This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

LUNG_TRANSPLANTATION

Lung transplantation

EFO Endpoint Browser

LUNG_TRANSPLANT

No definition available.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Operations: NOMESCO codes — ^GDG0[0\|3]\|^GDG[0\|3]\|^GDG96\|^FQB00\|^FQB[1\|2\|3]0 1 out of 7 registries used, show all original rules.	7
4. Check minimum number of events None	7
5. Include endpoints None	7
6. Filter based on genotype QC (FinnGen only)	7

Control definitions (FinnGen only)

Control exclude: COPD_INSUFFICIENCY

Extra metadata

First used in FinnGen datafreeze: DF2

NAME	LUNG_TRANSPLANT
CONTROL_EXCLUDE	COPD_INSUFFICIENCY
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM	^GDG0[0\|3]\|^GDG[0\|3]\|^GDG96\|^FQB00\|^FQB[1\|2\|3]0
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Lung transplantation based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Not enough data for upset plot.

Not enough data for upset table.

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	45	23	22
Only index persons	29	15	14
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	-	47.06	50.97
Only index persons	46.23	45.59	46.91

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	7	-	-
Unadjusted period prevalence (%)	0.00	-	-
Median age at first event (years)	33.62	-	-

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3010375) cycloSPORINE [Mass/volume] in Blood

+∞

9.38

29.7

0.0

100.7

—

ug/l

—

(3033658) Prothrombin time (PT) actual/Normal

+∞

4.68

18.1

3.7

84.0

104.4

—

(36304419) Bacteria [Presence] in Urine

+∞

3.84

11.1

3.1

—

(40758558) Short blood count panel - Blood

+∞

3.70

15.9

8.2

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

+∞

3.43

11.1

3.0

—

(3018095) Leukocytes [#/volume] in Urine

+∞

3.31

13.0

3.5

3.4

3.5

e6/l

—

(42870588) Differential panel, method unspecified - Blood

+∞

3.31

17.1

6.4

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

+∞

1.85

27.0

12.6

4.2

4.0

e9/l

—

(3044889) 12 lead EKG panel

+∞

1.81

10.4

3.0

—

(3037467) Urinalysis macro (dipstick) panel - Urine

+∞

1.41

15.3

4.1

—

(1761868) Lipid panel - Serum or Plasma

0.00

1.04

0.0

2.1

—

(3003338) MCHC [Mass/volume]

+∞

0.74

91.1

15.3

324.3

334.6

g/l

—

(3002385) Erythrocyte distribution width [Ratio]

+∞

0.74

90.3

12.3

14.4

13.3

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

0.00

0.72

0.0

2.2

—

(3019832) Treponema pallidum Ab [Presence] in Serum

0.00

0.48

0.0

2.1

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

0.00

0.48

0.0

1.7

—

(3009542) Hematocrit [Volume Fraction] of Blood

+∞

0.47

93.1

12.2

39.6

42.7

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

+∞

0.47

78.7

10.2

26.1

17.7

mg/l

—

(40760892) CBC W Ordered Manual Differential panel - Blood

0.00

0.23

0.0

3.8

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

0.00

0.23

0.0

1.1

—

1.6

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

+∞

0.23

90.0

10.5

77.7

72.0

umol/l

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

0.00

0.23

0.0

1.8

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.00

0.23

0.0

1.1

—

(21494755) Public health laboratory ask at order entry panel

0.00

0.23

0.0

1.3

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.00

0.23

0.0

1.4

—

(3013512) EKG study

0.00

0.23

0.0

1.5

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.00

0.0

2.3

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.00

0.0

5.6

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3001019) Free T4 and TSH panel - Serum or Plasma

0.00

0.0

1.2

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.0

1.4

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

0.00

0.0

1.0

—

(3011288) Drugs identified in Urine by Screen method

0.00

0.0

1.0

—

(40761536) Microorganisms panel - Urine sediment

0.00

0.0

2.8

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.0

1.6

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.00

0.0

2.4

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.00

0.0

1.0

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.2

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.00

0.0

1.3

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

0.00

0.0

1.3

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3019225) pH of Specimen

0.00

0.0

2.2

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.0

1.6

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint LUNG_TRANSPLANT and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have LUNG_TRANSPLANT.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: LUNG_TRANSPLANT – Lung transplantation

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Lung transplantation

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints