Stenosis and insufficiency of lacrimal passages

H7_STENOLACRI

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H04.5
  • Hospital discharge: ICD-9 3755
  • Hospital discharge: ICD-8 36802
  • Cause of death: ICD-10 H04.5
  • Cause of death: ICD-9 3755
  • Cause of death: ICD-8 36802

2 out of 7 registries used, show all original rules.

3760

4. Check minimum number of events

None

3760

5. Include endpoints

None

3760

6. Filter based on genotype QC (FinnGen only)

3760

Control definitions (FinnGen only)

Control exclude
H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H04
Name in latin
Stenosis et/sive insufficientia viarum lacrimalium

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 32019 21562 10334
Only index persons 27395 18897 8498
Unadjusted period prevalence (%)
Whole population 0.51 0.62 0.29
Only index persons 0.58 0.69 0.32
Median age at first event (years)
Whole population 53.81 56.82 47.43
Only index persons 53.93 56.56 48.06

-FinnGen-

Key figures

All Female Male
Number of individuals 3760 2709 1051
Unadjusted period prevalence (%) 0.79 0.92 0.46
Median age at first event (years) 58.72 57.37 62.21

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3350
Matched controls
33497
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
6.1
323.0
2193
7987
CCD50
NOMESCO Finland
Dacryocystorhinostomy with insertion of tube
+∞
323.0
310
*
CCD60
NOMESCO Finland
Transnasal dacryocystorhinostomy
2641.3
323.0
479
*
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
888.1
323.0
1047
17
TCC30
NOMESCO Finland
Intubation of lacrimal canaliculus/duct
3592.3
323.0
855
*
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
16384.0
323.0
3005
14
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
971.9
323.0
498
6
H04.10
ICD-10 Finland
Dry eye syndrome
11.3
306.0
612
647
H04.4
ICD-10 Finland
Chronic inflammation of lacrimal passages
+∞
294.2
278
*
H04.2
ICD-10 Finland
Epiphora
262.3
284.4
288
12
H04.3
ICD-10 Finland
Acute and unspecified inflammation of lacrimal passages
246.5
267.5
272
12
36802
ICD-8 Finland
Inflammation of lachrymal glands and ducts, Obstructio, stenosis viarum lacrimalium
+∞
228.8
217
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.2
217.2
1914
9871
CCA20
NOMESCO Finland
Incision of lacrimal punctum or canaliculus
435.8
207.7
206
5
3755A
ICD-9 Finland
Disorders of lachrymal system, Stenosis and insufficiency of lachrymal passages
+∞
193.6
184
*
H02.3
ICD-10 Finland
Blepharochalasis
73.9
188.5
215
31
UDH02
NOMESCO Finland
Rhinopharyngoscopy
6.4
170.9
489
873
CCD30
NOMESCO Finland
Reconstruction of lacrimal canaliculus
1124.9
112.2
109
*
H02.1
ICD-10 Finland
Ectropion of eyelid
249.6
95.1
97
*
S01GX01
ATC
cromoglicic acid; ophthalmic
2.6
90.0
820
3761
F03
ICPC
Eye discharge
4.4
86.9
341
842
H04.0
ICD-10 Finland
Dacryoadenitis
88.9
85.4
95
11
CCD40
NOMESCO Finland
Percutaneous dacryocystorhinostomy
+∞
84.7
81
*
H02.4
ICD-10 Finland
Ptosis of eyelid
28.3
78.0
107
39
CBB11
NOMESCO Finland
Resection of lax skin in upper eyelid
391.2
77.1
77
*
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
10.4
77.0
155
155
3317
FHL
Transcutaneous dacryocystorinostomy (Toti)
733.9
73.5
72
*
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
89.9
71.2
79
9
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
4.0
65.8
284
761
H01.0
ICD-10 Finland
Blepharitis
4.8
64.3
225
491
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
117.4
64.1
69
6
UDM02
NOMESCO Finland
Sinoscopy
6.9
59.7
155
235
H10
ICD-10 Finland
Conjunctivitis
3.7
59.6
280
806
S01AX11
ATC
[U] ofloxacin; ophthalmic
4.5
56.5
210
487
ZXA10
NOMESCO Finland
Bilateral
2.1
55.2
706
3703
3329
FHL
Other measure in this category
546.6
54.7
54
*
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
3.5
54.3
268
802
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
3.7
52.4
248
717
WX002
NOMESCO Finland
Sedation and analgesia
2.1
51.2
727
3969
CCC99
NOMESCO Finland
Other operation on lacrimal passages
505.3
50.5
50
*
J01DB01
ATC
cefalexin; oral
1.9
49.8
2669
22621
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.2
48.2
590
3017
R01AD09
ATC
mometasone; nasal
1.7
47.1
1458
10365
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.5
43.5
363
1529
CC1CB
NOMESCO Finland
Dacryocystography
+∞
42.8
41
*
R01AD08
ATC
fluticasone; nasal
1.8
42.4
938
5958
ZXA05
NOMESCO Finland
Left side
1.8
41.8
909
5740
F29
ICPC
Eye symptom/complaint other
2.6
41.0
317
1280
R01AD12
ATC
fluticasone furoate; nasal
1.8
40.5
938
6029
WX110
NOMESCO Finland
Local anesthesy
1.6
38.8
2145
17487
ZXA00
NOMESCO Finland
Right side
1.7
38.0
932
6076
3312
FHL
Probing under general anesthesia
134.9
37.8
40
*
S01GX08
ATC
ketotifen; ophthalmic
3.8
36.9
161
434
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.5
34.5
281
1163
J01AA02
ATC
doxycycline; systemic
1.6
32.5
2485
21437
J01FA10
ATC
azithromycin; systemic
1.5
30.7
1784
14305
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
58.9
30.1
35
6
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
34.0
28.7
37
11
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
4.3
28.4
107
253
S01XA18
ATC
ciclosporin; ophthalmic
21.8
28.2
41
19
H02AB06
ATC
prednisolone; systemic
1.5
27.3
1451
11286
CBF99
NOMESCO Finland
Other operation for ectropion
+∞
27.1
26
*
M03BX02
ATC
tizanidine; oral
1.5
26.8
1835
15051
N02BE01
ATC
paracetamol; systemic, rectal
1.6
26.3
2774
25010
SPAT1153
SPAT
Removal of sutures
1.6
26.3
994
7142
S01AA01
ATC
chloramphenicol; ophthalmic (antibiotics)
2.6
26.2
194
760
H57.1
ICD-10 Finland
Ocular pain
3.8
25.9
113
306
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.7
25.8
601
3796
R06AE07
ATC
cetirizine; oral
1.5
25.7
1345
10382
H00.1
ICD-10 Finland
Chalazion
5.1
25.6
82
164
Q10.5
ICD-10 Finland
Congenital stenosis and stricture of lacrimal duct
44.6
25.5
31
7
H10.4
ICD-10 Finland
Chronic conjunctivitis
8.6
25.2
55
65
A02BC02
ATC
pantoprazole; systemic
1.5
25.1
2033
17151
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
25.1
1078
7958
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.0
24.8
356
1908
CBN99
NOMESCO Finland
Other operation on eyelid for malposition
252.0
24.7
25
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
24.5
656
4300
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
+∞
24.0
23
*
M01AH05
ATC
etoricoxib; oral
1.4
23.4
1730
14232
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.6
23.4
181
729
S18
ICPC
Laceration/cut
1.5
23.3
1262
9746
A02BC05
ATC
esomeprazole; systemic
1.5
23.3
1242
9563
A02BC03
ATC
lansoprazole; oral
1.5
23.1
920
6650
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
3.9
22.7
95
249
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
22.4
651
4347
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
22.0
806
5701
J01DA01
ATC
[U] cefalexin; systemic
1.4
22.0
1925
16270
3754A
ICD-9 Finland
Disorders of lachrymal system, Chronic inflammation of lachrymal passages
+∞
21.9
21
*
3320
FHL
Channel chorostomy
+∞
21.9
21
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
21.7
883
6392
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
21.2
1196
9268
J31.0
ICD-10 Finland
Chronic rhinitis
2.1
21.1
241
1176
J01CA04
ATC
amoxicillin; systemic
1.5
21.0
2509
22411
CBF10
NOMESCO Finland
Shortening of canthal ligaments and tarsal plate for ectropion
+∞
20.8
20
*
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
20.7
911
6700
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
6.5
20.5
53
82
R06AX27
ATC
desloratadine; oral
1.5
20.5
766
5427
N03AX12
ATC
gabapentin; oral
1.7
20.4
468
2924
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
20.1
1491
12134
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.9
20.0
121
421
R01BA52
ATC
pseudoephedrine, combinations; oral
1.5
19.8
946
7062
36804
ICD-8 Finland
Inflammation of lachrymal glands and ducts, Dacryocystitis chronica
+∞
19.8
19
*
S01GX02
ATC
levocabastine; ophthalmic
2.2
19.7
200
924
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
19.6
770
5514
CBB00
NOMESCO Finland
Excision of chalazion
21.7
19.5
28
13
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
19.4
798
5767
M01AC06
ATC
meloxicam; systemic, rectal
1.4
19.4
1129
8765
J02AC01
ATC
fluconazole; systemic
1.4
19.2
1238
9790
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.9
19.2
307
1707
R42
ICD-10 Finland
Dizziness and giddiness
1.5
19.1
684
4789
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.7
18.8
407
2499
M02AA07
ATC
piroxicam; topical
1.4
18.6
1143
8947
H04.6
ICD-10 Finland
Other changes in lacrimal passages
191.0
18.5
19
*
CBJ30
NOMESCO Finland
Plastic repair of levator aponeurosis of eyelid
191.0
18.5
19
*
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
191.0
18.5
19
*
D07AB02
ATC
hydrocortisone butyrate; topical
1.5
18.4
831
6117
J34.2
ICD-10 Finland
Deviated nasal septum
2.5
18.0
145
598
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
18.0
1047
8099
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
17.7
17
*
H04
ICD-10 Finland
Disorders of lacrimal system
66.9
17.7
20
*
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.5
17.6
664
4695
E0000UV
ATC
NA
1.4
17.6
1186
9413
CCD99
NOMESCO Finland
Other reconstructive operation on lacrimal apparatus
180.9
17.5
18
*
CBN30
NOMESCO Finland
Shortening of canthal ligament
180.9
17.5
18
*
M54.5
ICD-10 Finland
Low back pain
1.4
17.2
934
7117
M79.6
ICD-10 Finland
Pain in limb
1.4
17.1
1050
8178
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.4
17.1
1546
12891
DJD20
NOMESCO Finland
Plastic repair of septum of nose
2.9
16.9
103
361
R51.80
ICD-10 Finland
Headache
1.6
16.7
417
2660
CCA30
NOMESCO Finland
Incision of lacrimal sac
+∞
16.7
16
*
A98
ICPC
Health maint/preventive medicine
1.7
16.6
3096
29370
R03DC03
ATC
montelukast; oral
1.6
16.5
468
3088
3316
FHL
Teardrop plastic or reconstruction
170.8
16.5
17
*
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.2
16.5
168
781
J01FA06
ATC
roxithromycin; oral
1.4
16.4
1189
9527
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
16.4
1263
10228
L03
ICPC
Low back symptom/complaint
1.5
16.2
702
5103
D07AC01
ATC
betamethasone; topical
1.4
16.2
975
7554
M70.6
ICD-10 Finland
Trochanteric bursitis
1.6
16.1
402
2560
M31.3
ICD-10 Finland
Wegener granulomatosis
10.8
15.9
30
28
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.8
15.9
285
1644
S01KA02
ATC
hypromellose; ophthalmic
3.2
15.8
82
258
S01ED51
ATC
timolol, combinations; ophthalmic
1.9
15.7
245
1352
CCD70
NOMESCO Finland
Conjunctivocystorhinostomy with insertion of tube
+∞
15.6
15
*
CBG00
NOMESCO Finland
Epilation of cilia by electrolysis
160.7
15.5
16
*
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
15.0
1246
10169
S01GX05
ATC
lodoxamide; ophthalmic
3.9
14.9
60
154
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
14.8
775
5834
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.6
14.8
109
431
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
14.7
1302
10723
H02AB04
ATC
methylprednisolone; systemic
1.6
14.7
425
2811
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
14.7
2027
17872
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.9
14.6
223
1219
R06AE09
ATC
levocetirizine; oral
1.6
14.2
401
2634
J05AB01
ATC
aciclovir; systemic
1.5
14.1
596
4297
H02.2
ICD-10 Finland
Lagophthalmos
30.1
13.9
18
6
R01AD01
ATC
beclometasone; nasal
1.5
13.8
443
3005
R05
ICD-10 Finland
Cough
1.5
13.8
559
3991
XCK00
NOMESCO Finland
Perimetry
1.9
13.7
211
1157
G44.2
ICD-10 Finland
Tension-type headache
1.6
13.6
369
2399
114
Kela drug reimbursment
Glaucoma
1.7
13.6
280
1685
3318
FHL
Transnasal dacryocystorinostomy (West-Halle)
+∞
13.5
13
*
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.6
13.5
389
2570
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
13.5
483
3359
R03AC02
ATC
salbutamol; inhalant
1.3
13.5
1518
12910
SPAT1312
SPAT
General health counselling
1.4
13.5
954
7555
CBF20
NOMESCO Finland
Resection of part of tarsus for ectropion
140.5
13.5
14
*
S01GX09
ATC
olopatadine; ophthalmic
2.8
13.4
84
302
N06AX11
ATC
mirtazapine; oral
1.4
13.4
908
7138
L13
ICPC
Hip symptom/complaint
1.5
13.3
477
3318
M25.5
ICD-10 Finland
Pain in joint
1.4
13.3
781
5990
M01AX17
ATC
nimesulide; oral
1.4
13.2
736
5586
WX199
NOMESCO Finland
Other local analgesia
2.7
13.2
87
322
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
13.1
1830
16022
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.4
13.1
655
4872
H00.03
ICD-10 Finland
Preseptal cellulite in the eyelid
15.1
13.1
21
14
R05FA02
ATC
opium derivatives and expectorants; systemic
1.3
13.0
1194
9837
M01AX05
ATC
glucosamine; oral
1.4
12.9
660
4929
D06BX01
ATC
metronidazole; topical
1.6
12.9
307
1930
CBJ50
NOMESCO Finland
Operation for ptosis of eyebrow
50.2
12.8
15
*
S01AX12
ATC
[U] norfloxacin; ophthalmic
6.9
12.8
31
45
L57.0
ICD-10 Finland
Actinic keratosis
1.7
12.8
299
1869
R06AX22
ATC
ebastine; oral
1.5
12.8
474
3318
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
7.2
12.7
30
42
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
12.7
1055
8552
M01AE02
ATC
naproxen; oral, rectal
1.3
12.6
1640
14181
H16.0
ICD-10 Finland
Corneal ulcer
2.3
12.6
113
497
R52.9
ICD-10 Finland
Pain, unspecified
1.8
12.5
236
1388
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.0
12.5
149
744
L15
ICPC
Knee symptom/complaint
1.4
12.4
615
4561
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
2.3
12.3
114
510
UDC00
NOMESCO Finland
Ear microscopy
1.8
12.2
212
1209
L08
ICPC
Shoulder symptom/complaint
1.5
12.2
538
3899
M79.1
ICD-10 Finland
Myalgia
1.6
12.2
345
2268
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.7
12.2
245
1467
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
2.4
12.2
99
415
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.3
12.1
912
7268
SPAT1263
SPAT
Sampling
1.3
12.0
1256
10507
N02AX02
ATC
tramadol; systemic, rectal
1.3
12.0
1172
9711
SPAT1301
SPAT
No procedures
1.3
11.9
941
7553
S01AA13
ATC
fusidic acid; ophthalmic
2.6
11.9
87
344
CA1BD
NOMESCO Finland
Extensive orbita CT
46.8
11.9
14
*
D07AC13
ATC
mometasone; topical
1.4
11.8
806
6320
R06AX26
ATC
fexofenadine; oral
1.9
11.8
179
979
L01
ICPC
Neck symptom/complaint
1.5
11.8
383
2599
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
11.8
1121
9251
SPAT1325
SPAT
Vaccination
1.3
11.7
1046
8543
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.3
11.7
112
506
J01MA02
ATC
ciprofloxacin; systemic
1.3
11.7
1092
8980
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.2
11.7
113
515
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.7
11.7
232
1383
UJF32
NOMESCO Finland
Coloscopy
1.4
11.7
735
5680
J01EA01
ATC
trimethoprim; systemic
1.4
11.7
808
6349
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.5
11.6
433
3030
H16.9
ICD-10 Finland
Keratitis, unspecified
3.8
11.6
48
128
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
2.7
11.6
78
295
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
11.6
750
5829
CBN20
NOMESCO Finland
Shortening of eyelid retractors
120.4
11.4
12
*
J01AA07
ATC
tetracycline; systemic
1.5
11.4
390
2679
J01AA04
ATC
lymecycline; systemic
1.6
11.4
339
2258
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
11.4
1155
9606
A02BA02
ATC
ranitidine; systemic
1.4
11.3
574
4274
F70
ICPC
Conjunctivitis infectious
2.7
11.3
75
281
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.6
11.2
264
1653
CBA10
NOMESCO Finland
Biopsy of eyelid
5.0
11.2
35
71
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.4
11.0
748
5850
M01AH02
ATC
rofecoxib; oral
1.5
11.0
391
2706
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
2.8
11.0
70
256
SDA01
NOMESCO Finland
Simple parodonthologic therapy
1.4
11.0
697
5393
H04.9
ICD-10 Finland
Disorder of lacrimal system, unspecified
43.4
10.9
13
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.6
10.9
325
2163
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
2.8
10.9
68
245
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
10.8
899
7252
M01AB05
ATC
diclofenac; systemic, rectal
1.3
10.7
1905
17011
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
10.7
600
4542
E000001
ATC
NA
1.4
10.7
573
4304
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
2.3
10.7
97
430
G04BD12
ATC
mirabegron; oral
1.6
10.6
289
1880
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
10.6
1069
8862
J01FF01
ATC
clindamycin; systemic
1.4
10.6
736
5776
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
10.6
494
3619
N03AX16
ATC
pregabalin; oral
1.4
10.5
644
4947
H26.4
ICD-10 Finland
After-cataract
1.6
10.5
271
1740
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
10.5
565
4246
H05.2
ICD-10 Finland
Exophthalmic conditions
+∞
10.4
10
*
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.4
10.4
501
3689
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
10.3
435
3123
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
10.3
448
3235
L17
ICPC
Foot/toe symptom/complaint
1.4
10.3
704
5507
P01AB01
ATC
metronidazole; oral, rectal
1.3
10.2
1120
9378
H20.1
ICD-10 Finland
Chronic iridocyclitis
4.0
10.2
39
98
F73
ICPC
Eye infection/inflammation other
3.2
10.1
52
166
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.1
10.1
111
537
XQ802
NOMESCO Finland
Epicutan test
2.1
10.1
113
551
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
10.1
263
1694
F13
ICPC
Eye sensation abnormal
2.5
10.0
75
301
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
10.0
1036
8599
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.6
10.0
271
1763
CBB21
NOMESCO Finland
Correction of lax skin and resection of herniated fat in upper eyelid
40.2
10.0
12
*
S01ED01
ATC
timolol; ophthalmic
2.1
9.9
114
562
H15.1
ICD-10 Finland
Episcleritis
3.6
9.9
43
121
F02
ICPC
Red eye
2.0
9.8
116
578
M54.2
ICD-10 Finland
Cervicalgia
1.7
9.8
192
1141
CB9S4
NOMESCO Finland
Photography of eyelids and eyebrows
26.1
9.8
13
5
SPAT1310
SPAT
Counselling related to known health issue
1.3
9.8
916
7498
N07CA01
ATC
betahistine; oral
1.7
9.8
212
1297
A03FA02
ATC
cisapride; oral, rectal
1.6
9.8
244
1553
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
1.8
9.7
163
923
J01FA09
ATC
clarithromycin; systemic
1.3
9.7
875
7123
H05.0
ICD-10 Finland
Acute inflammation of orbit
55.1
9.6
11
*
CAB00
NOMESCO Finland
Anterior orbitotomy with excision of lesion
55.1
9.6
11
*
H10.5
ICD-10 Finland
Blepharoconjunctivitis
3.3
9.6
47
145
S01AA30
ATC
combinations of different antibiotics; ophthalmic
4.7
9.6
31
66
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
9.6
2701
25400
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.7
9.6
205
1253
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
9.5
325
2231
DM1CI
NOMESCO Finland
Very extensive cone beam CT of paranasal sinus
15.1
9.5
15
10
S01AA03
ATC
neomycin; ophthalmic (antibiotics)
5.7
9.5
26
46
H16.2
ICD-10 Finland
Keratoconjunctivitis
5.7
9.5
26
46
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
5.7
9.5
26
46
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.5
9.5
326
2242
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.7
9.4
209
1289
K08.80
ICD-10 Finland
Toothache NOS
1.7
9.4
189
1133
H25.1
ICD-10 Finland
Senile nuclear cataract
1.3
9.4
743
5925
R03AC03
ATC
terbutaline; inhalant
1.5
9.4
376
2668
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
2.3
9.4
84
371
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
9.4
439
3210
R01AD05
ATC
budesonide; nasal
1.6
9.4
215
1337
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.6
9.4
218
1364
A01AB09
ATC
miconazole; local oral
1.6
9.4
263
1725
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.1
9.3
101
488
H10.8
ICD-10 Finland
Other conjunctivitis
4.5
9.2
31
69
LEF03
NOMESCO Finland
Posterior colporrpahy with sutures for primary rectocele
1.9
9.2
126
664
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.3
9.2
946
7829
N05CF01
ATC
zopiclone; oral
1.3
9.2
922
7603
J02AC02
ATC
itraconazole; systemic
1.4
9.2
493
3697
R03BA08
ATC
ciclesonide; inhalant
1.6
9.2
224
1419
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.0
9.2
115
588
N39.3
ICD-10 Finland
Stress incontinence
1.6
9.1
225
1428
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
9.1
1444
12610
L05
ICPC
Flank/axilla symptom/complaint
1.8
9.1
148
831
J99.1*M31.3
ICD-10 Finland
Respiratory disorders in Wegener's granulomatosis
15.6
9.0
14
9
G04BD04
ATC
oxybutynin; oral, transdermal
1.7
9.0
176
1045
H01.9
ICD-10 Finland
Inflammation of eyelid, unspecified
3.9
9.0
35
90
G04CB01
ATC
finasteride; oral (testosterone-5-alpha reductase inhibitors)
1.7
9.0
201
1242
S01GX04
ATC
nedocromil; ophthalmic
2.9
9.0
52
180
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.4
8.9
448
3318
M01AX01
ATC
nabumetone; oral
1.9
8.9
137
754
A07AA02
ATC
nystatin; oral
1.7
8.9
190
1161
ZXC10
NOMESCO Finland
Use of laser
2.5
8.8
65
261
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
8.8
572
4426
L43.9
ICD-10 Finland
Lichen planus, unspecified
2.6
8.8
61
237
-
ICD-10 Finland
NA
2.3
8.8
76
330
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
8.8
721
5781
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.5
8.7
266
1779
S01EC04
ATC
brinzolamide; ophthalmic
1.9
8.7
114
596
R05FB02
ATC
cough suppressants and expectorants
1.3
8.6
1078
9130
DHB50
NOMESCO Finland
Turbinoplasty
2.5
8.6
66
269
H03AA01
ATC
levothyroxine sodium; systemic
1.3
8.6
703
5631
R03BA02
ATC
budesonide; inhalant
1.4
8.6
477
3597
SPAT1260
SPAT
Consultation of another employee
1.4
8.6
501
3808
R13
ICD-10 Finland
Dysphagia
1.7
8.6
167
993
M02AA10
ATC
ketoprofen; topical
1.4
8.6
448
3341
Z00.0
ICD-10 Finland
General medical examination
1.4
8.5
499
3794
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
2.0
8.5
108
554
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.4
8.5
388
2825
CHD00
NOMESCO Finland
Laser trabeculoplasty
3.0
8.5
46
154
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.3
8.4
604
4740
J30.0
ICD-10 Finland
Vasomotor rhinitis
2.3
8.4
72
313
CJB10
NOMESCO Finland
Laser discission of secondary cataract
1.6
8.4
233
1522
CCC50
NOMESCO Finland
Dacryocystectomy
90.3
8.4
9
*
F01
ICPC
Eye pain
2.3
8.4
72
314
D02AE01
ATC
carbamide; topical
1.7
8.4
182
1118
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
12.8
8.4
14
11
CBN00
NOMESCO Finland
Eversion suture of eyelid
+∞
8.3
8
*
CBN40
NOMESCO Finland
Excision of tarsus
+∞
8.3
8
*
R03BA05
ATC
fluticasone; inhalant
1.4
8.3
494
3765
XQ800
NOMESCO Finland
Prick test
1.6
8.2
187
1164
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.2
8.2
1481
13070
R21
ICPC
Throat symptom/complaint
1.4
8.2
474
3598
AA1AD
NOMESCO Finland
CT of head and brain
1.3
8.1
632
5024
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
2.5
8.1
60
243
H04.19
ICD-10 Finland
Other disorders of lacrimal gland
33.4
8.1
10
*
R35
ICD-10 Finland
Polyuria
1.7
8.0
150
882
N81.6
ICD-10 Finland
Rectocele
1.6
8.0
198
1258
R05
ICPC
Cough
1.3
8.0
602
4755
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.3
8.0
532
4127
R01AX03
ATC
ipratropium bromide; nasal
2.3
8.0
68
294
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.9
8.0
114
614
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.2
8.0
1140
9790
R01AD11
ATC
triamcinolone; nasal
1.5
8.0
231
1529
XCK10
NOMESCO Finland
Photography of fundus of eye
1.5
8.0
253
1708
H93.1
ICD-10 Finland
Tinnitus
1.7
7.9
168
1026
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
1.7
7.9
171
1048
R06.0
ICD-10 Finland
Dyspnoea
1.3
7.9
683
5504
UKC02
NOMESCO Finland
Cystoscopy
1.4
7.9
384
2828
R74
ICPC
Upper respiratory infection acute
1.3
7.9
695
5619
K03.80
ICD-10 Finland
Irradiated enamel
1.9
7.8
111
596
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.4
7.8
360
2622
R53
ICD-10 Finland
Malaise and fatigue
1.3
7.8
563
4425
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
7.8
1291
11266
S21
ICPC
Skin texture symptom/complaint
1.4
7.7
317
2263
H10.2
ICD-10 Finland
Other acute conjunctivitis
3.0
7.7
41
137
XKD00
NOMESCO Finland
Uroflowmetry
1.4
7.6
313
2233
Z01.2
ICD-10 Finland
Dental examination
1.2
7.6
1098
9428
J33.0
ICD-10 Finland
Polyp of nasal cavity
2.3
7.6
69
310
S01EX03
ATC
NA
2.3
7.6
69
310
C05AA08
ATC
fluocortolone; rectal, topical
1.4
7.6
373
2752
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.7
7.6
156
945
R09
ICPC
Sinus symptom/complaint
1.6
7.6
187
1190
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
2.1
7.6
84
413
DM1DG
NOMESCO Finland
Paranasal sinuses and face area very extensive MRI examination with high intensity magnet
11.9
7.6
13
11
CCD20
NOMESCO Finland
Suture of lacrimal canaliculus with insertion of tube
25.0
7.6
10
*
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
25.0
7.6
10
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.7
7.6
164
1007
H40.0
ICD-10 Finland
Glaucoma suspect
1.6
7.5
205
1336
JHB00
NOMESCO Finland
Hemorrhoidectomy
2.0
7.5
90
455
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.5
7.5
226
1508
X59
ICD-10 Finland
Exposure to unspecified factor
1.4
7.5
461
3532
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.7
7.5
146
870
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.7
7.4
141
834
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.4
7.4
351
2571
G04CA01
ATC
alfuzosin; oral
1.6
7.4
204
1332
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.5
7.4
263
1821
TCB10
NOMESCO Finland
Simple epilation of cilia
80.2
7.4
8
*
R04.0
ICD-10 Finland
Epistaxis
1.6
7.4
182
1160
H53.1
ICD-10 Finland
Subjective visual disturbances
1.7
7.4
154
938
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
7.4
737
6052
SPAT1053
SPAT
Memory test
1.4
7.4
425
3221
CCB99
NOMESCO Finland
Other operation on lacrimal gland
+∞
7.3
7
*
CBG20
NOMESCO Finland
Plastic repair of margin of eyelid for trichiasis
+∞
7.3
7
*
S01AA12
ATC
tobramycin; ophthalmic
6.8
7.3
17
25
M48.0
ICD-10 Finland
Spinal stenosis
1.4
7.2
324
2348
A02BC04
ATC
rabeprazole; oral
1.5
7.2
218
1461
XG410
NOMESCO Finland
Flow-volume spirometry
1.9
7.2
104
566
J34.3
ICD-10 Finland
Hypertrophy of nasal turbinates
2.6
7.2
48
185
S01EE05
ATC
tafluprost; ophthalmic
1.9
7.2
94
494
H25.0
ICD-10 Finland
Senile incipient cataract
1.6
7.1
158
976
WX720
NOMESCO Finland
Own respiration
1.9
7.1
97
516
N06AA09
ATC
amitriptyline; systemic
1.5
7.1
274
1930
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.7
7.1
154
947
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.0
7.0
86
438
K60.2
ICD-10 Finland
Anal fissure, unspecified
2.8
7.0
42
151
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.4
7.0
333
2441
H25.8
ICD-10 Finland
Other senile cataract
1.4
7.0
303
2184
CBB30
NOMESCO Finland
Excision of lesion of eyelid
2.1
7.0
72
343
S01ED02
ATC
betaxolol; ophthalmic
2.9
7.0
40
138
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.5
6.9
215
1445
H65.3
ICD-10 Finland
Chronic mucoid otitis media
2.4
6.9
55
230
L04AX01
ATC
azathioprine; systemic
1.8
6.9
109
608
S01EE04
ATC
travoprost; ophthalmic
2.2
6.9
66
302
M79.7
ICD-10 Finland
Fibromyalgia
2.0
6.9
87
449
D06BB10
ATC
imiquimod; topical
1.8
6.9
120
693
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
6.9
1202
10508
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.5
6.9
236
1623
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.3
6.9
444
3426
WX400
NOMESCO Finland
Inhalation anesthesy
1.8
6.8
114
648
S22
ICPC
Nail symptom/complaint
1.7
6.8
147
902
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
3.1
6.8
34
109
N40
ICD-10 Finland
Hyperplasia of prostate
1.4
6.8
358
2672
SDA02
NOMESCO Finland
Parodonthologic therapy
1.3
6.8
846
7125
S01AA02
ATC
chlortetracycline; ophthalmic
4.2
6.8
24
58
K59.0
ICD-10 Finland
Constipation
1.7
6.8
148
911
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.6
6.8
153
952
L09
ICPC
Arm symptom/complaint
1.8
6.8
108
607
M01AH01
ATC
celecoxib; oral (coxibs)
1.3
6.8
497
3910
S01EE01
ATC
latanoprost; ophthalmic
1.6
6.8
169
1082
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.4
6.8
293
2111
L71.8
ICD-10 Finland
Other rosacea
2.8
6.7
41
150
XCH00
NOMESCO Finland
Eye pressure measurement
1.8
6.7
102
564
G47.3
ICD-10 Finland
Sleep apnoea
1.3
6.7
464
3617
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.4
6.7
265
1876
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.5
6.7
241
1674
S01GX06
ATC
emedastine; ophthalmic
2.8
6.7
39
138
R06.5
ICD-10 Finland
Mouth breathing
1.6
6.6
186
1222
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.3
6.6
459
3582
R06AX13
ATC
loratadine; oral
1.4
6.6
373
2819
DHB10
NOMESCO Finland
Excision of lesion of internal nose
5.5
6.6
18
33
G04CA02
ATC
tamsulosin; oral
1.3
6.6
402
3075
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.3
6.6
448
3488
J01DA06
ATC
[U] cefuroxime; systemic
1.4
6.5
373
2822
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
1.5
6.5
188
1245
F99
ICPC
Eye/adnexa disease other
4.3
6.5
22
51
WZA90
NOMESCO Finland
Other doctors statement
1.3
6.5
589
4767
U13
ICPC
Bladder symptom/complaint other
1.9
6.5
84
438
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.3
6.5
572
4612
F51.0
ICD-10 Finland
Nonorganic insomnia
1.4
6.5
303
2214
SPAT1211
SPAT
Application of soft bandage
1.5
6.5
247
1738
S01AD03
ATC
aciclovir; ophthalmic
1.9
6.5
86
454
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
3.5
6.5
28
81
C07AA05
ATC
propranolol; systemic
1.3
6.5
499
3951
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.4
6.4
334
2488
H03.1*B00.5
ICD-10 Finland
Herpesviral dermatitis of eyelid
70.0
6.4
7
*
CBG10
NOMESCO Finland
Cryotherapy for trichiasis
70.0
6.4
7
*
S01EC03
ATC
dorzolamide; ophthalmic
2.4
6.4
49
203
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.5
6.4
222
1534
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
2.0
6.4
75
379
A02BC01
ATC
omeprazole; systemic
1.3
6.4
758
6344
L82
ICD-10 Finland
Seborrhoeic keratosis
1.3
6.3
412
3181
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.7
6.3
132
803
SPAT1097
SPAT
Recording of ECG
1.3
6.3
398
3058
R03AK08
ATC
formoterol and beclometasone; inhalant
1.8
6.3
95
525
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
6.3
544
4374
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
1.9
6.3
83
439
N02AC04
ATC
dextropropoxyphene; oral
1.8
6.3
100
563
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
1.7
6.3
120
716
S29
ICPC
Skin symptom/complaint other
1.3
6.3
428
3329
CBE99
NOMESCO Finland
Other operation for entropion
+∞
6.2
6
*
3743B
ICD-9 Finland
Other disorders of eyelids, Ptosis of eyelid[BLEPHAROCHALASIS ET DERMATOCHALASIS]
+∞
6.2
6
*
CBJ99
NOMESCO Finland
Other operation for ptosis
+∞
6.2
6
*
CBN50
NOMESCO Finland
Excision of tarsus and skin
26.7
6.2
8
*
CBD99
NOMESCO Finland
Other plastic reconstruction of eyelid
26.7
6.2
8
*
L03.0
ICD-10 Finland
Cellulitis of finger and toe
1.6
6.2
166
1080
M20.1
ICD-10 Finland
Hallux valgus (acquired)
1.4
6.2
239
1688
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.3
6.2
720
6008
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
1.6
6.2
145
913
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
2.0
6.1
69
344
S01BC03
ATC
diclofenac; ophthalmic
2.1
6.1
63
301
H29
ICPC
Ear symptom/complaint other
1.4
6.1
254
1821
N17
ICPC
Vertigo/dizziness
1.4
6.1
301
2228
M01AG02
ATC
tolfenamic acid; oral, rectal
1.3
6.0
407
3161
H02AB07
ATC
prednisone; oral
1.3
6.0
364
2778
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.4
6.0
231
1628
J01MA12
ATC
levofloxacin; systemic
1.3
6.0
457
3610

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
629
3416
2.01
50.24
2.0
1.7
—
—
—
0
0
2678
22999
1.57
32.98
4.9
4.0
12.6
13.2
mm/h
1.52
2485
21114
2789
24252
1.58
31.78
4.7
4.1
14.9
14.9
pmol/l
0.04
2539
21904
3165
28529
1.69
29.62
5.7
4.9
2.0
2.1
mu/l
0.96
2923
25972
3338
30676
1.79
27.32
16.0
14.4
20.8
24.0
mg/l
6.42
2666
24269
3463
32427
1.86
23.20
11.5
10.3
24.4
24.6
u/l
0.23
3332
31144
3398
31655
1.76
22.96
18.3
16.7
139.6
139.6
mmol/l
0.23
3326
30798
3402
31729
1.76
22.54
18.5
16.8
4.0
4.0
mmol/l
0.38
3320
30815
1247
9681
1.43
22.02
2.6
2.5
61.0
57.1
u/l
0.75
1139
8858
1554
12593
1.40
21.27
2.3
2.1
—
—
—
0
0
2687
23898
1.44
21.21
7.9
7.3
76.3
79.8
u/l
4.33
2527
22318
2455
21494
1.41
21.13
5.1
4.5
—
—
—
0
0
1809
15073
1.39
20.79
4.2
3.8
0.0
0.0
estimate
0.50
327
2787
2117
18104
1.39
20.76
4.4
4.6
6.6
6.7
mmol/l
2.70
1983
16859
2395
20959
1.39
20.11
5.3
4.7
1026.3
2791.6
e6/l
1.68
35
290
1829
15318
1.38
20.11
4.3
3.9
0.0
0.0
estimate
0.13
324
2776
3560
33896
1.95
18.78
24.0
21.2
6.6
6.7
e9/l
2.16
3474
32820
3558
33874
1.94
18.72
24.0
21.2
247.8
254.1
e9/l
7.76
3482
32906
3558
33883
1.93
18.57
23.9
21.1
91.3
91.1
fl
2.27
3515
33313
1797
15125
1.36
18.57
5.5
5.2
0.0
0.0
estimate
0.80
326
2800
2066
17770
1.36
18.56
8.4
8.8
3.9
4.1
e9/l
2.22
1804
15410
3558
33886
1.93
18.52
23.9
21.1
30.4
30.2
pg
5.99
3515
33312
3558
33889
1.93
18.47
24.0
21.2
4.4
4.4
e12/l
1.87
3471
32815
3558
33900
1.92
18.28
24.1
21.3
133.0
133.0
g/l
0.01
3515
33343
828
6143
1.45
18.07
1.8
1.8
1182.9
1183.4
nmol/l
0.01
636
4599
1850
15713
1.35
17.67
6.2
5.7
0.2
0.2
e9/l
0.30
1628
13692
601
4205
1.51
17.60
1.3
1.2
—
—
—
0
0
1836
15584
1.35
17.57
6.1
5.6
1.9
1.9
e9/l
0.01
1628
13621
686
4936
1.48
17.50
1.3
1.2
11.0
11.4
u/ml
0.06
256
1854
1574
13063
1.35
17.43
2.1
2.0
100.7
95.8
pmol/l
3.07
767
6511
1792
15199
1.34
17.03
6.1
5.5
0.0
0.0
e9/l
0.15
1573
13008
1597
13341
1.34
16.69
2.5
2.3
80.7
78.4
nmol/l
2.53
1429
11845
3370
31753
1.59
16.48
15.4
13.6
—
—
—
0
0
1423
11710
1.35
16.35
4.0
3.6
—
5.7
—
0
7
1281
10376
1.36
16.33
6.1
5.6
—
—
—
0
0
1779
15131
1.33
16.32
6.1
5.5
0.6
0.6
e9/l
1.15
1562
12941
1430
11782
1.34
16.27
3.9
3.7
80.9
47.9
ng/l
0.31
989
8199
705
5179
1.44
16.00
1.3
1.3
26.6
33.1
iu/ml
0.91
232
1622
877
6701
1.40
15.96
4.6
4.3
1.0
1.0
kg/l
0.50
136
1038
497
3410
1.53
15.85
1.5
1.4
—
—
—
0
0
3173
29586
1.46
15.59
5.1
4.6
5.8
5.9
mmol/l
3.86
2882
26720
1870
16083
1.32
15.59
6.7
6.5
1.2
1.2
mmol/l
1.89
1595
13510
1705
14478
1.33
15.54
5.4
5.8
1.2
1.2
mmol/l
2.64
1530
13038
1617
13682
1.32
14.89
4.8
4.6
35.6
35.2
g/l
1.82
1494
12644
876
6761
1.39
14.87
1.4
1.3
1.7
1.8
u/ml
0.09
246
1748
505
3526
1.50
14.77
2.3
2.1
123.5
129.9
ug/g
0.15
380
2737
3231
30323
1.47
14.46
5.4
4.9
2.7
2.8
mmol/l
0.76
2969
27620
3011
27905
1.40
14.46
6.2
5.8
39.4
39.9
mmol/mol
2.72
2786
25582
1869
16176
1.31
14.43
5.9
6.0
11.3
11.3
umol/l
0.02
1761
15283
1022
8118
1.36
14.40
4.6
4.2
0.0
0.0
estimate
1.08
325
2755
3169
29681
1.43
13.89
4.9
4.4
4.7
4.7
mmol/l
1.52
2928
27216
544
3916
1.46
13.57
1.5
1.3
455.3
534.6
titre
0.53
115
839
1565
13322
1.30
13.27
2.9
2.8
106.5
120.4
ug/l
2.59
1435
12239
3139
29445
1.40
12.79
4.8
4.3
1.5
1.5
mmol/l
0.33
2883
26816
1145
9380
1.32
12.77
2.2
2.1
163.6
210.8
u/l
1.69
1060
8762
278
1770
1.62
12.22
1.4
1.3
167.6
188.6
u/ml
0.26
258
1617
1644
14272
1.27
11.32
6.4
5.7
2.8
2.8
%
0.05
1521
13234
1667
14498
1.27
11.30
4.1
4.0
—
—
—
0
0
741
5792
1.35
11.21
1.6
1.4
2.4
2.4
g/l
0.19
468
3392
1652
14364
1.27
11.18
6.8
6.0
8.7
8.6
%
0.27
1539
13374
322
2172
1.53
11.01
3.4
2.6
9.7
10.6
g/l
3.76
296
1970
1664
14503
1.26
10.96
6.3
5.6
56.7
57.4
%
1.36
1543
13492
1684
14738
1.26
10.57
6.6
5.8
28.5
27.8
%
1.61
1554
13664
253
1634
1.59
10.49
1.2
1.3
—
—
—
0
0
555
4192
1.38
10.38
2.1
2.0
—
—
—
0
0
365
2559
1.47
10.34
3.7
3.5
—
—
—
0
0
1593
13877
1.26
10.33
6.5
5.8
0.7
0.7
%
0.49
1470
12879
313
2128
1.51
10.31
1.5
1.4
—
—
—
0
0
200
1225
1.67
10.27
3.3
1.5
11.8
15.2
u/ml
0.20
20
27
1092
9114
1.28
10.08
3.0
3.0
1520.2
1538.5
ng/l
0.04
928
7780
859
6951
1.31
10.07
1.7
1.7
12553938.8
31374020.1
pmol/l
0.72
701
5715
3015
28365
1.32
10.00
4.4
3.9
1.3
1.3
mmol/l
0.35
2754
25612
2120
19202
1.24
9.25
3.3
3.1
48.2
47.3
u/l
0.14
1962
17693
928
7669
1.28
9.12
2.7
2.6
4452.0
5814.1
umol/l
0.47
778
6572
798
6469
1.30
9.11
4.8
4.3
—
—
—
0
0
1085
9140
1.26
9.09
4.4
3.9
—
—
—
0
0
62
271
2.31
8.64
1.4
1.3
—
—
—
0
0
969
8099
1.26
8.59
2.4
2.3
2.8
3.0
mg/l
2.55
839
6903
1277
11016
1.24
8.57
2.9
3.3
2.4
2.4
mmol/l
0.37
1078
9511
2336
21471
1.23
8.51
4.3
3.8
—
—
—
0
0
438
3287
1.38
8.46
4.5
4.3
—
—
—
0
0
178
1116
1.62
8.39
1.3
1.2
0.2
1.4
u/ml
2.40
20
98
869
7197
1.27
8.28
4.1
3.8
—
—
—
0
0
900
7491
1.26
8.21
1.6
1.5
21.2
20.8
nmol/l
0.26
749
6344
963
8091
1.26
8.09
3.9
3.5
—
—
—
0
0
126
729
1.75
8.03
2.3
2.0
11.2
11.9
mg/l
0.40
115
673
60
269
2.25
7.92
1.3
1.3
7.0
7.1
g/l
0.05
42
188
70
338
2.09
7.69
1.5
1.2
—
—
—
0
0
59
269
2.21
7.50
1.3
1.3
0.4
0.4
g/l
0.53
42
191
59
269
2.21
7.50
1.3
1.3
2.9
2.8
g/l
0.21
42
189
376
2807
1.38
7.49
2.3
2.2
376.9
379.0
nmol/l
0.07
343
2566
289
2068
1.43
7.36
1.2
1.2
—
—
—
0
0
1412
12465
1.21
7.25
9.8
9.4
1.2
1.3
inr
0.35
398
3532
1098
9493
1.22
6.88
3.8
3.9
7.4
7.4
ph
0.14
202
1798
1141
9908
1.22
6.84
2.3
2.4
—
—
—
0
0
81
434
1.89
6.69
1.5
1.6
0.6
0.8
g/l
0.78
65
328
732
6077
1.25
6.67
5.5
5.1
3.3
3.1
ug/l
0.06
652
5381
1208
10573
1.21
6.64
3.5
3.3
—
—
—
0
0
350
2653
1.35
6.34
2.4
2.3
5.4
6.6
ug/l
0.61
296
2292
195
1337
1.48
6.25
4.7
5.7
1.6
1.6
%
0.34
181
1244
1235
10888
1.20
6.19
3.9
3.6
59.9
119.0
e6/l
3.66
894
7615
214
1514
1.44
5.85
3.0
2.6
0.3
0.3
e6/l
0.17
214
1471
138
897
1.56
5.70
1.1
1.1
—
—
—
0
0
318
2424
1.34
5.56
1.2
1.2
—
—
—
0
0
137
897
1.55
5.49
1.5
1.4
294.2
278.7
ug/g
0.44
78
523
286
2151
1.36
5.47
3.2
3.2
—
—
—
0
0
190
1336
1.44
5.39
1.3
1.2
—
—
—
0
0
188
1332
1.43
5.13
4.8
5.7
0.9
0.9
%
0.28
174
1242
116
745
1.57
5.09
1.4
1.3
3.0
8.7
u/ml
1.84
13
134
114
731
1.58
5.04
1.4
1.2
2.1
2.4
u/ml
—
7
76
410
3299
1.27
4.83
1.3
1.3
—
—
—
0
0
207
1511
1.39
4.79
3.7
3.1
25.6
25.4
mmol/l
0.46
201
1462
581
4868
1.23
4.78
2.4
2.4
13.0
12.6
umol/l
0.62
526
4477
256
1940
1.34
4.69
3.2
3.1
4.4
4.5
pmol/l
0.72
232
1712
146
1004
1.47
4.69
5.3
7.0
1.3
1.3
mmol/l
0.26
129
875
2880
27597
1.19
4.63
16.6
15.6
39.2
39.0
%
0.29
1891
19101
753
6491
1.20
4.63
2.8
2.5
4.8
6.6
e6/l
4.45
668
5658
231
1728
1.36
4.61
2.5
2.4
—
—
—
0
0
125
837
1.51
4.58
1.2
1.1
1.6
7.1
u/ml
2.09
13
90
865
7556
1.19
4.58
2.2
2.3
—
—
—
0
0
772
6678
1.20
4.56
1.6
1.8
1.2
1.3
mg/l
0.52
577
5085
230
1725
1.36
4.52
2.0
1.7
1.5
1.4
g/l
0.12
210
1554
76
460
1.67
4.29
2.5
1.4
—
—
—
0
0
496
4135
1.23
4.27
25.9
25.9
1.3
1.4
inr
0.43
80
585
153
1085
1.43
4.22
1.7
1.6
—
—
—
0
0
531
4480
1.22
4.07
2.3
2.4
2.4
2.3
g/l
0.92
484
4114
1036
9265
1.16
4.05
3.4
3.2
28.7
75.2
e6/l
3.83
814
7071
22
86
2.57
4.04
1.1
1.3
—
—
—
0
0
257
1995
1.31
4.02
2.5
2.4
51.1
22.9
au/ml
—
9
109
607
5193
1.20
4.02
2.8
2.7
1.1
1.3
e6/l
0.87
368
2940
699
6074
1.19
3.88
3.0
2.7
527.2
535.7
mosm/kgh2o
0.48
589
5148
1472
13537
1.14
3.85
10.0
9.4
0.0
0.0
e9/l
1.30
1251
10962
493
4154
1.21
3.83
2.5
2.5
22.2
22.1
%
0.10
395
3492
695
6059
1.18
3.71
2.8
3.0
2.4
2.5
mmol/l
2.29
604
5310
262
2075
1.28
3.55
1.2
1.2
105.0
150.8
iu/ml
1.38
96
773
1072
9701
1.15
3.48
3.4
3.2
34.6
33.9
u/l
0.12
1005
9170
248
1959
1.28
3.44
6.1
6.9
25.0
24.8
mmol/l
0.43
231
1819
281
2261
1.26
3.36
3.8
4.2
0.0
0.5
%
1.28
79
564
361
2991
1.23
3.33
1.6
1.5
—
—
—
0
0
948
8532
1.15
3.31
3.3
3.1
0.3
0.5
e6/l
6.61
726
6432
51
300
1.71
3.28
1.6
2.3
5.5
9.2
umol/l
1.00
34
220
255
2036
1.27
3.26
4.4
5.0
—
—
—
0
0
94
642
1.48
3.24
1.6
1.5
13.1
12.1
u/l
0.22
83
508
173
1319
1.33
3.14
2.6
2.2
12.3
11.8
nmol/l
0.26
146
1160
140
1035
1.37
3.12
2.5
2.5
—
—
—
0
0
58
359
1.63
3.10
1.0
1.1
1.5
1.5
g/l
0.08
53
328
148
1110
1.35
3.02
2.8
3.1
0.3
0.3
g/l
0.15
49
437
73
482
1.52
2.98
1.4
1.3
—
—
—
0
0
45
264
1.71
2.95
1.2
1.0
—
—
—
0
0
226
1803
1.27
2.94
1.4
1.3
41.3
51.9
au/ml
—
7
80
73
484
1.52
2.93
2.9
3.8
1.5
1.4
%
0.02
53
376
282
2310
1.24
2.92
3.7
3.9
0.9
0.6
%
0.68
71
509
103
732
1.42
2.91
6.1
8.1
11.2
11.0
mmol/l
0.38
90
650
103
733
1.42
2.89
6.1
8.1
104.7
105.0
mmol/l
0.22
90
651
293
2413
1.23
2.89
4.0
4.1
0.1
0.1
%
0.01
92
665
59
374
1.59
2.89
1.5
1.4
22.1
29.9
u/l
1.15
48
311
122
898
1.37
2.82
1.3
1.2
—
—
—
0
0
31
165
1.89
2.80
2.1
2.4
0.1
0.2
e9/l
0.46
31
160
8
18
4.45
2.79
1.0
1.0
—
—
—
0
0
14
53
2.65
2.79
1.4
1.3
86.4
88.0
ng/l
0.03
14
53
305
2533
1.22
2.78
4.0
4.1
0.8
0.9
%
0.27
95
720
78
531
1.48
2.78
1.5
1.5
—
—
—
0
0
46
278
1.66
2.73
1.1
1.0
0.2
0.6
u/ml
0.73
12
78
56
356
1.58
2.73
1.5
1.5
48.6
59.7
%
1.20
34
231
2621
25272
1.12
2.70
18.8
17.5
13.7
13.7
%
1.25
2567
24674
36
204
1.77
2.69
6.6
6.3
—
—
—
0
0
328
2758
1.21
2.65
3.6
3.0
224.2
213.5
ng/l
0.15
303
2513
265
2184
1.23
2.62
2.3
2.3
—
—
—
0
0
368
3135
1.19
2.59
1.6
1.6
—
—
—
0
0
61
401
1.53
2.58
1.1
1.1
3.2
2.6
u/ml
0.15
16
98
565
4985
1.16
2.58
2.8
3.3
0.8
0.8
mmol/l
1.02
527
4620
45
275
1.64
2.58
2.0
1.6
—
—
—
0
0
113
835
1.36
2.58
1.3
1.2
—
—
—
0
0
977
8942
1.13
2.56
3.4
3.2
675.2
358.8
mg/l
0.84
574
5458
103
751
1.38
2.56
1.3
1.3
193.3
215.6
miu/ml
0.27
43
346
53
341
1.56
2.48
1.5
1.4
276.8
277.6
mosm/kgh2o
0.10
41
254
352
3004
1.19
2.44
2.2
2.2
0.2
0.2
g/l
0.11
316
2796
1025
9434
1.12
2.43
4.1
3.9
6.6
8.5
mg/mmol
1.00
622
5758
906
8282
1.12
2.41
3.2
3.1
—
—
—
0
0
16
70
2.29
2.41
1.1
1.3
—
—
—
0
0
47
297
1.59
2.38
5.0
4.7
50.3
78.8
u/ml
0.44
18
90
60
401
1.50
2.38
2.4
2.9
—
—
—
0
0
409
3546
1.17
2.36
2.5
2.5
1.7
1.8
%
0.90
361
3134
154
1211
1.28
2.31
1.4
1.4
33.8
30.6
iu/l
0.52
141
1033
47
301
1.57
2.27
1.1
1.1
5.2
3.8
u/ml
0.22
21
125
1031
9525
1.11
2.26
3.2
3.1
6.6
7.1
mmol/l
3.57
882
7950
311
2645
1.19
2.26
2.5
2.5
67.1
66.3
g/l
1.28
283
2379
127
977
1.31
2.26
13.5
10.4
—
—
—
0
0
342
2934
1.18
2.25
3.7
3.8
2.1
2.0
mmol/l
0.28
282
2391
912
8374
1.12
2.24
4.0
4.2
—
—
—
0
0
178
1433
1.25
2.22
1.9
1.9
—
—
—
0
0
16
73
2.20
2.20
1.6
2.0
—
—
—
0
0
42
265
1.59
2.17
2.0
2.2
1.0
1.1
e9/l
0.21
23
164
670
6057
1.13
2.14
4.4
3.8
198.1
319.5
ng/l
1.75
519
4768
433
3801
1.16
2.14
1.6
1.6
—
—
—
0
0
877
8055
1.12
2.13
1.7
1.6
1.3
1.4
mmol/l
1.18
736
6719
104
785
1.33
2.13
1.3
1.2
65.0
92.1
titre
—
8
58
234
1950
1.21
2.12
3.6
3.8
7.4
7.4
ph
0.07
30
242
92
682
1.36
2.12
2.3
2.2
126.5
127.4
g/l
0.13
76
505
458
4042
1.15
2.11
5.5
5.4
1.0
1.0
mmol/l
0.23
426
3720
46
299
1.55
2.11
3.1
3.7
58.5
57.0
%
0.14
26
195
334
2880
1.18
2.08
5.8
7.9
120.1
119.7
g/l
0.13
316
2767
100
754
1.34
2.07
2.6
3.1
—
—
—
0
0
310
2659
1.18
2.06
2.5
2.5
67.4
69.7
e9/l
0.62
245
2005
299
2558
1.18
2.05
3.8
3.7
91.4
88.6
ng/l
0.19
258
2152
235
1971
1.21
2.01
3.7
3.8
5.1
5.2
kpa
2.47
208
1831
288
2463
1.18
1.99
3.2
3.2
4.4
4.6
kpa
0.55
281
2384
54
369
1.47
1.98
2.3
2.6
—
—
—
0
0
97
734
1.33
1.97
1.6
1.6
17304.5
13568.5
e6/l
0.22
73
535
399
3506
1.15
1.96
5.4
7.1
1.7
1.2
mmol/l
1.56
296
2723
24
134
1.80
1.95
2.1
2.5
864.9
1154.4
u/ml
0.38
24
134
9
33
2.73
1.93
1.0
1.2
1.7
1.7
umol/24h
—
9
33
355
3099
1.16
1.91
5.6
7.5
95.2
95.6
%
0.37
336
2978
18
92
1.96
1.89
1.2
1.4
0.7
3.5
%
1.83
13
74
538
4836
1.13
1.89
3.0
2.9
2.6
3.2
e6/l
0.99
303
2596
249
2113
1.19
1.89
2.5
2.9
3.9
4.1
e9/l
0.59
184
1625
339
2954
1.16
1.87
3.7
3.8
5.9
5.8
kpa
0.92
333
2865
31
189
1.65
1.87
1.2
1.0
—
—
—
0
0
2635
25607
1.10
1.86
21.2
18.7
332.0
331.4
g/l
3.21
2624
25383
49
337
1.46
1.77
1.1
1.1
10.7
2.9
u/ml
0.77
19
129
33
208
1.59
1.76
1.1
1.0
—
—
—
0
0
61
438
1.40
1.75
1.1
1.3
—
—
—
0
0
49
338
1.46
1.75
2.7
1.9
211.8
196.5
pmol/l
0.45
49
320
310
2702
1.16
1.72
3.5
3.5
1.2
1.2
mmol/l
0.35
266
2336
70
516
1.36
1.72
1.2
1.2
280.4
256.6
u/ml
0.27
33
291
29
178
1.63
1.72
2.0
1.6
—
—
—
0
0
307
2677
1.16
1.70
1.6
1.4
—
—
—
0
0
79
595
1.33
1.70
1.5
1.4
56.4
61.5
mmol/l
0.56
66
479
31
195
1.59
1.68
1.2
1.3
0.1
1.1
u/ml
1.23
14
95
42
284
1.48
1.66
1.1
1.1
—
—
—
0
0
65
477
1.37
1.66
1.0
1.1
—
—
—
0
0
66
488
1.36
1.61
1.3
1.4
99.0
112.4
u/ml
0.54
15
86
395
3522
1.14
1.60
5.4
7.1
5.1
5.1
kpa
0.02
372
3342
395
3522
1.14
1.60
5.4
7.1
12.3
12.4
kpa
0.17
370
3340
38
254
1.50
1.60
1.1
1.2
—
—
—
0
0
42
288
1.46
1.57
1.4
1.7
—
—
—
0
0
170
1426
1.20
1.52
3.7
3.9
—
—
—
0
0
513
4667
1.11
1.50
2.0
2.1
29.3
29.8
s
1.05
495
4520
28
178
1.58
1.48
1.1
1.0
—
—
—
0
0
38
261
1.46
1.43
1.7
1.5
29.5
31.8
%
0.14
21
168
66
499
1.33
1.43
1.2
1.1
2.0
1.9
u/ml
0.03
24
217
192
1640
1.18
1.42
7.3
10.1
—
—
—
0
0
443
4012
1.12
1.41
1.3
1.3
—
—
—
0
0
55
407
1.36
1.38
1.2
1.1
2.2
2.6
u/ml
0.20
25
164
242
2113
1.16
1.37
1.7
1.6
—
—
—
0
0
5
17
2.94
1.36
1.6
1.3
—
—
—
0
0
417
3781
1.12
1.32
5.0
6.5
103.9
104.2
mmol/l
0.68
405
3702
94
756
1.25
1.30
3.5
3.1
24.3
25.2
mmol/l
1.70
78
660
87
694
1.26
1.29
3.2
3.5
25.5
25.6
mg/l
0.00
58
437
297
2645
1.13
1.27
4.2
4.0
—
—
—
0
0
193
1667
1.17
1.27
4.1
3.5
—
—
—
0
0
384
3475
1.12
1.26
3.1
3.1
0.8
0.8
ug/l
0.28
264
2339
18
107
1.69
1.25
1.2
1.3
62.2
53.7
pmol/l
—
5
41
14
77
1.82
1.25
1.6
2.0
—
—
—
0
0
57
432
1.32
1.25
1.1
1.1
0.8
1.1
u/ml
0.36
24
198
16
92
1.74
1.25
2.4
2.3
—
—
—
0
0
13
70
1.86
1.23
1.6
1.4
—
—
—
0
0
23
147
1.57
1.22
2.9
2.4
8.0
9.5
mmol/l
1.85
17
119
103
844
1.23
1.22
4.7
4.5
—
—
—
0
0
217
1899
1.15
1.21
1.4
1.4
—
—
—
0
0
147
1248
1.19
1.21
3.7
4.1
24.8
25.0
mmol/l
0.42
131
1155
277
2468
1.13
1.19
1.4
1.4
—
—
—
0
0
25
165
1.52
1.17
1.0
1.0
—
—
—
0
0
315
2833
1.12
1.17
2.6
2.4
34.6
55.5
u/l
0.65
255
2404
37
268
1.38
1.10
2.3
2.4
—
—
—
0
0
16
256
0.62
1.09
1.1
1.3
1.3
1.5
nmol/l
0.34
16
232
50
381
1.32
1.09
1.0
1.1
—
—
—
0
0
68
540
1.26
1.08
1.4
1.4
—
—
—
0
0
68
540
1.26
1.08
2.9
2.8
—
—
—
0
0
7
32
2.19
1.08
1.3
1.1
—
—
—
0
0
50
382
1.31
1.07
1.0
1.1
—
—
—
0
0
18
113
1.60
1.05
2.1
2.0
—
—
—
0
0
6
121
0.50
1.05
1.3
1.4
—
—
—
0
0
57
445
1.29
1.05
1.1
1.1
5.5
5.7
u/ml
0.02
26
240
5
22
2.27
1.03
1.0
1.3
—
1.1
—
0
5
9
46
1.96
1.03
1.0
1.0
—
—
—
0
0
90
743
1.22
1.03
2.9
3.5
8.6
8.4
kpa
0.49
82
693
20
130
1.54
1.02
1.2
1.2
—
—
—
0
0
89
735
1.22
1.02
2.0
1.6
5.4
5.0
iu/l
0.12
34
251
59
465
1.27
1.01
1.1
1.1
—
—
—
0
0
9
48
1.88
1.00
1.2
1.4
—
—
—
0
0
92
765
1.21
0.99
1.4
1.9
—
—
—
0
0
11
61
1.81
0.98
3.8
3.9
—
104.9
—
0
12
46
353
1.31
0.97
1.4
1.2
—
—
—
0
0
88
730
1.21
0.97
1.2
1.2
—
—
—
0
0
25
173
1.45
0.97
1.6
2.3
681.4
655.4
e6/l
0.06
17
76
97
813
1.20
0.97
1.3
1.8
—
—
—
0
0
26
183
1.42
0.93
1.3
1.2
—
—
—
0
0
22
150
1.47
0.92
1.3
1.1
1.5
13.0
nmol/l
—
5
31
43
330
1.31
0.92
2.3
4.2
—
—
—
0
0
36
476
0.75
0.92
1.3
1.3
—
—
—
0
0
160
1404
1.15
0.92
1.4
1.8
1.5
1.5
g/l
0.16
132
1204
93
781
1.20
0.92
3.6
4.2
1.5
1.5
mg/l
0.36
85
713
28
201
1.40
0.91
1.2
1.1
7.3
10.4
iu/ml
—
6
47
23
159
1.45
0.91
1.6
1.6
—
—
—
0
0
34
253
1.35
0.90
1.2
1.2
—
—
—
0
0
140
1220
1.15
0.89
3.6
4.2
—
—
—
0
0
42
323
1.30
0.89
1.3
1.4
—
—
—
0
0
42
323
1.30
0.89
1.3
1.4
—
—
—
0
0
42
323
1.30
0.89
1.3
1.4
—
—
—
0
0
42
323
1.30
0.89
1.3
1.4
—
—
—
0
0
6
29
2.07
0.89
1.0
1.1
—
—
—
0
0
23
160
1.44
0.88
1.2
1.4
—
—
—
0
0
31
228
1.36
0.88
1.2
1.2
104.0
189.1
titre
—
5
44
18
119
1.52
0.88
1.1
1.0
0.1
0.3
u/ml
—
6
19
66
539
1.23
0.87
1.4
1.5
—
—
—
0
0
45
352
1.28
0.85
12.5
4.6
7.8
7.1
mmol/l
0.64
38
297
158
1395
1.14
0.85
2.3
2.8
0.6
0.7
%
0.08
153
1336
12
72
1.67
0.85
1.1
1.1
—
—
—
0
0
118
1021
1.16
0.84
2.5
3.1
40.1
116.0
mg/l
0.79
98
852
97
826
1.18
0.84
1.4
1.9
—
—
—
0
0
14
88
1.59
0.84
1.1
1.3
57.6
31.9
%
—
8
63
29
213
1.36
0.84
1.9
2.0
16.3
13.6
%
0.42
11
95
118
1022
1.16
0.83
2.5
3.1
74.2
59.0
mg/l
0.12
96
853
8
138
0.58
0.83
1.3
1.2
—
—
—
0
0
34
444
0.76
0.82
1.0
1.1
18.0
1489.2
iu/ml
—
9
89
16
237
0.67
0.81
1.9
3.3
10.9
10.8
%
0.02
16
237
12
73
1.65
0.81
1.7
1.9
—
—
—
0
0
12
73
1.65
0.81
1.2
1.0
18.6
5.4
u/ml
—
5
10
25
341
0.73
0.81
1.8
1.4
55632.5
50230.5
e6/l
0.08
16
198
107
923
1.16
0.80
2.9
3.5
—
—
—
0
0
29
216
1.35
0.78
2.0
2.0
70.3
71.5
%
0.16
29
206
106
916
1.16
0.78
3.7
3.6
3.8
3.8
mmol/l
0.02
100
861
96
823
1.17
0.78
1.4
1.8
—
—
—
0
0
45
357
1.26
0.78
1.7
1.6
—
—
—
0
0
14
211
0.66
0.78
1.1
1.1
—
—
—
0
0
20
281
0.71
0.78
1.4
2.2
2.4
1.9
u/field
0.25
11
110
77
649
1.19
0.77
2.7
2.4
16.6
16.0
%
0.66
48
324
15
99
1.52
0.75
1.7
1.6
—
—
—
0
0
21
149
1.41
0.75
12.9
12.3
—
—
—
0
0
64
535
1.20
0.71
1.7
1.5
—
—
—
0
0
99
860
1.16
0.70
1.9
2.1
5596.8
4105.7
u/l
0.18
42
325
1024
9872
1.05
0.70
3.1
2.8
—
—
—
0
0
286
2644
1.09
0.69
4.6
6.7
1.3
1.4
mmol/l
1.04
276
2538
113
993
1.14
0.69
2.5
3.0
1.6
1.5
ratio
0.16
14
86
17
119
1.43
0.66
1.3
1.1
—
—
—
0
0
37
294
1.26
0.66
1.3
1.4
15420.7
123573.4
e6/l
1.62
21
198
43
348
1.24
0.66
2.5
2.8
—
—
—
0
0
94
819
1.15
0.65
1.4
1.9
—
—
—
0
0
81
698
1.16
0.65
2.2
2.3
93.7
109.4
ug/min
0.13
41
414
47
385
1.22
0.65
2.9
2.3
—
—
—
0
0
38
304
1.25
0.65
1.6
1.4
22.6
26.3
iu/ml
—
5
15
137
1227
1.12
0.64
1.7
1.9
1.4
1.9
ug/l
0.32
122
1070
49
405
1.21
0.63
1.9
1.7
—
—
—
0
0
9
138
0.65
0.60
2.1
1.6
—
—
—
0
0
58
490
1.19
0.60
1.5
1.4
—
—
—
0
0
46
380
1.21
0.60
1.4
1.5
—
—
—
0
0
19
139
1.37
0.60
1.1
1.1
0.6
4.6
u/ml
—
7
47
24
311
0.77
0.59
1.7
1.5
—
—
—
0
0
470
4458
1.06
0.59
1.8
1.8
—
—
—
0
0
0
22
0.00
0.59
0.0
2.5
—
37.0
—
0
7
54
639
0.84
0.59
2.3
3.3
—
—
—
0
0
160
1454
1.10
0.59
1.4
1.4
—
—
—
0
0
6
35
1.72
0.57
18.8
13.6
9.9
5.4
mmol/l
—
6
35
21
158
1.33
0.57
1.3
1.2
—
—
—
0
0
10
65
1.54
0.55
1.9
2.4
—
—
—
0
0
43
357
1.21
0.55
1.2
1.4
251.5
286.9
pmol/l
0.46
31
280
24
186
1.29
0.54
1.1
1.0
301.9
343.9
ng/l
0.65
13
121
20
151
1.33
0.53
1.1
1.1
0.6
1.2
u/ml
—
8
62
9
61
1.48
0.53
1.1
1.1
—
—
—
0
0
15
108
1.39
0.53
2.6
2.7
—
—
—
0
0
15
108
1.39
0.53
1.1
1.1
1323.7
1609.5
miu/ml
0.60
15
108
29
232
1.25
0.52
1.4
1.3
—
—
—
0
0
74
648
1.14
0.52
1.5
1.8
—
—
—
0
0
30
242
1.24
0.51
4.8
2.4
—
—
—
0
0
25
314
0.79
0.50
1.1
1.1
—
—
—
0
0
48
407
1.18
0.50
1.2
1.2
—
—
—
0
0
6
41
1.46
0.50
3.0
3.1
—
—
—
0
0
85
754
1.13
0.50
2.1
2.2
—
—
—
0
0
35
288
1.22
0.50
1.3
1.4
6.7
6.4
mmol/l
0.17
30
270
35
288
1.22
0.50
1.1
1.1
358.6
355.1
nmol/l
0.04
26
248
80
903
0.88
0.50
1.4
1.4
—
—
—
0
0
22
171
1.29
0.49
1.3
1.3
—
—
—
0
0
7
45
1.56
0.49
2.3
3.2
—
—
—
0
0
45
381
1.18
0.48
1.8
1.4
38.5
40.3
mu/l
0.05
40
337
810
7842
1.04
0.48
6.7
6.6
—
—
—
0
0
7
47
1.49
0.47
1.7
1.7
—
—
—
0
0
94
844
1.12
0.46
1.6
1.6
284.1
310.5
mu/l
0.55
87
768
25
200
1.25
0.46
1.6
1.4
1589.4
1853.6
ml
—
9
44
284
2687
1.06
0.43
6.6
6.8
9.5
9.9
mmol/l
0.54
265
2549
32
382
0.84
0.42
1.7
1.4
1516.4
2107.1
e6/l
0.44
25
279
25
306
0.82
0.42
1.9
1.5
—
—
—
0
0
58
509
1.14
0.42
2.0
1.8
1.7
1.7
mmol/l
0.05
58
496
0
15
0.00
0.41
0.0
3.4
—
2.6
—
0
6
27
326
0.83
0.41
1.6
1.6
—
—
—
0
0
26
213
1.22
0.40
1.2
1.1
—
—
—
0
0
13
172
0.75
0.40
2.8
3.0
—
—
—
0
0
143
1541
0.93
0.39
3.6
4.3
24.2
24.2
mmol/l
0.06
133
1396
795
7730
1.04
0.39
3.8
3.8
90.9
90.0
%
0.46
774
7518
23
187
1.23
0.39
1.1
1.0
649.4
684.8
ng/l
0.15
12
118
65
580
1.12
0.38
2.5
2.7
—
—
—
0
0
9
67
1.34
0.38
1.0
1.2
—
—
—
0
0
122
1126
1.09
0.38
3.0
3.3
1066.0
1686.3
u/ml
0.21
106
950
26
216
1.21
0.36
2.0
2.5
7.0
6.8
mmol/l
0.13
21
143
6
42
1.43
0.35
1.2
1.2
—
—
—
0
0
6
43
1.40
0.35
1.5
1.0
—
—
—
0
0
82
747
1.10
0.34
1.1
1.1
—
—
—
0
0
6
45
1.33
0.33
3.0
3.0
—
—
—
0
0
55
491
1.12
0.33
1.5
1.2
20.4
32.8
u/l
1.29
48
418
102
1103
0.92
0.32
1.7
2.1
22.2
21.4
s
0.26
89
972
7
54
1.30
0.30
2.7
2.2
12.5
17.6
umol/l
—
7
54
79
725
1.09
0.30
3.5
3.3
1.0
0.8
nmol/l
0.79
59
565
329
3418
0.96
0.30
3.5
3.9
13.1
23.2
ug/l
0.77
271
2743
62
564
1.10
0.28
2.6
1.9
1.0
0.8
nmol/l
0.86
52
468
73
670
1.09
0.28
2.7
3.5
—
—
—
0
0
8
63
1.27
0.27
1.0
1.3
18.3
17.2
umol/l
—
8
57
44
394
1.12
0.27
1.2
1.3
—
—
nmol/l
—
0
0
35
395
0.89
0.26
1.6
1.4
—
—
—
0
0
9
72
1.25
0.25
4.0
5.0
—
—
—
0
0
93
995
0.93
0.25
1.5
2.2
38.3
37.4
g/l
0.85
76
844
68
627
1.09
0.25
1.7
1.4
24.2
21.8
e6/l
0.06
57
476
36
403
0.89
0.24
1.6
1.5
—
—
—
0
0
9
76
1.18
0.24
1.0
1.1
—
—
—
0
0
20
170
1.18
0.24
1.9
2.7
7.4
7.4
ph
—
5
56
35
392
0.89
0.24
1.5
1.4
—
—
—
0
0
11
87
1.27
0.24
1.3
1.5
—
—
—
0
0
9
77
1.17
0.24
1.0
1.0
—
—
—
0
0
24
276
0.87
0.24
2.3
2.2
—
—
—
0
0
68
629
1.08
0.23
1.7
1.5
7263.3
1149.4
e6/l
0.44
62
511
36
401
0.90
0.23
1.2
1.2
—
—
—
0
0
5
38
1.32
0.23
1.0
1.0
—
—
—
0
0
5
38
1.32
0.23
2.4
3.0
—
14.7
—
0
8
125
1184
1.06
0.23
2.3
2.4
10.2
10.4
g/l
0.17
98
996
18
211
0.85
0.23
1.1
1.6
1.1
1.2
promille
0.09
13
168
19
162
1.17
0.22
1.4
1.2
—
—
—
0
0
7
94
0.74
0.22
1.0
2.0
—
—
—
0
0
22
191
1.15
0.21
1.6
1.2
—
—
—
0
0
34
305
1.12
0.21
1.3
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
6.7
—
—
—
0
0
17
145
1.17
0.20
1.3
1.2
110.1
335.0
u/l
1.86
17
132
13
155
0.84
0.20
1.9
2.4
34.6
39.8
%
—
6
60
18
207
0.87
0.19
1.8
1.5
1.1
1.0
g/l
0.68
18
207
25
279
0.90
0.17
1.2
1.2
—
—
—
0
0
72
679
1.06
0.17
1.9
1.5
—
—
—
0
0
205
1985
1.03
0.17
3.1
3.8
29.2
67.3
u/ml
6.50
198
1909
61
572
1.07
0.17
2.6
2.5
—
—
—
0
0
5
66
0.76
0.17
1.6
1.3
—
—
—
0
0
5
69
0.72
0.17
1.0
1.6
15.0
25.7
g/l
—
5
57
8
70
1.14
0.16
1.8
1.1
—
—
—
0
0
9
79
1.14
0.15
1.0
1.0
—
—
—
0
0
9
80
1.13
0.15
1.7
2.0
—
—
—
0
0
31
284
1.09
0.15
1.3
1.1
—
—
—
0
0
17
150
1.13
0.14
6.1
3.6
—
—
—
0
0
801
8108
0.98
0.14
1.4
1.4
—
—
—
0
0
151
1560
0.97
0.14
6.3
8.9
24.7
24.4
mmol/l
0.59
139
1450
10
84
1.19
0.14
1.2
1.1
—
—
—
0
0
137
1325
1.04
0.13
1.6
1.7
—
—
—
0
0
27
249
1.08
0.12
2.3
1.8
—
1.4
—
0
14
26
280
0.93
0.10
1.6
1.6
—
—
—
0
0
16
144
1.11
0.10
1.9
1.3
141.4
134.5
nmol/l
0.34
16
144
12
106
1.13
0.09
2.1
2.0
13.6
11.4
%
0.30
12
97
37
350
1.06
0.09
1.1
1.3
—
—
—
0
0
39
411
0.95
0.09
1.8
1.7
88.9
89.6
%
0.33
39
405
6
58
1.03
0.08
1.3
1.1
—
—
—
0
0
6
58
1.03
0.08
1.3
1.1
—
—
—
0
0
6
58
1.03
0.08
1.3
1.1
—
—
—
0
0
10
113
0.88
0.08
1.0
1.2
—
—
—
0
0
284
2882
0.98
0.08
1.4
1.4
—
—
—
0
0
7
66
1.06
0.08
1.4
1.3
—
—
—
0
0
39
409
0.95
0.08
1.1
1.2
—
—
—
0
0
18
166
1.08
0.07
5.8
3.5
—
—
—
0
0
7
81
0.86
0.07
1.9
1.4
—
—
—
0
0
86
837
1.03
0.07
2.7
3.8
7.4
7.4
ph
1.08
69
692
7
84
0.83
0.07
1.0
1.8
—
—
—
0
0
9
86
1.05
0.07
1.9
1.9
—
—
—
0
0
209
2122
0.98
0.07
1.3
1.3
—
—
—
0
0
8
91
0.88
0.06
2.6
1.8
—
—
—
0
0
39
407
0.96
0.06
4.7
5.1
382.0
363.9
umol/l
0.30
32
352
11
99
1.11
0.06
2.0
1.4
—
—
—
0
0
37
386
0.96
0.06
1.5
1.5
0.4
0.3
nmol/l
0.27
31
299
57
588
0.97
0.06
1.7
1.4
—
—
—
0
0
26
274
0.95
0.06
3.0
2.8
93.4
21.5
mg/l
0.41
18
199
17
158
1.08
0.06
3.2
2.1
—
—
—
0
0
353
3497
1.01
0.05
2.7
2.6
6.5
8.6
umol/l
2.41
314
2998
106
1039
1.02
0.05
2.0
2.2
533.4
689.5
ug/l
0.18
98
975
40
385
1.04
0.05
1.7
2.2
—
—
—
0
0
20
188
1.06
0.05
3.8
3.4
—
—
—
0
0
23
219
1.05
0.04
1.3
1.3
12.9
11.2
u/l
0.23
17
199
40
412
0.97
0.04
1.2
1.2
3.5
5.0
u/ml
0.68
19
169
32
309
1.04
0.03
1.3
1.2
—
—
—
0
0
14
131
1.07
0.03
1.5
2.6
76.4
168.1
umol/l
—
9
73
54
528
1.02
0.03
1.2
1.2
—
—
—
0
0
43
420
1.02
0.02
1.5
1.5
30.8
32.1
g/l
0.27
38
385
17
162
1.05
0.02
1.2
1.3
5.3
5.8
mmol/l
1.75
17
154
27
278
0.97
0.02
1.1
1.1
—
—
—
0
0
259
2578
1.00
0.01
5.9
7.9
—
—
—
0
0
11
104
1.06
0.01
1.7
1.8
30.6
27.0
%
0.47
11
97
11
104
1.06
0.01
2.7
2.7
—
—
—
0
0
12
126
0.95
0.00
1.4
5.1
61.6
61.5
mg/l
—
7
90
14
146
0.96
0.00
3.9
2.3
—
—
—
0
0
26
266
0.98
0.00
1.2
1.6
4.6
4.1
ug/l
0.11
20
222
33
325
1.02
0.00
3.5
3.3
—
—
—
0
0
42
415
1.01
0.00
1.3
1.3
—
—
—
0
0
70
704
0.99
0.00
2.9
3.9
3.0
2.7
mmol/l
0.22
42
485
32
316
1.01
0.00
1.6
1.9
—
—
—
0
0
38
377
1.01
0.00
1.1
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
499.1
—
0
6
5
50
1.00
0.00
2.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
9
91
0.99
0.00
1.3
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
187
1870
1.00
0.00
6.3
8.5
93.0
93.9
%
0.56
187
1861
8
82
0.98
0.00
1.3
1.2
—
—
—
0
0
8
87
0.92
0.00
1.5
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
87
0.92
0.00
1.4
1.2
—
—
—
0
0
9
95
0.95
0.00
1.0
1.2
—
—
—
0
0
9
89
1.01
0.00
2.3
2.6
0.8
1.2
ug/l
—
9
83
0
7
0.00
0.00
0.0
1.1
—
118.1
—
0
7
100
1000
1.00
0.00
1.1
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
164.0
—
0
5
8
88
0.91
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
6
64
0.94
0.00
1.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
3125.7
—
0
7

Mortality – FinRegistry

Association

Association between endpoint H7_STENOLACRI and mortality.

Females

Parameter HR [95% CI] p-value
H7_STENOLACRI 0.837 [0.76, 0.92] < 0.001
Birth year 0.996 [0.99, 1.0] 0.322

During the follow-up period (1.1.1998 — 31.12.2019), 2226 out of 15639 females with H7_STENOLACRI died.

Males

Parameter HR [95% CI] p-value
H7_STENOLACRI 0.921 [0.82, 1.03] 0.155
Birth year 0.99 [0.98, 1.0] 0.03

During the follow-up period (1.1.1998 — 31.12.2019), 1205 out of 7490 males with H7_STENOLACRI died.

Mortality risk

Mortality risk for people of age

years, who have H7_STENOLACRI.

N-year risk Females Males
1 0.082% 0.164%
5 0.508% 1.095%
10 1.342% 2.76%
15 2.472% 5.507%
20 4.285% 9.351%

Relationships between endpoints

Index endpoint: H7_STENOLACRI – Stenosis and insufficiency of lacrimal passages

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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