Infection of intervertebral disc (pyogenic)

M13_DISCINFECTION

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M46.3
  • Cause of death: ICD-10 M46.3

2 out of 7 registries used, show all original rules.

481

4. Check minimum number of events

None

481

5. Include endpoints

None

481

6. Filter based on genotype QC (FinnGen only)

469

Control definitions (FinnGen only)

Control exclude
M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M46
Name in latin
Infectio disci intervertebralis (pyogenes)

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2789 1003 1779
Only index persons 2627 945 1682
Unadjusted period prevalence (%)
Whole population 0.04 0.03 0.05
Only index persons 0.05 0.03 0.06
Median age at first event (years)
Whole population 64.58 68.10 62.60
Only index persons 64.18 67.66 62.22

-FinnGen-

Key figures

All Female Male
Number of individuals 469 147 322
Unadjusted period prevalence (%) 0.12 0.05 0.15
Median age at first event (years) 67.39 68.89 66.70

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
481
Matched controls
4810
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M46.3
ICD-10 Finland
Infection of intervertebral disc (pyogenic)
+∞
307.7
480
*
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
60.0
244.4
141
33
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
29.6
213.6
155
76
M48.0
ICD-10 Finland
Spinal stenosis
62.3
189.1
107
22
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
53.4
179.5
105
25
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
40.3
177.1
112
36
M46.4
ICD-10 Finland
Discitis, unspecified
+∞
157.1
142
*
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
341.2
149.5
144
6
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
45.3
142.1
86
23
M54.5
ICD-10 Finland
Low back pain
8.9
131.9
274
621
N03AX16
ATC
[U] pregabalin
8.3
112.2
204
392
A49.9
ICD-10 Finland
Bacterial infection, unspecified
8.5
109.2
186
332
M54.9
ICD-10 Finland
Dorsalgia, unspecified
11.5
95.5
111
122
J04AB02
ATC
rifampicin; systemic
37.9
95.3
60
18
N02AA05
ATC
oxycodone; systemic
6.6
89.5
210
508
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
48.5
88.1
52
12
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
9.2
81.2
113
156
N03AX12
ATC
[U] gabapentin; oral
7.8
80.2
134
228
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
7.9
79.8
130
215
N02AX02
ATC
tramadol; systemic, rectal
5.6
75.2
311
1192
NA3DG
NOMESCO Finland
Lumbar spine very extensive MRI examination with high intensity magnet
276.8
71.4
71
*
M54.4
ICD-10 Finland
Lumbago with sciatica
7.7
69.9
113
184
A40.8
ICD-10 Finland
Other streptococcal sepsis
30.9
67.5
45
16
J01FF01
ATC
clindamycin; systemic
4.9
65.5
235
785
A41.9
ICD-10 Finland
Sepsis, unspecified
10.8
65.4
76
82
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
24.7
65.0
47
21
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
7.5
64.3
105
172
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
32.8
64.2
42
14
L03
ICPC
Low back symptom/complaint
5.1
62.6
180
501
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.8
58.9
187
560
A41.8
ICD-10 Finland
Other specified sepsis
16.3
57.0
50
34
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.6
55.8
185
570
G06.1
ICD-10 Finland
Intraspinal abscess and granuloma
+∞
53.1
50
*
TPH04
NOMESCO Finland
Cathetrisation of vein
4.4
52.8
191
625
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.5
52.0
342
1703
N02BF02
ATC
pregabalin; oral
10.7
51.4
59
62
ZXD05
NOMESCO Finland
Urgent procedure
4.1
51.2
238
929
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
5.3
49.1
118
277
R50.9
ICD-10 Finland
Fever, unspecified
4.7
47.4
140
389
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.8
47.2
132
351
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.8
45.9
129
344
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
133.0
45.7
48
*
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
8.1
45.2
65
91
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.4
44.4
146
438
N02BF01
ATC
gabapentin; oral
7.7
43.1
65
96
A46
ICD-10 Finland
Erysipelas
4.3
42.9
142
427
J01MA12
ATC
levofloxacin; systemic
3.9
41.8
170
591
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.8
41.0
174
622
N06AX21
ATC
duloxetine; oral
5.8
37.9
76
150
WX408
NOMESCO Finland
General anesthesy, balanced
3.5
37.5
188
742
J01CF05
ATC
flucloxacillin; systemic
6.5
37.4
66
115
C03CA01
ATC
furosemide; systemic
3.3
37.1
237
1084
M46.2
ICD-10 Finland
Osteomyelitis of vertebra
+∞
35.9
34
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
5.6
35.8
75
154
L28
ICPC
Limited function/disability (L)
3.8
35.3
135
444
TPX10
NOMESCO Finland
Implantation of vascular injection port
8.4
35.0
48
63
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
8.4
35.0
48
63
JN4AD
NOMESCO Finland
Body CT examination
4.2
34.5
110
318
JN3AD
NOMESCO Finland
Abdominal CT examination
4.3
34.4
103
284
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
82.5
34.4
38
5
J01CF02
ATC
cloxacillin; systemic
10.5
34.3
39
40
B01AB05
ATC
enoxaparin; parenteral
3.2
34.3
220
999
N17.9
ICD-10 Finland
Acute renal failure, unspecified
6.7
33.6
57
95
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
11.4
33.5
36
34
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
4.3
32.1
95
259
M54.8
ICD-10 Finland
Other dorsalgia
12.6
31.9
32
27
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
333.5
31.2
31
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.4
30.9
87
228
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
35.2
30.5
39
12
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.1
30.4
194
866
TKC20
NOMESCO Finland
Catheterisation of bladder
4.7
30.3
78
190
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
7.5
30.2
45
65
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
9.1
30.0
38
45
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
11.4
29.8
32
30
TPH07
NOMESCO Finland
Cathetrisation of artery
3.8
29.7
107
335
A02BC02
ATC
pantoprazole; systemic
3.5
29.6
377
2451
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.0
29.5
193
871
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
+∞
29.5
28
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
4.1
29.3
93
266
M03BC01
ATC
orphenadrine (citrate); systemic
3.5
28.9
122
424
J01MA02
ATC
ciprofloxacin; systemic
2.9
28.4
248
1301
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
8.6
28.1
37
46
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.6
27.3
109
364
JN4BD
NOMESCO Finland
Extensive body CT
3.6
26.9
108
362
R4110
NOMESCO Finland
Physiotherapy
2.9
26.9
184
844
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
5.2
26.5
59
127
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.7
26.4
67
161
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
5.6
26.3
53
104
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
33.1
26.3
34
11
A28
ICPC
Limited function/disability NOS
3.2
25.9
132
512
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
38.0
25.5
32
9
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
38.0
25.5
32
9
L86
ICPC
Back syndrome with radiating pain
6.8
25.2
41
65
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
10.6
24.9
28
28
SPAT1255
SPAT
Intravenous administration of medicine
4.5
24.6
65
161
A01
ICPC
Pain general/multiple sites
4.6
24.3
62
149
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
+∞
24.2
23
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.6
24.1
239
1308
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.1
24.0
74
206
Z3226
NOMESCO Finland
Physiotherapist
3.2
23.9
120
459
S97
ICPC
Chronic ulcer skin
4.5
23.7
62
152
X59
ICD-10 Finland
Exposure to unspecified factor
3.1
23.6
128
511
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
7.7
23.6
34
47
AA1AD
NOMESCO Finland
CT of head and brain
2.7
23.4
185
903
TK800
NOMESCO Finland
Hemodialysis
7.4
22.8
34
49
J01DB01
ATC
cefalexin; oral
3.9
22.7
424
3162
N06AA09
ATC
amitriptyline; systemic
4.6
22.6
58
140
WX402
NOMESCO Finland
General anaesthesia
2.9
22.4
129
532
N02BE01
ATC
paracetamol; systemic, rectal
5.8
21.8
454
3578
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
4.2
21.5
62
164
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
9.4
21.4
26
29
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
52.6
21.3
25
5
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
3.3
21.2
93
326
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
7.0
21.1
33
50
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.5
21.1
221
1221
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
+∞
21.0
20
*
7227C
ICD-9 Finland
Intervertebral disk disorders, Intervertebral disk disorder with myelopathy[SYNDROMA ISCHIADICUM]
+∞
21.0
20
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.4
20.9
57
144
ZXD35
NOMESCO Finland
Usual procedure
6.2
20.9
37
64
M54.3
ICD-10 Finland
Sciatica
7.1
20.7
32
48
M03BX02
ATC
tizanidine; oral
2.5
20.6
285
1781
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.6
20.4
168
826
L17
ICPC
Foot/toe symptom/complaint
2.6
20.2
161
779
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
4.9
20.1
46
101
H02AB06
ATC
prednisolone; systemic
2.4
20.0
258
1556
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.0
20.0
104
403
TQW11
NOMESCO Finland
Vacuum treatment of wound
8.5
19.8
26
32
B18.2
ICD-10 Finland
Chronic viral hepatitis C
18.7
19.8
30
17
B03XA02
ATC
darbepoetin alfa; parenteral
7.0
19.8
31
47
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
25.9
19.7
27
11
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
208.2
19.7
20
*
R33
ICD-10 Finland
Retention of urine
3.5
19.5
76
247
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
4.9
19.3
44
96
D64.9
ICD-10 Finland
Anaemia, unspecified
3.2
19.3
85
298
N02AJ06
ATC
codeine and paracetamol; systemic
2.4
19.2
213
1195
NA1DG
NOMESCO Finland
Cervical spine very extensive MRI examination with high intensity magnet
+∞
18.9
18
*
WX892
NOMESCO Finland
Monitored bed care
3.6
18.6
68
212
S18
ICPC
Laceration/cut
2.3
18.5
252
1540
WX704
NOMESCO Finland
Intubation
4.1
18.0
52
137
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
4.2
17.8
50
129
M46.5
ICD-10 Finland
Other infective spondylopathies
+∞
17.8
17
*
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
5.4
17.7
36
71
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
17.6
207
1180
M54
ICD-10 Finland
Dorsalgia
3.6
17.6
63
193
TPH40
NOMESCO Finland
Insertion of a long peripheral venous catheter
25.2
17.5
24
10
X58
ICD-10 Finland
Exposure to other specified factors
3.0
17.2
86
324
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
32.8
17.2
22
7
M54.2
ICD-10 Finland
Cervicalgia
5.0
17.1
38
81
M13.9
ICD-10 Finland
Arthritis, unspecified
3.9
17.1
54
152
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.8
17.1
97
392
R60.0
ICD-10 Finland
Localized oedema
3.1
16.9
78
280
A06AD11
ATC
lactulose; oral
2.8
16.8
99
408
A11CC03
ATC
alfacalcidol; systemic
5.8
16.7
31
56
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
4.7
16.7
40
91
N05AH04
ATC
quetiapine; oral
2.8
16.5
95
386
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
4.1
16.4
48
128
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.6
16.0
116
529
T36
ICD-10 Finland
Poisoning by systemic antibiotics
6.1
15.9
28
48
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
6.1
15.9
28
48
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
7.5
15.8
23
32
A12AA04
ATC
calcium carbonate; oral
7.5
15.8
23
32
M25.5
ICD-10 Finland
Pain in joint
2.4
15.8
146
745
ABC26
NOMESCO Finland
Open discectomy of lumbar spine
+∞
15.7
15
*
WX110
NOMESCO Finland
Infiltration anesthesia
2.3
15.7
340
2451
M54.6
ICD-10 Finland
Pain in thoracic spine
5.1
15.7
34
71
UJF32
NOMESCO Finland
Coloscopy
2.3
15.7
151
784
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
6.0
15.6
28
49
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.3
15.4
174
964
M79.6
ICD-10 Finland
Pain in limb
2.2
15.4
194
1125
WX872
NOMESCO Finland
Intensive care
3.7
15.3
51
149
R52.0
ICD-10 Finland
Acute pain
5.9
15.3
28
50
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.4
15.2
58
185
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
11.4
15.2
28
26
N05CF01
ATC
zopiclone; oral
2.2
15.0
172
958
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.7
15.0
50
146
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.1
14.9
253
1641
J01XX08
ATC
linezolid; systemic
26.0
14.8
20
8
R52.2
ICD-10 Finland
Other chronic pain
6.6
14.7
24
38
Z49.1
ICD-10 Finland
Extracorporeal dialysis
11.4
14.7
27
25
NAS20
NOMESCO Finland
Incision and debridement of infection of vertebra, unspecified
+∞
14.7
14
*
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
+∞
14.7
14
*
C07AB07
ATC
bisoprolol; oral
2.1
14.5
276
1865
C08CA01
ATC
amlodipine; oral
2.1
14.5
224
1399
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
14.4
161
885
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
4.1
14.4
41
107
WX002
NOMESCO Finland
Sedation and analgesia
2.4
14.3
122
597
ZXA05
NOMESCO Finland
Left side
2.3
14.3
142
743
Z3231
NOMESCO Finland
Registered nurse
2.2
14.3
156
849
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
5.7
14.2
27
50
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
13.2
14.0
24
19
XF400
NOMESCO Finland
ECG with 12 standard connections
2.5
13.8
104
480
J01MA14
ATC
moxifloxacin; systemic
3.1
13.8
63
224
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
5.3
13.8
28
55
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.4
13.8
53
170
M47.1
ICD-10 Finland
Other spondylosis with myelopathy
+∞
13.6
13
*
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
5.4
13.6
27
52
F15.1
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use
35.2
13.6
17
5
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.9
13.5
41
112
N05BA01
ATC
diazepam; systemic, rectal
2.8
13.5
76
304
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
12.0
13.4
24
21
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
5.0
13.2
29
61
A40.1
ICD-10 Finland
Sepsis due to streptococcus, group B
41.3
13.2
16
*
I50.9
ICD-10 Finland
Heart failure, unspecified
2.5
13.1
100
464
P19
ICPC
Drug abuse
29.3
13.0
17
6
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
13.5
13.0
22
17
M47.9
ICD-10 Finland
Spondylosis, unspecified
51.5
12.9
15
*
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
51.5
12.9
15
*
WZC00
NOMESCO Finland
Treatment plan or consultation
2.1
12.9
183
1095
M04AA01
ATC
allopurinol; systemic
2.5
12.9
98
454
NF1AA
NOMESCO Finland
Hip X-ray examination
3.0
12.8
59
211
ZXE20
NOMESCO Finland
More than three and less than five hours
2.5
12.7
89
396
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
12.6
114
569
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.3
12.6
50
163
M43.1
ICD-10 Finland
Spondylolisthesis
17.9
12.6
19
11
M01AE03
ATC
ketoprofen; systemic, rectal
2.1
12.6
183
1103
N06AX11
ATC
mirtazapine; oral
2.1
12.6
163
941
A10AB05
ATC
insulin aspart; parenteral
3.1
12.6
57
202
NA3CM
NOMESCO Finland
Lumbar spine extensive MRI examination with 3 Tesla magnet
+∞
12.6
12
*
72510
ICD-8 Finland
Displacement of intervertebral disk, Lumbalis cum prolapsu disci
+∞
12.6
12
*
M54.1
ICD-10 Finland
Radiculopathy
13.7
12.5
21
16
N03AE01
ATC
clonazepam; systemic
4.1
12.5
35
90
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.1
12.5
35
90
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.2
12.4
52
176
S76
ICPC
Skin infection other
3.6
12.4
43
129
R53
ICD-10 Finland
Malaise and fatigue
2.3
12.3
120
618
I50.0
ICD-10 Finland
Congestive heart failure
3.0
12.3
59
216
ZXE00
NOMESCO Finland
One hour or less
2.0
12.2
200
1255
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.9
12.2
37
101
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
18.6
12.1
18
10
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
5.2
12.1
25
50
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.5
11.9
83
368
E66.9
ICD-10 Finland
Obesity, unspecified
5.3
11.9
24
47
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.7
11.8
38
108
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.0
11.8
166
984
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.2
11.8
50
170
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.2
11.8
50
170
KA1AE
NOMESCO Finland
Kidney ultrasound examination
4.9
11.8
26
55
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.2
11.7
48
160
C03DA01
ATC
spironolactone; oral
2.5
11.6
81
359
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.8
11.6
36
100
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.8
11.6
36
100
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
5.0
11.6
25
52
ABC66
NOMESCO Finland
Decompression of lumbal spinal channel
+∞
11.5
11
*
9211
FHL
Exploration or removal of diskusprolapse
+∞
11.5
11
*
NAU20
NOMESCO Finland
Removal of internal fixation device from spine or neck
+∞
11.5
11
*
NAW10
NOMESCO Finland
Reoperation for superficial infection in in surgery of spine or neck
122.8
11.5
12
*
NA2DG
NOMESCO Finland
Thoracal spine very extensive MRI examination with high intensity magnet
122.8
11.5
12
*
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
3.3
11.5
45
146
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
11.5
138
771
B01AB10
ATC
tinzaparin; parenteral
2.7
11.4
64
255
SPAT1229
SPAT
Assessment of need for aid
3.2
11.3
48
163
N30.0
ICD-10 Finland
Acute cystitis
2.6
11.3
72
305
ZXA00
NOMESCO Finland
Right side
2.1
11.3
145
828
M43.0
ICD-10 Finland
Spondylolysis
36.0
11.3
14
*
N18.8
ICD-10 Finland
Other chronic renal failure
4.8
11.3
26
57
WX882
NOMESCO Finland
High dependency care
4.9
11.3
25
53
WX725
NOMESCO Finland
Noninvasive ventilation
3.8
11.3
35
97
SPAT1254
SPAT
Administration of medicine
2.4
11.1
84
386
Z2446
NOMESCO Finland
Social worker
3.2
11.1
46
154
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.6
11.1
27
62
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.5
11.0
80
361
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
2.0
10.9
146
847
M00.9
ICD-10 Finland
Pyogenic arthritis, unspecified
10.9
10.9
20
19
N19
ICD-10 Finland
Unspecified kidney failure
3.8
10.8
34
95
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.3
10.8
98
488
UKC02
NOMESCO Finland
Cystoscopy
2.2
10.8
104
531
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
28.8
10.8
14
5
M01AH01
ATC
celecoxib; oral
2.4
10.8
83
385
L70
ICPC
Infection of musculoskeletal system
22.1
10.7
15
7
Z02.7
ICD-10 Finland
Issue of medical certificate
3.3
10.7
42
136
SPAT1301
SPAT
No procedures
2.0
10.7
155
923
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.4
10.7
40
126
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
11.6
10.6
19
17
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.5
10.6
37
111
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.0
10.6
49
175
L04AA13
ATC
[U] leflunomide
10.4
10.6
20
20
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.7
10.6
62
252
N06AX16
ATC
venlafaxine; oral
2.7
10.6
61
246
M47.82
ICD-10 Finland
Other spondylosis, cervical region
14.6
10.6
17
12
R4120
NOMESCO Finland
Occupational therapy
3.2
10.5
43
143
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.6
10.5
35
102
ABC60
NOMESCO Finland
Decompression of cervical spinal cord
+∞
10.5
10
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.6
10.4
63
260
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.8
10.4
32
88
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
5.3
10.4
21
41
D07AC01
ATC
betamethasone; topical
1.9
10.4
176
1105
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.2
10.3
99
505
TQW40
NOMESCO Finland
Remowal of suture of skin
3.1
10.2
45
157
NA1AD
NOMESCO Finland
Cervical spine CT examination
3.9
10.0
30
81
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.0
10.0
140
822
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.7
9.9
55
217
M01AB05
ATC
diclofenac; systemic, rectal
1.9
9.9
299
2247
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
9.8
9.8
19
20
XF600
NOMESCO Finland
Bloodpressure measurement
3.2
9.8
41
138
WW500
NOMESCO Finland
Blood transfusion
3.4
9.8
35
107
B01AA03
ATC
warfarin; systemic
2.1
9.7
118
657
NA3SA
NOMESCO Finland
Lumbar spine X-ray examination in standing position
56.2
9.7
11
*
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
11.7
9.6
17
15
R5110, ,
SPAT
3.2
9.6
39
129
ZX120
NOMESCO Finland
Intravenous
2.6
9.5
57
234
M53.1
ICD-10 Finland
Cervicobrachial syndrome
3.3
9.5
36
114
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
7.8
9.5
21
28
M00.0
ICD-10 Finland
Staphylococcal arthritis and polyarthritis
30.7
9.4
12
*
M46.0
ICD-10 Finland
Spinal enthesopathy
+∞
9.4
9
*
NAG66
NOMESCO Finland
Posterior interbody fusion of lumbar spine, 2 vertebrae
+∞
9.4
9
*
NAG53
NOMESCO Finland
Posterior or lateral fusion of thoracic spine with fixation, more than 3 vertebraea
+∞
9.4
9
*
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
22.2
9.4
13
6
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
4.8
9.4
21
45
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.2
9.4
87
436
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.6
9.3
58
243
ZXA10
NOMESCO Finland
Bilateral
2.1
9.2
100
532
L02
ICPC
Back symptom/complaint
3.0
9.2
42
149
A04
ICPC
Weakness/tiredness general
2.3
9.2
73
342
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
2.2
9.2
86
432
E0000UV, ,
ATC
1.8
9.2
186
1226
QCB05
NOMESCO Finland
Revision of wound of skin of upper limb
11.8
9.1
16
14
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
3.0
9.1
42
150
N05BA04
ATC
oxazepam; oral
2.0
9.1
121
694
V03AE01
ATC
polystyrene sulfonate; oral
9.3
9.1
18
20
Z49.0
ICD-10 Finland
Preparatory care for dialysis
10.3
9.1
17
17
E66.8
ICD-10 Finland
Other obesity
4.0
9.1
26
68
Z72.2
ICD-10 Finland
Drug use
37.4
9.1
11
*
S29
ICPC
Skin symptom/complaint other
2.1
9.0
97
515
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
4.1
9.0
25
64
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.1
9.0
25
64
R06AE07
ATC
cetirizine; oral
1.8
9.0
174
1130
R06.0
ICD-10 Finland
Dyspnoea
1.9
9.0
136
816
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
24.5
8.9
12
5
ZZH40
NOMESCO Finland
Substitute of bone
24.5
8.9
12
5
A07EC01
ATC
sulfasalazine; oral, rectal
3.1
8.9
39
135
N03AX09
ATC
lamotrigine; oral
4.6
8.9
21
47
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
5.0
8.9
19
39
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.8
8.9
20
43
R03AC02
ATC
salbutamol; inhalant
1.8
8.9
235
1674
SPAT1263
SPAT
Sampling
1.8
8.9
192
1288
I35.0
ICD-10 Finland
Aortic (valve) stenosis
2.7
8.9
48
187
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
8.9
8.9
18
21
D07AA02
ATC
hydrocortisone; topical
2.3
8.8
69
321
SPAT1215
SPAT
Assessment of need for medical rehabilitation
4.3
8.8
23
56
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
4.0
8.8
25
65
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
8.8
88
454
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
2.3
8.8
73
349
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
50.9
8.7
10
*
ZXM20
NOMESCO Finland
Intraoperative use of computerised tomography
50.9
8.7
10
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.4
8.6
61
271
M70.6
ICD-10 Finland
Trochanteric bursitis
2.6
8.6
53
221
S10
ICPC
Boil/carbuncle
3.1
8.5
36
122
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
3.3
8.5
32
101
J01DA01
ATC
[U] cefalexin
1.8
8.5
280
2116
L88
ICPC
Rheumatoid/seropositive arthritis
4.6
8.4
20
45
F19.24
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances active addiction
91.6
8.4
9
*
N02AC04
ATC
dextropropoxyphene; oral
4.1
8.4
23
58
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
2.4
8.4
64
294
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
3.2
8.4
33
107
SPAT1262
SPAT
Handing over of treatment supplies
2.0
8.4
101
558
WX199
NOMESCO Finland
Other local analgesia
3.6
8.3
28
82
L84
ICPC
Back syndrome without radiat pain
4.0
8.3
24
63
N18.0
ICD-10 Finland
End-stage renal disease
9.7
8.3
16
17
A03
ICPC
Fever
2.3
8.3
71
343
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.6
8.3
51
212
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
6.7
8.3
20
31
Z50.1
ICD-10 Finland
Other physical therapy
3.3
8.3
32
103
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
14.8
8.2
13
9
A07EC02
ATC
mesalazine; oral, rectal
3.4
8.2
30
93
F10.25
ICD-10 Finland
Alcohol dependence continuous use
4.9
8.2
18
38
L02
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle
3.9
8.2
24
64
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
8.3
8.1
17
21
I10
ICD-10 Finland
Essential (primary) hypertension
1.8
8.1
315
2481
F11.29
ICD-10 Finland
Addiction caused by opiates UNS
34.0
8.1
10
*
M45
ICD-10 Finland
Ankylosing spondylitis
34.0
8.1
10
*
R60.9
ICD-10 Finland
Oedema, unspecified
3.3
8.1
31
99
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.7
8.1
43
166
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.1
8.1
34
115
SPAT1212
SPAT
Extensive examination of musculoskeletal system
2.9
8.1
39
143
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
4.0
8.1
23
60
V03AE02
ATC
sevelamer; oral
22.5
8.0
11
5
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.0
8.0
37
132
U14
ICPC
Kidney symptom/complaint
7.4
8.0
18
25
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.1
8.0
87
462
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.4
8.0
20
47
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
8.0
133
819
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
6.8
8.0
19
29
M02AA07
ATC
piroxicam; topical
1.8
8.0
161
1052
M03BC51
ATC
orphenadrine, combinations; systemic
1.9
8.0
110
637
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.3
7.9
30
95
Z72.0
ICD-10 Finland
Tobacco use
4.8
7.9
18
39
ZXE40
NOMESCO Finland
More than seven and less than nine hours
4.8
7.9
18
39
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
3.6
7.9
26
75
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.4
7.9
29
90
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.5
7.9
27
80
M01AH02
ATC
rofecoxib; oral
2.4
7.9
58
263
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
3.2
7.9
31
101
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
3.3
7.8
30
96
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.0
7.8
103
587
T89
ICPC
Diabetes insulin dependent
3.4
7.8
28
86
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.5
7.8
27
81
P01AB01
ATC
metronidazole; oral, rectal
1.8
7.8
164
1084
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.0
7.7
94
520
C09AA02
ATC
enalapril; systemic
1.9
7.7
114
674
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.8
7.7
133
827
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.6
7.7
46
189
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
8.2
7.6
16
20
R02
ICPC
Shortness of breath/dyspnoea
2.2
7.6
66
320
Z71.8
ICD-10 Finland
Other specified counselling
1.8
7.6
132
821
WX702
NOMESCO Finland
Supraglottic ventilation device
3.1
7.5
32
109
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.4
7.5
27
83
M02AA10
ATC
ketoprofen; topical
2.1
7.5
72
365
A41.4
ICD-10 Finland
Sepsis due to anaerobes
81.3
7.4
8
*
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
81.3
7.4
8
*
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.4
7.4
54
243
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
4.1
7.4
20
50
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.7
7.4
39
150
Z2221
NOMESCO Finland
Medical doctor
1.8
7.3
131
822
A02BC01
ATC
omeprazole; systemic
1.8
7.3
123
757
A03FA01
ATC
metoclopramide; systemic, rectal
1.9
7.3
102
591
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.0
7.3
32
111
M51.9
ICD-10 Finland
Intervertebral disc disorder, unspecified
+∞
7.3
7
*
NA3DM
NOMESCO Finland
Lumbar spine very extensive MRI examination with 3 Tesla magnet
+∞
7.3
7
*
M60.0
ICD-10 Finland
Infective myositis
+∞
7.3
7
*
SPAT1211
SPAT
Application of soft bandage
2.5
7.3
47
200
C02AC05
ATC
moxonidine; oral
2.9
7.3
35
128
SPAT1260
SPAT
Consultation of another employee
2.0
7.3
85
463
L01BA01
ATC
methotrexate; systemic
4.4
7.3
18
42
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
16.0
7.3
11
7
L13
ICPC
Hip symptom/complaint
2.0
7.2
80
427
N02AJ13
ATC
tramadol and paracetamol; systemic
7.5
7.2
16
22
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.7
7.2
39
152
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.6
7.2
24
70
WX212
NOMESCO Finland
Femoral plexus blockade
6.7
7.2
17
26
F11.25
ICD-10 Finland
Relationship caused by opiates continuously used
20.4
7.2
10
5
L29
ICPC
Musculoskeletal sympt/complt other
2.7
7.1
38
147
XX1XW
NOMESCO Finland
Extensive written report from radiologist
5.8
7.1
19
34
WX720
NOMESCO Finland
Own respiration
3.3
7.1
27
86
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
3.0
7.1
32
113
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
9.0
7.1
14
16
H02AB07
ATC
prednisone; oral
2.2
7.1
65
323
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
3.6
7.1
23
66
SPAT1216
SPAT
Assessment of functional ability
2.0
7.1
81
438
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
7.1
120
740
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
3.4
7.1
25
76
R4190
NOMESCO Finland
Nutritional therapy
3.5
7.1
24
71
WVA20
NOMESCO Finland
Medicine administration
4.0
7.0
20
52
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
7.0
66
331
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
4.5
7.0
17
39
P15
ICPC
Chronic alcohol abuse
3.8
7.0
21
57
J01CA04
ATC
amoxicillin; systemic
1.8
7.0
360
3006
N05CD07
ATC
temazepam; oral
2.2
7.0
65
325
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.7
7.0
37
143
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
7.7
6.9
15
20
A07AA09
ATC
vancomycin; oral
7.7
6.9
15
20
WX202
NOMESCO Finland
Supraclavicular plexus blockade
7.7
6.9
15
20
D02AE01
ATC
carbamide; topical
2.7
6.9
36
138
WVA20, ,
SPAT
4.2
6.9
18
44
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
8.4
6.9
14
17
M01AH05
ATC
etoricoxib; oral
1.7
6.9
253
1928
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.6
6.8
22
63
R35
ICD-10 Finland
Polyuria
2.6
6.8
38
151
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.4
6.8
24
73
F19.30
ICD-10 Finland
Withdrawal symptoms caused by several drugs in combination and by other psychoactive substances uncomplicated
40.6
6.8
8
*
S21
ICPC
Skin texture symptom/complaint
2.1
6.8
68
350
B01AF02
ATC
apixaban; oral
2.1
6.8
73
386
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.8
6.7
33
122
M01AC06
ATC
meloxicam; systemic, rectal
1.7
6.7
152
1018
A40.0
ICD-10 Finland
Sepsis due to streptococcus, group A
22.9
6.7
9
*
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
22.9
6.7
9
*
M10.9
ICD-10 Finland
Gout, unspecified
2.4
6.7
46
202
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.7
6.7
21
59
SAA03
NOMESCO Finland
Extended examination of mouth
1.7
6.7
161
1097
Z3229
NOMESCO Finland
Other healthcare associate professional
2.3
6.7
51
235
QD9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in lower extremities, unspecified
12.5
6.6
11
9
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.4
6.6
45
197
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
10.2
6.6
12
12
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
10.2
6.6
12
12
WX204
NOMESCO Finland
Axillary plexus blockaced
3.8
6.5
20
55
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.5
6.5
43
185
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.8
6.5
124
789
J02AC01
ATC
fluconazole; systemic
1.8
6.5
131
847
M01AB51
ATC
indometacin, combinations; oral, rectal
5.5
6.5
18
34
E87.5
ICD-10 Finland
Hyperkalaemia
5.5
6.5
18
34
ZZA00
NOMESCO Finland
Split skin graft
3.6
6.5
21
60
205
Kela drug reimbursment
Chronic hypertension
1.7
6.5
147
983
L08
ICPC
Shoulder symptom/complaint
1.9
6.5
92
535
G83.4
ICD-10 Finland
Cauda equina syndrome
70.8
6.4
7
*
A10AE05
ATC
insulin detemir; parenteral
2.6
6.4
36
143
R52.9
ICD-10 Finland
Pain, unspecified
2.5
6.4
42
180
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
6.4
87
498
M01AE01
ATC
ibuprofen; systemic, rectal
1.9
6.4
399
3468
S01.0
ICD-10 Finland
Open wound of scalp
2.3
6.4
47
213
L15
ICPC
Knee symptom/complaint
1.8
6.4
98
585
K92.1
ICD-10 Finland
Melaena
2.7
6.4
34
132
207
Kela drug reimbursment
Chronic arrhythmias
1.9
6.4
93
546
L03.9
ICD-10 Finland
Cellulitis, unspecified
6.1
6.4
16
27
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
6.1
6.4
16
27
A10AC01
ATC
insulin (human); parenteral
2.3
6.3
48
220
NK4AT
NOMESCO Finland
Puncture of joint with ultrasound guidance not elsewher classified
11.2
6.3
11
10
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
9.4
6.3
12
13
M01AH03
ATC
valdecoxib; oral
3.0
6.3
28
98
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
3.9
6.3
18
47
EB1AA, ,
SPAT
2.8
6.3
32
121
N02AA03
ATC
hydromorphone; systemic, rectal
18.3
6.3
9
5
TPX15
NOMESCO Finland
Removal of vascular injection port
18.3
6.3
9
5
IAB10
NOMESCO Finland
Psychiatric consultation concerning substance abuse
18.3
6.3
9
5
QD6S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in foot
18.3
6.3
9
5
A02BC03
ATC
lansoprazole; oral
1.7
6.3
127
822
U04
ICPC
Incontinence urine
2.9
6.3
29
104
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
2.9
6.3
29
104
H02AB04
ATC
methylprednisolone; systemic
2.0
6.3
67
353
NAG65
NOMESCO Finland
Anterior and posterior fusion of lumbar spine
+∞
6.3
6
*
G58.0
ICD-10 Finland
Intercostal neuropathy
+∞
6.3
6
*
72880
ICD-8 Finland
Vertebrogenic pain syndrome, Radicula syndrome of lower limbs
+∞
6.3
6
*
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
6.2
133
873
F19.25
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances continuously used
27.1
6.2
8
*
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.3
6.2
47
215
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.8
6.2
108
668
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.1
6.2
59
297
V49.9
ICD-10 Finland
Car occupant [any] injured in unspecified traffic accident
3.4
6.2
22
67
L09
ICPC
Arm symptom/complaint
3.4
6.2
22
67
L04AA06
ATC
mycophenolic acid; systemic
5.5
6.2
17
32
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
6.4
6.2
15
24
D05AX52
ATC
calcipotriol, combinations; topical
2.9
6.2
29
105
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
7.8
6.2
13
17
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
7.8
6.2
13
17
R5599
NOMESCO Finland
Other rehabilitation service
4.2
6.1
16
39
N03AG01
ATC
valproic acid; systemic, rectal
2.9
6.1
28
100
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.8
6.1
99
600
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
8.8
6.1
12
14
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.3
6.1
44
198
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.3
6.1
44
198
XKD00
NOMESCO Finland
Uroflowmetry
1.8
6.1
102
625
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
10.2
6.1
11
11
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
3.1
6.0
25
84
F10.20
ICD-10 Finland
Alcohol dependence currently independent
5.7
6.0
16
29

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
347
1149
8.25
109.95
13.0
4.2
—
—
—
0
0
211
555
5.99
80.97
3.5
1.9
—
—
—
0
0
352
1667
5.14
60.68
15.4
5.8
0.63
0.66
%
0.49
343
1573
357
1721
5.17
59.80
15.6
5.8
2.92
2.89
%
0.10
346
1631
358
1730
5.18
59.76
16.1
6.0
9.04
9.00
%
0.09
347
1636
358
1732
5.17
59.62
15.2
5.7
60.88
57.70
%
5.37
347
1650
366
1805
5.30
59.33
14.8
5.6
0.04
0.04
e9/l
0.05
330
1570
365
1801
5.26
59.00
14.8
5.6
0.65
0.60
e9/l
3.04
327
1556
369
1838
5.33
58.87
14.7
5.7
1.67
1.93
e9/l
2.01
334
1630
359
1768
5.06
57.64
15.9
5.9
23.90
26.86
%
5.38
348
1679
348
1689
4.83
56.56
14.5
6.1
—
—
—
0
0
367
1859
5.11
56.20
15.4
5.9
0.20
0.19
e9/l
0.65
335
1634
178
557
4.49
52.14
4.3
2.5
18.39
23.13
%
3.90
156
476
384
2102
5.10
50.73
18.7
9.5
4.48
4.11
e9/l
2.49
349
1847
178
575
4.33
49.65
4.3
2.4
2.09
2.25
g/l
2.76
167
529
137
363
4.88
49.38
7.4
3.9
5.81
5.79
kpa
0.06
132
347
90
164
6.52
49.19
2.2
2.1
1.42
2.99
ug/l
0.41
80
145
331
1655
4.21
48.90
11.0
5.0
32.23
35.05
g/l
11.47
320
1541
185
626
4.18
48.22
4.5
2.4
10.15
13.00
umol/l
5.56
178
581
137
372
4.75
47.76
15.4
7.8
13.21
10.38
mmol/l
3.53
131
349
169
542
4.27
47.32
11.9
6.2
1.12
1.03
mmol/l
3.45
158
502
134
360
4.77
47.31
8.3
3.9
1.53
2.14
mmol/l
0.76
118
283
365
1987
4.47
46.92
11.1
6.8
11.24
12.45
umol/l
0.94
358
1891
332
1698
4.08
46.61
12.1
6.4
1.20
1.21
mmol/l
0.86
314
1548
348
1858
4.16
45.37
16.0
7.2
1.20
1.21
mmol/l
0.81
305
1561
148
451
4.30
44.07
2.4
1.6
—
—
—
0
0
124
330
4.72
44.05
8.5
8.4
1.33
1.42
mmol/l
0.39
118
324
230
962
3.67
42.99
3.4
2.1
3.10
3.11
mg/l
0.03
202
821
182
658
3.84
42.34
5.1
3.5
0.81
0.82
mmol/l
0.39
172
627
239
1058
3.50
40.25
4.1
2.9
—
—
—
0
0
344
1927
3.76
39.29
24.4
16.0
1.38
1.34
inr
0.30
89
586
89
198
5.29
38.92
1.9
2.1
1.67
1.55
g/l
0.50
82
177
105
270
4.70
38.60
2.0
2.4
—
—
—
0
0
115
330
4.27
36.55
2.8
2.9
64.38
66.40
g/l
1.64
106
305
372
2257
3.86
36.08
9.4
5.0
6.91
6.88
mmol/l
0.11
364
2130
134
434
3.89
35.93
2.6
1.6
—
—
—
0
0
113
325
4.24
35.75
14.2
9.9
—
—
—
0
0
137
455
3.81
35.36
9.8
8.4
5.20
5.09
kpa
0.58
127
447
137
455
3.81
35.36
9.8
8.3
11.88
12.05
kpa
0.16
126
447
409
2661
4.59
35.34
8.4
3.7
25.23
13.16
mm/h
18.58
398
2408
102
274
4.46
35.29
5.5
4.1
135.88
91.39
ng/l
1.59
94
238
128
417
3.82
33.85
9.8
8.8
95.68
95.52
%
0.14
121
412
280
1475
3.15
33.42
4.6
2.6
201.53
164.82
ug/l
0.98
256
1344
135
461
3.68
33.24
9.9
8.3
1.04
1.37
mmol/l
0.38
111
378
232
1109
3.11
32.70
7.5
4.2
7.40
7.40
ph
0.19
38
223
232
1114
3.09
32.36
2.7
2.1
396.12
326.12
u/l
0.12
216
1041
165
654
3.32
31.95
2.6
2.0
30.96
29.74
s
1.75
160
636
243
1210
3.04
31.56
6.3
3.3
37.63
35.30
u/l
0.28
233
1159
141
512
3.48
31.39
10.5
7.7
104.35
104.34
mmol/l
0.01
141
512
302
1702
3.08
31.22
4.3
2.6
—
—
—
0
0
114
362
3.82
31.09
3.0
2.8
69.46
67.91
e9/l
0.17
79
274
50
80
6.86
30.59
1.9
1.5
50565.79
24236.42
e6/l
0.40
33
57
116
377
3.74
30.53
3.1
2.2
0.19
0.20
g/l
0.46
104
349
415
2865
4.27
29.68
21.8
7.7
101.14
79.28
u/l
8.40
405
2681
236
1187
2.94
29.61
5.7
3.1
36.83
128.11
e6/l
1.00
195
923
219
1062
2.95
29.34
5.6
3.0
0.59
0.50
e6/l
0.26
181
812
174
744
3.10
29.24
2.1
1.7
1229.96
1133.00
nmol/l
0.62
137
562
38
47
8.69
29.00
1.9
1.3
—
—
—
0
0
260
1389
2.90
28.96
3.4
2.1
75.01
76.51
nmol/l
0.37
237
1216
41
56
7.91
28.85
1.7
1.5
—
—
—
0
0
380
2504
3.46
28.72
7.2
3.9
—
—
—
0
0
133
490
3.37
28.67
3.0
2.6
1.89
1.74
%
1.04
119
441
234
1204
2.84
27.65
5.0
2.4
—
—
—
0
0
208
1011
2.86
27.32
5.5
3.0
—
—
—
0
0
63
144
4.88
26.34
2.2
2.2
10.66
10.57
g/l
0.05
57
126
79
217
4.16
26.16
12.0
11.0
—
—
—
0
0
118
427
3.34
25.95
5.0
2.8
9.55
9.77
umol/l
0.04
104
382
220
1125
2.76
25.89
3.8
2.4
49.45
62.58
u/l
2.29
210
1046
246
1334
2.73
25.73
6.8
3.5
74.94
163.10
e6/l
0.87
200
974
191
915
2.80
25.43
4.4
2.4
—
—
—
0
0
108
375
3.42
25.33
2.4
1.5
—
—
—
0
0
59
132
4.95
25.28
1.9
3.5
39.27
36.21
mg/l
0.19
47
113
174
798
2.85
25.13
4.8
2.8
532.22
567.62
mosm/kgh2o
1.65
157
688
176
813
2.84
25.06
4.4
2.5
5.33
4.17
e6/l
0.83
163
736
101
344
3.45
24.36
2.8
2.2
28.27
167.55
u/l
0.51
83
296
58
132
4.86
24.33
1.9
3.5
55.44
116.54
mg/l
0.71
46
110
249
1392
2.64
24.01
4.6
3.2
5.58
5.84
ph
—
6
100
143
608
2.92
23.57
4.4
2.9
2.09
1.89
e6/l
0.13
83
347
199
1006
2.67
23.45
4.3
2.8
4143.96
6736.58
umol/l
0.39
178
881
110
420
3.10
21.81
1.5
1.3
350.48
321.95
titre
0.08
21
82
183
916
2.61
21.67
16.2
6.7
—
—
—
0
0
142
631
2.77
21.28
4.1
2.7
1.81
1.12
e6/l
0.78
86
366
281
1728
2.51
21.28
7.0
4.7
0.00
0.00
estimate
-0.00
52
335
100
366
3.19
21.27
2.3
1.6
—
—
—
0
0
113
446
3.00
21.08
1.7
1.4
—
—
—
0
0
264
1583
2.48
21.05
2.7
2.0
93.26
94.04
pmol/l
0.10
155
830
279
1721
2.48
20.82
5.0
3.4
0.00
0.00
estimate
-0.00
54
353
281
1745
2.47
20.58
5.0
3.4
0.00
0.01
estimate
0.50
49
312
53
130
4.46
20.20
1.4
2.1
32.48
37.27
g/l
4.39
47
113
217
1216
2.43
19.77
3.9
3.1
2830.61
1578.82
ng/l
1.57
185
1069
157
760
2.58
19.61
5.0
3.6
526.68
422.66
ng/l
0.16
133
629
44
96
4.94
19.32
2.0
4.0
—
—
—
0
0
84
295
3.24
19.02
2.0
2.6
12.49
10.86
g/l
1.72
79
270
33
56
6.25
18.95
4.6
2.3
—
—
—
0
0
147
704
2.57
18.64
1.9
1.7
1.91
1.49
mg/l
0.49
129
556
266
1666
2.33
18.35
26.3
9.6
0.00
0.00
e9/l
0.49
213
1370
29
48
6.37
17.04
6.2
3.9
—
—
—
0
0
175
951
2.32
16.45
2.2
1.5
17.62
20.57
nmol/l
2.30
158
794
35
72
5.16
16.41
5.9
2.6
—
—
—
0
0
69
235
3.26
16.34
1.6
1.5
—
—
—
0
0
35
75
4.95
15.66
5.9
2.6
—
—
—
0
0
24
36
6.96
15.44
3.8
3.0
—
—
—
0
0
40
97
4.41
15.42
1.2
1.7
—
—
—
0
0
447
3695
3.97
15.31
55.0
14.4
34.05
27.93
mg/l
4.44
432
2939
73
267
3.04
15.30
5.8
5.0
—
—
—
0
0
147
762
2.34
15.25
4.2
3.4
—
—
—
0
0
35
77
4.82
15.19
5.9
2.5
—
—
—
0
0
24
37
6.77
15.06
1.5
1.4
81.86
68.52
%
0.95
14
29
37
86
4.58
15.03
3.7
2.7
—
—
—
0
0
27
48
5.90
14.77
2.1
1.4
58.95
52.05
mmol/l
0.35
20
41
34
76
4.74
14.47
6.0
2.1
—
—
—
0
0
34
77
4.68
14.25
6.1
2.5
—
—
—
0
0
71
269
2.92
13.94
4.7
4.2
0.49
0.66
%
0.55
35
101
75
296
2.82
13.65
5.7
4.3
0.76
0.87
%
0.19
37
116
29
61
4.99
13.24
1.8
1.5
122.60
96.90
u/ml
—
5
10
326
2395
2.12
13.12
6.6
3.0
86.46
58.61
u/l
3.14
312
2205
201
1252
2.04
12.64
5.4
3.7
2.32
2.35
mmol/l
2.13
185
1106
66
256
2.83
12.37
5.8
3.5
7.39
7.40
ph
—
9
31
70
283
2.72
12.12
5.6
4.4
0.13
0.15
%
0.09
32
103
67
267
2.75
11.92
5.2
4.4
0.07
1.19
%
0.58
29
88
343
2614
2.09
11.89
3.9
3.4
14.93
14.95
pmol/l
0.05
307
2312
29
69
4.41
11.43
2.0
1.5
—
—
—
0
0
18
13
14.33
11.05
1.9
1.5
—
—
—
0
0
26
60
4.52
10.64
1.8
1.5
32.44
30.57
g/l
0.26
21
55
116
624
2.13
10.53
1.5
1.5
3.31
2.70
g/l
1.87
90
389
78
356
2.42
10.48
2.3
2.3
7.33
8.75
ug/l
0.28
68
315
40
129
3.29
10.28
7.3
5.8
1.38
1.24
mmol/l
0.39
34
119
222
1512
1.87
10.11
5.7
3.6
50.42
72.68
ng/l
0.46
192
1135
30
81
3.88
10.03
1.2
1.2
—
—
—
0
0
28
72
4.07
9.99
3.2
2.7
63.39
65.30
%
0.14
28
72
33
96
3.62
9.93
1.2
1.2
—
—
—
0
0
18
17
10.95
9.86
1.5
1.0
470.06
303.29
iu/ml
0.40
18
17
27
70
4.03
9.53
1.2
1.2
263.12
348.34
u/ml
0.62
17
35
26
66
4.11
9.44
1.0
1.0
—
—
—
0
0
93
478
2.17
9.40
1.4
1.2
43.14
38.11
iu/ml
0.15
35
150
20
41
5.05
9.39
1.8
1.4
—
—
—
0
0
88
448
2.18
9.10
1.4
1.2
23.04
12.35
u/ml
0.32
22
169
22
52
4.39
8.75
2.9
2.5
2.08
1.42
g/24h
—
10
25
126
745
1.94
8.63
5.2
3.8
1.01
1.02
kg/l
0.61
20
109
49
196
2.67
8.62
6.1
3.6
—
—
—
0
0
21
50
4.35
8.28
1.9
1.4
2574.75
1355.03
e6/l
0.40
12
35
25
69
3.77
8.12
1.3
1.1
—
—
—
0
0
23
60
3.98
8.06
1.1
1.1
—
—
—
0
0
440
3893
2.53
7.82
39.9
13.8
—
—
—
0
0
392
3327
1.96
7.64
5.0
4.1
2.08
2.03
mu/l
0.24
366
2954
27
83
3.39
7.50
4.2
4.0
—
—
—
0
0
20
50
4.13
7.42
1.8
1.4
—
—
—
0
0
44
180
2.59
7.41
1.4
1.2
—
—
—
0
0
19
46
4.26
7.34
1.9
1.3
152385.45
23814.15
e6/l
0.40
11
27
26
80
3.38
7.21
3.6
2.5
15.40
16.03
%
0.28
13
41
90
502
1.98
7.21
1.3
1.3
—
—
—
0
0
25
75
3.46
7.20
3.7
2.9
—
—
—
0
0
28
92
3.17
7.01
4.3
4.3
3.55
2.47
mmol/l
0.94
21
58
16
25
6.58
6.69
1.6
2.1
—
—
—
0
0
447
4036
2.52
6.65
27.8
10.2
27.73
27.03
u/l
0.29
441
3860
12
12
10.22
6.56
3.7
2.9
—
—
—
0
0
12
12
10.22
6.56
1.6
1.5
—
—
—
0
0
82
458
1.95
6.51
4.6
4.6
14.31
33.34
ug/l
0.49
74
383
18
47
3.94
6.31
1.6
2.2
—
—
—
0
0
182
1304
1.64
6.10
5.3
3.3
6.34
7.96
mmol/l
5.96
155
1073
17
45
3.88
5.86
1.2
1.1
—
—
—
0
0
24
81
3.07
5.77
2.8
2.4
123.31
130.41
g/l
0.50
16
65
16
31
5.30
5.75
1.8
1.3
16011.67
358809.05
e6/l
—
9
22
129
859
1.69
5.68
2.2
1.8
454.10
27207358.26
pmol/l
1.00
112
691
331
2767
1.63
5.68
5.3
3.9
—
—
—
0
0
20
61
3.38
5.64
2.5
2.3
—
—
—
0
0
84
496
1.84
5.61
1.4
1.2
—
—
—
0
0
19
57
3.43
5.50
1.7
2.2
—
—
—
0
0
30
118
2.64
5.49
5.3
3.2
—
—
—
0
0
18
54
3.42
5.21
1.4
1.7
—
—
—
0
0
12
19
6.45
5.11
1.6
1.2
—
—
—
0
0
108
704
1.69
5.10
4.3
3.3
2.46
2.45
mmol/l
0.20
90
622
19
60
3.26
5.09
7.8
3.0
—
—
—
0
0
140
979
1.61
5.01
5.3
3.1
—
—
—
0
0
22
78
2.91
4.88
1.1
1.1
—
—
—
0
0
14
29
4.94
4.84
1.8
1.3
19.94
29.10
%
—
9
21
452
4196
2.28
4.65
68.5
21.3
37.33
40.32
%
19.74
418
3899
43
215
2.10
4.63
6.9
2.7
4.21
4.05
e9/l
0.14
33
170
34
157
2.25
4.45
5.8
3.4
0.26
0.21
g/l
0.45
25
68
39
193
2.11
4.32
3.3
2.8
—
—
—
0
0
68
408
1.78
4.29
1.7
1.3
—
—
—
0
0
187
1443
1.48
4.14
2.6
2.2
—
—
—
0
0
8
10
8.11
4.07
4.7
6.8
—
—
—
0
0
13
31
4.28
4.04
1.2
1.1
—
—
—
0
0
7
7
10.12
4.02
18.4
7.7
4.81
6.33
mmol/l
—
7
7
9
14
6.53
4.00
1.9
2.6
—
—
—
0
0
10
18
5.65
3.99
1.0
1.0
—
—
—
0
0
13
33
4.02
3.82
1.2
1.3
—
—
—
0
0
32
156
2.13
3.70
6.8
5.0
—
—
—
0
0
8
12
6.76
3.68
1.4
1.3
—
—
—
0
0
20
79
2.60
3.68
1.8
1.8
—
—
—
0
0
5
196
0.25
3.62
1.4
1.4
—
—
—
0
0
35
179
2.03
3.59
2.5
2.6
—
—
—
0
0
63
390
1.71
3.57
1.7
1.4
—
—
—
0
0
10
21
4.84
3.57
1.3
1.3
—
—
—
0
0
12
31
3.94
3.51
1.8
1.8
—
—
—
0
0
162
1248
1.45
3.50
5.3
3.4
1353.48
201.01
mg/l
1.18
124
842
101
1383
0.66
3.42
3.8
3.0
—
—
—
0
0
171
1337
1.43
3.40
5.9
4.0
28.21
8.94
mg/mmol
1.74
122
873
13
38
3.49
3.33
1.0
1.2
—
—
—
0
0
13
43
3.08
3.27
4.5
2.6
—
—
—
0
0
19
78
2.49
3.25
1.9
1.2
2.69
49.73
e6/l
0.62
13
62
52
317
1.72
3.13
7.9
3.3
1.23
1.23
mmol/l
0.17
52
270
9
20
4.56
3.12
1.0
1.0
—
—
—
0
0
7
12
5.90
3.03
1.1
1.9
—
—
—
0
0
53
328
1.69
3.02
3.4
2.4
173.72
137.14
ug/g
0.26
46
261
11
31
3.61
3.01
1.2
1.3
—
—
nmol/l
—
0
0
17
69
2.52
2.99
7.5
3.2
59.18
57.74
%
0.22
17
69
5
5
10.09
2.98
7.0
9.0
40.60
29.40
ug/min
—
5
5
135
1032
1.43
2.98
1.8
1.6
1.44
1.35
mmol/l
0.70
114
829
20
88
2.33
2.97
1.5
1.4
189.02
277.60
ug/g
—
7
51
8
17
4.77
2.93
2.4
2.1
—
—
—
0
0
18
76
2.42
2.93
1.3
1.2
4.56
3.80
mmol/l
1.13
18
70
6
9
6.73
2.87
1.3
1.4
—
—
—
0
0
20
90
2.28
2.84
2.1
1.6
177.35
237.61
pmol/l
1.67
20
83
390
3578
1.48
2.83
8.1
6.1
41.93
40.76
mmol/mol
1.35
365
3274
16
65
2.51
2.82
5.1
2.9
4.27
4.37
e9/l
0.08
16
65
10
267
0.36
2.79
1.8
1.4
—
—
—
0
0
47
288
1.70
2.79
6.3
3.2
—
—
—
0
0
5
6
8.40
2.75
1.2
1.5
—
—
—
0
0
132
1021
1.40
2.70
1.4
1.3
—
—
—
0
0
42
253
1.72
2.65
1.3
1.4
—
—
—
0
0
14
55
2.59
2.64
1.4
2.1
30.64
32.98
pg
0.93
14
55
17
74
2.34
2.61
1.8
1.2
—
—
—
0
0
7
15
4.72
2.60
3.4
1.6
117.29
61.33
ug/l
—
7
15
16
68
2.40
2.58
2.4
1.5
—
—
—
0
0
122
939
1.40
2.56
6.3
3.6
0.00
0.01
estimate
0.69
42
317
25
131
1.96
2.45
2.4
1.9
—
—
—
0
0
38
228
1.72
2.45
4.8
2.5
0.30
0.24
e6/l
0.23
38
221
16
70
2.33
2.44
1.8
1.7
—
—
—
0
0
6
12
5.05
2.41
1.0
1.1
—
—
—
0
0
33
191
1.78
2.40
1.4
1.3
—
78.40
—
0
11
5
8
6.30
2.37
74.4
5.4
—
—
—
0
0
10
33
3.07
2.37
1.2
1.4
—
—
—
0
0
10
33
3.07
2.37
4.0
2.7
—
—
—
0
0
25
133
1.93
2.36
1.9
1.5
—
—
—
0
0
24
126
1.95
2.35
2.2
1.7
46.92
40.48
nmol/l
0.80
24
121
89
657
1.44
2.35
1.3
1.2
1.05
1.03
u/ml
0.02
24
174
31
178
1.79
2.32
5.2
3.8
—
—
—
0
0
19
92
2.11
2.30
1.4
1.2
—
—
—
0
0
6
13
4.66
2.28
1.2
1.2
—
—
—
0
0
6
13
4.66
2.28
1.0
1.0
—
—
—
0
0
35
210
1.72
2.27
2.5
2.4
—
20.45
—
0
10
28
158
1.82
2.22
1.3
1.3
242.02
188.30
u/ml
0.26
28
147
7
19
3.72
2.16
10.4
2.2
—
—
—
0
0
6
14
4.33
2.15
6.0
2.2
—
—
—
0
0
11
43
2.59
2.09
1.2
1.1
—
—
—
0
0
55
378
1.51
2.08
10.8
4.4
—
—
—
0
0
14
63
2.26
2.02
3.2
2.5
—
—
—
0
0
6
16
3.78
1.94
1.7
1.1
—
—
—
0
0
6
16
3.78
1.94
1.3
1.2
16.33
12.20
g/l
—
6
9
33
205
1.65
1.91
1.2
1.2
—
—
—
0
0
21
115
1.86
1.86
3.4
2.7
48.67
57.27
u/ml
0.09
21
108
396
3725
1.36
1.79
5.5
4.7
6.29
6.10
mmol/l
1.30
356
3334
9
36
2.53
1.74
1.1
1.2
—
—
—
0
0
10
40
2.53
1.67
4.0
3.3
53.80
51.00
%
—
10
34
7
25
2.83
1.65
1.1
1.1
—
—
—
0
0
13
63
2.09
1.61
3.2
2.7
—
—
—
0
0
13
63
2.09
1.61
2.2
1.3
—
—
—
0
0
33
216
1.57
1.59
1.2
1.2
—
—
—
0
0
6
20
3.02
1.58
1.3
1.1
124.17
131.80
nmol/l
—
6
20
7
28
2.52
1.45
2.6
3.7
—
—
—
0
0
5
16
3.15
1.44
1.8
1.4
69.40
89.18
%
—
5
11
7
29
2.43
1.39
1.1
1.1
—
—
—
0
0
26
168
1.58
1.34
1.2
1.2
—
—
—
0
0
11
54
2.06
1.33
2.9
2.6
—
—
—
0
0
6
24
2.52
1.30
3.3
4.3
—
—
—
0
0
8
34
2.38
1.29
1.1
1.1
—
—
—
0
0
8
36
2.24
1.24
2.5
1.1
—
—
—
0
0
141
1214
1.23
1.24
7.2
3.9
—
—
—
0
0
10
49
2.06
1.22
4.1
3.6
—
—
—
0
0
8
37
2.18
1.22
1.4
1.6
10.82
10.79
%
—
8
37
5
19
2.65
1.22
1.2
2.1
978.60
2085.37
u/ml
—
5
19
5
19
2.65
1.22
1.8
1.3
—
—
—
0
0
44
325
1.39
1.21
7.8
3.6
—
—
—
0
0
6
26
2.32
1.19
1.7
1.3
—
—
—
0
0
10
50
2.02
1.17
1.1
1.2
—
—
—
0
0
7
30
2.35
1.12
1.7
1.8
33.01
30.27
%
—
7
30
5
21
2.40
1.09
1.0
1.0
—
—
—
0
0
8
41
1.97
1.09
1.0
1.0
—
—
—
0
0
8
41
1.97
1.09
1.0
1.0
—
—
—
0
0
220
1998
1.19
1.08
5.3
4.9
1.97
2.66
ug/l
1.78
191
1759
6
27
2.24
0.93
1.0
1.1
—
—
—
0
0
6
27
2.24
0.93
2.2
2.1
608.00
448.48
e6/l
—
6
27
5
102
0.48
0.90
1.2
1.7
—
—
—
0
0
18
119
1.53
0.89
6.6
4.3
—
—
—
0
0
8
42
1.92
0.89
3.1
1.2
—
—
—
0
0
401
3877
1.21
0.80
5.8
5.0
2.42
2.65
mmol/l
5.60
376
3515
0
28
0.00
0.76
0.0
6.5
—
21.26
—
0
9
378
3645
1.17
0.73
4.9
4.0
1.33
1.30
mmol/l
0.37
348
3279
5
25
2.01
0.73
1.0
1.8
—
—
—
0
0
17
119
1.44
0.68
1.6
1.6
—
—
—
0
0
7
43
1.64
0.67
2.9
2.3
—
—
—
0
0
7
43
1.64
0.67
1.4
1.2
—
—
—
0
0
10
62
1.63
0.65
4.1
2.6
17.50
22.44
u/ml
—
10
62
43
351
1.25
0.65
1.5
1.5
—
—
—
0
0
44
362
1.24
0.63
2.9
2.1
13.31
13.19
nmol/l
0.03
38
334
29
230
1.28
0.57
4.7
2.9
—
—
—
0
0
387
3761
1.15
0.56
5.3
4.4
1.35
1.40
mmol/l
1.67
361
3409
6
38
1.59
0.54
1.0
1.1
—
—
—
0
0
21
161
1.32
0.52
1.2
1.2
232.20
152.76
iu/ml
—
5
69
6
40
1.51
0.51
1.2
1.2
—
—
—
0
0
389
3792
1.14
0.49
5.5
4.5
4.24
4.49
mmol/l
4.94
367
3469
7
107
0.65
0.49
1.3
1.5
—
—
—
0
0
5
31
1.62
0.43
1.2
1.5
—
—
—
0
0
5
33
1.52
0.41
1.4
3.8
7.16
7.49
mmol/l
—
5
22
0
17
0.00
0.40
0.0
1.5
—
—
—
0
0
0
19
0.00
0.39
0.0
8.3
—
—
—
0
0
6
46
1.31
0.33
1.5
1.2
—
—
—
0
0
19
220
0.86
0.22
1.3
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
14
119
1.18
0.18
3.3
2.3
312.39
94.29
ug/min
—
8
70
122
1177
1.05
0.15
3.1
3.0
0.72
0.81
ug/l
0.49
84
809
6
57
1.05
0.08
1.5
1.3
—
—
—
0
0
32
337
0.95
0.07
1.4
1.4
—
—
—
0
0
9
102
0.88
0.06
1.1
1.1
—
—
—
0
0
14
133
1.05
0.01
1.1
1.2
—
—
—
0
0
11
115
0.96
0.00
7.2
8.0
—
—
—
0
0
14
143
0.98
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
-0.00
1.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_DISCINFECTION and mortality.

Females

Parameter HR [95% CI] p-value
M13_DISCINFECTION 2.197 [1.72, 2.81] < 0.001
Birth year 0.991 [0.98, 1.0] 0.048

During the follow-up period (1.1.1998 — 31.12.2019), 208 out of 774 females with M13_DISCINFECTION died.

Males

Parameter HR [95% CI] p-value
M13_DISCINFECTION 2.163 [1.73, 2.7] < 0.001
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 430 out of 1413 males with M13_DISCINFECTION died.

Mortality risk

Mortality risk for people of age

years, who have M13_DISCINFECTION.

N-year risk Females Males
1 0.152% 0.427%
5 1.139% 2.451%
10 2.617% 5.546%
15 5.3% 10.663%
20 9.26% 18.144%

Relationships between endpoints

Index endpoint: M13_DISCINFECTION – Infection of intervertebral disc (pyogenic)

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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