No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1646 |
4. Check minimum number of eventsNone |
1646 |
5. Include endpointsNone |
1646 |
6. Filter based on genotype QC (FinnGen only) |
1646 |
Control definitions (FinnGen only)
- Control exclude
- H7_VISUALDISTBLIND
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H53
- Name in latin
- Amblyopia ex anopsia
Similar endpoints
↥List of similar endpoints to
Amblyopia ex anopsia
based on the number of shared cases.
Similar with more cases:
- Visual disturbances
- Visual disturbances and blindness
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 31190 | 15645 | 15478 |
| Only index persons | 23884 | 12205 | 11679 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.44 | 0.45 | 0.43 |
| Only index persons | 0.45 | 0.45 | 0.45 |
| Median age at first event (years) | |||
| Whole population | 6.33 | 6.37 | 6.15 |
| Only index persons | 6.77 | 6.98 | 6.55 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1646 | 1023 | 623 |
| Unadjusted period prevalence (%) | 0.32 | 0.35 | 0.27 |
| Median age at first event (years) | 17.40 | 12.90 | 24.79 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1463
- Matched controls
- 14631
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H53.0
ICD-10 Finland
Amblyopia ex anopsia
9455.5
323.0
1169
6
37720
ICD-8 Finland
Other diseases of retina and optic nerve, Amblyopia
+∞
236.0
220
*
H50.0
ICD-10 Finland
Convergent concomitant strabismus
39.3
119.6
152
43
H52.0
ICD-10 Finland
Hypermetropia
16.5
115.3
191
132
3680A
ICD-9 Finland
Visual disturbances, Amblyopia ex anopsia
+∞
107.6
102
*
37300
ICD-8 Finland
Strabismus, Concomitans convergens
51.6
91.5
110
23
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
33.8
77.0
101
32
H52.2
ICD-10 Finland
Astigmatism
14.8
75.2
129
95
H50.1
ICD-10 Finland
Divergent concomitant strabismus
31.4
72.7
97
33
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.2
54.6
343
1289
H53.1
ICD-10 Finland
Subjective visual disturbances
10.4
48.3
97
99
H50.30
ICD-10 Finland
Intermittent esotropy
20.4
47.9
72
37
Z96.1
ICD-10 Finland
Presence of intraocular lens
4.0
47.1
205
571
H50.31
ICD-10 Finland
Intermittent exotropia
12.8
46.6
84
69
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
20.6
46.1
69
35
37301
ICD-8 Finland
Strabismus, Concomitans divergens
21.5
40.7
60
29
XCK00
NOMESCO Finland
Perimetry
4.9
38.6
134
297
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.3
34.2
186
614
H53.2
ICD-10 Finland
Diplopia
26.6
32.0
44
17
H53.4
ICD-10 Finland
Visual field defects
36.4
30.7
39
11
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.3
29.8
325
1619
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.1
28.7
415
2337
3780A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONCOMITANS CONVERGENS]
65.3
28.0
32
5
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
102.0
27.7
30
*
H52.1
ICD-10 Finland
Myopia
4.4
26.8
100
238
37001
ICD-8 Finland
Refractive errors, Hypermetropia. Hyperopia
142.6
26.7
28
*
H54.5
ICD-10 Finland
Severe visual impairment, monocular
35.1
24.3
31
9
H25.8
ICD-10 Finland
Other senile cataract
3.1
24.0
141
489
H54.7
ICD-10 Finland
Unspecified visual loss
28.7
23.2
31
11
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.1
22.4
128
435
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.0
21.2
127
447
3503
FHL
Single muscle retroposition
23.8
20.0
28
12
H50.2
ICD-10 Finland
Vertical strabismus
14.2
19.1
32
23
37003
ICD-8 Finland
Refractive errors, Anisometropia
+∞
18.8
18
*
CJB10
NOMESCO Finland
Laser discission of secondary cataract
3.2
18.5
101
333
3781A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS CONCOMITANS DIVERGENS]
171.8
16.5
17
*
XCK10
NOMESCO Finland
Photography of fundus of eye
2.5
16.5
132
550
CEC00
NOMESCO Finland
Recession of extraocular muscle
13.6
16.5
28
21
H53.3
ICD-10 Finland
Other disorders of binocular vision
40.6
16.3
20
5
H53.9
ICD-10 Finland
Visual disturbance, unspecified
6.0
16.1
44
75
3671A
ICD-9 Finland
Disorders of refraction and accommodation, Myopia
161.6
15.5
16
*
H25.1
ICD-10 Finland
Senile nuclear cataract
1.9
15.5
233
1297
H26.4
ICD-10 Finland
After-cataract
2.8
15.5
104
394
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.1
15.2
83
275
3507
FHL
Retroposition and resection
45.5
15.1
18
*
Q12.0
ICD-10 Finland
Congenital cataract
36.4
14.5
18
5
ZXA10
NOMESCO Finland
Bilateral
1.8
14.1
248
1459
H50.52
ICD-10 Finland
Exophoria
5.2
13.8
42
82
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
13.7
13.7
23
17
R51.80
ICD-10 Finland
Headache
1.9
13.7
234
1359
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.4
13.5
120
532
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
3.3
12.8
63
194
XCD10
NOMESCO Finland
Electrophysiological examination of eye
4.3
12.4
45
107
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
12.3
416
2940
SPAT1263
SPAT
Sampling
1.5
12.1
594
4574
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.6
12.1
87
345
H25.0
ICD-10 Finland
Senile incipient cataract
2.9
12.0
71
249
Z31.5
ICD-10 Finland
Genetic counselling
2.6
11.8
89
361
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.1
11.6
138
698
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.1
11.3
134
677
3505
FHL
Single muscle resection
35.3
11.3
14
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
11.2
472
3498
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
25.2
11.1
15
6
H50.51
ICD-10 Finland
Esophoria
10.1
11.0
21
21
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.2
11.0
118
571
H33.0
ICD-10 Finland
Retinal detachment with retinal break
4.1
10.7
41
103
H27.0
ICD-10 Finland
Aphakia
28.2
10.7
14
5
CEC50
NOMESCO Finland
Advancement of extraocular muscle
+∞
10.4
10
*
SPAT1301
SPAT
No procedures
1.5
10.4
434
3196
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.7
9.8
200
1223
WX140
NOMESCO Finland
Parabulbar anesthesy
3.2
9.8
50
160
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
9.8
258
1700
SPAT1262
SPAT
Handing over of treatment supplies
1.7
9.7
197
1202
H47.2
ICD-10 Finland
Optic atrophy
17.6
9.4
14
8
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.0
9.4
115
587
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.7
9.3
226
1457
SPAT1216
SPAT
Assessment of functional ability
1.8
9.1
156
903
H40.0
ICD-10 Finland
Glaucoma suspect
2.3
9.0
81
363
3780B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONVERGENS ALTERNANS]
36.9
9.0
11
*
3781B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS DIVERGENS ALTERNANS]
36.9
9.0
11
*
H50.9
ICD-10 Finland
Strabismus, unspecified
8.0
8.9
19
24
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
8.8
347
2512
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.7
8.7
177
1083
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
20.1
8.5
12
6
H26.02
ICD-10 Finland
Presenil cataract
3.8
8.5
34
91
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.2
8.4
82
383
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
90.5
8.4
9
*
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
6.7
8.4
20
30
37000
ICD-8 Finland
Refractive errors, Astigmatismus
+∞
8.3
8
*
WX110
NOMESCO Finland
Local anesthesy
1.4
8.2
950
8353
CEC30
NOMESCO Finland
Resection of extraocular muscle
14.6
8.2
13
9
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.4
8.1
734
6187
ZXA05
NOMESCO Finland
Left side
1.5
8.0
262
1814
N05BA01
ATC
diazepam; systemic, rectal
1.8
7.9
148
880
XA800
NOMESCO Finland
Neuropsychological investigation
2.2
7.8
74
339
CEW99
NOMESCO Finland
Other operation on extraocular muscle
45.2
7.7
9
*
F95
ICPC
Strabismus
45.2
7.7
9
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.0
7.7
94
481
AA1AD
NOMESCO Finland
CT of head and brain
1.6
7.7
220
1477
ZXA00
NOMESCO Finland
Right side
1.5
7.6
271
1910
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.2
7.6
74
346
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.7
7.6
145
870
K02.1
ICD-10 Finland
Caries of dentine
1.4
7.5
788
6769
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
7.4
185
1199
114
Kela drug reimbursment
Glaucoma
2.1
7.3
81
401
S01ED01
ATC
timolol; ophthalmic
2.9
7.2
42
148
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
6.3
7.2
18
29
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
7.2
673
5654
Q21.10
ICD-10 Finland
Persistent ostium secundum
4.3
7.2
25
59
H03AA01
ATC
levothyroxine sodium; systemic
1.5
7.2
234
1617
H44.2
ICD-10 Finland
Degenerative myopia
20.1
7.1
10
5
37929
ICD-8 Finland
Blindness, one eye, specifically defined
20.1
7.1
10
5
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
6.6
7.1
17
26
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
7.1
226
1556
G91.1
ICD-10 Finland
Obstructive hydrocephalus
8.8
7.0
14
16
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
4.0
7.0
26
66
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
3.2
7.0
34
108
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.8
6.9
41
148
602
Kela drug reimbursment
Children's severe malnutrition
3.5
6.8
29
83
SPAT1153
SPAT
Removal of sutures
1.4
6.8
322
2403
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
9.4
6.8
13
14
CEC20
NOMESCO Finland
Recession and advancement of extraocular muscle
40.2
6.8
8
*
37002
ICD-8 Finland
Refractive errors, Myopia
40.2
6.8
8
*
F82
ICD-10 Finland
Specific developmental disorder of motor function
3.5
6.7
29
84
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
6.7
707
6033
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
4.9
6.7
20
41
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.0
6.7
80
408
N06AB10
ATC
escitalopram; oral
1.5
6.6
250
1785
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
5.9
6.6
17
29
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
3.1
6.6
34
113
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
6.6
161
1038
F83
ICD-10 Finland
Mixed specific developmental disorders
3.0
6.5
35
119
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
6.5
310
2315
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.4
6.5
285
2095
R62.0
ICD-10 Finland
Delayed milestone
2.8
6.5
39
143
TAB00
NOMESCO Finland
Lumbar puncture
2.3
6.4
58
263
Q14.2
ICD-10 Finland
Congenital malformation of optic disc
70.1
6.4
7
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.5
6.4
47
193
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.7
6.4
117
694
C07AA05
ATC
propranolol; systemic
1.5
6.3
215
1501
Z94.0
ICD-10 Finland
Kidney transplant status
4.2
6.3
22
53
N03AG01
ATC
valproic acid; systemic, rectal
2.0
6.3
76
392
SPAT1312
SPAT
General health counselling
1.3
6.3
487
3952
3670A
ICD-9 Finland
Disorders of refraction and accommodation, Hypermetropia
+∞
6.3
6
*
3673A
ICD-9 Finland
Disorders of refraction and accommodation, Anisometropia and aniseikonia
+∞
6.3
6
*
H54.0
ICD-10 Finland
Blindness, binocular
+∞
6.3
6
*
SPAT1310
SPAT
Counselling related to known health issue
1.4
6.2
434
3459
3768
FHL
Eye examination under general anesthesia
26.8
6.2
8
*
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
4.8
6.2
19
40
N03AX16
ATC
pregabalin; oral
1.5
6.2
218
1531
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
6.2
284
2102
S01ED51
ATC
timolol, combinations; ophthalmic
2.0
6.2
70
351
S01FA01
ATC
atropine; ophthalmic
7.7
6.1
13
17
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.0
6.1
76
394
N05BA04
ATC
oxazepam; oral
1.5
6.1
257
1874
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
6.1
258
1881
WX704
NOMESCO Finland
Intubation
1.9
6.1
88
486
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
8.6
6.1
12
14
WX400
NOMESCO Finland
Inhalation anesthesy
2.0
6.0
72
370
N06AB03
ATC
fluoxetine; oral
1.6
6.0
145
930
N06AB06
ATC
sertraline; oral
1.7
6.0
134
842
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
6.0
97
554
G47.3
ICD-10 Finland
Sleep apnoea
1.5
6.0
189
1292
S01EC01
ATC
acetazolamide; systemic
3.5
6.0
26
76
SPAT1053
SPAT
Memory test
1.7
6.0
114
683
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
744
5781
1.52
15.24
9.0
7.4
1.2
1.2
mmol/l
0.26
624
4965
529
3862
1.54
14.21
3.8
3.2
43.8
46.5
ng/l
0.07
328
2341
212
1233
1.83
13.68
5.7
6.2
—
—
—
0
0
1063
9093
1.48
12.39
6.9
6.7
82.5
82.6
u/l
0.02
981
8535
432
3116
1.52
11.89
2.5
2.1
176.0
264.8
u/l
1.53
409
2935
862
7129
1.44
11.69
6.0
4.8
6.6
6.5
mmol/l
0.58
779
6568
666
5291
1.43
11.04
8.9
6.9
1.2
1.2
mmol/l
0.29
605
4837
618
4860
1.43
10.76
5.2
5.2
36.7
36.3
g/l
0.81
564
4514
276
1847
1.59
10.47
1.8
1.7
1225.5
1182.5
nmol/l
0.34
207
1387
470
3544
1.46
10.12
2.6
2.5
56.8
56.8
u/l
0.01
432
3270
1156
10222
1.44
10.04
4.5
3.8
14.8
14.6
pmol/l
1.75
1033
9311
75
344
2.24
9.41
1.5
2.4
508.3
458.5
mg/l
0.29
70
327
367
2679
1.48
9.22
3.6
3.2
1833.2
1243.2
ng/l
1.03
305
2233
153
909
1.75
9.13
6.1
5.0
62.0
74.8
ng/l
2.58
131
821
1175
10499
1.42
9.02
6.0
4.9
38.8
38.7
mmol/mol
0.17
1085
9797
257
1748
1.56
9.01
9.5
7.2
1.2
1.1
mmol/l
0.73
238
1632
1395
12898
1.53
8.79
17.3
13.4
139.5
139.6
mmol/l
0.51
1358
12524
1050
9232
1.38
8.68
4.4
4.0
11.1
10.5
mm/h
0.76
953
8535
1396
12928
1.53
8.53
17.5
13.5
4.0
3.9
mmol/l
2.20
1356
12517
37
126
2.98
8.53
2.1
1.5
—
—
—
0
0
632
5167
1.36
8.13
3.1
2.5
72.9
73.5
nmol/l
0.21
559
4718
466
3631
1.40
8.05
3.9
3.4
7.6
8.0
mmol/l
0.90
394
3123
77
382
2.07
7.97
5.4
6.0
1.6
1.6
%
0.09
72
354
514
4080
1.38
7.91
3.4
3.3
29.4
31.4
u/l
0.90
484
3882
51
215
2.42
7.81
4.0
3.0
1.6
1.5
mmol/l
0.25
51
210
707
5908
1.34
7.78
5.3
6.0
11.3
12.0
umol/l
0.49
655
5557
1454
13666
1.55
7.42
15.9
13.1
74.1
72.0
umol/l
1.28
1454
13661
66
319
2.11
7.34
1.3
2.4
3.7
3.6
mmol/l
0.39
61
304
424
3305
1.38
7.18
2.3
2.4
2.9
2.8
mg/l
0.14
354
2842
387
2976
1.39
7.10
4.2
4.2
15.8
9.9
mg/mmol
0.56
244
1948
544
4418
1.35
7.07
1.9
1.9
100.3
96.2
pmol/l
1.08
283
2334
258
1846
1.47
7.04
6.0
4.9
0.8
0.8
mmol/l
0.06
241
1734
1299
11983
1.40
6.99
5.3
4.4
1.9
2.0
mu/l
0.29
1199
11112
1250
11479
1.37
6.75
4.2
3.8
5.9
5.8
mmol/l
1.61
1125
10530
23
68
3.42
6.70
1.9
1.5
—
—
—
0
0
261
1891
1.45
6.66
3.3
2.4
13.2
13.8
umol/l
0.85
240
1751
63
313
2.05
6.55
1.8
2.5
2187.7
806.6
e6/l
0.55
53
243
63
313
2.05
6.55
1.7
2.5
28.0
10.4
e6/l
0.49
49
233
367
2836
1.38
6.47
3.8
3.5
1.0
1.0
kg/l
0.13
81
418
103
611
1.73
6.23
1.8
1.7
9.1
7.7
u/l
0.48
79
472
202
1415
1.49
6.11
7.6
6.2
1.5
1.7
mmol/l
0.24
163
1119
240
1746
1.44
5.97
3.3
2.4
2.5
2.4
g/l
0.83
218
1608
183
1269
1.50
5.81
2.3
2.2
370.8
373.8
nmol/l
0.07
166
1172
12
24
5.03
5.74
2.3
1.5
—
—
—
0
0
950
8483
1.28
5.71
5.3
4.1
2165.5
2826.4
e6/l
0.12
15
105
122
784
1.60
5.46
2.0
3.1
66.9
66.4
g/l
0.27
109
722
13
30
4.36
5.30
5.2
7.2
—
—
—
0
0
13
30
4.36
5.30
5.0
6.8
—
—
—
0
0
12
26
4.64
5.26
6.4
8.7
—
—
—
0
0
293
2253
1.37
5.25
1.7
1.6
39240956.5
28173149.3
pmol/l
0.10
237
1899
219
1605
1.42
5.22
3.5
2.5
21.4
23.2
%
1.13
172
1398
1442
13714
1.42
5.08
10.2
9.2
26.9
25.8
u/l
0.63
1390
13238
1561
15099
1.66
4.93
21.8
17.6
6.8
6.7
e9/l
0.74
1522
14617
323
2548
1.33
4.87
1.6
1.5
20.9
20.4
nmol/l
0.21
271
2199
161
1130
1.47
4.83
7.8
5.9
5.1
5.1
kpa
0.17
152
1072
1560
15094
1.64
4.83
21.8
17.5
4.5
4.5
e12/l
0.76
1519
14617
1559
15082
1.64
4.83
21.8
17.6
257.9
256.9
e9/l
0.23
1528
14639
160
1125
1.47
4.76
12.4
9.3
8.7
7.7
mmol/l
1.10
152
1083
724
6343
1.25
4.76
3.4
2.9
91.2
92.1
ug/l
0.04
671
5922
1401
13291
1.36
4.74
14.8
12.0
21.5
22.9
mg/l
0.84
1106
10115
332
2641
1.32
4.71
2.0
2.1
1.3
1.2
mg/l
0.09
236
1951
1560
15102
1.63
4.71
22.0
17.7
134.8
135.1
g/l
0.45
1542
14882
112
733
1.57
4.67
1.9
1.5
349.3
304.8
mu/l
0.90
104
654
156
1097
1.47
4.64
7.9
6.0
1.5
1.5
mmol/l
0.03
113
799
939
8488
1.25
4.61
3.4
3.1
41.6
40.9
u/l
0.11
877
8000
185
1356
1.41
4.41
2.6
4.0
1.6
1.7
%
0.28
155
1237
567
4865
1.25
4.38
4.8
3.5
—
—
—
0
0
115
771
1.53
4.33
2.3
2.3
6.8
6.7
ug/l
0.03
86
673
117
789
1.52
4.29
3.4
3.2
4.6
4.7
pmol/l
0.93
103
701
126
865
1.49
4.24
5.6
3.7
1.2
1.2
mmol/l
0.08
110
752
25
102
2.47
4.22
1.1
1.1
—
—
—
0
0
15
46
3.28
4.19
7.1
9.5
—
—
—
0
0
85
537
1.61
4.14
15.7
12.2
1.4
1.2
mg/l
1.02
76
507
130
905
1.47
4.09
9.3
8.4
124.5
121.8
g/l
0.68
122
874
164
1196
1.41
4.03
3.9
4.3
243.1
254.4
u/l
0.32
151
1136
455
3848
1.25
3.92
3.1
3.2
2.4
2.4
mmol/l
0.74
378
3404
29
132
2.22
3.87
1.0
1.1
—
—
—
0
0
152
1108
1.41
3.76
8.5
7.9
13.0
12.9
kpa
0.06
143
1064
152
1110
1.41
3.72
8.6
7.9
0.5
1.0
mmol/l
0.75
115
883
27
122
2.23
3.68
1.1
1.0
—
—
—
0
0
711
6345
1.21
3.60
4.6
3.4
0.0
0.0
estimate
0.00
112
1234
151
1109
1.40
3.59
8.6
7.9
4.9
5.1
kpa
1.71
143
1063
29
137
2.14
3.56
1.1
1.0
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
21
86
2.46
3.55
1.4
1.2
—
—
—
0
0
88
583
1.54
3.54
5.8
7.5
24.1
24.5
mmol/l
0.34
82
545
119
842
1.45
3.48
8.5
6.3
24.3
24.5
mmol/l
0.28
113
824
31
152
2.06
3.47
1.3
1.4
—
—
—
0
0
20
81
2.49
3.47
1.4
1.2
—
—
—
0
0
31
153
2.05
3.41
1.3
1.4
—
—
—
0
0
107
748
1.46
3.34
1.7
1.6
22.3
18.8
iu/l
0.57
88
592
42
234
1.82
3.27
3.7
2.7
16.9
16.6
%
0.19
26
132
712
6412
1.19
3.14
4.5
3.4
0.0
0.0
estimate
0.80
117
1230
55
336
1.66
3.13
4.6
4.8
24.7
24.3
mmol/l
0.41
49
301
39
673
0.57
3.10
1.4
1.5
—
—
—
0
0
1345
12862
1.25
3.06
15.5
13.1
39.1
39.9
%
2.39
916
10048
30
153
1.98
3.05
1.3
1.4
—
—
—
0
0
395
3380
1.22
2.96
4.9
3.7
0.0
0.0
estimate
1.08
116
1233
77
517
1.51
2.96
2.8
4.7
93.0
92.9
%
0.02
69
491
8
17
4.72
2.92
2.6
2.7
20.1
27.3
umol/l
—
8
17
30
156
1.94
2.90
1.3
1.4
—
—
—
0
0
44
259
1.72
2.89
1.4
1.6
0.3
0.3
nmol/l
0.11
35
211
652
5859
1.19
2.88
4.5
4.0
—
—
—
0
0
30
157
1.93
2.86
1.3
1.4
—
—
—
0
0
109
794
1.40
2.77
3.2
2.9
168.5
171.4
ng/l
0.03
98
717
1178
11159
1.20
2.72
4.0
3.4
1.3
1.2
mmol/l
0.84
1075
10363
166
1297
1.31
2.69
4.5
3.9
32.5
32.2
%
0.12
109
901
701
6365
1.18
2.69
6.3
4.7
0.0
0.0
estimate
0.50
119
1266
29
155
1.89
2.62
1.3
1.4
—
—
—
0
0
36
603
0.59
2.60
1.4
1.4
—
—
—
0
0
36
603
0.59
2.60
1.4
1.4
—
—
—
0
0
7
15
4.68
2.60
1.0
1.1
—
—
—
0
0
36
602
0.59
2.59
1.4
1.4
—
—
—
0
0
36
600
0.59
2.56
1.4
1.4
—
—
—
0
0
107
790
1.38
2.53
2.1
1.7
—
—
—
0
0
242
1998
1.25
2.53
1.3
1.2
18.0
29.1
iu/ml
2.34
75
575
124
941
1.34
2.47
2.3
2.1
11.1
11.6
nmol/l
0.25
111
818
312
2653
1.22
2.47
3.5
2.8
5169.2
5757.2
umol/l
0.07
276
2355
139
1074
1.32
2.45
2.9
3.3
10.2
10.1
g/l
0.03
129
1000
29
159
1.84
2.44
1.7
1.6
—
—
—
0
0
141
1093
1.32
2.43
1.2
1.2
134.3
146.0
iu/ml
0.11
47
413
231
1906
1.25
2.43
1.3
1.2
9.3
9.6
u/ml
0.02
91
710
428
3762
1.19
2.37
1.4
1.4
2.1
2.0
u/ml
0.04
99
910
21
105
2.01
2.31
1.0
1.2
—
—
u/ml
—
0
0
42
261
1.63
2.31
1.4
1.3
—
—
—
0
0
224
1855
1.24
2.29
2.0
1.8
—
—
—
0
0
825
7652
1.16
2.28
9.3
9.3
4.0
4.0
e9/l
0.33
713
6647
298
2545
1.21
2.26
4.7
4.5
1.9
2.5
ug/l
1.17
255
2296
5
9
5.57
2.21
2.0
1.0
13.2
9.8
pmol/l
—
5
9
48
312
1.55
2.21
1.3
2.2
9.9
10.2
g/l
0.21
34
271
8
24
3.34
2.18
1.9
2.0
—
—
—
0
0
29
166
1.76
2.16
3.3
4.2
2.4
1.0
%
0.92
23
142
64
445
1.46
2.15
1.3
1.2
0.5
1.1
u/ml
—
7
30
47
308
1.54
2.10
1.3
1.2
9.1
10.4
u/ml
—
6
51
36
221
1.64
2.10
1.9
1.5
—
—
—
0
0
128
1002
1.30
2.09
3.0
2.3
5503.7
5397.0
u/l
0.02
54
366
34
206
1.66
2.08
1.2
1.4
17.1
18.0
u/l
0.07
28
177
55
374
1.49
2.07
1.9
1.6
41.9
40.5
nmol/l
0.14
55
363
127
996
1.30
2.05
1.4
1.3
439.8
229.5
u/ml
0.52
113
914
31
184
1.70
2.05
1.8
1.5
—
—
—
0
0
7
21
3.34
1.96
1.0
1.1
—
—
—
0
0
30
179
1.69
1.96
1.5
1.3
—
—
—
0
0
19
98
1.95
1.95
3.9
3.5
62.2
54.0
%
0.92
13
72
67
482
1.41
1.91
1.3
1.4
—
—
—
0
0
234
1990
1.21
1.87
3.2
3.5
787.5
481.3
ng/l
0.30
153
1395
1232
11855
1.16
1.80
4.8
4.1
2.7
2.8
mmol/l
1.22
1122
11003
1219
11722
1.15
1.79
4.5
3.8
4.6
4.6
mmol/l
1.20
1121
10969
53
371
1.44
1.77
1.4
1.8
—
—
—
0
0
15
74
2.04
1.75
1.0
1.0
1.0
1.0
u/l
—
8
36
36
233
1.56
1.74
1.9
1.8
192.8
197.8
pmol/l
0.08
36
223
54
381
1.43
1.73
2.9
1.9
5.3
2.2
ug/l
0.65
46
336
19
103
1.85
1.72
1.6
1.4
—
—
—
0
0
143
1168
1.25
1.70
2.6
3.0
0.2
0.2
g/l
0.09
134
1096
71
528
1.36
1.69
1.6
1.8
—
—
—
0
0
66
487
1.37
1.65
1.1
1.2
0.6
2.5
u/ml
3.42
34
256
7
25
2.81
1.65
1.0
1.2
—
—
—
0
0
46
319
1.45
1.63
1.5
1.4
306.6
302.5
ug/g
0.05
28
173
37
247
1.51
1.58
1.1
1.1
16.7
182.2
iu/ml
—
9
78
48
339
1.43
1.56
1.3
2.1
3.7
3.8
g/l
0.17
26
248
48
340
1.42
1.54
1.3
2.1
7.7
7.4
g/l
0.25
27
258
48
340
1.42
1.54
1.3
2.1
—
—
—
0
0
42
290
1.46
1.53
1.7
2.3
8.9
11.4
mg/l
2.02
37
270
127
1037
1.24
1.53
9.4
7.6
1.2
1.4
mmol/l
1.33
121
978
63
470
1.35
1.50
2.3
1.9
—
—
—
0
0
12
58
2.08
1.49
1.5
1.2
—
—
—
0
0
1205
11636
1.13
1.46
4.5
3.7
1.4
1.5
mmol/l
1.04
1110
10830
86
675
1.29
1.45
1.5
1.5
—
—
—
0
0
21
126
1.68
1.40
1.6
1.4
221.9
394.8
pmol/l
0.93
14
96
57
424
1.36
1.40
2.2
1.8
—
—
—
0
0
6
23
2.61
1.37
1.3
1.6
—
—
—
0
0
6
23
2.61
1.37
1.2
1.1
—
—
—
0
0
40
282
1.43
1.34
1.1
1.1
18.1
9.8
u/ml
0.33
22
142
9
42
2.15
1.33
2.0
2.6
—
—
—
0
0
46
335
1.38
1.30
1.8
1.8
3.1
4.6
iu/l
1.23
19
118
479
4419
1.12
1.27
4.4
3.3
—
—
—
0
0
23
146
1.58
1.26
6.0
4.2
6.6
6.4
mmol/l
0.09
16
121
25
162
1.55
1.26
1.8
1.5
—
—
—
0
0
205
1790
1.17
1.25
1.9
1.7
1.4
1.4
%
0.27
188
1607
8
157
0.51
1.25
1.8
1.5
—
—
—
0
0
46
339
1.37
1.22
2.5
4.1
1.4
1.4
mmol/l
0.22
46
332
262
2336
1.14
1.21
1.5
1.4
—
—
—
0
0
42
306
1.38
1.20
2.8
2.7
—
—
—
0
0
8
38
2.11
1.18
4.8
6.1
—
—
—
0
0
43
316
1.37
1.17
1.6
1.3
—
—
—
0
0
28
190
1.48
1.16
1.3
1.4
6.9
6.9
mmol/l
0.06
19
128
0
33
0.00
1.16
0.0
1.2
—
—
—
0
0
16
259
0.61
1.14
1.1
1.1
4.5
3.4
u/ml
—
5
109
16
95
1.69
1.14
1.1
1.3
—
—
—
0
0
106
1265
0.83
1.12
1.5
1.5
—
—
—
0
0
29
411
0.70
1.11
1.3
1.3
—
—
—
0
0
16
96
1.67
1.10
1.1
1.3
—
—
—
0
0
59
461
1.29
1.08
1.7
2.1
41.4
39.1
u/l
0.38
52
417
232
2070
1.14
1.07
3.8
2.8
1.1
1.1
e6/l
0.10
141
1149
36
262
1.38
1.06
2.7
3.6
71.4
75.7
mg/l
0.04
27
211
133
1140
1.18
1.05
24.8
21.8
1.8
1.3
inr
2.20
24
165
13
75
1.74
1.03
1.2
1.2
1.0
1.1
ratio
—
6
34
5
106
0.47
1.01
2.0
2.3
—
—
—
0
0
42
317
1.33
1.00
1.3
2.1
3.0
3.1
g/l
0.47
28
251
34
248
1.38
1.00
13.4
6.3
84.4
1401.5
u/ml
—
5
20
14
84
1.67
0.98
1.5
1.2
35.3
46.1
pmol/l
—
6
20
9
50
1.80
0.96
1.0
1.3
—
—
—
0
0
12
69
1.74
0.96
1.2
1.9
—
—
—
0
0
331
3040
1.11
0.96
1.7
1.6
1.4
1.4
mmol/l
0.00
276
2620
11
62
1.78
0.94
1.2
1.2
155.4
208.9
iu/ml
0.57
11
62
35
261
1.35
0.91
4.5
3.2
19.0
27.7
mg/l
1.35
24
162
6
28
2.15
0.91
1.0
1.0
—
—
—
0
0
55
439
1.26
0.89
2.4
2.0
1.2
1.5
g/l
1.69
47
402
19
127
1.50
0.88
1.1
1.1
—
—
—
0
0
61
748
0.81
0.88
1.8
1.8
—
—
—
0
0
75
623
1.21
0.86
12.1
9.4
95.0
94.4
%
0.70
75
618
8
44
1.82
0.86
1.0
1.1
—
—
—
0
0
8
44
1.82
0.86
1.0
1.2
—
—
—
0
0
8
44
1.82
0.86
1.1
1.1
—
—
—
0
0
42
326
1.30
0.85
2.2
1.7
—
—
—
0
0
83
983
0.84
0.85
1.3
1.3
—
—
—
0
0
38
291
1.31
0.85
1.2
2.3
0.0
0.9
g/l
4.29
25
261
284
2606
1.11
0.85
3.6
2.6
5.5
7.0
e6/l
1.42
256
2304
8
45
1.78
0.84
1.0
1.3
—
—
—
0
0
8
45
1.78
0.84
1.1
1.2
—
—
—
0
0
10
57
1.76
0.83
1.7
1.4
—
—
—
0
0
13
200
0.65
0.80
1.5
1.2
—
—
—
0
0
40
312
1.29
0.80
1.1
1.1
19.9
7.3
u/ml
0.38
21
146
11
66
1.67
0.78
2.3
1.1
—
—
—
0
0
11
66
1.67
0.78
2.3
1.1
90.4
86.0
%
0.17
11
66
1192
11646
1.09
0.78
17.9
14.9
13.5
13.4
%
0.65
1161
11393
0
26
0.00
0.78
0.0
1.7
—
4.3
—
0
20
35
269
1.31
0.78
1.2
2.1
39.6
38.1
g/l
0.65
24
237
18
123
1.47
0.77
1.7
2.0
33.5
32.7
pg
0.44
18
123
22
157
1.41
0.76
1.6
1.6
—
—
—
0
0
6
34
1.77
0.76
1.2
1.4
—
—
—
0
0
6
34
1.77
0.76
4.2
3.3
—
—
—
0
0
6
34
1.77
0.76
4.2
3.3
—
—
—
0
0
28
209
1.35
0.76
1.1
1.1
—
—
—
0
0
10
59
1.70
0.76
1.7
1.4
—
—
—
0
0
10
59
1.70
0.76
1.1
1.1
—
—
—
0
0
34
262
1.30
0.75
2.8
3.6
30.3
30.8
mg/l
0.05
26
212
39
307
1.28
0.74
1.9
2.0
0.9
0.8
nmol/l
0.43
33
261
144
1284
1.13
0.72
1.9
1.8
—
—
—
0
0
11
170
0.64
0.70
1.5
1.8
—
—
—
0
0
1078
10514
1.07
0.69
3.5
3.5
—
—
—
0
0
5
27
1.85
0.68
1.0
1.2
—
—
—
0
0
40
321
1.25
0.66
2.3
1.8
—
—
—
0
0
23
305
0.75
0.66
1.4
1.5
—
—
—
0
0
11
70
1.58
0.65
1.0
1.2
116.3
439.7
u/l
1.29
11
60
7
44
1.59
0.65
2.0
2.2
17.1
17.6
umol/l
—
7
44
7
44
1.59
0.65
1.0
1.2
—
—
—
0
0
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
8
49
1.64
0.62
1.1
1.3
—
—
—
0
0
142
1281
1.12
0.61
1.9
1.7
—
—
—
0
0
50
416
1.21
0.61
1.5
1.5
—
—
—
0
0
5
30
1.67
0.61
1.0
1.1
—
—
—
0
0
8
50
1.60
0.61
1.0
1.2
—
—
—
0
0
0
20
0.00
0.60
0.0
1.8
—
2.1
—
0
8
0
20
0.00
0.60
0.0
12.0
—
—
—
0
0
218
2014
1.10
0.60
4.2
3.9
22.2
21.3
%
0.35
92
890
217
2005
1.09
0.60
4.1
3.0
5.3
3.0
e6/l
1.19
129
1089
51
427
1.20
0.59
1.0
1.1
3.1
4.4
u/ml
0.37
16
127
91
801
1.14
0.58
1.6
1.4
—
—
—
0
0
54
637
0.84
0.58
1.2
1.3
228.6
246.6
miu/ml
0.15
21
318
0
23
0.00
0.58
0.0
1.0
—
6.1
—
0
18
15
106
1.42
0.57
1.3
1.5
0.5
0.9
u/ml
—
5
39
33
265
1.25
0.57
1.0
1.1
2.6
0.4
u/ml
—
10
81
5
88
0.57
0.56
4.8
3.4
13.4
71.1
u/ml
—
5
88
17
124
1.37
0.55
3.8
1.9
—
—
—
0
0
37
304
1.22
0.53
10.6
7.3
78.2
313.8
iu/ml
—
5
41
15
108
1.39
0.53
1.1
1.2
—
—
—
0
0
15
108
1.39
0.53
1.1
1.2
—
—
—
0
0
74
649
1.15
0.52
1.6
1.6
—
—
—
0
0
11
75
1.47
0.50
1.9
1.6
—
—
—
0
0
22
171
1.29
0.50
2.9
3.0
0.9
0.8
nmol/l
0.19
14
132
26
207
1.26
0.49
1.3
1.2
1.7
3.3
u/ml
—
9
75
7
45
1.56
0.49
1.7
1.7
—
—
—
0
0
48
560
0.85
0.48
1.4
1.7
3.0
3.4
mg/l
0.19
33
381
13
93
1.40
0.48
15.6
11.0
0.6
0.6
mmol/l
0.07
13
88
211
1972
1.08
0.47
2.2
2.8
104.6
116.7
ug/g
0.31
159
1546
108
978
1.11
0.47
7.0
6.9
23.7
23.9
mmol/l
0.40
101
917
17
129
1.32
0.45
1.8
1.7
—
—
—
0
0
154
1423
1.09
0.45
3.0
3.6
6.4
7.7
umol/l
0.61
128
1207
18
138
1.31
0.45
1.3
1.2
—
0.5
nmol/l
—
0
8
12
86
1.40
0.44
2.3
1.8
—
—
—
0
0
366
3496
1.06
0.44
4.5
3.2
0.3
0.4
e6/l
0.38
287
2627
22
273
0.80
0.42
1.3
1.4
—
—
—
0
0
8
56
1.43
0.42
1.5
1.7
—
—
—
0
0
8
56
1.43
0.42
1.5
1.7
—
—
—
0
0
8
56
1.43
0.42
1.5
1.7
—
—
—
0
0
8
56
1.43
0.42
1.5
1.7
—
—
—
0
0
5
33
1.52
0.41
4.0
7.7
—
—
—
0
0
33
277
1.20
0.41
4.6
3.8
54.7
55.7
%
0.19
33
277
11
79
1.40
0.40
1.0
1.0
—
—
—
0
0
5
34
1.47
0.40
1.4
1.2
11.3
8.3
ug/l
—
5
34
20
249
0.80
0.40
1.7
1.7
4837.1
13761.7
e6/l
2.09
13
185
13
97
1.34
0.39
2.6
2.5
—
—
—
0
0
22
270
0.81
0.39
1.1
1.1
—
—
—
0
0
25
205
1.22
0.39
1.3
1.2
2.9
4.6
u/ml
0.74
15
94
0
19
0.00
0.39
0.0
4.7
—
4.2
—
0
19
9
66
1.37
0.38
1.4
1.2
—
—
—
0
0
68
609
1.12
0.38
1.5
1.6
—
—
—
0
0
32
271
1.18
0.37
3.9
3.5
3.4
3.9
e9/l
1.04
32
271
43
492
0.87
0.36
1.5
1.3
—
—
—
0
0
110
1015
1.09
0.36
1.0
1.0
—
—
—
0
0
12
90
1.34
0.35
5.3
3.9
—
—
—
0
0
14
108
1.30
0.35
1.1
1.1
—
—
—
0
0
14
108
1.30
0.35
1.1
1.1
—
—
—
0
0
12
156
0.77
0.34
1.0
1.1
—
—
—
0
0
14
109
1.29
0.33
1.1
1.2
—
—
—
0
0
60
540
1.12
0.32
1.5
1.5
—
—
—
0
0
20
164
1.22
0.32
2.3
1.9
—
—
—
0
0
120
1118
1.08
0.32
3.6
3.1
—
—
—
0
0
41
360
1.14
0.32
1.8
1.8
—
—
—
0
0
10
74
1.35
0.32
1.0
1.1
—
—
—
0
0
6
47
1.28
0.32
1.8
1.4
—
—
—
0
0
6
47
1.28
0.32
1.8
1.4
—
—
—
0
0
137
1460
0.93
0.32
2.6
2.9
0.9
0.7
ug/l
0.31
83
909
27
316
0.85
0.31
1.2
1.2
—
—
—
0
0
42
474
0.88
0.31
1.5
1.3
—
—
—
0
0
43
484
0.89
0.30
1.3
1.2
—
—
—
0
0
311
2995
1.05
0.30
2.8
2.3
—
—
—
0
0
26
223
1.17
0.28
2.3
1.9
—
—
—
0
0
8
62
1.29
0.28
2.1
1.7
—
—
—
0
0
8
63
1.27
0.27
1.0
1.0
—
—
—
0
0
8
63
1.27
0.27
2.1
1.7
—
—
—
0
0
393
3813
1.04
0.27
1.9
1.8
—
—
—
0
0
14
171
0.82
0.26
1.6
1.3
—
—
—
0
0
17
141
1.21
0.26
1.2
1.1
89.1
92.5
%
0.25
17
132
18
151
1.19
0.25
1.0
1.1
6.0
8.1
iu/ml
—
5
33
9
75
1.20
0.25
1.4
1.6
—
—
—
0
0
200
1917
1.05
0.24
2.3
2.8
2.5
2.4
mmol/l
0.62
165
1661
10
78
1.28
0.24
1.1
1.4
—
—
—
0
0
14
115
1.22
0.23
1.1
1.1
—
—
—
0
0
5
39
1.28
0.23
1.8
1.4
—
—
—
0
0
19
162
1.17
0.23
1.2
1.2
—
—
—
0
0
7
93
0.75
0.22
1.9
1.5
—
—
—
0
0
5
41
1.22
0.22
1.2
1.9
—
—
—
0
0
5
41
1.22
0.22
1.2
1.9
—
—
—
0
0
17
144
1.18
0.22
2.5
3.6
—
—
—
0
0
5
42
1.19
0.21
1.2
1.9
—
—
—
0
0
45
412
1.09
0.20
1.1
1.1
—
—
—
0
0
118
1238
0.95
0.19
1.6
1.5
—
—
—
0
0
25
281
0.89
0.19
1.4
1.4
65.5
193.2
pmol/l
1.37
25
272
24
213
1.13
0.18
1.4
1.6
—
—
—
0
0
45
415
1.09
0.18
1.1
1.1
—
—
—
0
0
7
60
1.17
0.17
2.0
1.2
—
—
—
0
0
8
69
1.16
0.16
1.4
3.0
33.9
141.2
ug/l
—
8
60
48
447
1.08
0.16
1.5
1.6
0.1
0.2
iu/ml
0.21
14
96
160
1546
1.04
0.16
1.9
2.0
—
—
—
0
0
21
187
1.12
0.16
1.4
1.1
—
—
—
0
0
42
451
0.93
0.15
1.9
1.6
152.2
206.6
u/ml
1.69
22
241
85
811
1.05
0.14
3.5
2.4
61.5
71.8
ml/min/173m2
1.39
37
292
7
88
0.79
0.14
1.6
1.5
1.0
1.0
g/l
—
7
88
30
276
1.09
0.13
3.0
3.2
34.9
35.2
umol/l
0.03
24
234
15
133
1.13
0.12
1.9
1.6
—
—
—
0
0
17
189
0.90
0.12
1.8
1.7
7.0
7.1
mmol/l
—
9
112
62
591
1.05
0.12
2.0
1.7
—
—
—
0
0
43
456
0.94
0.11
1.9
1.5
—
—
—
0
0
25
230
1.09
0.11
2.0
2.6
203.6
131.8
ug/min
0.15
15
142
14
124
1.13
0.11
1.3
1.7
55.8
57.2
%
—
6
88
297
3022
0.98
0.11
2.3
2.5
—
—
—
0
0
36
338
1.07
0.11
1.9
3.1
9.8
7.1
umol/l
0.18
26
268
11
125
0.88
0.10
1.1
1.3
—
196.7
—
0
27
11
97
1.13
0.09
3.0
1.4
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
34
321
1.06
0.09
4.7
4.6
0.3
0.4
u/ml
0.66
17
182
69
666
1.04
0.08
2.0
1.9
—
—
—
0
0
12
107
1.12
0.08
1.1
1.1
—
—
—
0
0
6
58
1.03
0.08
2.2
1.0
—
—
—
0
0
16
146
1.10
0.08
1.8
1.4
—
—
—
0
0
7
66
1.06
0.08
1.1
1.3
—
18.0
—
0
11
6
74
0.81
0.07
1.3
1.1
1799.8
1507.9
miu/ml
—
6
74
281
2775
1.02
0.07
2.2
2.3
—
—
—
0
0
92
897
1.03
0.07
3.4
4.3
2.6
17.5
ug/l
1.89
74
728
1134
11300
1.01
0.06
12.9
10.5
87.9
89.1
ml/min/173m2
0.78
893
8874
26
275
0.94
0.06
1.2
1.4
—
—
—
0
0
26
275
0.94
0.06
1.2
1.4
—
—
—
0
0
10
110
0.91
0.05
1.3
1.2
—
—
—
0
0
11
102
1.08
0.03
1.4
1.6
—
—
—
0
0
11
102
1.08
0.03
1.4
1.6
—
—
—
0
0
11
102
1.08
0.03
1.1
1.5
11.2
11.1
umol/l
0.02
11
94
11
102
1.08
0.03
1.4
1.6
—
—
—
0
0
35
342
1.02
0.01
2.2
1.6
—
—
—
0
0
25
257
0.97
0.01
1.3
1.2
—
—
—
0
0
21
204
1.03
0.00
2.4
1.7
—
—
—
0
0
28
284
0.99
0.00
1.3
1.1
—
—
—
0
0
36
364
0.99
0.00
2.3
1.7
104.8
95.8
u/ml
—
7
51
29
288
1.01
0.00
1.3
2.2
—
—
—
0
0
11
109
1.01
0.00
1.1
1.2
720.8
83.4
u/l
—
5
75
22
221
1.00
0.00
1.6
1.4
—
—
—
0
0
186
1861
1.00
0.00
2.2
2.2
—
—
—
0
0
113
1125
1.00
0.00
2.1
2.3
35.9
77.1
u/l
0.46
89
935
0
5
0.00
0.00
0.0
1.2
—
30.8
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
5
55
0.91
0.00
2.0
1.8
—
1224630.0
iu/ml
—
0
5
7
75
0.93
0.00
1.4
3.3
414.6
982.4
u/ml
—
7
75
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
6.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
9
93
0.97
0.00
2.1
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
5.3
—
424.0
—
0
6
5
57
0.88
0.00
2.2
4.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_AMBLYANOPSIA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_AMBLYANOPSIA | 1.145 [0.96, 1.36] | 0.129 |
| Birth year | 0.993 [0.98, 1.0] | 0.109 |
During the follow-up period (1.1.1998 — 31.12.2019), 491 out of 12381 females with H7_AMBLYANOPSIA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_AMBLYANOPSIA | 1.106 [0.9, 1.36] | 0.347 |
| Birth year | 0.988 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 396 out of 12315 males with H7_AMBLYANOPSIA died.
Mortality risk
Mortality risk for people of age
years, who have H7_AMBLYANOPSIA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.091% | 0.197% |
| 5 | 0.531% | 1.439% |
| 10 | 1.477% | 3.554% |
| 15 | 3.156% | 6.592% |
| 20 | 5.152% | 10.904% |
Relationships between endpoints
↥Index endpoint: H7_AMBLYANOPSIA – Amblyopia ex anopsia
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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