Amblyopia ex anopsia

H7_AMBLYANOPSIA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H53.0
  • Hospital discharge: ICD-9 3680A
  • Hospital discharge: ICD-8 37720
  • Cause of death: ICD-10 H53.0
  • Cause of death: ICD-9 3680A
  • Cause of death: ICD-8 37720

2 out of 7 registries used, show all original rules.

1700

4. Check minimum number of events

None

1700

5. Include endpoints

None

1700

6. Filter based on genotype QC (FinnGen only)

1619

Control definitions (FinnGen only)

Control exclude
H7_VISUALDISTBLIND

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H53
Name in latin
Amblyopia ex anopsia

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 31190 15645 15478
Only index persons 23884 12205 11679
Unadjusted period prevalence (%)
Whole population 0.44 0.45 0.43
Only index persons 0.45 0.45 0.45
Median age at first event (years)
Whole population 6.33 6.37 6.15
Only index persons 6.77 6.98 6.55

-FinnGen-

Key figures

All Female Male
Number of individuals 1619 1007 612
Unadjusted period prevalence (%) 0.33 0.36 0.28
Median age at first event (years) 20.31 14.21 30.34

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1700
Matched controls
17000
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H53.0
ICD-10 Finland
Amblyopia ex anopsia
6870.8
307.7
1388
11
H50.0
ICD-10 Finland
Convergent concomitant strabismus
28.5
261.4
179
70
37720
ICD-8 Finland
Other diseases of retina and optic nerve, Amblyopia
+∞
252.6
236
*
H52.0
ICD-10 Finland
Hypermetropia
14.3
245.1
235
189
37300
ICD-8 Finland
Strabismus, Concomitans convergens
56.1
220.4
125
24
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
29.5
202.2
136
50
H50.1
ICD-10 Finland
Divergent concomitant strabismus
31.8
177.3
116
39
H50.30
ICD-10 Finland
Intermittent esotropy
23.1
123.1
90
41
H52.2
ICD-10 Finland
Astigmatism
8.8
118.6
155
191
H53.1
ICD-10 Finland
Subjective visual disturbances
10.3
116.2
134
140
3680A
ICD-9 Finland
Visual disturbances, Amblyopia ex anopsia
+∞
114.9
109
*
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
19.3
105.2
83
45
H50.31
ICD-10 Finland
Intermittent exotropia
10.6
82.7
92
91
37301
ICD-8 Finland
Strabismus, Concomitans divergens
18.2
80.4
65
37
H53.2
ICD-10 Finland
Diplopia
23.1
79.5
58
26
XCK00
NOMESCO Finland
Perimetry
5.6
77.4
155
299
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.0
74.2
424
1714
Z96.1
ICD-10 Finland
Presence of intraocular lens
3.2
57.0
256
892
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.4
55.8
224
728
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.4
48.9
189
598
H52.1
ICD-10 Finland
Myopia
4.3
47.7
131
327
H54.7
ICD-10 Finland
Unspecified visual loss
18.4
44.8
36
20
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.2
40.4
432
2272
H53.9
ICD-10 Finland
Visual disturbance, unspecified
6.7
40.1
64
98
H53.4
ICD-10 Finland
Visual field defects
77.1
40.1
45
6
H25.8
ICD-10 Finland
Other senile cataract
3.1
37.2
172
604
H50.2
ICD-10 Finland
Vertical strabismus
11.9
33.5
34
29
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.0
33.5
499
2942
37001
ICD-8 Finland
Refractive errors, Hypermetropia. Hyperopia
333.4
33.0
33
*
3780A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONCOMITANS CONVERGENS]
89.4
31.8
35
*
CJB10
NOMESCO Finland
Laser discission of secondary cataract
3.1
31.1
135
456
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.9
30.2
153
564
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
11.7
29.2
30
26
Z3229
NOMESCO Finland
Other healthcare associate professional
2.6
28.4
173
702
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.2
27.9
113
366
H54.5
ICD-10 Finland
Severe visual impairment, monocular
29.1
27.6
37
13
H50.52
ICD-10 Finland
Exophoria
5.7
27.2
51
92
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
42.0
26.8
33
8
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.5
26.8
175
734
CEC00
NOMESCO Finland
Recession of extraocular muscle
28.0
24.5
33
12
H50.51
ICD-10 Finland
Esophoria
9.0
24.2
30
34
H26.4
ICD-10 Finland
After-cataract
2.7
24.0
141
561
XCK10
NOMESCO Finland
Photography of fundus of eye
2.5
21.5
147
628
37003
ICD-8 Finland
Refractive errors, Anisometropia
+∞
20.9
20
*
H25.0
ICD-10 Finland
Senile incipient cataract
3.0
19.9
88
300
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.2
19.4
166
782
H25.1
ICD-10 Finland
Senile nuclear cataract
1.8
18.7
314
1881
3503
FHL
Single muscle retroposition
15.2
18.5
30
20
XCD10
NOMESCO Finland
Electrophysiological examination of eye
4.3
18.4
47
111
Z31.5
ICD-10 Finland
Genetic counselling
2.5
18.2
117
486
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
7.3
17.8
26
36
ZXA10
NOMESCO Finland
Bilateral
1.8
17.4
296
1776
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
3.0
17.2
79
276
3671A
ICD-9 Finland
Disorders of refraction and accommodation, Myopia
+∞
16.7
16
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.6
16.4
98
393
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.2
16.1
143
683
SPAT1263
SPAT
Sampling
1.5
15.8
711
5429
3781A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS CONCOMITANS DIVERGENS]
60.6
15.8
18
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
15.7
549
3965
Q12.0
ICD-10 Finland
Congenital cataract
28.9
15.2
20
7
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.0
15.2
176
931
H53.3
ICD-10 Finland
Other disorders of binocular vision
23.6
15.1
21
9
H33.0
ICD-10 Finland
Retinal detachment with retinal break
3.6
15.1
50
143
P85
ICPC
Mental retardation
6.0
14.8
26
44
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
14.3
336
2195
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.8
14.3
224
1306
R51.80
ICD-10 Finland
Headache
1.7
14.2
289
1818
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
13.8
607
4576
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.4
13.7
93
396
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.0
13.7
149
769
XA800
NOMESCO Finland
Neuropsychological investigation
2.4
12.9
90
388
H47.2
ICD-10 Finland
Optic atrophy
19.2
12.9
19
10
SPAT1301
SPAT
No procedures
1.5
12.9
504
3698
WX140
NOMESCO Finland
Parabulbar anesthesy
2.7
12.9
67
251
3505
FHL
Single muscle resection
50.4
12.8
15
*
H26.02
ICD-10 Finland
Presenil cataract
3.6
12.7
42
120
CEC30
NOMESCO Finland
Resection of extraocular muscle
32.3
12.6
16
5
H40.0
ICD-10 Finland
Glaucoma suspect
2.2
12.5
101
465
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
3.3
12.4
45
137
3507
FHL
Retroposition and resection
16.0
12.1
19
12
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.7
11.7
236
1476
ZXA05
NOMESCO Finland
Left side
1.6
11.6
308
2067
H50.9
ICD-10 Finland
Strabismus, unspecified
9.0
11.3
23
26
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
11.1
823
6770
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.0
11.0
121
627
RL140, ,
NOMESCO Finland
5.8
11.0
20
35
XCH00
NOMESCO Finland
Eye pressure measurement
2.6
10.9
63
249
AA1AD
NOMESCO Finland
CT of head and brain
1.6
10.8
310
2114
F82
ICD-10 Finland
Specific developmental disorder of motor function
3.7
10.8
34
94
37929
ICD-8 Finland
Blindness, one eye, specifically defined
60.4
10.6
12
*
WX704
NOMESCO Finland
Intubation
2.0
10.6
117
608
SPAT1262
SPAT
Handing over of treatment supplies
1.7
10.5
218
1375
N03AX14
ATC
levetiracetam; systemic
2.8
10.3
51
186
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
4.9
10.3
22
45
H44.2
ICD-10 Finland
Degenerative myopia
18.9
10.3
15
8
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.8
10.2
51
187
ZXA00
NOMESCO Finland
Right side
1.5
10.2
329
2303
S01ED51
ATC
timolol, combinations; ophthalmic
2.1
10.0
93
453
H26.2
ICD-10 Finland
Complicated cataract
4.8
10.0
22
46
Q21.10
ICD-10 Finland
Persistent ostium secundum
4.1
10.0
27
67
CEC20
NOMESCO Finland
Recession and advancement of extraocular muscle
40.3
10.0
12
*
114
Kela drug reimbursment
Glaucoma
2.1
10.0
100
502
S01ED01
ATC
timolol; ophthalmic
2.8
9.9
47
168
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
9.8
388
2828
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
4.6
9.8
23
51
CEC50
NOMESCO Finland
Advancement of extraocular muscle
55.3
9.7
11
*
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.3
9.6
35
107
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.1
9.6
95
475
H27.0
ICD-10 Finland
Aphakia
11.4
9.6
17
15
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.1
9.4
93
465
S01EC01
ATC
acetazolamide; systemic
3.3
9.2
33
100
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
13.7
9.2
15
11
N03AG01
ATC
valproic acid; systemic, rectal
2.0
9.1
92
463
SPAT1216
SPAT
Assessment of functional ability
1.7
9.1
191
1206
Z2445
NOMESCO Finland
Psychologist
1.9
9.0
107
571
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
3.1
9.0
36
117
R62.0
ICD-10 Finland
Delayed milestone
2.8
8.9
42
150
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
8.8
381
2819
H57.1
ICD-10 Finland
Ocular pain
2.3
8.8
64
282
SFA10
NOMESCO Finland
One-surface restoration
1.4
8.8
904
7731
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
3.5
8.8
30
88
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.8
8.7
43
157
CEW99
NOMESCO Finland
Other operation on extraocular muscle
50.2
8.7
10
*
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
6.6
8.7
21
32
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.4
8.6
58
247
SPAT1312
SPAT
General health counselling
1.4
8.5
572
4568
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.6
8.5
48
188
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
3.2
8.5
33
105
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
8.5
240
1626
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.6
8.5
182
1155
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
20.1
8.5
12
6
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
8.4
1167
10432
K02.1
ICD-10 Finland
Caries of dentine
1.4
8.4
975
8475
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
4.9
8.4
18
37
F83
ICD-10 Finland
Mixed specific developmental disorders
2.8
8.4
40
144
37000
ICD-8 Finland
Refractive errors, Astigmatismus
+∞
8.3
8
*
SPAT1153
SPAT
Removal of sutures
1.4
8.1
383
2875
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
8.1
138
823
F95
ICPC
Strabismus
22.1
8.0
11
5
N03AX12
ATC
[U] gabapentin; oral
1.6
8.0
191
1246
CKC12
NOMESCO Finland
Photocoagulation of retina
2.5
7.9
50
207
N02BF01
ATC
gabapentin; oral
1.9
7.9
100
545
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.9
7.9
100
545
SPAT1245
SPAT
Provision of support and information to patient’s family members
2.3
7.9
57
251
N05BA09
ATC
clobazam; oral
4.0
7.9
22
56
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
4.0
7.9
22
56
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.7
7.9
131
777
TAB00
NOMESCO Finland
Lumbar puncture
2.1
7.8
70
337
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
7.8
283
2021
3768
FHL
Eye examination under general anesthesia
45.2
7.7
9
*
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
7.7
580
4701
Z2446
NOMESCO Finland
Social worker
1.7
7.7
140
852
F84.9
ICD-10 Finland
Pervasive developmental disorder, unspecified
4.5
7.7
18
40
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.3
7.6
57
255
S01EC03
ATC
dorzolamide; ophthalmic
4.0
7.6
21
53
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.9
7.6
88
466
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
7.6
691
5760
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
3.6
7.6
24
67
Z3231
NOMESCO Finland
Registered nurse
1.4
7.5
413
3180
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
7.5
290
2095
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
8.4
7.3
15
18
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
4.2
7.3
19
46
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
7.3
344
2580
XF602
NOMESCO Finland
Bloodpressure monitoring
3.3
7.3
27
84
R1410
NOMESCO Finland
Drawing up a rehabilitation plan
4.3
7.2
18
42
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.5
7.2
200
1349
SPAT1310
SPAT
Counselling related to known health issue
1.4
7.2
504
4031
N03AX11
ATC
topiramate; oral
2.5
7.2
43
174
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.8
7.2
114
667
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.2
7.2
57
262
F80.8
ICD-10 Finland
Other developmental disorders of speech and language
4.5
7.2
17
38
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
4.5
7.2
17
38
H01AC01
ATC
somatropin; parenteral
3.1
7.2
29
95
N05BA01
ATC
diazepam; systemic, rectal
1.6
7.2
160
1026
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
3.5
7.1
24
70
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.7
7.1
137
846
G47.3
ICD-10 Finland
Sleep apnoea
1.5
7.1
248
1758
N05AX08
ATC
risperidone; systemic
1.8
7.1
113
663
N03AX16
ATC
[U] pregabalin
1.5
7.0
263
1887
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
2.8
7.0
34
124
WX400
NOMESCO Finland
Inhalation anesthesy
1.9
7.0
80
423
L28
ICPC
Limited function/disability (L)
1.5
7.0
197
1335
N06AX21
ATC
duloxetine; oral
1.6
6.9
146
923
SXC03
NOMESCO Finland
Other oral or dental procedure
3.7
6.9
21
57
RT150, ,
NOMESCO Finland
4.0
6.9
19
48
3780B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONVERGENS ALTERNANS]
13.8
6.9
11
8
ZXE20
NOMESCO Finland
More than three and less than five hours
1.6
6.9
172
1133
Z97.4
ICD-10 Finland
Presence of external hearing-aid
2.3
6.8
50
222
Z02.7
ICD-10 Finland
Issue of medical certificate
1.8
6.8
103
594
SPAT1240
SPAT
Therapeutic discussion
1.5
6.8
196
1332
602
Kela drug reimbursment
Children's severe malnutrition
3.0
6.8
29
98
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
4.1
6.8
18
44
S01FA01
ATC
atropine; ophthalmic
9.3
6.8
13
14
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
6.8
267
1935
M24.3
ICD-10 Finland
Pathological dislocation and subluxation of joint, not elsewhere classified
40.2
6.8
8
*
Q14.2
ICD-10 Finland
Congenital malformation of optic disc
40.2
6.8
8
*
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
2.6
6.7
38
150
SFA30
NOMESCO Finland
Three-surface restoration
1.3
6.7
531
4320
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
22.6
6.7
9
*
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
2.2
6.6
52
238
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.4
6.6
340
2583
SFA20
NOMESCO Finland
Two-surface restoration
1.3
6.6
866
7544
S01EA05
ATC
brimonidine; ophthalmic
2.8
6.6
31
111
SPAT1260
SPAT
Consultation of another employee
1.5
6.6
244
1747
H25.2
ICD-10 Finland
Senile cataract, morgagnian type
12.3
6.6
11
9
3781B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS DIVERGENS ALTERNANS]
12.3
6.6
11
9
N06AB04
ATC
citalopram; systemic
1.5
6.5
237
1691
UDC00
NOMESCO Finland
Ear microscopy
1.7
6.5
115
695
CHC05
NOMESCO Finland
Iridotomy
3.7
6.5
20
55
UKC02
NOMESCO Finland
Cystoscopy
1.6
6.5
157
1027
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
6.5
185
1256
3673A
ICD-9 Finland
Disorders of refraction and accommodation, Anisometropia and aniseikonia
70.1
6.4
7
*
H54.0
ICD-10 Finland
Blindness, binocular
70.1
6.4
7
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
6.4
115
697
WX002
NOMESCO Finland
Sedation and analgesia
1.5
6.4
232
1656
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
2.1
6.4
56
269
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.5
6.3
205
1429
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
8.2
6.3
13
16
N06AX16
ATC
venlafaxine; oral
1.5
6.3
191
1313
3672A
ICD-9 Finland
Disorders of refraction and accommodation, Astigmatism
+∞
6.3
6
*
SPAT1229
SPAT
Assessment of need for aid
1.9
6.2
79
432
C07AA05
ATC
propranolol; systemic
1.4
6.2
291
2176
G43.3
ICD-10 Finland
Complicated migraine
2.8
6.1
30
110
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
6.1
120
745
SPAT1053
SPAT
Memory test
1.6
6.1
132
840
F05
ICPC
Visual disturbance other
2.2
6.1
49
227
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
2.1
6.1
52
247
R42
ICD-10 Finland
Dizziness and giddiness
1.4
6.1
266
1964
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.4
6.1
311
2360
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
6.1
358
2780
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
6.0
453
3648

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
779
6017
1.54
16.71
8.9
7.5
1.22
1.22
mmol/l
0.27
656
5204
553
4014
1.56
15.37
3.8
3.2
42.62
48.40
ng/l
0.16
343
2455
452
3238
1.54
12.92
2.4
2.1
173.37
279.60
u/l
2.02
427
3053
899
7399
1.46
12.80
5.9
4.9
6.55
6.49
mmol/l
0.32
812
6825
1102
9443
1.47
12.63
6.9
6.8
82.11
82.88
u/l
0.21
1020
8890
647
5042
1.46
12.06
5.2
5.2
36.69
36.29
g/l
1.12
592
4693
695
5514
1.44
11.67
8.8
7.0
1.22
1.22
mmol/l
0.38
634
5075
71
299
2.43
10.78
1.6
2.6
—
—
—
0
0
34
95
3.63
10.66
1.5
1.4
1.87
1.79
mmol/l
0.31
29
90
287
1933
1.58
10.56
1.8
1.7
1212.60
1186.35
nmol/l
0.19
214
1453
488
3679
1.46
10.51
2.6
2.5
57.01
81.54
u/l
0.58
448
3397
631
4988
1.42
10.50
14.1
12.5
1.36
1.21
inr
2.58
184
1512
78
350
2.29
10.28
1.5
2.4
502.62
455.59
mg/l
0.28
73
332
1193
10568
1.43
10.08
4.5
3.8
14.78
14.62
pmol/l
1.38
1065
9622
418
3103
1.46
9.63
4.5
3.5
—
—
—
0
0
83
396
2.15
9.45
5.0
5.9
0.87
0.90
%
0.44
78
369
1218
10881
1.42
9.41
6.0
4.9
38.90
38.75
mmol/mol
0.19
1125
10153
1088
9549
1.39
9.22
4.5
4.0
11.18
10.56
mm/h
0.73
990
8829
82
396
2.12
9.06
5.1
5.9
1.57
1.56
%
0.04
77
366
379
2790
1.46
9.06
3.6
3.2
1787.05
1231.95
ng/l
0.99
316
2328
1445
13369
1.54
9.06
17.2
13.5
139.50
139.56
mmol/l
0.46
1408
12983
487
3763
1.41
8.92
3.8
3.4
7.57
7.92
mmol/l
0.80
414
3271
1446
13399
1.53
8.79
17.4
13.6
3.96
3.94
mmol/l
2.04
1405
12976
145
858
1.75
8.76
2.5
2.7
5.10
6.08
e9/l
0.29
108
734
535
4214
1.39
8.72
3.4
3.3
29.59
31.82
u/l
1.04
504
4007
657
5353
1.37
8.70
3.1
2.5
72.94
73.76
nmol/l
0.32
580
4883
157
959
1.70
8.47
6.1
5.0
64.06
75.83
ng/l
1.79
134
868
53
221
2.44
8.28
3.9
2.9
1.57
1.50
mmol/l
0.29
53
216
262
1826
1.51
8.15
9.6
7.3
1.16
1.13
mmol/l
0.72
243
1707
407
3101
1.41
7.94
4.0
4.0
15.14
9.98
mg/mmol
0.50
256
2022
1524
14352
1.60
7.92
14.8
11.0
—
—
—
0
0
1350
12409
1.43
7.90
5.3
4.4
1.91
1.98
mu/l
0.27
1244
11509
68
324
2.14
7.81
1.3
2.4
3.73
3.61
mmol/l
0.36
63
308
30
96
3.16
7.70
3.1
2.7
—
—
—
0
0
41
157
2.65
7.65
1.9
2.8
—
—
—
0
0
732
6150
1.33
7.63
5.2
6.0
11.54
12.43
umol/l
0.60
679
5793
387
2946
1.41
7.54
3.3
3.4
603.64
302.09
mg/l
0.50
242
1964
566
4587
1.35
7.48
1.9
1.9
99.62
96.04
pmol/l
0.93
294
2431
1035
9173
1.33
7.28
5.4
4.1
—
—
—
0
0
492
3922
1.36
7.19
3.5
2.7
—
—
—
0
0
435
3425
1.36
6.83
2.3
2.4
2.94
2.85
mg/l
0.24
363
2949
1293
11904
1.36
6.65
4.3
3.8
5.87
5.76
mmol/l
1.64
1162
10922
64
318
2.05
6.64
1.7
2.5
27.46
10.13
e6/l
0.50
50
240
64
318
2.05
6.64
1.8
2.6
2147.22
789.10
e6/l
0.55
54
250
130
807
1.66
6.62
1.4
1.4
—
—
—
0
0
264
1923
1.44
6.51
6.0
5.0
0.81
0.82
mmol/l
0.12
247
1817
376
2931
1.36
6.22
3.8
3.6
1.02
1.02
kg/l
0.11
85
441
267
1965
1.43
6.22
3.4
2.5
13.07
13.77
umol/l
0.91
247
1835
174
1187
1.52
5.96
7.5
6.0
5.10
5.10
kpa
0.02
167
1145
189
1314
1.49
5.91
2.3
2.2
365.85
372.52
nmol/l
0.17
172
1215
56
277
2.06
5.91
4.4
4.4
—
—
—
0
0
103
620
1.70
5.91
1.8
1.7
9.11
7.72
u/l
0.48
79
477
32
124
2.61
5.89
2.6
2.5
—
—
—
0
0
981
8759
1.28
5.89
5.2
4.1
2165.47
2751.78
e6/l
0.10
15
111
172
1178
1.51
5.79
7.5
6.0
7.42
7.41
ph
1.34
21
105
246
1811
1.42
5.70
3.4
2.5
2.49
2.43
g/l
0.95
224
1671
206
1472
1.45
5.61
7.5
6.2
1.60
1.63
mmol/l
0.05
170
1189
347
2721
1.35
5.46
1.9
2.1
1.28
1.21
mg/l
0.09
247
2008
1453
13743
1.39
5.44
14.7
12.1
21.41
22.98
mg/l
1.05
1153
10468
1615
15605
1.70
5.42
21.7
17.7
6.82
6.75
e9/l
0.79
1576
15106
25
89
2.84
5.42
1.5
1.6
—
—
—
0
0
1613
15584
1.68
5.37
22.0
17.8
39.62
40.41
%
1.56
1460
14663
1614
15599
1.69
5.33
21.7
17.6
89.60
89.64
fl
0.12
1595
15375
1614
15600
1.68
5.31
21.6
17.6
29.94
29.93
pg
0.02
1595
15375
62
332
1.90
5.27
5.5
6.8
1.32
1.26
mmol/l
0.18
54
287
1614
15603
1.68
5.27
21.7
17.6
4.52
4.54
e12/l
0.68
1573
15111
1613
15591
1.68
5.27
21.8
17.7
257.96
256.99
e9/l
0.24
1582
15133
125
818
1.57
5.18
2.1
3.1
67.11
66.47
g/l
0.40
112
755
1614
15610
1.67
5.16
21.9
17.8
134.73
135.07
g/l
0.43
1596
15382
226
1669
1.41
5.14
3.6
2.6
20.96
23.10
%
1.45
179
1451
972
8751
1.26
5.09
3.4
3.1
41.58
41.25
u/l
0.05
905
8246
1490
14193
1.40
4.99
10.3
9.2
26.77
25.82
u/l
0.57
1436
13708
213
1573
1.40
4.84
1.8
1.7
—
—
—
0
0
101
639
1.62
4.84
4.3
5.3
—
—
—
0
0
412
3364
1.30
4.81
4.8
3.9
7.39
7.40
ph
0.99
81
646
45
223
2.05
4.79
6.4
8.2
12.38
11.41
mmol/l
0.78
40
198
301
2357
1.34
4.74
1.7
1.6
37959635.15
26966153.42
pmol/l
0.11
245
1984
333
2646
1.32
4.74
1.6
1.5
20.85
20.38
nmol/l
0.20
278
2278
45
224
2.04
4.73
6.4
8.2
104.43
105.13
mmol/l
0.31
40
199
165
1170
1.45
4.69
12.3
9.5
8.73
7.75
mmol/l
1.02
157
1128
113
742
1.56
4.64
1.9
1.5
347.72
304.62
mu/l
0.87
105
661
138
950
1.49
4.56
7.9
6.3
—
—
—
0
0
741
6526
1.24
4.51
3.4
2.9
90.81
92.03
ug/l
0.06
687
6092
149
1046
1.47
4.47
4.2
4.1
—
—
—
0
0
85
526
1.65
4.46
5.1
4.9
0.25
0.30
g/l
0.49
44
292
147
1031
1.47
4.43
2.6
3.3
65.80
68.86
e9/l
0.48
119
767
372
3039
1.29
4.28
3.9
4.1
—
—
—
0
0
118
799
1.51
4.24
2.3
2.3
6.72
6.85
ug/l
0.04
88
699
130
899
1.48
4.22
3.2
3.3
—
—
—
0
0
129
891
1.48
4.21
8.1
6.4
24.22
24.46
mmol/l
0.53
123
872
617
5366
1.24
4.12
3.9
3.2
5.83
5.94
ph
0.40
39
479
805
7205
1.22
4.06
6.6
6.6
1.99
2.03
e9/l
0.31
724
6364
135
949
1.46
4.04
9.2
8.8
124.18
121.85
g/l
0.59
129
922
472
3993
1.25
4.04
3.1
3.2
2.37
2.36
mmol/l
0.82
395
3554
119
816
1.49
4.03
3.3
3.3
4.56
4.71
pmol/l
0.83
104
726
33
159
2.10
3.83
1.6
1.6
285.15
285.52
mosm/kgh2o
0.04
26
120
86
556
1.58
3.82
15.5
12.2
1.37
1.26
mg/l
0.83
77
525
128
909
1.44
3.65
5.5
3.8
1.23
1.23
mmol/l
0.06
111
793
799
7195
1.21
3.65
7.0
7.0
0.19
0.19
e9/l
0.18
709
6300
734
6560
1.21
3.62
7.6
7.0
—
—
—
0
0
86
564
1.55
3.61
12.9
11.2
—
—
—
0
0
157
1159
1.39
3.61
8.5
8.2
13.00
12.92
kpa
0.06
148
1112
735
6571
1.21
3.61
4.5
3.4
0.00
0.00
estimate
0.75
127
1345
157
1160
1.39
3.59
8.6
8.3
0.50
1.01
mmol/l
0.76
121
933
187
1424
1.35
3.55
2.6
3.9
1.61
1.65
%
0.23
156
1302
110
764
1.47
3.53
1.7
1.6
23.71
18.91
iu/l
0.88
91
609
83
543
1.56
3.53
2.3
3.9
22.31
21.81
s
0.41
70
490
91
608
1.52
3.52
5.8
7.4
24.10
24.47
mmol/l
0.44
85
575
141
1029
1.40
3.47
9.2
8.8
96.50
95.96
%
0.58
135
992
156
1160
1.38
3.44
8.5
8.2
4.95
5.13
kpa
1.67
148
1111
44
247
1.80
3.34
3.7
2.7
16.77
16.60
%
0.10
28
140
48
278
1.75
3.29
6.6
4.1
—
—
—
0
0
736
6624
1.20
3.26
4.5
3.4
0.00
0.00
estimate
0.80
119
1265
770
6961
1.19
3.24
6.7
6.6
0.04
0.04
e9/l
0.20
677
6002
769
6952
1.19
3.24
6.7
6.6
0.56
0.56
e9/l
0.32
677
5992
317
2624
1.26
3.22
4.2
2.9
550.33
557.45
mosm/kgh2o
0.19
283
2280
43
243
1.79
3.20
3.8
3.9
—
—
—
0
0
255
2060
1.28
3.17
1.3
1.2
18.22
29.34
iu/ml
2.53
80
613
65
414
1.59
3.13
4.6
4.9
—
—
—
0
0
244
1967
1.28
3.09
1.3
1.2
9.82
9.86
u/ml
0.00
98
732
38
210
1.83
3.05
7.7
3.7
—
—
—
0
0
676
6074
1.19
2.98
2.8
2.6
—
—
—
0
0
761
6914
1.18
2.93
7.1
6.7
30.33
30.15
%
0.16
715
6544
75
503
1.51
2.90
1.3
1.5
—
12.54
u/ml
—
0
14
202
1603
1.30
2.90
1.2
1.2
—
—
—
0
0
229
1848
1.28
2.88
2.5
2.9
29.75
29.69
s
0.07
223
1796
9
22
4.11
2.88
1.7
1.2
—
—
—
0
0
43
252
1.72
2.86
8.0
4.8
2.02
2.44
mmol/l
0.38
27
155
146
1110
1.34
2.84
2.9
3.3
10.10
10.11
g/l
0.01
134
1036
330
2782
1.23
2.83
3.4
2.8
4903.95
5648.24
umol/l
0.10
292
2494
8
18
4.46
2.79
2.6
2.8
20.05
26.52
umol/l
—
8
18
220
1774
1.28
2.79
1.4
1.4
732.73
507.50
titre
0.63
44
336
405
3493
1.21
2.77
4.9
3.7
0.00
0.00
estimate
1.08
119
1267
1220
11564
1.19
2.77
4.0
3.5
1.28
1.25
mmol/l
0.69
1110
10737
39
225
1.75
2.75
1.8
1.6
—
—
—
0
0
26
485
0.53
2.73
1.5
1.5
—
—
—
0
0
747
6804
1.17
2.73
6.7
6.5
55.27
55.19
%
0.06
704
6436
113
830
1.39
2.73
3.2
2.9
168.54
180.69
ng/l
0.12
101
751
861
7935
1.17
2.72
9.2
9.2
4.02
3.95
e9/l
0.41
745
6902
723
6571
1.17
2.71
6.3
4.7
0.00
0.00
estimate
0.50
122
1302
26
483
0.53
2.70
1.5
1.5
—
—
—
0
0
27
495
0.54
2.69
1.6
1.5
—
—
—
0
0
44
265
1.68
2.68
1.4
1.6
0.31
0.33
nmol/l
0.09
35
216
128
964
1.35
2.66
2.4
2.0
10.88
11.45
nmol/l
0.33
121
861
32
179
1.80
2.52
1.8
3.4
—
—
—
0
0
51
326
1.58
2.48
1.4
2.2
10.10
10.20
g/l
0.06
40
298
313
2672
1.21
2.37
4.6
4.5
1.90
2.54
ug/l
1.29
269
2410
66
452
1.48
2.36
1.3
1.2
0.47
1.15
u/ml
—
7
29
723
6625
1.16
2.34
7.1
6.7
2.79
2.86
%
0.38
677
6234
700
6402
1.16
2.32
7.2
6.8
0.65
0.65
%
0.01
651
6022
439
3879
1.18
2.26
1.4
1.4
2.05
2.00
u/ml
0.03
102
934
36
217
1.67
2.23
2.1
1.6
—
—
—
0
0
143
1129
1.29
2.18
1.3
1.2
134.32
146.68
iu/ml
0.11
47
421
56
380
1.49
2.13
1.9
1.6
41.98
40.60
nmol/l
0.14
56
369
78
565
1.40
2.11
2.7
2.3
—
—
—
0
0
723
6663
1.15
2.10
7.5
6.9
8.28
8.38
%
0.41
675
6287
132
1037
1.30
2.10
1.4
1.3
425.68
233.88
u/ml
0.48
117
951
129
1011
1.30
2.09
3.0
2.3
5503.68
5395.82
u/l
0.02
54
370
7
20
3.51
2.05
1.4
1.3
—
—
—
0
0
34
207
1.66
2.05
1.2
1.4
17.05
18.28
u/l
0.10
28
176
48
318
1.52
2.05
1.3
1.2
9.12
10.58
u/ml
—
6
50
9
32
2.82
2.00
1.1
1.0
8.70
6.20
mg/g
—
9
32
76
555
1.39
1.97
1.3
1.3
—
—
—
0
0
7
21
3.34
1.96
1.0
1.1
—
—
—
0
0
7
21
3.34
1.96
1.0
1.1
—
—
—
0
0
7
21
3.34
1.96
1.0
1.1
—
—
—
0
0
5
11
4.56
1.94
1.4
1.1
—
—
—
0
0
874
8197
1.14
1.89
3.7
3.3
—
—
—
0
0
7
22
3.19
1.88
3.6
1.3
—
—
—
0
0
35
222
1.59
1.82
1.3
1.6
57.04
72.74
mmol/l
1.28
25
187
241
2059
1.20
1.82
3.1
3.5
767.83
520.34
ng/l
0.24
157
1454
173
1430
1.23
1.82
1.3
1.2
—
—
—
0
0
40
262
1.54
1.82
1.1
1.1
16.67
179.90
iu/ml
—
9
79
37
238
1.57
1.82
1.9
1.8
193.11
198.42
pmol/l
0.08
37
228
412
3681
1.16
1.81
4.6
3.1
—
—
—
0
0
44
296
1.50
1.78
2.2
2.2
8.91
11.40
mg/l
1.92
38
276
19
337
0.56
1.78
3.1
2.3
—
—
—
0
0
104
812
1.30
1.77
3.0
2.7
—
—
—
0
0
1261
12141
1.15
1.76
4.5
3.8
4.56
4.62
mmol/l
1.34
1158
11379
149
1217
1.25
1.76
2.6
3.0
0.22
0.22
g/l
0.06
140
1143
106
834
1.29
1.71
1.2
1.2
—
—
—
0
0
345
3057
1.16
1.69
3.7
3.4
—
—
—
0
0
16
82
1.96
1.69
59.6
39.0
6.99
7.24
ug/l
0.18
16
73
68
502
1.37
1.69
1.1
1.2
1.01
3.22
u/ml
2.48
41
313
1274
12287
1.15
1.69
4.8
4.2
2.71
2.76
mmol/l
1.31
1161
11430
31
195
1.60
1.69
1.3
1.6
—
—
—
0
0
159
1318
1.23
1.65
11.5
9.2
—
—
—
0
0
7
25
2.81
1.65
1.7
1.4
89.14
98.28
umol/l
—
7
25
82
628
1.32
1.62
2.1
2.5
—
—
—
0
0
65
482
1.36
1.59
1.2
1.2
—
—
—
0
0
55
401
1.38
1.50
2.9
1.9
5.24
2.15
ug/l
0.65
47
353
42
293
1.44
1.47
1.1
1.1
16.80
9.75
u/ml
0.30
24
150
47
335
1.41
1.47
1.5
1.4
306.61
299.25
ug/g
0.09
28
183
1247
12051
1.13
1.46
4.5
3.8
1.44
1.46
mmol/l
0.92
1147
11231
61
456
1.35
1.44
1.1
1.1
4.24
6.91
u/ml
1.06
37
292
203
1749
1.18
1.43
2.1
1.9
—
—
—
0
0
97
776
1.27
1.41
1.3
1.2
—
—
—
0
0
59
441
1.35
1.40
1.1
1.1
0.70
1.57
u/ml
1.13
31
254
125
1033
1.23
1.37
5.5
4.4
0.86
0.94
%
0.15
53
345
116
951
1.24
1.37
5.2
4.2
1.00
0.56
%
1.05
51
302
6
24
2.51
1.30
2.0
1.2
—
—
—
0
0
23
145
1.59
1.29
1.2
1.3
7.00
6.59
g/l
0.29
18
111
23
145
1.59
1.29
1.2
1.3
0.47
0.36
g/l
0.77
18
110
23
145
1.59
1.29
1.2
1.3
3.42
2.40
g/l
1.38
18
110
24
153
1.58
1.29
6.0
4.1
6.53
6.63
mmol/l
0.05
17
128
114
941
1.23
1.28
1.4
1.4
—
—
—
0
0
23
146
1.58
1.26
1.2
1.3
—
—
—
0
0
8
36
2.23
1.24
1.3
2.7
—
—
—
0
0
48
356
1.36
1.23
2.5
4.1
1.44
1.34
mmol/l
0.23
48
349
12
63
1.91
1.23
1.2
1.2
150.15
211.56
iu/ml
0.74
12
63
437
4018
1.12
1.22
2.8
2.4
—
—
—
0
0
113
939
1.22
1.20
5.8
4.6
0.23
0.50
%
0.31
44
242
6
26
2.31
1.18
1.2
2.0
—
—
—
0
0
38
273
1.40
1.18
2.8
3.7
69.39
76.98
mg/l
0.09
29
220
43
316
1.37
1.17
1.4
1.2
—
—
—
0
0
16
95
1.69
1.14
2.0
1.2
—
—
—
0
0
30
208
1.45
1.13
3.2
4.0
—
—
—
0
0
504
4690
1.11
1.12
2.1
2.0
—
—
—
0
0
11
58
1.90
1.12
1.0
1.4
152.80
137.40
nmol/l
0.58
11
58
117
986
1.20
1.10
5.7
4.5
0.23
0.11
%
0.60
47
296
46
346
1.34
1.10
1.8
1.8
3.11
4.65
iu/l
1.31
19
121
57
726
0.78
1.08
1.3
1.6
—
—
—
0
0
165
1436
1.17
1.07
1.7
1.5
—
—
—
0
0
43
322
1.34
1.06
1.9
2.1
0.83
0.76
nmol/l
0.35
37
275
10
52
1.93
1.06
2.0
1.6
—
—
—
0
0
19
121
1.58
1.05
1.4
1.2
—
—
—
0
0
7
33
2.13
1.05
4.3
9.6
—
—
—
0
0
12
67
1.80
1.04
3.7
7.6
—
—
—
0
0
16
98
1.64
1.03
1.3
1.2
—
—
—
0
0
25
171
1.47
1.02
3.2
4.6
—
—
—
0
0
106
893
1.20
1.01
1.8
1.8
1.18
1.30
g/l
0.27
93
832
12
68
1.77
1.00
1.6
1.7
1.22
1.12
nmol/l
—
6
56
7
35
2.00
1.00
5.7
6.2
—
—
—
0
0
9
49
1.84
0.98
1.6
1.2
—
—
—
0
0
5
23
2.18
0.98
1.4
1.5
6.72
7.22
mmol/l
—
5
13
13
77
1.69
0.95
1.2
1.2
1.04
1.07
ratio
—
6
37
14
85
1.65
0.94
1.5
1.2
180.79
186.41
pmol/l
0.06
14
85
8
145
0.55
0.93
1.1
1.4
—
—
—
0
0
10
55
1.82
0.92
2.2
1.3
—
—
—
0
0
42
323
1.31
0.90
1.1
1.1
17.71
6.46
u/ml
0.40
24
185
72
593
1.22
0.89
5.7
3.2
—
—
—
0
0
79
657
1.21
0.89
11.9
10.1
95.00
94.53
%
0.63
79
652
5
105
0.47
0.88
1.4
1.5
—
—
—
0
0
340
3141
1.10
0.88
1.7
1.7
1.36
1.36
mmol/l
0.01
285
2701
18
265
0.68
0.88
1.1
1.1
4.48
3.43
u/ml
—
5
112
59
476
1.25
0.88
1.1
1.1
—
—
—
0
0
8
43
1.86
0.87
1.0
1.5
—
—
—
0
0
36
273
1.33
0.86
2.9
3.7
29.77
33.68
mg/l
0.36
28
221
30
221
1.36
0.85
1.6
1.5
1.26
0.69
g/l
0.40
23
176
36
274
1.32
0.84
4.4
3.2
18.62
27.28
mg/l
1.41
25
170
6
112
0.53
0.83
1.0
1.0
3.70
3.02
kpa
—
6
95
1265
12370
1.09
0.81
17.7
15.2
333.82
333.23
g/l
1.45
1252
12257
8
48
1.67
0.78
2.3
3.4
—
—
—
0
0
236
2155
1.11
0.78
3.7
2.8
1.03
1.12
e6/l
0.14
144
1199
56
458
1.23
0.76
2.4
2.0
1.22
1.48
g/l
1.86
48
416
18
124
1.46
0.75
1.1
1.0
—
—
—
0
0
19
133
1.43
0.73
1.6
1.7
—
—
—
0
0
7
38
1.85
0.73
2.1
2.3
—
—
—
0
0
1263
12371
1.08
0.73
17.7
14.8
14.58
14.33
%
0.88
1238
12137
205
2248
0.90
0.73
1.5
1.6
—
—
—
0
0
36
281
1.29
0.73
1.2
2.1
39.62
38.05
g/l
0.78
26
254
71
599
1.19
0.72
1.0
1.1
—
—
—
0
0
7
39
1.80
0.72
1.1
1.2
—
—
—
0
0
9
56
1.61
0.72
1.0
1.1
—
—
—
0
0
144
1288
1.13
0.69
1.2
1.3
—
—
—
0
0
14
93
1.51
0.69
1.2
1.1
—
—
—
0
0
5
27
1.85
0.68
2.0
1.6
—
—
—
0
0
5
27
1.85
0.68
2.2
2.1
—
—
—
0
0
16
110
1.46
0.68
1.3
1.4
7.43
5.50
u/ml
—
9
60
23
170
1.36
0.67
1.1
1.4
2.04
3.78
u/ml
0.41
11
95
161
1454
1.12
0.67
1.7
1.8
—
—
—
0
0
35
276
1.27
0.67
1.1
1.1
2.16
0.41
u/ml
0.38
12
107
24
317
0.75
0.66
1.5
1.1
—
—
—
0
0
24
315
0.76
0.64
1.5
1.1
—
—
—
0
0
53
441
1.21
0.64
1.1
1.1
2.71
3.15
u/ml
0.17
32
288
13
87
1.50
0.63
1.1
1.0
—
—
—
0
0
29
225
1.29
0.63
1.0
1.1
—
—
—
0
0
37
458
0.80
0.63
1.1
1.2
—
—
—
0
0
12
79
1.52
0.62
2.9
2.1
—
—
—
0
0
18
130
1.39
0.61
1.7
1.9
33.50
32.55
pg
0.59
18
130
11
163
0.67
0.60
1.9
1.8
—
—
—
0
0
363
3427
1.08
0.59
1.6
1.5
2.19
2.10
g/l
0.25
217
2007
289
2705
1.08
0.59
3.6
2.7
5.41
6.93
e6/l
1.67
265
2438
7
114
0.61
0.58
1.0
1.0
—
—
—
0
0
219
2029
1.09
0.57
2.2
2.7
103.93
116.18
ug/g
0.33
166
1593
225
2421
0.92
0.57
1.7
1.8
—
—
—
0
0
11
73
1.51
0.56
1.0
1.2
116.27
428.17
u/l
1.31
11
63
6
37
1.62
0.55
1.7
1.7
—
—
—
0
0
15
107
1.41
0.55
1.7
1.2
—
—
—
0
0
8
122
0.65
0.54
1.4
1.3
—
—
—
0
0
77
873
0.88
0.52
1.7
1.5
—
—
—
0
0
15
203
0.74
0.51
3.5
2.5
—
—
—
0
0
211
1964
1.08
0.51
1.8
1.6
—
—
—
0
0
18
136
1.33
0.49
2.6
3.6
—
—
—
0
0
7
45
1.56
0.49
2.0
2.2
17.14
16.84
umol/l
—
7
45
19
145
1.31
0.49
1.2
1.2
—
—
—
0
0
11
76
1.45
0.48
2.7
1.9
—
—
—
0
0
21
267
0.78
0.48
1.3
1.2
—
—
—
0
0
57
655
0.87
0.47
1.2
1.3
219.74
249.00
miu/ml
0.28
22
324
15
111
1.35
0.46
1.1
1.1
—
—
—
0
0
222
2081
1.08
0.46
4.0
2.9
5.25
2.93
e6/l
1.24
133
1131
19
147
1.30
0.45
4.0
4.0
—
—
—
0
0
13
95
1.37
0.43
15.6
11.2
0.62
0.61
mmol/l
0.08
13
90
57
499
1.15
0.43
3.2
2.3
—
—
—
0
0
14
185
0.75
0.43
1.5
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
8
59
1.36
0.41
1.0
1.1
—
—
—
0
0
325
3103
1.06
0.40
2.8
2.3
—
—
—
0
0
28
232
1.21
0.40
1.1
1.1
—
—
—
0
0
5
35
1.43
0.39
2.2
1.0
—
—
—
0
0
5
35
1.43
0.39
2.2
1.0
—
—
—
0
0
5
35
1.43
0.39
2.2
1.0
—
—
—
0
0
14
182
0.77
0.39
1.7
1.5
—
—
—
0
0
411
3955
1.05
0.38
4.6
3.3
31.75
73.84
e6/l
1.43
329
3017
25
206
1.22
0.38
1.3
1.2
2.93
4.59
u/ml
0.72
15
95
5
37
1.35
0.37
1.4
1.4
67.40
92.57
nmol/24h
—
5
37
48
421
1.14
0.37
1.7
1.5
0.23
0.23
g/l
0.02
43
398
136
1460
0.93
0.36
1.2
1.3
—
—
—
0
0
22
267
0.82
0.36
1.2
1.1
—
—
—
0
0
50
565
0.88
0.36
2.2
1.8
—
—
—
0
0
335
3214
1.05
0.36
4.3
4.5
90.98
90.51
%
0.13
325
3133
5
78
0.64
0.35
1.4
1.2
—
—
—
0
0
15
190
0.79
0.35
1.7
1.3
—
—
—
0
0
6
42
1.43
0.35
1.2
1.3
—
—
—
0
0
5
79
0.63
0.35
1.4
1.2
1.71
1.56
g/l
—
5
79
210
1989
1.06
0.35
2.3
2.8
2.45
2.44
mmol/l
0.63
171
1727
11
145
0.76
0.34
1.2
1.2
—
—
—
0
0
22
181
1.22
0.34
2.9
3.0
0.90
0.85
nmol/l
0.14
14
138
34
293
1.16
0.33
4.5
3.7
54.24
55.97
%
0.35
34
293
6
90
0.67
0.32
1.2
1.6
—
—
—
0
0
12
92
1.31
0.32
1.0
1.0
—
—
—
0
0
96
889
1.08
0.30
2.5
1.8
—
—
—
0
0
7
54
1.30
0.30
2.3
3.3
—
—
—
0
0
33
287
1.15
0.30
3.8
3.4
3.38
3.97
e9/l
1.31
33
287
145
1538
0.94
0.30
2.6
2.9
0.84
0.75
ug/l
0.25
89
966
157
1483
1.06
0.30
3.0
3.6
6.40
7.72
umol/l
0.63
130
1257
8
108
0.74
0.29
6.3
4.0
—
—
—
0
0
8
109
0.73
0.29
1.6
1.2
—
—
—
0
0
10
76
1.32
0.28
1.1
1.7
15.08
3.00
u/ml
—
10
76
11
85
1.30
0.28
1.0
1.0
—
—
—
0
0
17
140
1.22
0.27
2.5
1.8
—
—
—
0
0
16
131
1.22
0.27
1.3
1.6
48.43
58.96
%
—
7
93
19
159
1.20
0.26
1.0
1.1
6.02
9.17
iu/ml
—
5
35
30
342
0.87
0.26
1.4
1.2
—
—
—
0
0
13
104
1.25
0.26
1.2
1.4
176529.87
172464.60
e6/l
—
8
72
17
141
1.21
0.26
1.2
1.3
—
—
—
0
0
17
141
1.21
0.26
1.2
1.2
0.44
4.85
u/ml
—
10
64
6
81
0.74
0.24
1.3
1.3
7.48
6.63
mmol/l
—
6
75
18
152
1.19
0.23
1.3
1.3
—
0.50
nmol/l
—
0
9
373
3628
1.04
0.23
4.5
3.2
0.30
0.37
e6/l
0.46
297
2748
20
171
1.17
0.23
1.5
1.3
2.51
13.36
u/ml
—
9
85
10
125
0.80
0.23
1.0
1.0
7.33
8.14
mu/l
—
10
107
21
181
1.16
0.22
1.2
1.3
—
—
—
0
0
7
91
0.77
0.22
1.6
1.5
0.97
0.99
g/l
—
7
91
7
93
0.75
0.22
2.9
2.3
—
—
—
0
0
5
40
1.25
0.22
1.6
1.3
—
—
—
0
0
40
362
1.11
0.22
6.4
9.1
—
—
—
0
0
5
41
1.22
0.22
2.0
1.9
0.52
25.97
u/ml
—
5
32
13
107
1.22
0.21
1.1
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
7.12
—
0
6
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
99
935
1.06
0.21
3.3
4.2
2.70
16.97
ug/l
1.90
79
757
23
201
1.15
0.21
1.5
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
20
174
1.15
0.19
1.7
1.6
—
—
—
0
0
37
338
1.10
0.18
3.4
2.6
—
—
—
0
0
23
205
1.12
0.17
2.4
1.4
—
—
—
0
0
5
70
0.71
0.16
1.4
1.2
—
—
—
0
0
12
141
0.85
0.16
1.5
1.6
—
—
—
0
0
8
72
1.11
0.16
1.4
2.9
33.88
135.07
ug/l
—
8
63
11
130
0.85
0.16
1.1
1.3
—
296.00
—
0
5
11
130
0.85
0.16
1.1
1.3
—
196.67
—
0
27
6
76
0.79
0.15
1.3
1.1
1799.83
1531.14
miu/ml
—
6
76
9
80
1.13
0.15
2.8
2.6
46.89
40.98
%
—
9
47
37
342
1.08
0.15
2.1
3.1
9.93
7.29
umol/l
0.18
27
272
7
87
0.80
0.14
1.0
1.5
—
—
—
0
0
26
285
0.91
0.14
1.4
1.4
64.27
197.47
pmol/l
1.49
26
276
44
469
0.94
0.13
1.5
1.6
—
—
—
0
0
85
887
0.96
0.13
1.3
1.3
—
—
—
0
0
23
209
1.10
0.13
1.0
1.1
—
—
—
0
0
26
238
1.09
0.13
2.0
2.4
192.21
130.53
ug/min
0.13
16
144
149
1447
1.03
0.12
1.2
1.2
—
—
—
0
0
633
6394
0.98
0.11
11.2
9.5
0.00
0.00
e9/l
0.18
513
5148
10
86
1.16
0.11
3.2
2.7
43310.00
40660.66
ug/l
—
10
86
45
426
1.06
0.11
1.1
1.2
—
—
—
0
0
124
1205
1.03
0.10
1.4
1.5
—
—
—
0
0
353
3581
0.98
0.10
7.1
7.4
—
—
—
0
0
17
154
1.10
0.10
2.1
3.4
0.23
0.19
e9/l
0.43
12
124
5
45
1.11
0.09
1.0
1.3
—
5.33
%
—
0
12
373
3779
0.98
0.09
2.0
2.1
—
—
—
0
0
5
48
1.04
0.09
1.2
1.2
—
—
—
0
0
108
1050
1.03
0.09
2.4
1.8
—
—
—
0
0
7
65
1.08
0.08
1.3
1.4
—
—
—
0
0
17
156
1.09
0.08
2.1
3.4
468.25
571.31
e6/l
0.53
12
123
25
265
0.94
0.07
1.7
1.7
3940.35
13697.19
e6/l
2.82
17
198
13
119
1.09
0.06
6.5
9.9
12.30
11.54
%
0.47
13
119
110
1121
0.98
0.05
1.9
1.8
—
—
—
0
0
362
3590
1.01
0.05
4.3
3.1
—
—
—
0
0
451
4483
1.01
0.04
3.0
2.5
—
—
—
0
0
114
1123
1.02
0.04
2.3
1.8
—
—
—
0
0
28
269
1.04
0.04
1.3
1.2
—
—
—
0
0
19
180
1.06
0.04
2.4
3.4
1.44
1.41
e9/l
0.08
14
150
437
4346
1.01
0.04
1.5
1.6
—
—
—
0
0
12
129
0.93
0.03
1.3
1.1
—
—
—
0
0
118
1195
0.99
0.03
6.5
3.7
—
—
—
0
0
77
757
1.02
0.03
3.4
2.4
—
—
—
0
0
128
1265
1.01
0.03
1.5
1.4
—
—
—
0
0
24
249
0.96
0.02
1.1
1.1
—
—
—
0
0
472
4738
0.99
0.02
5.3
3.8
61.54
90.47
e6/l
0.68
352
3241
299
2974
1.01
0.02
1.8
1.7
—
—
—
0
0
11
117
0.94
0.01
2.4
3.8
100.00
318.50
e6/l
—
5
80
114
1130
1.01
0.01
2.3
1.8
—
—
—
0
0
13
123
1.06
0.01
1.0
1.1
—
—
—
0
0
28
273
1.03
0.01
5.1
6.2
—
—
—
0
0
46
467
0.98
0.01
1.8
1.6
150.29
209.03
u/ml
2.07
24
248
114
1134
1.01
0.00
2.4
1.8
—
—
—
0
0
116
1166
0.99
0.00
2.0
2.3
35.97
75.52
u/l
0.45
92
965
10
105
0.95
0.00
4.0
2.3
—
—
—
0
0
10
105
0.95
0.00
1.2
1.4
27.28
32.76
g/l
—
10
94
11
105
1.05
0.00
1.1
1.5
11.20
11.15
umol/l
0.01
11
97
12
119
1.01
0.00
1.4
1.4
—
28.56
—
0
9
37
375
0.99
0.00
2.2
1.7
104.84
96.25
u/ml
—
7
52
20
204
0.98
0.00
1.1
1.1
—
—
—
0
0
37
368
1.01
0.00
3.2
3.0
—
—
—
0
0
14
137
1.02
0.00
1.2
1.3
—
—
nmol/l
—
0
0
14
143
0.98
0.00
4.8
3.5
—
—
—
0
0
39
393
0.99
0.00
2.1
1.7
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
33.51
—
0
8
8
88
0.91
0.00
1.3
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
309.25
—
0
8
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
5.0
3.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
56
0.89
-0.00
9.0
3.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.2
—
139.20
—
0
5
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.3
—
426.71
—
0
7
8
81
0.99
-0.00
1.5
1.4
6.71
6.13
ug/l
—
8
69
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
29.61
—
0
7
6
60
1.00
-0.00
2.2
1.2
—
—
—
0
0
7
75
0.93
-0.00
1.4
3.3
414.57
994.57
u/ml
—
7
75
0
7
0.00
-0.00
0.0
1.1
—
78.51
—
0
7
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
230.62
—
0
5

Mortality – FinRegistry

Association

Association between endpoint H7_AMBLYANOPSIA and mortality.

Females

Parameter HR [95% CI] p-value
H7_AMBLYANOPSIA 1.145 [0.96, 1.36] 0.129
Birth year 0.993 [0.98, 1.0] 0.109

During the follow-up period (1.1.1998 — 31.12.2019), 491 out of 12381 females with H7_AMBLYANOPSIA died.

Males

Parameter HR [95% CI] p-value
H7_AMBLYANOPSIA 1.106 [0.9, 1.36] 0.347
Birth year 0.988 [0.98, 1.0] 0.011

During the follow-up period (1.1.1998 — 31.12.2019), 396 out of 12315 males with H7_AMBLYANOPSIA died.

Mortality risk

Mortality risk for people of age

years, who have H7_AMBLYANOPSIA.

N-year risk Females Males
1 0.091% 0.197%
5 0.531% 1.439%
10 1.477% 3.554%
15 3.156% 6.592%
20 5.152% 10.904%

Relationships between endpoints

Index endpoint: H7_AMBLYANOPSIA – Amblyopia ex anopsia

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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