Generalized epilepsy, mode (most common among epilepsy diagnosis)

GE_MODE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Check mode of ICD-10 codes: %34519, %345[0-3], %G403

Registry filters:

  • Hospital discharge: ICD-10 G40.3
  • Hospital discharge: ICD-9 %345[0-3]
  • Hospital discharge: ICD-8 %34519
  • Hospital discharge: excluded ICD-8 34511
  • Cause of death: ICD-10 G40.3
  • Cause of death: ICD-9 %345[0-3]
  • Cause of death: ICD-8 %34519
  • Cause of death: excluded ICD-8 34511

2 out of 7 registries used, show all original rules.

1283

4. Check minimum number of events

None

1283

5. Include endpoints

None

1283

6. Filter based on genotype QC (FinnGen only)

1283

Control definitions (FinnGen only)

Control exclude
G6_EPLEPSY

Extra metadata

First used in FinnGen datafreeze
DF11

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 1283 774 509
Unadjusted period prevalence (%) 0.25 0.26 0.22
Median age at first event (years) 26.47 23.71 30.66

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1180
Matched controls
11797
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G40.9
ICD-10 Finland
Epilepsy, unspecified
9457.9
323.0
544
*
N03AG01
ATC
valproic acid; systemic, rectal
52.3
323.0
647
267
G40.39
ICD-10 Finland
Other or unspecified generalized epileptic syndromes with atonic, clonic, myoclonic or tonic-clonic seizures
+∞
323.0
529
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
+∞
323.0
998
*
3451A
ICD-9 Finland
Epilepsy, Generalised convulsive epilepsy
+∞
323.0
324
*
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
+∞
307.1
281
*
183
Kela drug reimbursment
Lamotrigin and topiramate
+∞
303.6
278
*
N03AX14
ATC
levetiracetam; systemic
208.3
283.6
285
18
N03AF01
ATC
carbamazepine; oral, rectal
35.1
281.4
371
152
G40.3
ICD-10 Finland
Generalized idiopathic epilepsy and epileptic syndromes
+∞
259.2
239
*
G40.30
ICD-10 Finland
Benign myoclonic eplilepsy in infancy
+∞
229.9
213
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
26.5
226.6
323
165
N03AF02
ATC
oxcarbazepine; oral
67.2
195.2
224
41
N03AX09
ATC
lamotrigine; oral
15.3
177.7
311
269
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
+∞
168.9
158
*
G40
ICD-10 Finland
Epilepsy
+∞
166.7
156
*
G40.36
ICD-10 Finland
Juvenile myoclonic epilepsy [impulsive petit mal]
+∞
159.0
149
*
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
+∞
150.3
141
*
N05BA01
ATC
diazepam; systemic, rectal
7.0
125.4
352
673
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
+∞
120.9
114
*
N88
ICPC
Epilepsy
1174.1
111.4
107
*
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
+∞
110.2
104
*
34519
ICD-8 Finland
Epilepsy, Generalisata convulsiva NUD
+∞
108.0
102
*
G40.6
ICD-10 Finland
Grand mal seizures, unspecified (with or without petit mal)
1090.0
103.9
100
*
N05BA09
ATC
clobazam; oral
1007.0
96.4
93
*
34599
ICD-8 Finland
Epilepsy, Other and unspecified
+∞
90.8
86
*
7803A
ICD-9 Finland
General symptoms, Convulsions
48.4
90.5
110
25
N03AB02
ATC
phenytoin; systemic
117.3
90.4
97
9
3459X
ICD-9 Finland
Epilepsy, unspecified
+∞
89.7
85
*
3450A
ICD-9 Finland
Epilepsy, Generalised nonconvulsive epilepsy
+∞
78.0
74
*
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
+∞
76.9
73
*
N03AE01
ATC
clonazepam; systemic
7.9
73.9
180
263
G40.89
ICD-10 Finland
Other epilepsy
+∞
70.5
67
*
G40.35
ICD-10 Finland
Juvenile absence epilepsy
+∞
68.4
65
*
3453A
ICD-9 Finland
Epilepsy, Grand mal status
+∞
68.4
65
*
G40.10
ICD-10 Finland
Simple partial seizures
+∞
67.3
64
*
34510
ICD-8 Finland
Epilepsy, """"Grand mal""""
+∞
59.9
57
*
78020
ICD-8 Finland
Certain symptoms referable to nervous system and special senses, Convulsions
24.1
56.6
81
36
G40.09
ICD-10 Finland
Other or unspecified partial (focal) idiopathic epilepsy or epileptic syndrome with local onset
+∞
55.7
53
*
G40.33
ICD-10 Finland
Juvenile absence epilepsy
+∞
54.6
52
*
N03AD01
ATC
ethosuximide; oral
+∞
52.5
50
*
G40.00
ICD-10 Finland
Benign childhood epilepsy with centrotemporal EEG spikes
+∞
50.4
48
*
N03AX11
ATC
topiramate; oral
8.5
46.1
104
132
3454A
ICD-9 Finland
Epilepsy, Partial epilepsy, with impairment of consciousness[EPILEPSIA GENERALISATA SECUNDARIA]
+∞
45.1
43
*
N03AX18
ATC
lacosamide; systemic
+∞
44.0
42
*
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
+∞
43.0
41
*
G40.1
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
+∞
43.0
41
*
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
9.1
41.7
90
106
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
+∞
40.9
39
*
G41.9
ICD-10 Finland
Status epilepticus, unspecified
51.7
33.7
40
8
N05CD08
ATC
midazolam; nasal, systemic
11.6
32.1
60
54
AA1AD
NOMESCO Finland
CT of head and brain
2.6
29.4
255
1145
34532
ICD-8 Finland
Epilepsy, Partialis (focalis) generalisata
+∞
28.2
27
*
N03AG04
ATC
vigabatrin; oral
+∞
25.1
24
*
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
+∞
25.1
24
*
N03AX22
ATC
perampanel; oral
+∞
23.0
22
*
F02.89*G40.9
ICD-10 Finland
Dementia in epilepsy
+∞
21.9
21
*
34500
ICD-8 Finland
Epilepsy, """"Petit mal""""
+∞
21.9
21
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.8
20.8
141
541
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.2
20.6
244
1257
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.1
20.5
121
424
N03AX15
ATC
zonisamide; oral
48.9
20.2
24
5
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.9
19.9
127
467
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.6
19.6
92
272
XA800
NOMESCO Finland
Neuropsychological investigation
3.8
19.0
83
231
G40.0
ICD-10 Finland
Localization-related (focal)(partial) idiopathic epilepsy and epileptic syndromes with seizures of localized onset
+∞
18.8
18
*
G41.0
ICD-10 Finland
Grand mal status epilepticus
+∞
18.8
18
*
XA400
NOMESCO Finland
EEG
21.2
18.7
27
13
N05AX08
ATC
risperidone; systemic
2.9
18.5
115
417
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.0
18.5
114
410
G40.31
ICD-10 Finland
Benign neonatal convulsions (familial)
+∞
17.7
17
*
34598
ICD-8 Finland
Epilepsy, Alia definita
+∞
17.7
17
*
G40.7
ICD-10 Finland
Petit mal, unspecified, without grand mal seizures
+∞
17.7
17
*
181
Kela drug reimbursment
Retigabine and vigabatrin
+∞
17.7
17
*
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
6.1
17.2
47
80
N05AD01
ATC
haloperidol; systemic
5.1
17.2
54
109
N05AA02
ATC
levomepromazine; systemic
4.1
17.2
68
174
34530
ICD-8 Finland
Epilepsy, Psychomotorica
+∞
16.7
16
*
3454B
ICD-9 Finland
Epilepsy, Partial epilepsy, with impairment of consciousness[TEMPORAALIEPILEPTINEN POISSAOLOKOHTAUS]
+∞
15.7
15
*
N03AX23
ATC
brivaracetam; systemic
+∞
15.7
15
*
N05AH03
ATC
olanzapine; systemic
2.9
15.4
95
343
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.2
15.0
156
751
G40.37
ICD-10 Finland
Baltic myoclonus
+∞
14.6
14
*
G40.34
ICD-10 Finland
Epilepsy with grand mal seizures on awakening
+∞
14.6
14
*
R55
ICD-10 Finland
Syncope and collapse
2.5
14.2
117
500
W19
ICD-10 Finland
Unspecified fall
2.5
14.0
119
516
N07
ICPC
Convulsion/seizure
76.0
13.6
15
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
13.4
296
1888
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
12.7
111
488
N05AH04
ATC
quetiapine; oral
1.9
12.7
209
1209
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
4.2
12.6
47
115
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
12.6
162
852
3452A
ICD-9 Finland
Epilepsy, Petit mal status
+∞
12.5
12
*
F20.9
ICD-10 Finland
Schizophrenia, unspecified
4.6
12.4
42
93
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.8
12.2
79
295
R53
ICD-10 Finland
Malaise and fatigue
1.8
12.1
227
1372
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
6.5
11.9
30
47
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.6
11.8
88
357
N06AB04
ATC
citalopram; systemic
1.8
11.7
230
1411
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.6
11.5
84
338
3454X
ICD-9 Finland
Epilepsy, Partial epilepsy, with impairment of consciousness[ALII DISTURBATIONES CONSCIENTAE EPILEPTICI]
+∞
11.5
11
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
11.5
199
1170
N03AA02
ATC
phenobarbital; systemic
35.4
11.3
14
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.9
11.3
169
940
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.8
11.2
71
262
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
7.7
11.2
25
33
M79.6
ICD-10 Finland
Pain in limb
1.6
11.1
351
2459
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
6.2
11.1
29
48
N05CD07
ATC
temazepam; oral
2.2
11.1
109
511
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
4.6
11.0
37
82
4380A
ICD-9 Finland
Late effects of cerebrovascular disease[SEQUELAE MORBI CEREBROVASCULARIS]
15.7
10.8
17
11
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
10.7
204
1233
R42
ICD-10 Finland
Dizziness and giddiness
1.8
10.5
196
1177
G40.80
ICD-10 Finland
Epilepsy with continuous EEG spike-waves during slow wave sleep
+∞
10.4
10
*
G40.11
ICD-10 Finland
Simple partial epileptic seizure that develops into a complex partial seizure
+∞
10.4
10
*
G40.8
ICD-10 Finland
Other epilepsy
+∞
10.4
10
*
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.1
10.4
57
192
SPAT1240
SPAT
Therapeutic discussion
1.9
10.3
151
836
N05AC02
ATC
thioridazine; oral
4.5
10.2
35
80
R51.80
ICD-10 Finland
Headache
1.8
10.0
185
1105
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
9.9
219
1382
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
9.9
157
894
6489X
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Other current conditions classifiable elsewhere
16.9
9.9
15
9
A06AD11
ATC
lactulose; oral
2.0
9.8
122
631
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.9
9.7
57
201
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.3
9.7
87
390
F44.5
ICD-10 Finland
Dissociative convulsions
+∞
9.4
9
*
N05AH02
ATC
clozapine; systemic
3.8
9.4
38
102
Y0209
ICD-8 Finland
Examination of the nervous system and sensory organs, Nervous system
8.1
9.4
20
25
N04AA02
ATC
biperiden; systemic
4.2
9.3
34
83
7819X
ICD-9 Finland
Symptoms involving nervous and musculoskeletal systems, Other symptoms involving nervous and musculoskeletal systems[SYMPTOMATA ALIA SYSTEMATIS NERVORUM ET MUSCULOSCEL]
9.6
9.3
18
19
F29
ICD-10 Finland
Unspecified nonorganic psychosis
2.7
9.3
63
244
N05BA04
ATC
oxazepam; oral
1.6
9.2
249
1663
30188
ICD-8 Finland
Personality disorders, Alia definita
24.2
8.9
12
5
R11
ICD-10 Finland
Nausea and vomiting
2.1
8.9
96
471
A46
ICD-10 Finland
Erysipelas
2.0
8.6
117
627
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.2
8.6
89
425
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.2
8.6
85
401
113
Kela drug reimbursment
Anxiety disorders associated with mental retardation
16.4
8.6
13
8
G41.2
ICD-10 Finland
Complex partial status epilepticus
90.7
8.4
9
*
3458X
ICD-9 Finland
Epilepsy, Other forms of epilepsy
+∞
8.3
8
*
G41.1
ICD-10 Finland
Petit mal status epilepticus
+∞
8.3
8
*
34539
ICD-8 Finland
Epilepsy, Partialis (focalis) NUD
+∞
8.3
8
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
8.2
367
2749
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
4.7
8.1
26
56
78159
ICD-8 Finland
Other symptoms referable to nervous system and special senses, Laesio loquendi alia sive NUD
33.6
8.1
10
*
F20.10
ICD-10 Finland
Raise schizophrenia continuously
17.3
8.1
12
7
C03CA01
ATC
furosemide; systemic
1.7
8.1
191
1225
A28
ICPC
Limited function/disability NOS
2.0
8.0
105
557
4300A
ICD-9 Finland
Subarachnoid haemorrhage[HAEMORRHAGIA SUBARACHNOID. POST ANEURYSMA SACCULARE]
22.2
8.0
11
5
N05CF01
ATC
zopiclone; oral
1.5
7.9
280
1992
L17
ICPC
Foot/toe symptom/complaint
1.6
7.9
242
1664
R56.0
ICD-10 Finland
Febrile convulsions
7.0
7.8
18
26
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.2
7.8
74
343
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
7.6
124
710
V700A
ICD-9 Finland
General medical examination, Routine general medical examination at a health care facility
3.5
7.6
33
95
J01DA01
ATC
[U] cefalexin; systemic
1.4
7.6
644
5435
P72
ICPC
Schizophrenia
3.9
7.6
29
75
2402
FHL
External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)
5.5
7.5
21
39
A04
ICPC
Weakness/tiredness general
1.8
7.5
138
824
N01
ICPC
Headache
1.7
7.4
151
927
4340A
ICD-9 Finland
Occlusion of cerebral arteries, Cerebral thrombosis
8.4
7.3
15
18
N05AB03
ATC
perphenazine; systemic, rectal
2.7
7.3
47
177
N03AG06
ATC
tiagabine; oral
+∞
7.3
7
*
S06.0
ICD-10 Finland
Concussion
1.8
7.2
115
652
SPAT1301
SPAT
No procedures
1.5
7.2
307
2270
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.9
7.2
42
150
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.1
7.1
75
365
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
2.6
7.1
50
200
Z30.0
ICD-10 Finland
General counselling and advice on contraception
2.1
7.1
81
409
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
13.9
6.9
11
8
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.9
6.8
97
529
S60.2
ICD-10 Finland
Contusion of other parts of wrist and hand
2.3
6.8
58
257
7802X
ICD-9 Finland
General symptoms, Syncope and collapse[SYNCOPE ET COLLAPSUS NUD]
9.4
6.8
13
14
2152
FHL
Extraction, big brain
40.3
6.8
8
*
2951C
ICD-9 Finland
Schizophrenic psychoses, Disorganised type[HEBEFREENISTYYPPINEN SKITSOFRENIA,KROONINEN]
40.3
6.8
8
*
G04BD07
ATC
tolterodine; oral
2.9
6.7
39
138
L03
ICPC
Low back symptom/complaint
1.5
6.7
230
1619
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
3.3
6.7
31
95
3050A
ICD-9 Finland
Nondependent abuse of drugs, Alcohol abuse
6.5
6.6
16
25
S42.2
ICD-10 Finland
Fracture of upper end of humerus
2.7
6.6
41
153
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
3.8
6.6
26
70
P99
ICPC
Psychological disorders other
2.7
6.5
42
158
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
4.5
6.5
21
47
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.7
6.5
129
787
E950A
ICD-9 Finland
Suicide and self-inflicted poisoning by solid or liquid substances
5.7
6.5
17
30
4331A
ICD-9 Finland
Occlusion and stenosis of precerebral arteries, Carotid artery[OCCL/STENOSIS ARTERIAE CAROTIS CUM INFARCTU CEREBRI]
70.2
6.4
7
*
85100
ICD-8 Finland
Cerebral laceration and contusion, Without mention of open intracranial wound
70.2
6.4
7
*
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
3.2
6.4
31
99
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
6.3
326
2491
78259
ICD-8 Finland
Symptoms referable to cardiovascular and lymphatic system, Syncope (lipothymia) alia sive NUD
18.1
6.3
9
5
G40.59
ICD-10 Finland
Other special epileptic syndromes
+∞
6.3
6
*
N03AA03
ATC
primidone; oral
26.8
6.2
8
*
79399
ICD-8 Finland
Observation, without need for further medical care, Unspecified
5.4
6.2
17
32
SPAT1254
SPAT
Administration of medicine
1.6
6.2
145
927
N05AF03
ATC
chlorprothixene; systemic
2.9
6.1
35
122
E883A
ICD-9 Finland
Fall into hole or other opening in surface
2.4
6.1
48
205
S70.0
ICD-10 Finland
Contusion of hip
2.9
6.1
33
114
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.8
6.1
100
575
TAB00
NOMESCO Finland
Lumbar puncture
2.2
6.1
55
251
9694A
ICD-9 Finland
Poisoning by psychotropic agents, Benzodiazepine-based tranquillisers
6.7
6.0
14
21
E9509
ICD-8 Finland
Suicide and self-inflicted poisoning by solid or liquid substances, Other and unspecified solid and liquid substances
10.1
6.0
11
11
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
3.7
6.0
24
66

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
289
115
32.15
307.65
4.5
5.9
385.8
363.3
umol/l
0.83
262
101
74
20
39.20
120.19
3.0
1.8
17.4
13.0
umol/l
1.63
74
20
459
2408
2.41
46.28
2.9
2.0
173.6
211.7
u/l
0.64
448
2283
585
3827
1.97
30.31
5.8
6.6
1.2
1.2
mmol/l
3.17
546
3507
632
4264
1.95
29.71
6.5
7.0
1.2
1.2
mmol/l
2.19
533
3639
87
243
3.77
27.17
2.3
2.3
368.8
280.9
ug/l
0.20
82
226
726
5407
1.79
22.47
5.3
4.8
6.5
6.5
mmol/l
0.01
671
4952
65
182
3.71
20.22
2.8
4.0
35.3
35.0
umol/l
0.04
57
161
480
3322
1.71
18.00
5.5
6.4
—
—
—
0
0
671
5276
1.57
13.87
6.9
6.6
0.2
0.2
e9/l
0.73
590
4690
669
5275
1.56
13.52
6.2
6.2
2.1
2.0
e9/l
1.09
587
4717
651
5102
1.56
13.52
6.2
6.2
0.0
0.0
e9/l
0.58
564
4458
649
5084
1.56
13.50
6.1
6.2
0.6
0.6
e9/l
1.09
564
4441
620
4825
1.55
13.16
6.3
6.2
2.7
2.9
%
1.35
586
4529
623
4864
1.55
12.96
6.8
6.5
8.4
8.3
%
0.42
590
4604
357
2454
1.63
12.87
3.8
3.8
7.4
7.4
ph
0.68
63
451
491
3645
1.56
12.75
5.1
5.1
35.8
36.6
g/l
2.29
455
3410
641
5051
1.54
12.68
6.5
6.2
31.6
29.7
%
4.05
606
4770
716
5814
1.52
12.08
9.7
8.9
3.9
4.0
e9/l
0.27
623
5103
628
4985
1.51
11.63
6.1
6.0
53.8
55.9
%
4.23
595
4724
391
2804
1.57
11.59
2.5
2.5
53.7
56.2
u/l
0.56
365
2618
592
4660
1.50
11.31
6.4
6.3
0.6
0.7
%
0.38
561
4388
1113
10106
1.76
10.73
17.1
12.5
138.9
139.6
mmol/l
12.84
1082
9841
588
4659
1.48
10.67
5.6
6.0
9.2
11.8
umol/l
3.83
553
4405
843
7181
1.51
10.63
7.2
6.8
78.2
79.1
u/l
0.25
783
6767
152
867
1.85
10.56
4.0
5.8
1.0
1.7
mmol/l
1.18
123
693
152
873
1.84
10.33
4.0
5.8
5.8
5.8
kpa
0.13
143
846
308
2152
1.57
10.02
5.2
4.0
—
—
—
0
0
211
1346
1.68
9.94
3.3
4.4
0.8
0.8
mmol/l
0.11
197
1269
144
830
1.83
9.66
7.3
8.8
1.1
1.0
mmol/l
0.12
115
652
234
1552
1.62
9.43
3.7
3.3
395.3
560.6
ng/l
0.26
152
1031
143
837
1.80
9.12
7.1
8.7
12.8
12.8
kpa
0.04
138
807
1107
10138
1.67
9.05
17.0
12.6
4.0
3.9
mmol/l
2.04
1076
9853
205
1330
1.64
9.00
1.8
1.7
1131.8
1151.7
nmol/l
0.11
162
1023
412
3139
1.46
8.66
8.8
7.3
1.1
1.2
inr
0.42
115
973
120
684
1.83
8.34
8.0
9.1
122.8
122.3
g/l
0.11
113
666
81
404
2.07
8.31
9.7
12.3
—
—
—
0
0
20
46
4.40
8.16
2.3
4.6
203.6
167.9
umol/l
0.15
12
27
402
3079
1.45
8.12
3.7
3.1
34.5
44.1
ng/l
0.42
222
1749
381
2897
1.45
7.97
2.6
3.1
2.3
2.4
mmol/l
2.21
332
2612
429
3335
1.43
7.96
1.9
1.8
95.6
96.1
pmol/l
0.08
226
1786
125
738
1.77
7.74
5.5
8.6
1.3
1.4
mmol/l
0.24
119
699
144
890
1.70
7.57
2.6
2.4
34.3
41.3
u/l
0.47
133
748
83
440
1.95
7.22
7.9
7.1
24.6
24.3
mmol/l
0.29
77
414
123
752
1.70
6.74
7.9
9.2
95.8
95.9
%
0.04
118
733
124
760
1.70
6.73
3.4
5.3
4.8
4.8
kpa
0.06
116
734
130
817
1.66
6.42
1.9
2.8
0.2
0.2
g/l
0.20
125
776
52
243
2.19
6.36
8.8
7.1
1.4
1.2
mmol/l
0.96
43
210
287
2151
1.43
6.30
3.7
3.4
1.0
1.0
kg/l
0.25
40
304
333
2564
1.40
6.27
3.4
2.6
—
—
—
0
0
331
2560
1.39
6.04
6.2
6.8
—
—
—
0
0
124
784
1.64
5.99
6.6
10.1
—
—
—
0
0
56
285
2.01
5.53
7.8
6.3
1.0
0.9
%
0.71
51
270
90
535
1.73
5.48
2.4
3.0
92.9
152.2
ng/l
1.82
83
477
62
331
1.92
5.35
2.9
2.6
—
—
—
0
0
92
555
1.71
5.32
3.5
6.5
23.7
23.9
mmol/l
0.32
85
514
23
79
2.95
5.32
3.1
2.0
—
—
—
0
0
56
291
1.97
5.23
7.3
6.2
2.0
1.6
%
1.21
51
274
144
977
1.53
5.18
6.1
7.4
104.2
104.5
mmol/l
0.30
136
957
86
516
1.71
5.08
2.9
2.8
—
—
—
0
0
110
706
1.61
5.03
3.4
2.5
3.4
4.2
e9/l
5.03
88
600
320
3970
0.74
5.01
2.5
2.4
—
—
—
0
0
732
6490
1.30
4.95
4.7
3.9
525.1
2146.8
e6/l
0.89
15
89
78
459
1.74
4.94
6.6
5.2
—
—
—
0
0
37
171
2.20
4.72
4.3
3.0
2.5
2.4
mmol/l
0.06
26
104
83
1313
0.61
4.68
2.4
2.7
0.7
0.7
ug/l
0.51
51
753
113
747
1.56
4.57
3.7
3.9
—
—
—
0
0
285
2240
1.35
4.57
1.7
2.0
1.5
1.1
mg/l
0.42
210
1668
105
695
1.56
4.24
3.5
5.6
5.2
5.1
kpa
0.66
98
651
91
583
1.60
4.22
2.3
2.1
—
—
—
0
0
49
265
1.88
4.13
2.4
1.8
0.9
2.5
ug/l
0.78
43
233
238
1848
1.35
4.11
1.6
1.5
21.3
20.7
nmol/l
0.21
217
1626
41
209
1.99
4.10
1.1
1.9
—
—
—
0
0
103
686
1.55
4.06
3.5
5.7
7.4
7.4
ph
—
8
63
40
205
1.98
3.95
4.1
3.0
7.4
7.4
ph
0.20
35
169
108
737
1.51
3.82
2.4
2.0
—
—
—
0
0
93
616
1.55
3.77
1.5
1.4
—
—
—
0
0
42
225
1.90
3.67
1.1
1.8
5.3
13.9
e6/l
0.98
36
180
42
225
1.90
3.67
1.2
1.9
1398.2
1629.9
e6/l
0.06
37
185
108
744
1.49
3.66
2.4
2.0
—
—
—
0
0
108
747
1.49
3.59
2.4
2.0
—
—
—
0
0
1138
10890
1.40
3.56
11.0
8.9
29.3
26.8
u/l
0.32
1098
10567
41
221
1.88
3.53
1.1
1.8
3.7
3.7
mmol/l
0.18
41
209
27
125
2.18
3.49
1.8
1.6
63.8
71.4
mmol/l
0.34
21
108
106
735
1.48
3.49
2.5
1.9
—
—
—
0
0
124
891
1.43
3.40
2.7
3.4
1.8
1.7
%
0.74
111
809
525
4607
1.24
3.38
8.8
8.7
0.0
0.0
e9/l
0.58
403
3745
1090
10378
1.33
3.37
16.0
11.5
21.4
21.5
mg/l
0.04
887
7996
16
59
2.73
3.33
1.2
1.1
—
—
—
0
0
21
89
2.38
3.33
2.0
1.6
90.3
91.0
%
0.29
21
89
155
1165
1.38
3.28
1.7
1.6
—
—
—
0
0
100
695
1.48
3.26
2.5
2.0
—
—
—
0
0
102
1424
0.69
3.20
1.3
1.3
—
—
—
0
0
786
7225
1.23
3.14
4.0
3.8
10.9
10.0
mm/h
0.91
735
6751
223
1784
1.30
3.10
2.6
2.7
541.4
555.8
mosm/kgh2o
0.39
194
1517
7
12
5.86
3.02
9.6
7.9
—
—
—
0
0
185
1451
1.32
2.97
1.3
1.4
513.8
521.9
titre
0.02
32
281
214
1714
1.30
2.95
1.7
1.6
425.1
35294541.3
pmol/l
2.26
177
1479
104
746
1.43
2.90
2.1
2.3
7827.3
5364.7
u/l
0.29
47
313
46
275
1.70
2.87
2.7
2.9
—
—
—
0
0
157
1212
1.34
2.82
5.9
7.0
1.1
1.1
mmol/l
0.09
145
1140
131
984
1.37
2.81
1.7
2.1
394.8
368.2
nmol/l
0.74
123
919
881
9341
0.82
2.76
3.5
3.4
1.3
1.3
mmol/l
1.40
822
8789
62
405
1.56
2.74
1.3
1.2
0.2
1.1
u/ml
—
5
31
37
212
1.77
2.69
3.2
3.5
3.9
3.9
mmol/l
0.17
31
197
325
2766
1.23
2.68
2.7
3.2
79.2
82.5
e6/l
0.02
254
2102
922
9721
0.82
2.66
3.9
3.7
1.5
1.5
mmol/l
0.08
865
9153
195
1565
1.29
2.65
1.7
1.6
—
—
—
0
0
19
86
2.23
2.64
1.4
2.5
—
—
—
0
0
927
9762
0.82
2.60
4.0
3.8
4.7
4.7
mmol/l
0.30
880
9239
745
6881
1.20
2.58
4.7
3.9
—
—
—
0
0
283
2382
1.24
2.58
2.3
2.1
2.8
2.8
mg/l
0.06
244
2052
939
9872
0.82
2.56
4.3
4.1
2.8
2.8
mmol/l
0.08
882
9272
388
3380
1.21
2.53
3.2
3.6
68.4
74.5
e6/l
0.09
269
2280
58
856
0.66
2.46
1.4
1.4
—
—
—
0
0
266
2250
1.23
2.31
3.7
3.3
—
—
—
0
0
986
9393
1.21
2.27
5.1
4.6
1.9
1.9
mu/l
0.14
919
8797
12
47
2.57
2.27
1.2
1.4
—
—
—
0
0
6
13
4.63
2.27
1.2
1.5
—
—
—
0
0
177
1437
1.27
2.21
2.2
2.9
6.3
2.7
e6/l
1.55
98
783
44
281
1.59
2.19
4.5
4.6
—
—
—
0
0
312
2697
1.21
2.18
3.5
3.4
7.6
8.1
mmol/l
0.97
263
2333
7
19
3.70
2.15
1.3
1.3
—
—
—
0
0
146
1163
1.29
2.13
2.4
2.5
23.4
23.8
%
0.11
112
1018
231
1944
1.23
2.10
2.7
3.1
767.2
1078.8
ng/l
1.09
188
1614
172
1401
1.26
2.10
2.4
2.4
13.4
14.2
umol/l
0.68
160
1299
275
2357
1.21
2.09
4.1
4.2
96.0
92.7
%
1.56
270
2286
31
184
1.70
2.05
1.1
1.1
59.3
2442.8
iu/ml
—
7
54
7
20
3.51
2.05
1.3
16.1
—
—
—
0
0
37
232
1.61
2.00
3.2
4.6
23.5
24.5
mmol/l
0.81
32
202
158
1284
1.26
1.97
2.4
2.4
2.4
2.4
g/l
0.35
148
1189
7
21
3.35
1.96
1.6
1.2
—
—
—
0
0
339
3828
0.84
1.94
1.9
2.0
—
—
—
0
0
30
181
1.67
1.89
1.9
2.4
129.4
132.2
g/l
0.27
22
145
30
181
1.67
1.89
3.8
3.0
—
—
—
0
0
846
8004
1.17
1.88
4.3
4.0
14.0
14.5
pmol/l
6.55
785
7414
6
18
3.34
1.75
2.0
1.3
—
—
—
0
0
26
155
1.69
1.73
2.3
2.3
16.5
16.4
%
—
10
86
91
1166
0.76
1.72
1.3
1.2
—
—
—
0
0
13
61
2.14
1.72
2.7
2.9
—
—
—
0
0
13
62
2.11
1.66
1.1
1.0
—
—
—
0
0
313
2772
1.17
1.63
1.4
1.3
2.5
1.6
u/ml
0.43
74
723
83
637
1.32
1.63
4.0
3.4
1.2
1.2
mmol/l
1.06
75
546
80
611
1.33
1.63
1.3
1.2
—
—
—
0
0
15
77
1.96
1.59
1.3
1.3
—
—
—
0
0
6
20
3.01
1.58
1.0
1.1
—
—
—
0
0
281
2475
1.17
1.57
2.6
3.0
—
—
—
0
0
81
624
1.32
1.56
2.4
3.2
69.5
70.8
e9/l
0.12
69
453
946
9081
1.16
1.55
19.7
14.2
13.3
13.5
%
3.04
928
8908
272
2393
1.17
1.54
1.7
1.7
1.5
1.4
mmol/l
0.40
240
2072
13
64
2.04
1.54
1.1
1.1
—
—
—
0
0
18
100
1.81
1.53
3.9
4.0
—
—
—
0
0
51
699
0.72
1.53
1.5
1.4
—
—
—
0
0
6
21
2.87
1.50
1.2
1.4
—
—
—
0
0
23
139
1.67
1.49
1.1
1.4
—
—
—
0
0
112
907
1.26
1.48
1.3
1.2
68.7
150.6
iu/ml
2.33
34
374
136
1126
1.23
1.48
1.5
1.4
—
—
—
0
0
10
45
2.23
1.46
1.5
1.3
—
—
—
0
0
11
215
0.51
1.46
1.3
1.3
—
—
—
0
0
95
756
1.28
1.46
4.8
4.4
0.6
0.9
%
1.12
28
219
70
535
1.33
1.44
4.1
6.2
—
—
—
0
0
28
180
1.57
1.43
3.7
5.4
—
—
—
0
0
85
669
1.29
1.42
2.7
3.2
—
—
—
0
0
121
994
1.24
1.42
1.4
1.5
—
—
—
0
0
82
643
1.29
1.41
3.5
4.6
96.1
77.3
ng/l
0.70
66
585
191
2207
0.84
1.41
3.3
4.2
1.4
2.2
ug/l
2.78
173
1996
17
96
1.78
1.39
1.1
2.1
—
—
—
0
0
531
4935
1.13
1.36
3.7
3.2
0.0
0.0
estimate
0.80
96
929
5
17
2.95
1.36
1.0
1.1
—
—
—
0
0
17
97
1.76
1.35
1.2
1.4
0.3
0.5
u/ml
—
5
41
671
6329
1.13
1.34
3.1
3.2
—
—
—
0
0
10
47
2.14
1.34
1.1
1.3
143.4
150.1
nmol/l
—
10
47
21
128
1.65
1.33
3.6
3.1
0.6
1.4
%
1.06
16
107
281
2507
1.15
1.33
2.7
3.1
0.4
0.3
e6/l
0.15
218
1854
0
40
0.00
1.32
0.0
1.2
—
—
—
0
0
28
184
1.53
1.32
1.1
1.3
2.2
5.7
u/ml
—
9
82
39
275
1.43
1.32
1.2
1.4
325.3
307.4
ug/g
0.25
24
157
58
758
0.75
1.31
1.4
1.7
—
—
—
0
0
6
24
2.51
1.30
4.0
4.0
54.3
50.1
%
—
6
24
52
387
1.36
1.30
1.6
1.3
—
—
—
0
0
22
137
1.62
1.30
1.7
1.6
—
—
—
0
0
17
99
1.73
1.27
2.0
3.7
—
—
—
0
0
145
1231
1.20
1.26
1.3
1.2
—
—
—
0
0
118
982
1.22
1.25
1.1
1.2
—
—
—
0
0
28
188
1.50
1.22
1.0
1.1
—
—
—
0
0
8
37
2.17
1.21
1.1
1.4
—
—
—
0
0
43
316
1.37
1.18
1.7
2.2
1.3
1.4
g/l
0.26
37
283
10
185
0.54
1.16
1.6
1.6
—
—
—
0
0
37
266
1.40
1.15
1.3
1.3
—
—
—
0
0
1120
10956
1.18
1.15
15.5
10.5
—
—
—
0
0
5
20
2.51
1.15
6.4
7.7
—
—
—
0
0
5
20
2.51
1.15
1.0
1.1
—
—
—
0
0
5
20
2.51
1.15
1.0
1.1
—
—
—
0
0
5
20
2.51
1.15
1.0
1.1
—
—
—
0
0
45
335
1.36
1.14
1.1
1.1
7.2
6.5
u/ml
0.09
20
210
269
2422
1.14
1.12
1.8
1.7
—
—
—
0
0
7
30
2.34
1.12
1.3
1.3
—
—
—
0
0
105
877
1.21
1.10
19.0
18.4
1.1
1.2
inr
0.44
13
136
162
1410
1.17
1.08
2.6
2.7
2.4
2.4
mmol/l
0.38
140
1235
9
46
1.96
1.03
2.4
3.3
—
—
—
0
0
532
5006
1.11
1.03
3.8
3.3
0.0
0.0
estimate
0.80
95
920
11
60
1.84
1.03
1.6
1.3
—
—
—
0
0
267
2418
1.13
1.02
5.1
4.4
—
—
—
0
0
80
656
1.23
1.01
1.3
1.2
—
—
—
0
0
73
593
1.24
1.01
1.8
2.3
3.7
8.1
ug/l
4.52
57
527
16
99
1.62
1.00
1.4
1.3
—
—
—
0
0
20
131
1.54
1.00
1.9
2.3
—
—
—
0
0
7
35
2.01
1.00
3.1
2.3
—
—
—
0
0
11
61
1.81
0.98
1.2
1.3
—
—
—
0
0
213
1907
1.14
0.98
2.4
2.5
9.0
6.6
e6/l
0.99
188
1661
9
50
1.81
0.96
1.0
1.1
1544.9
1521.6
miu/ml
—
9
50
22
149
1.48
0.95
2.5
3.6
—
—
—
0
0
6
27
2.23
0.93
1.7
2.6
—
—
—
0
0
525
4959
1.10
0.92
5.2
4.4
0.0
0.0
estimate
0.50
102
953
28
201
1.40
0.92
1.4
1.1
—
—
—
0
0
74
611
1.22
0.90
1.7
1.6
288.8
298.1
mu/l
0.14
66
544
26
186
1.41
0.87
2.5
3.4
40.3
80.4
mg/l
0.58
18
150
26
186
1.41
0.87
2.5
3.4
30.8
32.7
mg/l
0.10
19
149
21
144
1.47
0.87
2.8
3.8
—
—
—
0
0
195
1753
1.13
0.86
1.2
1.3
19.3
26.4
iu/ml
0.55
59
536
13
80
1.63
0.84
1.0
1.2
—
—
—
0
0
27
196
1.39
0.84
1.1
1.1
—
—
—
0
0
6
111
0.54
0.83
1.0
1.1
—
—
—
0
0
20
283
0.70
0.81
1.2
1.1
—
—
—
0
0
20
282
0.70
0.80
1.2
1.1
—
—
—
0
0
10
58
1.73
0.79
1.8
3.3
913.2
782.3
u/ml
—
10
58
41
322
1.28
0.78
1.1
1.1
0.6
1.4
u/ml
1.04
17
166
73
614
1.20
0.77
4.6
2.5
—
—
—
0
0
27
200
1.36
0.76
5.7
3.6
16.9
27.5
mg/l
1.96
18
134
10
59
1.70
0.76
2.5
2.5
—
—
—
0
0
29
218
1.34
0.75
1.0
1.1
0.2
0.5
u/ml
—
7
67
17
116
1.47
0.74
3.5
4.0
6001.8
339.7
u/ml
0.45
17
108
50
406
1.24
0.74
2.2
2.3
—
—
—
0
0
37
468
0.78
0.73
1.4
1.4
—
—
—
0
0
7
38
1.85
0.73
1.0
1.1
—
—
—
0
0
7
38
1.85
0.73
1.1
1.2
—
—
—
0
0
244
2245
1.11
0.73
3.3
3.2
—
—
—
0
0
12
76
1.58
0.71
2.1
1.6
—
—
—
0
0
250
2308
1.10
0.70
4.4
4.1
15.9
10.6
mg/mmol
0.56
173
1522
52
428
1.22
0.69
1.9
1.7
—
—
—
0
0
90
780
1.17
0.69
1.3
1.3
168.5
231.2
u/ml
0.47
78
722
13
85
1.53
0.69
1.0
1.2
2.0
1.4
nmol/l
1.56
13
78
142
1274
1.13
0.67
2.1
2.0
—
—
—
0
0
43
348
1.24
0.67
2.2
5.0
0.3
0.3
g/l
0.04
19
176
7
43
1.63
0.67
1.7
3.4
—
—
—
0
0
247
2289
1.10
0.65
2.4
2.6
10391.4
5808.1
umol/l
0.49
211
2050
83
719
1.17
0.65
5.2
4.5
0.3
0.1
%
0.46
24
199
80
692
1.17
0.64
2.3
3.4
4.5
4.7
pmol/l
1.21
70
624
313
3330
0.92
0.63
1.6
1.6
—
—
—
0
0
39
479
0.81
0.62
1.4
1.5
—
—
—
0
0
263
2451
1.09
0.62
1.4
1.4
2.5
2.2
g/l
1.22
150
1519
23
173
1.34
0.62
1.9
1.4
—
—
—
0
0
5
30
1.67
0.61
1.6
1.2
—
—
—
0
0
16
113
1.42
0.61
1.2
2.4
—
—
—
0
0
26
200
1.31
0.61
4.0
3.8
—
—
—
0
0
0
21
0.00
0.60
0.0
1.4
—
—
—
0
0
24
183
1.32
0.59
2.0
1.6
—
—
—
0
0
29
229
1.27
0.57
1.1
1.1
8.5
7.2
u/ml
0.08
12
106
14
98
1.43
0.56
4.8
2.6
—
—
—
0
0
81
710
1.15
0.56
1.4
1.5
22.0
24.0
iu/l
0.26
70
588
236
2201
1.09
0.55
3.7
3.4
652.1
322.5
mg/l
0.38
162
1467
39
471
0.82
0.55
1.4
1.4
—
—
—
0
0
8
123
0.65
0.55
1.5
1.4
—
—
—
0
0
9
61
1.48
0.53
1.7
1.6
—
—
—
0
0
6
39
1.54
0.53
4.3
4.0
—
—
—
0
0
41
341
1.21
0.53
1.8
1.7
0.2
0.2
g/l
2.07
33
323
49
415
1.19
0.52
3.2
3.0
—
—
—
0
0
10
66
1.52
0.52
1.3
1.3
—
—
—
0
0
13
92
1.42
0.50
1.2
1.3
—
—
—
0
0
10
67
1.50
0.49
1.1
1.0
—
—
—
0
0
7
47
1.49
0.47
1.3
1.2
—
—
—
0
0
42
355
1.19
0.47
1.7
1.6
1.1
1.2
g/l
0.86
34
336
157
1696
0.92
0.47
1.5
1.5
—
—
—
0
0
77
684
1.13
0.47
5.2
4.5
0.0
0.1
%
1.03
20
170
61
533
1.15
0.46
1.4
1.4
—
—
—
0
0
22
173
1.28
0.46
1.3
1.7
0.5
0.8
g/l
1.03
15
133
43
365
1.18
0.46
1.2
1.2
1.3
1.9
u/ml
0.27
19
175
43
503
0.85
0.45
1.1
1.1
—
—
—
0
0
10
69
1.45
0.44
1.1
1.2
—
—
—
0
0
7
51
1.37
0.44
1.0
1.2
154.4
468.5
u/l
—
7
45
1169
11788
0.91
0.43
24.0
16.9
250.4
256.8
e9/l
2.90
1142
11508
11
78
1.41
0.43
3.6
8.3
12.2
11.8
%
0.12
11
78
38
322
1.19
0.43
1.2
1.1
6.1
3.2
u/ml
0.23
11
94
78
700
1.12
0.41
5.0
4.2
0.2
0.6
%
1.84
17
160
314
2997
1.06
0.41
2.3
2.0
—
—
—
0
0
0
15
0.00
0.41
0.0
2.7
—
5125.9
—
0
15
0
16
0.00
0.41
0.0
1.4
—
18.9
—
0
16
26
213
1.23
0.41
1.0
1.1
—
—
—
0
0
298
2841
1.06
0.41
3.5
2.9
—
—
—
0
0
15
114
1.32
0.40
1.4
1.3
2.5
2.6
g/l
—
10
81
15
114
1.32
0.40
1.4
1.3
7.0
6.2
g/l
—
10
83
15
114
1.32
0.40
1.4
1.3
0.3
0.4
g/l
—
10
82
10
138
0.72
0.40
1.1
1.7
—
—
—
0
0
10
138
0.72
0.40
1.1
1.7
—
—
—
0
0
10
138
0.72
0.40
1.1
1.7
—
—
—
0
0
10
138
0.72
0.40
1.1
1.7
—
—
—
0
0
21
168
1.25
0.40
1.1
1.2
—
—
—
0
0
1171
11802
0.91
0.40
24.0
16.9
6.8
6.7
e9/l
0.30
1144
11499
5
35
1.43
0.39
4.0
2.2
—
—
—
0
0
15
115
1.31
0.39
1.4
1.3
—
—
—
0
0
11
80
1.38
0.38
1.8
1.9
34.4
33.2
pg
0.50
11
80
31
261
1.19
0.38
1.4
1.6
—
—
—
0
0
5
36
1.39
0.38
2.2
1.6
—
—
—
0
0
30
252
1.20
0.38
1.0
1.1
7.2
6.3
u/ml
0.05
15
113
9
67
1.35
0.38
3.4
2.5
—
—
—
0
0
29
243
1.20
0.38
1.1
1.2
—
—
—
0
0
1171
11797
0.92
0.37
23.8
16.8
30.3
30.0
pg
4.84
1161
11657
14
107
1.31
0.37
1.2
1.3
—
—
nmol/l
—
0
0
38
328
1.16
0.36
1.2
1.2
—
—
—
0
0
10
135
0.74
0.36
2.0
2.9
5.4
8.0
u/ml
—
10
122
1172
11805
0.92
0.36
24.0
17.0
134.7
136.2
g/l
3.19
1162
11663
1171
11794
0.92
0.35
23.9
16.8
90.3
89.9
fl
2.06
1161
11657
18
144
1.25
0.35
1.2
1.2
—
—
—
0
0
15
117
1.29
0.35
1.2
1.3
0.6
0.6
nmol/l
0.06
15
110
6
43
1.40
0.35
1.7
1.7
—
—
—
0
0
274
2622
1.06
0.34
4.1
3.5
0.0
0.0
estimate
1.08
97
933
20
163
1.23
0.34
3.5
3.2
—
—
—
0
0
56
502
1.12
0.32
1.3
1.3
270.5
245.5
miu/ml
0.21
27
242
1172
11798
0.92
0.32
23.9
16.9
4.5
4.6
e12/l
7.38
1148
11501
32
368
0.87
0.31
1.3
1.1
—
—
—
0
0
7
54
1.30
0.30
34.4
35.4
6.7
7.6
ug/l
—
7
46
7
54
1.30
0.30
1.6
1.1
—
—
—
0
0
120
1123
1.08
0.30
2.8
3.5
5.4
7.6
umol/l
1.42
96
963
19
157
1.21
0.29
2.4
2.5
—
—
—
0
0
316
3049
1.05
0.29
2.3
2.3
—
—
—
0
0
34
298
1.14
0.28
4.9
8.3
—
—
—
0
0
50
452
1.11
0.27
1.3
1.6
8.2
8.4
u/l
0.04
42
364
10
77
1.30
0.26
1.7
2.0
—
—
—
0
0
99
1056
0.93
0.25
1.5
1.4
—
—
—
0
0
175
1671
1.05
0.25
1.3
1.3
3.1
9.9
u/ml
2.17
52
671
6
85
0.70
0.24
1.0
1.0
—
—
—
0
0
25
285
0.87
0.23
2.2
3.3
115.2
1434.3
u/ml
1.25
19
242
92
864
1.07
0.23
3.9
3.4
—
—
—
0
0
14
116
1.21
0.22
1.4
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
8
101
0.79
0.21
1.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
7.9
—
—
—
0
0
27
302
0.89
0.19
1.6
2.0
3.1
5.0
iu/l
—
7
117
22
193
1.14
0.19
2.2
2.4
84.7
132.8
ug/min
0.29
12
122
17
146
1.17
0.19
1.2
1.5
—
—
—
0
0
21
184
1.14
0.19
8.0
4.4
57.4
56.2
%
0.11
21
184
10
81
1.24
0.18
1.0
1.1
—
—
—
0
0
7
58
1.21
0.18
1.0
3.2
28.2
26.3
umol/l
—
7
58
7
59
1.19
0.18
1.1
1.3
—
—
—
0
0
44
407
1.08
0.17
1.7
1.7
—
—
—
0
0
184
1897
0.96
0.16
1.8
1.7
—
—
—
0
0
8
73
1.10
0.15
1.1
1.1
—
—
—
0
0
157
1518
1.04
0.15
2.1
2.6
112.3
102.1
ug/g
0.15
119
1219
28
258
1.09
0.12
1.5
3.0
5.6
7.2
umol/l
0.35
21
197
46
487
0.94
0.12
1.0
1.1
—
—
—
0
0
11
95
1.16
0.11
2.8
2.7
—
—
—
0
0
47
445
1.06
0.11
2.7
2.2
—
—
—
0
0
132
1358
0.97
0.11
1.8
1.9
—
—
—
0
0
12
135
0.89
0.10
2.1
1.7
—
—
—
0
0
5
48
1.04
0.09
1.4
2.6
—
—
—
0
0
65
626
1.04
0.09
1.7
1.7
1.6
1.3
g/l
0.44
59
585
72
696
1.04
0.08
4.5
4.3
20.0
29.9
ug/l
0.28
61
562
5
62
0.81
0.08
27.6
35.2
102.8
128.4
ug/l
—
5
53
933
9371
0.98
0.08
4.1
3.7
5.8
5.8
mmol/l
0.54
868
8700
99
1017
0.97
0.08
1.3
1.3
—
—
—
0
0
6
73
0.82
0.07
1.3
1.1
—
—
—
0
0
8
75
1.07
0.07
2.3
1.8
—
—
—
0
0
8
75
1.07
0.07
1.0
1.1
—
—
—
0
0
12
108
1.11
0.07
1.2
1.3
—
—
—
0
0
27
255
1.06
0.07
1.9
2.4
—
—
—
0
0
22
206
1.07
0.07
2.1
2.0
—
—
—
0
0
8
93
0.86
0.06
1.1
1.2
—
—
—
0
0
19
178
1.07
0.05
8.1
4.0
4.5
4.2
e9/l
0.14
19
178
20
188
1.06
0.05
1.2
1.2
—
—
—
0
0
15
139
1.08
0.05
1.0
1.1
—
—
—
0
0
19
200
0.95
0.03
1.4
1.4
12.7
19.7
u/l
0.60
12
172
78
769
1.02
0.02
2.5
2.1
10.5
12.7
nmol/l
1.44
66
678
232
2309
1.01
0.01
2.3
2.2
—
—
—
0
0
18
187
0.96
0.01
1.3
1.2
—
—
—
0
0
31
303
1.02
0.01
1.4
1.4
284.4
228.0
u/ml
0.35
16
178
36
367
0.98
0.01
1.3
1.2
—
—
—
0
0
10
96
1.04
0.00
2.9
3.3
—
—
—
0
0
10
104
0.96
0.00
1.3
1.2
—
—
—
0
0
863
8626
1.00
0.00
5.5
4.8
39.0
38.7
mmol/mol
0.38
801
8133
467
4666
1.00
0.00
4.4
4.1
—
—
—
0
0
498
4984
1.00
0.00
3.1
2.9
116.4
94.3
ug/l
0.69
470
4697
1014
10142
1.00
0.00
17.8
12.5
39.2
40.3
%
3.32
749
8173
19
187
1.02
0.00
2.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
173.6
—
0
5
0
5
0.00
0.00
0.0
2.6
—
194.6
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
35.5
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
5
57
0.88
0.00
1.0
1.0
6.6
8.8
mu/l
—
5
49
8
80
1.00
0.00
1.0
1.6
9.6
11.5
umol/l
—
8
74
10
100
1.00
0.00
1.4
1.4
17.9
34.4
nmol/l
—
10
88
0
9
0.00
0.00
0.0
1.0
—
35.7
—
0
9
7
75
0.93
0.00
2.9
3.4
—
—
—
0
0
7
69
1.01
0.00
1.4
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
5
57
0.88
0.00
1.4
1.1
112.2
199.8
iu/ml
—
5
57
0
8
0.00
0.00
0.0
2.0
—
216.1
—
0
8
5
52
0.96
0.00
1.2
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
8.0
—
—
—
0
0
6
62
0.97
0.00
2.7
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
5.8
—
0
9
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: GE_MODE – Generalized epilepsy, mode (most common among epilepsy diagnosis)

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).