Generalized epilepsy

GE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G40.3
  • Hospital discharge: ICD-9 345[0-3]
  • Hospital discharge: ICD-8 34519
  • Hospital discharge: excluded ICD-8 34511
  • Cause of death: ICD-10 G40.3
  • Cause of death: ICD-9 345[0-3]
  • Cause of death: ICD-8 34519
  • Cause of death: excluded ICD-8 34511

2 out of 7 registries used, show all original rules.

1784

4. Check minimum number of events

None

1784

5. Include endpoints

None

1784

6. Filter based on genotype QC (FinnGen only)

1710

Control definitions (FinnGen only)

Control exclude
G6_EPLEPSY

Extra metadata

First used in FinnGen datafreeze
DF3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 23791 11883 11645
Only index persons 18264 9848 8416
Unadjusted period prevalence (%)
Whole population 0.33 0.34 0.33
Only index persons 0.34 0.36 0.32
Median age at first event (years)
Whole population 27.14 24.77 28.84
Only index persons 22.12 22.16 22.08

-FinnGen-

Key figures

All Female Male
Number of individuals 1710 1032 678
Unadjusted period prevalence (%) 0.34 0.37 0.31
Median age at first event (years) 27.43 24.50 31.87

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1784
Matched controls
17840
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G40
ICD-10 Finland
Epilepsy
3394.0
317.2
297
*
N03AX14
ATC
levetiracetam; systemic
246.1
307.7
547
32
N03AX09
ATC
lamotrigine; oral
16.6
307.7
539
454
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
7544.1
307.7
545
*
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
+∞
307.7
366
*
N05BA01
ATC
diazepam; systemic, rectal
8.3
307.7
612
1054
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
+∞
307.7
356
*
N03AB02
ATC
phenytoin; systemic
121.9
307.7
176
16
3451A
ICD-9 Finland
Epilepsy, Generalised convulsive epilepsy
+∞
307.7
380
*
G40.39
ICD-10 Finland
Other or unspecified generalized epileptic syndromes with atonic, clonic, myoclonic or tonic-clonic seizures
+∞
307.7
858
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
36.4
307.7
603
247
N03AG01
ATC
valproic acid; systemic, rectal
64.0
307.7
1042
383
N03AF02
ATC
oxcarbazepine; oral
88.5
307.7
490
76
G40.30
ICD-10 Finland
Benign myoclonic eplilepsy in infancy
+∞
307.7
321
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
4484.3
307.7
982
5
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
+∞
307.7
1577
*
183
Kela drug reimbursment
Lamotrigin and topiramate
+∞
307.7
501
*
G40.3
ICD-10 Finland
Generalized idiopathic epilepsy and epileptic syndromes
+∞
307.7
353
*
N03AF01
ATC
carbamazepine; oral, rectal
35.7
307.7
579
237
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
+∞
306.3
285
*
N05BA09
ATC
clobazam; oral
422.4
228.0
224
6
N88
ICPC
Epilepsy
+∞
227.0
213
*
N03AE01
ATC
clonazepam; systemic
9.5
224.1
290
359
7803A
ICD-9 Finland
General symptoms, Convulsions
25.0
218.3
156
68
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
+∞
212.9
200
*
G40.36
ICD-10 Finland
Juvenile myoclonic epilepsy [impulsive petit mal]
+∞
206.3
194
*
N03AX11
ATC
topiramate; oral
12.0
199.3
211
197
G40.6
ICD-10 Finland
Grand mal seizures, unspecified (with or without petit mal)
+∞
191.2
180
*
N05CD08
ATC
midazolam; nasal, systemic
18.2
180.6
148
88
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
12.4
173.4
178
158
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
+∞
160.9
152
*
G40.89
ICD-10 Finland
Other epilepsy
+∞
152.3
144
*
78020
ICD-8 Finland
Certain symptoms referable to nervous system and special senses, Convulsions
20.2
144.2
112
59
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
+∞
141.6
134
*
G40.10
ICD-10 Finland
Simple partial seizures
+∞
139.4
132
*
3459X
ICD-9 Finland
Epilepsy, unspecified
+∞
137.3
130
*
N03AX18
ATC
lacosamide; systemic
675.4
129.2
126
*
34599
ICD-8 Finland
Epilepsy, Other and unspecified
+∞
125.5
119
*
34519
ICD-8 Finland
Epilepsy, Generalisata convulsiva NUD
+∞
123.4
117
*
G40.09
ICD-10 Finland
Other or unspecified partial (focal) idiopathic epilepsy or epileptic syndrome with local onset
+∞
113.8
108
*
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
990.4
96.9
94
*
XA800
NOMESCO Finland
Neuropsychological investigation
5.8
93.9
183
345
AA1AD
NOMESCO Finland
CT of head and brain
3.1
93.7
517
2073
3454A
ICD-9 Finland
Epilepsy, Partial epilepsy, with impairment of consciousness[EPILEPSIA GENERALISATA SECUNDARIA]
+∞
93.6
89
*
G40.00
ICD-10 Finland
Benign childhood epilepsy with centrotemporal EEG spikes
+∞
93.6
89
*
G40.35
ICD-10 Finland
Juvenile absence epilepsy
+∞
93.6
89
*
34510
ICD-8 Finland
Epilepsy, """"Grand mal""""
+∞
91.4
87
*
3450A
ICD-9 Finland
Epilepsy, Generalised nonconvulsive epilepsy
+∞
90.4
86
*
3453A
ICD-9 Finland
Epilepsy, Grand mal status
+∞
90.4
86
*
G40.33
ICD-10 Finland
Juvenile absence epilepsy
+∞
85.1
81
*
N03AD01
ATC
ethosuximide; oral
+∞
85.1
81
*
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
+∞
84.0
80
*
XA400
NOMESCO Finland
EEG
29.8
82.7
55
19
G40.1
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
+∞
81.9
78
*
N03AX22
ATC
perampanel; oral
+∞
77.7
74
*
G41.9
ICD-10 Finland
Status epilepticus, unspecified
124.3
77.6
83
7
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
8.4
74.3
99
124
N03AX23
ATC
brivaracetam; systemic
+∞
72.4
69
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.9
72.0
237
679
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.7
63.3
221
657
N03AG04
ATC
vigabatrin; oral
+∞
61.8
59
*
N03AX15
ATC
zonisamide; oral
88.4
61.4
68
8
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.3
57.7
239
792
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
10.0
54.8
63
65
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.3
48.5
199
653
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.7
48.2
164
477
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
5.3
47.8
98
192
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
9.1
47.7
59
67
181
Kela drug reimbursment
Retigabine and vigabatrin
+∞
45.0
43
*
N05AX08
ATC
risperidone; systemic
3.1
44.6
200
691
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.7
43.7
256
1025
3454B
ICD-9 Finland
Epilepsy, Partial epilepsy, with impairment of consciousness[TEMPORAALIEPILEPTINEN POISSAOLOKOHTAUS]
+∞
42.9
41
*
R55
ICD-10 Finland
Syncope and collapse
2.9
39.8
211
800
R56.0
ICD-10 Finland
Febrile convulsions
10.7
39.4
43
41
G40.0
ICD-10 Finland
Localization-related (focal)(partial) idiopathic epilepsy and epileptic syndromes with seizures of localized onset
+∞
38.7
37
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.2
38.1
416
2193
Z2445
NOMESCO Finland
Psychologist
3.4
38.1
147
463
N05AA02
ATC
levomepromazine; systemic
4.1
37.7
107
273
34532
ICD-8 Finland
Epilepsy, Partialis (focalis) generalisata
+∞
37.6
36
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.4
37.2
282
1273
ADB00
NOMESCO Finland
Implantation of vagus nerve stimulating device
+∞
36.6
35
*
G40.11
ICD-10 Finland
Simple partial epileptic seizure that develops into a complex partial seizure
+∞
36.6
35
*
F02.89*G40.9
ICD-10 Finland
Dementia in epilepsy
+∞
36.6
35
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.0
36.0
521
3042
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.1
35.2
159
550
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.0
34.3
158
553
N05AD01
ATC
haloperidol; systemic
4.9
34.1
76
160
G41.0
ICD-10 Finland
Grand mal status epilepticus
77.7
33.9
38
5
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.3
32.6
291
1406
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
30.3
260
1234
34530
ICD-8 Finland
Epilepsy, Psychomotorica
+∞
29.2
28
*
N03AF04
ATC
eslicarbazepine; oral
+∞
29.2
28
*
N05AH03
ATC
olanzapine; systemic
2.7
29.1
163
633
34500
ICD-8 Finland
Epilepsy, """"Petit mal""""
+∞
28.2
27
*
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
27.0
265
1326
N06AB04
ATC
citalopram; systemic
2.0
26.9
366
2066
R42
ICD-10 Finland
Dizziness and giddiness
2.0
26.6
354
1982
G40.7
ICD-10 Finland
Petit mal, unspecified, without grand mal seizures
+∞
26.1
25
*
A06AD11
ATC
lactulose; oral
2.3
25.9
213
990
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.0
25.6
117
407
W19
ICD-10 Finland
Unspecified fall
2.4
25.3
195
880
F44.5
ICD-10 Finland
Dissociative convulsions
+∞
25.1
24
*
N07
ICPC
Convulsion/seizure
39.4
24.9
31
8
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.5
24.7
171
735
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.0
24.6
298
1610
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
24.6
398
2372
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
24.2
357
2062
F29
ICD-10 Finland
Unspecified nonorganic psychosis
3.0
24.0
110
383
N05AH04
ATC
quetiapine; oral
1.9
23.9
362
2109
N05CD07
ATC
temazepam; oral
2.4
23.8
170
741
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
5.5
23.1
45
84
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.5
23.0
147
608
G40.80
ICD-10 Finland
Epilepsy with continuous EEG spike-waves during slow wave sleep
+∞
23.0
22
*
G40.34
ICD-10 Finland
Epilepsy with grand mal seizures on awakening
+∞
23.0
22
*
N05AH02
ATC
clozapine; systemic
4.1
22.5
62
155
Z2446
NOMESCO Finland
Social worker
2.4
22.3
162
712
G40.8
ICD-10 Finland
Other epilepsy
+∞
21.9
21
*
34598
ICD-8 Finland
Epilepsy, Alia definita
+∞
21.9
21
*
R53
ICD-10 Finland
Malaise and fatigue
1.8
21.8
432
2725
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.2
21.8
90
295
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
6.8
21.7
34
51
R11
ICD-10 Finland
Nausea and vomiting
2.2
21.1
180
848
G40.31
ICD-10 Finland
Benign neonatal convulsions (familial)
+∞
20.9
20
*
N03AG06
ATC
tiagabine; oral
+∞
20.9
20
*
3454X
ICD-9 Finland
Epilepsy, Partial epilepsy, with impairment of consciousness[ALII DISTURBATIONES CONSCIENTAE EPILEPTICI]
+∞
20.9
20
*
4380A
ICD-9 Finland
Late effects of cerebrovascular disease[SEQUELAE MORBI CEREBROVASCULARIS]
42.2
20.5
25
6
S06.0
ICD-10 Finland
Concussion
2.1
20.3
218
1123
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
4.0
20.0
57
146
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
20.0
347
2099
G40.59
ICD-10 Finland
Other special epileptic syndromes
+∞
19.8
19
*
N03AA02
ATC
phenobarbital; systemic
74.3
19.7
22
*
F20.9
ICD-10 Finland
Schizophrenia, unspecified
3.8
19.7
61
166
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
19.7
644
4618
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
7.5
19.5
28
38
N05CD02
ATC
nitrazepam; oral
5.3
19.4
39
75
V700A
ICD-9 Finland
General medical examination, Routine general medical examination at a health care facility
3.8
18.9
57
152
N05AF03
ATC
chlorprothixene; systemic
3.6
18.5
61
173
AA1BD
NOMESCO Finland
Extensive CT of head and brain
4.5
18.3
44
99
N05BA04
ATC
oxazepam; oral
1.7
18.1
420
2751
WX892
NOMESCO Finland
Monitored bed care
2.4
18.0
131
575
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.4
17.8
125
540
N05AB03
ATC
perphenazine; systemic, rectal
3.1
17.8
76
254
G40.37
ICD-10 Finland
Baltic myoclonus
+∞
17.7
17
*
A28
ICPC
Limited function/disability NOS
2.0
17.6
199
1042
TAB00
NOMESCO Finland
Lumbar puncture
2.7
17.6
97
373
G41.2
ICD-10 Finland
Complex partial status epilepticus
181.7
17.5
18
*
C03CA01
ATC
furosemide; systemic
1.8
17.5
322
1976
N04AA02
ATC
biperiden; systemic
4.1
17.4
47
116
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.2
17.0
154
741
113
Kela drug reimbursment
Anxiety disorders associated with mental retardation
50.5
17.0
20
*
S01.0
ICD-10 Finland
Open wound of scalp
2.4
16.8
125
554
3452A
ICD-9 Finland
Epilepsy, Petit mal status
+∞
16.7
16
*
R51.80
ICD-10 Finland
Headache
1.7
16.3
311
1925
H53.4
ICD-10 Finland
Visual field defects
4.5
16.2
39
88
E950A
ICD-9 Finland
Suicide and self-inflicted poisoning by solid or liquid substances
5.8
15.9
29
51
A04
ICPC
Weakness/tiredness general
1.8
15.3
262
1570
T90.5
ICD-10 Finland
Sequelae of intracranial injury
5.3
15.2
30
57
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.6
15.1
92
372
Z3231
NOMESCO Finland
Registered nurse
1.6
15.1
447
3093
Y0209
ICD-8 Finland
Examination of the nervous system and sensory organs, Nervous system
11.9
15.1
27
23
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
3.3
14.8
55
169
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
16.6
14.8
23
14
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
3.7
14.7
47
131
7802X
ICD-9 Finland
General symptoms, Syncope and collapse[SYNCOPE ET COLLAPSUS NUD]
13.3
14.7
25
19
G41.1
ICD-10 Finland
Petit mal status epilepticus
+∞
14.6
14
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
14.6
183
993
N05AC02
ATC
thioridazine; oral
3.6
14.4
47
133
N05AF05
ATC
zuclopenthixol; systemic
5.6
14.3
27
49
R40.2
ICD-10 Finland
Coma, unspecified
10.5
14.2
27
26
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
4.8
14.0
31
65
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.0
14.0
61
207
F70.9
ICD-10 Finland
Mild mental retardation, Without mention of impairment of behaviour
30.3
13.9
18
6
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.2
13.8
113
522
N05AX12
ATC
aripiprazole; systemic
2.3
13.8
102
452
P99
ICPC
Psychological disorders other
2.7
13.7
71
265
34539
ICD-8 Finland
Epilepsy, Partialis (focalis) NUD
+∞
13.6
13
*
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.1
13.5
125
607
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
10.1
13.5
26
26
AEA50
NOMESCO Finland
Adjustment of implanted neurostimulator
12.9
13.4
23
18
4300A
ICD-9 Finland
Subarachnoid haemorrhage[HAEMORRHAGIA SUBARACHNOID. POST ANEURYSMA SACCULARE]
25.9
13.4
18
7
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
3.3
13.3
50
155
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.0
13.3
141
721
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
3.4
13.2
47
141
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
12.2
13.1
23
19
N29
ICPC
Neurological sympt/complt other
3.9
13.1
38
99
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
13.0
622
4745
SPAT1229
SPAT
Assessment of need for aid
2.4
12.9
92
401
SPAT1301
SPAT
No procedures
1.5
12.8
475
3438
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
12.6
192
1109
P76
ICPC
Depressive disorder
2.0
12.6
144
757
AAA35
NOMESCO Finland
Insertion of subdural electrodes
+∞
12.5
12
*
F83
ICD-10 Finland
Mixed specific developmental disorders
4.3
12.5
32
76
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
5.7
12.4
23
41
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
12.4
294
1917
R41.0
ICD-10 Finland
Disorientation, unspecified
3.5
12.4
42
122
L28
ICPC
Limited function/disability (L)
1.8
12.4
211
1259
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
4.1
12.3
33
81
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.9
12.3
158
863
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
3.5
12.1
41
119
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
3.7
12.1
38
105
F40.9
ICD-10 Finland
Phobic anxiety disorder, unspecified
5.7
12.0
22
39
AA5DR
NOMESCO Finland
Brain metabolism PET with CT
47.0
11.9
14
*
SPAT1254
SPAT
Administration of medicine
1.7
11.8
235
1465
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
1.9
11.8
142
760
G81.9
ICD-10 Finland
Hemiplegia, unspecified
5.2
11.7
24
47
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
5.2
11.7
24
47
WX730
NOMESCO Finland
Conventional respirator
4.8
11.7
26
55
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
11.6
158
880
3458X
ICD-9 Finland
Epilepsy, Other forms of epilepsy
+∞
11.5
11
*
2402
FHL
External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)
4.4
11.5
28
64
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.6
11.4
67
267
RS222, ,
NOMESCO Finland
4.2
11.3
30
73
N28
ICPC
Limited function/disability (N)
4.4
11.2
28
65
R60.9
ICD-10 Finland
Oedema, unspecified
2.4
11.2
74
312
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.2
11.2
97
460
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.8
11.0
182
1075
N05CF01
ATC
zopiclone; oral
1.5
11.0
425
3088
A46
ICD-10 Finland
Erysipelas
1.8
11.0
179
1054
ZXD05
NOMESCO Finland
Urgent procedure
1.5
10.8
485
3629
3050A
ICD-9 Finland
Nondependent abuse of drugs, Alcohol abuse
5.2
10.8
22
43
79399
ICD-8 Finland
Observation, without need for further medical care, Unspecified
5.2
10.8
22
43
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.0
10.8
115
590
XCK00
NOMESCO Finland
Perimetry
2.3
10.7
78
343
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
28.2
10.7
14
5
F71.0
ICD-10 Finland
Moderate mental retardation, with the statement of no, or minimal, impairment of behaviour
28.2
10.7
14
5
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
5.6
10.7
20
36
A10AB01
ATC
insulin (human); parenteral
2.5
10.7
69
288
J01EA01
ATC
trimethoprim; systemic
1.5
10.7
374
2662
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
10.6
377
2691
P85
ICPC
Mental retardation
11.3
10.5
19
17
ZY010
NOMESCO Finland
Hospital outpatient
2.0
10.5
119
624
G25.0
ICD-10 Finland
Essential tremor
3.2
10.4
40
126
C71.11
ICD-10 Finland
Malignant tumor of frontal lobe grade II glioma
110.7
10.4
11
*
G40.50
ICD-10 Finland
Epilepsia partialis continua [Kozhevnikof]
+∞
10.4
10
*
34520
ICD-8 Finland
Epilepsy, Status epilepticus
+∞
10.4
10
*
N03AX25
ATC
cenobamate; oral
+∞
10.4
10
*
G40.51
ICD-10 Finland
Epileptic seizures related to alcohol
+∞
10.4
10
*
R32
ICD-10 Finland
Unspecified urinary incontinence
3.2
10.3
40
127
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
10.3
486
3666
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
10.2
375
2694
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
5.3
10.1
20
38
L17
ICPC
Foot/toe symptom/complaint
1.5
10.1
422
3108
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
2.9
10.1
47
166
P29
ICPC
Psychological sympt/compl other
1.8
10.1
157
912
N91.4
ICD-10 Finland
Secondary oligomenorrhoea
5.0
10.1
21
42
N01
ICPC
Headache
1.6
10.0
250
1646
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.6
9.9
223
1433
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
3.3
9.9
36
110
N06AX16
ATC
venlafaxine; oral
1.6
9.8
242
1589
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
9.8
264
1771
F61.0
ICD-10 Finland
Mixed personality disorders
3.1
9.8
39
126
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.6
9.8
226
1461
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.7
9.7
170
1021
SPAT1240
SPAT
Therapeutic discussion
1.6
9.7
212
1351
SPAT1210
SPAT
Application of cast or individual aid
2.3
9.7
69
301
C07AA05
ATC
propranolol; systemic
1.5
9.7
338
2399
S42.2
ICD-10 Finland
Fracture of upper end of humerus
2.5
9.7
62
258
6489X
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Other current conditions classifiable elsewhere
13.4
9.7
16
12
SPAT1216
SPAT
Assessment of functional ability
1.7
9.7
177
1077
P72
ICPC
Schizophrenia
2.9
9.6
43
149
F44.9
ICD-10 Finland
Dissociative [conversion] disorder, unspecified
4.5
9.6
23
52
F81.3
ICD-10 Finland
Mixed disorder of scholastic skills
4.8
9.5
21
44
OAB43, ,
SPAT
0.7
9.5
364
4881
R25.2
ICD-10 Finland
Cramp and spasm
3.0
9.5
42
144
A29
ICPC
General symptom/complaint other
1.7
9.5
175
1066
N03AX12
ATC
[U] gabapentin; oral
1.6
9.5
219
1416
G43.9
ICD-10 Finland
Migraine, unspecified
1.9
9.4
128
713
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
2.8
9.4
47
173
3069, ,
Kela drug reimbursment
+∞
9.4
9
*
96698
ICD-8 Finland
Other antiepileptics
+∞
9.4
9
*
1541, ,
Kela drug reimbursment
+∞
9.4
9
*
AAJ99
NOMESCO Finland
Other operation for epilepsy
+∞
9.4
9
*
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
3.2
9.3
36
114
7819X
ICD-9 Finland
Symptoms involving nervous and musculoskeletal systems, Other symptoms involving nervous and musculoskeletal systems[SYMPTOMATA ALIA SYSTEMATIS NERVORUM ET MUSCULOSCEL]
6.9
9.3
22
32
R4150
NOMESCO Finland
Neuropsychological rehabilitation
4.7
9.3
21
45
S30.0
ICD-10 Finland
Contusion of lower back and pelvis
2.2
9.3
77
359
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
2.2
9.2
75
347
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.0
9.2
94
475
S01.9
ICD-10 Finland
Open wound of head, part unspecified
3.3
9.2
33
100
S70.0
ICD-10 Finland
Contusion of hip
2.5
9.2
56
228
A10AA02, ,
ATC
2.5
9.2
55
222
Z3229
NOMESCO Finland
Other healthcare associate professional
1.9
9.2
121
668
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
3.6
9.1
29
81
M79.6
ICD-10 Finland
Pain in limb
1.4
9.1
613
4904
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
9.0
213
1383
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
9.0
333
2388
R1250
NOMESCO Finland
Evaluation of functional capability
2.9
9.0
42
149
S82.6
ICD-10 Finland
Fracture of lateral malleolus
2.0
8.9
96
494
C71.10
ICD-10 Finland
Malignant tumor in frontal lobe without histology
18.7
8.9
13
7
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
7.5
8.9
20
27
YX8VG
NOMESCO Finland
Stereotactic MRI exmaination with high intensity magnet for dose design of radiotherapy
24.1
8.9
12
5
78259
ICD-8 Finland
Symptoms referable to cardiovascular and lymphatic system, Syncope (lipothymia) alia sive NUD
24.1
8.9
12
5
2161
FHL
Neck ligation, big brain
24.1
8.9
12
5
D64.9
ICD-10 Finland
Anaemia, unspecified
1.9
8.9
114
623
N03AX16
ATC
[U] pregabalin
1.5
8.8
302
2131
Z02.4
ICD-10 Finland
Examination for driving licence
0.5
8.7
110
1916
N18
ICPC
Paralysis/weakness
3.7
8.7
27
74
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
8.7
146
866
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
2.7
8.7
47
180
N99
ICPC
Neurological disease other
4.3
8.7
22
52
SPAT1263
SPAT
Sampling
1.4
8.6
653
5310
F20.0
ICD-10 Finland
Paranoid schizophrenia
4.8
8.6
19
40
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.3
8.6
65
292
R60.0
ICD-10 Finland
Localized oedema
1.7
8.6
144
855
30300
ICD-8 Finland
Alcoholism, Episodic excessive drinking
8.3
8.6
18
22
RS221, ,
NOMESCO Finland
3.1
8.6
35
115
N03AA03
ATC
primidone; oral
16.4
8.6
13
8
R50.9
ICD-10 Finland
Fever, unspecified
1.5
8.5
249
1698
M41.4
ICD-10 Finland
Neuromuscular scoliosis
20.1
8.5
12
6
9694A
ICD-9 Finland
Poisoning by psychotropic agents, Benzodiazepine-based tranquillisers
7.4
8.4
19
26
J01DA01
ATC
[U] cefalexin
1.3
8.4
948
8172
F39
ICD-10 Finland
Unspecified mood [affective] disorder
2.7
8.4
44
166
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
2.7
8.3
43
161
G41.8
ICD-10 Finland
Other status epilepticus
+∞
8.3
8
*
3456B
ICD-9 Finland
Epilepsy, Infantile spasms[EPILEPSIA MYOCLONICA CUM ASTASIA]
+∞
8.3
8
*
V628A
ICD-9 Finland
Other psychosocial circumstances, Other psychological or physical stress, not elsewhere classified
+∞
8.3
8
*
N06AX11
ATC
mirtazapine; oral
1.4
8.3
490
3823
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
8.3
578
4633
Z3226
NOMESCO Finland
Physiotherapist
1.5
8.3
265
1844
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.2
8.3
69
323
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
14.5
8.2
13
9
J01FF01
ATC
clindamycin; systemic
1.4
8.2
380
2842
F99
ICD-10 Finland
Mental disorder, not otherwise specified
2.6
8.2
47
186
H03AA01
ATC
levothyroxine sodium; systemic
1.5
8.2
316
2283
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
6.5
8.2
20
31
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
8.2
283
2001
Z2221
NOMESCO Finland
Medical doctor
1.4
8.1
420
3200
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.8
8.1
124
716
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.7
8.1
142
853
J46
ICD-10 Finland
Status asthmaticus
2.6
8.1
46
181
IGY02
NOMESCO Finland
Psychiatric monitoring contact
2.1
8.1
76
373
K90
ICPC
Stroke/cerebrovascular accident
3.1
8.0
33
109
F20.04
ICD-10 Finland
Paranoid schizophrenia with partial recurrence
4.3
7.9
20
47
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
2.7
7.9
42
160
N06AB10
ATC
escitalopram; oral
1.4
7.9
361
2691
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.7
7.9
155
962
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
7.9
277
1965
Z30.0
ICD-10 Finland
General counselling and advice on contraception
1.7
7.8
131
777
SPAT1050
SPAT
Extensive neurological examination
3.0
7.8
34
116
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.7
7.8
139
840
S42.0
ICD-10 Finland
Fracture of clavicle
2.5
7.8
49
203
N30.0
ICD-10 Finland
Acute cystitis
1.5
7.7
231
1583
S60.2
ICD-10 Finland
Contusion of other parts of wrist and hand
1.9
7.7
95
513
F72.0
ICD-10 Finland
Severe mental retardation, with the statement of no, or minimal, impairment of behaviour
45.2
7.7
9
*
31099
ICD-8 Finland
Borderline mental retardation, Other and unspecified
45.2
7.7
9
*
C71.12
ICD-10 Finland
Malignant tumor of frontal lobe grade III glioma
45.2
7.7
9
*
78159
ICD-8 Finland
Other symptoms referable to nervous system and special senses, Laesio loquendi alia sive NUD
15.1
7.7
12
8
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
7.7
195
1287
N05AL01
ATC
sulpiride; systemic
3.6
7.7
25
71
N05AB04
ATC
prochlorperazine; systemic, rectal
3.3
7.7
28
86
Z50.5
ICD-10 Finland
Speech therapy
2.9
7.7
35
123
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
7.6
359
2688
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.8
7.6
117
677
S03.20
ICD-10 Finland
Dental dislocation
4.0
7.6
21
53
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
2.6
7.6
43
169
N91.1
ICD-10 Finland
Secondary amenorrhoea
2.6
7.6
43
169
N05BA06
ATC
lorazepam; systemic, sublingual
2.1
7.6
70
341
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.0
7.6
79
403
SPAT1172
SPAT
Guidance concerning hydration
3.5
7.6
25
72
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
10.1
7.5
14
14
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
2.6
7.5
41
159
E883A
ICD-9 Finland
Fall into hole or other opening in surface
2.1
7.4
65
311
R4120
NOMESCO Finland
Occupational therapy
1.9
7.4
95
521
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
2.0
7.4
72
359
85000
ICD-8 Finland
Concussion, Current or unspecified
2.8
7.3
35
126
F10.09
ICD-10 Finland
Alcohol intoxication UNS
2.7
7.3
38
143
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
3.1
7.3
30
99
30188
ICD-8 Finland
Personality disorders, Alia definita
8.4
7.3
15
18
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.0
7.3
72
360
R5599
NOMESCO Finland
Other rehabilitation service
2.4
7.3
47
197
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
7.3
457
3588
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
10.9
7.3
13
12
N03AF03
ATC
rufinamide; oral
+∞
7.3
7
*
N03AX17
ATC
stiripentol; oral
+∞
7.3
7
*
AAJ20
NOMESCO Finland
Excision of epileptic focus
+∞
7.3
7
*
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
7.3
344
2576
N05BA02
ATC
chlordiazepoxide; systemic
2.7
7.3
37
138
N05AD03
ATC
melperone; systemic
3.9
7.3
21
55
F05.9
ICD-10 Finland
Delirium, unspecified
3.4
7.3
25
74
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.7
7.3
126
756
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
6.3
7.2
18
29
J01DB01
ATC
cefalexin; oral
1.4
7.2
1363
12533
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
5.8
7.2
19
33
S20.2
ICD-10 Finland
Contusion of thorax
2.0
7.2
78
404
H50.1
ICD-10 Finland
Divergent concomitant strabismus
4.5
7.2
17
38
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
7.2
186
1235
L16
ICPC
Ankle symptom/complaint
1.6
7.2
184
1219
2152
FHL
Extraction, big brain
20.1
7.1
10
5
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.6
7.1
160
1027
K92.0
ICD-10 Finland
Haematemesis
2.7
7.1
36
134
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
2.4
7.1
47
200
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
4.2
7.0
18
43
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
1.9
7.0
86
465
F81.9
ICD-10 Finland
Developmental disorder of scholastic skills, unspecified
4.4
7.0
17
39
2968A
ICD-9 Finland
Affective psychoses, Manic-depressive psychosis, other and unspecified
5.5
6.9
19
35
N06AA09
ATC
amitriptyline; systemic
1.8
6.9
108
629
A10AA01, ,
ATC
2.4
6.9
46
196
W10
ICD-10 Finland
Fall on and from stairs and steps
2.0
6.8
74
383
QAB00
NOMESCO Finland
Suture of skin of head or neck
3.3
6.8
25
77
IEY08
NOMESCO Finland
Psychiatric coaching, domestic and community skills
8.3
6.8
14
17
4340A
ICD-9 Finland
Occlusion of cerebral arteries, Cerebral thrombosis
6.7
6.8
16
24
F82
ICD-10 Finland
Specific developmental disorder of motor function
3.8
6.8
20
53
U04
ICPC
Incontinence urine
2.1
6.8
58
275
43090
ICD-8 Finland
Subarachnoid haemorrhage, Postaneurysma sacculare, hypertonia non indicata
40.2
6.8
8
*
SPAT1104
SPAT
Monitoring of emergency patient
1.9
6.8
84
456
NHJ10
NOMESCO Finland
Internal fixation of fracture of ankle using wire, rod, cerclage or pin
2.1
6.8
63
309
F81.0
ICD-10 Finland
Specific reading disorder
4.3
6.8
17
40
A69
ICPC
General and Unspecified, Other reason for encounter NEC
2.4
6.7
42
174
G04BD09
ATC
trospium; oral
3.0
6.7
29
99
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
22.6
6.7
9
*
R13
ICD-10 Finland
Dysphagia
1.9
6.7
87
480
L03
ICPC
Low back symptom/complaint
1.4
6.7
409
3196
G04BD07
ATC
tolterodine; oral
2.2
6.6
54
251
E8859
ICD-8 Finland
Fall on same level from slipping, stumbling or tripping
2.4
6.6
42
175
3018D
ICD-9 Finland
Personality disorders, Other personality disorders[EPÄVAKAA PERSOONALLISUUS]
5.9
6.6
17
29
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.2
6.6
51
232
R41.3
ICD-10 Finland
Other amnesia
2.8
6.6
31
111
G44.2
ICD-10 Finland
Tension-type headache
1.5
6.6
214
1492
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
1.9
6.6
77
410
IEY01
NOMESCO Finland
Psychoeducation, individual
3.3
6.6
24
74
30040
ICD-8 Finland
Neuroses, Neurotico-depressiva
8.7
6.6
13
15
79199
ICD-8 Finland
Headache
3.8
6.5
19
50
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.6
6.5
139
881
J01CA04
ATC
amoxicillin; systemic
1.4
6.5
1426
13271
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.4
6.5
44
189
NH1BA
NOMESCO Finland
Ankle extensive X-ray examination
2.4
6.5
43
183
S63.1
ICD-10 Finland
Dislocation of finger
2.9
6.5
29
101
S82.8
ICD-10 Finland
Fractures of other parts of lower leg
2.2
6.5
51
234
U02
ICPC
Urinary frequency/urgency
1.5
6.5
188
1280
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.5
6.4
191
1306
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.8
6.4
89
500
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
6.4
867
7550
SPAT1251
SPAT
Organisation of medication
2.3
6.4
47
209
3141A
ICD-9 Finland
Hyperkinetic syndrome of childhood, Hyperkinesis with developmental delay
70.1
6.4
7
*
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
3.3
6.4
23
70
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.8
6.4
92
523
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.2
6.4
54
255
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
6.4
120
736
C02AC05
ATC
moxonidine; oral
2.3
6.4
48
216
V03AE01
ATC
polystyrene sulfonate; oral
3.8
6.4
19
51
S43.0
ICD-10 Finland
Dislocation of shoulder joint
2.1
6.4
56
269
SPAT1234
SPAT
Support of social functional capacity
2.0
6.3
62
310
R62.0
ICD-10 Finland
Delayed milestone
3.1
6.3
25
81
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.5
6.3
189
1295
K90.9
ICD-10 Finland
Intestinal malabsorption, unspecified
11.1
6.3
11
10
F40.2
ICD-10 Finland
Specific (isolated) phobias
3.5
6.3
21
61
30180
ICD-8 Finland
Personality disorders, Immatura
9.3
6.3
12
13
F50.0
ICD-10 Finland
Anorexia nervosa
3.3
6.3
23
71
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
18.1
6.3
9
5
Z31.5
ICD-10 Finland
Genetic counselling
1.7
6.3
102
602
F73.0
ICD-10 Finland
Profound mental retardation, with the statement of no, or minimal, impairment of behaviour
+∞
6.3
6
*
34300
ICD-8 Finland
Cerebral spastic infantile paralysis, Hemiplegia spastica
+∞
6.3
6
*
199
Kela drug reimbursment
Rufinamide
+∞
6.3
6
*
3457B
ICD-9 Finland
Epilepsy, Epilepsia partialis continua[EPILEPSIA PARTIALIS CONTINUA]
+∞
6.3
6
*
34533
ICD-8 Finland
Epilepsy, Partialis (focalis) alia
+∞
6.3
6
*
31599
ICD-8 Finland
Unspecified mental retardation, Other and unspecified
+∞
6.3
6
*
AAJ15
NOMESCO Finland
Hippocampectomy
+∞
6.3
6
*
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.7
6.2
112
679
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.9
6.2
74
396
2910A
ICD-9 Finland
Alcoholic psychoses, Alcohol withdrawal delirium
26.8
6.2
8
*
G21.1
ICD-10 Finland
Other drug-induced secondary parkinsonism
26.8
6.2
8
*
C71.20
ICD-10 Finland
Malignant tumor in temporal lobe without histology
26.8
6.2
8
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.8
6.2
88
498
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
2.8
6.2
30
109
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
3.7
6.2
19
52
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
3.1
6.2
25
82
TPH07
NOMESCO Finland
Cathetrisation of artery
1.6
6.2
128
805
N30.9
ICD-10 Finland
Cystitis, unspecified
1.8
6.2
85
477
N05AA01
ATC
chlorpromazine; systemic, rectal
3.2
6.2
23
72
A03FA02
ATC
cisapride; oral, rectal
1.8
6.1
82
456
F81.8
ICD-10 Finland
Other developmental disorders of scholastic skills
7.7
6.1
13
17
L01AX03
ATC
temozolomide; systemic
7.7
6.1
13
17
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.3
6.1
42
182
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
4.1
6.1
16
39
F41.09
ICD-10 Finland
UNS Panic Syndrome
2.0
6.1
61
308
F50.9
ICD-10 Finland
Eating disorder, unspecified
2.8
6.1
29
105
29599
ICD-8 Finland
Schizophrenia, Unspecified type
8.6
6.1
12
14
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
6.0
666
5639
N07BB01
ATC
disulfiram; oral
2.0
6.0
62
316
D10
ICPC
Vomiting
1.6
6.0
129
819
K07
ICPC
Swollen ankles/oedema
2.2
6.0
50
235

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
427
159
34.99
307.65
4.9
5.9
395.23
373.76
umol/l
0.94
393
133
681
3327
2.69
83.72
3.3
2.0
186.53
209.94
u/l
0.42
665
3160
926
5969
2.15
53.70
7.1
7.1
1.21
1.21
mmol/l
2.56
802
5138
847
5364
2.10
50.45
6.4
6.7
1.21
1.22
mmol/l
3.16
799
4947
131
347
4.00
43.94
2.5
2.4
326.11
334.90
ug/l
0.02
123
324
1049
7530
1.95
40.49
6.0
4.8
6.42
6.47
mmol/l
0.37
980
6919
94
270
3.62
27.99
2.8
3.7
35.07
34.13
umol/l
0.17
85
252
516
3382
1.74
22.94
3.9
3.9
7.40
7.40
ph
0.31
93
629
658
4707
1.63
20.51
3.8
3.3
28.99
30.99
u/l
1.00
627
4490
695
5046
1.62
20.35
12.0
11.1
1.14
1.18
inr
0.68
205
1572
923
7176
1.59
20.23
6.4
6.3
0.04
0.04
e9/l
1.56
798
6258
460
3010
1.71
20.16
5.0
4.0
—
—
—
0
0
921
7165
1.59
20.07
6.3
6.3
0.58
0.56
e9/l
1.31
798
6252
700
5112
1.61
19.88
5.0
5.1
35.73
36.54
g/l
3.36
659
4783
233
1240
2.01
19.82
4.1
5.8
1.14
1.66
mmol/l
1.34
191
1014
947
7431
1.58
19.77
6.5
6.3
2.02
2.02
e9/l
0.08
835
6649
886
6847
1.58
19.75
7.0
6.6
8.48
8.26
%
1.26
839
6470
946
7428
1.58
19.64
7.0
6.7
0.17
0.19
e9/l
1.71
832
6586
880
6796
1.58
19.63
6.6
6.4
2.59
2.88
%
3.19
834
6410
220
1152
2.04
19.56
7.6
8.6
1.08
0.94
mmol/l
0.19
176
907
874
6758
1.57
19.25
6.7
6.7
—
—
—
0
0
561
3916
1.63
18.98
2.6
2.5
60.62
58.34
u/l
0.10
525
3660
231
1247
1.98
18.83
4.1
5.8
5.81
5.83
kpa
0.06
216
1211
842
6488
1.56
18.61
5.8
6.0
8.88
11.90
umol/l
8.76
788
6133
218
1159
2.00
18.55
7.5
8.5
5.12
5.12
kpa
0.00
211
1104
218
1160
2.00
18.50
7.5
8.5
13.07
12.68
kpa
0.43
210
1109
1568
14088
1.93
18.32
18.5
12.4
138.68
139.60
mmol/l
25.53
1530
13708
906
7117
1.55
18.24
6.7
6.4
31.35
29.85
%
3.48
860
6745
314
1895
1.80
18.07
3.8
4.5
0.82
0.82
mmol/l
0.35
297
1800
845
6571
1.54
17.57
6.5
6.5
0.63
0.67
%
1.35
799
6187
182
939
2.04
16.78
8.3
9.2
123.24
123.21
g/l
0.01
176
917
887
7016
1.53
16.75
6.4
6.2
53.83
55.61
%
4.17
844
6645
1186
10003
1.55
16.51
7.3
6.9
78.41
79.35
u/l
0.33
1111
9449
1000
8165
1.51
15.90
10.5
9.0
3.88
3.97
e9/l
0.53
870
7139
1559
14132
1.82
15.59
18.2
12.5
3.96
3.94
mmol/l
2.26
1519
13726
577
4214
1.55
15.43
4.0
3.1
28.40
40.64
ng/l
0.94
338
2390
189
1026
1.94
15.05
8.2
9.2
95.60
95.86
%
0.20
182
992
551
4012
1.54
14.82
2.9
3.2
2.34
2.35
mmol/l
2.14
490
3628
503
3632
1.54
13.89
3.4
2.6
—
—
—
0
0
294
1866
1.69
13.89
1.7
1.7
1119.20
1146.56
nmol/l
0.20
232
1448
610
4631
1.48
13.09
1.9
1.8
96.38
96.44
pmol/l
0.01
328
2513
191
1090
1.84
13.01
3.8
5.4
4.87
4.84
kpa
0.06
177
1055
122
606
2.09
12.44
8.8
7.3
24.76
24.37
mmol/l
0.50
116
573
192
1119
1.80
12.20
6.7
9.7
—
—
—
0
0
324
2173
1.60
12.19
4.0
3.3
342.25
542.80
ng/l
0.47
210
1425
173
978
1.85
12.13
4.1
5.9
5.17
5.10
kpa
0.66
167
940
703
5557
1.44
11.93
2.5
2.4
72.67
73.58
nmol/l
0.35
634
5143
129
674
1.99
11.46
4.4
4.9
129.13
129.78
g/l
0.11
121
659
50
171
2.98
11.35
1.5
1.7
69.26
71.33
mmol/l
0.09
38
146
103
498
2.13
11.28
4.3
4.0
24.85
25.20
mmol/l
0.44
97
484
111
553
2.07
11.24
10.1
11.6
—
—
—
0
0
281
1855
1.61
11.23
2.0
2.6
28.99
29.74
s
0.98
271
1802
28
66
4.29
11.03
2.0
3.8
183.07
158.73
umol/l
0.12
14
37
168
969
1.81
11.03
4.2
5.9
7.40
7.41
ph
0.24
13
90
71
303
2.40
10.47
1.5
2.0
—
—
—
0
0
360
2560
1.51
10.27
1.6
1.5
19.96
20.44
nmol/l
0.24
331
2240
1051
9061
1.39
10.15
4.9
3.9
416.00
1927.65
e6/l
1.12
23
115
120
648
1.91
9.70
6.8
5.1
—
—
—
0
0
199
1256
1.66
9.46
2.7
2.4
34.23
77.08
u/l
0.57
180
1061
72
327
2.25
9.24
1.5
1.9
5.09
14.28
e6/l
1.56
56
257
72
327
2.25
9.24
1.5
2.0
881.79
1379.64
e6/l
0.20
61
264
58
241
2.45
9.10
4.4
3.9
2.34
2.33
mmol/l
0.01
40
149
348
2515
1.48
9.07
2.7
2.8
553.65
553.49
mosm/kgh2o
0.00
302
2169
76
359
2.17
8.88
1.2
1.8
539.24
490.42
mg/l
0.18
71
343
74
347
2.18
8.80
8.8
6.4
1.52
1.23
mmol/l
1.45
62
302
420
3167
1.43
8.71
1.7
2.0
1.33
1.01
mg/l
0.47
312
2349
138
809
1.76
8.59
3.8
6.5
23.76
23.79
mmol/l
0.05
131
799
63
281
2.29
8.46
4.2
3.7
7.41
7.42
ph
0.24
56
251
114
634
1.85
8.44
7.8
10.9
1.35
1.39
%
0.18
114
629
170
1062
1.66
8.40
3.8
3.8
—
—
—
0
0
463
3583
1.39
8.21
6.9
6.8
—
—
—
0
0
76
373
2.08
8.07
2.8
1.9
1.08
2.11
ug/l
0.66
67
329
81
408
2.03
8.03
8.1
5.8
0.96
0.90
%
0.68
74
383
54
232
2.37
7.92
10.3
7.8
11.55
11.37
mmol/l
0.10
49
212
87
453
1.97
7.87
2.5
2.9
—
—
—
0
0
54
233
2.36
7.84
10.3
7.7
103.73
105.38
mmol/l
1.30
49
213
81
415
2.00
7.67
7.8
5.7
1.97
1.61
%
1.28
74
388
763
6430
1.33
7.66
9.2
8.8
0.00
0.00
e9/l
0.63
597
5218
124
2014
0.59
7.59
1.3
1.3
—
—
—
0
0
180
1174
1.59
7.49
2.1
2.8
0.23
0.22
g/l
0.34
173
1109
31
104
3.02
7.36
2.8
2.0
—
—
—
0
0
192
1288
1.55
7.07
3.1
3.3
1.76
1.68
%
0.44
168
1169
443
5519
0.74
6.98
2.5
2.4
—
—
—
0
0
483
3848
1.35
6.97
3.0
3.2
63.15
72.08
e6/l
0.10
389
2906
399
3099
1.37
6.75
3.7
3.2
—
—
—
0
0
1599
15171
1.52
6.72
11.4
8.9
28.23
26.73
u/l
0.26
1548
14717
1116
10017
1.30
6.66
3.9
3.0
53.73
41.10
u/l
6.22
1075
9547
235
1681
1.46
6.35
5.7
7.1
1.10
1.10
mmol/l
0.06
218
1583
384
2994
1.36
6.30
4.1
3.5
1.02
1.02
kg/l
0.58
66
426
53
250
2.15
6.30
4.0
3.7
—
—
—
0
0
69
361
1.95
6.22
3.0
2.9
—
—
—
0
0
568
4696
1.31
6.21
3.5
3.7
61.35
83.74
e6/l
0.48
406
3140
48
219
2.22
6.19
2.5
2.3
16.45
16.59
%
0.10
22
122
1530
14496
1.39
5.50
17.0
11.5
21.89
21.54
mg/l
0.16
1260
11170
1065
9617
1.27
5.49
4.7
3.9
—
—
—
0
0
196
1393
1.46
5.47
1.9
2.1
384.75
365.53
nmol/l
0.64
184
1294
415
3337
1.32
5.45
2.2
2.2
2.72
2.79
mg/l
0.29
351
2876
12
17
7.10
5.44
7.7
8.6
—
—
—
0
0
115
731
1.61
5.37
2.7
2.9
—
—
—
0
0
120
772
1.59
5.33
2.6
3.0
107.59
162.19
ng/l
1.59
110
690
407
3289
1.31
5.12
4.5
4.2
95.83
92.52
%
2.16
400
3196
220
1620
1.41
5.06
1.7
1.6
—
—
—
0
0
1268
13518
0.79
4.89
3.9
3.7
1.47
1.45
mmol/l
0.48
1186
12745
50
257
1.97
4.81
2.2
2.3
131.40
132.89
g/l
0.21
40
202
33
144
2.32
4.79
1.9
2.3
—
—
—
0
0
130
877
1.52
4.71
3.7
4.9
82.68
78.11
ng/l
0.20
108
800
1393
13094
1.29
4.70
5.2
4.5
1.87
1.91
mu/l
0.18
1307
12267
145
1002
1.49
4.69
3.0
2.6
4.90
5.60
e9/l
0.26
123
879
1293
13734
0.79
4.68
4.3
4.0
2.81
2.83
mmol/l
0.36
1210
12928
301
2368
1.33
4.56
1.6
1.6
452.20
43053260.69
pmol/l
3.07
255
2044
330
2632
1.31
4.53
2.5
2.6
9.15
6.56
e6/l
1.24
300
2360
150
1052
1.46
4.51
2.2
2.3
7167.06
6366.35
u/l
0.11
66
436
1216
12975
0.80
4.35
3.5
3.4
1.33
1.27
mmol/l
1.98
1134
12197
331
2656
1.30
4.34
2.8
3.1
739.97
1164.09
ng/l
2.40
266
2210
120
814
1.51
4.26
2.0
2.2
—
—
—
0
0
41
206
2.01
4.23
2.6
3.7
—
—
—
0
0
113
759
1.52
4.21
4.8
6.2
—
—
—
0
0
232
1777
1.35
4.20
2.0
2.0
—
—
—
0
0
1284
13590
0.80
4.06
4.0
3.8
4.73
4.71
mmol/l
0.29
1211
12875
124
862
1.47
3.93
1.5
1.4
—
—
—
0
0
129
906
1.46
3.88
2.7
3.2
66.75
70.90
e9/l
0.74
101
660
257
2022
1.32
3.88
2.5
2.9
5.82
2.69
e6/l
1.98
146
1077
60
352
1.73
3.87
4.1
4.1
1.38
1.37
mmol/l
0.05
60
343
128
1785
0.70
3.84
2.6
2.7
0.69
0.75
ug/l
0.34
80
1033
11
24
4.61
3.74
1.6
1.2
—
—
—
0
0
79
505
1.59
3.69
1.1
1.1
2.06
4.68
u/ml
0.80
13
74
75
1153
0.64
3.67
1.3
1.3
—
—
—
0
0
22
91
2.44
3.64
1.2
1.1
—
—
—
0
0
71
444
1.62
3.63
1.7
2.1
1.21
1.39
g/l
0.75
64
397
416
3504
1.24
3.62
2.9
3.1
0.32
0.33
e6/l
0.05
331
2606
246
1945
1.31
3.58
2.3
2.5
13.35
14.16
umol/l
0.93
229
1825
144
1049
1.41
3.57
2.2
2.1
—
—
—
0
0
142
1032
1.41
3.57
2.2
2.0
—
—
—
0
0
143
1041
1.41
3.56
2.2
2.1
—
—
—
0
0
1195
11169
1.21
3.54
4.4
3.9
13.96
14.52
pmol/l
12.12
1112
10358
144
1051
1.40
3.53
2.2
2.1
—
—
—
0
0
1371
12996
1.24
3.52
20.6
14.0
14.14
14.64
%
0.75
1352
12771
227
1785
1.31
3.44
2.3
2.5
2.39
2.41
g/l
0.21
213
1660
134
972
1.41
3.41
2.2
2.1
—
—
—
0
0
12
32
3.77
3.39
10.1
16.8
—
—
—
0
0
492
4248
1.22
3.36
2.5
2.3
—
—
—
0
0
124
892
1.42
3.32
4.1
3.6
1.21
1.23
mmol/l
2.48
113
759
63
393
1.63
3.28
5.7
5.0
—
—
—
0
0
46
265
1.76
3.21
3.9
6.3
—
—
—
0
0
208
1634
1.31
3.19
2.3
2.6
23.46
23.85
%
0.13
163
1422
408
3475
1.23
3.17
2.8
3.1
—
—
—
0
0
30
153
1.98
3.05
1.2
1.5
32.75
111.84
mu/l
0.68
25
134
1081
10084
1.18
2.99
4.1
3.9
10.50
9.97
mm/h
0.63
1012
9430
198
1564
1.30
2.92
1.5
1.4
—
—
—
0
0
115
838
1.40
2.89
4.1
2.5
—
—
—
0
0
9
22
4.11
2.88
1.1
1.8
—
—
—
0
0
31
165
1.89
2.81
1.4
2.6
—
—
—
0
0
243
1983
1.26
2.78
2.5
2.7
2.42
2.43
mmol/l
0.42
213
1734
443
3858
1.20
2.70
1.3
1.4
1.96
1.55
u/ml
0.26
104
1004
18
79
2.29
2.68
1.2
1.3
244110.83
25900.85
e6/l
0.79
12
47
430
3742
1.20
2.64
3.5
3.5
7.73
8.06
mmol/l
0.65
363
3279
110
811
1.38
2.61
1.9
2.2
7.34
7.58
ug/l
0.02
90
726
7
15
4.68
2.59
1.0
1.3
—
—
—
0
0
55
354
1.57
2.58
1.4
1.2
9.22
2.65
u/ml
—
5
30
9
25
3.61
2.57
1.0
1.1
—
—
—
0
0
9
25
3.61
2.57
1.0
1.1
—
—
—
0
0
9
25
3.61
2.57
1.0
1.1
—
—
—
0
0
25
128
1.97
2.55
3.6
2.4
—
—
—
0
0
246
2031
1.25
2.55
1.4
1.4
732.17
485.42
titre
0.69
46
391
30
164
1.84
2.54
2.0
3.7
—
—
—
0
0
27
143
1.90
2.51
7.2
6.0
10.57
10.45
mg/l
0.06
22
130
141
1087
1.32
2.51
7.7
9.3
7.47
8.11
mmol/l
0.61
134
1043
79
554
1.45
2.49
2.3
2.3
—
—
—
0
0
9
26
3.47
2.48
1.4
1.3
—
—
—
0
0
254
2113
1.24
2.46
2.4
2.7
1.11
1.20
e6/l
0.11
142
1160
81
573
1.43
2.44
1.3
1.2
0.20
1.31
u/ml
—
6
49
55
360
1.54
2.42
1.4
1.2
32.12
9.61
u/ml
—
9
53
16
70
2.30
2.41
1.1
1.4
—
—
—
0
0
261
2193
1.22
2.30
1.7
1.6
—
—
—
0
0
25
134
1.88
2.27
1.1
1.2
31.46
40.38
mg/l
0.68
19
106
22
113
1.96
2.25
1.6
1.6
—
—
—
0
0
18
86
2.10
2.23
1.4
2.8
2.45
2.12
u/field
0.14
11
42
25
135
1.86
2.22
1.4
2.3
—
—
—
0
0
65
455
1.44
2.11
1.7
1.6
0.20
0.23
g/l
2.35
56
429
155
1244
1.27
2.08
1.3
1.2
117.83
143.47
iu/ml
0.37
54
486
5
10
5.01
2.07
1.6
1.1
45.98
11.44
nmol/l
—
5
10
130
1638
0.78
2.06
1.2
1.2
—
—
—
0
0
6
15
4.01
2.04
1.0
1.2
—
—
—
0
0
18
90
2.01
2.00
1.1
1.0
—
—
—
0
0
121
946
1.30
2.00
2.5
3.4
4.47
4.66
pmol/l
1.53
107
848
25
141
1.78
1.97
1.5
1.2
—
—
—
0
0
66
473
1.41
1.91
1.6
1.6
1.12
1.18
g/l
0.74
57
444
7
22
3.19
1.88
1.9
1.3
—
—
—
0
0
78
1037
0.74
1.85
1.4
1.6
—
—
—
0
0
132
1056
1.27
1.84
5.3
4.5
0.84
0.95
%
0.24
58
354
932
8778
1.13
1.81
3.3
3.2
—
—
—
0
0
41
271
1.52
1.80
3.9
3.9
—
—
—
0
0
123
982
1.27
1.76
2.3
2.3
21.32
24.92
au/ml
—
6
95
200
1685
1.21
1.75
1.3
1.2
—
—
—
0
0
12
54
2.23
1.74
1.8
1.2
—
—
—
0
0
742
6906
1.13
1.73
3.9
3.3
0.00
0.00
estimate
1.08
159
1372
20
110
1.83
1.73
1.1
1.2
—
—
—
0
0
17
89
1.92
1.70
3.0
3.0
36717.65
41619.10
ug/l
1.14
17
89
52
366
1.43
1.69
1.3
1.4
290.69
309.01
ug/g
0.28
32
203
1562
15256
1.19
1.68
16.0
10.5
—
—
—
0
0
12
55
2.19
1.67
1.7
3.1
—
—
—
0
0
54
384
1.42
1.67
1.3
1.2
—
—
—
0
0
167
1392
1.22
1.64
1.1
1.2
—
—
—
0
0
362
3229
1.15
1.61
2.3
2.2
—
—
—
0
0
12
56
2.15
1.61
1.3
1.4
—
—
—
0
0
16
84
1.91
1.59
1.6
1.2
—
105.80
—
0
5
10
43
2.33
1.58
1.2
1.2
—
—
—
0
0
21
121
1.74
1.58
4.1
3.4
—
—
—
0
0
6
20
3.01
1.58
7.5
11.0
—
—
—
0
0
28
175
1.61
1.58
1.7
1.6
—
—
—
0
0
375
3365
1.14
1.54
1.4
1.5
2.39
2.17
g/l
0.88
215
2084
7
27
2.60
1.51
1.4
1.4
—
—
—
0
0
167
1406
1.21
1.50
1.4
1.5
—
—
—
0
0
212
2450
0.85
1.49
1.5
1.5
—
—
—
0
0
13
65
2.01
1.48
1.1
1.5
147.85
143.91
nmol/l
0.08
13
65
74
567
1.32
1.48
3.2
3.0
—
—
—
0
0
695
6492
1.12
1.47
2.9
2.6
—
—
—
0
0
16
87
1.85
1.46
1.1
1.0
—
—
—
0
0
80
1019
0.77
1.44
1.4
1.4
—
—
—
0
0
18
303
0.59
1.44
1.2
1.3
—
—
—
0
0
38
262
1.46
1.41
1.9
1.6
—
—
—
0
0
37
254
1.47
1.41
1.1
1.3
2.47
4.88
u/ml
1.64
15
117
741
6959
1.11
1.40
3.9
3.3
0.00
0.01
estimate
1.06
145
1280
37
255
1.46
1.39
2.9
3.7
46.19
77.92
mg/l
0.60
29
201
37
255
1.46
1.39
2.9
3.7
31.89
31.58
mg/l
0.02
30
202
12
60
2.01
1.38
1.1
1.2
—
—
—
0
0
5
17
2.95
1.36
2.2
2.5
—
—
—
0
0
15
82
1.84
1.35
2.3
2.5
—
—
—
0
0
76
594
1.29
1.34
2.1
3.3
21.17
21.46
s
0.29
70
532
6
24
2.50
1.30
1.0
1.1
—
—
—
0
0
38
268
1.43
1.28
1.2
1.1
52.00
1708.07
iu/ml
—
8
79
19
114
1.67
1.28
4.6
10.1
11.55
11.47
%
0.03
19
114
9
44
2.05
1.27
1.3
1.3
—
—
—
0
0
23
146
1.58
1.26
4.0
3.7
—
—
—
0
0
608
5679
1.11
1.25
3.2
3.1
6.37
5.88
ph
1.73
35
575
29
195
1.50
1.24
3.0
3.8
—
—
—
0
0
8
36
2.23
1.24
1.6
2.3
—
—
—
0
0
30
204
1.48
1.22
1.2
1.5
—
—
—
0
0
731
6905
1.10
1.19
5.3
4.5
0.00
0.00
estimate
0.50
151
1330
180
1565
1.17
1.16
2.7
3.4
4.90
7.47
umol/l
3.02
147
1333
72
571
1.27
1.16
1.5
1.3
—
—
—
0
0
63
491
1.29
1.16
2.6
4.9
0.28
0.32
g/l
0.25
29
249
17
103
1.66
1.13
1.1
1.0
—
—
—
0
0
25
167
1.50
1.12
1.0
1.2
2.00
4.38
u/ml
—
10
76
106
885
1.21
1.09
1.3
1.2
—
—
—
0
0
5
21
2.38
1.09
1.0
1.0
—
—
—
0
0
119
1006
1.20
1.08
5.6
4.6
0.24
0.12
%
0.47
46
301
95
786
1.22
1.08
2.7
2.8
66.86
66.92
g/l
0.02
90
729
107
896
1.21
1.08
1.2
1.2
—
—
—
0
0
427
3947
1.11
1.07
3.5
2.8
—
—
—
0
0
16
253
0.63
1.05
1.5
1.6
—
—
—
0
0
12
67
1.80
1.04
2.3
3.3
—
—
—
0
0
12
67
1.80
1.04
1.5
4.0
88.80
49.95
umol/l
—
5
13
5
22
2.28
1.03
2.2
2.0
—
—
—
0
0
37
273
1.36
1.01
6.1
3.4
17.74
25.52
mg/l
1.52
26
177
39
291
1.35
1.00
1.1
1.1
2.59
2.27
u/ml
0.15
16
134
20
131
1.53
1.00
1.2
1.4
3.14
3.72
u/ml
0.09
11
77
72
584
1.24
0.99
1.8
1.7
—
—
—
0
0
9
49
1.84
0.98
4.3
2.3
—
—
—
0
0
276
3035
0.89
0.98
3.5
4.2
1.69
2.19
ug/l
1.69
250
2740
7
36
1.95
0.97
6.7
7.6
—
—
—
0
0
331
3039
1.11
0.95
3.7
3.3
800.53
290.54
mg/l
0.79
233
2037
35
259
1.36
0.95
1.1
1.1
—
—
—
0
0
15
93
1.62
0.94
4.7
3.8
—
—
—
0
0
114
976
1.18
0.93
5.2
4.3
0.61
0.66
%
0.10
51
311
19
126
1.51
0.91
1.1
1.0
—
—
—
0
0
13
79
1.65
0.88
32.2
38.7
7.09
7.23
ug/l
0.09
13
71
36
272
1.33
0.87
1.1
1.1
—
—
—
0
0
8
44
1.82
0.86
3.0
2.3
—
—
—
0
0
8
44
1.82
0.86
1.0
1.3
69.50
77.23
nmol/24h
—
8
44
367
3410
1.10
0.84
1.7
1.7
—
—
—
0
0
100
856
1.18
0.83
1.7
1.6
300.12
299.15
mu/l
0.01
89
772
111
959
1.17
0.83
5.7
4.6
0.11
0.77
%
0.82
38
255
18
121
1.49
0.82
2.2
1.7
55.00
58.69
%
0.16
12
86
27
197
1.38
0.82
1.1
1.4
—
—
—
0
0
500
5295
0.92
0.82
1.9
2.0
—
—
—
0
0
43
338
1.28
0.80
1.3
1.4
—
6.50
—
0
5
8
47
1.71
0.80
1.0
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.0
—
—
—
0
0
154
1373
1.13
0.76
4.0
3.8
32.27
31.35
%
0.45
113
1010
9
53
1.70
0.75
3.4
2.7
2.70
2.70
mmol/l
—
9
48
14
91
1.54
0.75
1.1
1.4
—
—
—
0
0
5
24
2.09
0.74
1.0
1.9
—
—
—
0
0
342
3189
1.09
0.73
4.2
3.9
14.43
15.29
mg/mmol
0.05
239
2108
10
60
1.67
0.72
1.2
1.3
—
—
—
0
0
6
110
0.54
0.72
1.3
1.4
185.50
163.89
pmol/l
—
6
110
30
229
1.32
0.71
1.8
1.4
—
—
—
0
0
43
346
1.25
0.69
1.1
1.3
—
—
—
0
0
17
118
1.44
0.69
1.8
2.0
—
—
—
0
0
16
110
1.46
0.68
2.9
2.0
—
—
—
0
0
135
1505
0.89
0.65
1.5
1.4
—
—
—
0
0
54
645
0.83
0.65
1.3
1.5
—
—
—
0
0
17
120
1.42
0.64
3.2
2.0
33.88
32.50
pg
0.85
17
120
22
163
1.35
0.64
1.2
1.3
0.55
0.58
nmol/l
0.21
22
155
125
1115
1.13
0.64
3.1
2.8
10.98
10.27
g/l
1.07
117
1037
358
3367
1.08
0.63
1.7
1.7
1.43
1.39
mmol/l
0.29
317
2917
10
63
1.59
0.61
1.1
1.4
0.14
2.04
u/ml
—
10
63
39
316
1.24
0.61
1.1
1.1
0.16
0.35
u/ml
0.74
12
110
0
21
0.00
0.60
0.0
1.2
—
19.60
—
0
5
0
21
0.00
0.60
0.0
1.2
—
32.20
—
0
5
384
3633
1.07
0.59
4.3
3.5
0.00
0.01
estimate
1.49
146
1292
29
228
1.28
0.58
3.0
3.2
—
—
—
0
0
122
1095
1.12
0.58
1.4
1.3
147.93
241.77
u/ml
1.23
105
1014
12
81
1.48
0.57
2.4
1.6
37.29
32.52
%
—
7
52
8
55
1.46
0.56
1.1
1.3
—
—
—
0
0
20
150
1.34
0.56
1.2
1.3
—
—
nmol/l
—
0
0
11
160
0.69
0.55
1.1
1.2
—
—
—
0
0
25
195
1.29
0.54
1.2
1.2
—
—
—
0
0
261
2444
1.08
0.53
1.3
1.3
25.68
25.86
iu/ml
0.01
88
756
57
663
0.86
0.53
1.3
1.5
—
—
—
0
0
34
277
1.23
0.52
1.4
1.3
15.20
19.52
u/l
0.48
25
240
28
223
1.26
0.52
1.4
1.9
4.20
5.22
mmol/24h
0.87
20
200
333
3151
1.07
0.52
3.6
3.3
—
—
—
0
0
33
269
1.23
0.51
5.8
4.4
57.18
55.94
%
0.18
33
269
56
649
0.86
0.51
1.3
1.5
—
—
—
0
0
106
955
1.12
0.49
3.1
3.2
—
—
—
0
0
53
456
1.17
0.48
1.2
1.2
—
—
—
0
0
16
119
1.35
0.48
1.0
1.4
1.94
1.44
nmol/l
1.48
16
110
111
1006
1.11
0.47
1.4
1.5
25.09
23.17
iu/l
0.27
96
822
133
1217
1.10
0.47
3.6
3.4
—
—
—
0
0
32
386
0.83
0.46
2.5
3.5
92.84
3671.44
u/ml
0.77
25
329
75
665
1.13
0.46
1.4
1.5
8.13
8.50
u/l
0.10
62
530
59
674
0.87
0.46
1.1
1.1
—
—
—
0
0
5
83
0.60
0.45
6.8
7.0
—
—
—
0
0
446
4646
0.95
0.45
1.6
1.6
—
—
—
0
0
20
156
1.29
0.45
1.4
1.3
9.15
6.31
g/l
1.10
14
113
20
156
1.29
0.45
1.4
1.3
2.83
2.75
g/l
0.09
14
111
20
156
1.29
0.45
1.4
1.3
0.35
0.40
g/l
0.36
14
111
26
210
1.24
0.45
2.3
2.5
—
—
—
0
0
7
50
1.40
0.45
1.9
3.4
—
—
—
0
0
15
112
1.34
0.44
2.1
3.0
1.16
1.66
g/24h
—
7
65
42
358
1.18
0.44
1.9
3.1
5.03
7.06
umol/l
0.74
33
271
42
358
1.18
0.44
1.4
1.6
—
—
—
0
0
6
92
0.65
0.42
1.2
1.1
—
1.38
—
0
16
40
341
1.18
0.42
1.4
1.6
80.30
97.52
u/ml
—
6
62
19
149
1.28
0.42
1.0
1.1
0.07
5.02
u/ml
—
6
54
20
158
1.27
0.41
1.4
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
2.8
—
4132.21
—
0
19
0
19
0.00
0.39
0.0
1.2
—
57.90
—
0
5
22
269
0.82
0.38
1.3
1.1
—
—
—
0
0
55
486
1.14
0.38
1.1
1.1
5.90
6.44
u/ml
0.08
26
293
31
262
1.19
0.37
5.7
4.0
4.25
4.07
e9/l
0.14
31
262
5
76
0.66
0.35
2.4
4.2
—
34.40
—
0
13
13
99
1.32
0.35
1.1
1.2
1.16
1.05
ratio
—
5
43
13
99
1.32
0.35
1.3
1.2
—
—
—
0
0
6
45
1.33
0.33
2.5
2.2
11.95
1.94
ug/l
—
6
38
254
2657
0.95
0.32
1.8
1.7
—
—
—
0
0
56
505
1.11
0.30
1.3
1.2
—
—
—
0
0
14
111
1.26
0.30
1.1
1.2
—
—
—
0
0
7
57
1.23
0.29
1.4
1.4
—
—
—
0
0
68
623
1.10
0.28
2.5
2.4
—
—
—
0
0
15
183
0.82
0.27
2.0
1.4
—
—
—
0
0
328
3172
1.04
0.26
2.5
2.6
7748.77
5097.05
umol/l
0.35
286
2863
10
77
1.30
0.26
1.1
1.1
1413.80
1565.53
miu/ml
—
10
77
5
75
0.67
0.25
1.2
1.9
—
—
—
0
0
11
138
0.80
0.25
1.0
1.1
—
—
—
0
0
40
358
1.12
0.25
1.1
1.1
4.93
6.30
u/ml
0.13
24
183
241
2318
1.05
0.25
1.3
1.3
9.14
10.23
u/ml
0.11
79
948
18
151
1.19
0.25
1.1
1.3
—
—
—
0
0
20
170
1.18
0.24
1.9
1.8
—
—
—
0
0
12
96
1.25
0.24
1.1
1.2
—
—
—
0
0
1309
13204
0.97
0.24
22.1
14.5
334.66
333.43
g/l
5.06
1303
13095
14
115
1.22
0.23
1.2
1.2
—
—
—
0
0
20
171
1.17
0.23
3.3
4.1
5102.15
309.06
u/ml
0.45
20
161
37
332
1.12
0.23
1.1
1.1
6.60
6.91
u/ml
0.02
16
143
44
400
1.10
0.22
1.7
2.0
3.03
4.85
iu/l
2.70
13
156
5
40
1.25
0.22
1.2
1.2
—
—
—
0
0
20
172
1.16
0.22
1.1
1.3
0.94
4.00
u/ml
—
6
71
51
468
1.09
0.22
1.1
1.1
0.45
1.27
u/ml
1.48
23
235
5
42
1.19
0.21
1.0
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
162.09
—
0
11
0
11
0.00
0.21
0.0
2.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
177
1843
0.96
0.21
1.7
1.9
—
—
—
0
0
33
296
1.12
0.21
1.3
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.6
—
11.00
—
0
7
28
249
1.13
0.20
1.3
1.7
1.08
0.81
g/l
0.19
20
192
6
48
1.25
0.20
1.2
1.9
—
—
—
0
0
36
326
1.11
0.20
2.1
2.2
—
—
—
0
0
9
111
0.81
0.20
1.2
1.2
—
—
—
0
0
17
197
0.86
0.19
1.0
1.1
—
—
—
0
0
67
716
0.93
0.19
1.4
1.3
293.78
225.64
miu/ml
0.81
31
359
11
90
1.22
0.19
1.3
1.2
—
—
—
0
0
30
270
1.11
0.19
1.9
1.7
5812.36
12678.34
e6/l
1.50
22
199
53
492
1.08
0.18
1.2
1.1
—
—
—
0
0
15
128
1.17
0.18
2.9
3.4
—
—
—
0
0
430
4213
1.03
0.18
2.2
2.0
—
—
—
0
0
7
59
1.19
0.18
4.1
4.2
—
—
—
0
0
35
383
0.91
0.18
1.1
1.1
—
—
—
0
0
35
383
0.91
0.18
1.1
1.1
—
—
—
0
0
706
6962
1.02
0.17
3.0
2.9
112.01
93.74
ug/l
0.82
659
6569
13
111
1.17
0.15
2.2
1.5
—
—
—
0
0
6
80
0.75
0.15
1.3
1.1
111.67
205.66
iu/ml
—
6
80
9
81
1.11
0.15
1.1
1.2
—
—
—
0
0
9
83
1.08
0.14
2.7
1.4
8.33
7.24
u/l
—
9
68
11
93
1.18
0.14
1.5
1.5
—
—
—
0
0
49
461
1.06
0.13
1.2
1.1
3.04
2.18
u/ml
0.14
24
263
15
132
1.14
0.13
1.8
3.0
0.16
0.20
e9/l
—
9
110
78
746
1.05
0.13
1.4
1.4
—
—
—
0
0
24
262
0.91
0.12
2.0
1.7
—
—
—
0
0
73
699
1.05
0.12
1.0
1.1
—
—
—
0
0
1642
16460
0.97
0.11
25.4
16.9
249.59
257.32
e9/l
5.50
1605
16070
138
1418
0.97
0.10
1.3
1.3
—
—
—
0
0
37
348
1.06
0.10
1.8
2.5
—
—
—
0
0
1644
16477
0.97
0.10
25.3
16.9
6.72
6.76
e9/l
0.19
1604
16053
11
96
1.15
0.10
1.3
1.1
—
—
—
0
0
1644
16476
0.97
0.10
25.2
16.8
30.31
30.06
pg
6.91
1631
16282
1200
11941
1.02
0.10
5.4
4.7
38.63
38.57
mmol/mol
0.07
1116
11268
1645
16485
0.97
0.10
25.5
17.0
134.37
136.35
g/l
7.16
1630
16289
15
135
1.11
0.09
1.3
1.4
—
—
—
0
0
15
135
1.11
0.09
1.9
2.9
330.44
509.13
e6/l
—
9
110
44
418
1.05
0.09
1.3
1.5
269.96
224.05
u/ml
0.39
23
242
10
114
0.88
0.09
2.0
1.6
—
—
—
0
0
5
47
1.06
0.09
1.0
1.5
—
—
—
0
0
108
1111
0.97
0.09
2.6
2.2
10.50
12.47
nmol/l
1.76
93
1015
5
48
1.04
0.09
1.0
1.1
—
—
—
0
0
1295
13001
0.99
0.09
4.1
3.7
5.80
5.76
mmol/l
0.48
1204
12074
11
97
1.13
0.09
3.0
2.6
—
—
—
0
0
1644
16472
0.98
0.08
25.2
16.8
90.35
89.93
fl
3.10
1631
16280
6
56
1.07
0.08
1.3
2.7
—
—
—
0
0
1645
16477
0.98
0.07
25.3
16.9
4.46
4.56
e12/l
14.04
1607
16061
11
120
0.92
0.05
1.0
1.6
9.62
11.50
umol/l
0.45
11
111
34
353
0.96
0.04
1.3
1.5
0.31
0.43
nmol/l
0.44
28
291
26
272
0.96
0.04
1.2
1.2
—
—
—
0
0
14
150
0.93
0.04
1.3
1.4
29.24
33.86
nmol/l
0.21
14
133
214
2120
1.01
0.04
2.1
2.7
102.35
110.79
ug/g
0.17
163
1703
30
289
1.04
0.04
1.0
1.1
—
—
—
0
0
25
260
0.96
0.03
2.6
2.3
75.42
111.80
ug/min
0.26
14
166
42
409
1.03
0.03
9.3
8.8
—
—
—
0
0
88
867
1.02
0.03
1.6
1.8
1.52
1.29
g/l
0.48
80
811
33
320
1.03
0.03
2.6
2.4
0.97
0.79
nmol/l
0.68
28
277
21
201
1.05
0.03
2.0
1.7
—
—
—
0
0
10
107
0.93
0.02
1.2
1.2
—
—
—
0
0
12
126
0.95
0.00
1.0
1.0
—
—
—
0
0
14
146
0.96
0.00
1.2
1.2
—
—
—
0
0
53
524
1.01
0.00
1.2
1.2
2.99
2.77
u/ml
0.06
26
296
99
984
1.01
0.00
4.2
4.3
15.50
23.11
ug/l
0.30
82
784
56
564
0.99
0.00
1.6
1.7
—
—
—
0
0
1645
16452
1.00
0.00
25.3
17.0
39.44
40.74
%
3.99
1536
15605
10
103
0.97
0.00
1.4
1.4
66.10
75.85
umol/l
—
10
103
0
5
0.00
0.00
0.0
1.2
—
1300.40
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
0.00
2.2
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
8.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.4
—
0.44
—
0
5
0
5
0.00
0.00
0.0
1.0
—
2.57
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
-0.00
1.0
1.0
—
—
—
0
0
6
69
0.87
-0.00
4.2
2.8
—
—
—
0
0
8
88
0.91
-0.00
2.4
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
93
0.97
-0.00
1.0
1.0
7.35
8.95
mu/l
—
9
85
5
52
0.96
-0.00
1.2
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
-0.00
1.2
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
188.57
—
0
7
6
69
0.87
-0.00
8.3
5.5
—
—
—
0
0
8
81
0.99
-0.00
1.5
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint GE and mortality.

Females

Parameter HR [95% CI] p-value
GE 3.087 [2.71, 3.52] < 0.001
Birth year 0.994 [0.99, 1.0] 0.17

During the follow-up period (1.1.1998 — 31.12.2019), 687 out of 6796 females with GE died.

Males

Parameter HR [95% CI] p-value
GE 2.745 [2.43, 3.11] < 0.001
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 870 out of 5793 males with GE died.

Mortality risk

Mortality risk for people of age

years, who have GE.

N-year risk Females Males
1 0.297% 0.461%
5 1.675% 3.273%
10 4.035% 7.686%
15 8.089% 14.45%
20 13.76% 22.713%

Relationships between endpoints

Index endpoint: GE – Generalized epilepsy

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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