No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
434 |
4. Check minimum number of eventsNone |
434 |
5. Include endpointsNone |
434 |
6. Filter based on genotype QC (FinnGen only) |
434 |
Control definitions (FinnGen only)
- Control exclude
- M13_DORSOPATHY
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M46
- Name in latin
- Infectio disci intervertebralis (pyogenes)
Similar endpoints
↥List of similar endpoints to
Infection of intervertebral disc (pyogenic)
based on the number of shared cases.
Similar with more cases:
- Autoimmune diseases related-to ILD
- Spondylopathies
- Dorsopathies
- Diseases of the musculoskeletal system and connective tissue
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2789 | 1003 | 1779 |
| Only index persons | 2627 | 945 | 1682 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.03 | 0.05 |
| Only index persons | 0.05 | 0.03 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 64.58 | 68.10 | 62.60 |
| Only index persons | 64.18 | 67.66 | 62.22 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 434 | 135 | 299 |
| Unadjusted period prevalence (%) | 0.11 | 0.05 | 0.13 |
| Median age at first event (years) | 66.68 | 68.96 | 65.64 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 383
- Matched controls
- 3828
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M46.3
ICD-10 Finland
Infection of intervertebral disc (pyogenic)
+∞
323.0
382
*
M46.4
ICD-10 Finland
Discitis, unspecified
+∞
121.5
110
*
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
262.5
114.5
112
6
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
64.2
99.5
114
25
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
30.3
83.1
113
52
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
103.2
82.2
88
11
M54.5
ICD-10 Finland
Low back pain
9.7
82.0
206
408
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
50.0
69.2
83
21
N03AX16
ATC
pregabalin; oral
8.7
62.8
157
282
M48.0
ICD-10 Finland
Spinal stenosis
48.7
62.3
75
19
N02AA05
ATC
oxycodone; systemic
8.2
58.1
150
278
N02AX02
ATC
tramadol; systemic, rectal
5.8
56.1
245
899
A49.9
ICD-10 Finland
Bacterial infection, unspecified
8.1
54.4
139
250
NA3DG
NOMESCO Finland
Lumbar spine very extensive MRI examination with high intensity magnet
583.1
52.8
51
*
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
30.6
46.4
62
24
J04AB02
ATC
rifampicin; systemic
48.8
42.5
51
12
M54.4
ICD-10 Finland
Lumbago with sciatica
10.3
42.1
88
108
N03AX12
ATC
gabapentin; oral
8.7
41.4
96
141
M54.9
ICD-10 Finland
Dorsalgia, unspecified
12.1
41.1
78
79
G06.1
ICD-10 Finland
Intraspinal abscess and granuloma
441.6
40.9
40
*
J01FF01
ATC
clindamycin; systemic
4.7
40.5
184
631
L03
ICPC
Low back symptom/complaint
5.6
39.4
134
333
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
144.2
37.5
39
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.1
36.8
249
1201
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
5.2
36.1
133
357
A41.9
ICD-10 Finland
Sepsis, unspecified
13.0
34.8
63
57
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
8.1
34.1
82
125
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
61.7
33.9
39
7
M46.2
ICD-10 Finland
Osteomyelitis of vertebra
+∞
33.8
32
*
TPH04
NOMESCO Finland
Cathetrisation of vein
4.4
33.2
149
483
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
54.1
33.2
39
8
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
7.0
32.6
87
154
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.6
32.0
131
385
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
6.5
30.2
85
161
WX408
NOMESCO Finland
General anesthesy, balanced
3.8
28.8
156
585
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
5.2
28.6
99
240
R50.9
ICD-10 Finland
Fever, unspecified
4.8
28.0
105
277
A40.8
ICD-10 Finland
Other streptococcal sepsis
41.2
27.6
34
9
A02BC02
ATC
pantoprazole; systemic
3.5
27.3
287
1760
N02BE01
ATC
paracetamol; systemic, rectal
5.6
27.2
353
2599
J01MA12
ATC
levofloxacin; systemic
3.9
26.1
130
446
C03CA01
ATC
furosemide; systemic
3.3
25.6
175
770
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.6
25.1
99
272
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.2
24.9
110
337
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.7
24.6
128
453
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
+∞
22.1
21
*
B01AB05
ATC
enoxaparin; parenteral
3.1
22.1
161
722
R4110
NOMESCO Finland
Physiotherapy
3.2
21.7
147
625
JN4BD
NOMESCO Finland
Extensive body CT
4.2
21.6
92
269
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
9.8
21.5
44
50
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
36.1
21.4
27
8
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
53.3
21.4
25
5
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.2
21.3
141
589
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
30.1
21.3
28
10
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
39.7
21.0
26
7
J01DB01
ATC
cefalexin; oral
3.7
21.0
332
2449
TPH07
NOMESCO Finland
Cathetrisation of artery
4.5
20.6
79
208
B18.2
ICD-10 Finland
Chronic viral hepatitis C
34.7
20.5
26
8
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
51.0
20.4
24
5
L28
ICPC
Limited function/disability (L)
3.9
20.2
94
296
7227C
ICD-9 Finland
Intervertebral disk disorders, Intervertebral disk disorder with myelopathy[SYNDROMA ISCHIADICUM]
+∞
20.0
19
*
A46
ICD-10 Finland
Erysipelas
3.7
19.8
100
337
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
26.3
19.8
27
11
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
5.0
19.7
67
155
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
+∞
18.9
18
*
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
+∞
18.9
18
*
J01CF02
ATC
cloxacillin; systemic
11.2
18.6
35
34
M03BC01
ATC
orphenadrine (citrate); systemic
3.5
18.3
97
336
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.9
18.3
143
653
M03BX02
ATC
tizanidine; oral
2.6
18.2
230
1398
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.7
18.0
186
1004
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
8.3
17.9
40
53
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
+∞
17.8
17
*
X59
ICD-10 Finland
Exposure to unspecified factor
3.4
17.5
94
330
M54.3
ICD-10 Finland
Sciatica
15.8
17.4
28
19
N02AJ06
ATC
codeine and paracetamol; systemic
2.7
17.1
153
752
JN3AD
NOMESCO Finland
Abdominal CT examination
5.0
17.1
57
129
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
23.2
17.1
24
11
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
5.6
16.9
51
103
A41.8
ICD-10 Finland
Other specified sepsis
10.2
16.8
33
35
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
177.4
16.6
17
*
J01CF05
ATC
flucloxacillin; systemic
6.7
16.0
41
67
ABC26
NOMESCO Finland
Open discectomy of lumbar spine
+∞
15.7
15
*
NA1DG
NOMESCO Finland
Cervical spine very extensive MRI examination with high intensity magnet
+∞
15.7
15
*
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
30.0
15.3
20
7
AA1AD
NOMESCO Finland
CT of head and brain
2.7
15.3
123
562
TPX10
NOMESCO Finland
Implantation of vascular injection port
7.8
14.9
34
47
SPAT1255
SPAT
Intravenous administration of medicine
4.8
14.7
50
115
M46.5
ICD-10 Finland
Other infective spondylopathies
+∞
14.7
14
*
TKC20
NOMESCO Finland
Catheterisation of bladder
4.1
14.6
59
162
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
17.9
14.5
22
13
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.4
13.9
164
913
M43.1
ICD-10 Finland
Spondylolisthesis
55.5
13.9
16
*
J01MA02
ATC
ciprofloxacin; systemic
2.3
13.8
183
1080
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
9.3
13.7
28
32
ZXA00
NOMESCO Finland
Right side
2.6
13.7
125
606
A06AD11
ATC
lactulose; oral
3.2
13.7
79
287
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.6
13.7
65
205
H02AB06
ATC
prednisolone; systemic
2.3
13.6
194
1182
A28
ICPC
Limited function/disability NOS
2.9
13.6
91
367
M54
ICD-10 Finland
Dorsalgia
4.3
13.5
52
136
M54.1
ICD-10 Finland
Radiculopathy
29.5
13.1
17
6
Z49.1
ICD-10 Finland
Extracorporeal dialysis
12.2
13.0
23
20
N17.9
ICD-10 Finland
Acute renal failure, unspecified
5.4
12.9
39
79
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.4
12.8
66
221
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
7.8
12.7
29
40
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.6
12.7
59
182
72510
ICD-8 Finland
Displacement of intervertebral disk, Lumbalis cum prolapsu disci
+∞
12.6
12
*
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
+∞
12.6
12
*
L17
ICPC
Foot/toe symptom/complaint
2.6
12.5
106
490
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
3.3
12.4
68
237
M54.2
ICD-10 Finland
Cervicalgia
6.5
12.4
32
53
N06AX21
ATC
duloxetine; oral
4.3
12.3
46
117
J01XX08
ATC
linezolid; systemic
38.9
12.3
15
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.9
12.2
80
316
N05CF01
ATC
zopiclone; oral
2.3
12.2
139
751
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.4
12.2
135
716
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.9
12.1
79
311
WX402
NOMESCO Finland
General anaesthesia
3.0
12.1
75
285
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.5
12.0
116
576
M25.5
ICD-10 Finland
Pain in joint
2.5
12.0
107
508
F15.1
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use
48.3
12.0
14
*
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
9.4
11.9
24
27
X58
ICD-10 Finland
Exposure to other specified factors
3.3
11.9
63
216
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.6
11.8
95
426
R33
ICD-10 Finland
Retention of urine
3.4
11.7
60
200
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.4
11.7
125
650
WX892
NOMESCO Finland
Monitored bed care
3.8
11.6
51
150
M79.6
ICD-10 Finland
Pain in limb
2.3
11.6
132
708
NAS20
NOMESCO Finland
Incision and debridement of infection of vertebra, unspecified
+∞
11.5
11
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
15.7
11.4
18
12
M01AB05
ATC
diclofenac; systemic, rectal
2.1
11.4
244
1729
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
36.2
11.3
14
*
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
7.5
11.2
26
37
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
4.1
11.2
44
117
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
25.9
11.2
15
6
C08CA01
ATC
amlodipine; oral
2.2
11.2
164
985
R52.0
ICD-10 Finland
Acute pain
9.7
11.2
22
24
N05BA01
ATC
diazepam; systemic, rectal
3.1
11.1
64
232
M01AE03
ATC
ketoprofen; systemic, rectal
2.2
11.1
153
893
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
6.2
11.0
29
50
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
11.0
10.9
20
19
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
5.4
10.9
32
63
TK800
NOMESCO Finland
Hemodialysis
7.1
10.9
26
39
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.9
10.8
45
127
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.6
10.7
50
155
A40.1
ICD-10 Finland
Sepsis due to streptococcus, group B
61.7
10.7
12
*
WX110
NOMESCO Finland
Local anesthesy
2.1
10.7
253
1844
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
10.5
10.6
20
20
N06AA09
ATC
amitriptyline; systemic
3.9
10.6
44
124
NA3CM
NOMESCO Finland
Lumbar spine extensive MRI examination with 3 Tesla magnet
113.0
10.5
11
*
NAW10
NOMESCO Finland
Reoperation for superficial infection in in surgery of spine or neck
+∞
10.5
10
*
M45
ICD-10 Finland
Ankylosing spondylitis
+∞
10.5
10
*
N05AH04
ATC
quetiapine; oral
2.9
10.4
69
272
L86
ICPC
Back syndrome with radiating pain
6.6
10.3
26
42
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
5.4
10.2
30
59
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
15.1
10.1
16
11
R53
ICD-10 Finland
Malaise and fatigue
2.5
10.0
84
382
M47.82
ICD-10 Finland
Other spondylosis, cervical region
26.8
9.9
13
5
M13.9
ICD-10 Finland
Arthritis, unspecified
3.8
9.7
41
117
A11CC03
ATC
alfacalcidol; systemic
7.5
9.6
22
31
ZXA05
NOMESCO Finland
Left side
2.2
9.6
111
592
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
4.5
9.6
33
78
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
3.1
9.5
53
186
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.6
9.5
43
130
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
18.1
9.5
14
8
M00.0
ICD-10 Finland
Staphylococcal arthritis and polyarthritis
102.4
9.5
10
*
Z72.2
ICD-10 Finland
Drug use
102.4
9.5
10
*
S97
ICPC
Chronic ulcer skin
3.9
9.4
38
104
NE1AA
NOMESCO Finland
Pelvis X-ray examination
4.0
9.4
37
99
9211
FHL
Exploration or removal of diskusprolapse
+∞
9.4
9
*
XF400
NOMESCO Finland
ECG with 12 standard connections
2.4
9.4
85
400
A01
ICPC
Pain general/multiple sites
4.3
9.3
34
85
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.0
9.2
184
1225
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.8
9.2
38
107
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
7.3
9.2
21
30
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.5
9.0
42
130
B01AB10
ATC
tinzaparin; parenteral
3.8
9.0
38
109
WX002
NOMESCO Finland
Sedation and analgesia
2.3
8.9
93
471
M54.8
ICD-10 Finland
Other dorsalgia
8.9
8.9
18
21
C07AB07
ATC
bisoprolol; oral
1.9
8.9
200
1386
M00.9
ICD-10 Finland
Pyogenic arthritis, unspecified
11.1
8.9
16
15
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
5.1
8.9
27
56
B03XA02
ATC
darbepoetin alfa; parenteral
7.5
8.8
20
28
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.6
8.8
39
116
N03AE01
ATC
clonazepam; systemic
4.9
8.8
28
61
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
51.2
8.7
10
*
M01AH05
ATC
etoricoxib; oral
1.9
8.7
196
1356
I50.9
ICD-10 Finland
Heart failure, unspecified
2.5
8.6
74
339
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.0
8.5
130
772
M47.9
ICD-10 Finland
Spondylosis, unspecified
28.2
8.5
11
*
P19
ICPC
Drug abuse
20.6
8.5
12
6
S18
ICPC
Laceration/cut
1.9
8.5
170
1120
M04AA01
ATC
allopurinol; systemic
2.5
8.5
73
335
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
92.0
8.4
9
*
M43.0
ICD-10 Finland
Spondylolysis
92.0
8.4
9
*
M46.0
ICD-10 Finland
Spinal enthesopathy
92.0
8.4
9
*
R60.0
ICD-10 Finland
Localized oedema
2.9
8.4
52
197
N06AX11
ATC
mirtazapine; oral
2.1
8.4
113
637
M47.1
ICD-10 Finland
Other spondylosis with myelopathy
+∞
8.4
8
*
ABC60
NOMESCO Finland
Decompression of cervical spinal cord
+∞
8.4
8
*
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
9.8
8.4
16
17
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.4
8.2
78
375
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.8
8.2
34
96
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
7.1
8.2
19
28
J01DA01
ATC
[U] cefalexin; systemic
1.9
8.1
228
1686
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.0
8.1
46
164
TQW40
NOMESCO Finland
Remowal of suture of skin
3.5
8.1
37
113
Z49.0
ICD-10 Finland
Preparatory care for dialysis
12.1
8.1
14
12
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
34.1
8.1
10
*
SPAT1254
SPAT
Administration of medicine
2.6
8.1
63
274
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.9
8.1
32
87
T36
ICD-10 Finland
Poisoning by systemic antibiotics
5.6
8.0
22
41
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.4
7.9
38
121
UJF32
NOMESCO Finland
Coloscopy
2.1
7.9
107
605
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
7.9
118
692
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
3.3
7.9
39
127
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
7.9
106
595
UKC02
NOMESCO Finland
Cystoscopy
2.2
7.8
84
430
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
15.4
7.8
12
8
NAU20
NOMESCO Finland
Removal of internal fixation device from spine or neck
45.9
7.7
9
*
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.4
7.7
36
113
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
6.4
7.6
19
31
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
10.3
7.6
14
14
JN4AD
NOMESCO Finland
Body CT examination
2.9
7.6
47
178
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.4
7.5
68
320
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.3
7.5
70
334
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
7.9
7.5
16
21
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
81.6
7.4
8
*
N05BA04
ATC
oxazepam; oral
2.1
7.4
91
491
K04.5
ICD-10 Finland
Chronic apical periodontitis
2.1
7.4
98
546
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
5.4
7.4
21
41
XF600
NOMESCO Finland
Bloodpressure measurement
3.3
7.3
36
117
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.3
7.3
26
64
WX704
NOMESCO Finland
Intubation
3.4
7.3
34
106
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
5.6
7.3
20
37
NF1AA
NOMESCO Finland
Hip X-ray examination
3.0
7.3
42
152
TQW11
NOMESCO Finland
Vacuum treatment of wound
6.0
7.3
19
33
F19.30
ICD-10 Finland
Withdrawal symptoms caused by several drugs in combination and by other psychoactive substances uncomplicated
+∞
7.3
7
*
F15.2
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, dependence syndrome
+∞
7.3
7
*
M60.0
ICD-10 Finland
Infective myositis
+∞
7.3
7
*
ABC66
NOMESCO Finland
Decompression of lumbal spinal channel
+∞
7.3
7
*
R06.0
ICD-10 Finland
Dyspnoea
2.1
7.3
94
519
SPAT1212
SPAT
Extensive examination of musculoskeletal system
3.5
7.3
33
101
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.0
7.2
113
671
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
6.8
7.2
17
26
L04AA13
ATC
leflunomide; oral
8.2
7.2
15
19
WX872
NOMESCO Finland
Intensive care
3.3
7.1
35
114
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
4.2
7.1
26
66
D64.9
ICD-10 Finland
Anaemia, unspecified
2.6
7.1
54
230
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
3.7
7.1
30
87
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
4.2
7.0
25
62
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.3
7.0
66
314
M70.6
ICD-10 Finland
Trochanteric bursitis
3.1
7.0
39
137
N05CD07
ATC
temazepam; oral
2.5
6.9
56
249
I10
ICD-10 Finland
Essential (primary) hypertension
1.8
6.9
236
1814
B01AA03
ATC
warfarin; systemic
2.0
6.9
98
562
R52.2
ICD-10 Finland
Other chronic pain
6.9
6.9
16
24
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.9
6.9
41
153
M01AH01
ATC
celecoxib; oral (coxibs)
2.3
6.9
66
320
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.2
6.9
76
392
R02
ICPC
Shortness of breath/dyspnoea
2.6
6.8
48
198
J01MA14
ATC
moxifloxacin; systemic
2.6
6.8
48
198
EBA15
NOMESCO Finland
Extraction of large number of teeth
4.0
6.8
26
69
N30.0
ICD-10 Finland
Acute cystitis
2.6
6.8
49
202
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
40.8
6.8
8
*
F11.29
ICD-10 Finland
Addiction caused by opiates UNS
40.8
6.8
8
*
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
40.8
6.8
8
*
IAB10
NOMESCO Finland
Psychiatric consultation concerning substance abuse
40.8
6.8
8
*
D07AC01
ATC
betamethasone; topical
1.9
6.7
127
805
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
23.0
6.7
9
*
NA2DG
NOMESCO Finland
Thoracal spine very extensive MRI examination with high intensity magnet
23.0
6.7
9
*
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
5.7
6.7
18
33
WW500
NOMESCO Finland
Blood transfusion
4.0
6.6
25
66
S29
ICPC
Skin symptom/complaint other
2.2
6.6
66
325
SPAT1229
SPAT
Assessment of need for aid
3.0
6.6
37
131
J01CA04
ATC
amoxicillin; systemic
1.8
6.5
280
2293
M10.0
ICD-10 Finland
Idiopathic gout
4.4
6.5
22
52
J45.9
ICD-10 Finland
Asthma, unspecified
2.2
6.5
65
319
F10.25
ICD-10 Finland
Alcohol dependence continuous use
7.6
6.5
14
19
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
7.6
6.5
14
19
M53.1
ICD-10 Finland
Cervicobrachial syndrome
3.6
6.5
27
78
F11.25
ICD-10 Finland
Relationship caused by opiates continuously used
71.0
6.4
7
*
N02AA03
ATC
hydromorphone; systemic, rectal
71.0
6.4
7
*
R4120
NOMESCO Finland
Occupational therapy
3.5
6.4
28
84
V03AE01
ATC
polystyrene sulfonate; oral
6.7
6.4
15
23
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.3
6.4
60
286
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.6
6.4
27
79
F51.0
ICD-10 Finland
Nonorganic insomnia
2.7
6.3
42
168
QD9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in lower extremities, unspecified
18.4
6.3
9
5
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.1
6.3
32
108
F19.25
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances continuously used
+∞
6.3
6
*
72880
ICD-8 Finland
Vertebrogenic pain syndrome, Radicula syndrome of lower limbs
+∞
6.3
6
*
NA3DM
NOMESCO Finland
Lumbar spine very extensive MRI examination with 3 Tesla magnet
+∞
6.3
6
*
NAG65
NOMESCO Finland
Anterior and posterior fusion of lumbar spine
+∞
6.3
6
*
NA6CG
NOMESCO Finland
Sacro-iliac joint extensive MRI examination with high intensity magnet
+∞
6.3
6
*
NA3SA
NOMESCO Finland
Lumbar spine X-ray examination in standing position
27.1
6.2
8
*
F19.24
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances active addiction
27.1
6.2
8
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.2
6.2
68
349
Z02.7
ICD-10 Finland
Issue of medical certificate
3.5
6.2
27
81
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
4.8
6.2
19
41
L02
ICPC
Back symptom/complaint
3.2
6.2
30
98
Z50.1
ICD-10 Finland
Other physical therapy
3.6
6.2
26
76
V49.9
ICD-10 Finland
Car occupant [any] injured in unspecified traffic accident
5.1
6.1
18
37
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.9
6.1
94
552
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.9
6.1
102
618
QBB05
NOMESCO Finland
Revision of wound of skin of trunk
12.8
6.1
10
8
WVA20
NOMESCO Finland
Medicine administration
6.9
6.1
14
21
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
10.3
6.1
11
11
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
10.3
6.1
11
11
QCB05
NOMESCO Finland
Revision of wound of skin of upper limb
10.3
6.1
11
11
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
100
71
18.00
113.78
1.6
1.5
—
—
—
0
0
117
237
6.39
58.30
2.3
1.5
—
—
—
0
0
322
1553
5.16
53.94
15.9
5.8
61.0
57.8
%
5.05
311
1475
323
1583
5.07
52.39
16.6
5.9
23.6
26.7
%
5.43
313
1488
161
506
4.47
46.93
4.4
2.5
18.6
23.3
%
3.36
142
435
84
153
6.57
46.03
2.2
2.1
1.0
3.6
ug/l
0.78
74
136
125
330
4.92
45.37
7.4
4.0
5.8
5.8
kpa
0.02
120
314
84
157
6.39
44.81
11.9
4.7
23.6
24.2
mmol/l
0.55
79
145
161
522
4.31
44.73
4.4
2.5
2.1
2.3
g/l
3.00
151
480
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
71
112
7.38
44.57
3.9
2.8
0.3
0.4
u/ml
0.66
39
60
302
1523
4.23
44.10
12.6
6.2
1.2
1.2
mmol/l
0.78
284
1373
167
570
4.14
42.98
4.6
2.5
10.3
13.0
umol/l
4.66
161
528
122
329
4.77
42.93
8.2
4.0
1.5
2.0
mmol/l
0.63
106
254
341
1897
4.72
42.75
19.7
9.4
4.5
4.1
e9/l
2.00
307
1668
67
104
7.44
42.62
1.8
1.4
—
—
—
0
0
294
1482
4.05
42.32
11.4
5.0
32.1
35.0
g/l
10.73
283
1379
122
337
4.64
41.54
15.8
7.8
13.0
10.5
mmol/l
2.63
116
318
210
859
3.80
41.19
3.3
2.1
3.1
3.1
mg/l
0.05
183
729
114
301
4.78
41.04
9.1
8.2
1.3
1.4
mmol/l
0.20
109
290
313
1673
4.12
40.68
16.3
7.1
1.2
1.2
mmol/l
0.61
274
1388
325
1786
4.26
40.46
11.3
6.5
11.4
12.5
umol/l
0.71
318
1699
148
487
4.09
39.69
12.3
6.3
1.1
1.0
mmol/l
2.94
138
451
75
145
6.04
38.41
2.1
2.9
—
—
—
0
0
163
590
3.82
37.86
2.4
1.8
—
—
—
0
0
162
588
3.80
37.41
5.2
3.4
0.8
0.8
mmol/l
0.43
153
558
107
307
4.30
34.15
3.0
2.7
64.2
66.1
g/l
1.38
99
282
127
417
3.89
33.55
9.9
7.9
11.8
12.1
kpa
0.27
116
408
127
417
3.89
33.55
9.9
7.9
5.2
5.1
kpa
0.46
117
408
79
185
5.00
32.47
1.9
2.1
1.6
1.6
g/l
0.16
74
166
34
31
11.81
32.38
1.2
1.2
55.5
44.9
u/l
0.44
29
19
81
195
4.88
32.20
1.8
1.4
—
—
—
0
0
254
1316
3.24
31.77
4.8
2.6
202.2
167.8
ug/l
0.79
232
1191
332
2022
3.73
31.57
9.8
4.9
6.9
6.9
mmol/l
0.16
324
1900
225
1090
3.21
31.55
6.3
3.3
38.0
35.4
u/l
0.30
215
1044
123
411
3.78
31.47
2.3
1.8
—
—
—
0
0
125
424
3.74
31.26
10.1
7.9
0.8
1.4
mmol/l
0.69
100
338
365
2380
4.36
30.93
8.7
3.7
25.6
13.2
mm/h
17.32
356
2148
92
253
4.35
30.86
5.5
4.0
138.4
87.5
ng/l
1.73
85
216
150
578
3.44
30.73
2.7
2.0
30.9
29.8
s
1.58
145
565
47
71
7.30
30.38
1.9
1.4
54212.2
22988.5
e6/l
0.44
30
51
40
51
8.54
29.86
1.3
1.4
—
—
—
0
0
209
1000
3.10
29.45
2.7
2.0
430.0
335.9
u/l
0.15
194
935
162
673
3.25
29.09
2.1
1.8
1210.4
1113.6
nmol/l
0.61
126
502
244
1280
3.07
29.05
5.9
3.1
—
—
—
0
0
118
405
3.63
28.76
2.3
1.7
—
—
—
0
0
104
335
3.77
27.80
3.3
2.1
0.2
0.2
g/l
0.56
94
309
269
1514
3.04
27.78
6.2
3.9
—
—
—
0
0
235
1239
2.96
27.19
3.5
2.1
74.2
76.9
nmol/l
0.76
213
1084
371
2563
4.08
26.15
22.5
7.7
103.0
79.7
u/l
7.84
362
2394
198
977
2.89
25.52
5.6
3.1
0.6
0.5
e6/l
0.28
163
746
63
149
4.78
25.36
2.2
2.1
4.1
3.8
g/l
0.82
46
111
63
150
4.74
25.15
2.2
2.1
8.3
7.3
g/l
2.88
47
114
63
150
4.74
25.15
2.2
2.1
—
—
—
0
0
108
380
3.45
25.03
5.4
2.6
9.8
9.8
umol/l
0.01
98
339
47
87
5.94
24.88
1.5
1.5
—
—
—
0
0
73
197
4.25
24.84
12.1
10.5
—
—
—
0
0
70
185
4.32
24.47
11.9
11.6
24.2
24.7
mmol/l
0.54
64
173
26
24
11.46
24.44
1.7
1.7
6.0
17.0
u/l
0.64
15
11
200
1010
2.82
24.42
3.8
2.4
50.9
58.0
u/l
2.35
190
937
60
141
4.78
24.31
2.2
2.1
10.7
10.6
g/l
0.03
51
121
171
802
2.87
23.94
4.4
2.4
—
—
—
0
0
94
315
3.53
23.39
2.9
2.1
28.6
183.2
u/l
0.51
79
266
42
74
6.18
23.35
1.4
1.3
—
—
—
0
0
42
74
6.18
23.35
1.4
1.3
—
—
—
0
0
59
142
4.65
23.19
2.2
2.2
3.9
3.2
g/l
3.32
47
114
58
139
4.66
22.91
2.4
2.4
0.5
0.9
g/l
0.54
51
119
133
561
2.98
22.44
4.4
2.9
2.2
1.7
e6/l
0.31
77
319
43
84
5.57
21.45
1.7
1.3
—
—
—
0
0
53
126
4.65
21.10
2.0
3.1
39.6
31.6
mg/l
0.72
43
105
178
900
2.66
20.98
4.4
2.8
4647.0
7062.8
umol/l
0.31
157
783
52
126
4.55
20.20
2.0
3.0
56.6
121.3
mg/l
0.69
41
102
41
84
5.29
19.39
2.9
3.3
30.5
37.0
umol/l
1.22
35
76
44
97
4.94
19.14
1.6
1.2
—
—
—
0
0
129
581
2.74
18.84
4.2
2.8
1.8
1.2
e6/l
0.57
77
335
51
129
4.35
18.73
1.5
2.1
32.5
37.0
g/l
3.84
46
106
44
99
4.83
18.68
1.5
1.5
0.0
0.0
iu/ml
—
10
19
71
229
3.51
18.52
2.3
1.5
—
—
—
0
0
236
1424
2.44
18.42
2.8
2.0
93.4
93.8
pmol/l
0.05
137
734
42
96
4.74
17.48
1.5
1.3
—
—
—
0
0
250
1573
2.39
17.41
7.1
4.7
0.0
0.0
estimate
0.00
46
310
195
1105
2.39
17.22
3.9
3.2
3015.0
1633.1
ng/l
1.57
167
970
251
1588
2.38
17.17
5.1
3.4
0.0
0.0
estimate
0.50
43
293
248
1561
2.37
17.17
5.0
3.4
0.0
0.0
estimate
0.00
45
303
140
685
2.54
17.06
5.2
3.6
567.8
379.6
ng/l
0.30
123
570
109
478
2.71
16.55
31.5
26.4
2.0
1.4
inr
—
10
73
17
15
11.75
16.30
1.5
1.0
494.3
244.7
iu/ml
0.66
17
15
132
641
2.52
16.23
1.9
1.7
2.1
1.5
mg/l
0.60
114
504
50
149
3.66
14.60
5.7
4.7
1.5
1.5
%
0.11
45
144
155
850
2.28
14.20
2.3
1.5
17.6
20.5
nmol/l
2.07
139
707
402
3317
3.87
13.85
56.0
14.4
33.5
28.0
mg/l
3.38
386
2639
90
391
2.64
13.72
5.8
3.0
—
—
—
0
0
27
53
5.37
13.33
1.8
1.5
122.6
97.4
u/ml
—
5
10
258
1769
2.13
13.06
3.2
2.5
—
—
—
0
0
18
24
7.78
12.79
2.8
1.4
—
—
—
0
0
21
35
6.25
12.24
1.6
1.5
86.1
66.5
%
2.15
12
28
181
1121
2.05
11.67
5.4
3.6
2.3
2.3
mmol/l
1.46
163
979
31
78
4.20
11.41
5.3
5.6
220.0
359.2
iu/ml
—
7
11
308
2323
2.12
11.33
3.9
3.4
14.9
15.0
pmol/l
0.04
273
2050
290
2150
2.05
11.03
6.8
3.0
89.5
57.0
u/l
3.55
278
1977
27
63
4.50
10.92
1.2
1.2
—
—
—
0
0
26
62
4.40
10.24
1.2
1.1
250.2
357.8
u/ml
0.79
16
32
56
222
2.75
10.09
6.0
3.7
1.7
2.3
mmol/l
0.42
43
164
58
239
2.65
9.69
6.2
3.6
5.1
5.2
kpa
0.69
53
221
70
319
2.42
9.48
2.3
2.3
7.9
7.7
ug/l
0.03
61
282
81
397
2.28
9.28
1.4
1.2
28.0
14.0
u/ml
0.34
18
148
13
7
19.09
8.98
1.1
1.0
—
—
—
0
0
362
3030
2.17
8.44
53.1
15.9
36.9
40.1
%
9.83
229
2059
198
1373
1.81
8.33
5.9
3.6
50.5
77.1
ng/l
0.51
170
1025
83
430
2.15
8.26
1.4
1.2
46.2
39.0
iu/ml
0.21
31
140
15
27
5.72
8.07
1.9
1.3
17959.6
384921.9
e6/l
—
8
21
54
239
2.44
7.76
10.1
6.8
24.8
24.2
mmol/l
0.54
48
232
37
139
2.82
7.36
1.4
2.1
44.7
37.5
u/l
0.98
29
126
12
19
6.47
7.28
1.1
1.3
—
—
—
0
0
350
2950
1.96
7.16
5.0
4.1
2.1
2.0
mu/l
0.20
324
2606
10
14
7.29
6.72
1.0
1.0
—
—
—
0
0
109
671
1.83
6.51
5.4
3.8
1.0
1.0
kg/l
0.59
19
99
34
131
2.73
6.47
2.6
1.6
—
—
—
0
0
16
38
4.33
6.34
1.5
1.4
—
—
—
0
0
29
104
2.92
6.29
1.3
1.8
—
—
—
0
0
118
757
1.77
6.10
2.2
1.8
434.2
16060018.1
pmol/l
0.79
101
604
73
402
1.98
6.09
4.3
4.6
15.9
36.3
ug/l
0.46
65
338
35
143
2.57
5.95
2.8
1.7
—
—
—
0
0
400
3610
2.38
5.80
28.4
10.2
28.4
27.1
u/l
0.55
394
3453
23
76
3.14
5.73
3.5
2.6
16.0
16.1
%
—
10
42
70
388
1.96
5.72
2.8
1.9
1.6
1.6
%
0.39
61
337
9
8
11.45
5.31
1.7
1.3
—
—
—
0
0
169
1236
1.60
5.18
5.7
3.6
—
—
—
0
0
21
72
3.01
4.94
2.0
2.3
—
—
—
0
0
98
630
1.72
4.94
4.4
3.3
2.5
2.4
mmol/l
0.52
82
555
15
42
3.66
4.81
2.1
1.4
205850.0
24349.3
e6/l
—
8
26
14
38
3.77
4.68
4.9
3.4
—
—
—
0
0
7
5
14.20
4.59
1.6
1.6
—
—
—
0
0
9
14
6.54
4.00
2.7
1.4
—
—
—
0
0
15
48
3.20
3.96
2.5
1.7
91.3
88.9
%
1.29
15
48
11
29
3.87
3.82
1.4
1.2
—
—
—
0
0
20
78
2.64
3.77
2.7
2.4
123.3
130.9
g/l
0.50
14
65
20
79
2.61
3.68
1.4
1.7
—
—
—
0
0
6
6
10.12
3.50
20.5
7.8
4.8
6.0
mmol/l
—
6
6
13
42
3.16
3.39
2.0
1.5
—
—
—
0
0
9
18
5.08
3.38
1.2
1.6
—
—
—
0
0
16
59
2.78
3.36
1.1
1.1
—
—
—
0
0
13
43
3.09
3.27
2.0
1.5
—
—
—
0
0
13
43
3.09
3.27
2.0
1.5
—
—
—
0
0
13
43
3.09
3.27
2.0
1.5
—
—
—
0
0
13
43
3.09
3.27
2.0
1.5
—
—
—
0
0
13
44
3.01
3.16
2.0
1.5
—
—
—
0
0
154
1204
1.43
3.10
6.0
4.2
24.0
9.0
mg/mmol
1.11
109
787
17
68
2.56
3.08
2.1
1.2
2.5
55.0
e6/l
0.63
12
56
6
8
7.58
3.06
1.3
2.1
1.1
1.2
mmol/l
—
6
8
16
64
2.56
2.90
7.4
3.1
60.2
58.0
%
0.37
16
64
7
13
5.45
2.88
1.1
1.2
—
—
—
0
0
16
65
2.52
2.82
1.4
1.2
4.7
3.8
mmol/l
1.16
16
60
10
31
3.28
2.79
1.1
1.0
—
—
—
0
0
9
23
3.97
2.79
1.3
1.1
2.2
1.9
mmol/l
—
9
23
47
290
1.70
2.74
7.5
3.4
1.2
1.2
mmol/l
0.03
47
246
15
60
2.55
2.73
5.1
2.8
4.3
4.4
e9/l
0.03
15
60
20
94
2.18
2.59
1.4
1.7
—
—
—
0
0
120
923
1.41
2.58
1.8
1.6
1.4
1.4
mmol/l
0.44
100
737
14
56
2.55
2.55
1.1
1.2
—
—
—
0
0
16
69
2.37
2.51
2.2
1.4
—
—
—
0
0
18
83
2.22
2.44
1.4
1.1
—
—
—
0
0
10
249
0.39
2.43
1.5
1.8
—
—
—
0
0
11
40
2.80
2.39
5.5
2.7
—
—
—
0
0
81
587
1.47
2.39
1.4
1.2
0.8
1.1
u/ml
1.03
22
160
18
84
2.19
2.38
1.4
1.1
—
—
—
0
0
13
52
2.55
2.38
1.5
1.8
30.3
33.3
pg
1.22
13
52
16
71
2.30
2.37
1.1
1.8
—
—
—
0
0
26
141
1.90
2.33
1.3
1.3
258.6
195.8
u/ml
0.29
26
132
11
41
2.73
2.29
1.1
1.8
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
18
3.93
2.26
1.1
1.2
—
—
—
0
0
6
14
4.33
2.15
3.8
1.4
106.7
62.4
ug/l
—
6
14
29
169
1.77
2.10
1.4
1.3
—
80.3
—
0
11
20
103
1.99
2.09
3.5
2.3
45.6
71.5
u/ml
0.27
20
96
19
96
2.02
2.08
1.2
1.7
—
—
—
0
0
347
3214
1.40
2.07
8.2
6.1
42.1
40.7
mmol/mol
1.53
324
2940
31
187
1.71
2.00
2.5
2.5
—
21.0
—
0
11
7
21
3.37
1.97
1.6
1.4
—
—
—
0
0
33
204
1.67
1.95
4.8
2.6
0.3
0.2
e6/l
0.05
33
197
107
847
1.35
1.89
6.4
3.6
0.0
0.0
estimate
0.69
37
293
7
22
3.22
1.88
1.3
1.1
—
—
—
0
0
349
3260
1.36
1.78
45.9
13.8
75.4
77.4
ml/min/173m2
0.73
323
2687
6
18
3.36
1.75
5.3
4.3
—
—
—
0
0
8
30
2.70
1.73
1.1
1.8
—
—
—
0
0
7
24
2.95
1.73
1.3
1.4
—
—
—
0
0
7
24
2.95
1.73
1.3
1.4
—
—
—
0
0
6
19
3.19
1.66
3.0
2.3
—
—
—
0
0
6
20
3.03
1.58
1.3
1.5
—
—
—
0
0
6
20
3.03
1.58
1.2
1.2
—
—
—
0
0
6
20
3.03
1.58
1.3
1.5
—
—
—
0
0
6
20
3.03
1.58
1.2
1.2
—
—
—
0
0
5
15
3.36
1.52
1.2
2.1
978.6
2431.3
u/ml
—
5
15
5
15
3.36
1.52
1.2
1.1
—
—
—
0
0
7
27
2.62
1.52
1.3
1.4
—
—
—
0
0
7
27
2.62
1.52
1.1
1.6
—
—
—
0
0
7
27
2.62
1.52
1.1
1.6
—
—
—
0
0
11
51
2.19
1.51
1.0
1.2
—
—
—
0
0
12
58
2.10
1.50
1.1
1.6
—
—
—
0
0
6
22
2.75
1.44
1.0
1.5
—
53.3
—
0
6
353
3335
1.31
1.41
5.5
4.7
6.3
6.1
mmol/l
1.26
315
2972
27
174
1.59
1.41
1.7
1.7
—
—
—
0
0
24
152
1.61
1.35
1.7
1.6
—
—
—
0
0
8
34
2.38
1.29
1.6
2.6
—
—
—
0
0
5
119
0.41
1.26
1.4
1.0
—
—
—
0
0
15
86
1.77
1.20
1.9
1.6
177.6
235.4
pmol/l
1.43
15
79
7
32
2.21
1.08
1.3
1.2
—
—
—
0
0
35
256
1.40
1.04
6.6
2.7
51.4
58.6
ml/min/173m2
0.43
18
108
9
48
1.89
1.01
1.6
1.7
—
—
—
0
0
18
117
1.56
0.95
1.9
1.7
44.2
39.7
nmol/l
0.41
18
112
7
37
1.91
0.94
1.1
1.1
—
—
—
0
0
6
27
2.24
0.94
1.0
1.1
—
—
—
0
0
19
126
1.53
0.93
1.5
1.2
—
—
—
0
0
6
28
2.16
0.92
1.0
1.3
—
—
—
0
0
6
28
2.16
0.92
4.2
1.3
—
—
—
0
0
8
46
1.75
0.83
1.8
1.7
—
—
—
0
0
6
32
1.89
0.82
1.2
1.0
—
—
—
0
0
19
131
1.47
0.79
1.2
1.2
232.2
127.7
iu/ml
—
5
50
9
53
1.71
0.76
2.8
2.8
17.0
23.6
u/ml
—
9
53
5
24
2.10
0.74
1.2
1.1
—
—
—
0
0
5
24
2.10
0.74
1.2
1.1
—
—
—
0
0
5
25
2.01
0.73
1.2
1.1
—
—
—
0
0
5
25
2.01
0.73
1.2
1.1
—
—
—
0
0
5
25
2.01
0.73
1.2
1.1
—
—
—
0
0
7
40
1.76
0.71
1.1
1.1
—
—
—
0
0
9
57
1.59
0.71
1.2
1.7
—
—
—
0
0
9
59
1.54
0.68
1.2
1.7
—
—
—
0
0
11
71
1.56
0.62
1.2
1.6
—
—
—
0
0
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
10
64
1.58
0.59
1.2
1.6
—
—
—
0
0
192
1799
1.12
0.55
5.3
4.9
1.8
2.6
ug/l
2.36
164
1580
7
46
1.53
0.48
1.0
1.1
—
—
—
0
0
44
376
1.19
0.46
1.3
1.4
—
—
—
0
0
356
3473
1.14
0.46
5.9
5.0
2.4
2.6
mmol/l
5.12
331
3133
7
50
1.41
0.45
1.0
1.0
—
—
—
0
0
10
71
1.42
0.39
1.2
1.3
—
—
—
0
0
10
73
1.38
0.35
1.0
1.1
—
—
—
0
0
154
1457
1.09
0.34
4.3
4.1
21.2
21.7
%
0.11
64
732
334
3264
1.10
0.34
4.9
4.0
1.3
1.3
mmol/l
0.33
305
2932
6
44
1.37
0.34
1.2
1.7
—
—
—
0
0
343
3371
1.08
0.26
5.3
4.4
1.3
1.4
mmol/l
1.48
318
3045
37
331
1.13
0.25
2.6
2.1
13.8
13.2
nmol/l
0.19
30
303
345
3396
1.08
0.23
5.5
4.5
4.2
4.5
mmol/l
4.35
324
3097
5
40
1.25
0.22
1.4
1.6
—
—
—
0
0
5
40
1.25
0.22
1.4
1.6
—
—
—
0
0
5
40
1.25
0.22
1.4
1.6
—
—
—
0
0
5
42
1.19
0.21
1.0
2.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.8
—
—
—
0
0
42
454
0.92
0.17
5.5
4.6
30.7
31.1
%
0.10
35
292
5
45
1.11
0.10
1.0
1.1
—
—
—
0
0
104
1068
0.97
0.09
2.9
3.0
0.7
0.8
ug/l
0.33
70
733
6
54
1.11
0.09
1.0
2.0
—
—
—
0
0
21
224
0.93
0.07
1.1
1.5
—
—
—
0
0
12
109
1.10
0.06
2.9
2.4
351.2
96.4
ug/min
—
7
64
43
416
1.04
0.05
17.6
6.6
—
—
—
0
0
10
96
1.04
0.00
1.0
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
8
0.00
0.00
0.0
1.1
—
116.4
—
0
8
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
4.0
—
112.4
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
70
1.00
0.00
1.1
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
9
0.00
0.00
0.0
1.1
—
163.1
—
0
9
0
9
0.00
0.00
0.0
1.0
—
24.1
—
0
9
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_DISCINFECTION and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_DISCINFECTION | 2.197 [1.72, 2.81] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.048 |
During the follow-up period (1.1.1998 — 31.12.2019), 208 out of 774 females with M13_DISCINFECTION died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_DISCINFECTION | 2.163 [1.73, 2.7] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 430 out of 1413 males with M13_DISCINFECTION died.
Mortality risk
Mortality risk for people of age
years, who have M13_DISCINFECTION.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.152% | 0.427% |
| 5 | 1.139% | 2.451% |
| 10 | 2.617% | 5.546% |
| 15 | 5.3% | 10.663% |
| 20 | 9.26% | 18.144% |
Relationships between endpoints
↥Index endpoint: M13_DISCINFECTION – Infection of intervertebral disc (pyogenic)
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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