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Lung transplantation

MESH Endpoint Browser PheWeb

LUNG_TRANSPLANTATION

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

251

6. Filter based on genotype QC (FinnGen only)

251

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF5

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 635 264 371
Only index persons 569 239 330
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population - 54.38 58.17
Only index persons 56.75 54.62 58.30

-FinnGen-

Key figures

All Female Male
Number of individuals 251 103 148
Unadjusted period prevalence (%) 0.05 0.04 0.07
Median age at first event (years) 57.10 54.62 58.83

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
223
Matched controls
2229
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Z94.2
ICD-10 Finland
Lung transplant status
+∞
319.6
222
*
127
Kela drug reimbursment
Transplant complication
890.6
238.3
199
20
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
7062.7
214.2
171
*
L04AA06
ATC
mycophenolic acid; systemic
456.9
210.9
186
24
GDG10
NOMESCO Finland
Bilateral transplantation of lung
+∞
198.9
160
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
116.8
157.8
167
55
UGC12
NOMESCO Finland
Flexible bronchoscopy
86.9
148.9
169
77
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
104.9
138.7
147
40
TGC00
NOMESCO Finland
Bronchial lavation
133.6
137.0
139
27
L04AD01
ATC
ciclosporin; systemic
165.7
135.9
134
20
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
1150.6
130.5
115
*
GD1AD
NOMESCO Finland
Thorax CT examination
87.1
128.1
140
42
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
44.3
122.5
183
208
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
202.3
120.8
117
12
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
56.2
117.2
142
67
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
49.7
115.1
145
80
GD1BT
NOMESCO Finland
Biopsy of lung with X-ray guidance
+∞
112.2
98
*
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
385.8
111.9
104
5
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
41.2
111.4
197
345
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
245.1
109.6
105
8
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
60.8
109.2
128
48
R4110
NOMESCO Finland
Physiotherapy
39.2
106.3
199
389
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
46.9
103.0
129
63
GD1AA
NOMESCO Finland
Thorax X-ray examination
56.2
94.2
213
612
C08CA02
ATC
felodipine; oral
36.6
93.8
126
76
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
61.9
91.8
106
32
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
51.0
87.2
105
38
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
21.2
84.5
148
189
XX4BW
NOMESCO Finland
NA
1160.3
84.3
77
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
19.8
81.2
146
194
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
27.6
79.5
116
84
WX872
NOMESCO Finland
Intensive care
35.7
79.3
105
54
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
17.7
78.4
174
371
ZX108
NOMESCO Finland
Inhalation
179.2
73.0
73
6
WX302
NOMESCO Finland
Thoracal epidural anesthesy
34.1
72.8
97
49
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
93.1
69.8
75
12
J18.9
ICD-10 Finland
Pneumonia, unspecified
14.6
67.4
140
231
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
29.9
65.9
91
50
WX404
NOMESCO Finland
Intravenous generell anesthesy
13.1
64.6
149
297
H02AB06
ATC
prednisolone; systemic
17.1
63.5
198
706
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
277.7
62.6
61
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
18.7
60.8
101
94
C03CA01
ATC
furosemide; systemic
12.3
59.8
135
247
WX408
NOMESCO Finland
General anesthesy, balanced
11.3
58.9
160
409
C10AA03
ATC
pravastatin; oral
23.5
58.9
88
60
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
11.9
58.1
133
246
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
20.7
56.8
89
69
5AB14
NOMESCO Finland
NA
+∞
55.6
51
*
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
41.0
55.2
69
24
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
145.0
53.6
55
5
L04AX01
ATC
azathioprine; systemic
25.9
51.2
73
41
ZX120
NOMESCO Finland
Intravenous
14.3
50.9
95
110
A07AA02
ATC
nystatin; oral
20.1
49.8
78
58
J96.1
ICD-10 Finland
Chronic respiratory failure
65.8
48.5
55
11
GD1RA
NOMESCO Finland
Dynamic X-ray examination of respiratory organs with convetional X-ray picture
555.1
47.1
45
*
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
197.1
46.8
47
*
ZXA10
NOMESCO Finland
Bilateral
9.5
46.2
115
224
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
18.2
45.0
73
58
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
14.9
44.3
79
79
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
23.0
44.2
65
39
J01MA14
ATC
moxifloxacin; systemic
12.3
39.9
78
93
284
Kela drug reimbursment
Nintedanib and pirfenidone
435.8
38.2
37
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
7.4
37.9
114
277
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
83.1
37.4
41
6
C07AB07
ATC
bisoprolol; oral
6.4
36.6
157
600
C10AA01
ATC
simvastatin; oral
6.3
36.3
151
553
2AX04
NOMESCO Finland
NA
407.6
36.0
35
*
XG410
NOMESCO Finland
Flow-volume spirometry
19.3
36.0
56
38
JN4BD
NOMESCO Finland
Extensive body CT
9.2
35.2
82
132
RS123
NOMESCO Finland
NA
403.3
34.9
34
*
5BA08
NOMESCO Finland
NA
199.3
33.7
34
*
XG466
NOMESCO Finland
Sleep oxymetry
22.9
33.7
49
27
C09AA05
ATC
ramipril; oral
6.5
33.5
109
284
R4190
NOMESCO Finland
Nutritional therapy
19.0
33.4
52
35
L04AX05
ATC
pirfenidone; oral
+∞
33.1
31
*
R03BB04
ATC
tiotropium bromide; inhalant
12.0
33.1
64
72
TPH04
NOMESCO Finland
Cathetrisation of vein
6.7
32.6
102
250
A02BA03
ATC
famotidine; systemic
24.8
32.5
46
23
R03AC02
ATC
salbutamol; inhalant
6.0
32.2
172
798
3A006
NOMESCO Finland
NA
+∞
32.0
30
*
TK800
NOMESCO Finland
Hemodialysis
21.9
31.3
46
26
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
17.5
31.2
50
36
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
10.7
30.7
63
79
Z94.0
ICD-10 Finland
Kidney transplant status
36.0
30.6
39
13
WX402
NOMESCO Finland
General anaesthesia
6.5
30.4
94
223
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
28.3
29.5
40
17
356
Kela drug reimbursment
Nintedanib and pirfenidone
332.8
29.5
29
*
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
12.6
29.0
54
55
R50.9
ICD-10 Finland
Fever, unspecified
7.6
29.0
76
142
TPH07
NOMESCO Finland
Cathetrisation of artery
8.6
28.7
68
108
WX892
NOMESCO Finland
Monitored bed care
10.5
28.6
59
74
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
6.5
28.0
85
193
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
5.3
27.8
170
844
ZX197
NOMESCO Finland
NA
+∞
27.7
26
*
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
305.7
27.3
27
*
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
22.2
26.8
39
21
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
28.3
26.7
36
15
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
46.3
26.6
32
8
WX740
NOMESCO Finland
Nitrogen oxide therapy
+∞
26.6
25
*
XJC10
NOMESCO Finland
Oesophageal pH monitoring
106.2
26.3
28
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
22.6
26.3
38
20
R06.0
ICD-10 Finland
Dyspnoea
5.3
26.3
100
295
Z94.1
ICD-10 Finland
Heart transplant status
152.6
26.2
27
*
R03AK07
ATC
formoterol and budesonide; inhalant
5.9
26.2
87
219
AN1
HP
Coronary angiography
8.4
25.9
61
95
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
8.6
25.9
60
91
L04AA01
ATC
[U] ciclosporin; systemic
23.6
25.3
36
18
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
10.3
25.2
52
64
XX4AW
NOMESCO Finland
NA
146.3
25.2
26
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
9.9
24.8
52
66
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
8.5
24.6
57
86
M05BA04
ATC
alendronic acid; oral
10.1
24.1
50
62
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
6.6
24.0
69
142
ZX100
NOMESCO Finland
Oral
32.4
23.9
31
11
XF400
NOMESCO Finland
ECG with 12 standard connections
5.8
23.6
76
181
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
26.4
23.3
32
14
J01MA12
ATC
levofloxacin; systemic
5.4
23.3
83
222
1CX01
NOMESCO Finland
NA
133.7
23.1
24
*
137
Kela drug reimbursment
Uraemia requiring dialysis
50.9
22.9
27
6
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
4.2
22.8
146
689
ZXA00
NOMESCO Finland
Right side
4.6
22.8
102
346
A11CC03
ATC
alfacalcidol; systemic
21.3
22.5
33
18
FXD00
NOMESCO Finland
Use of ECHLA without concurrent surgical procedure
+∞
22.2
21
*
AK3
HP
BLTX (both lung transplants)
+∞
22.2
21
*
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
11.1
22.1
43
47
Z49.2
ICD-10 Finland
Other dialysis
55.9
21.6
25
5
B05DA
ATC
Isotonic solutions
55.9
21.6
25
5
B01AB04
ATC
dalteparin; parenteral
12.5
21.4
39
37
RS230
NOMESCO Finland
NA
66.8
21.3
24
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.3
20.6
71
179
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
4.9
20.4
79
226
J43.9
ICD-10 Finland
Emphysema, unspecified
63.7
20.3
23
*
N18.8
ICD-10 Finland
Other chronic renal failure
20.2
20.2
30
17
J01FA10
ATC
azithromycin; systemic
4.1
20.0
170
980
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
20.6
19.7
29
16
RD210
NOMESCO Finland
NA
15.3
19.4
32
24
GBB00
NOMESCO Finland
Tracheostomy
38.1
19.3
24
7
N02AX02
ATC
tramadol; systemic, rectal
3.7
19.3
135
651
RS221
NOMESCO Finland
NA
17.1
19.1
30
20
E88.0
ICD-10 Finland
Disorders of plasma-protein metabolism, not elsewhere classified
206.5
18.8
19
*
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
14.2
18.8
32
26
R52.0
ICD-10 Finland
Acute pain
17.6
18.0
28
18
B01AA03
ATC
warfarin; systemic
4.9
17.9
65
171
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
6.0
17.9
53
110
TPX10
NOMESCO Finland
Implantation of vascular injection port
15.7
17.9
29
21
Z94.3
ICD-10 Finland
Heart and lungs transplant status
194.7
17.8
18
*
R03AC13
ATC
formoterol; inhalant
13.1
17.7
31
27
R03AK06
ATC
salmeterol and fluticasone; inhalant
5.1
17.5
61
153
TDM10
NOMESCO Finland
Puncture of maxillary antrum
10.6
17.4
34
37
J93.1
ICD-10 Finland
Other spontaneous pneumothorax
68.8
17.0
19
*
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
19.9
16.9
25
14
I27.0
ICD-10 Finland
Primary pulmonary hypertension
+∞
16.9
16
*
E84.0
ICD-10 Finland
Cystic fibrosis with pulmonary manifestations
+∞
16.9
16
*
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
9.8
16.7
34
40
B05DB
ATC
Hypertonic solutions
51.6
16.3
19
*
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
13.2
16.1
28
24
B07.9
ICD-10 Finland
Verruca simplex
11.4
16.0
30
30
J01GB01
ATC
tobramycin; inhalant, parenteral
64.8
16.0
18
*
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
64.8
16.0
18
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
8.0
16.0
37
54
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
4.3
15.9
67
202
Z49.1
ICD-10 Finland
Extracorporeal dialysis
28.7
15.9
21
8
N02AA05
ATC
oxycodone; systemic
5.3
15.9
52
121
RK110
NOMESCO Finland
NA
91.6
15.8
17
*
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
171.4
15.7
16
*
B03XA01
ATC
erythropoietin; parenteral
41.2
15.6
19
5
RK320
NOMESCO Finland
NA
41.2
15.6
19
5
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
25.6
15.4
21
9
A02BC05
ATC
esomeprazole; systemic
3.2
15.3
122
608
XJC02
NOMESCO Finland
Mesurement of oesophageal pressure and pressure profile of lower oesophageal sphincter
48.7
15.3
18
*
ZX121
NOMESCO Finland
Central venous catheter
48.7
15.3
18
*
JN4AD
NOMESCO Finland
Body CT examination
6.3
15.2
42
79
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
60.9
15.0
17
*
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
60.9
15.0
17
*
Z94.4
ICD-10 Finland
Liver transplant status
60.9
15.0
17
*
J01CA04
ATC
amoxicillin; systemic
5.1
15.0
204
1512
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
27.3
15.0
20
8
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
27.3
15.0
20
8
R03BB01
ATC
ipratropium bromide; inhalant
23.0
15.0
21
10
AP2
HP
Catheterization of the right side of the heart
+∞
14.7
14
*
R05CB13
ATC
dornase alfa (desoxyribonuclease); inhalant
+∞
14.7
14
*
304
Kela drug reimbursment
Dornase alfa
+∞
14.7
14
*
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
10.2
14.7
29
32
Z01.8
ICD-10 Finland
Other specified special examinations
3.7
14.7
78
286
H02AB04
ATC
methylprednisolone; systemic
4.3
14.6
61
181
A02BC01
ATC
omeprazole; systemic
3.5
14.6
83
321
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
24.2
14.5
20
9
A02BC02
ATC
pantoprazole; systemic
3.2
14.5
164
1029
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
25.8
14.0
19
8
H26.3
ICD-10 Finland
Drug-induced cataract
36.6
13.7
17
5
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
36.6
13.7
17
5
FXF00
NOMESCO Finland
Decannulation after ECHLA or ECLA
+∞
13.7
13
*
3A064
NOMESCO Finland
NA
+∞
13.7
13
*
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
12.6
13.7
24
21
T86.8
ICD-10 Finland
Failure and rejection of other transplanted organs and tissues
148.5
13.6
14
*
J45.9
ICD-10 Finland
Asthma, unspecified
4.0
13.6
61
193
B03XA02
ATC
darbepoetin alfa; parenteral
15.1
13.6
22
16
C10AX09
ATC
ezetimibe; oral
4.5
13.5
51
137
WW200
NOMESCO Finland
Immunization
8.4
13.2
29
39
R03DA04
ATC
theophylline; systemic, rectal
10.0
13.1
26
29
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
4.9
13.1
45
109
WX720
NOMESCO Finland
Own respiration
10.7
13.1
25
26
SAA04
NOMESCO Finland
Special inverstigation of mouth
6.6
13.0
34
59
M81.9
ICD-10 Finland
Osteoporosis, unspecified
15.3
13.0
21
15
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
5.2
13.0
42
95
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
10.3
12.9
25
27
SAA03
NOMESCO Finland
Extended examination of mouth
2.9
12.8
122
657
SPAT1325
SPAT
Vaccination
3.0
12.8
96
445
RS220
NOMESCO Finland
NA
18.7
12.8
19
11
TK820
NOMESCO Finland
Peritoneal dialysis
74.1
12.7
14
*
JN4CD
NOMESCO Finland
Very extensive body CT
9.3
12.7
26
31
FXE00
NOMESCO Finland
Use of ECLA
+∞
12.6
12
*
V03AE02
ATC
sevelamer; oral
+∞
12.6
12
*
C02KX01
ATC
bosentan; oral
+∞
12.6
12
*
E84.9
ICD-10 Finland
Cystic fibrosis, unspecified
137.3
12.6
13
*
J01XB01
ATC
colistin; inhalant, parenteral
137.3
12.6
13
*
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
39.9
12.4
15
*
GD1LA
NOMESCO Finland
GD
28.5
12.2
16
6
Z49.0
ICD-10 Finland
Preparatory care for dialysis
28.5
12.2
16
6
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
28.5
12.2
16
6
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
8.1
12.1
27
37
J05AB11
ATC
valaciclovir; oral
4.2
11.8
48
137
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
20.3
11.8
17
9
G04BE03
ATC
sildenafil; oral
20.3
11.8
17
9
UDH02
NOMESCO Finland
Rhinopharyngoscopy
6.0
11.8
33
63
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
3.6
11.8
60
209
A12AA04
ATC
calcium carbonate; oral
14.7
11.7
19
14
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
+∞
11.6
11
*
348
Kela drug reimbursment
Roflumilast
+∞
11.6
11
*
2770A
ICD-9 Finland
Other and unspecified disorders of metabolism, Cystic fibrosis
+∞
11.6
11
*
L01XE31
ATC
[U] nintedanib; oral
126.1
11.5
12
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.6
11.5
41
103
WX002
NOMESCO Finland
Sedation and analgesia
3.3
11.4
68
264
N03AX16
ATC
pregabalin; oral
3.1
11.3
75
315
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
8.1
11.3
25
34
TK810
NOMESCO Finland
Hemofiltration
45.7
11.0
13
*
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
45.7
11.0
13
*
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
6.7
11.0
28
47
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
22.8
10.8
15
7
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.7
10.8
98
500
EBA10
NOMESCO Finland
Surgical removal of tooth
3.7
10.6
49
156
J01MA02
ATC
ciprofloxacin; systemic
2.7
10.5
98
507
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
20.0
10.4
15
8
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
20.0
10.4
15
8
3AC01
NOMESCO Finland
NA
20.0
10.4
15
8
B02.9
ICD-10 Finland
Zoster without complication
5.6
10.3
30
60
I50.9
ICD-10 Finland
Heart failure, unspecified
4.7
10.3
35
84
A09AA02
ATC
multienzymes (lipase, protease etc.)
15.5
10.2
16
11
R03BA02
ATC
budesonide; inhalant
3.3
10.1
58
216
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.5
10.0
49
164
D70.82
ICD-10 Finland
Drug-induced neutropenia
21.2
9.9
14
7
J01DB01
ATC
cefalexin; oral
3.2
9.8
194
1500
Z94.9
ICD-10 Finland
Transplanted organ and tissue status, unspecified
57.5
9.7
11
*
J45.0
ICD-10 Finland
Predominantly allergic asthma
4.4
9.7
36
94
R03AC03
ATC
terbutaline; inhalant
3.5
9.6
48
163
N17.9
ICD-10 Finland
Acute renal failure, unspecified
7.5
9.6
22
32
J01AA02
ATC
doxycycline; systemic
2.8
9.6
181
1348
602
Kela drug reimbursment
Children's severe malnutrition
18.5
9.5
14
8
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
13.1
9.5
16
13
R28
ICPC
Limited function/disability (R)
13.1
9.5
16
13
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
4.0
9.5
39
112
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
31.5
9.5
12
*
J02AC03
ATC
voriconazole; systemic
31.5
9.5
12
*
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
31.5
9.5
12
*
E84.8
ICD-10 Finland
Cystic fibrosis with other manifestations
104.2
9.5
10
*
J43.1
ICD-10 Finland
Panlobular emphysema
104.2
9.5
10
*
TQW99
NOMESCO Finland
Other minor procedure on skin
7.9
9.5
21
29
B01AC11
ATC
iloprost; inhalant, parenteral
+∞
9.4
9
*
E84.1
ICD-10 Finland
Cystic fibrosis with intestinal manifestations
+∞
9.4
9
*
GX1K5
NOMESCO Finland
Diffusion capacity
+∞
9.4
9
*
RS310
NOMESCO Finland
NA
+∞
9.4
9
*
SPAT1262
SPAT
Handing over of treatment supplies
3.0
9.3
59
238
M01AH05
ATC
etoricoxib; oral
0.4
9.2
51
976
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
16.5
9.2
14
9
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
38.3
9.1
11
*
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
38.3
9.1
11
*
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
38.3
9.1
11
*
L57.0
ICD-10 Finland
Actinic keratosis
5.0
9.1
29
65
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
25.2
9.0
12
5
K05.30
ICD-10 Finland
Periodontitis complex
3.4
8.9
46
160
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
3.4
8.9
45
154
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.4
8.8
45
155
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.5
8.8
31
77
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
52.0
8.7
10
*
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
52.0
8.7
10
*
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
52.0
8.7
10
*
JN3AD
NOMESCO Finland
Abdominal CT examination
4.3
8.7
32
83
V03AE01
ATC
polystyrene sulfonate; oral
17.1
8.7
13
8
J47
ICD-10 Finland
Bronchiectasis
17.1
8.7
13
8
6BA02
NOMESCO Finland
NA
17.1
8.7
13
8
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
17.1
8.7
13
8
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.4
8.6
115
693
J05AB01
ATC
aciclovir; systemic
2.9
8.6
57
233
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
21.0
8.6
12
6
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
28.7
8.6
11
*
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
6.3
8.5
22
38
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
4.8
8.5
28
65
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
13.5
8.5
14
11
N18.0
ICD-10 Finland
End-stage renal disease
13.5
8.5
14
11
N17.8
ICD-10 Finland
Other acute renal failure
13.5
8.5
14
11
QB9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in torso, unspecified
93.4
8.5
9
*
J84.0
ICD-10 Finland
Alveolar and parietoalveolar conditions
93.4
8.5
9
*
UJF32
NOMESCO Finland
Coloscopy
2.7
8.5
67
306
WZC30
NOMESCO Finland
Teaching
3.2
8.4
47
172
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
4.9
8.4
27
61
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.8
8.4
59
250
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
4.2
8.4
32
86
JD1FN
NOMESCO Finland
Scintigraphy of gastric function
+∞
8.4
8
*
L04AA05
ATC
[U] tacrolimus; systemic
+∞
8.4
8
*
GX1D5
NOMESCO Finland
Flow volume spirometry
+∞
8.4
8
*
WX721
NOMESCO Finland
Oxygen concentrator therapy
+∞
8.4
8
*
115
NOMESCO Finland
NA
+∞
8.4
8
*
R03DX07
ATC
roflumilast; oral
+∞
8.4
8
*
XG460
NOMESCO Finland
Short time oxymetry
15.2
8.3
13
9
J45.1
ICD-10 Finland
Nonallergic asthma
4.3
8.3
30
77
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
12.3
8.2
14
12
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.7
8.2
27
63
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
10.6
8.2
15
15
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
34.7
8.1
10
*
XW000
NOMESCO Finland
Bone marrow biopsy
6.1
8.1
21
37
KA1AE
NOMESCO Finland
Kidney ultrasound examination
8.3
8.0
17
22
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
3.8
8.0
34
101
R99
ICPC
Respiratory disease other
13.7
8.0
13
10
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
13.7
8.0
13
10
ZXA05
NOMESCO Finland
Left side
2.6
7.9
66
310
V03AG01
ATC
sodium cellulose phosphate; systemic
46.6
7.8
9
*
L03AA02
ATC
filgrastim; parenteral
8.5
7.7
16
20
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.4
7.7
81
430
R05CB01
ATC
acetylcysteine; inhalant, oral
12.4
7.7
13
11
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
19.2
7.7
11
6
K06.18
ICD-10 Finland
Another gingival hyperplasia
19.2
7.7
11
6
ZXC50
NOMESCO Finland
Cryotherapy
9.4
7.7
15
17
J01FA06
ATC
roxithromycin; oral
2.3
7.6
95
545
XJC00
NOMESCO Finland
Oesophageal manometry
26.0
7.6
10
*
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
26.0
7.6
10
*
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
3.7
7.6
33
100
A41.9
ICD-10 Finland
Sepsis, unspecified
6.9
7.6
18
28
WX722
NOMESCO Finland
PEEP
5.3
7.5
22
45
HA1AA
NOMESCO Finland
X-ray mammography
4.6
7.5
25
59
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
14.0
7.5
12
9
I27.8
ICD-10 Finland
Other specified pulmonary heart diseases
82.7
7.5
8
*
XX7LW
NOMESCO Finland
NA
82.7
7.5
8
*
B34.9
ICD-10 Finland
Viral infection, unspecified
7.3
7.4
17
25
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.4
7.4
36
119
N02BE01
ATC
paracetamol; systemic, rectal
2.7
7.4
192
1547
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
+∞
7.3
7
*
ZX196
NOMESCO Finland
NA
+∞
7.3
7
*
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
8.4
7.2
15
19
J12.8
ICD-10 Finland
Other viral pneumonia
31.1
7.2
9
*
EB1WA
NOMESCO Finland
NA
20.8
7.2
10
5
UJC12
NOMESCO Finland
Flexible oesophagoscopy
20.8
7.2
10
5
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
20.8
7.2
10
5
J96.0
ICD-10 Finland
Acute respiratory failure
12.6
7.2
12
10
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
12.6
7.2
12
10
K65.0
ICD-10 Finland
Acute peritonitis
12.6
7.2
12
10
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
12.6
7.2
12
10
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
10.5
7.1
13
13
D64.9
ICD-10 Finland
Anaemia, unspecified
4.1
7.1
27
73
TFP20
NOMESCO Finland
Cardiodefibrillation
4.1
7.1
27
73
R03BA05
ATC
fluticasone; inhalant
2.6
7.0
53
235
J01FF01
ATC
clindamycin; systemic
2.3
7.0
73
383
R05CB02
ATC
bromhexine; systemic
14.4
7.0
11
8
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
14.4
7.0
11
8
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
9.8
6.9
13
14
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
5.2
6.9
20
41
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.8
6.9
48
201
I20.99
ICD-10 Finland
Angina pectoris, unspecified
4.5
6.8
23
55
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
5.5
6.8
19
37
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
5.5
6.8
19
37
V03AE03
ATC
lanthanum carbonate; oral
41.3
6.8
8
*
RK250
NOMESCO Finland
NA
41.3
6.8
8
*
XG467
NOMESCO Finland
Nocturnal CO2 monitoring
41.3
6.8
8
*
XF622
NOMESCO Finland
Measurement of minute volume of heart
41.3
6.8
8
*
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
41.3
6.8
8
*
K23.8*B37.8
ICD-10 Finland
Esophagitis caused by candidiasis
41.3
6.8
8
*
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
41.3
6.8
8
*
H25.1
ICD-10 Finland
Senile nuclear cataract
3.0
6.8
41
156
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.2
6.7
37
132
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.6
6.7
30
93
A07AA09
ATC
vancomycin; oral
12.8
6.6
11
9
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
9.1
6.6
13
15
J45.8
ICD-10 Finland
Mixed asthma
9.1
6.6
13
15
K03.66
ICD-10 Finland
Tooth plaque
3.7
6.6
28
83
R4130
NOMESCO Finland
Speech therapy
7.2
6.6
15
22
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.1
6.6
112
725
K29.7
ICD-10 Finland
Gastritis, unspecified
6.5
6.6
16
26
R04.2
ICD-10 Finland
Haemoptysis
6.5
6.6
16
26
N05CF01
ATC
zopiclone; oral
2.3
6.5
72
383
C01AA05
ATC
digoxin; systemic
5.2
6.5
19
39
GDA10
NOMESCO Finland
Biopsy of lung
71.8
6.5
7
*
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
14.9
6.5
10
7
C02CA01
ATC
prazosin; oral
14.9
6.5
10
7
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
14.9
6.5
10
7
XFE00
NOMESCO Finland
Epicardial ultrasonography
8.5
6.4
13
16
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.1
6.4
99
615
H65.3
ICD-10 Finland
Chronic mucoid otitis media
9.7
6.4
12
13
N19
ICD-10 Finland
Unspecified kidney failure
7.4
6.3
14
20
3A149
NOMESCO Finland
NA
+∞
6.3
6
*
KAC00
NOMESCO Finland
Nephrectomy
+∞
6.3
6
*
GCA18
NOMESCO Finland
Bronchoscopic dilatation of bronchus
+∞
6.3
6
*
B01AC21
ATC
treprostinil; parenteral
+∞
6.3
6
*
Y83.0
ICD-10 Finland
Surgical operation with transplant of whole organ as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
+∞
6.3
6
*
J93.0
ICD-10 Finland
Spontaneous tension pneumothorax
+∞
6.3
6
*
334
Kela drug reimbursment
Treprostinil
+∞
6.3
6
*
742
NOMESCO Finland
NA
+∞
6.3
6
*
C02KX04
ATC
macitentan; oral
+∞
6.3
6
*
JC2FN
NOMESCO Finland
Scintigraphy of oesophageal function
+∞
6.3
6
*
I50.0
ICD-10 Finland
Congestive heart failure
6.1
6.3
16
28
R03AC12
ATC
salmeterol; inhalant
6.1
6.3
16
28
XX2XT
NOMESCO Finland
Other injection with other radiological guidance
27.5
6.3
8
*
XG404
NOMESCO Finland
Peak expiratory flow (PEF) measurement
27.5
6.3
8
*
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
5.2
6.2
18
37
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.6
6.2
47
207
F43.29
ICD-10 Finland
Adaptation disorder UNS
7.0
6.1
14
21

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
189
34
221.99
307.65
5.6
1.6
—
—
—
0
0
189
34
221.99
307.65
5.6
1.6
—
—
—
0
0
189
34
221.99
307.65
5.6
1.6
—
—
—
0
0
189
34
221.99
307.65
5.6
1.6
—
—
—
0
0
234
187
170.99
282.32
38.1
10.9
10.2
8.7
mmol/l
1.84
234
180
232
272
100.47
221.48
20.4
8.7
1.1
1.1
mmol/l
0.71
232
256
122
32
73.24
210.40
4.5
2.7
—
—
—
0
0
177
147
38.45
200.24
4.5
1.5
—
—
—
0
0
210
248
46.72
195.38
34.6
8.5
105.2
103.7
mmol/l
3.74
210
241
164
8
587.69
186.52
4.3
1.4
35.1
71.1
ug/l
—
164
8
93
10
147.15
184.71
1.0
1.0
—
—
—
0
0
93
10
147.15
184.71
1.0
1.1
—
—
—
0
0
230
356
66.27
178.32
38.7
4.3
0.8
0.8
mmol/l
5.20
230
336
206
270
37.98
177.09
8.9
1.4
—
—
—
0
0
123
63
37.32
170.42
1.6
1.5
—
—
—
0
0
187
222
30.11
169.68
6.7
1.4
—
—
—
0
0
129
78
32.97
166.62
7.7
2.3
394.4
291.9
ug/l
0.52
129
72
97
26
60.18
164.28
1.1
1.2
—
—
—
0
0
100
32
51.28
161.58
1.2
1.2
—
—
—
0
0
100
32
51.28
161.58
2.3
2.4
—
—
—
0
0
117
60
35.65
161.45
1.5
1.5
103.4
84.9
u/ml
—
13
10
206
324
30.89
153.36
7.4
2.0
—
—
—
0
0
98
35
45.29
152.92
1.3
1.3
—
—
—
0
0
115
65
31.81
151.90
1.2
1.5
412.9
214.7
u/ml
4.14
88
35
207
335
30.54
150.63
9.5
2.8
0.8
2.0
e6/l
1.79
179
187
91
39
36.04
132.80
1.3
1.3
4.0
5.6
u/ml
0.31
43
18
191
326
21.33
130.25
8.0
2.6
29.7
29.5
s
0.16
191
318
117
93
22.69
129.98
1.3
1.5
—
—
—
0
0
118
9
244.96
123.16
4.3
4.9
—
—
—
0
0
137
160
17.65
120.33
2.8
2.5
35.8
9.2
ug/l
12.69
137
140
232
571
41.46
117.38
19.5
4.6
7.4
7.4
ph
1.72
46
112
222
527
28.80
114.75
19.6
4.4
100.3
91.4
%
5.23
222
521
197
402
19.13
114.48
10.6
2.7
548.3
585.9
mosm/kgh2o
1.50
191
345
227
571
32.12
111.22
15.8
2.9
—
—
—
0
0
203
457
19.00
107.68
4.1
1.5
2.1
2.5
g/l
2.21
194
284
227
591
30.71
107.09
16.1
3.0
0.1
0.4
e6/l
2.09
215
447
216
541
22.46
104.32
30.3
7.7
—
—
—
0
0
160
278
14.12
103.56
5.3
2.7
18.9
23.5
%
3.18
148
242
180
367
14.80
102.31
9.4
2.7
0.2
1.0
e6/l
5.05
160
218
228
646
28.60
97.83
18.0
3.1
7.7
144.6
e6/l
0.79
219
506
73
44
22.98
91.16
2.6
2.5
120.9
136.2
g/l
2.04
17
35
107
128
13.83
89.98
7.8
3.5
142.8
180.3
ng/l
0.47
102
110
216
617
18.93
89.65
16.5
2.2
87.9
215.0
u/l
4.59
216
584
191
475
13.64
89.21
6.7
3.4
—
—
—
0
0
232
753
28.49
84.96
44.8
6.7
—
—
—
0
0
229
738
24.99
84.04
22.3
3.5
25.0
108.7
e6/l
0.83
220
537
112
162
11.68
81.20
1.6
1.6
—
—
—
0
0
198
559
13.04
80.57
10.4
4.8
—
—
—
0
0
113
184
10.35
73.83
42.7
10.2
—
—
—
0
0
123
229
9.57
71.42
37.8
8.7
1.6
1.2
mmol/l
0.54
112
188
194
595
10.95
70.49
5.0
3.5
73.4
170.6
mg/l
0.42
160
389
96
136
10.81
69.81
6.3
5.2
—
—
—
0
0
171
469
9.30
68.76
6.3
2.0
1.5
1.2
mg/l
0.58
150
362
111
192
9.57
68.37
12.6
5.3
0.6
0.8
%
0.37
63
65
241
967
38.46
67.38
49.5
8.4
1.2
1.2
mmol/l
2.58
234
824
195
629
10.41
66.34
5.3
4.2
12.3
10.1
mg/mmol
0.22
160
402
41
12
40.64
65.69
1.0
1.4
—
—
—
0
0
52
32
20.23
63.40
2.2
2.3
—
—
—
0
0
145
364
8.06
62.39
5.8
3.9
3570.9
436.0
ng/l
4.62
138
276
81
109
10.50
60.69
8.8
7.8
24.1
24.1
mmol/l
0.02
70
101
104
192
8.54
59.64
10.1
6.6
1.5
1.8
mmol/l
0.26
87
161
123
272
7.91
59.52
2.0
1.7
—
—
—
0
0
121
265
7.89
59.04
2.8
1.6
—
—
—
0
0
163
500
7.45
55.80
5.2
2.5
—
—
—
0
0
231
1005
17.30
55.01
48.2
9.9
0.0
0.0
e9/l
0.83
211
827
127
312
7.22
54.66
2.0
1.7
—
—
—
0
0
154
455
7.17
54.60
3.7
2.1
3.3
3.2
mg/l
0.25
148
393
93
176
7.81
51.39
11.9
5.2
0.6
0.3
%
1.88
42
48
200
791
8.52
50.79
8.0
3.2
—
—
—
0
0
201
821
8.27
48.52
18.6
8.1
1.2
1.1
inr
0.78
56
257
74
116
8.63
48.22
54.3
9.1
—
—
—
0
0
32
12
30.42
47.15
1.6
1.4
2310.4
1300.6
e6/l
—
23
7
178
668
6.72
46.57
5.7
2.5
—
—
—
0
0
198
821
7.69
46.20
5.0
2.0
—
—
—
0
0
87
170
7.30
46.19
12.9
5.6
0.0
0.0
%
0.80
48
51
30
10
33.94
45.84
1.6
1.5
145048.1
33838.0
e6/l
—
21
5
30
10
33.94
45.84
1.5
1.4
—
—
—
0
0
130
383
5.97
44.44
2.0
1.9
—
—
—
0
0
50
9
68.88
44.35
1.1
1.8
—
—
—
0
0
86
174
7.00
43.94
13.7
5.6
0.2
0.2
%
0.00
57
57
30
12
28.26
43.14
1.5
1.4
—
—
—
0
0
78
146
7.30
42.92
8.0
5.2
115.4
86.0
ng/l
1.69
69
133
98
235
6.20
41.79
7.1
3.3
1.8
1.8
%
0.04
98
217
52
63
10.15
41.40
5.5
3.3
—
—
—
0
0
112
317
5.57
39.34
1.9
1.4
398.8
409.7
titre
0.03
34
66
212
1022
7.91
39.20
11.0
3.4
0.0
0.0
estimate
0.00
51
206
32
19
19.16
39.10
6.5
3.5
—
—
—
0
0
212
1025
7.88
38.97
15.9
4.6
0.0
0.0
estimate
0.00
54
213
213
1039
7.94
38.61
10.9
3.4
0.0
0.0
estimate
0.00
54
205
100
261
5.71
38.45
4.6
3.8
5.9
10.0
umol/l
1.51
90
234
238
1314
16.66
37.15
23.3
3.8
1.9
175.2
e6/l
0.56
11
21
142
510
5.11
36.88
5.3
2.7
—
—
—
0
0
84
194
6.00
36.84
2.7
2.7
39.7
32.2
u/l
0.91
78
162
33
24
15.68
36.33
6.9
3.6
—
—
—
0
0
49
65
9.12
36.17
1.1
1.5
190.2
292.3
miu/ml
—
5
28
53
79
8.24
35.49
10.5
8.9
2.0
1.4
mg/l
4.21
53
74
78
183
5.73
33.33
3.3
3.1
65.9
73.4
e9/l
0.88
53
136
110
352
4.78
32.30
1.5
1.3
19.3
29.6
iu/ml
0.67
29
122
239
1426
15.14
31.36
23.0
3.9
—
—
—
0
0
52
87
7.28
31.24
2.1
2.3
1.6
1.5
g/l
0.29
47
76
190
984
4.83
27.82
9.6
4.2
—
—
—
0
0
23
14
17.98
27.50
1.6
1.9
—
—
—
0
0
65
153
5.38
27.27
1.6
2.9
61.2
66.9
g/l
4.74
60
145
32
8
45.49
26.54
1.7
1.8
—
—
—
0
0
30
31
10.86
26.41
10.7
2.3
—
—
—
0
0
73
207
4.56
24.23
1.9
1.4
—
—
—
0
0
31
38
9.17
24.04
6.9
3.8
56.5
57.4
%
0.14
31
38
64
165
4.86
23.91
1.2
1.7
—
—
—
0
0
27
5
60.19
23.57
1.1
1.0
—
—
—
0
0
30
37
9.07
23.13
6.2
3.1
4.0
4.3
e9/l
0.31
30
37
120
511
3.58
21.93
24.3
4.8
—
—
—
0
0
52
124
5.03
21.18
9.9
2.6
0.2
0.1
e6/l
0.44
52
119
50
116
5.13
21.02
1.6
1.2
—
—
—
0
0
27
33
9.05
20.91
5.1
3.0
—
—
—
0
0
30
44
7.61
19.99
13.2
3.6
2.9
2.3
mmol/l
0.45
20
28
30
44
7.61
19.99
13.2
3.6
5.3
5.0
kpa
0.87
30
44
30
44
7.61
19.99
13.2
3.6
8.6
8.7
kpa
0.12
30
44
222
1481
5.32
18.96
22.5
3.7
—
—
—
0
0
35
65
6.10
18.66
13.8
3.8
8.9
8.9
kpa
0.02
35
60
58
169
4.16
18.19
13.0
4.1
7.4
7.4
ph
0.84
12
17
18
15
12.85
17.99
1.7
3.4
10.8
14.7
%
—
10
9
128
622
3.16
17.97
1.9
1.4
—
—
—
0
0
18
16
12.04
17.29
1.4
1.3
—
—
—
0
0
78
290
3.45
17.02
1.3
1.3
—
—
—
0
0
27
42
7.08
17.02
12.1
3.9
—
—
—
0
0
36
75
5.44
16.96
12.3
5.2
—
—
—
0
0
68
233
3.63
16.82
2.9
1.5
—
—
—
0
0
54
159
4.05
16.61
12.3
4.6
1.2
1.2
mmol/l
0.14
54
143
33
66
5.61
16.23
1.5
1.2
—
—
—
0
0
90
376
3.17
16.10
1.8
1.6
506.0
446.0
pmol/l
0.98
81
318
25
38
7.20
16.07
6.8
6.1
63.8
67.6
%
0.32
25
38
23
32
7.81
15.95
11.3
4.1
—
—
—
0
0
31
60
5.75
15.77
1.4
1.2
—
—
—
0
0
221
1551
4.55
15.63
5.3
3.7
14.0
14.8
pmol/l
5.27
215
1406
24
39
6.70
14.48
5.5
2.4
16.0
17.7
%
0.95
16
19
14
12
12.30
13.64
2.1
2.8
—
—
—
0
0
22
36
6.60
13.16
8.7
4.0
—
—
—
0
0
138
799
2.62
12.59
5.7
3.6
67.1
37.2
ng/l
1.75
127
549
13
12
11.37
12.05
1.3
1.2
—
—
—
0
0
16
7
24.28
11.72
4.1
2.6
24.9
27.3
umol/l
—
16
7
40
121
3.74
11.67
1.5
2.4
—
—
—
0
0
22
44
5.38
10.73
7.3
6.6
—
—
—
0
0
40
132
3.42
10.20
12.9
4.4
—
—
—
0
0
69
311
2.68
10.17
1.7
1.6
1033.9
1208.1
nmol/l
0.93
61
244
102
561
2.38
9.78
12.3
3.5
0.0
0.0
estimate
0.50
51
205
12
5
25.08
8.99
1.0
1.2
—
—
—
0
0
19
39
5.19
8.99
1.4
1.9
—
—
—
0
0
241
2016
5.91
8.85
97.4
14.7
36.0
40.8
%
35.00
226
1531
24
61
4.24
8.83
11.8
4.2
4.0
3.8
mmol/l
1.43
19
55
12
6
20.90
8.55
2.8
6.3
—
—
—
0
0
13
19
7.16
8.52
1.4
9.5
9.9
11.8
%
1.19
13
19
20
46
4.64
8.31
1.3
1.2
—
—
—
0
0
15
27
5.85
8.12
1.3
1.2
—
—
—
0
0
116
716
2.15
8.05
2.0
1.9
95.9
95.2
pmol/l
0.05
64
371
15
28
5.63
7.83
1.1
1.2
—
—
—
0
0
43
848
0.41
6.96
3.0
2.8
—
—
—
0
0
10
14
7.40
6.74
2.4
1.4
0.1
0.2
e9/l
—
10
14
227
1912
2.96
6.42
8.2
4.3
1.9
1.9
mu/l
0.27
222
1753
9
5
18.59
6.31
1.3
1.0
—
—
—
0
0
10
16
6.47
6.00
1.7
1.6
—
—
—
0
0
94
589
1.95
5.84
10.6
2.9
—
—
—
0
0
47
230
2.28
5.58
40.1
18.3
2.0
1.4
inr
—
7
27
8
5
16.45
5.44
2.4
1.4
—
—
—
0
0
8
5
16.45
5.44
2.4
1.4
6.3
7.0
%
—
8
5
38
171
2.44
5.44
8.2
3.5
—
—
—
0
0
77
461
1.97
5.40
10.2
3.5
1.0
1.0
kg/l
—
5
66
15
39
4.03
5.34
1.1
2.2
—
—
—
0
0
21
71
3.14
5.12
1.1
1.2
—
—
—
0
0
15
41
3.83
5.00
1.7
2.1
—
—
—
0
0
23
84
2.91
4.93
6.5
5.9
0.4
0.3
g/l
0.29
16
46
29
121
2.58
4.85
12.8
4.8
24.4
25.0
mmol/l
0.53
29
114
16
47
3.57
4.83
1.3
1.8
0.4
0.9
g/l
0.93
11
39
17
54
3.30
4.58
3.0
3.4
—
—
—
0
0
0
109
0.00
4.31
0.0
1.6
—
—
—
0
0
37
187
2.15
4.04
14.0
3.3
—
—
—
0
0
7
236
0.28
3.83
1.4
1.4
—
—
—
0
0
48
276
1.91
3.69
1.4
1.2
—
—
—
0
0
9
17
5.45
3.54
1.6
1.6
—
—
—
0
0
8
14
5.86
3.36
1.0
1.0
—
—
—
0
0
77
525
1.67
3.32
1.5
2.8
0.5
0.7
ug/l
3.55
54
337
8
15
5.47
3.21
1.0
1.1
—
—
—
0
0
17
67
2.65
3.20
1.0
1.5
257.1
289.0
ug/g
—
8
41
23
106
2.29
3.14
2.0
2.3
—
—
—
0
0
8
16
5.13
3.07
1.4
1.8
12.1
11.1
umol/l
—
8
16
7
12
5.96
3.04
1.1
6.6
—
—
—
0
0
8
17
4.82
2.94
1.4
1.4
—
—
—
0
0
10
30
3.43
2.94
1.3
1.3
—
—
—
0
0
10
31
3.32
2.80
1.5
1.4
—
—
—
0
0
9
24
3.85
2.70
1.8
1.2
—
—
—
0
0
11
38
2.98
2.61
1.1
1.1
—
—
—
0
0
11
38
2.98
2.61
1.5
1.1
—
—
—
0
0
11
38
2.98
2.61
1.5
1.1
—
—
—
0
0
7
15
4.77
2.61
2.7
1.3
0.9
0.7
u/ml
—
7
8
7
15
4.77
2.61
1.7
1.9
0.9
1.0
g/l
—
7
15
5
7
7.26
2.56
1.2
1.0
1609.6
1555.6
miu/ml
—
5
7
115
905
1.50
2.55
3.2
4.5
1.4
2.0
ug/l
2.27
97
820
6
12
5.09
2.41
4.7
2.5
559.3
517.4
min
—
6
7
9
28
3.29
2.33
1.8
1.5
—
—
—
0
0
5
9
5.64
2.22
1.8
3.1
—
—
—
0
0
26
145
1.88
2.20
2.8
2.3
3.4
4.1
e9/l
1.06
19
117
6
15
4.07
2.05
4.0
2.5
804.2
645.8
ml
—
6
8
7
21
3.40
1.98
1.0
1.1
—
—
—
0
0
7
21
3.40
1.98
2.1
3.3
—
—
—
0
0
16
78
2.12
1.95
1.7
1.2
—
—
—
0
0
33
206
1.69
1.95
2.5
4.7
19.7
42.1
ug/l
0.36
25
164
5
11
4.61
1.95
1.2
7.3
—
—
—
0
0
5
12
4.23
1.83
1.4
6.7
—
—
—
0
0
8
29
2.81
1.80
1.3
1.1
—
—
—
0
0
7
25
2.85
1.66
1.1
1.2
—
—
—
0
0
239
2281
2.00
1.56
48.3
13.0
—
—
—
0
0
5
15
3.38
1.53
1.2
1.3
—
—
—
0
0
9
37
2.48
1.49
4.4
1.5
—
—
—
0
0
13
67
1.99
1.41
4.2
2.6
—
—
—
0
0
9
41
2.24
1.38
1.1
1.0
—
—
—
0
0
75
607
1.34
1.26
7.3
3.7
—
—
—
0
0
6
25
2.43
1.25
1.0
1.2
—
—
—
0
0
6
25
2.43
1.25
2.5
1.7
11.3
18.7
ug/l
—
6
25
9
49
1.87
0.99
2.2
2.2
1217.2
2370.3
e6/l
—
9
40
9
49
1.87
0.99
2.2
2.0
6.4
10.1
e6/l
—
9
39
0
29
0.00
0.98
0.0
1.3
—
61.7
—
0
8
0
29
0.00
0.98
0.0
1.1
—
3.2
—
0
13
10
54
1.89
0.98
1.1
2.1
1.4
3915.9
u/l
—
5
17
21
143
1.51
0.93
1.2
1.3
—
35.8
—
0
8
36
273
1.37
0.92
2.0
2.6
198.7
110.0
ug/g
0.71
31
223
33
247
1.39
0.91
1.6
1.3
—
—
—
0
0
14
88
1.63
0.86
4.1
1.6
—
—
—
0
0
6
31
1.96
0.85
1.3
1.0
—
—
—
0
0
27
201
1.38
0.78
19.2
4.9
—
—
—
0
0
0
27
0.00
0.78
0.0
1.1
—
10.0
—
0
14
22
158
1.43
0.77
2.3
2.5
—
19.7
—
0
8
59
496
1.25
0.74
1.4
1.3
0.4
1.3
u/ml
1.43
17
135
7
41
1.73
0.70
2.3
2.3
—
—
—
0
0
7
120
0.57
0.69
1.0
1.1
—
—
—
0
0
5
27
1.87
0.69
1.0
1.3
—
—
—
0
0
0
20
0.00
0.60
0.0
1.5
—
—
—
0
0
0
21
0.00
0.60
0.0
1.5
—
—
—
0
0
6
36
1.68
0.57
1.0
1.6
—
—
—
0
0
6
93
0.64
0.43
1.0
1.1
—
—
—
0
0
10
70
1.45
0.42
1.5
1.5
—
—
—
0
0
5
33
1.53
0.41
2.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
242.0
—
0
9
0
17
0.00
0.41
0.0
1.2
—
13872.2
—
0
12
0
19
0.00
0.39
0.0
15.2
—
1325.8
—
0
19
9
70
1.30
0.37
15.1
12.1
—
—
—
0
0
11
81
1.37
0.37
1.0
1.4
—
—
—
0
0
11
82
1.36
0.34
1.0
1.4
—
—
—
0
0
11
83
1.34
0.32
1.0
1.4
—
—
—
0
0
11
83
1.34
0.32
1.0
1.4
—
—
—
0
0
7
55
1.28
0.30
4.6
3.9
—
—
—
0
0
8
62
1.30
0.28
1.0
1.4
—
—
—
0
0
16
132
1.23
0.26
4.4
2.1
—
—
—
0
0
5
74
0.67
0.26
1.0
1.8
—
—
—
0
0
9
77
1.18
0.24
1.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
2.4
—
5.7
—
0
11
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
10.8
—
0.6
—
0
14
20
227
0.87
0.19
1.1
1.5
—
—
—
0
0
38
350
1.10
0.17
1.3
1.3
24.7
9.2
u/ml
0.38
16
146
21
187
1.13
0.16
1.3
1.2
—
—
—
0
0
12
105
1.15
0.11
8.0
3.2
—
—
—
0
0
5
44
1.14
0.10
3.6
1.7
—
—
—
0
0
7
64
1.10
0.08
1.4
1.5
290.3
353.4
mu/l
—
7
59
11
112
0.98
0.00
1.2
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
6.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
0.00
1.2
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
6.7
—
7.6
—
0
9
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
1.9
—
0
5
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
21.8
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
5
56
0.89
0.00
1.2
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
154.3
—
0
6
0
7
0.00
0.00
0.0
1.6
—
17.3
—
0
7
0
6
0.00
0.00
0.0
1.2
—
48.3
—
0
6
0
7
0.00
0.00
0.0
3.1
—
1.6
—
0
7

Mortality – FinRegistry

↥

Association

Association between endpoint LUNG_TRANSPLANTATION and mortality.

Females

Parameter HR [95% CI] p-value
LUNG_TRANSPLANTATION 7.063 [4.68, 10.65] < 0.001
Birth year 0.995 [0.99, 1.0] 0.283

During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 232 females with LUNG_TRANSPLANTATION died.

Males

Parameter HR [95% CI] p-value
LUNG_TRANSPLANTATION 5.555 [3.44, 8.97] < 0.001
Birth year 0.984 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 119 out of 318 males with LUNG_TRANSPLANTATION died.

Mortality risk

Mortality risk for people of age

years, who have LUNG_TRANSPLANTATION.

N-year risk Females Males
1 0.661% 1.124%
5 4.172% 5.833%
10 10.491% 13.793%
15 18.406% 24.477%
20 29.987% 38.464%

Relationships between endpoints

↥

Index endpoint: LUNG_TRANSPLANTATION – Lung transplantation

GWS hits: 4

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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