generalised epilepsy: A chronic condition characterised by recurrent generalised seizures.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1762 |
4. Check minimum number of eventsNone |
1762 |
5. Include endpointsNone |
1762 |
6. Filter based on genotype QC (FinnGen only) |
1762 |
Control definitions (FinnGen only)
- Control exclude
- G6_EPLEPSY
Extra metadata
- First used in FinnGen datafreeze
- DF3
Similar endpoints
↥List of similar endpoints to
Generalized epilepsy
based on the number of shared cases.
Similar with more cases:
- Episodal and paroxysmal disorders
- Neurological diseases
- Neurological diseases, wide definition
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 23791 | 11883 | 11645 |
| Only index persons | 18264 | 9848 | 8416 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.33 | 0.34 | 0.33 |
| Only index persons | 0.34 | 0.36 | 0.32 |
| Median age at first event (years) | |||
| Whole population | 27.14 | 24.77 | 28.84 |
| Only index persons | 22.12 | 22.16 | 22.08 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1762 | 1061 | 701 |
| Unadjusted period prevalence (%) | 0.34 | 0.36 | 0.31 |
| Median age at first event (years) | 27.25 | 24.35 | 31.64 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1615
- Matched controls
- 16149
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G40.9
ICD-10 Finland
Epilepsy, unspecified
8446.9
323.0
868
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
33.8
323.0
525
227
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
+∞
323.0
1421
*
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
+∞
323.0
324
*
N03AF02
ATC
oxcarbazepine; oral
99.4
323.0
437
60
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
+∞
323.0
318
*
N03AX14
ATC
levetiracetam; systemic
282.4
323.0
464
23
183
Kela drug reimbursment
Lamotrigin and topiramate
+∞
323.0
443
*
G40.39
ICD-10 Finland
Other or unspecified generalized epileptic syndromes with atonic, clonic, myoclonic or tonic-clonic seizures
+∞
323.0
771
*
N03AG01
ATC
valproic acid; systemic, rectal
60.9
323.0
927
349
3451A
ICD-9 Finland
Epilepsy, Generalised convulsive epilepsy
+∞
323.0
353
*
G40.3
ICD-10 Finland
Generalized idiopathic epilepsy and epileptic syndromes
+∞
323.0
329
*
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
+∞
323.0
470
*
N03AF01
ATC
carbamazepine; oral, rectal
40.4
323.0
534
195
G40.30
ICD-10 Finland
Benign myoclonic eplilepsy in infancy
+∞
315.2
292
*
N03AX09
ATC
lamotrigine; oral
17.9
285.3
471
363
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
+∞
278.4
259
*
G40
ICD-10 Finland
Epilepsy
2702.3
258.3
243
*
N05BA01
ATC
diazepam; systemic, rectal
9.2
231.0
548
856
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
2185.1
192.6
183
*
N05BA09
ATC
clobazam; oral
667.8
184.6
179
*
N88
ICPC
Epilepsy
+∞
183.9
173
*
G40.36
ICD-10 Finland
Juvenile myoclonic epilepsy [impulsive petit mal]
+∞
178.5
168
*
G40.6
ICD-10 Finland
Grand mal seizures, unspecified (with or without petit mal)
+∞
174.2
164
*
N03AB02
ATC
phenytoin; systemic
163.5
155.5
162
11
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
+∞
137.5
130
*
G40.89
ICD-10 Finland
Other epilepsy
+∞
131.0
124
*
G40.10
ICD-10 Finland
Simple partial seizures
+∞
127.8
121
*
3459X
ICD-9 Finland
Epilepsy, unspecified
+∞
124.6
118
*
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
+∞
124.6
118
*
34599
ICD-8 Finland
Epilepsy, Other and unspecified
+∞
116.0
110
*
34519
ICD-8 Finland
Epilepsy, Generalisata convulsiva NUD
+∞
112.8
107
*
7803A
ICD-9 Finland
General symptoms, Convulsions
38.1
111.8
143
41
N03AE01
ATC
clonazepam; systemic
8.7
110.6
255
342
G40.09
ICD-10 Finland
Other or unspecified partial (focal) idiopathic epilepsy or epileptic syndrome with local onset
+∞
105.4
100
*
N03AX18
ATC
lacosamide; systemic
366.8
104.5
104
*
N03AX11
ATC
topiramate; oral
12.7
103.5
192
170
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
+∞
90.5
86
*
G40.00
ICD-10 Finland
Benign childhood epilepsy with centrotemporal EEG spikes
+∞
87.3
83
*
3454A
ICD-9 Finland
Epilepsy, Partial epilepsy, with impairment of consciousness[EPILEPSIA GENERALISATA SECUNDARIA]
+∞
87.3
83
*
3450A
ICD-9 Finland
Epilepsy, Generalised nonconvulsive epilepsy
+∞
86.2
82
*
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
13.4
84.2
151
123
G40.35
ICD-10 Finland
Juvenile absence epilepsy
+∞
84.1
80
*
34510
ICD-8 Finland
Epilepsy, """"Grand mal""""
+∞
84.1
80
*
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
+∞
80.9
77
*
3453A
ICD-9 Finland
Epilepsy, Grand mal status
+∞
79.8
76
*
G40.1
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
+∞
76.7
73
*
G40.33
ICD-10 Finland
Juvenile absence epilepsy
+∞
75.6
72
*
N03AD01
ATC
ethosuximide; oral
+∞
70.3
67
*
N05CD08
ATC
midazolam; nasal, systemic
14.8
70.2
120
87
78020
ICD-8 Finland
Certain symptoms referable to nervous system and special senses, Convulsions
21.3
68.3
102
51
G41.9
ICD-10 Finland
Status epilepticus, unspecified
125.5
67.4
72
6
N03AX22
ATC
perampanel; oral
610.0
60.1
59
*
N03AG04
ATC
vigabatrin; oral
+∞
57.6
55
*
AA1AD
NOMESCO Finland
CT of head and brain
2.9
54.3
391
1595
N03AX15
ATC
zonisamide; oral
69.1
52.5
60
9
XA800
NOMESCO Finland
Neuropsychological investigation
5.7
49.5
150
285
181
Kela drug reimbursment
Retigabine and vigabatrin
+∞
42.9
41
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.7
42.2
200
593
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.7
42.1
197
578
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
9.3
41.8
89
101
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.6
39.6
190
569
N03AX23
ATC
brivaracetam; systemic
+∞
37.6
36
*
XA400
NOMESCO Finland
EEG
23.2
37.6
54
24
3454B
ICD-9 Finland
Epilepsy, Partial epilepsy, with impairment of consciousness[TEMPORAALIEPILEPTINEN POISSAOLOKOHTAUS]
+∞
36.6
35
*
N05AX08
ATC
risperidone; systemic
3.6
36.3
177
536
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.5
36.2
186
586
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.4
35.6
355
1698
G40.0
ICD-10 Finland
Localization-related (focal)(partial) idiopathic epilepsy and epileptic syndromes with seizures of localized onset
+∞
35.5
34
*
34532
ICD-8 Finland
Epilepsy, Partialis (focalis) generalisata
+∞
35.5
34
*
ADB00
NOMESCO Finland
Implantation of vagus nerve stimulating device
+∞
31.3
30
*
G41.0
ICD-10 Finland
Grand mal status epilepticus
163.1
30.8
32
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.6
30.6
244
1024
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.8
30.4
138
392
F02.89*G40.9
ICD-10 Finland
Dementia in epilepsy
+∞
30.3
29
*
R55
ICD-10 Finland
Syncope and collapse
3.0
29.5
181
643
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.8
29.4
207
808
G40.11
ICD-10 Finland
Simple partial epileptic seizure that develops into a complex partial seizure
+∞
29.2
28
*
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
9.1
27.3
58
66
N05AA02
ATC
levomepromazine; systemic
4.5
27.3
101
238
N03AF04
ATC
eslicarbazepine; oral
+∞
27.2
26
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.0
26.3
426
2479
34500
ICD-8 Finland
Epilepsy, """"Petit mal""""
+∞
26.1
25
*
N05AD01
ATC
haloperidol; systemic
5.4
25.5
78
150
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
9.9
25.3
51
53
N05AH03
ATC
olanzapine; systemic
3.1
24.6
142
486
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.2
24.5
135
446
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.4
24.5
126
396
F29
ICD-10 Finland
Unspecified nonorganic psychosis
3.9
24.2
103
277
34530
ICD-8 Finland
Epilepsy, Psychomotorica
+∞
24.0
23
*
N05AH04
ATC
quetiapine; oral
2.1
23.9
305
1604
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
23.7
337
1851
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
5.0
23.3
76
157
N07
ICPC
Convulsion/seizure
40.7
22.7
28
7
G40.7
ICD-10 Finland
Petit mal, unspecified, without grand mal seizures
233.1
22.7
23
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.2
22.5
249
1226
G40.8
ICD-10 Finland
Other epilepsy
+∞
21.9
21
*
G40.34
ICD-10 Finland
Epilepsy with grand mal seizures on awakening
+∞
21.9
21
*
A06AD11
ATC
lactulose; oral
2.4
21.1
188
833
3454X
ICD-9 Finland
Epilepsy, Partial epilepsy, with impairment of consciousness[ALII DISTURBATIONES CONSCIENTAE EPILEPTICI]
+∞
20.9
20
*
G40.80
ICD-10 Finland
Epilepsy with continuous EEG spike-waves during slow wave sleep
+∞
20.9
20
*
34598
ICD-8 Finland
Epilepsy, Alia definita
+∞
20.9
20
*
G40.31
ICD-10 Finland
Benign neonatal convulsions (familial)
+∞
20.9
20
*
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
20.6
242
1220
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.7
20.2
143
558
R56.0
ICD-10 Finland
Febrile convulsions
10.8
19.9
38
36
R53
ICD-10 Finland
Malaise and fatigue
1.9
19.8
315
1793
F20.9
ICD-10 Finland
Schizophrenia, unspecified
5.5
19.8
59
111
N05CD07
ATC
temazepam; oral
2.5
19.2
161
688
N06AB04
ATC
citalopram; systemic
1.9
19.0
328
1923
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
19.0
302
1717
W19
ICD-10 Finland
Unspecified fall
2.4
18.6
168
746
N03AG06
ATC
tiagabine; oral
192.1
18.6
19
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.7
18.4
128
492
R11
ICD-10 Finland
Nausea and vomiting
2.6
18.2
140
570
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.0
18.0
105
362
N05BA04
ATC
oxazepam; oral
1.8
17.5
357
2204
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.6
17.5
136
557
R51.80
ICD-10 Finland
Headache
1.9
17.4
270
1517
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.0
17.3
244
1324
N05AH02
ATC
clozapine; systemic
4.8
17.2
57
121
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.1
17.1
197
984
N03AA02
ATC
phenobarbital; systemic
50.6
17.0
20
*
G41.2
ICD-10 Finland
Complex partial status epilepticus
+∞
16.7
16
*
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
5.1
16.6
52
104
F44.5
ICD-10 Finland
Dissociative convulsions
91.0
16.6
18
*
R42
ICD-10 Finland
Dizziness and giddiness
1.9
16.2
280
1630
N05AF03
ATC
chlorprothixene; systemic
4.2
15.9
60
146
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
15.7
294
1761
G40.59
ICD-10 Finland
Other special epileptic syndromes
+∞
15.6
15
*
G40.37
ICD-10 Finland
Baltic myoclonus
+∞
15.6
15
*
N05AB03
ATC
perphenazine; systemic, rectal
3.6
15.4
70
201
S06.0
ICD-10 Finland
Concussion
2.1
15.2
183
930
A28
ICPC
Limited function/disability NOS
2.2
15.1
160
767
3452A
ICD-9 Finland
Epilepsy, Petit mal status
+∞
14.6
14
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.6
14.5
111
450
V700A
ICD-9 Finland
General medical examination, Routine general medical examination at a health care facility
4.2
14.4
55
136
4380A
ICD-9 Finland
Late effects of cerebrovascular disease[SEQUELAE MORBI CEREBROVASCULARIS]
17.1
14.3
22
13
AEA50
NOMESCO Finland
Adjustment of implanted neurostimulator
19.3
14.2
21
11
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
13.5
14.2
24
18
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.0
14.1
81
277
C03CA01
ATC
furosemide; systemic
1.8
14.0
270
1626
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
14.0
520
3763
N05CD02
ATC
nitrazepam; oral
6.4
14.0
36
57
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
17.7
13.8
21
12
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
20.2
13.8
20
10
N05AC02
ATC
thioridazine; oral
4.7
13.7
46
100
7802X
ICD-9 Finland
General symptoms, Syncope and collapse[SYNCOPE ET COLLAPSUS NUD]
16.4
13.5
21
13
WX892
NOMESCO Finland
Monitored bed care
2.4
13.4
111
473
N04AA02
ATC
biperiden; systemic
4.6
13.1
45
101
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.1
12.8
144
709
G41.1
ICD-10 Finland
Petit mal status epilepticus
70.4
12.6
14
*
113
Kela drug reimbursment
Anxiety disorders associated with mental retardation
17.5
12.5
19
11
34539
ICD-8 Finland
Epilepsy, Partialis (focalis) NUD
+∞
12.5
12
*
Y0209
ICD-8 Finland
Examination of the nervous system and sensory organs, Nervous system
9.4
12.5
25
27
M79.6
ICD-10 Finland
Pain in limb
1.5
12.4
474
3430
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.5
12.4
98
405
TAB00
NOMESCO Finland
Lumbar puncture
2.7
12.3
85
327
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.9
12.2
75
267
AA1BD
NOMESCO Finland
Extensive CT of head and brain
4.7
12.2
40
86
L17
ICPC
Foot/toe symptom/complaint
1.6
12.1
341
2289
4300A
ICD-9 Finland
Subarachnoid haemorrhage[HAEMORRHAGIA SUBARACHNOID. POST ANEURYSMA SACCULARE]
18.2
12.0
18
10
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
12.0
523
3892
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.3
12.0
110
491
R40.2
ICD-10 Finland
Coma, unspecified
9.7
11.7
23
24
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
11.6
244
1505
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
3.9
11.6
47
124
N05AX12
ATC
aripiprazole; systemic
2.6
11.5
86
346
AAA35
NOMESCO Finland
Insertion of subdural electrodes
+∞
11.5
11
*
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
4.1
11.4
43
106
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.1
11.1
121
587
S01.0
ICD-10 Finland
Open wound of scalp
2.4
11.1
96
418
N05CF01
ATC
zopiclone; oral
1.6
11.0
368
2572
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
3.4
10.9
51
152
P29
ICPC
Psychological sympt/compl other
2.2
10.8
115
553
T90.5
ICD-10 Finland
Sequelae of intracranial injury
6.8
10.7
26
39
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
3.8
10.6
44
119
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
5.4
10.4
30
56
C71.10
ICD-10 Finland
Malignant tumor in frontal lobe without histology
110.7
10.4
11
*
N02BE01
ATC
paracetamol; systemic, rectal
1.5
10.4
1204
10755
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
10.4
272
1782
A46
ICD-10 Finland
Erysipelas
1.9
10.4
155
855
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.1
10.3
55
181
3050A
ICD-9 Finland
Nondependent abuse of drugs, Alcohol abuse
8.2
10.3
22
27
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
10.2
326
2245
AA5DR
NOMESCO Finland
Brain metabolism PET with CT
23.5
10.2
14
6
A04
ICPC
Weakness/tiredness general
1.8
10.2
191
1136
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
4.9
10.2
32
66
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
10.1
145
785
N01
ICPC
Headache
1.7
10.1
208
1275
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.9
10.0
150
826
L03
ICPC
Low back symptom/complaint
1.6
10.0
326
2258
P99
ICPC
Psychological disorders other
3.0
9.9
57
196
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
20.2
9.8
14
7
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
4.3
9.8
35
83
P72
ICPC
Schizophrenia
3.9
9.7
38
98
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
7.4
9.7
22
30
E950A
ICD-9 Finland
Suicide and self-inflicted poisoning by solid or liquid substances
6.2
9.7
25
41
6489X
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Other current conditions classifiable elsewhere
13.4
9.7
16
12
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.8
9.6
170
992
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
9.5
469
3551
C71.11
ICD-10 Finland
Malignant tumor of frontal lobe grade II glioma
100.6
9.4
10
*
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
4.6
9.4
31
68
3458X
ICD-9 Finland
Epilepsy, Other forms of epilepsy
+∞
9.4
9
*
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
12.4
9.4
16
13
SPAT1254
SPAT
Administration of medicine
1.7
9.3
207
1297
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.3
9.2
81
358
F70.9
ICD-10 Finland
Mild mental retardation, Without mention of impairment of behaviour
13.7
9.2
15
11
H03AA01
ATC
levothyroxine sodium; systemic
1.6
9.1
287
1967
SPAT1240
SPAT
Therapeutic discussion
1.7
9.1
192
1184
N06AX16
ATC
venlafaxine; oral
1.7
9.0
201
1256
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
9.0
149
851
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
9.0
170
1015
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
9.0
218
1400
N03AA03
ATC
primidone; oral
18.7
8.9
13
7
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
4.1
8.9
33
82
F83
ICD-10 Finland
Mixed specific developmental disorders
4.5
8.9
30
68
L28
ICPC
Limited function/disability (L)
1.8
8.8
162
958
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
8.8
249
1660
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
2.5
8.7
66
269
2402
FHL
External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)
5.1
8.6
26
52
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
5.8
8.6
23
40
SPAT1301
SPAT
No procedures
1.4
8.6
422
3179
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.7
8.5
174
1061
SPAT1229
SPAT
Assessment of need for aid
2.2
8.5
85
401
J01DA01
ATC
[U] cefalexin; systemic
1.4
8.5
877
7518
F71.0
ICD-10 Finland
Moderate mental retardation, with the statement of no, or minimal, impairment of behaviour
20.1
8.5
12
6
78159
ICD-8 Finland
Other symptoms referable to nervous system and special senses, Laesio loquendi alia sive NUD
20.1
8.5
12
6
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
20.1
8.5
12
6
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.8
8.4
149
871
34520
ICD-8 Finland
Epilepsy, Status epilepticus
+∞
8.3
8
*
96698
ICD-8 Finland
Other antiepileptics
+∞
8.3
8
*
3456B
ICD-9 Finland
Epilepsy, Infantile spasms[EPILEPSIA MYOCLONICA CUM ASTASIA]
+∞
8.3
8
*
G40.50
ICD-10 Finland
Epilepsia partialis continua [Kozhevnikof]
+∞
8.3
8
*
AAJ99
NOMESCO Finland
Other operation for epilepsy
+∞
8.3
8
*
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
3.2
8.3
42
135
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
7.1
8.3
19
27
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
8.2
447
3430
N03AX12
ATC
gabapentin; oral
1.7
8.2
184
1152
J01EA01
ATC
trimethoprim; systemic
1.5
8.2
322
2312
G44.2
ICD-10 Finland
Tension-type headache
1.7
8.2
185
1165
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
17.3
8.1
12
7
N05AF05
ATC
zuclopenthixol; systemic
4.9
8.1
25
52
E883A
ICD-9 Finland
Fall into hole or other opening in surface
2.5
8.1
60
245
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
8.1
320
2306
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
8.0
121
673
N06AX11
ATC
mirtazapine; oral
1.4
8.0
397
2990
9694A
ICD-9 Finland
Poisoning by psychotropic agents, Benzodiazepine-based tranquillisers
7.3
8.0
18
25
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
3.7
8.0
33
91
RS221
NOMESCO Finland
NA
3.8
8.0
32
86
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.2
7.9
76
353
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
3.6
7.9
34
97
30188
ICD-8 Finland
Personality disorders, Alia definita
13.1
7.9
13
10
SPAT1210
SPAT
Application of cast or individual aid
2.4
7.8
64
274
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
2.9
7.8
45
157
S30.0
ICD-10 Finland
Contusion of lower back and pelvis
2.6
7.8
55
219
85100
ICD-8 Finland
Cerebral laceration and contusion, Without mention of open intracranial wound
45.2
7.7
9
*
F06.2
ICD-10 Finland
Organic delusional [schizophrenia-like] disorder
45.2
7.7
9
*
2152
FHL
Extraction, big brain
45.2
7.7
9
*
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.6
7.7
179
1135
R60.9
ICD-10 Finland
Oedema, unspecified
2.6
7.7
54
214
F20.04
ICD-10 Finland
Paranoid schizophrenia with partial recurrence
5.9
7.7
20
34
H53.4
ICD-10 Finland
Visual field defects
3.6
7.7
32
89
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
3.0
7.6
42
144
78259
ICD-8 Finland
Symptoms referable to cardiovascular and lymphatic system, Syncope (lipothymia) alia sive NUD
18.4
7.6
11
6
M41.4
ICD-10 Finland
Neuromuscular scoliosis
25.1
7.6
10
*
YX8VG
NOMESCO Finland
Stereotactic MRI exmaination with high intensity magnet for dose design of radiotherapy
25.1
7.6
10
*
F61.0
ICD-10 Finland
Mixed personality disorders
3.4
7.6
35
106
F99
ICD-10 Finland
Mental disorder, not otherwise specified
3.0
7.5
41
140
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
7.1
7.5
17
24
A29
ICPC
General symptom/complaint other
1.8
7.4
136
805
F44.9
ICD-10 Finland
Dissociative [conversion] disorder, unspecified
6.5
7.4
18
28
R32
ICD-10 Finland
Unspecified urinary incontinence
3.3
7.4
35
108
N91.4
ICD-10 Finland
Secondary oligomenorrhoea
5.6
7.4
20
36
F05
ICPC
Visual disturbance other
3.1
7.3
37
120
N03AX17
ATC
stiripentol; oral
+∞
7.3
7
*
2133
FHL
Suntin revisio
+∞
7.3
7
*
N03AF03
ATC
rufinamide; oral
+∞
7.3
7
*
C71.12
ICD-10 Finland
Malignant tumor of frontal lobe grade III glioma
+∞
7.3
7
*
4340A
ICD-9 Finland
Occlusion of cerebral arteries, Cerebral thrombosis
6.9
7.3
17
25
G81.9
ICD-10 Finland
Hemiplegia, unspecified
4.9
7.3
22
45
N03AX16
ATC
pregabalin; oral
1.5
7.3
264
1863
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
3.7
7.3
30
83
F40.9
ICD-10 Finland
Phobic anxiety disorder, unspecified
5.2
7.2
21
41
R41.0
ICD-10 Finland
Disorientation, unspecified
3.4
7.2
33
99
N30.0
ICD-10 Finland
Acute cystitis
1.6
7.2
168
1063
SPAT1263
SPAT
Sampling
1.3
7.2
591
4839
N29
ICPC
Neurological sympt/complt other
3.5
7.2
31
89
N05BA06
ATC
lorazepam; systemic, sublingual
2.3
7.2
60
261
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.5
7.2
54
223
F84.0
ICD-10 Finland
Childhood autism
30.1
7.1
9
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
7.1
169
1078
Z02.4
ICD-10 Finland
Examination for driving licence
0.6
7.1
80
1389
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
4.0
7.1
26
65
29599
ICD-8 Finland
Schizophrenia, Unspecified type
12.1
7.1
12
10
RS222
NOMESCO Finland
NA
3.9
7.1
27
70
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
8.8
7.0
14
16
G04BD07
ATC
tolterodine; oral
2.5
7.0
52
212
S42.2
ICD-10 Finland
Fracture of upper end of humerus
2.4
7.0
55
231
J46
ICD-10 Finland
Status asthmaticus
2.9
6.9
40
140
SPAT1216
SPAT
Assessment of functional ability
1.7
6.9
151
940
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
5.2
6.9
20
39
S70.0
ICD-10 Finland
Contusion of hip
2.7
6.9
45
171
F39
ICD-10 Finland
Unspecified mood [affective] disorder
2.9
6.9
38
131
XCK00
NOMESCO Finland
Perimetry
2.1
6.9
71
340
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.9
6.9
102
561
C07AA05
ATC
propranolol; systemic
1.5
6.9
270
1937
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.7
6.9
45
172
N05AA01
ATC
chlorpromazine; systemic, rectal
4.4
6.8
23
53
R35
ICD-10 Finland
Polyuria
2.2
6.8
68
321
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
6.8
277
2000
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
5.0
6.8
20
40
R50.9
ICD-10 Finland
Fever, unspecified
1.6
6.8
201
1352
F20.10
ICD-10 Finland
Raise schizophrenia continuously
11.0
6.8
12
11
2161
FHL
Neck ligation, big brain
11.0
6.8
12
11
X58
ICD-10 Finland
Exposure to other specified factors
1.6
6.8
191
1273
P01
ICPC
Feeling anxious/nervous/tense
1.6
6.8
188
1248
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.9
6.8
103
572
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
6.8
322
2398
F81.3
ICD-10 Finland
Mixed disorder of scholastic skills
5.7
6.8
18
32
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
6.8
229
1591
E87.6
ICD-10 Finland
Hypokalaemia
3.0
6.7
36
122
SPAT1251
SPAT
Organisation of medication
2.6
6.7
44
169
IEY01
NOMESCO Finland
Psychoeducation, individual
4.9
6.7
20
41
N28
ICPC
Limited function/disability (N)
4.4
6.7
22
50
G43.9
ICD-10 Finland
Migraine, unspecified
1.9
6.6
100
555
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.4
6.6
51
214
Z31.5
ICD-10 Finland
Genetic counselling
1.9
6.6
86
454
30180
ICD-8 Finland
Personality disorders, Immatura
12.3
6.6
11
9
P76
ICPC
Depressive disorder
1.8
6.6
103
579
P85
ICPC
Mental retardation
10.1
6.5
12
12
W10
ICD-10 Finland
Fall on and from stairs and steps
2.2
6.5
59
269
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.3
6.5
56
250
SPAT1234
SPAT
Support of social functional capacity
2.3
6.5
56
250
R4150
NOMESCO Finland
Neuropsychological rehabilitation
5.7
6.5
17
30
F72.0
ICD-10 Finland
Severe mental retardation, with the statement of no, or minimal, impairment of behaviour
70.1
6.4
7
*
F71.1
ICD-10 Finland
Moderate mental retardation, significant impairment of behaviour requiring attention or treatment
70.1
6.4
7
*
C71.20
ICD-10 Finland
Malignant tumor in temporal lobe without histology
70.1
6.4
7
*
S01.9
ICD-10 Finland
Open wound of head, part unspecified
3.5
6.4
28
82
A10AA02
ATC
NA
2.4
6.4
52
224
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
14.4
6.4
10
7
IEZ99
NOMESCO Finland
Other psychiatric rehabilitation intervention
14.4
6.4
10
7
S60.2
ICD-10 Finland
Contusion of other parts of wrist and hand
2.0
6.4
74
374
R4120
NOMESCO Finland
Occupational therapy
2.0
6.4
80
416
R1250
NOMESCO Finland
Evaluation of functional capability
3.0
6.3
34
116
30300
ICD-8 Finland
Alcoholism, Episodic excessive drinking
6.6
6.3
15
23
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
2.7
6.3
41
155
7819X
ICD-9 Finland
Symptoms involving nervous and musculoskeletal systems, Other symptoms involving nervous and musculoskeletal systems[SYMPTOMATA ALIA SYSTEMATIS NERVORUM ET MUSCULOSCEL]
4.6
6.3
20
44
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
2.2
6.3
57
260
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
6.3
143
905
199
Kela drug reimbursment
Rufinamide
+∞
6.3
6
*
3457B
ICD-9 Finland
Epilepsy, Epilepsia partialis continua[EPILEPSIA PARTIALIS CONTINUA]
+∞
6.3
6
*
AAJ20
NOMESCO Finland
Excision of epileptic focus
+∞
6.3
6
*
34533
ICD-8 Finland
Epilepsy, Partialis (focalis) alia
+∞
6.3
6
*
F71.9
ICD-10 Finland
Moderate mental retardation, without mention of impairment of behaviour
+∞
6.3
6
*
Z30.0
ICD-10 Finland
General counselling and advice on contraception
1.7
6.2
113
669
R25.2
ICD-10 Finland
Cramp and spasm
2.9
6.2
34
118
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
3.1
6.2
31
101
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.3
6.2
53
233
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
3.9
6.2
23
59
K07
ICPC
Swollen ankles/oedema
2.7
6.2
40
151
R5599
NOMESCO Finland
Other rehabilitation service
2.6
6.2
41
159
R05
ICPC
Cough
1.4
6.1
297
2216
G04BD04
ATC
oxybutynin; oral, transdermal
2.2
6.1
56
256
G93.0
ICD-10 Finland
Cerebral cysts
7.7
6.1
13
17
N06AB03
ATC
fluoxetine; oral
1.6
6.1
152
981
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
2.3
6.1
53
237
C02AC05
ATC
moxonidine; oral
2.6
6.1
41
161
G25.0
ICD-10 Finland
Essential tremor
2.9
6.1
33
114
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
8.6
6.1
12
14
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
10.1
6.0
11
11
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.9
6.0
84
457
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
421
162
33.83
307.65
4.9
5.9
395.4
372.0
umol/l
1.08
387
136
664
3301
2.62
77.88
3.3
2.0
186.9
210.9
u/l
0.43
648
3137
911
5907
2.12
51.52
7.2
7.0
1.2
1.2
mmol/l
2.07
776
5051
833
5309
2.08
48.33
6.4
6.7
1.2
1.2
mmol/l
2.89
779
4865
127
347
3.87
40.76
2.5
2.4
335.6
335.4
ug/l
0.00
119
324
1032
7456
1.93
38.41
6.0
4.8
6.4
6.5
mmol/l
0.36
963
6850
92
266
3.59
27.13
2.7
3.7
35.3
34.1
umol/l
0.22
80
233
651
4662
1.63
20.19
3.8
3.3
28.9
31.2
u/l
1.15
620
4452
694
5067
1.61
19.78
5.0
5.1
35.7
36.5
g/l
3.42
649
4736
229
1219
2.01
19.47
4.1
5.8
1.2
1.7
mmol/l
1.26
182
971
313
1851
1.84
19.39
2.1
1.8
—
—
—
0
0
217
1142
2.03
19.03
7.6
8.6
1.0
1.0
mmol/l
0.12
171
894
557
3884
1.63
18.97
2.6
2.5
60.5
56.3
u/l
0.21
522
3631
836
6431
1.57
18.75
5.8
6.0
8.8
11.7
umol/l
8.26
781
6075
227
1226
1.98
18.48
4.2
5.8
5.8
5.8
kpa
0.05
212
1190
215
1149
1.99
18.02
7.5
8.5
5.1
5.1
kpa
0.03
208
1096
215
1150
1.99
17.98
7.5
8.5
13.1
12.7
kpa
0.38
207
1101
310
1881
1.79
17.50
3.8
4.5
0.8
0.8
mmol/l
0.27
292
1776
1546
13927
1.90
17.28
18.6
12.4
138.7
139.6
mmol/l
25.51
1508
13551
1173
9896
1.55
16.32
7.3
6.9
78.7
79.3
u/l
0.20
1097
9332
179
929
2.03
16.24
8.4
9.2
122.9
123.0
g/l
0.03
170
902
985
8076
1.50
15.09
10.6
9.0
3.9
4.0
e9/l
0.52
859
7068
1538
13970
1.79
14.83
18.3
12.5
4.0
3.9
mmol/l
2.43
1498
13571
545
3968
1.54
14.68
2.9
3.2
2.3
2.4
mmol/l
2.13
480
3570
567
4183
1.52
14.29
4.0
3.1
28.8
41.0
ng/l
0.91
329
2370
293
1848
1.70
14.21
1.7
1.7
1119.2
1146.4
nmol/l
0.19
232
1435
217
1256
1.83
14.16
1.9
1.7
—
—
—
0
0
216
1275
1.79
13.18
1.9
1.7
—
—
—
0
0
182
1020
1.87
13.14
6.0
8.7
1.3
1.3
mmol/l
0.54
169
970
605
4592
1.48
13.02
1.9
1.8
96.3
96.5
pmol/l
0.04
327
2497
122
600
2.11
12.77
8.8
7.2
24.8
24.4
mmol/l
0.50
114
562
188
1074
1.84
12.77
3.8
5.3
4.9
4.8
kpa
0.08
174
1039
172
958
1.88
12.65
4.1
5.8
5.2
5.1
kpa
0.55
162
903
698
5501
1.45
12.14
2.5
2.4
72.7
73.6
nmol/l
0.33
630
5091
320
2143
1.60
12.13
4.0
3.3
345.5
549.2
ng/l
0.47
208
1405
164
920
1.86
11.79
4.2
5.9
0.9
1.4
mmol/l
1.15
117
667
28
64
4.43
11.46
2.0
3.9
183.1
150.9
umol/l
0.16
14
36
102
492
2.14
11.24
4.3
4.0
24.8
25.2
mmol/l
0.45
96
478
127
666
1.98
11.17
4.5
4.7
128.7
129.9
g/l
0.22
119
651
109
546
2.06
10.89
10.2
11.7
—
—
—
0
0
276
1838
1.59
10.62
2.1
2.6
28.9
29.7
s
1.09
266
1789
118
620
1.97
10.33
1.6
1.5
—
—
—
0
0
1039
8951
1.39
10.14
5.0
3.9
416.0
1927.7
e6/l
1.12
23
115
40
129
3.15
10.06
1.4
1.3
—
—
—
0
0
212
1342
1.66
9.98
6.9
7.7
104.3
104.5
mmol/l
0.16
202
1314
357
2550
1.50
9.96
1.6
1.5
20.0
20.4
nmol/l
0.22
328
2236
199
1240
1.68
9.95
2.7
2.4
34.2
77.6
u/l
0.57
180
1047
27
69
3.96
9.60
1.8
1.6
—
—
—
0
0
71
321
2.26
9.22
1.5
1.9
5.1
14.0
e6/l
1.47
56
254
71
321
2.26
9.22
1.5
2.0
881.8
1393.5
e6/l
0.21
61
261
416
3123
1.43
8.88
1.7
2.0
1.3
1.0
mg/l
0.46
310
2318
75
353
2.17
8.84
1.3
1.8
543.7
489.1
mg/l
0.20
70
337
67
306
2.24
8.51
3.3
4.8
24.0
24.5
mmol/l
0.50
59
271
91
469
1.99
8.45
4.7
4.2
50.4
50.3
%
0.03
86
463
135
791
1.77
8.42
3.9
6.4
23.8
23.9
mmol/l
0.22
123
734
76
370
2.10
8.24
2.8
1.9
1.1
2.1
ug/l
0.66
67
327
22
55
4.04
8.07
1.2
1.4
—
—
—
0
0
22
55
4.04
8.07
1.2
1.4
—
—
—
0
0
111
629
1.82
7.76
7.9
11.0
1.3
1.4
%
0.15
111
624
80
409
2.00
7.63
7.9
5.7
2.0
1.6
%
1.26
73
384
191
1271
1.56
7.29
3.1
3.4
1.8
1.7
%
0.41
167
1156
176
1159
1.58
7.03
2.0
2.8
0.2
0.2
g/l
0.24
169
1094
62
301
2.10
6.82
1.4
1.3
—
—
—
0
0
1104
9909
1.31
6.61
3.9
3.0
53.7
41.2
u/l
5.97
1064
9449
381
2949
1.37
6.59
4.1
3.5
1.0
1.0
kg/l
0.69
65
417
48
215
2.27
6.46
2.5
2.3
16.4
16.6
%
0.11
22
118
1578
14999
1.50
6.26
11.5
9.0
28.2
26.8
u/l
0.24
1527
14553
232
1662
1.46
6.22
5.8
7.0
1.1
1.1
mmol/l
0.01
215
1566
131
841
1.60
5.85
1.8
1.7
—
—
—
0
0
413
3293
1.33
5.81
2.2
2.2
2.7
2.8
mg/l
0.29
349
2841
119
753
1.62
5.65
2.6
3.0
108.4
161.0
ng/l
1.48
109
673
88
516
1.74
5.56
5.0
7.0
9.0
9.3
kpa
0.77
83
487
277
2092
1.38
5.51
1.9
1.8
1.5
1.4
%
0.81
257
1884
193
1375
1.45
5.33
1.9
2.1
386.0
365.2
nmol/l
0.70
181
1280
50
247
2.05
5.33
2.2
2.4
131.4
132.9
g/l
0.22
40
194
1509
14326
1.37
5.08
17.1
11.5
22.0
21.6
mg/l
0.21
1244
11048
55
287
1.95
5.05
4.2
4.0
3.9
3.9
mmol/l
0.03
47
265
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
22
77
2.88
4.93
1.0
1.1
—
—
—
0
0
1255
13383
0.78
4.91
3.9
3.7
1.5
1.5
mmol/l
0.54
1172
12601
21
72
2.94
4.88
1.1
1.1
—
—
—
0
0
44
215
2.07
4.85
1.5
1.5
—
—
—
0
0
1200
12850
0.79
4.76
3.5
3.4
1.3
1.3
mmol/l
2.05
1118
12086
1376
12925
1.29
4.74
5.3
4.5
1.9
1.9
mu/l
0.15
1290
12105
1280
13599
0.79
4.70
4.3
4.0
2.8
2.8
mmol/l
0.36
1195
12779
300
2352
1.33
4.66
1.6
1.6
453.2
43286207.3
pmol/l
3.07
254
2033
327
2599
1.32
4.62
2.5
2.6
9.1
6.6
e6/l
1.14
289
2283
168
1201
1.44
4.57
2.5
4.4
236.8
256.8
u/l
0.65
160
1140
128
867
1.51
4.56
3.7
4.8
83.2
77.8
ng/l
0.24
107
789
10
21
4.78
4.53
1.1
1.1
—
—
—
0
0
148
1039
1.46
4.43
2.2
2.3
7167.1
6221.5
u/l
0.13
66
429
51
273
1.89
4.39
1.4
1.4
—
—
—
0
0
1269
13455
0.80
4.27
4.0
3.8
4.7
4.7
mmol/l
0.36
1195
12731
12
31
3.89
4.26
3.7
2.8
—
—
—
0
0
12
31
3.89
4.26
3.7
2.8
—
—
—
0
0
71
427
1.69
4.17
2.0
1.8
—
—
—
0
0
78
483
1.64
4.11
2.2
1.8
—
—
—
0
0
106
710
1.52
4.01
1.8
1.5
—
—
—
0
0
325
2635
1.29
3.93
2.8
3.1
744.3
1167.4
ng/l
2.33
261
2192
60
351
1.73
3.91
4.0
4.1
1.4
1.4
mmol/l
0.05
60
343
127
1777
0.69
3.89
2.6
2.7
0.7
0.8
ug/l
0.33
80
1030
18
65
2.79
3.86
1.6
1.5
—
—
—
0
0
253
1994
1.31
3.78
2.5
2.9
5.9
2.6
e6/l
2.05
145
1063
1552
14924
1.34
3.76
17.5
12.5
69.4
72.7
umol/l
3.29
1552
14919
78
500
1.59
3.61
1.1
1.1
2.2
4.7
u/ml
0.75
12
73
1182
11040
1.21
3.57
4.5
3.9
14.0
14.5
pmol/l
12.24
1101
10236
70
440
1.62
3.52
1.7
2.1
1.2
1.4
g/l
0.72
63
394
243
1931
1.30
3.42
2.3
2.5
13.2
14.2
umol/l
1.34
225
1799
409
3460
1.24
3.41
2.9
3.1
0.3
0.3
e6/l
0.05
323
2556
225
1771
1.31
3.40
2.3
2.4
2.4
2.4
g/l
0.25
211
1647
34
175
1.96
3.35
1.2
1.2
—
—
—
0
0
159
1200
1.36
3.20
17.9
18.4
1.2
1.2
inr
0.10
28
180
121
1647
0.72
3.18
1.4
1.6
—
—
—
0
0
122
883
1.41
3.17
4.1
3.6
1.2
1.2
mmol/l
2.45
111
754
30
152
1.99
3.10
1.3
1.5
—
—
—
0
0
205
1617
1.30
3.06
2.3
2.6
23.3
23.9
%
0.19
160
1410
429
3689
1.22
3.03
3.5
3.5
7.7
8.1
mmol/l
0.67
360
3197
29
149
1.96
2.90
1.2
1.5
—
—
—
0
0
29
149
1.96
2.90
1.2
1.5
—
—
—
0
0
86
595
1.47
2.86
1.3
1.4
—
—
—
0
0
29
150
1.95
2.85
1.2
1.5
—
—
—
0
0
1066
9963
1.18
2.82
4.2
3.9
10.5
10.0
mm/h
0.63
998
9322
239
1952
1.26
2.72
2.5
2.7
2.4
2.4
mmol/l
0.46
209
1707
110
806
1.39
2.70
1.9
2.2
7.3
7.6
ug/l
0.02
90
721
18
79
2.29
2.68
1.2
1.3
244110.8
25900.9
e6/l
0.79
12
47
166
1299
1.31
2.65
7.2
5.8
—
—
—
0
0
81
565
1.45
2.61
1.3
1.2
0.2
1.3
u/ml
—
6
48
436
3803
1.19
2.61
1.3
1.4
2.0
1.6
u/ml
0.27
102
995
28
148
1.91
2.61
1.3
1.5
—
—
—
0
0
9
25
3.61
2.57
1.0
1.1
—
—
—
0
0
27
142
1.92
2.56
7.2
6.0
10.6
10.4
mg/l
0.07
22
129
140
1077
1.33
2.53
7.8
9.2
7.5
8.1
mmol/l
0.59
133
1033
14
56
2.51
2.53
1.0
1.1
—
—
—
0
0
101
739
1.39
2.51
1.8
1.8
—
—
—
0
0
30
165
1.83
2.49
1.0
1.1
—
—
—
0
0
1312
12530
1.18
2.48
21.0
14.1
13.3
13.5
%
4.53
1289
12274
62
415
1.51
2.46
1.9
2.0
—
—
—
0
0
28
152
1.86
2.43
1.3
1.5
—
—
—
0
0
46
711
0.64
2.40
1.2
1.7
3.6
3.6
mg/l
0.02
27
484
250
2084
1.23
2.38
2.4
2.7
1.1
1.2
e6/l
0.11
141
1145
30
168
1.80
2.37
1.0
1.1
—
—
—
0
0
25
132
1.91
2.36
1.1
1.2
31.5
40.4
mg/l
0.68
19
105
155
1229
1.29
2.27
1.3
1.2
117.8
141.9
iu/ml
0.34
54
485
64
445
1.45
2.15
1.7
1.6
0.2
0.2
g/l
2.11
55
421
53
356
1.50
2.11
1.5
1.2
35.6
9.6
u/ml
—
8
53
19
95
2.01
2.11
2.6
2.7
—
—
—
0
0
30
175
1.73
2.10
3.3
3.5
0.9
1.5
%
0.79
23
145
5
10
5.01
2.07
1.6
1.1
46.0
11.4
nmol/l
—
5
10
26
146
1.79
2.07
1.1
1.4
288.3
445.2
pmol/l
0.88
21
108
121
942
1.31
2.05
2.5
3.4
4.5
4.7
pmol/l
1.57
107
844
27
154
1.76
2.04
1.0
1.1
—
—
—
0
0
6
15
4.01
2.04
1.0
1.2
—
—
—
0
0
65
463
1.42
1.95
1.6
1.6
1.1
1.2
g/l
0.66
56
436
5
11
4.56
1.94
1.0
1.3
—
—
—
0
0
50
340
1.48
1.90
3.3
2.9
—
—
—
0
0
17
85
2.01
1.90
1.4
2.8
2.5
2.1
u/field
0.12
11
41
30
181
1.67
1.89
1.2
1.5
—
—
—
0
0
26
151
1.73
1.87
1.2
1.6
—
—
—
0
0
52
360
1.46
1.82
1.3
1.4
290.7
310.6
ug/g
0.31
32
200
9
35
2.58
1.80
4.6
2.5
—
—
—
0
0
22
124
1.78
1.76
1.1
1.1
—
—
—
0
0
27
162
1.68
1.75
1.3
1.6
—
—
—
0
0
360
3199
1.16
1.69
2.3
2.2
—
—
—
0
0
730
6803
1.12
1.66
3.9
3.2
0.0
0.0
estimate
0.80
143
1274
34
220
1.56
1.65
1.2
1.6
—
—
—
0
0
13
62
2.10
1.65
1.0
1.0
—
—
—
0
0
691
6421
1.13
1.64
4.6
4.0
—
—
—
0
0
16
83
1.94
1.64
1.5
1.7
—
—
—
0
0
38
253
1.51
1.63
1.9
1.9
—
—
—
0
0
19
105
1.82
1.63
1.3
1.6
—
—
—
0
0
19
105
1.82
1.63
1.3
1.6
—
—
—
0
0
19
105
1.82
1.63
1.3
1.6
—
—
—
0
0
10
43
2.33
1.60
1.1
1.4
—
—
—
0
0
10
43
2.33
1.60
1.1
1.4
—
—
—
0
0
47
329
1.44
1.59
1.4
1.7
—
—
—
0
0
12
57
2.11
1.55
1.5
1.7
—
—
—
0
0
12
57
2.11
1.55
1.5
1.7
—
—
—
0
0
12
57
2.11
1.55
1.5
1.7
—
—
—
0
0
12
57
2.11
1.55
1.5
1.7
—
—
—
0
0
5
15
3.34
1.52
1.0
1.0
—
—
—
0
0
208
2409
0.85
1.50
3.5
3.8
21.4
21.2
%
0.05
75
991
9
37
2.44
1.48
1.1
1.4
11.1
8.0
ug/l
—
9
37
138
1143
1.22
1.46
3.9
2.9
—
—
—
0
0
733
6870
1.11
1.46
3.9
3.3
0.0
0.0
estimate
1.06
142
1266
16
87
1.85
1.46
1.1
1.0
—
—
—
0
0
11
52
2.12
1.44
1.2
1.7
—
—
—
0
0
37
253
1.47
1.43
1.1
1.3
2.5
4.9
u/ml
1.65
15
115
37
255
1.46
1.39
2.9
3.7
46.2
77.9
mg/l
0.60
29
201
37
255
1.46
1.39
2.9
3.7
31.9
31.6
mg/l
0.02
30
202
11
53
2.08
1.38
1.2
1.7
—
—
—
0
0
12
61
1.97
1.33
1.1
1.2
—
—
—
0
0
38
266
1.44
1.33
1.2
1.1
52.0
1729.0
iu/ml
—
8
78
1307
12674
1.12
1.32
13.3
9.9
95.4
89.5
ml/min/173m2
16.10
1061
10257
6
24
2.50
1.30
1.0
1.7
—
—
—
0
0
10
48
2.09
1.27
1.0
1.0
—
—
—
0
0
10
48
2.09
1.27
1.0
1.1
—
—
—
0
0
723
6816
1.10
1.24
5.3
4.5
0.0
0.0
estimate
0.50
149
1316
9
45
2.01
1.23
1.0
1.0
—
—
—
0
0
12
63
1.91
1.23
1.2
1.6
—
—
—
0
0
18
108
1.67
1.22
1.7
1.5
—
—
—
0
0
5
19
2.64
1.21
1.0
4.9
—
—
—
0
0
5
19
2.64
1.21
1.0
1.0
—
—
—
0
0
6
26
2.31
1.18
1.0
1.2
—
—
—
0
0
338
3066
1.13
1.18
2.4
2.2
—
—
—
0
0
37
266
1.40
1.15
6.1
3.4
17.7
25.6
mg/l
1.53
26
173
95
781
1.23
1.13
2.7
2.8
66.9
66.9
g/l
0.03
90
724
33
233
1.42
1.13
1.5
1.7
—
—
—
0
0
178
1553
1.16
1.11
2.7
3.4
4.8
7.4
umol/l
3.06
145
1325
7
31
2.26
1.10
1.0
1.1
—
—
—
0
0
57
727
0.78
1.09
1.4
1.5
—
—
—
0
0
5
21
2.38
1.09
1.0
1.0
—
—
—
0
0
303
2748
1.12
1.07
2.1
2.1
—
—
—
0
0
273
3020
0.89
1.07
3.5
4.2
1.7
2.2
ug/l
1.69
247
2725
30
212
1.42
1.04
1.3
1.9
—
1217.8
—
0
9
9
46
1.96
1.03
1.0
1.0
—
—
—
0
0
20
130
1.54
1.02
1.2
1.4
0.2
0.8
u/ml
—
7
55
19
122
1.56
1.02
3.5
2.9
—
—
—
0
0
5
109
0.46
1.00
1.0
1.6
—
—
—
0
0
46
594
0.77
0.99
1.4
1.5
—
—
—
0
0
5
23
2.18
0.98
1.2
1.3
—
—
—
0
0
0
30
0.00
0.97
0.0
1.9
—
1.9
—
0
15
52
657
0.79
0.95
1.7
1.7
—
—
—
0
0
342
3149
1.11
0.93
4.4
4.1
14.4
15.4
mg/mmol
0.06
239
2081
35
260
1.35
0.93
1.1
1.3
7.3
5.0
u/ml
0.17
14
89
10
55
1.82
0.92
4.6
3.3
—
—
—
0
0
26
184
1.42
0.91
1.2
1.3
—
—
—
0
0
35
261
1.35
0.91
1.4
1.3
—
—
—
0
0
35
261
1.35
0.91
1.4
1.3
—
—
—
0
0
559
5274
1.09
0.91
4.1
3.3
—
—
—
0
0
18
119
1.52
0.88
2.2
1.7
55.0
58.8
%
0.16
12
85
38
290
1.32
0.86
1.0
1.1
2.0
2.3
u/ml
0.13
15
134
15
96
1.57
0.84
1.0
1.1
0.9
1.1
u/l
—
6
50
8
46
1.74
0.82
1.8
1.7
—
—
—
0
0
8
46
1.74
0.82
1.8
1.7
—
—
—
0
0
16
105
1.53
0.81
2.8
3.1
55.3
53.8
%
—
10
76
99
850
1.17
0.80
1.7
1.6
300.1
299.9
mu/l
0.00
89
766
8
47
1.71
0.80
1.8
1.7
—
—
—
0
0
8
47
1.71
0.80
1.1
1.3
—
—
—
0
0
8
48
1.67
0.78
1.0
1.1
—
—
—
0
0
0
26
0.00
0.78
0.0
1.3
—
—
—
0
0
125
1100
1.15
0.75
3.1
2.9
11.0
10.3
g/l
1.05
117
1022
12
75
1.60
0.75
1.0
1.2
—
—
—
0
0
356
3324
1.09
0.74
1.7
1.7
1.4
1.4
mmol/l
0.38
315
2884
259
2802
0.91
0.70
1.5
1.5
—
—
—
0
0
15
101
1.49
0.70
1.1
1.1
—
—
—
0
0
19
135
1.41
0.69
1.1
1.6
—
—
—
0
0
19
135
1.41
0.69
3.3
2.8
7.6
11.2
%
1.82
11
86
10
61
1.64
0.68
1.3
1.3
—
78.0
—
0
10
22
161
1.37
0.68
1.2
1.3
0.5
0.6
nmol/l
0.21
22
154
41
329
1.25
0.68
1.6
1.7
—
—
—
0
0
17
119
1.43
0.67
3.2
2.0
33.9
32.5
pg
0.87
17
119
58
485
1.20
0.66
1.6
1.6
0.1
0.2
iu/ml
0.45
15
88
30
233
1.29
0.64
1.2
1.4
7.3
7.0
mmol/l
0.25
24
161
42
341
1.24
0.64
1.2
1.3
—
—
—
0
0
380
3589
1.07
0.61
4.3
3.5
0.0
0.0
estimate
1.49
143
1278
22
165
1.34
0.60
1.4
1.6
—
—
—
0
0
63
736
0.85
0.60
2.2
1.9
—
—
—
0
0
38
309
1.23
0.58
1.0
1.1
0.2
0.4
u/ml
—
9
88
151
1372
1.11
0.58
4.0
3.8
32.0
31.4
%
0.28
109
994
6
35
1.72
0.57
3.0
6.4
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
37
301
1.23
0.57
3.5
4.9
0.3
0.3
u/ml
0.79
18
164
33
265
1.25
0.57
5.8
4.4
57.2
55.9
%
0.19
33
265
8
55
1.46
0.56
1.0
1.3
—
—
—
0
0
11
160
0.69
0.55
1.0
1.1
—
—
—
0
0
31
248
1.25
0.55
3.1
5.1
—
1472.7
—
0
20
22
168
1.31
0.55
1.2
1.4
10.1
12.6
mmol/l
—
5
34
120
1082
1.12
0.54
1.4
1.3
150.3
243.4
u/ml
1.18
103
1001
21
160
1.32
0.53
1.6
1.8
—
—
—
0
0
9
63
1.43
0.52
1.0
1.3
—
—
—
0
0
42
351
1.20
0.51
1.1
1.2
—
—
—
0
0
75
659
1.14
0.51
1.4
1.5
8.1
8.5
u/l
0.10
62
525
40
333
1.21
0.51
1.4
1.6
80.3
97.1
u/ml
—
6
61
25
197
1.27
0.51
1.4
1.6
—
—
—
0
0
16
118
1.36
0.50
1.0
1.2
—
—
—
0
0
34
279
1.22
0.50
1.4
1.3
15.2
19.4
u/l
0.47
25
242
257
2414
1.08
0.49
1.3
1.3
25.4
26.1
iu/ml
0.04
86
724
42
353
1.19
0.49
1.9
3.1
5.0
7.1
umol/l
0.74
33
266
111
1004
1.11
0.49
1.4
1.5
25.1
23.3
iu/l
0.25
96
823
16
119
1.35
0.48
1.0
1.2
—
—
—
0
0
16
119
1.35
0.48
1.0
1.4
1.9
1.4
nmol/l
1.48
16
110
17
128
1.33
0.47
1.8
1.8
—
—
—
0
0
39
327
1.20
0.47
1.7
2.3
3.0
3.1
g/l
0.16
26
265
12
85
1.41
0.47
1.2
1.5
2.5
8.4
u/l
—
6
40
35
291
1.21
0.46
1.7
1.4
—
—
—
0
0
16
120
1.34
0.46
2.8
2.2
18.7
19.8
mg/l
—
6
34
42
356
1.18
0.46
1.4
1.5
—
13.9
—
0
5
7
49
1.43
0.46
2.7
2.6
—
—
—
0
0
32
384
0.83
0.44
2.5
3.6
92.8
3693.1
u/ml
0.77
25
327
49
566
0.86
0.44
1.4
1.5
—
—
—
0
0
6
92
0.65
0.42
1.2
1.2
—
—
—
0
0
197
1846
1.08
0.42
2.0
2.0
—
—
—
0
0
5
32
1.56
0.42
2.6
2.3
—
—
—
0
0
31
258
1.21
0.42
5.7
4.0
4.3
4.1
e9/l
0.14
31
258
21
167
1.26
0.41
1.2
1.3
—
—
—
0
0
106
969
1.10
0.40
1.4
1.4
—
—
—
0
0
5
36
1.39
0.38
1.2
1.1
—
—
—
0
0
13
170
0.76
0.38
1.2
1.1
—
—
—
0
0
139
1493
0.93
0.37
1.4
1.5
—
—
—
0
0
57
506
1.13
0.37
1.4
1.3
—
—
—
0
0
40
346
1.16
0.37
1.7
2.3
7.2
7.2
g/l
0.03
27
272
40
346
1.16
0.37
1.7
2.3
—
—
—
0
0
40
346
1.16
0.37
1.7
2.3
4.0
3.7
g/l
0.61
25
259
13
99
1.32
0.35
1.1
1.2
1.2
1.0
ratio
—
5
43
107
988
1.09
0.35
1.1
1.1
—
—
—
0
0
1144
11594
0.96
0.32
3.7
3.5
—
—
—
0
0
16
128
1.25
0.32
1.1
1.2
54.9
67.8
u/l
—
10
89
67
608
1.11
0.32
1.3
1.5
—
—
—
0
0
29
248
1.17
0.31
1.1
1.1
—
—
—
0
0
14
110
1.27
0.31
1.6
1.4
—
—
—
0
0
7
96
0.73
0.31
2.3
1.7
—
—
—
0
0
7
97
0.72
0.31
4.1
4.0
—
—
—
0
0
10
75
1.34
0.30
1.1
1.1
1413.8
1569.3
miu/ml
—
10
75
31
356
0.87
0.29
2.0
1.8
—
—
—
0
0
50
449
1.12
0.29
1.2
1.1
—
—
—
0
0
20
167
1.20
0.28
3.3
4.1
5102.1
316.5
u/ml
0.45
20
157
702
6878
1.03
0.28
3.0
2.9
112.2
95.2
ug/l
0.73
655
6490
17
140
1.22
0.27
1.5
1.7
—
—
—
0
0
18
214
0.84
0.26
2.1
1.5
—
—
—
0
0
5
73
0.68
0.26
1.6
1.8
—
—
—
0
0
44
397
1.11
0.25
1.7
2.1
3.0
4.9
iu/l
2.76
13
157
13
159
0.82
0.24
1.1
1.6
—
—
—
0
0
39
350
1.12
0.24
1.0
1.1
5.9
6.9
u/ml
0.08
20
148
325
3152
1.04
0.23
2.5
2.6
7880.5
5027.9
umol/l
0.38
281
2828
49
447
1.10
0.23
1.2
1.1
—
—
—
0
0
14
116
1.21
0.22
1.2
1.2
—
—
—
0
0
14
116
1.21
0.22
1.2
1.2
—
—
—
0
0
14
116
1.21
0.22
1.2
1.2
—
—
—
0
0
14
116
1.21
0.22
1.2
1.2
—
—
—
0
0
1622
16285
0.95
0.21
25.5
16.9
6.7
6.8
e9/l
0.20
1586
15871
1620
16265
0.95
0.21
25.6
16.9
249.7
257.2
e9/l
5.21
1587
15884
5
42
1.19
0.21
5.2
8.2
—
—
—
0
0
5
42
1.19
0.21
1.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
36
325
1.11
0.21
1.1
1.1
7.0
7.1
u/ml
0.00
15
139
39
354
1.10
0.21
1.8
1.6
—
—
—
0
0
14
117
1.20
0.20
1.2
1.2
—
—
—
0
0
237
2293
1.04
0.20
1.3
1.3
8.9
10.2
u/ml
0.13
78
939
0
14
0.00
0.20
0.0
9.4
—
—
—
0
0
0
14
0.00
0.20
0.0
3.6
—
4.5
—
0
14
6
48
1.25
0.20
1.0
1.0
—
—
—
0
0
402
3928
1.03
0.20
1.8
1.7
—
—
—
0
0
17
146
1.17
0.19
1.4
2.0
—
—
—
0
0
1623
16289
0.95
0.19
25.6
17.0
134.4
136.4
g/l
7.31
1608
16098
66
702
0.94
0.17
1.3
1.3
288.9
226.1
miu/ml
0.70
30
352
1391
13990
0.97
0.17
18.8
12.5
39.1
40.3
%
5.58
1031
11272
81
853
0.95
0.16
1.3
1.5
—
—
—
0
0
14
120
1.17
0.16
1.2
1.1
—
—
—
0
0
74
781
0.95
0.16
1.3
1.5
—
—
—
0
0
1623
16281
0.96
0.16
25.4
16.9
4.5
4.6
e12/l
14.21
1589
15876
15
130
1.16
0.15
1.8
3.0
0.2
0.2
e9/l
—
9
109
74
780
0.95
0.15
1.3
1.5
—
—
—
0
0
74
780
0.95
0.15
1.3
1.5
—
—
—
0
0
6
79
0.76
0.15
1.3
1.1
111.7
205.4
iu/ml
—
6
79
92
962
0.95
0.15
1.5
1.5
—
—
—
0
0
74
777
0.95
0.14
1.3
1.5
—
—
—
0
0
29
266
1.09
0.14
1.9
1.7
5699.0
11777.7
e6/l
1.30
21
197
48
451
1.07
0.13
1.1
1.1
5.2
3.6
u/ml
0.14
13
124
45
422
1.07
0.13
1.3
1.4
—
—
—
0
0
15
133
1.13
0.12
1.9
2.9
330.4
512.9
e6/l
—
9
109
61
583
1.05
0.10
1.6
1.8
—
—
—
0
0
43
407
1.06
0.10
1.3
1.5
270.0
225.8
u/ml
0.37
23
238
17
187
0.91
0.10
1.2
1.2
—
—
—
0
0
14
125
1.12
0.10
1.1
1.2
5.4
5.3
umol/l
0.04
14
116
1283
12880
0.99
0.09
4.1
3.7
5.8
5.8
mmol/l
0.49
1192
11968
12
134
0.89
0.08
1.0
1.1
—
—
—
0
0
37
351
1.06
0.08
1.9
1.5
—
—
—
0
0
5
63
0.79
0.08
1.0
1.0
—
—
—
0
0
7
65
1.08
0.08
1.0
1.1
97.7
92.1
u/l
—
7
54
7
65
1.08
0.08
1.0
1.1
32.9
26.1
u/l
—
7
52
6
71
0.84
0.07
1.0
2.6
—
—
—
0
0
6
71
0.84
0.07
1.0
2.6
—
—
—
0
0
22
206
1.07
0.07
1.5
1.6
8.9
7.2
mmol/l
1.30
14
123
34
324
1.05
0.07
1.4
2.3
11.5
10.3
g/l
0.72
25
283
30
285
1.05
0.06
1.2
1.1
—
—
—
0
0
13
119
1.09
0.06
1.2
1.1
—
—
—
0
0
212
2094
1.01
0.05
2.1
2.7
103.0
110.0
ug/g
0.13
161
1681
1186
11825
1.01
0.05
5.4
4.7
38.7
38.6
mmol/mol
0.13
1102
11164
108
1099
0.98
0.05
2.6
2.2
10.7
12.7
nmol/l
1.74
90
980
14
150
0.93
0.04
1.3
1.4
29.2
33.9
nmol/l
0.21
14
133
52
507
1.03
0.04
1.2
1.2
—
—
—
0
0
10
109
0.92
0.04
1.9
2.1
—
—
—
0
0
11
119
0.92
0.04
1.0
1.6
9.6
11.6
umol/l
0.49
11
110
33
319
1.04
0.03
2.6
2.4
1.0
0.8
nmol/l
0.67
28
276
34
351
0.97
0.03
1.3
1.5
0.3
0.4
nmol/l
0.45
28
289
25
260
0.96
0.03
2.8
2.5
75.4
111.8
ug/min
0.26
14
166
96
947
1.01
0.03
2.4
2.5
77.2
73.2
ml/min/173m2
0.39
40
355
14
132
1.06
0.02
1.1
1.4
—
—
—
0
0
59
581
1.02
0.02
1.6
2.1
45.7
39.8
u/l
1.20
53
533
27
277
0.97
0.01
1.2
1.2
—
—
—
0
0
52
514
1.01
0.00
1.1
1.2
1.1
1.7
u/ml
0.34
23
242
30
299
1.00
0.00
1.2
1.1
—
—
—
0
0
98
981
1.00
0.00
4.3
4.3
15.5
23.2
ug/l
0.30
82
782
20
196
1.02
0.00
1.6
1.5
—
—
—
0
0
21
206
1.02
0.00
1.0
1.1
—
—
—
0
0
146
1465
1.00
0.00
1.8
1.9
—
—
—
0
0
6
68
0.88
0.00
1.5
1.1
85.3
91.5
%
—
6
59
0
5
0.00
0.00
0.0
5.0
—
—
—
0
0
8
82
0.98
0.00
2.9
1.4
8.5
7.3
u/l
—
8
67
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
5
54
0.93
0.00
1.4
1.1
66.6
89.6
%
—
5
54
0
6
0.00
0.00
0.0
3.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
1585.8
—
0
6
0
5
0.00
0.00
0.0
1.0
—
8.8
—
0
5
0
6
0.00
0.00
0.0
6.7
—
—
—
0
0
7
73
0.96
0.00
1.3
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
2.2
—
0
5
6
64
0.94
0.00
1.2
1.2
120.8
108.8
%
—
6
55
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
5.0
—
414.3
—
0
6
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
470.2
—
0
6
5
54
0.93
0.00
1.4
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
6.5
—
0
8
0
5
0.00
0.00
0.0
1.2
—
30.8
—
0
5
Mortality – FinRegistry
↥Association
Association between endpoint GE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| GE | 3.087 [2.71, 3.52] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.17 |
During the follow-up period (1.1.1998 — 31.12.2019), 687 out of 6796 females with GE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| GE | 2.745 [2.43, 3.11] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 870 out of 5793 males with GE died.
Mortality risk
Mortality risk for people of age
years, who have GE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.297% | 0.461% |
| 5 | 1.675% | 3.273% |
| 10 | 4.035% | 7.686% |
| 15 | 8.089% | 14.45% |
| 20 | 13.76% | 22.713% |
Relationships between endpoints
↥Index endpoint: GE – Generalized epilepsy
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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