
*
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
8.1
41.0
95
125
R4110
NOMESCO Finland
Physiotherapy
2.4
40.3
435
2221
I50
ICD-10 Finland
Heart failure
5.3
40.3
130
267
GD1AD
NOMESCO Finland
Thorax CT examination
5.6
40.1
123
238
XG410
NOMESCO Finland
Flow-volume spirometry
5.3
39.0
125
255
R5140
NOMESCO Finland
Monitoring the use of the aid
3.5
38.9
204
662
WX725
NOMESCO Finland
Noninvasive ventilation
5.6
38.2
117
226
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
6.8
38.0
99
155
WX872
NOMESCO Finland
Intensive care
4.6
37.7
139
329
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.3
37.4
483
2675
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.5
37.3
344
1608
TGC00
NOMESCO Finland
Bronchial lavation
7.2
36.8
92
136
WX892
NOMESCO Finland
Monitored bed care
3.7
36.5
173
516
J45.9
ICD-10 Finland
Asthma, unspecified
2.6
36.4
312
1394
TFP20
NOMESCO Finland
Cardiodefibrillation
3.4
36.0
191
623
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.1
36.0
219
788
AN1
HP
Coronary angiography
2.7
35.7
280
1189
B01AB05
ATC
enoxaparin; parenteral
2.2
35.2
476
2675
XF620
NOMESCO Finland
Examination of circulation with color method
68.5
35.1
40
6
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
3.4
33.7
179
583
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.1
33.7
207
748
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.0
33.2
214
800
L04AA06
ATC
mycophenolic acid; systemic
10.1
31.8
64
66
Z94.2
ICD-10 Finland
Lung transplant status
169.0
31.8
33
*
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.4
30.1
160
520
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
30.0
321
1592
FB1BC
NOMESCO Finland
Extensive angiography of arteria pulmonalis
84.6
29.9
33
*
205
Kela drug reimbursment
Chronic hypertension
2.0
29.5
541
3392
J01MA12
ATC
levofloxacin; systemic
2.3
29.2
323
1628
TPH07
NOMESCO Finland
Cathetrisation of artery
2.9
29.1
199
769
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
105.7
28.8
31
*
K78
ICPC
Atrial fibrillation/flutter
2.9
28.3
190
723
C02KX02
ATC
ambrisentan; oral
+∞
28.2
27
*
R28
ICPC
Limited function/disability (R)
9.3
28.1
59
66
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.6
28.0
100
229
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
8.4
27.8
62
77
GDG10
NOMESCO Finland
Bilateral transplantation of lung
148.0
27.7
29
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.7
27.3
128
376
B01AF02
ATC
apixaban; oral
2.7
27.1
204
833
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
12.7
26.9
48
39
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.3
26.9
283
1386
R03BB01
ATC
ipratropium bromide; inhalant
3.6
26.4
127
381
R03BA01
ATC
beclometasone; inhalant
2.5
26.4
234
1049
G47.3
ICD-10 Finland
Sleep apnoea
2.3
26.3
284
1406
4169X
ICD-9 Finland
Chronic pulmonary heart disease, unspecified
+∞
26.1
25
*
PH7FT
NOMESCO Finland
Inmplantation of filter to inferior vena cava with radiological guidance
+∞
26.1
25
*
FB1AC
NOMESCO Finland
Angiography of arteria pulmonalis
265.4
25.8
26
*
G04BE08
ATC
tadalafil; oral
29.0
25.4
34
12
A46
ICD-10 Finland
Erysipelas
2.4
25.4
254
1210
B01AC11
ATC
iloprost; inhalant, parenteral
+∞
25.1
24
*
383
Kela drug reimbursment
Selexipag
+∞
25.1
24
*
B01AB10
ATC
tinzaparin; parenteral
3.4
24.9
130
416
ZX108
NOMESCO Finland
Inhalation
15.8
24.7
40
26
XF404
NOMESCO Finland
Ambulatory ECG
2.7
24.3
183
746
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
24.3
328
1786
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.6
24.3
200
859
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
3.3
24.1
129
420
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.2
24.1
283
1450
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
3.5
23.8
118
363
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
6.8
23.7
60
91
J96.0
ICD-10 Finland
Acute respiratory failure
7.3
23.5
57
81
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
19.9
23.5
35
18
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.5
23.5
197
851
R03AK07
ATC
formoterol and budesonide; inhalant
2.2
23.0
256
1278
R03BA02
ATC
budesonide; inhalant
2.2
23.0
258
1293
B01AC27
ATC
selexipag; oral
+∞
23.0
22
*
127
Kela drug reimbursment
Transplant complication
9.2
22.9
48
54
3AC01
NOMESCO Finland
NA
9.9
22.9
46
48
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.9
22.8
434
2693
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.9
22.6
447
2814
ZX120
NOMESCO Finland
Intravenous
2.6
22.5
174
718
R04.0
ICD-10 Finland
Epistaxis
2.8
22.3
153
587
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
3.0
22.1
133
470
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.1
21.7
275
1452
J45.1
ICD-10 Finland
Nonallergic asthma
3.1
21.6
125
430
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
5.1
21.4
69
142
R95
ICPC
Chron obstructive pulmonary disease
4.6
21.3
76
174
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
3.8
21.3
94
263
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
4.7
21.1
73
162
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
5.3
21.1
65
127
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
3.2
21.0
114
375
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
20.9
300
1663
R03AC12
ATC
salmeterol; inhalant
3.2
20.5
113
376
AP3
HP
Catheterization of the right and left side of the heart
18.6
20.5
31
17
I48.2
ICD-10 Finland
Chronic atrial fibrillation
4.5
20.3
73
169
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.7
20.1
143
560
C01BD01
ATC
amiodarone; systemic
4.2
20.0
78
195
M34.1
ICD-10 Finland
CR(E)ST syndrome
23.8
20.0
28
12
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
7.8
20.0
46
61
A12BA01
ATC
potassium chloride; oral
2.9
19.9
127
463
WX882
NOMESCO Finland
High dependency care
4.6
19.9
70
158
J96.9
ICD-10 Finland
Respiratory failure, unspecified
14.7
19.9
33
23
M10.9
ICD-10 Finland
Gout, unspecified
2.8
19.7
132
500
XW5WT
NOMESCO Finland
Other blood specimen with radiologicl guidance
29.4
19.7
26
9
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
8.3
19.5
43
53
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
9.3
19.4
40
44
Q21.10
ICD-10 Finland
Persistent ostium secundum
31.8
19.3
25
8
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.7
19.2
137
539
J01AA02
ATC
doxycycline; systemic
1.8
19.1
993
8273
J01MA14
ATC
moxifloxacin; systemic
2.6
18.8
150
629
L04AX01
ATC
azathioprine; systemic
3.9
18.8
79
212
K77
ICPC
Heart failure
4.2
18.2
70
173
J43.9
ICD-10 Finland
Emphysema, unspecified
5.9
17.9
50
87
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.1
17.9
235
1252
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
3.0
17.8
107
377
4151A
ICD-9 Finland
Acute pulmonary heart disease, Pulmonary embolism and infarction
+∞
17.7
17
*
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
5.8
17.6
50
89
E66.01
ICD-10 Finland
Obesity due to excess calories
3.3
17.6
93
300
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
96.3
17.6
19
*
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
11.7
17.5
32
28
62
HP
Catheterization and pressure measurement of the right side of the heart
17.2
17.4
27
16
3A064
NOMESCO Finland
NA
15.0
17.2
28
19
334
Kela drug reimbursment
Treprostinil
+∞
16.7
16
*
FBE32
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery
91.2
16.6
18
*
XG460
NOMESCO Finland
Short time oxymetry
5.3
16.5
50
97
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
12.3
16.4
29
24
R03AK08
ATC
formoterol and beclometasone; inhalant
3.9
16.3
68
182
WX722
NOMESCO Finland
PEEP
3.0
16.2
94
324
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.4
16.2
140
613
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
7.7
16.2
37
49
WX721
NOMESCO Finland
Oxygen concentrator therapy
30.4
16.1
21
7
R04.2
ICD-10 Finland
Haemoptysis
3.4
16.1
80
247
7AX01
NOMESCO Finland
NA
48.1
16.0
19
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
15.9
465
3228
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.7
15.8
70
197
GD1FN
NOMESCO Finland
Lung ventilation isotope imaging
60.7
15.8
18
*
I28.8
ICD-10 Finland
Other specified diseases of pulmonary vessels
+∞
15.6
15
*
B01AC21
ATC
treprostinil; parenteral
+∞
15.6
15
*
I28.9
ICD-10 Finland
Disease of pulmonary vessels, unspecified
+∞
15.6
15
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.0
15.4
90
313
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
7.1
14.9
36
52
R60.0
ICD-10 Finland
Localized oedema
2.1
14.8
181
929
N02AX02
ATC
tramadol; systemic, rectal
1.6
14.8
545
4002
M34.9
ICD-10 Finland
Systemic sclerosis, unspecified
21.3
14.7
21
10
42600
ICD-8 Finland
Pulmonary heart disease, Cor pulmonale
+∞
14.6
14
*
XF640
NOMESCO Finland
NA
3.5
14.5
67
196
C07AA07
ATC
sotalol; systemic
2.7
14.5
100
384
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.1
14.5
80
268
D64.9
ICD-10 Finland
Anaemia, unspecified
2.1
14.4
180
933
XF402
NOMESCO Finland
ECG with work load test
2.1
14.3
173
884
SPAT1262
SPAT
Handing over of treatment supplies
1.8
14.1
265
1599
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
14.0
562
4199
C09AA05
ATC
ramipril; oral
1.7
14.0
391
2658
J94.8
ICD-10 Finland
Other specified pleural conditions
5.2
13.7
42
83
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.4
13.7
66
200
R03BA05
ATC
fluticasone; inhalant
1.9
13.6
229
1327
S97
ICPC
Chronic ulcer skin
2.6
13.5
103
422
FXD00
NOMESCO Finland
Use of ECHLA without concurrent surgical procedure
141.3
13.5
14
*
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
7.8
13.4
30
39
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
26.0
13.4
18
7
R06.2
ICD-10 Finland
Wheezing
3.1
13.3
72
238
D68.8
ICD-10 Finland
Other specified coagulation defects
10.6
13.3
25
24
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
13.2
357
2399
4289X
ICD-9 Finland
Heart failure, unspecified
6.6
13.1
33
51
I83.2
ICD-10 Finland
Varicose veins of lower extremities with both ulcer and inflammation
9.4
13.0
26
28
A02BC02
ATC
pantoprazole; systemic
1.5
12.5
815
6751
742
NOMESCO Finland
NA
13.3
12.4
21
16
R4190
NOMESCO Finland
Nutritional therapy
3.7
12.4
54
151
B90.9
ICD-10 Finland
Sequelae of respiratory and unspecified tuberculosis
8.8
12.0
25
29
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
8.8
12.0
25
29
J01FA06
ATC
roxithromycin; oral
1.5
12.0
488
3620
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
2.4
11.9
102
445
GX2C5
NOMESCO Finland
Short-lasting oximetry
47.1
11.9
14
*
I48.1
ICD-10 Finland
Persistent atrial fibrillation
3.3
11.8
59
185
I42.5
ICD-10 Finland
Other restrictive cardiomyopathy
30.3
11.7
15
5
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
30.3
11.7
15
5
M34.0
ICD-10 Finland
Progressive systemic sclerosis
30.3
11.7
15
5
I34.1
ICD-10 Finland
Mitral (valve) prolapse
3.5
11.6
54
160
H02AB07
ATC
prednisone; oral
1.8
11.6
206
1213
TK810
NOMESCO Finland
Hemofiltration
11.2
11.5
21
19
42609
ICD-8 Finland
Pulmonary heart disease, Unspecified
+∞
11.5
11
*
PH7ZT
NOMESCO Finland
Intravenous removal of filter to inferior vena cava
+∞
11.5
11
*
FXE00
NOMESCO Finland
Use of ECLA
121.0
11.4
12
*
FXF00
NOMESCO Finland
Decannulation after ECHLA or ECLA
121.0
11.4
12
*
R03BB02
ATC
oxitropium bromide; inhalant
5.8
11.4
31
54
K99
ICPC
Cardiovascular disease other
3.2
11.3
58
185
WZC30
NOMESCO Finland
Teaching
1.9
11.3
165
908
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
6.6
11.3
28
43
I42.0
ICD-10 Finland
Dilated cardiomyopathy
3.2
11.3
58
186
284
Kela drug reimbursment
Nintedanib and pirfenidone
14.0
11.0
18
13
E87.5
ICD-10 Finland
Hyperkalaemia
4.2
11.0
41
101
C01DA14
ATC
isosorbide mononitrate; oral
1.6
10.9
300
2012
TK800
NOMESCO Finland
Hemodialysis
3.9
10.8
44
117
N18.8
ICD-10 Finland
Other chronic renal failure
3.2
10.7
55
176
J01FF01
ATC
clindamycin; systemic
1.6
10.7
321
2199
H02AB04
ATC
methylprednisolone; systemic
1.8
10.7
200
1195
N19
ICD-10 Finland
Unspecified kidney failure
2.7
10.7
71
269
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
3.9
10.6
42
109
GD1CQ
NOMESCO Finland
Lung circulation SPECT with low dose CT
60.5
10.6
12
*
GD1BT
NOMESCO Finland
Biopsy of lung with X-ray guidance
60.5
10.6
12
*
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
60.5
10.6
12
*
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.3
10.5
98
447
Z94.1
ICD-10 Finland
Heart transplant status
14.3
10.5
17
12
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.6
10.5
375
2679
XFE00
NOMESCO Finland
Epicardial ultrasonography
3.3
10.5
52
163
WW200
NOMESCO Finland
Immunization
3.7
10.4
45
126
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.3
10.4
94
419
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.9
10.4
151
828
PH3BC
NOMESCO Finland
Extensive flebography of internal organs with X-ray
110.8
10.4
11
*
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
110.8
10.4
11
*
GD1CN
NOMESCO Finland
Lung circulation isotope imaging
+∞
10.4
10
*
4160A
ICD-9 Finland
Chronic pulmonary heart disease, Primary pulmonary hypertension
+∞
10.4
10
*
R50.9
ICD-10 Finland
Fever, unspecified
1.8
10.4
191
1137
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.7
10.3
72
280
GD1LA
NOMESCO Finland
GD
4.8
10.3
33
70
J01CA04
ATC
amoxicillin; systemic
1.5
10.2
929
8079
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.2
10.1
103
490
B01AB04
ATC
dalteparin; parenteral
2.5
10.0
80
335
J92.0
ICD-10 Finland
Pleural plaque with presence of asbestos
3.5
10.0
46
136
I47.1
ICD-10 Finland
Supraventricular tachycardia
2.8
10.0
63
232
L04AD01
ATC
ciclosporin; systemic
4.8
10.0
32
68
R58
ICD-10 Finland
Haemorrhage, not elsewhere classified
4.5
10.0
34
77
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
4.5
10.0
34
77
K07
ICPC
Swollen ankles/oedema
2.4
9.9
80
340
R03AC13
ATC
formoterol; inhalant
2.5
9.8
77
322
SPAT1263
SPAT
Sampling
1.5
9.8
513
3976
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
2.4
9.8
83
362
B01AF01
ATC
rivaroxaban; oral
1.8
9.7
161
925
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
13.5
9.7
16
12
Q25.0
ICD-10 Finland
Patent ductus arteriosus
55.4
9.7
11
*
1CX08
NOMESCO Finland
NA
7.9
9.6
21
27
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
5.5
9.5
27
50
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
2.8
9.5
61
228
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.3
9.5
85
378
Q21.81
ICD-10 Finland
Eisenmenger's syndrome
100.7
9.4
10
*
XX4BW
NOMESCO Finland
NA
30.2
9.4
12
*
JN3AD
NOMESCO Finland
Abdominal CT examination
2.1
9.4
104
510
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
2.8
9.4
57
206
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.3
9.4
88
403
FKE05
NOMESCO Finland
Mitral valvuloplasty
+∞
9.4
9
*
G30.1
ICD-10 Finland
Alzheimer disease with late onset
0.3
9.3
22
671
P01BA02
ATC
hydroxychloroquine; oral
2.1
9.3
104
516
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.6
9.3
40
113
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.9
9.2
54
190
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
9.2
203
1272
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.5
9.2
42
124
356
Kela drug reimbursment
Nintedanib and pirfenidone
13.8
9.2
15
11
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
13.8
9.2
15
11
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.9
9.2
133
728
TKC20
NOMESCO Finland
Catheterisation of bladder
2.0
9.1
117
614
D75.1
ICD-10 Finland
Secondary polycythaemia
7.1
9.0
21
30
UJF32
NOMESCO Finland
Coloscopy
1.5
9.0
325
2315
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
8.9
384
2847
Q21.19
ICD-10 Finland
Atrial septal defect NOS
12.6
8.9
15
12
R18
ICD-10 Finland
Ascites
3.7
8.9
37
102
R60.9
ICD-10 Finland
Oedema, unspecified
2.4
8.8
73
314
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.7
8.8
57
215
E66.00
ICD-10 Finland
Metabolic syndrome
2.5
8.7
66
270
K82
ICPC
Pulmonary heart disease
50.3
8.7
10
*
FQA10
NOMESCO Finland
Orthotopic transplantation of heart with bicaval anastomosis
50.3
8.7
10
*
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.1
8.7
93
454
AP1
HP
Catheterization of the left side of the heart
3.4
8.6
40
120
N06DX01
ATC
memantine; oral
0.4
8.6
27
726
R03AK11
ATC
formoterol and fluticasone; inhalant
3.8
8.6
35
95
TFC20
NOMESCO Finland
Catheterisation of both sides of heart
16.4
8.6
13
8
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.4
8.5
71
307
R03AL03
ATC
vilanterol and umeclidinium bromide; inhalant
4.6
8.5
28
62
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.8
8.5
142
816
ZX199
NOMESCO Finland
Other rote
27.7
8.5
11
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.8
8.5
159
949
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
2.3
8.4
76
341
SPAT1059
SPAT
Spirometry at the office
2.4
8.4
71
311
SPAT1255
SPAT
Intravenous administration of medicine
2.1
8.3
94
466
TFP34
NOMESCO Finland
Electrophysiological investigation
3.5
8.3
37
108
RS221
NOMESCO Finland
NA
4.8
8.3
26
55
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
7.1
8.3
19
27
M10.0
ICD-10 Finland
Idiopathic gout
2.7
8.2
53
199
R03BA08
ATC
ciclesonide; inhalant
2.1
8.2
96
484
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.7
8.2
56
216
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.7
8.2
189
1201
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
8.1
306
2195
103
Kela drug reimbursment
Diabetes, insulin-treated
1.5
8.1
357
2649
I20.99
ICD-10 Finland
Angina pectoris, unspecified
1.9
8.1
117
639
SPAT1254
SPAT
Administration of medicine
1.6
8.1
209
1369
FXL00
NOMESCO Finland
Insertion and use of extra-, para- or intracorporeal VAD
33.5
8.1
10
*
A07AA09
ATC
vancomycin; oral
4.9
8.1
25
52
C08CA01
ATC
amlodipine; oral
1.4
8.0
482
3802
R03AC03
ATC
terbutaline; inhalant
1.7
7.9
163
1003
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.5
7.9
365
2732
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.2
7.9
80
379
M10
ICD-10 Finland
Gout
2.3
7.9
70
313
L04AX05
ATC
pirfenidone; oral
13.1
7.9
13
10
I87.0
ICD-10 Finland
Postthrombotic syndrome
13.1
7.9
13
10
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.2
7.9
39
124
XPX04
NOMESCO Finland
Angioscopy
10.9
7.8
14
13
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
7.8
375
2831
DKW00
NOMESCO Finland
Cauterisation of mucosa of nose
5.1
7.7
23
46
RD210
NOMESCO Finland
NA
4.3
7.7
27
64
GX2D5
NOMESCO Finland
Sleep oximetry
15.1
7.7
12
8
XV5WT
NOMESCO Finland
NA
45.2
7.7
9
*
TPW99
NOMESCO Finland
Other minor surgical procedure on peripheral vessel or lymphatic system
4.6
7.7
25
55
J45.8
ICD-10 Finland
Mixed asthma
2.7
7.6
49
184
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
7.6
123
702
XA421
NOMESCO Finland
Nocturnal polygraphy
25.1
7.6
10
*
I34.9
ICD-10 Finland
Nonrheumatic mitral valve disorder, unspecified
5.2
7.6
22
43
C09AA02
ATC
enalapril; systemic
1.5
7.5
291
2097
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.6
7.5
191
1244
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.5
7.5
56
230
N17.8
ICD-10 Finland
Other acute renal failure
4.9
7.5
23
48
T90
ICPC
Diabetes non-insulin dependent
1.5
7.4
281
2013
4912A
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS CHRONICA OBSTRUCTIVA]
5.1
7.4
22
44
E66.8
ICD-10 Finland
Other obesity
2.8
7.4
47
174
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.0
7.4
94
491
J61
ICD-10 Finland
Pneumoconiosis due to asbestos and other mineral fibres
4.8
7.3
23
49
J69.1
ICD-10 Finland
Pneumonitis due to oils and essences
+∞
7.3
7
*
AE1
HP
Pulmonary artery thrombendarterectomy
+∞
7.3
7
*
I27
ICD-10 Finland
Other pulmonary heart diseases
+∞
7.3
7
*
Q21.9
ICD-10 Finland
Congenital malformation of cardiac septum, unspecified
+∞
7.3
7
*
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
3.6
7.3
31
88
R05CB01
ATC
acetylcysteine; inhalant, oral
3.3
7.3
34
104
R03DC03
ATC
montelukast; oral
1.7
7.3
158
986
N05CF01
ATC
zopiclone; oral
1.4
7.3
426
3330
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
2.9
7.2
42
149
A10BB12
ATC
glimepiride; oral
1.8
7.2
126
739
C08DA01
ATC
verapamil; systemic
2.1
7.2
73
350
FFC00
NOMESCO Finland
Suture of ostium secundum type ASD
30.2
7.1
9
*
3A422
NOMESCO Finland
NA
20.1
7.1
10
5
JN4AD
NOMESCO Finland
Body CT examination
1.9
7.1
98
528
R94.2
ICD-10 Finland
Abnormal results of pulmonary function studies
6.6
7.1
17
26
RK320
NOMESCO Finland
NA
4.6
7.1
23
51
RK110
NOMESCO Finland
NA
4.7
7.0
22
47
J46
ICD-10 Finland
Status asthmaticus
2.9
7.0
40
139
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
7.0
332
2492
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
2.2
7.0
66
305
A10BA02
ATC
metformin; oral
1.4
6.9
356
2711
C03AA03
ATC
hydrochlorothiazide; oral
1.7
6.9
145
896
A10BH05
ATC
linagliptin; oral
2.1
6.9
75
368
J47
ICD-10 Finland
Bronchiectasis
3.2
6.9
34
109
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.5
6.9
291
2135
M35.1
ICD-10 Finland
Other overlap syndromes
8.3
6.8
14
17
WX730
NOMESCO Finland
Conventional respirator
3.5
6.8
30
88
M01AH05
ATC
etoricoxib; oral
0.7
6.8
390
4852
348
Kela drug reimbursment
Roflumilast
11.0
6.8
12
11
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
6.8
221
1531
C09DX04
ATC
valsartan and sacubitril; oral
5.3
6.8
19
36
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
3.2
6.8
33
105
ZX197
NOMESCO Finland
NA
40.2
6.8
8
*
120
NOMESCO Finland
NA
40.2
6.8
8
*
3A149
NOMESCO Finland
NA
40.2
6.8
8
*
TLC00
NOMESCO Finland
Insertion of intrauterine device
3.0
6.7
36
122
RS222
NOMESCO Finland
NA
4.3
6.7
23
54
JN4BD
NOMESCO Finland
Extensive body CT
1.7
6.7
142
881
TQW80
NOMESCO Finland
Local dermatologic skincare
2.8
6.7
40
145
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.1
6.7
76
380
474
NOMESCO Finland
NA
22.6
6.7
9
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.0
6.7
76
382
C01BC04
ATC
flecainide; systemic
2.4
6.7
54
233
XW000
NOMESCO Finland
Bone marrow biopsy
2.3
6.6
59
268
49104
ICD-8 Finland
Chronic bronchitis, Cum emphysemate
6.9
6.5
15
22
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
2.7
6.5
40
149
K84
ICPC
Heart disease other
2.5
6.5
47
192
XG474
NOMESCO Finland
Exhalation nntrogen oxide
2.9
6.5
37
129
A08
ICPC
Swelling
2.2
6.5
65
309
I34.0
ICD-10 Finland
Mitral (valve) insufficiency
3.4
6.5
29
87
74709
ICD-8 Finland
Other congenital anomalies of circulatory system, Patent ductus arteriosus
70.2
6.4
7
*
I49.5
ICD-10 Finland
Sick sinus syndrome
2.1
6.4
68
333
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.9
6.4
92
502
289
Kela drug reimbursment
Combination product containing sacubitril and valsartan
4.7
6.4
20
43
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.5
6.4
241
1721
GBB00
NOMESCO Finland
Tracheostomy
3.9
6.4
24
62
J01DA01
ATC
[U] cefalexin; systemic
1.3
6.4
727
6298
I35.0
ICD-10 Finland
Aortic (valve) stenosis
1.8
6.4
101
573
J20
ICD-10 Finland
Acute bronchitis
1.8
6.3
103
590
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
8.2
6.3
13
16
UJF30
NOMESCO Finland
Ileoscopy through colon
1.8
6.3
106
612
R24
ICPC
Haemoptysis
6.0
6.3
16
27
XX9XE
NOMESCO Finland
Other ultrasound examination
6.0
6.3
16
27
2BD01
NOMESCO Finland
NA
11.1
6.3
11
10
K63.5
ICD-10 Finland
Polyp of colon
4.6
6.3
20
44
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.2
6.3
60
281
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
2.9
6.3
36
126
J01DB01
ATC
cefalexin; oral
1.4
6.3
927
8342
FPH10
NOMESCO Finland
Open removal of transvenous cardiac pacemaker or cardioverter-defibrillator
18.1
6.3
9
5
Q21.18
ICD-10 Finland
Other spedified atrial septal defect
+∞
6.3
6
*
45001
ICD-8 Finland
Pulmonary embolism and infarction, Embolia
+∞
6.3
6
*
FB1CC
NOMESCO Finland
Very extensive angiography of arteria pulmonalis
+∞
6.3
6
*
C08DB01
ATC
diltiazem; oral
1.8
6.2
106
617
5AB14
NOMESCO Finland
NA
26.8
6.2
8
*
R96
ICPC
Asthma
1.8
6.2
98
557
RF410
NOMESCO Finland
NA
5.4
6.2
17
32
RF420
NOMESCO Finland
NA
4.2
6.1
21
50
J01FA15
ATC
telithromycin; oral
1.8
6.1
99
565
WX720
NOMESCO Finland
Own respiration
2.5
6.1
44
179
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
6.1
199
1381
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
0.3
6.1
9
348
XX1XW
NOMESCO Finland
Extensive written report from radiologist
2.9
6.1
35
124
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
6.1
277
2057
A40.8
ICD-10 Finland
Other streptococcal sepsis
4.9
6.1
18
37
J43.2
ICD-10 Finland
Centrilobular emphysema
10.1
6.0
11
11
FPE00
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with ventricular electrode
2.5
6.0
46
191
I80.1
ICD-10 Finland
Phlebitis and thrombophlebitis of femoral vein
3.6
6.0
25
71
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
243
279
10.19
199.28
6.4
2.2
92.3
87.1
%
2.30
237
264
159
92
19.20
197.25
1.4
1.1
95.9
116.6
%
5.64
150
84
161
98
18.27
194.87
1.6
1.2
7.4
4.5
u/ml
0.31
63
32
226
249
10.50
190.85
6.1
2.3
201.7
200.2
%
0.07
220
237
970
4179
4.70
187.55
9.1
3.1
2502.2
1871.1
ng/l
3.26
922
3594
157
102
17.06
183.73
1.6
1.2
3.9
5.9
u/ml
0.42
87
47
147
89
18.19
178.15
1.3
1.1
—
—
—
0
0
522
1507
4.77
169.14
11.9
7.1
5.2
5.1
kpa
0.83
507
1423
522
1508
4.76
168.97
11.8
7.1
9.4
11.7
kpa
25.98
506
1425
513
1505
4.65
162.01
12.1
7.1
2.1
1.1
mmol/l
4.29
414
1157
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
271
454
7.06
160.15
7.0
2.4
0.3
0.4
u/ml
0.55
190
260
544
1725
4.37
154.06
4.0
2.6
17.6
22.1
%
13.14
494
1463
582
1986
4.14
148.14
4.2
2.5
10.8
12.2
umol/l
4.99
568
1823
551
1832
4.16
145.01
4.0
2.5
2.4
2.3
g/l
6.81
537
1681
449
1346
4.33
135.10
12.7
7.5
92.2
95.4
%
11.29
437
1288
300
683
5.23
126.94
14.3
9.3
24.8
24.4
mmol/l
1.01
278
637
413
1254
4.16
120.78
7.4
3.1
396.7
244.4
ng/l
5.37
389
1152
380
1144
4.10
111.67
13.8
6.8
12.1
10.9
mmol/l
1.96
369
1083
578
2343
3.38
107.67
5.2
1.6
1.5
1.4
mg/l
0.44
469
1819
177
290
6.78
105.46
1.8
1.4
0.2
0.2
g/l
0.09
169
276
178
305
6.48
101.42
1.8
1.4
1.2
1.2
g/l
0.03
170
290
94
72
13.86
99.72
1.2
1.1
—
—
—
0
0
94
72
13.86
99.72
1.2
1.1
—
—
—
0
0
94
73
13.67
98.91
1.2
1.1
—
—
—
0
0
94
73
13.67
98.91
1.2
1.1
—
—
—
0
0
94
73
13.67
98.91
1.2
1.1
—
—
—
0
0
73
35
21.87
97.64
1.3
1.2
—
—
—
0
0
921
5325
2.87
85.28
26.9
10.2
1.7
1.3
inr
13.56
298
1431
268
766
4.04
82.96
7.8
4.3
2.6
1.9
mmol/l
2.00
225
563
272
813
3.86
78.80
8.0
4.4
5.4
5.2
kpa
2.45
263
746
331
1133
3.46
78.08
2.1
2.7
65.1
66.1
g/l
1.46
310
1018
668
3409
2.72
76.66
3.9
2.2
4.0
3.0
mg/l
7.19
615
2852
621
3068
2.74
75.82
6.0
2.8
1110.1
8389.7
umol/l
7.76
571
2575
143
266
5.83
74.42
2.6
1.6
—
—
—
0
0
456
1935
2.94
74.17
8.1
3.1
0.8
0.8
mmol/l
0.14
435
1794
503
2269
2.83
72.76
2.7
1.9
—
—
—
0
0
413
1681
3.01
72.21
7.8
5.4
1.1
1.0
mmol/l
5.15
390
1534
377
1473
3.08
70.72
5.7
3.8
286.5
248.9
u/l
2.32
365
1381
335
1228
3.22
70.05
15.2
8.0
125.0
119.8
g/l
3.65
328
1178
95
122
8.24
69.94
2.9
1.5
—
—
—
0
0
143
283
5.48
69.52
2.7
1.5
—
—
—
0
0
139
274
5.49
67.84
9.9
4.4
3.1
2.8
mmol/l
0.45
113
186
118
199
6.35
67.80
2.7
1.6
—
—
—
0
0
182
471
4.26
63.81
3.7
2.8
—
—
—
0
0
103
163
6.71
62.90
2.6
1.5
—
—
—
0
0
113
202
5.97
61.12
2.4
1.4
—
—
—
0
0
868
5404
2.43
60.84
10.8
5.8
22.2
26.5
%
23.77
831
4986
137
293
5.04
60.84
2.3
1.4
—
—
—
0
0
808
4921
2.38
58.87
7.5
4.1
64.6
61.5
ng/l
0.04
694
3731
374
1593
2.79
58.74
2.6
1.8
—
—
—
0
0
426
1951
2.65
57.88
7.0
2.0
33.9
30.1
s
15.57
420
1887
372
1591
2.78
57.88
2.6
1.8
—
—
—
0
0
951
6247
2.41
57.83
11.9
5.8
15.1
12.0
umol/l
11.58
922
5893
419
1906
2.66
57.69
43.6
29.1
1.9
1.4
inr
5.30
39
259
320
1277
2.91
56.62
5.4
3.7
3.0
1.9
mmol/l
3.20
254
1002
845
5306
2.35
56.55
10.4
5.5
62.4
58.3
%
19.51
812
4923
321
1290
2.89
56.02
5.3
3.7
6.2
5.8
kpa
4.40
306
1251
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
47
29
16.70
55.74
1.5
2.4
165.0
181.4
%
0.30
47
29
134
305
4.72
55.15
5.8
4.5
7.5
8.0
kpa
2.02
125
273
96
165
6.15
53.98
2.5
1.4
—
—
—
0
0
166
453
3.99
53.90
1.6
1.9
36.3
38.4
u/l
0.56
144
394
857
5487
2.30
53.76
7.5
4.6
33.7
34.7
g/l
5.77
815
5065
368
1629
2.67
53.01
15.2
6.8
103.7
104.3
mmol/l
1.21
359
1590
496
2547
2.41
51.93
6.9
4.1
2354.3
372.7
ng/l
0.65
463
2163
200
635
3.48
51.89
5.0
4.0
24.8
24.0
mmol/l
1.86
174
580
612
3465
2.29
50.84
7.3
3.0
32.6
35.0
u/l
0.52
585
3276
232
827
3.13
49.74
11.1
6.7
25.3
24.5
mmol/l
1.75
225
769
69
91
7.90
49.54
3.5
1.6
—
—
—
0
0
231
824
3.13
49.45
3.8
2.5
10.8
10.9
g/l
0.11
221
745
42
28
15.40
47.80
5.0
7.1
—
—
—
0
0
167
497
3.65
47.70
2.0
2.5
10.3
10.6
g/l
0.24
147
424
133
341
4.18
46.88
1.4
1.2
2.5
1.1
u/ml
—
8
29
97
193
5.30
46.62
16.6
5.8
667.2
1000.4
iu/ml
0.16
31
28
33
14
24.08
45.93
3.7
1.7
—
—
—
0
0
128
325
4.21
45.68
5.5
3.8
25.7
24.9
mmol/l
0.86
117
278
755
4797
2.15
45.62
4.9
2.8
129.6
143.8
ug/l
0.82
716
4315
141
386
3.93
45.40
2.1
1.5
114.5
140.0
titre
0.21
11
15
169
526
3.49
45.02
2.0
2.4
3.7
3.8
g/l
0.43
135
384
169
527
3.49
44.88
2.0
2.4
—
—
—
0
0
169
528
3.48
44.75
2.0
2.4
7.0
7.5
g/l
3.65
137
399
141
392
3.86
44.40
2.1
2.5
0.0
0.0
g/l
0.74
133
359
165
512
3.50
44.14
9.4
4.6
25.4
24.9
mmol/l
0.96
158
475
349
1634
2.48
43.83
3.6
2.4
2.0
1.8
%
3.60
325
1426
136
374
3.90
43.48
2.1
2.5
0.0
0.0
g/l
0.00
128
343
135
370
3.91
43.36
2.1
2.5
0.0
0.0
g/l
0.00
128
342
189
646
3.20
43.25
2.1
1.8
1.3
1.5
g/l
3.07
165
554
150
446
3.62
42.79
2.1
2.6
0.8
1.5
g/l
1.19
135
383
158
489
3.49
42.39
2.0
2.4
3.1
3.2
g/l
0.51
137
392
524
2980
2.16
41.16
9.6
3.9
69.1
85.1
%
25.48
514
2911
142
422
3.61
40.49
2.1
2.4
37.5
36.8
g/l
0.88
129
361
40
33
12.42
40.27
28.7
33.1
155.5
129.7
ug/l
0.74
25
28
900
6292
2.07
40.14
13.3
6.8
1.2
1.2
mmol/l
17.54
758
5276
839
5738
2.04
39.52
13.2
6.0
1.2
1.2
mmol/l
16.44
785
5126
267
1154
2.60
39.35
2.4
2.2
0.2
0.2
g/l
3.34
250
1069
270
1176
2.58
39.15
16.6
6.8
1.6
1.4
mmol/l
1.31
264
1125
130
373
3.72
39.03
3.4
3.0
0.9
0.8
nmol/l
0.67
102
287
918
6555
2.02
37.48
13.1
8.2
4.8
4.3
e9/l
8.20
840
5664
78
157
5.18
36.95
1.8
1.4
—
—
—
0
0
83
178
4.88
36.54
1.9
1.3
—
—
—
0
0
186
696
2.91
36.10
22.5
10.1
—
—
—
0
0
76
154
5.14
35.72
6.0
2.9
160.8
1684.8
u/ml
—
6
12
39
40
9.98
33.97
1.4
1.1
1.2
1.1
ratio
—
16
10
97
252
4.04
33.45
3.7
2.4
15.6
15.5
%
0.01
50
119
39
42
9.51
32.78
3.1
1.5
—
—
—
0
0
144
494
3.12
32.49
4.8
2.2
372.3
462.8
ug/l
0.32
137
458
240
1077
2.46
32.27
4.8
3.1
4.3
4.6
kpa
1.58
225
1041
155
558
2.98
32.15
2.6
1.8
1.8
2.0
ug/l
0.09
139
480
98
264
3.90
32.13
2.9
2.2
125.8
127.4
g/l
0.18
62
188
69
142
5.04
31.85
3.5
3.5
—
—
—
0
0
97
263
3.87
31.51
3.2
2.5
36.5
33.6
umol/l
0.32
87
215
75
171
4.56
30.64
1.6
1.4
116.7
108.5
u/ml
0.28
12
27
53
89
6.14
30.42
2.1
1.4
—
—
—
0
0
104
320
3.42
27.98
2.2
1.8
—
—
—
0
0
51
90
5.83
27.83
1.1
1.0
—
—
—
0
0
453
2748
1.93
27.67
3.8
2.6
5.4
5.2
e6/l
0.13
405
2420
41
58
7.24
27.64
2.1
1.3
—
—
—
0
0
41
58
7.24
27.64
2.2
1.3
—
—
—
0
0
109
355
3.23
26.76
2.2
1.6
—
—
—
0
0
83
227
3.81
26.62
1.5
1.2
18.0
2.6
u/ml
0.44
11
15
267
1355
2.18
26.58
3.2
2.7
10.1
9.4
umol/l
0.33
241
1179
32
35
9.32
26.56
1.3
1.1
63.8
17.1
u/ml
—
5
7
95
290
3.43
25.86
1.5
1.2
32.1
36.1
u/ml
—
8
11
45
76
6.07
25.68
2.0
1.3
—
—
—
0
0
91
273
3.48
25.45
1.6
1.2
10.8
2.8
u/ml
0.51
18
26
306
1665
2.05
25.26
1.3
1.2
34.4
37.5
iu/ml
0.17
95
526
91
276
3.44
25.02
1.6
1.2
16.2
8.2
u/ml
0.40
23
49
936
7218
1.78
25.02
12.3
4.8
6.8
6.8
mmol/l
0.11
907
6755
203
942
2.33
24.99
1.9
1.6
—
—
—
0
0
342
1954
1.97
24.53
2.0
1.4
2.7
2.6
g/l
0.51
245
1122
140
552
2.69
24.36
1.5
1.2
325.5
264.6
u/ml
0.28
133
498
185
839
2.37
23.96
5.7
3.2
128.1
125.6
g/l
0.68
176
816
65
161
4.17
23.88
1.2
1.1
—
—
—
0
0
648
4571
1.73
23.09
4.7
3.4
—
—
—
0
0
243
1263
2.10
22.49
2.8
2.6
19.6
6.6
ug/l
3.05
212
1072
66
173
3.94
22.47
1.3
1.2
380.5
293.4
u/ml
0.86
46
87
63
160
4.07
22.39
7.6
6.6
11.1
12.2
mg/l
1.11
55
151
70
192
3.77
22.36
3.6
2.8
4.9
4.5
e9/l
0.78
70
192
72
202
3.69
22.26
4.1
3.0
64.5
59.9
%
2.08
72
202
140
579
2.56
22.09
1.1
1.2
217.2
147.7
iu/ml
0.42
23
211
47
97
4.97
21.63
1.1
1.1
—
—
—
0
0
74
218
3.52
21.28
1.5
1.5
28.1
30.3
g/l
0.80
67
196
202
1005
2.17
20.85
2.1
2.0
353.2
377.7
nmol/l
0.69
185
905
66
183
3.73
20.76
1.3
1.2
—
—
—
0
0
134
560
2.53
20.67
5.7
5.3
1.9
1.6
%
1.14
124
524
91
312
3.04
20.46
1.5
1.4
—
—
—
0
0
91
312
3.04
20.46
1.5
1.4
—
—
—
0
0
33
52
6.47
20.14
25.2
1.3
84.7
62.7
mg/l
0.63
26
40
534
3679
1.70
20.00
3.1
2.4
61.0
58.2
u/l
0.45
511
3364
50
118
4.35
19.58
2.5
1.7
—
—
—
0
0
519
3566
1.69
19.54
4.6
3.3
0.9
0.5
e6/l
2.10
438
2744
112
447
2.63
18.97
2.6
3.2
1.7
1.8
ratio
0.01
13
35
114
460
2.60
18.89
2.6
3.2
58.6
66.3
mg/l
0.19
85
384
93
343
2.82
18.35
1.5
1.5
—
—
—
0
0
1080
9021
1.69
18.33
15.6
7.2
88.9
81.3
u/l
5.49
1040
8380
83
288
2.99
18.29
1.8
2.0
10.7
12.4
mg/l
0.94
77
265
61
176
3.57
18.12
1.4
1.4
15604.8
101611.1
e6/l
1.46
39
109
112
460
2.55
17.89
2.6
3.2
39.9
48.4
mg/l
0.34
83
386
537
3792
1.65
17.83
3.6
2.2
187.6
219.4
u/l
0.43
508
3527
50
128
4.01
17.61
2.6
1.7
—
—
—
0
0
52
139
3.84
17.26
1.6
1.2
92.8
69.2
u/ml
—
6
7
145
686
2.23
16.86
5.4
3.2
26.0
25.0
mmol/l
1.59
138
664
162
803
2.14
16.77
1.9
1.5
—
—
—
0
0
126
564
2.35
16.69
3.5
3.2
4.0
4.4
pmol/l
5.20
113
482
20
22
9.20
16.45
1.2
1.0
—
—
—
0
0
63
198
3.28
16.40
1.4
1.4
835.6
1488.4
e6/l
2.41
49
145
232
1329
1.88
15.94
5.5
3.6
—
—
—
0
0
193
1040
1.98
15.91
5.6
3.3
1.2
1.2
mmol/l
2.26
180
884
79
290
2.82
15.74
3.8
3.7
2.1
1.7
mg/l
2.30
73
261
63
205
3.16
15.51
1.7
1.2
75.2
44.0
u/ml
—
10
19
42
104
4.13
15.48
1.2
1.1
—
—
u/ml
—
0
0
16
14
11.54
15.33
1.1
1.1
—
—
—
0
0
1002
8462
1.55
13.86
8.8
4.1
16.9
14.2
mm/h
5.19
954
7692
93
398
2.42
13.62
7.8
3.7
4.0
3.9
mmol/l
0.13
82
371
40
106
3.85
13.47
1.5
1.4
13.7
14.3
u/l
0.21
40
99
28
56
5.08
13.39
2.4
2.1
—
—
—
0
0
28
56
5.08
13.39
2.1
2.0
12.2
13.2
%
0.11
13
29
22
35
6.36
13.30
1.9
1.1
17.9
15.6
g/l
0.69
22
24
96
436
2.28
12.30
1.4
1.3
—
—
—
0
0
18
26
6.99
11.87
1.4
1.2
—
—
—
0
0
33
86
3.90
11.40
1.1
1.1
386.0
187.1
titre
—
5
14
113
566
2.08
11.35
2.3
1.9
—
—
—
0
0
58
216
2.75
11.30
1.1
1.2
40.7
43.1
u/l
0.06
51
186
27
62
4.42
11.00
2.5
2.1
500.0
508.2
e6/l
0.03
22
53
53
192
2.82
10.88
4.6
4.1
1.7
1.4
%
0.25
39
152
66
269
2.52
10.77
2.2
1.6
—
—
—
0
0
28
68
4.18
10.63
4.3
3.6
—
—
—
0
0
19
33
5.82
10.55
4.8
2.1
—
—
—
0
0
19
33
5.82
10.55
4.8
2.1
—
—
—
0
0
22
44
5.06
10.53
2.0
1.3
—
—
—
0
0
102
515
2.05
10.04
2.1
1.8
—
—
—
0
0
15
22
6.88
9.74
1.1
1.1
—
—
—
0
0
401
2963
1.48
9.69
3.3
2.5
—
—
—
0
0
36
112
3.27
9.62
1.4
1.5
—
—
—
0
0
36
112
3.27
9.62
1.4
1.5
—
—
—
0
0
36
112
3.27
9.62
1.4
1.5
—
—
—
0
0
932
8047
1.41
9.37
6.9
5.0
1193.3
2237.7
e6/l
0.36
24
130
168
1020
1.73
9.34
4.0
3.9
129.1
93.3
ng/l
3.09
142
866
381
2822
1.47
9.00
2.0
1.8
1239.8
1170.9
nmol/l
0.67
311
2069
17
31
5.53
8.98
1.2
1.2
—
—
—
0
0
150
895
1.75
8.86
2.1
1.7
—
—
—
0
0
545
4322
1.41
8.84
4.0
3.3
2.3
2.4
mmol/l
1.60
474
3680
36
119
3.07
8.73
1.0
1.0
—
—
—
0
0
34
109
3.17
8.68
1.2
1.2
51.7
59.2
u/l
0.27
23
76
15
25
6.05
8.66
2.8
1.6
31.1
27.9
g/l
0.34
15
20
28
83
3.42
8.09
1.8
1.3
—
—
—
0
0
285
2072
1.46
7.25
3.9
3.1
2.4
2.2
e6/l
0.21
160
1171
12
19
6.36
7.25
2.7
1.6
—
—
—
0
0
23
65
3.58
7.15
1.5
1.5
—
—
—
0
0
23
65
3.58
7.15
1.5
1.5
—
—
—
0
0
23
65
3.58
7.15
1.5
1.5
—
—
—
0
0
23
65
3.58
7.15
1.5
1.5
—
—
—
0
0
23
66
3.52
7.00
2.2
2.1
886.5
683.4
e6/l
—
10
27
44
185
2.42
6.82
1.3
1.2
—
—
—
0
0
109
641
1.76
6.80
5.2
2.6
0.6
0.7
%
0.40
104
617
21
59
3.60
6.60
2.1
2.5
1815.0
1337.1
u/ml
0.29
21
59
148
957
1.61
6.46
1.4
1.7
1.7
1.5
%
1.11
124
797
407
3220
1.36
6.28
1.7
1.6
18.1
20.2
nmol/l
2.23
367
2691
62
312
2.03
6.25
1.6
1.5
134.5
2.2
iu/ml
—
9
68
770
6682
1.31
6.23
4.7
3.1
78.3
52.4
u/l
10.21
732
6092
390
3091
1.35
5.90
6.0
4.3
0.0
0.0
estimate
0.50
195
987
645
5497
1.30
5.84
5.7
4.2
—
—
—
0
0
462
3775
1.32
5.64
3.6
3.1
6.4
7.1
mmol/l
3.21
392
3079
24
83
2.92
5.47
1.5
1.3
—
—
—
0
0
24
83
2.92
5.47
1.5
1.3
—
—
—
0
0
994
10796
0.77
5.38
5.4
4.9
6.1
6.1
mmol/l
0.13
884
9573
562
4746
1.29
5.31
2.9
2.2
79.0
78.8
nmol/l
0.04
486
4100
16
44
3.66
5.21
1.1
1.3
40.7
82.2
ug/l
—
9
21
17
49
3.50
5.18
1.6
1.6
—
—
—
0
0
17
49
3.50
5.18
1.6
1.6
—
—
—
0
0
161
1118
1.49
5.12
2.4
2.3
58.3
34.3
u/l
0.77
139
943
17
50
3.43
5.03
1.6
1.6
—
—
—
0
0
137
923
1.53
5.03
3.8
3.1
53.8
60.4
ml/min/173m2
1.05
69
396
27
105
2.60
4.98
1.3
1.3
—
—
—
0
0
20
67
3.01
4.83
1.3
1.2
158.0
76.3
u/l
1.39
15
59
22
79
2.81
4.72
1.5
1.4
—
—
—
0
0
22
79
2.81
4.72
1.5
1.4
—
—
—
0
0
20
68
2.97
4.72
1.7
1.6
19.7
9.0
u/l
0.45
12
37
56
304
1.87
4.61
2.3
2.4
145.8
82.3
ug/min
0.56
28
181
20
69
2.92
4.61
1.7
1.2
—
—
—
0
0
1015
10925
0.78
4.58
5.4
5.2
2.3
2.6
mmol/l
25.25
929
9821
19
64
2.99
4.56
1.3
1.2
37.1
19.1
u/l
1.30
14
55
9
11
8.22
4.56
1.1
1.0
—
—
—
0
0
282
2207
1.34
4.53
3.7
2.9
1.4
1.1
e6/l
0.45
162
1294
23
87
2.67
4.50
1.7
2.3
541.8
612.9
ml
0.41
11
52
44
224
1.99
4.38
1.8
1.7
6.3
5.4
iu/l
0.15
15
65
987
10633
0.79
4.30
5.0
4.6
4.1
4.5
mmol/l
27.73
912
9608
464
3907
1.27
4.30
4.4
3.9
20.9
14.0
mg/mmol
0.59
331
2450
59
336
1.79
4.20
1.2
1.2
—
—
—
0
0
977
10527
0.80
4.20
5.0
4.6
1.3
1.5
mmol/l
15.92
897
9429
211
1597
1.37
4.20
1.3
1.2
14.8
11.5
u/ml
0.24
61
557
59
338
1.78
4.12
1.3
1.2
—
—
—
0
0
47
257
1.86
3.84
1.2
1.3
—
—
—
0
0
6
5
12.04
3.76
1.0
1.8
—
—
—
0
0
18
66
2.75
3.76
1.8
1.4
72.4
61.7
%
0.58
13
49
28
566
0.49
3.68
1.4
1.7
—
—
—
0
0
613
5400
1.23
3.67
2.2
2.1
89.3
93.3
pmol/l
1.21
352
2736
30
142
2.14
3.66
2.1
2.9
—
—
—
0
0
633
5625
1.22
3.40
7.2
5.5
0.0
0.0
estimate
0.36
205
1032
17
64
2.68
3.40
1.6
1.3
—
—
—
0
0
17
64
2.68
3.40
1.6
1.3
—
—
—
0
0
10
27
3.72
3.35
3.7
1.9
—
—
—
0
0
8
14
5.74
3.34
1.0
1.4
—
—
—
0
0
632
5631
1.21
3.27
5.5
4.0
0.0
0.0
estimate
0.00
206
1031
21
90
2.35
3.25
1.0
1.1
—
—
—
0
0
11
33
3.35
3.19
2.0
1.3
9.5
9.2
ug/l
0.11
11
33
1161
12167
0.80
3.18
56.7
24.3
129.9
132.5
g/l
5.44
1141
11917
1161
12167
0.80
3.18
55.9
24.2
7.5
6.9
e9/l
6.99
1129
11739
638
5703
1.21
3.16
5.6
4.1
0.0
0.0
estimate
0.50
201
1018
15
55
2.74
3.16
1.1
1.1
28.3
25.6
u/l
—
9
39
1161
12163
0.80
3.13
55.8
24.2
4.4
4.4
e12/l
0.07
1128
11738
1161
12159
0.80
3.09
55.9
24.2
238.0
242.2
e9/l
1.06
1134
11771
22
99
2.24
3.07
1.7
1.8
—
—
—
0
0
34
181
1.90
3.06
1.1
1.3
164.5
225.2
miu/ml
—
6
78
199
2496
0.77
3.06
2.8
3.2
0.9
0.8
ug/l
0.32
126
1743
7
12
5.85
3.02
2.6
2.0
—
—
—
0
0
332
2789
1.24
3.02
1.8
1.8
25641479.3
16190057.0
pmol/l
0.14
273
2236
33
175
1.91
3.01
1.1
1.1
—
—
—
0
0
19
81
2.36
2.99
2.5
1.8
—
—
—
0
0
297
3533
0.80
2.93
3.7
4.7
21.3
21.7
%
0.16
129
1815
265
2192
1.25
2.75
1.3
1.3
2.8
1.5
u/ml
0.31
58
536
238
2881
0.79
2.73
1.6
1.6
1.5
1.3
mmol/l
2.25
198
2384
30
161
1.88
2.67
1.5
2.2
913.3
2565.7
u/l
—
10
65
7
15
4.68
2.60
1.1
1.1
—
—
—
0
0
11
38
2.91
2.58
1.0
1.2
178.8
180.8
iu/ml
0.01
11
38
22
108
2.05
2.52
1.5
1.4
19.0
27.6
%
0.78
17
67
7
16
4.39
2.47
7.9
11.8
5.6
6.0
mmol/l
—
7
16
7
17
4.13
2.36
1.0
1.1
—
—
—
0
0
24
126
1.92
2.31
4.3
4.0
54.8
56.4
%
0.11
16
85
10
35
2.87
2.30
5.2
3.1
—
—
—
0
0
981
10345
0.85
2.28
7.4
6.4
42.9
40.8
mmol/mol
4.13
917
9368
15
67
2.25
2.18
6.5
3.8
—
—
—
0
0
6
14
4.30
2.15
1.8
1.6
—
—
—
0
0
299
2573
1.20
2.12
3.3
3.0
2.5
2.5
mmol/l
1.21
250
2248
390
4397
0.85
2.11
4.2
5.4
2.5
4.7
ug/l
1.45
324
3873
12
50
2.41
2.02
5.9
3.6
238.2
219.3
u/l
0.33
12
50
968
10178
0.86
2.00
4.6
4.1
1.3
1.3
mmol/l
0.64
887
9036
36
558
0.64
1.96
2.0
1.8
—
—
—
0
0
5
11
4.56
1.94
1.0
1.1
—
—
—
0
0
165
1350
1.25
1.92
2.4
3.9
23.9
24.8
ug/l
0.02
124
1133
6
17
3.54
1.84
1.0
1.1
—
—
—
0
0
64
462
1.40
1.81
1.3
1.3
—
—
—
0
0
24
138
1.75
1.80
1.0
1.1
4.7
34.5
iu/ml
—
7
24
52
363
1.45
1.76
1.4
1.4
245.7
285.8
ug/g
0.83
35
223
8
30
2.68
1.72
1.0
1.4
—
—
—
0
0
1132
11717
0.86
1.67
47.8
19.4
98.2
82.6
umol/l
17.81
1132
11711
8
32
2.51
1.59
1.0
2.1
16.4
14.9
pmol/l
—
8
22
24
144
1.68
1.58
1.8
1.6
67.7
66.7
%
0.05
18
94
17
92
1.86
1.56
1.4
1.1
1.9
1.5
nmol/l
0.68
12
76
470
4291
1.14
1.54
6.1
4.4
—
—
—
0
0
15
78
1.93
1.54
3.7
4.8
267.8
26.8
u/ml
—
5
22
25
153
1.64
1.53
2.3
2.2
5.1
31.8
u/ml
0.53
25
146
42
291
1.46
1.51
1.2
1.2
—
—
—
0
0
19
108
1.77
1.51
1.2
1.4
24617.7
173702.2
e6/l
0.96
13
76
48
660
0.72
1.47
2.7
2.5
—
20.9
—
0
21
42
584
0.71
1.39
1.5
1.4
—
55.3
—
0
25
46
333
1.39
1.34
1.5
1.4
—
—
—
0
0
5
18
2.78
1.28
1.2
1.5
125.8
122.2
ng/l
—
5
18
22
138
1.60
1.26
1.7
1.4
—
—
—
0
0
6
25
2.41
1.24
1.0
1.4
—
—
—
0
0
5
19
2.64
1.21
1.2
1.2
—
—
—
0
0
99
1199
0.81
1.20
1.3
1.4
—
—
—
0
0
62
480
1.30
1.20
2.0
3.1
2001.3
6379.2
u/ml
0.35
49
411
6
26
2.31
1.18
1.2
1.2
—
—
—
0
0
14
237
0.59
1.18
1.6
1.6
—
—
—
0
0
20
125
1.61
1.18
1.1
1.1
—
—
—
0
0
606
5698
1.11
1.15
3.1
2.6
—
—
—
0
0
47
616
0.76
1.11
1.9
1.9
—
—
—
0
0
36
260
1.39
1.10
1.3
1.4
—
—
—
0
0
11
59
1.87
1.07
1.1
1.5
1.0
0.9
g/l
0.22
11
59
5
22
2.28
1.03
1.6
2.0
1.2
1.2
mmol/l
—
5
22
23
160
1.44
0.89
1.4
1.5
—
—
—
0
0
1144
11165
1.10
0.88
40.9
16.5
23.1
27.1
mg/l
5.59
1090
9061
7
127
0.55
0.88
1.1
1.4
—
—
—
0
0
7
127
0.55
0.88
1.1
1.5
—
—
—
0
0
7
127
0.55
0.88
1.1
1.4
—
—
—
0
0
7
127
0.55
0.88
1.1
1.5
—
—
—
0
0
61
747
0.81
0.87
2.0
2.2
13.4
12.3
nmol/l
0.44
53
639
865
8343
1.09
0.86
4.9
3.9
15.8
15.0
pmol/l
12.22
792
7368
1143
11686
0.91
0.85
21.3
10.7
24.0
24.6
u/l
0.64
1111
11160
6
31
1.94
0.84
1.3
1.0
1383.3
1668.4
miu/ml
—
6
31
31
231
1.35
0.83
1.4
1.4
—
—
—
0
0
8
139
0.57
0.83
1.3
1.5
—
—
—
0
0
10
59
1.70
0.76
1.1
1.2
134.6
413.3
u/l
—
10
53
12
185
0.65
0.75
1.6
1.4
—
—
—
0
0
22
158
1.40
0.74
1.4
1.4
—
—
—
0
0
9
54
1.67
0.74
1.2
1.0
—
—
—
0
0
31
237
1.31
0.72
1.1
1.1
—
—
—
0
0
9
57
1.58
0.71
1.2
1.2
—
—
—
0
0
22
160
1.38
0.70
1.4
1.4
—
—
—
0
0
22
160
1.38
0.70
1.4
1.4
—
—
—
0
0
134
1500
0.88
0.69
4.2
4.8
34.3
33.5
%
0.31
96
955
22
161
1.37
0.68
1.4
1.4
—
—
—
0
0
5
29
1.73
0.64
1.0
1.2
—
—
—
0
0
921
8966
1.07
0.63
48.1
19.9
15.2
13.9
%
63.34
899
8735
10
63
1.59
0.62
2.4
1.7
—
—
—
0
0
127
1140
1.12
0.60
1.6
2.1
229.0
148.1
ug/g
0.63
109
881
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
16
221
0.72
0.60
1.6
1.8
61.0
41.5
nmol/l
1.50
16
204
12
80
1.50
0.60
2.3
2.5
—
—
—
0
0
20
148
1.36
0.59
1.1
1.1
—
14.3
—
0
8
15
106
1.42
0.57
1.3
1.3
—
—
—
0
0
21
159
1.33
0.55
1.4
1.4
—
—
—
0
0
22
168
1.31
0.55
3.0
2.6
11.3
25.7
mg/l
—
6
42
11
74
1.49
0.53
1.5
1.2
—
—
—
0
0
11
156
0.70
0.50
1.1
1.5
—
—
—
0
0
7
46
1.52
0.48
1.1
1.3
—
—
—
0
0
34
281
1.21
0.47
9.5
3.8
30.6
29.9
mg/l
0.04
28
182
1034
10152
1.06
0.47
6.3
4.8
2.2
2.1
mu/l
0.25
950
9042
6
94
0.64
0.42
1.2
1.6
—
—
—
0
0
8
57
1.41
0.42
3.6
2.4
14.1
13.1
%
—
8
57
125
1357
0.91
0.42
1.5
1.4
—
—
—
0
0
8
58
1.38
0.41
1.1
1.0
—
—
—
0
0
5
33
1.52
0.41
1.2
1.2
—
—
—
0
0
33
282
1.17
0.35
1.5
1.7
31549.2
15914.9
e6/l
0.59
26
202
1157
11698
0.95
0.33
52.2
19.9
4.0
4.0
mmol/l
2.64
1128
11339
1156
11680
0.96
0.30
52.0
19.7
139.0
139.6
mmol/l
9.13
1130
11333
19
228
0.83
0.29
2.1
1.7
—
—
—
0
0
7
56
1.25
0.29
1.4
1.1
—
—
—
0
0
20
237
0.84
0.27
1.4
1.3
61.2
48.5
e6/l
0.08
15
188
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
8
64
1.25
0.27
1.3
1.2
—
—
—
0
0
14
114
1.23
0.25
1.3
1.1
0.6
2.6
u/ml
—
8
51
25
287
0.87
0.24
2.0
1.8
—
—
—
0
0
25
217
1.15
0.24
1.5
1.3
—
—
—
0
0
5
41
1.22
0.22
1.2
1.0
—
—
—
0
0
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
22
191
1.15
0.22
1.2
1.3
19.5
9.6
u/l
1.58
16
146
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
11
89
1.24
0.21
1.3
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
51
1.18
0.19
1.3
1.1
—
—
—
0
0
6
51
1.18
0.19
1.5
1.2
—
—
—
0
0
1024
10328
0.97
0.18
37.0
15.5
66.8
73.8
ml/min/173m2
15.34
921
8539
17
193
0.88
0.15
1.4
1.4
34.6
24.1
iu/l
0.52
12
160
246
2522
0.97
0.15
6.1
4.5
1.0
1.0
kg/l
0.05
40
398
26
286
0.91
0.15
2.5
1.7
—
—
—
0
0
14
121
1.16
0.15
3.7
2.0
0.5
2.2
u/field
—
6
34
155
1598
0.97
0.13
13.1
8.4
—
—
—
0
0
11
96
1.15
0.10
1.4
1.1
—
—
—
0
0
5
44
1.14
0.10
1.2
1.3
—
—
—
0
0
7
66
1.06
0.08
1.0
1.2
—
—
—
0
0
7
67
1.04
0.08
1.0
1.2
—
—
—
0
0
13
118
1.10
0.07
1.0
1.0
—
1.8
—
0
38
27
257
1.05
0.05
1.1
1.1
—
8.3
—
0
22
975
9764
1.00
0.02
42.8
18.2
38.1
38.6
%
0.62
617
6197
30
297
1.01
0.00
1.8
1.5
—
—
—
0
0
46
457
1.01
0.00
1.1
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
15
150
1.00
0.00
2.1
1.5
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint I9_SECONDRIGHT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_SECONDRIGHT | 4.26 [3.59, 5.05] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.015 |
During the follow-up period (1.1.1998 — 31.12.2019), 1966 out of 3567 females with I9_SECONDRIGHT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_SECONDRIGHT | 5.409 [4.32, 6.77] | < 0.001 |
| Birth year | 0.983 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 1936 out of 3007 males with I9_SECONDRIGHT died.
Mortality risk
Mortality risk for people of age
years, who have I9_SECONDRIGHT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.316% | 0.847% |
| 5 | 2.129% | 5.453% |
| 10 | 4.79% | 12.918% |
| 15 | 10.15% | 23.045% |
| 20 | 17.095% | 36.926% |
Relationships between endpoints
↥Index endpoint: I9_SECONDRIGHT – Secondary right heart disease
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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