This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Erectile dysfunction, exclusion
ERECTILE_EXCLUSION
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly males |
226837 |
2. Check conditionsNone |
226837 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
131 |
4. Check minimum number of eventsNone |
131 |
5. Include endpointsNone |
131 |
6. Filter based on genotype QC (FinnGen only) |
131 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- I27
- Name in latin
- Hypertensio pulmonalis primaria
Similar endpoints
↥List of similar endpoints to
Erectile dysfunction, exclusion
based on the number of shared cases.
Similar with more cases:
- Secondary right heart disease
- Other pulmonary heart/vessel disease
- Pulmonary heart disease, diseases of pulmonary circulation
- Cardiovascular diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 131 | - | 131 |
| Unadjusted period prevalence (%) | 0.06 | - | 0.06 |
| Median age at first event (years) | 66.15 | - | 66.15 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 123
- Matched controls
- 1230
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I27.0
ICD-10 Finland
Primary pulmonary hypertension
+∞
110.7
89
*
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
72.0
38.8
43
9
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
104.3
35.1
37
5
4168X
ICD-9 Finland
Chronic pulmonary heart disease, Other chronic pulmonary heart diseases
+∞
32.8
30
*
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
148.5
32.5
33
*
G04BE03
ATC
sildenafil; oral
48.0
29.4
35
10
C03CA01
ATC
furosemide; systemic
8.8
26.9
91
300
C03DA01
ATC
spironolactone; oral
11.9
26.1
53
73
I27.8
ICD-10 Finland
Other specified pulmonary heart diseases
132.5
21.3
22
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
12.6
21.3
40
45
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
7.6
20.8
58
129
R06.0
ICD-10 Finland
Dyspnoea
5.6
15.1
53
147
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
11.6
14.4
27
29
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
15.4
14.1
23
18
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
4.9
14.0
57
184
C02KX04
ATC
macitentan; oral
+∞
13.8
13
*
B01AA03
ATC
warfarin; systemic
4.4
12.8
59
211
C02KX01
ATC
bosentan; oral
+∞
12.7
12
*
I50.9
ICD-10 Finland
Heart failure, unspecified
4.7
11.8
46
137
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.7
10.8
41
118
J96.1
ICD-10 Finland
Chronic respiratory failure
13.8
10.7
18
15
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
4.1
10.7
49
169
WX740
NOMESCO Finland
Nitrogen oxide therapy
+∞
10.6
10
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.4
9.8
71
349
I26.0
ICD-10 Finland
Pulmonary embolism with mention of acute cor pulmonale
16.8
9.8
15
10
4289X
ICD-9 Finland
Heart failure, unspecified
23.9
9.6
13
6
C01AA05
ATC
digoxin; systemic
4.3
9.1
37
112
201
Kela drug reimbursment
Chronic cardiac insufficiency
5.3
9.0
28
64
H02AB06
ATC
prednisolone; systemic
3.2
8.9
75
400
XF620
NOMESCO Finland
Examination of circulation with color method
+∞
8.4
8
*
I50.0
ICD-10 Finland
Congestive heart failure
5.2
8.3
26
60
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
14.3
8.1
13
10
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
14.3
8.1
13
10
TPH04
NOMESCO Finland
Cathetrisation of vein
3.5
7.9
43
165
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
5.6
7.6
22
46
AP2
HP
Catheterization of the right side of the heart
32.0
7.2
9
*
A12BA01
ATC
potassium chloride; oral
8.4
7.1
15
20
A46
ICD-10 Finland
Erysipelas
3.5
6.8
33
115
WX872
NOMESCO Finland
Intensive care
6.9
6.7
16
26
R03AC02
ATC
salbutamol; inhalant
2.7
6.4
68
390
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
6.4
6.4
16
28
ZX108
NOMESCO Finland
Inhalation
19.2
6.4
9
5
XF400
NOMESCO Finland
ECG with 12 standard connections
3.1
6.3
38
154
XF622
NOMESCO Finland
Measurement of minute volume of heart
28.2
6.3
8
*
R4110
NOMESCO Finland
Physiotherapy
3.0
6.3
41
176
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
49
132
5.33
18.10
5.0
2.4
17.4
23.7
%
2.35
43
119
49
136
5.16
17.40
5.0
2.4
2.5
2.3
g/l
1.91
49
126
39
112
4.53
12.90
15.1
13.5
1.3
0.5
mmol/l
0.32
26
93
17
9
21.44
11.95
1.5
1.4
—
—
—
0
0
11
12
9.92
9.11
11.2
11.6
11.5
9.7
mg/l
0.56
11
12
29
88
3.95
8.69
2.8
2.9
0.2
0.2
g/l
1.13
29
79
30
96
3.76
8.32
9.0
6.0
2.1
0.6
mmol/l
0.90
25
65
25
73
4.00
7.86
22.0
9.6
25.3
24.4
mmol/l
0.38
25
73
29
98
3.52
7.37
9.3
6.0
6.0
5.6
kpa
0.85
29
92
31
111
3.35
7.20
3.0
1.8
—
—
—
0
0
59
303
2.72
7.19
9.8
3.2
28.3
34.9
u/l
1.68
59
290
15
31
5.34
7.12
2.5
2.6
—
—
—
0
0
30
114
3.12
6.27
3.2
1.9
—
—
—
0
0
11
19
6.23
6.22
2.8
1.4
—
—
—
0
0
11
20
5.91
5.91
2.1
2.0
—
—
—
0
0
38
176
2.63
5.48
19.4
1.6
1.7
2.3
mg/l
0.39
30
143
72
448
2.35
5.42
22.1
6.9
15.7
12.7
umol/l
1.33
72
435
61
365
2.26
4.91
6.7
4.2
332.1
59.4
ng/l
0.42
53
266
8
8
10.55
4.58
1.0
1.0
—
—
—
0
0
24
96
2.84
4.53
1.2
1.2
36.6
33.9
iu/ml
—
5
29
32
152
2.46
4.30
3.2
2.0
—
—
—
0
0
13
39
3.59
3.87
1.3
1.5
—
—
—
0
0
20
79
2.81
3.85
8.1
3.3
5.0
5.0
kpa
0.08
20
74
19
75
2.79
3.66
2.4
1.5
—
—
—
0
0
61
408
1.93
3.32
21.2
9.4
1.2
1.2
mmol/l
2.05
53
355
10
28
3.78
3.26
2.3
1.4
—
—
—
0
0
8
15
5.60
3.24
1.1
1.5
—
—
—
0
0
57
376
1.91
3.21
18.9
8.2
1.2
1.2
mmol/l
3.34
52
343
15
57
2.84
3.09
2.7
1.4
—
—
—
0
0
5
5
10.32
3.00
1.4
1.4
96.6
75.8
%
—
5
5
70
505
1.83
2.90
14.6
10.3
4.7
4.3
e9/l
0.55
63
440
5
6
8.60
2.77
2.0
1.7
208.8
133.7
u/l
—
5
6
14
55
2.73
2.72
9.4
3.9
24.8
24.9
mmol/l
0.06
14
55
6
12
5.18
2.43
3.0
1.5
—
—
—
0
0
7
18
4.05
2.28
1.6
1.2
—
—
—
0
0
7
19
3.83
2.18
1.0
1.1
—
—
—
0
0
8
25
3.34
2.13
3.5
1.6
—
—
—
0
0
8
25
3.34
2.13
1.5
1.4
—
—
—
0
0
38
248
1.75
2.08
4.0
2.3
147.8
300.4
u/l
1.24
38
236
34
496
0.58
2.03
3.1
4.6
19.0
21.4
%
0.55
14
238
7
21
3.46
1.99
2.6
1.3
—
—
—
0
0
5
11
4.68
1.96
1.0
1.3
—
—
—
0
0
38
257
1.67
1.82
5.0
2.9
0.2
0.4
e6/l
0.48
31
194
6
146
0.38
1.78
2.2
2.1
9.4
14.2
nmol/l
—
6
134
6
18
3.44
1.77
1.0
1.4
—
—
—
0
0
6
18
3.44
1.77
2.7
1.3
—
—
—
0
0
6
18
3.44
1.77
1.0
1.4
—
—
—
0
0
5
13
3.95
1.73
2.2
2.0
—
—
—
0
0
7
25
2.90
1.67
3.9
1.6
—
—
—
0
0
5
14
3.67
1.63
3.8
1.2
—
—
—
0
0
5
15
3.42
1.54
2.2
1.9
—
—
—
0
0
45
330
1.55
1.53
4.5
3.1
—
—
—
0
0
5
17
3.01
1.37
4.4
1.8
—
—
—
0
0
5
17
3.01
1.37
2.4
3.4
—
—
—
0
0
0
40
0.00
1.35
0.0
1.6
—
244.6
—
0
35
16
92
1.84
1.32
2.3
2.4
11.8
11.1
ug/l
0.04
16
83
5
18
2.85
1.29
1.2
1.2
201.8
226.2
u/ml
—
5
6
5
18
2.85
1.29
1.2
1.3
—
—
—
0
0
24
157
1.65
1.29
3.3
2.8
0.4
0.4
e6/l
0.03
12
90
49
610
0.69
1.26
3.9
5.1
2.1
2.9
ug/l
0.45
43
543
27
370
0.66
1.11
2.4
3.2
0.6
0.8
ug/l
1.03
17
243
5
21
2.43
1.10
1.0
1.2
—
—
—
0
0
37
283
1.43
0.99
3.5
2.7
50.7
55.6
u/l
0.45
37
267
15
93
1.69
0.99
4.1
2.9
—
—
—
0
0
23
160
1.53
0.97
3.2
2.7
0.3
0.6
e6/l
0.58
11
92
69
787
0.74
0.92
4.5
4.7
6.2
6.2
mmol/l
0.10
62
712
13
83
1.63
0.78
1.2
1.2
64.5
14.1
u/ml
—
6
28
5
24
2.12
0.75
1.2
1.2
—
—
—
0
0
38
306
1.34
0.74
2.4
2.1
73.2
87.2
pmol/l
1.85
26
182
9
57
1.62
0.73
4.0
1.9
—
—
—
0
0
5
32
1.58
0.42
2.4
1.2
—
—
—
0
0
45
397
1.20
0.41
4.8
3.4
0.0
0.0
estimate
0.00
14
76
8
115
0.68
0.39
1.5
1.4
—
—
—
0
0
44
394
1.18
0.33
6.5
4.5
0.0
0.0
estimate
0.00
15
74
45
406
1.17
0.31
4.7
3.4
0.0
0.0
estimate
0.00
15
70
40
360
1.16
0.28
7.1
4.6
—
—
—
0
0
25
219
1.17
0.24
5.1
3.7
0.0
0.0
estimate
0.49
14
68
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
34
313
1.12
0.17
4.9
3.7
—
—
—
0
0
22
199
1.13
0.14
4.5
2.8
—
—
—
0
0
16
145
1.12
0.10
3.4
3.1
2.4
2.5
mmol/l
0.06
11
126
9
84
1.08
0.07
11.2
9.2
—
—
—
0
0
75
766
0.95
0.07
44.4
14.7
72.7
79.4
ml/min/173m2
1.49
69
637
48
489
0.97
0.02
3.5
3.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
7.6
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
10.7
—
0
7
0
5
0.00
0.00
0.0
3.0
—
35.8
—
0
5
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
12.8
—
0
6
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: ERECTILE_EXCLUSION – Erectile dysfunction, exclusion
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).