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Lung transplant status

Endpoint Browser PheWeb

Z21_LUNG_TRANSPLANT_STATUS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — Z94.2
  • Cause of death: ICD-10 — Z94.2

2 out of 7 registries used, show all original rules.

250

4. Check minimum number of events

None

250

5. Include endpoints

None

250

6. Filter based on genotype QC (FinnGen only)

250

Control definitions (FinnGen only)

Control exclude
LUNG_TRANSPLANTATION

Extra metadata

First used in FinnGen datafreeze
DF5

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 624 258 366
Only index persons 563 236 327
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population - 54.70 58.10
Only index persons 56.77 54.70 58.26

-FinnGen-

Key figures

All Female Male
Number of individuals 250 102 148
Unadjusted period prevalence (%) 0.05 0.03 0.07
Median age at first event (years) 57.14 54.70 58.83

-FinRegistry-

Age distribution of first events

0102030405060708090020406080100120140160AgeIndividuals

-FinnGen-

Age distribution of first events

01020304050607080900102030405060708090AgeIndividuals

-FinRegistry-

Year distribution of first events

197019751980198519901995200020052010201520202022020406080100120140160180YearIndividuals

-FinnGen-

Year distribution of first events

1970197519801985199019952005201020152020202301020304050607080YearIndividuals

-FinRegistry-

Cumulative Incidence Function

01020304050607080901000.00.10.20.30.40.50.60.70.80.91.0AgeProbability of first incidence (%)

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
222
Matched controls
2220
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Z94.2
ICD-10 Finland
Lung transplant status
+∞
321.5
222
*
127
Kela drug reimbursment
Transplant complication
1132.0
242.1
199
17
L04AA06
ATC
mycophenolic acid; systemic
666.8
218.2
186
17
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
7168.3
214.6
171
*
GDG10
NOMESCO Finland
Bilateral transplantation of lung
+∞
199.2
160
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
135.7
161.5
166
47
UGC12
NOMESCO Finland
Flexible bronchoscopy
111.1
156.7
168
60
TGC00
NOMESCO Finland
Bronchial lavation
140.0
138.0
139
26
L04AD01
ATC
ciclosporin; systemic
144.2
133.6
134
23
GD1AD
NOMESCO Finland
Thorax CT examination
94.6
130.2
140
39
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
78.2
129.8
146
53
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
590.4
127.6
115
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
40.2
117.1
182
225
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
143.7
116.3
117
17
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
52.5
116.2
144
75
GD1BT
NOMESCO Finland
Biopsy of lung with X-ray guidance
+∞
112.3
98
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
68.8
111.5
127
42
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
380.7
110.8
103
5
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
45.7
109.9
141
81
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
246.3
109.7
105
8
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
37.7
106.1
196
369
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
47.3
103.1
129
63
R4110
NOMESCO Finland
Physiotherapy
35.6
100.7
198
417
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
83.1
97.1
106
24
C08CA02
ATC
felodipine; oral
32.1
89.7
126
87
GD1AA
NOMESCO Finland
Thorax X-ray examination
50.8
88.4
212
653
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
44.4
83.5
104
43
XX4BW
NOMESCO Finland
NA
594.3
82.8
77
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
20.3
81.6
145
188
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
18.9
79.5
148
212
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
27.4
79.3
116
85
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
18.0
78.9
173
363
WX872
NOMESCO Finland
Intensive care
34.5
78.5
105
56
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
59.5
77.7
90
25
ZX108
NOMESCO Finland
Inhalation
269.8
75.3
73
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
27.8
68.3
97
60
WX404
NOMESCO Finland
Intravenous generell anesthesy
14.3
68.1
149
277
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
78.5
67.1
74
14
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
99.2
64.7
69
10
H02AB06
ATC
prednisolone; systemic
16.5
61.8
197
717
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
19.2
61.5
101
92
J18.9
ICD-10 Finland
Pneumonia, unspecified
12.4
60.9
139
263
C10AA03
ATC
pravastatin; oral
25.3
60.5
88
56
C03CA01
ATC
furosemide; systemic
12.2
59.4
135
250
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
139.1
59.3
61
6
WX408
NOMESCO Finland
General anesthesy, balanced
11.1
57.9
159
412
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
11.7
57.4
133
251
A07AA02
ATC
nystatin; oral
26.7
55.1
78
44
5AB14
NOMESCO Finland
NA
219.3
51.3
51
*
ZX120
NOMESCO Finland
Intravenous
14.5
51.2
95
109
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
+∞
51.0
47
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
16.1
50.5
88
87
ZXA10
NOMESCO Finland
Bilateral
11.0
50.4
114
194
J96.1
ICD-10 Finland
Chronic respiratory failure
88.5
49.8
54
8
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
72.5
49.2
55
10
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
22.1
48.5
73
48
L04AX01
ATC
azathioprine; systemic
18.8
45.1
72
55
GD1RA
NOMESCO Finland
Dynamic X-ray examination of respiratory organs with convetional X-ray picture
187.0
44.6
45
*
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
22.0
42.9
64
40
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
12.2
40.1
79
96
J01MA14
ATC
moxifloxacin; systemic
12.0
39.3
78
96
284
Kela drug reimbursment
Nintedanib and pirfenidone
436.6
38.2
37
*
RS123
NOMESCO Finland
NA
+∞
36.5
34
*
XG410
NOMESCO Finland
Flow-volume spirometry
19.8
36.4
56
37
JN4BD
NOMESCO Finland
Extensive body CT
9.9
36.3
81
122
C10AA01
ATC
simvastatin; oral
6.3
35.7
151
562
2AX04
NOMESCO Finland
NA
206.6
34.8
35
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
6.6
34.3
113
302
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
48.3
33.5
40
10
L04AX05
ATC
pirfenidone; oral
+∞
33.2
31
*
C07AB07
ATC
bisoprolol; oral
5.7
31.9
156
652
5BA08
NOMESCO Finland
NA
99.9
31.7
34
*
TK800
NOMESCO Finland
Hemodialysis
24.2
31.6
45
23
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
7.6
31.6
85
168
R03AC02
ATC
salbutamol; inhalant
6.0
31.5
171
799
C09AA05
ATC
ramipril; oral
6.1
31.4
109
303
TPH04
NOMESCO Finland
Cathetrisation of vein
6.3
31.2
102
262
XG466
NOMESCO Finland
Sleep oxymetry
18.2
31.1
49
34
3A006
NOMESCO Finland
NA
+∞
31.0
29
*
Z94.0
ICD-10 Finland
Kidney transplant status
36.0
30.7
39
13
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
10.5
29.9
62
79
356
Kela drug reimbursment
Nintedanib and pirfenidone
333.3
29.5
29
*
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
26.8
29.1
40
18
L04AA01
ATC
[U] ciclosporin; systemic
38.7
28.8
36
11
R4190
NOMESCO Finland
Nutritional therapy
13.0
28.5
52
51
R06.0
ICD-10 Finland
Dyspnoea
5.8
28.4
100
275
WX892
NOMESCO Finland
Monitored bed care
10.4
28.0
58
73
WX402
NOMESCO Finland
General anaesthesia
5.9
27.9
94
244
M05BA04
ATC
alendronic acid; oral
14.0
27.9
49
44
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
13.4
27.9
50
47
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
26.7
27.6
38
17
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
5.2
27.4
170
854
R03BB04
ATC
tiotropium bromide; inhalant
8.6
27.2
64
100
A02BA03
ATC
famotidine; systemic
15.0
27.1
46
38
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
22.2
26.8
39
21
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
292.9
26.3
26
*
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
25.0
25.8
36
17
TPH07
NOMESCO Finland
Cathetrisation of artery
7.4
25.7
67
122
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
44.7
25.6
31
8
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
9.9
25.5
54
70
WX740
NOMESCO Finland
Nitrogen oxide therapy
280.2
25.2
25
*
ZX197
NOMESCO Finland
NA
146.5
25.2
26
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
7.0
25.1
69
135
R50.9
ICD-10 Finland
Fever, unspecified
6.3
25.0
76
170
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
10.0
24.8
52
66
Z94.1
ICD-10 Finland
Heart transplant status
76.4
24.4
27
*
1CX01
NOMESCO Finland
NA
267.7
24.1
24
*
ZXA00
NOMESCO Finland
Right side
4.8
24.1
102
332
XJC10
NOMESCO Finland
Oesophageal pH monitoring
53.1
23.9
28
6
B01AB04
ATC
dalteparin; parenteral
16.1
23.9
39
29
A11CC03
ATC
alfacalcidol; systemic
25.6
23.8
33
15
AN1
HP
Coronary angiography
7.5
23.8
61
107
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
7.6
23.8
60
103
J01MA12
ATC
levofloxacin; systemic
5.5
23.7
82
213
XX4AW
NOMESCO Finland
NA
73.2
23.4
26
*
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
12.4
23.4
43
42
R03AK07
ATC
formoterol and budesonide; inhalant
5.1
23.0
87
249
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
4.2
22.6
145
685
ZX100
NOMESCO Finland
Oral
25.5
22.4
31
14
AK3
HP
BLTX (both lung transplants)
+∞
22.3
21
*
RS221
NOMESCO Finland
NA
24.5
21.5
30
14
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
8.0
21.3
51
80
137
Kela drug reimbursment
Uraemia requiring dialysis
33.9
21.1
27
9
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
6.8
21.0
57
107
J43.9
ICD-10 Finland
Emphysema, unspecified
63.7
20.3
23
*
N18.8
ICD-10 Finland
Other chronic renal failure
20.2
20.2
30
17
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
14.7
20.2
34
27
RD210
NOMESCO Finland
NA
16.8
20.1
32
22
FXD00
NOMESCO Finland
Use of ECHLA without concurrent surgical procedure
218.7
19.9
20
*
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
16.1
19.8
32
23
XF400
NOMESCO Finland
ECG with 12 standard connections
4.8
19.7
76
216
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
4.6
19.5
79
236
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.0
19.2
71
192
B05DA
ATC
Isotonic solutions
31.1
19.2
25
9
Z49.2
ICD-10 Finland
Other dialysis
31.1
19.2
25
9
Z94.3
ICD-10 Finland
Heart and lungs transplant status
+∞
19.0
18
*
N02AX02
ATC
tramadol; systemic, rectal
3.7
19.0
134
650
J93.1
ICD-10 Finland
Other spontaneous pneumothorax
206.7
18.8
19
*
E88.0
ICD-10 Finland
Disorders of plasma-protein metabolism, not elsewhere classified
206.7
18.8
19
*
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
33.4
18.8
24
8
R03AK06
ATC
salmeterol and fluticasone; inhalant
5.4
18.4
61
146
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
16.5
18.2
29
20
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
6.1
18.2
53
108
TDM10
NOMESCO Finland
Puncture of maxillary antrum
11.6
18.2
34
34
J01GB01
ATC
tobramycin; inhalant, parenteral
194.9
17.8
18
*
GBB00
NOMESCO Finland
Tracheostomy
26.7
17.7
24
10
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
11.9
17.4
32
31
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
9.6
17.3
36
44
J01FA10
ATC
azithromycin; systemic
3.8
17.3
170
1033
RS230
NOMESCO Finland
NA
24.3
17.3
24
11
R52.0
ICD-10 Finland
Acute pain
15.1
17.0
28
21
B01AA03
ATC
warfarin; systemic
4.7
16.9
65
181
N02AA05
ATC
oxycodone; systemic
5.7
16.9
52
113
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
97.5
16.8
18
*
XJC02
NOMESCO Finland
Mesurement of oesophageal pressure and pressure profile of lower oesophageal sphincter
97.5
16.8
18
*
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
183.2
16.7
17
*
JN4AD
NOMESCO Finland
Body CT examination
7.2
16.7
42
70
A02BC05
ATC
esomeprazole; systemic
3.4
16.6
122
585
R03AC13
ATC
formoterol; inhalant
11.4
16.6
31
31
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
12.7
16.3
29
26
C10AX09
ATC
ezetimibe; oral
5.5
16.0
51
115
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
4.3
15.9
67
203
Z94.4
ICD-10 Finland
Liver transplant status
91.7
15.8
17
*
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
171.6
15.7
16
*
E84.0
ICD-10 Finland
Cystic fibrosis with pulmonary manifestations
171.6
15.7
16
*
I27.0
ICD-10 Finland
Primary pulmonary hypertension
171.6
15.7
16
*
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
41.3
15.7
19
5
B03XA01
ATC
erythropoietin; parenteral
41.3
15.7
19
5
RK320
NOMESCO Finland
NA
41.3
15.7
19
5
H02AB04
ATC
methylprednisolone; systemic
4.5
15.5
61
172
WW200
NOMESCO Finland
Immunization
11.3
15.5
29
29
TPX10
NOMESCO Finland
Implantation of vascular injection port
11.3
15.5
29
29
B05DB
ATC
Hypertonic solutions
34.4
15.1
19
6
B03XA02
ATC
darbepoetin alfa; parenteral
20.2
15.0
22
12
J01CA04
ATC
amoxicillin; systemic
5.1
15.0
203
1506
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
27.3
15.0
20
8
SAA03
NOMESCO Finland
Extended examination of mouth
3.1
14.8
122
621
T86.8
ICD-10 Finland
Failure and rejection of other transplanted organs and tissues
+∞
14.7
14
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
20.9
14.5
21
11
Z49.1
ICD-10 Finland
Extracorporeal dialysis
20.9
14.5
21
11
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
5.5
14.5
45
98
Z01.8
ICD-10 Finland
Other specified special examinations
3.6
14.3
78
291
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
10.2
14.2
28
31
ZX121
NOMESCO Finland
Central venous catheter
32.4
14.1
18
6
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
5.7
14.1
42
87
B07.9
ICD-10 Finland
Verruca simplex
8.7
13.9
30
39
H26.3
ICD-10 Finland
Drug-induced cataract
36.6
13.7
17
5
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
+∞
13.7
13
*
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
12.7
13.7
24
21
304
Kela drug reimbursment
Dornase alfa
148.7
13.6
14
*
R05CB13
ATC
dornase alfa (desoxyribonuclease); inhalant
148.7
13.6
14
*
AP2
HP
Catheterization of the right side of the heart
148.7
13.6
14
*
WX002
NOMESCO Finland
Sedation and analgesia
3.7
13.5
68
237
Z49.0
ICD-10 Finland
Preparatory care for dialysis
42.9
13.3
16
*
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
18.2
13.3
20
12
SPAT1325
SPAT
Vaccination
3.1
13.0
96
441
R03DA04
ATC
theophylline; systemic, rectal
9.7
12.9
26
30
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
3.8
12.9
60
195
A02BC02
ATC
pantoprazole; systemic
3.0
12.8
163
1060
M81.9
ICD-10 Finland
Osteoporosis, unspecified
14.4
12.7
21
16
A02BC01
ATC
omeprazole; systemic
3.2
12.7
83
348
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
26.1
12.7
17
7
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
26.1
12.7
17
7
3A064
NOMESCO Finland
NA
+∞
12.6
12
*
FXE00
NOMESCO Finland
Use of ECLA
+∞
12.6
12
*
C02KX01
ATC
bosentan; oral
+∞
12.6
12
*
FXF00
NOMESCO Finland
Decannulation after ECHLA or ECLA
+∞
12.6
12
*
E84.9
ICD-10 Finland
Cystic fibrosis, unspecified
137.4
12.6
13
*
J01XB01
ATC
colistin; inhalant, parenteral
137.4
12.6
13
*
RK110
NOMESCO Finland
NA
22.9
12.2
17
8
R03BB01
ATC
ipratropium bromide; inhalant
12.8
12.1
21
18
JN4CD
NOMESCO Finland
Very extensive body CT
8.5
12.0
26
34
A12AA04
ATC
calcium carbonate; oral
15.8
12.0
19
13
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
7.9
12.0
27
38
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
8.9
11.9
25
31
6BA02
NOMESCO Finland
NA
68.7
11.7
13
*
SAA04
NOMESCO Finland
Special inverstigation of mouth
5.7
11.7
34
68
R03AC03
ATC
terbutaline; inhalant
4.1
11.6
48
140
2770A
ICD-9 Finland
Other and unspecified disorders of metabolism, Cystic fibrosis
+∞
11.6
11
*
J02AC03
ATC
voriconazole; systemic
126.3
11.5
12
*
L01XE31
ATC
[U] nintedanib; oral
126.3
11.5
12
*
V03AE02
ATC
sevelamer; oral
126.3
11.5
12
*
B02.9
ICD-10 Finland
Zoster without complication
6.5
11.5
30
52
N18.0
ICD-10 Finland
End-stage renal disease
37.2
11.4
14
*
I50.9
ICD-10 Finland
Heart failure, unspecified
5.3
11.4
35
75
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
12.1
11.3
20
18
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
26.6
11.3
15
6
J45.9
ICD-10 Finland
Asthma, unspecified
3.5
11.3
60
215
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
4.7
11.2
39
96
WX720
NOMESCO Finland
Own respiration
7.9
11.1
25
35
M01AH05
ATC
etoricoxib; oral
0.3
11.1
51
1027
J45.0
ICD-10 Finland
Predominantly allergic asthma
5.0
11.0
36
83
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
4.1
10.9
45
130
TK820
NOMESCO Finland
Peritoneal dialysis
29.7
10.9
14
5
3AC01
NOMESCO Finland
NA
22.8
10.8
15
7
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
22.8
10.8
15
7
N03AX16
ATC
pregabalin; oral
3.0
10.8
75
324
RS220
NOMESCO Finland
NA
12.1
10.8
19
17
R03BA02
ATC
budesonide; inhalant
3.4
10.7
58
210
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
15.2
10.7
17
12
J05AB11
ATC
valaciclovir; oral
3.8
10.6
48
151
R28
ICPC
Limited function/disability (R)
17.1
10.5
16
10
348
Kela drug reimbursment
Roflumilast
115.2
10.5
11
*
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
115.2
10.5
11
*
J43.1
ICD-10 Finland
Panlobular emphysema
+∞
10.5
10
*
R05CB01
ATC
acetylcysteine; inhalant, oral
34.3
10.4
13
*
EBA10
NOMESCO Finland
Surgical removal of tooth
3.7
10.4
49
159
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
20.0
10.4
15
8
N17.8
ICD-10 Finland
Other acute renal failure
24.8
10.4
14
6
G04BE03
ATC
sildenafil; oral
14.0
10.3
17
13
N17.9
ICD-10 Finland
Acute renal failure, unspecified
8.3
10.2
22
29
A09AA02
ATC
multienzymes (lipase, protease etc.)
15.6
10.2
16
11
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
6.7
10.0
25
41
602
Kela drug reimbursment
Children's severe malnutrition
21.2
9.9
14
7
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.5
9.9
49
166
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
5.7
9.8
28
55
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
57.6
9.7
11
*
Z94.9
ICD-10 Finland
Transplanted organ and tissue status, unspecified
57.6
9.7
11
*
JN3AD
NOMESCO Finland
Abdominal CT examination
4.9
9.7
32
74
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
16.0
9.7
15
10
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.9
9.6
41
122
UDH02
NOMESCO Finland
Rhinopharyngoscopy
4.7
9.6
33
80
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
13.2
9.5
16
13
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
31.5
9.5
12
*
E84.8
ICD-10 Finland
Cystic fibrosis with other manifestations
104.3
9.5
10
*
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
104.3
9.5
10
*
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
104.3
9.5
10
*
B01AC11
ATC
iloprost; inhalant, parenteral
+∞
9.4
9
*
J84.0
ICD-10 Finland
Alveolar and parietoalveolar conditions
+∞
9.4
9
*
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
14.5
9.3
15
11
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
19.6
9.0
13
7
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.5
9.0
98
536
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
25.2
9.0
12
5
SPAT1262
SPAT
Handing over of treatment supplies
3.0
8.9
59
242
J01DB01
ATC
cefalexin; oral
3.1
8.9
193
1518
K05.30
ICD-10 Finland
Periodontitis complex
3.4
8.9
46
160
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
5.2
8.8
27
58
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
52.1
8.7
10
*
XJC00
NOMESCO Finland
Oesophageal manometry
52.1
8.7
10
*
GD1LA
NOMESCO Finland
GD
12.3
8.7
15
13
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
17.1
8.7
13
8
J47
ICD-10 Finland
Bronchiectasis
17.1
8.7
13
8
TK810
NOMESCO Finland
Hemofiltration
17.1
8.7
13
8
V03AE01
ATC
polystyrene sulfonate; oral
17.1
8.7
13
8
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
4.3
8.6
32
84
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
28.8
8.6
11
*
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
13.5
8.5
14
11
L57.0
ICD-10 Finland
Actinic keratosis
4.6
8.5
29
70
E84.1
ICD-10 Finland
Cystic fibrosis with intestinal manifestations
93.5
8.5
9
*
GX1K5
NOMESCO Finland
Diffusion capacity
93.5
8.5
9
*
V03AG01
ATC
sodium cellulose phosphate; systemic
93.5
8.5
9
*
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
7.0
8.4
20
31
XW000
NOMESCO Finland
Bone marrow biopsy
6.5
8.4
21
35
L04AA05
ATC
[U] tacrolimus; systemic
+∞
8.4
8
*
JD1FN
NOMESCO Finland
Scintigraphy of gastric function
+∞
8.4
8
*
WX721
NOMESCO Finland
Oxygen concentrator therapy
+∞
8.4
8
*
XG467
NOMESCO Finland
Nocturnal CO2 monitoring
+∞
8.4
8
*
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.5
8.4
81
415
D70.82
ICD-10 Finland
Drug-induced neutropenia
12.4
8.2
14
12
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.3
8.2
115
707
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
18.0
8.2
12
7
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.8
8.1
58
249
HA1AA
NOMESCO Finland
X-ray mammography
5.1
8.1
25
54
K06.18
ICD-10 Finland
Another gingival hyperplasia
23.0
8.1
11
5
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
3.2
8.1
45
165
ZXA05
NOMESCO Finland
Left side
2.6
8.0
65
302
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
13.7
8.0
13
10
J45.1
ICD-10 Finland
Nonallergic asthma
4.2
8.0
30
80
J01AA02
ATC
doxycycline; systemic
2.6
8.0
180
1386
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
5.7
7.9
22
42
K65.0
ICD-10 Finland
Acute peritonitis
15.8
7.8
12
8
RS310
NOMESCO Finland
NA
46.6
7.8
9
*
B01AB10
ATC
tinzaparin; parenteral
4.8
7.7
25
57
H02AB09
ATC
hydrocortisone; systemic
8.5
7.7
16
20
I20.99
ICD-10 Finland
Angina pectoris, unspecified
5.2
7.7
23
48
N02BE01
ATC
paracetamol; systemic, rectal
2.8
7.7
191
1531
R99
ICPC
Respiratory disease other
12.5
7.7
13
11
B34.9
ICD-10 Finland
Viral infection, unspecified
7.6
7.6
17
24
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
26.0
7.6
10
*
UJC12
NOMESCO Finland
Flexible oesophagoscopy
26.0
7.6
10
*
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
4.6
7.5
25
59
TQW99
NOMESCO Finland
Other minor procedure on skin
5.5
7.5
21
41
GX1D5
NOMESCO Finland
Flow volume spirometry
82.7
7.5
8
*
R03DX07
ATC
roflumilast; oral
82.7
7.5
8
*
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
9.9
7.4
14
15
TFP20
NOMESCO Finland
Cardiodefibrillation
4.2
7.4
27
70
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
4.2
7.4
27
70
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.3
7.4
37
126
AA1AD
NOMESCO Finland
CT of head and brain
2.6
7.4
57
257
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
7.7
7.3
16
22
ZX196
NOMESCO Finland
NA
+∞
7.3
7
*
GDA10
NOMESCO Finland
Biopsy of lung
+∞
7.3
7
*
115
NOMESCO Finland
NA
+∞
7.3
7
*
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
16.4
7.3
11
7
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
16.4
7.3
11
7
R05CB02
ATC
bromhexine; systemic
16.4
7.3
11
7
WX722
NOMESCO Finland
PEEP
5.1
7.3
22
47
K03.66
ICD-10 Finland
Tooth plaque
4.0
7.2
28
77
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
4.0
7.2
28
77
J01MA02
ATC
ciprofloxacin; systemic
2.2
7.2
98
583
J96.0
ICD-10 Finland
Acute respiratory failure
12.6
7.2
12
10
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
3.5
7.2
33
105
L03AA02
ATC
filgrastim; parenteral
7.4
7.1
16
23
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
5.8
7.1
19
35
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
5.2
7.1
21
44
EBA15
NOMESCO Finland
Extraction of large number of teeth
5.4
7.0
20
40
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
14.4
7.0
11
8
R04.2
ICD-10 Finland
Haemoptysis
7.1
7.0
16
24
A41.9
ICD-10 Finland
Sepsis, unspecified
6.0
6.9
18
32
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
9.8
6.9
13
14
WX199
NOMESCO Finland
Other local analgesia
9.8
6.9
13
14
UJF32
NOMESCO Finland
Coloscopy
2.4
6.9
67
340
R4130
NOMESCO Finland
Speech therapy
7.6
6.8
15
21
ZXC50
NOMESCO Finland
Cryotherapy
7.6
6.8
15
21
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
5.5
6.8
19
37
EB1WA
NOMESCO Finland
NA
17.4
6.8
10
6
K23.8*B37.8
ICD-10 Finland
Esophagitis caused by candidiasis
41.4
6.8
8
*
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
41.4
6.8
8
*
I27.8
ICD-10 Finland
Other specified pulmonary heart diseases
41.4
6.8
8
*
A01AB09
ATC
miconazole; local oral
3.9
6.8
27
76
K29.7
ICD-10 Finland
Gastritis, unspecified
6.8
6.8
16
25
J01FF01
ATC
clindamycin; systemic
2.3
6.7
72
382
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
8.2
6.7
14
18
H25.1
ICD-10 Finland
Senile nuclear cataract
2.9
6.7
41
159
A07AA09
ATC
vancomycin; oral
12.8
6.7
11
9
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
9.1
6.6
13
15
WX100
NOMESCO Finland
Conjunctival surface anesthesia
4.1
6.6
25
67
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
7.2
6.6
15
22
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.4
6.6
31
100
J05AB01
ATC
aciclovir; systemic
2.5
6.6
57
270
R5140
NOMESCO Finland
Monitoring the use of the aid
3.1
6.6
37
136
F43.29
ICD-10 Finland
Adaptation disorder UNS
7.8
6.5
14
19
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.5
6.5
30
96
WZC30
NOMESCO Finland
Teaching
2.7
6.5
47
203
Z31.5
ICD-10 Finland
Genetic counselling
5.5
6.5
18
35
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
71.8
6.5
7
*
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
14.9
6.5
10
7
KA1AE
NOMESCO Finland
Kidney ultrasound examination
5.8
6.4
17
31
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
8.6
6.4
13
16
XG460
NOMESCO Finland
Short time oxymetry
8.6
6.4
13
16
C03DA01
ATC
spironolactone; oral
3.4
6.4
30
97
C01AA05
ATC
digoxin; systemic
5.1
6.4
19
40
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
3.8
6.4
26
75
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
9.7
6.4
12
13
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
11.5
6.4
11
10
Z50.1
ICD-10 Finland
Other physical therapy
4.5
6.3
21
50
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
18.7
6.3
9
5
RS224
NOMESCO Finland
NA
18.7
6.3
9
5
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
+∞
6.3
6
*
C02KX04
ATC
macitentan; oral
+∞
6.3
6
*
N02AA01
ATC
morphine; systemic, rectal
+∞
6.3
6
*
Y83.0
ICD-10 Finland
Surgical operation with transplant of whole organ as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
+∞
6.3
6
*
NA3SA
NOMESCO Finland
Lumbar spine X-ray examination in standing position
+∞
6.3
6
*
B01AC21
ATC
treprostinil; parenteral
+∞
6.3
6
*
GCA18
NOMESCO Finland
Bronchoscopic dilatation of bronchus
+∞
6.3
6
*
334
Kela drug reimbursment
Treprostinil
+∞
6.3
6
*
JC2FN
NOMESCO Finland
Scintigraphy of oesophageal function
+∞
6.3
6
*
J93.0
ICD-10 Finland
Spontaneous tension pneumothorax
+∞
6.3
6
*
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
6.1
6.3
16
28
R03AC12
ATC
salmeterol; inhalant
6.1
6.3
16
28
XX7LW
NOMESCO Finland
NA
27.5
6.3
8
*
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
27.5
6.3
8
*
XX2XT
NOMESCO Finland
Other injection with other radiological guidance
27.5
6.3
8
*
D64.9
ICD-10 Finland
Anaemia, unspecified
3.6
6.2
27
82
J01FA06
ATC
roxithromycin; oral
2.1
6.2
95
586
XFE00
NOMESCO Finland
Epicardial ultrasonography
8.0
6.2
13
17
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
4.1
6.2
23
61
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
3.1
6.2
34
122
R01AD09
ATC
mometasone; nasal
2.0
6.2
104
668
XF602
NOMESCO Finland
Bloodpressure monitoring
13.0
6.1
10
8
C02CA01
ATC
prazosin; oral
13.0
6.1
10
8
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
9.0
6.1
12
14

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
189
34
224.72
307.65
5.6
1.6
—
—
—
0
0
189
34
224.72
307.65
5.6
1.6
—
—
—
0
0
189
34
224.72
307.65
5.6
1.6
—
—
—
0
0
189
34
224.72
307.65
5.6
1.6
—
—
—
0
0
233
187
169.53
280.45
38.1
10.9
10.19
8.72
mmol/l
1.89
233
180
231
272
99.59
219.86
20.2
8.7
1.09
1.06
mmol/l
0.76
231
256
121
32
72.34
208.20
4.5
2.7
—
—
—
0
0
177
146
39.09
201.12
4.5
1.5
—
—
—
0
0
209
248
46.29
193.77
34.7
8.5
105.21
103.70
mmol/l
3.77
209
241
164
8
591.89
186.68
4.3
1.4
35.10
71.11
ug/l
—
164
8
93
10
147.50
184.74
1.0
1.1
—
—
—
0
0
93
10
147.50
184.74
1.0
1.0
—
—
—
0
0
229
355
65.89
177.31
38.6
4.3
0.78
0.81
mmol/l
5.22
229
335
205
269
37.78
176.04
8.9
1.4
—
—
—
0
0
123
63
37.46
170.47
1.6
1.5
—
—
—
0
0
187
222
30.46
169.80
6.7
1.4
—
—
—
0
0
97
25
62.76
165.94
1.1
1.2
—
—
—
0
0
128
78
32.58
164.66
7.4
2.3
396.95
291.89
ug/l
0.53
128
72
100
32
51.42
161.62
1.2
1.2
—
—
—
0
0
100
32
51.42
161.62
2.3
2.4
—
—
—
0
0
117
60
35.77
161.49
1.5
1.5
103.42
84.90
u/ml
—
13
10
98
35
45.41
152.96
1.3
1.3
—
—
—
0
0
205
323
30.70
152.36
7.5
2.0
—
—
—
0
0
115
65
31.91
151.95
1.2
1.5
412.87
214.71
u/ml
4.14
88
35
207
333
31.33
151.54
9.5
2.8
0.82
1.99
e6/l
1.76
179
186
91
39
36.12
132.82
1.3
1.3
3.98
5.56
u/ml
0.31
43
18
117
93
22.77
130.02
1.3
1.5
—
—
—
0
0
190
325
21.19
129.28
7.7
2.6
29.65
29.46
s
0.14
190
317
117
9
241.91
121.96
4.3
4.9
—
—
—
0
0
136
160
17.45
118.76
2.8
2.5
35.95
9.21
ug/l
12.74
136
140
232
570
43.64
117.79
19.5
4.6
7.39
7.40
ph
1.72
46
112
221
526
28.60
113.90
19.4
4.4
100.40
91.36
%
5.39
221
520
196
400
19.06
113.86
10.6
2.7
548.63
584.89
mosm/kgh2o
1.41
190
343
226
568
32.03
110.81
15.8
2.9
—
—
—
0
0
203
455
19.41
108.31
4.1
1.5
2.05
2.51
g/l
2.23
194
282
226
588
30.62
106.68
16.1
3.0
0.11
0.45
e6/l
2.09
214
445
160
277
14.27
103.99
5.3
2.7
18.92
23.45
%
3.14
148
241
215
539
22.35
103.71
30.3
7.8
—
—
—
0
0
180
365
15.04
102.98
9.4
2.7
0.21
1.04
e6/l
5.06
160
217
227
643
28.50
97.42
18.0
3.1
7.67
145.17
e6/l
0.79
218
504
73
44
23.02
91.17
2.6
2.5
120.88
136.17
g/l
2.04
17
35
107
128
13.87
90.02
7.8
3.5
142.81
180.34
ng/l
0.47
102
110
191
473
13.87
89.75
6.7
3.4
—
—
—
0
0
215
616
18.79
88.89
16.5
2.2
88.18
215.14
u/l
4.57
215
583
231
750
28.37
84.54
44.9
6.7
—
—
—
0
0
228
735
24.89
83.63
22.4
3.5
25.09
109.06
e6/l
0.83
219
535
112
160
11.87
82.10
1.6
1.6
—
—
—
0
0
197
559
12.91
79.63
10.4
4.8
—
—
—
0
0
241
965
42.55
78.69
49.5
8.5
1.19
1.21
mmol/l
2.57
234
822
218
728
16.58
74.58
17.9
3.8
25.51
33.94
u/l
6.62
218
693
113
184
10.38
73.86
42.7
10.2
—
—
—
0
0
122
229
9.45
70.23
38.1
8.7
1.45
1.16
mmol/l
0.32
111
188
193
594
10.86
69.77
5.0
3.5
73.73
170.62
mg/l
0.41
159
389
95
136
10.65
68.43
6.3
5.2
—
—
—
0
0
111
192
9.60
68.41
12.6
5.3
0.64
0.78
%
0.37
63
65
170
466
9.28
68.38
5.9
2.0
1.48
1.25
mg/l
0.49
149
362
41
12
40.67
65.69
1.0
1.4
—
—
—
0
0
194
628
10.33
65.65
5.3
4.2
12.34
10.14
mg/mmol
0.22
159
402
52
32
20.26
63.41
2.2
2.3
—
—
—
0
0
144
364
7.97
61.40
5.8
3.9
3545.67
435.98
ng/l
4.51
137
276
81
109
10.51
60.70
8.8
7.8
24.09
24.07
mmol/l
0.02
70
101
123
268
8.07
60.55
2.0
1.7
—
—
—
0
0
104
192
8.56
59.67
10.1
6.6
1.53
1.85
mmol/l
0.26
87
161
120
265
7.79
57.97
2.7
1.6
—
—
—
0
0
127
307
7.38
55.77
2.0
1.7
—
—
—
0
0
154
453
7.25
54.99
3.7
2.1
3.34
3.19
mg/l
0.25
148
393
162
500
7.36
54.96
5.2
2.5
—
—
—
0
0
230
1000
17.25
54.82
48.3
9.9
0.00
0.00
e9/l
0.83
210
823
200
786
8.72
51.42
8.0
3.2
—
—
—
0
0
93
176
7.82
51.41
11.9
5.2
0.64
0.29
%
1.88
42
48
74
116
8.64
48.23
54.3
9.1
—
—
—
0
0
200
819
8.21
48.05
18.6
8.1
1.25
1.14
inr
0.77
56
256
32
12
30.43
47.16
1.6
1.4
2310.39
1300.57
e6/l
—
23
7
87
170
7.32
46.21
12.9
5.6
0.00
0.04
%
0.80
48
51
177
668
6.65
45.86
5.6
2.5
—
—
—
0
0
30
10
33.95
45.84
1.5
1.4
—
—
—
0
0
30
10
33.95
45.84
1.6
1.5
145048.10
33838.00
e6/l
—
21
5
197
820
7.62
45.64
5.0
2.0
—
—
—
0
0
130
377
6.10
45.46
2.0
1.9
—
—
—
0
0
50
9
68.95
44.36
1.1
1.8
—
—
—
0
0
86
174
7.01
43.96
13.7
5.6
0.18
0.18
%
0.00
57
57
30
12
28.27
43.14
1.5
1.4
—
—
—
0
0
78
146
7.31
42.93
8.0
5.2
115.44
85.96
ng/l
1.69
69
133
98
234
6.24
42.03
7.1
3.3
1.82
1.83
%
0.05
98
216
52
62
10.33
41.93
5.5
3.3
—
—
—
0
0
112
315
5.63
39.71
1.9
1.4
398.82
409.70
titre
0.03
34
66
212
1017
8.14
39.70
11.0
3.4
0.00
0.00
estimate
0.00
51
205
212
1020
8.09
39.47
15.9
4.6
0.00
0.00
estimate
0.00
54
212
213
1034
8.16
39.11
10.9
3.4
0.00
0.00
estimate
0.00
54
204
32
19
19.17
39.10
6.5
3.5
—
—
—
0
0
100
261
5.72
38.47
4.6
3.8
5.90
9.99
umol/l
1.51
90
234
142
508
5.16
37.16
5.3
2.7
—
—
—
0
0
237
1308
16.61
37.01
23.3
3.8
1.91
175.19
e6/l
0.56
11
21
84
194
6.01
36.86
2.7
2.7
39.74
32.21
u/l
0.91
78
162
33
24
15.69
36.33
6.9
3.6
—
—
—
0
0
49
65
9.13
36.17
1.1
1.5
190.20
292.29
miu/ml
—
5
28
53
79
8.24
35.50
10.5
8.9
1.95
1.41
mg/l
4.21
53
74
78
182
5.78
33.57
3.3
3.1
65.95
73.37
e9/l
0.87
53
135
110
350
4.83
32.60
1.5
1.3
19.30
29.70
iu/ml
0.67
29
121
238
1419
15.11
31.27
23.1
3.9
—
—
—
0
0
189
979
4.81
27.64
9.6
4.2
—
—
—
0
0
23
14
17.99
27.50
1.6
1.9
—
—
—
0
0
65
153
5.39
27.28
1.6
2.9
61.16
66.94
g/l
4.74
60
145
30
31
10.86
26.41
10.7
2.3
—
—
—
0
0
31
8
43.90
25.55
1.7
1.8
—
—
—
0
0
64
159
5.07
25.08
1.2
1.7
—
—
—
0
0
73
207
4.57
24.24
1.9
1.4
—
—
—
0
0
31
38
9.17
24.04
6.9
3.8
56.52
57.45
%
0.14
31
38
27
5
60.22
23.57
1.1
1.0
—
—
—
0
0
30
37
9.08
23.13
6.2
3.1
3.97
4.33
e9/l
0.31
30
37
120
510
3.60
22.04
24.3
4.8
—
—
—
0
0
52
124
5.03
21.19
9.9
2.6
0.23
0.13
e6/l
0.44
52
119
50
116
5.14
21.03
1.6
1.2
—
—
—
0
0
27
33
9.05
20.91
5.1
3.0
—
—
—
0
0
30
44
7.61
20.00
13.2
3.6
5.29
5.01
kpa
0.87
30
44
30
44
7.61
20.00
13.2
3.6
8.57
8.72
kpa
0.12
30
44
30
44
7.61
20.00
13.2
3.6
2.87
2.31
mmol/l
0.45
20
28
18
14
13.78
18.75
1.7
3.6
10.80
15.13
%
—
10
8
35
65
6.10
18.66
13.8
3.8
8.88
8.86
kpa
0.02
35
60
221
1480
5.25
18.62
22.6
3.7
—
—
—
0
0
128
618
3.20
18.27
1.9
1.4
—
—
—
0
0
58
169
4.17
18.20
13.0
4.1
7.40
7.42
ph
0.84
12
17
18
16
12.05
17.29
1.4
1.3
—
—
—
0
0
78
288
3.48
17.24
1.3
1.3
—
—
—
0
0
68
231
3.67
17.07
2.9
1.5
—
—
—
0
0
27
42
7.09
17.02
12.1
3.9
—
—
—
0
0
36
75
5.44
16.96
12.3
5.2
—
—
—
0
0
54
159
4.06
16.61
12.3
4.6
1.22
1.22
mmol/l
0.14
54
143
33
66
5.61
16.23
1.5
1.2
—
—
—
0
0
90
375
3.19
16.19
1.8
1.6
506.00
446.06
pmol/l
0.98
81
317
25
38
7.20
16.07
6.8
6.1
63.84
67.62
%
0.32
25
38
23
32
7.81
15.95
11.3
4.1
—
—
—
0
0
31
60
5.76
15.77
1.4
1.2
—
—
—
0
0
220
1547
4.52
15.43
5.3
3.7
14.00
14.77
pmol/l
5.16
214
1402
24
39
6.70
14.48
5.5
2.4
16.01
17.66
%
0.95
16
19
14
12
12.30
13.64
2.1
2.8
—
—
—
0
0
22
36
6.60
13.17
8.7
4.0
—
—
—
0
0
138
798
2.63
12.66
5.7
3.6
67.12
37.24
ng/l
1.75
127
549
13
12
11.37
12.05
1.3
1.2
—
—
—
0
0
16
7
24.28
11.72
4.1
2.6
24.94
27.29
umol/l
—
16
7
40
121
3.74
11.67
1.5
2.4
—
—
—
0
0
22
44
5.39
10.73
7.3
6.6
—
—
—
0
0
69
309
2.70
10.32
1.7
1.6
1033.90
1211.97
nmol/l
0.96
61
243
40
132
3.42
10.20
12.9
4.4
—
—
—
0
0
102
559
2.39
9.89
12.3
3.6
0.00
0.00
estimate
0.50
51
204
12
5
25.09
8.99
1.0
1.2
—
—
—
0
0
19
39
5.19
8.99
1.4
1.9
—
—
—
0
0
24
61
4.25
8.83
11.8
4.2
4.01
3.84
mmol/l
1.43
19
55
240
2008
5.88
8.79
97.4
14.7
36.02
40.80
%
34.65
225
1525
12
6
20.90
8.55
2.8
6.3
—
—
—
0
0
20
45
4.74
8.53
1.3
1.2
—
—
—
0
0
13
19
7.16
8.52
1.4
9.5
9.85
11.79
%
1.19
13
19
116
714
2.17
8.14
2.0
1.9
95.85
95.28
pmol/l
0.05
64
370
15
27
5.85
8.12
1.3
1.2
—
—
—
0
0
15
28
5.64
7.83
1.1
1.2
—
—
—
0
0
43
843
0.41
6.84
3.0
2.8
—
—
—
0
0
10
14
7.40
6.75
2.4
1.4
0.13
0.19
e9/l
—
10
14
9
5
18.59
6.31
1.3
1.0
—
—
—
0
0
226
1907
2.93
6.29
8.2
4.3
1.87
1.92
mu/l
0.34
221
1748
10
16
6.47
6.00
1.7
1.6
—
—
—
0
0
94
585
1.97
5.99
10.6
2.9
—
—
—
0
0
47
230
2.29
5.58
40.1
18.3
1.99
1.42
inr
—
7
27
77
457
1.99
5.56
10.2
3.6
1.01
1.02
kg/l
—
5
66
8
5
16.45
5.44
2.4
1.4
6.25
7.00
%
—
8
5
8
5
16.45
5.44
2.4
1.4
—
—
—
0
0
38
171
2.44
5.44
8.2
3.5
—
—
—
0
0
15
39
4.03
5.34
1.1
2.2
—
—
—
0
0
21
71
3.14
5.12
1.1
1.2
—
—
—
0
0
15
41
3.83
5.00
1.7
2.1
—
—
—
0
0
23
84
2.91
4.93
6.5
5.9
0.42
0.29
g/l
0.29
16
46
29
121
2.58
4.85
12.8
4.8
24.42
25.03
mmol/l
0.53
29
114
16
47
3.57
4.83
1.3
1.8
0.41
0.94
g/l
0.93
11
39
17
54
3.30
4.58
3.0
3.4
—
—
—
0
0
0
109
0.00
4.31
0.0
1.6
—
—
—
0
0
37
186
2.16
4.09
14.0
3.4
—
—
—
0
0
7
236
0.28
3.83
1.4
1.4
—
—
—
0
0
9
17
5.45
3.54
1.6
1.6
—
—
—
0
0
47
276
1.87
3.38
1.4
1.2
—
—
—
0
0
8
14
5.86
3.37
1.0
1.0
—
—
—
0
0
77
525
1.67
3.32
1.5
2.8
0.50
0.74
ug/l
3.55
54
337
17
66
2.69
3.29
1.0
1.5
257.12
288.98
ug/g
—
8
41
8
15
5.47
3.21
1.0
1.1
—
—
—
0
0
23
106
2.29
3.14
2.0
2.3
—
—
—
0
0
8
16
5.13
3.07
1.4
1.7
12.13
11.12
umol/l
—
8
16
7
12
5.97
3.04
1.1
6.6
—
—
—
0
0
8
17
4.82
2.94
1.4
1.4
—
—
—
0
0
10
30
3.43
2.94
1.3
1.3
—
—
—
0
0
10
31
3.32
2.80
1.5
1.4
—
—
—
0
0
11
37
3.06
2.73
1.1
1.1
—
—
—
0
0
9
24
3.85
2.70
1.8
1.2
—
—
—
0
0
11
38
2.98
2.61
1.5
1.1
—
—
—
0
0
11
38
2.98
2.61
1.5
1.1
—
—
—
0
0
7
15
4.77
2.61
2.7
1.3
0.95
0.66
u/ml
—
7
8
7
15
4.77
2.61
1.7
1.9
0.88
1.00
g/l
—
7
15
5
7
7.26
2.56
1.2
1.0
1609.60
1555.57
miu/ml
—
5
7
115
905
1.50
2.55
3.2
4.5
1.40
1.98
ug/l
2.27
97
820
6
12
5.09
2.41
4.7
2.5
559.33
517.43
min
—
6
7
9
28
3.29
2.33
1.8
1.5
—
—
—
0
0
26
144
1.90
2.25
2.8
2.3
3.43
4.10
e9/l
1.04
19
116
5
9
5.64
2.22
1.8
3.1
—
—
—
0
0
6
15
4.07
2.05
4.0
2.5
804.17
645.75
ml
—
6
8
7
21
3.40
1.98
1.0
1.1
—
—
—
0
0
7
21
3.40
1.98
2.1
3.3
—
—
—
0
0
16
78
2.12
1.95
1.7
1.2
—
—
—
0
0
33
206
1.69
1.95
2.5
4.7
19.68
42.13
ug/l
0.36
25
164
5
11
4.61
1.95
1.2
7.3
—
—
—
0
0
5
12
4.23
1.83
1.4
6.7
—
—
—
0
0
7
24
2.97
1.73
1.1
1.2
—
—
—
0
0
238
2271
2.00
1.56
48.2
13.0
—
—
—
0
0
5
15
3.38
1.53
1.2
1.3
—
—
—
0
0
9
37
2.48
1.49
4.4
1.5
—
—
—
0
0
13
67
1.99
1.41
4.2
2.6
—
—
—
0
0
7
29
2.45
1.40
1.3
1.1
—
—
—
0
0
9
41
2.24
1.38
1.1
1.0
—
—
—
0
0
75
606
1.34
1.28
7.3
3.7
—
—
—
0
0
6
25
2.43
1.25
1.0
1.2
—
—
—
0
0
6
25
2.43
1.25
2.5
1.7
11.29
18.68
ug/l
—
6
25
10
52
1.96
1.07
1.1
2.1
1.44
3915.88
u/l
—
5
17
9
49
1.87
0.99
2.2
2.2
1217.22
2370.32
e6/l
—
9
40
9
49
1.87
0.99
2.2
2.0
6.44
10.08
e6/l
—
9
39
21
141
1.53
0.98
1.2
1.3
—
35.81
—
0
8
0
29
0.00
0.98
0.0
1.3
—
61.68
—
0
8
0
29
0.00
0.98
0.0
1.1
—
3.24
—
0
13
0
31
0.00
0.97
0.0
1.1
—
0.56
—
0
11
36
272
1.38
0.94
2.0
2.6
198.68
108.47
ug/g
0.73
31
222
33
247
1.39
0.91
1.6
1.3
—
—
—
0
0
14
88
1.63
0.86
4.1
1.6
—
—
—
0
0
6
31
1.96
0.85
1.3
1.0
—
—
—
0
0
22
156
1.45
0.82
2.3
2.5
—
19.66
—
0
8
27
200
1.39
0.80
19.2
4.9
—
—
—
0
0
0
27
0.00
0.78
0.0
1.1
—
10.02
—
0
14
59
493
1.26
0.77
1.4
1.3
0.41
1.30
u/ml
1.43
17
135
7
41
1.73
0.70
2.3
2.3
—
—
—
0
0
7
119
0.58
0.69
1.0
1.1
—
—
—
0
0
5
27
1.87
0.69
1.0
1.3
—
—
—
0
0
0
20
0.00
0.60
0.0
1.5
—
—
—
0
0
0
21
0.00
0.60
0.0
1.5
—
—
—
0
0
6
36
1.68
0.57
1.0
1.6
—
—
—
0
0
6
92
0.64
0.43
1.0
1.1
—
—
—
0
0
10
70
1.45
0.42
1.5
1.5
—
—
—
0
0
5
33
1.53
0.41
2.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
242.00
—
0
9
0
17
0.00
0.41
0.0
1.2
—
13872.17
—
0
12
0
19
0.00
0.39
0.0
15.2
—
1325.79
—
0
19
9
70
1.30
0.37
15.1
12.1
—
—
—
0
0
11
81
1.37
0.37
1.0
1.4
—
—
—
0
0
11
82
1.36
0.34
1.0
1.4
—
—
—
0
0
11
83
1.34
0.32
1.0
1.4
—
—
—
0
0
11
83
1.34
0.32
1.0
1.4
—
—
—
0
0
7
55
1.28
0.30
4.6
3.9
—
—
—
0
0
8
62
1.30
0.28
1.0
1.4
—
—
—
0
0
16
132
1.23
0.26
4.4
2.1
—
—
—
0
0
5
74
0.67
0.26
1.0
1.8
—
—
—
0
0
9
77
1.18
0.24
1.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
2.4
—
5.65
—
0
11
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
7.79
—
0
12
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
10.8
—
0.61
—
0
14
38
348
1.11
0.19
1.3
1.3
24.69
9.29
u/ml
0.38
16
145
21
186
1.14
0.17
1.3
1.2
—
—
—
0
0
7
63
1.11
0.17
1.4
1.5
290.29
355.38
mu/l
—
7
58
20
225
0.88
0.17
1.1
1.5
—
—
—
0
0
12
105
1.15
0.11
8.0
3.2
—
—
—
0
0
5
44
1.14
0.10
3.6
1.7
—
—
—
0
0
11
112
0.98
0.00
1.2
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
48.33
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
5
56
0.89
0.00
1.2
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
154.25
—
0
6
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
0.00
1.2
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
1.94
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
17.30
—
0
7
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
3.1
—
1.63
—
0
7
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
6.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
21.84
—
0
5
0
9
0.00
0.00
0.0
6.7
—
7.58
—
0
9

Mortality – FinRegistry

↥

Association

Association between endpoint Z21_LUNG_TRANSPLANT_STATUS and mortality.

Females

Parameter HR [95% CI] p-value
Z21_LUNG_TRANSPLANT_STATUS 6.846 [4.54, 10.33] < 0.001
Birth year 0.999 [0.99, 1.01] 0.826

During the follow-up period (1.1.1998 — 31.12.2019), 72 out of 230 females with Z21_LUNG_TRANSPLANT_STATUS died.

Males

Parameter HR [95% CI] p-value
Z21_LUNG_TRANSPLANT_STATUS 5.555 [3.49, 8.85] < 0.001
Birth year 0.985 [0.98, 0.99] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 117 out of 314 males with Z21_LUNG_TRANSPLANT_STATUS died.

Mortality risk

Mortality risk for people of age

years, who have Z21_LUNG_TRANSPLANT_STATUS.

N-year risk Females Males
1 0.828% 1.106%
5 4.172% 6.44%
10 11.641% 15.219%
15 20.622% 26.458%
20 34.009% 41.682%

Relationships between endpoints

↥

Index endpoint: Z21_LUNG_TRANSPLANT_STATUS – Lung transplant status

GWS hits: 4

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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