No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1236 |
4. Check minimum number of eventsNone |
1236 |
5. Include endpointsNone |
1236 |
6. Filter based on genotype QC (FinnGen only) |
1236 |
Control definitions (FinnGen only)
- Control exclude
- COX_ARTHROSIS
Extra metadata
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M16
- Name in latin
- Alia coxarthrosis secundaria
Similar endpoints
↥List of similar endpoints to
Other secondary coxarthrosis
based on the number of shared cases.
Similar with more cases:
- Coxarthrosis
- Coxarthrosis [arthrosis of hip](FG)
- Arthrosis
- Finngen Rheumatological endpoints
- Artrosis, including avohilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 9231 | 4924 | 4215 |
| Only index persons | 7599 | 4223 | 3376 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.13 | 0.14 | 0.12 |
| Only index persons | 0.14 | 0.16 | 0.13 |
| Median age at first event (years) | |||
| Whole population | 57.39 | 58.73 | 55.66 |
| Only index persons | 54.94 | 56.62 | 52.85 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1236 | 691 | 545 |
| Unadjusted period prevalence (%) | 0.24 | 0.24 | 0.24 |
| Median age at first event (years) | 55.19 | 54.66 | 55.87 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1093
- Matched controls
- 10931
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
630.7
323.0
489
14
M16.1
ICD-10 Finland
Other primary coxarthrosis
261.3
323.0
562
44
M16.7
ICD-10 Finland
Other secondary coxarthrosis
16384.0
323.0
918
*
NF1AA
NOMESCO Finland
Hip X-ray examination
27.2
291.2
418
243
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
113.9
270.4
287
34
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
63.3
219.5
254
52
7152E
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, secondary[OSTEORTHROSIS SECUNDARIA,LONKKANIVEL]
+∞
211.5
196
*
L13
ICPC
Hip symptom/complaint
8.3
161.2
417
757
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
42.3
144.6
181
51
9294
FHL
Endoprosthesis replacement of the entire hip joint (eg Charnley)
402.8
144.5
142
*
M16.9
ICD-10 Finland
Coxarthrosis, unspecified
26.5
140.9
199
91
NFC20
NOMESCO Finland
Secondary implantation of hip prosthesis
232.6
140.4
142
7
NFB40
NOMESCO Finland
Primary total prosthetic replacement of hip joint using hybrid technique
102.9
139.2
151
17
NE1AA
NOMESCO Finland
Pelvis X-ray examination
14.3
137.0
245
216
M16.3
ICD-10 Finland
Other dysplastic coxarthrosis
721.1
132.5
128
*
B01AB05
ATC
enoxaparin; parenteral
5.0
126.9
581
2036
WX320
NOMESCO Finland
Spinalanesthesy
4.9
106.2
437
1306
L89
ICPC
Osteoarthrosis of hip
32.9
99.0
131
45
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
20.4
98.9
151
85
NF1DA
NOMESCO Finland
X-ray of hips
37.3
98.1
126
38
NFB60
NOMESCO Finland
Demanding prosthetic replacement of hip
116.0
97.9
105
10
M16
ICD-10 Finland
Coxarthrosis [arthrosis of hip]
15.5
78.1
132
96
NJ3NA
NOMESCO Finland
Measurement of difference in extremity lengty with X-ray
165.4
74.0
77
5
B01AF01
ATC
rivaroxaban; oral
5.0
68.2
244
588
NFC40
NOMESCO Finland
Repair of hip prosthesis by bone transplant to acetabulum
699.4
67.7
66
*
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
17.3
66.5
107
68
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
4.6
63.0
247
650
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
17.0
62.4
101
65
M16.5
ICD-10 Finland
Other post-traumatic coxarthrosis
+∞
61.0
58
*
N02AX02
ATC
tramadol; systemic, rectal
2.8
54.9
588
3245
7151E
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, LONKKANIVEL]
+∞
53.6
51
*
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
6.2
52.5
150
271
71300
ICD-8 Finland
Osteo-arthritis and allied conditions, Arthritis (arthrosis) coxae
+∞
52.5
50
*
NFB50
NOMESCO Finland
Primary total prosthetic replacement of hip joint using cement
66.7
49.7
57
9
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
14.5
49.6
85
63
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
4.3
47.1
195
529
M16.6
ICD-10 Finland
Other secondary coxarthrosis, bilateral
477.0
46.6
46
*
A07EC01
ATC
sulfasalazine; oral, rectal
4.7
46.4
173
423
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.6
46.0
520
2859
ZXA05
NOMESCO Finland
Left side
2.8
44.3
376
1740
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
15.0
43.2
73
52
M87.0
ICD-10 Finland
Idiopathic aseptic necrosis of bone
28.5
42.0
57
21
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.6
40.9
154
378
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.4
40.8
572
3443
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
6.5
40.1
109
183
M16.2
ICD-10 Finland
Coxarthrosis resulting from dysplasia, bilateral
+∞
39.8
38
*
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
8.7
39.3
87
107
Q65.0
ICD-10 Finland
Congenital dislocation of hip, unilateral
401.1
39.3
39
*
L88
ICPC
Rheumatoid/seropositive arthritis
6.2
39.1
111
197
NFC00
NOMESCO Finland
Exchange of a loose part of prosthesis in hip joint
+∞
38.8
37
*
N02BE01
ATC
paracetamol; systemic, rectal
3.2
38.6
977
7922
WX002
NOMESCO Finland
Sedation and analgesia
2.8
37.8
292
1256
M01AH05
ATC
etoricoxib; oral
2.3
37.6
700
4761
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.4
37.5
201
671
B01AX06
ATC
[U] rivaroxaban; oral
12.4
37.3
68
58
ZXA00
NOMESCO Finland
Right side
2.5
37.0
383
1943
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
8.8
37.0
81
98
M25.5
ICD-10 Finland
Pain in joint
2.5
36.6
377
1906
WZA00
NOMESCO Finland
Short statement of of health and health related matters
5.3
36.4
118
246
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
8.7
35.7
79
97
NE1BA
NOMESCO Finland
Pelvis extensive X-ray examination
34.2
35.6
46
14
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.4
35.4
188
621
N02AJ06
ATC
codeine and paracetamol; systemic
2.3
35.2
452
2545
SPAT1153
SPAT
Removal of sutures
2.3
34.7
424
2325
P01BA02
ATC
hydroxychloroquine; oral
3.8
34.5
159
468
9321
FHL
The first reartroplast due to detachment, also includes the treatment of a fracture due to detachment
347.3
34.1
34
*
M87.9
ICD-10 Finland
Osteonecrosis, unspecified
44.8
32.0
39
9
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
4.1
31.9
134
362
NFH30
NOMESCO Finland
Reduction of dislocation prosthesis of hip joint, closed
116.8
31.8
34
*
M01AH01
ATC
celecoxib; oral (coxibs)
2.6
31.7
266
1186
S18
ICPC
Laceration/cut
2.2
31.4
512
3167
NFU20
NOMESCO Finland
Removal of internal fixation device from femur
17.6
31.3
49
29
N03AX12
ATC
gabapentin; oral
2.8
30.2
226
938
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
4.1
30.2
125
333
7543A
ICD-9 Finland
Certain congenital musculoskeletal deformities, Congenital dislocation of hip[LUXATIO COXAE CONGENITA]
310.4
29.9
30
*
75560
ICD-8 Finland
Other congenital anomalies of limbs, Dislocatio congenita coxae (fixata)
+∞
29.3
28
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.6
28.4
234
1023
L28
ICPC
Limited function/disability (L)
2.7
27.8
218
927
M24.8
ICD-10 Finland
Other specific joint derangements, not elsewhere classified
26.2
27.6
38
15
NFF25
NOMESCO Finland
Cleaning of hip joint, arthroscopic
48.5
27.6
33
7
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
15.6
27.5
45
30
L04AB01
ATC
etanercept; parenteral
12.5
27.2
49
41
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.4
26.6
273
1340
WZA90
NOMESCO Finland
Other doctors statement
2.3
26.3
283
1422
NFG00
NOMESCO Finland
Arthroplasty of hip joint
138.2
25.7
27
*
X59
ICD-10 Finland
Exposure to unspecified factor
2.4
25.3
242
1140
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
3.1
25.1
146
510
B01AB04
ATC
dalteparin; parenteral
4.6
24.9
90
210
SAA02
NOMESCO Finland
Basic examination of mouth
2.0
24.7
683
5023
9964A
ICD-9 Finland
Complications peculiar to certain specified procedures, Mechanical complication of internal orthopaedic device, implant and graft
133.0
24.7
26
*
M79.6
ICD-10 Finland
Pain in limb
2.0
24.5
416
2538
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
24.3
351
2003
L04AA13
ATC
leflunomide; oral
5.8
24.1
70
128
L04AB04
ATC
adalimumab; parenteral
9.0
24.0
51
59
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
24.0
499
3287
Y83.1
ICD-10 Finland
Surgical operation with implant of artificial internal device as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
12.8
23.7
42
34
M01CB01
ATC
sodium aurothiomalate; parenteral
8.3
23.4
52
65
ZZH31
NOMESCO Finland
Bone allograft, small pieces
17.7
23.2
36
21
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.5
23.0
208
948
A02BC02
ATC
pantoprazole; systemic
1.9
22.9
717
5442
9165
FHL
Removal of osteosynthesis material
6.3
22.2
60
100
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
8.9
22.0
47
55
WX130
NOMESCO Finland
Interpleural anesthesia
+∞
21.9
21
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.0
21.8
400
2489
M13.9
ICD-10 Finland
Arthritis, unspecified
3.4
21.6
110
348
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
21.5
258
1347
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
6.1
21.1
58
99
NF1AT
NOMESCO Finland
Puncture of hip joint with ultrasound guidance
78.3
20.7
23
*
M91.1
ICD-10 Finland
Juvenile osteochondrosis of head of femur [Legg-Calvé-Perthes]
213.8
20.6
21
*
NF2AT
NOMESCO Finland
Injection to hip joint with ultrasound guidance
42.5
20.5
25
6
N02AA05
ATC
oxycodone; systemic
2.4
20.3
189
870
M17.5
ICD-10 Finland
Other secondary gonarthrosis
8.9
20.2
43
50
Y88.1
ICD-10 Finland
Sequelae of misadventures to patients during surgical and medical procedures
12.4
20.1
36
30
M45
ICD-10 Finland
Ankylosing spondylitis
8.2
20.1
45
57
M01AX05
ATC
glucosamine; oral
2.2
20.0
246
1291
7321A
ICD-9 Finland
Osteochondropathies, Juvenile osteochondrosis of hip and pelvis[COXA PLANA (LEGG-CALVô-PERTHES)]
+∞
19.8
19
*
Q65.1
ICD-10 Finland
Congenital dislocation of hip, bilateral
+∞
19.8
19
*
N03AX16
ATC
pregabalin; oral
2.0
19.3
284
1608
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
5.0
19.0
62
130
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
9.4
19.0
39
43
72211
ICD-8 Finland
Osteochondrosis, Coxae planae
+∞
18.8
18
*
H02AB06
ATC
prednisolone; systemic
1.8
18.7
524
3712
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.8
18.6
127
488
T84.8
ICD-10 Finland
Other complications of internal orthopaedic prosthetic devices, implants and grafts
67.7
17.8
20
*
NFB99
NOMESCO Finland
Other primary prosthetic replacement of hip joint
+∞
17.7
17
*
NFC50
NOMESCO Finland
Repair of hip prosthesis by bone transplant to femur and acetabulum
+∞
17.7
17
*
Q65.80
ICD-10 Finland
Congenital dysplastic hip or acetabulum, unilateral
+∞
17.7
17
*
NFA30
NOMESCO Finland
Exploration of hip joint, arthroscopic
182.7
17.6
18
*
A28
ICPC
Limited function/disability NOS
2.3
17.1
178
862
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
4.4
17.1
62
146
S73.0
ICD-10 Finland
Dislocation of hip
32.0
17.1
22
7
NFL22
NOMESCO Finland
Myotomy or tenotomy of hip or thigh
+∞
16.7
16
*
NFE15
NOMESCO Finland
Plastic repair of capsule or ligament of hip joint
91.4
16.6
18
*
M17.4
ICD-10 Finland
Other secondary gonarthrosis, bilateral
20.4
16.5
24
12
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.6
16.4
125
513
M01AC06
ATC
meloxicam; systemic, rectal
1.8
16.3
411
2783
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.5
15.9
128
543
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
3.4
15.7
78
242
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
3.1
15.6
90
312
A02BC05
ATC
esomeprazole; systemic
1.7
15.6
438
3053
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
15.5
330
2106
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
5.1
15.5
49
100
M19.2
ICD-10 Finland
Other secondary arthrosis
9.1
15.5
32
36
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.2
15.3
81
264
SPAT1263
SPAT
Sampling
1.7
15.2
445
3128
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.2
14.9
157
763
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
2.2
14.6
157
767
TNF11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in hip joint
81.2
14.6
16
*
M87.3
ICD-10 Finland
Other secondary osteonecrosis
81.2
14.6
16
*
M01AB05
ATC
diclofenac; systemic, rectal
1.7
14.5
703
5668
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.8
14.5
96
363
M05BA04
ATC
alendronic acid; oral
2.6
14.4
113
472
M01AE03
ATC
ketoprofen; systemic, rectal
1.7
14.1
421
2961
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.6
14.1
107
437
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.8
14.0
294
1858
M01AH02
ATC
rofecoxib; oral
2.1
13.9
161
813
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.8
13.9
266
1631
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
4.9
13.9
45
95
S70.0
ICD-10 Finland
Contusion of hip
3.8
13.7
58
159
NFJ62
NOMESCO Finland
Internal fixation of fracture of other parts of femur with plate
14.9
13.6
22
15
9322
FHL
Subsequent reartroplast due to detachment also includes treatment of the fracture due to detachment
+∞
13.6
13
*
NEK20
NOMESCO Finland
Fenestration or forage of bone of pelvis
+∞
13.6
13
*
9292
FHL
Femoral osteotomy
+∞
13.6
13
*
L04AB06
ATC
golimumab; parenteral
11.1
13.5
25
23
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.7
13.2
94
372
M01AB55
ATC
diclofenac, combinations; oral
2.6
13.2
97
391
J01DB01
ATC
cefalexin; oral
1.7
13.0
853
7356
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.5
12.9
109
471
R4110
NOMESCO Finland
Physiotherapy
1.7
12.9
296
1916
Z01.2
ICD-10 Finland
Dental examination
1.6
12.8
409
2909
1220
FHL
Arthroscopy
3.5
12.7
58
170
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
5.0
12.6
40
83
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
10.2
12.5
24
24
A02BC01
ATC
omeprazole; systemic
1.7
12.5
309
2042
A02BC03
ATC
lansoprazole; oral
1.7
12.5
327
2199
M70.6
ICD-10 Finland
Trochanteric bursitis
2.2
12.3
135
665
M96.6
ICD-10 Finland
Fracture of bone following insertion of orthopaedic implant, joint prosthesis, or bone plate
21.5
12.0
17
8
NG1DA
NOMESCO Finland
X-ray of knees
6.1
12.0
32
54
M01AE02
ATC
naproxen; oral, rectal
1.6
12.0
572
4490
M01AX17
ATC
nimesulide; oral
1.7
12.0
272
1751
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
11.9
123
589
SDA02
NOMESCO Finland
Parodonthologic therapy
1.7
11.9
326
2216
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
5.5
11.8
34
63
Y79.2
ICD-10 Finland
Orthopaedic devices associated with adverse incidents, prosthetic and other implants, materials and accessory devices
30.4
11.7
15
5
NH3EA
NOMESCO Finland
Feet X-ray examination with load
4.7
11.6
39
86
B01AX05
ATC
fondaparinux; parenteral
11.2
11.6
21
19
SAA03
NOMESCO Finland
Extended examination of mouth
1.6
11.5
377
2683
NFC99
NOMESCO Finland
Other secondary prosthetic replacement in hip joint, other or unspecified
121.2
11.4
12
*
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
3.8
11.4
47
127
M15
ICD-10 Finland
Polyarthrosis
3.1
11.3
64
218
N02AC04
ATC
dextropropoxyphene; oral
3.2
11.3
59
192
NF3AA
NOMESCO Finland
Femur X-ray examination
5.6
11.2
32
59
SPAT1229
SPAT
Assessment of need for aid
2.4
11.2
96
420
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.6
11.2
527
4093
M48.0
ICD-10 Finland
Spinal stenosis
2.1
11.1
133
679
J01FF01
ATC
clindamycin; systemic
1.7
11.1
287
1909
E870A
ICD-9 Finland
Accidental cut, puncture, perforation or haemorrhage during medical care
7.2
11.1
26
37
7140B
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SERONEGATIVA]
14.0
11.0
18
13
NE1DG
NOMESCO Finland
Pelvic, hip and femur very extensive MRI examination with high intensity magnet
14.0
11.0
18
13
L17
ICPC
Foot/toe symptom/complaint
1.7
10.9
270
1775
WX110
NOMESCO Finland
Local anesthesy
1.6
10.9
688
5709
L04AA01
ATC
[U] ciclosporin; systemic
5.5
10.8
31
58
L08
ICPC
Shoulder symptom/complaint
1.8
10.6
206
1257
NFK30
NOMESCO Finland
Angulation, rotation or displacement osteotomy of femur
60.6
10.6
12
*
M91.2
ICD-10 Finland
Coxa plana
60.6
10.6
12
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.1
10.6
127
650
72210
ICD-8 Finland
Osteochondrosis, Epiphyseolysis capitis femoris
32.8
10.3
13
*
L15
ICPC
Knee symptom/complaint
1.7
10.2
215
1344
WX720
NOMESCO Finland
Own respiration
3.1
10.2
54
178
WX306
NOMESCO Finland
Lumbar epidural anesthesy
2.9
10.2
60
213
J01CA04
ATC
amoxicillin; systemic
1.6
10.1
813
7073
S72.3
ICD-10 Finland
Fracture of shaft of femur
8.5
10.1
21
25
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
6.5
10.0
25
39
SPAT1301
SPAT
No procedures
1.6
10.0
322
2265
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.2
9.9
50
159
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
16.9
9.9
15
9
ZSN00
NOMESCO Finland
Procedure related to previous procedure classified in chapter N
16.9
9.9
15
9
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
8.2
9.8
21
26
A46
ICD-10 Finland
Erysipelas
1.9
9.6
149
842
NHG20
NOMESCO Finland
Fusion of talocrural joint
11.5
9.6
17
15
9407
FHL
Osteotomy of the upper femur
100.8
9.4
10
*
NFK99
NOMESCO Finland
Other operation on bone of femur
100.8
9.4
10
*
M16.4
ICD-10 Finland
Post-traumatic coxarthrosis, bilateral
+∞
9.4
9
*
NFK70
NOMESCO Finland
Bone transport operation of femur
+∞
9.4
9
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
9.4
167
988
NF1AA
SPAT
NA
4.3
9.3
33
78
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
9.3
139
773
M05BX04
ATC
denosumab; parenteral
2.7
9.3
63
244
M01AH03
ATC
valdecoxib; oral
2.5
9.3
75
318
J01MA02
ATC
ciprofloxacin; systemic
1.5
9.2
392
2933
X58
ICD-10 Finland
Exposure to other specified factors
1.9
9.2
138
771
J04AB02
ATC
rifampicin; systemic
6.3
9.1
23
37
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.4
9.0
75
325
N06AA09
ATC
amitriptyline; systemic
2.0
9.0
112
582
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
9.0
296
2080
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
4.5
8.9
30
68
7152F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, secondary[OSTEORTHROSIS SECUNDARIA,POLVI]
12.6
8.9
15
12
M01AE01
ATC
ibuprofen; systemic, rectal
1.6
8.9
920
8342
R06.0
ICD-10 Finland
Dyspnoea
1.6
8.8
245
1651
R50.9
ICD-10 Finland
Fever, unspecified
1.9
8.8
142
814
M05BA07
ATC
risedronic acid; oral
3.2
8.7
44
141
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
8.7
594
4895
NFU00
NOMESCO Finland
Removal of partial prosthesis from hip joint, other or unspecified
50.4
8.7
10
*
ACC51
NOMESCO Finland
Release of median nerve
2.3
8.6
82
378
L04AB05
ATC
certolizumab pegol; parenteral
11.7
8.6
15
13
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
11.7
8.6
15
13
S73.1
ICD-10 Finland
Sprain and strain of hip
11.7
8.6
15
13
J01DA01
ATC
[U] cefalexin; systemic
1.5
8.6
633
5295
L90
ICPC
Osteoarthrosis of knee
2.5
8.5
67
281
L04AX01
ATC
azathioprine; systemic
2.7
8.4
55
209
75561
ICD-8 Finland
Other congenital anomalies of limbs, Praeluxatio congenita coxae (non fixata, fenomeno Ortolani positivo)
90.7
8.4
9
*
71239
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides NUD
6.8
8.4
20
30
WX704
NOMESCO Finland
Intubation
2.2
8.3
83
394
N02AJ13
ATC
tramadol and paracetamol; systemic
4.1
8.3
31
78
WX111
NOMESCO Finland
Local infiltration anesthesia
3.4
8.3
38
114
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
33.6
8.1
10
*
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
3.1
8.1
43
144
WX402
NOMESCO Finland
General anaesthesia
1.7
8.0
169
1053
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
8.0
409
3159
Y89.9
ICD-10 Finland
Sequelae of unspecified external cause
6.3
8.0
20
32
T84.9
ICD-10 Finland
Unspecified complication of internal orthopaedic prosthetic device, implant and graft
22.2
8.0
11
5
WX212
NOMESCO Finland
Femoral plexus blockade
4.2
8.0
29
71
K02.1
ICD-10 Finland
Caries of dentine
1.4
8.0
532
4330
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
7.9
682
5832
S32.4
ICD-10 Finland
Fracture of acetabulum
7.8
7.9
17
22
7148X
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Other specified inflammatory polyarthropathies
13.1
7.9
13
10
L04AA11
ATC
[U] etanercept; parenteral
10.9
7.8
14
13
318
Kela drug reimbursment
Teriparatide
15.1
7.7
12
8
S72.9
ICD-10 Finland
Fracture of femur, part unspecified
15.1
7.7
12
8
SPAT1255
SPAT
Intravenous administration of medicine
2.3
7.7
71
324
Z50.1
ICD-10 Finland
Other physical therapy
2.4
7.7
62
264
TNC11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in elbow joint
18.5
7.6
11
6
71200
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Juvenile rheumatoid arthritis
18.5
7.6
11
6
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
8.1
7.6
16
20
RT271
NOMESCO Finland
NA
25.2
7.6
10
*
NFJ50
NOMESCO Finland
Internal fixation of fracture of neck of femur with nail or screw
10.1
7.5
14
14
M04AA01
ATC
allopurinol; systemic
1.8
7.5
135
800
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
7.5
318
2355
KMAK
NOMESCO Finland
NA
1.4
7.5
492
3978
J01MA12
ATC
levofloxacin; systemic
1.6
7.4
186
1215
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.4
7.4
545
4499
9051A
ICD-9 Finland
Late effects of musculoskeletal and connective tissue injuries, Late effect of fracture of spine and trunk without mention of spinal cord lesion
80.6
7.4
8
*
NFH10
NOMESCO Finland
Reduction of dislocation of hip joint, closed
80.6
7.4
8
*
M87.8
ICD-10 Finland
Other osteonecrosis
80.6
7.4
8
*
B01AE05
ATC
ximelagatran; oral
80.6
7.4
8
*
WX725
NOMESCO Finland
Noninvasive ventilation
2.5
7.4
56
233
TNG10
NOMESCO Finland
Puncture of knee
5.3
7.4
21
40
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
3.7
7.4
30
82
NG2CA
NOMESCO Finland
X-ray of patella with specialised projection
13.5
7.4
12
9
9403
FHL
Adductorotomy
+∞
7.3
7
*
72219
ICD-8 Finland
Osteochondrosis, Coxae juvenilis NUD
+∞
7.3
7
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
7.2
172
1108
L04AA17
ATC
[U] adalimumab; parenteral
15.9
7.2
11
7
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
7.2
288
2104
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
3.4
7.2
32
95
NFJ64
NOMESCO Finland
Other internal fixation of fracture of other parts of femur
30.2
7.2
9
*
SPAT1216
SPAT
Assessment of functional ability
1.7
7.1
151
941
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
20.2
7.1
10
5
8200A
ICD-9 Finland
Fracture of neck of femur, Transcervical fracture, closed
20.2
7.1
10
5
NDL52
NOMESCO Finland
Tenosynovectomy of hand
8.0
7.1
15
19
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
1.8
7.1
116
668
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
3.3
7.1
33
101
7200A
ICD-9 Finland
Ankylosing spondylitis and other inflammatory spondylopathies, Ankylosing spondylitis
12.1
7.1
12
10
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
5.7
7.1
19
34
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
7.1
368
2840
M02AA07
ATC
piroxicam; topical
1.4
7.1
369
2849
M06
ICD-10 Finland
Other rheumatoid arthritis
10.1
7.0
13
13
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.6
7.0
47
183
WX702
NOMESCO Finland
Supraglottic ventilation device
2.3
7.0
62
280
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
6.9
451
3625
SPAT1212
SPAT
Extensive examination of musculoskeletal system
2.1
6.9
80
405
M54.5
ICD-10 Finland
Low back pain
1.5
6.9
302
2246
-1
NOMESCO Finland
NA
1.5
6.9
298
2214
H02AB04
ATC
methylprednisolone; systemic
1.7
6.9
153
965
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
6.9
528
4370
L75
ICPC
Fracture: femur
4.8
6.9
21
44
A50
ICPC
General and Unspecified, Medication/prescr/renewal
3.0
6.9
39
135
M01AE11
ATC
tiaprofenic acid; oral, rectal
2.6
6.8
48
191
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
3.7
6.8
28
78
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.2
6.8
68
325
M54.4
ICD-10 Finland
Lumbago with sciatica
1.7
6.8
154
981
NE1BM
NOMESCO Finland
Pelvic, hip and femur MRI examination with 3 Tesla magnet
40.3
6.8
8
*
M87.1
ICD-10 Finland
Osteonecrosis due to drugs
16.8
6.7
10
6
9314
FHL
Total knee endoprosthesis (also includes patellar part)
16.8
6.7
10
6
L04AC07
ATC
tocilizumab; parenteral
16.8
6.7
10
6
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
6.7
404
3198
B01AB10
ATC
tinzaparin; parenteral
2.1
6.7
71
345
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
6.7
194
1313
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
6.7
139
863
SPAT1254
SPAT
Administration of medicine
1.7
6.7
139
863
M03BX02
ATC
tizanidine; oral
1.4
6.7
602
5117
NDG30
NOMESCO Finland
Fusion of wrist, total
7.9
6.6
14
18
NBB10
NOMESCO Finland
Primary partial prosthetic replacement of humero-scapular joint not using cement, other or unspecified
7.9
6.6
14
18
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
6.6
324
2463
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
3.7
6.6
27
75
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
3.4
6.6
30
91
E883A
ICD-9 Finland
Fall into hole or other opening in surface
2.4
6.6
55
239
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.0
6.6
77
393
Y84
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.8
6.5
20
42
SPAT1325
SPAT
Vaccination
1.4
6.5
328
2505
M15.8
ICD-10 Finland
Other polyarthrosis
4.2
6.5
23
56
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.5
6.5
224
1581
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
3.3
6.5
30
92
L99
ICPC
Musculoskeletal disease other
3.5
6.4
28
82
NG1EA
NOMESCO Finland
Knee X-ray examination with wrench
4.7
6.4
20
43
NB1AD
NOMESCO Finland
Shoulder CT examination
4.1
6.4
23
57
SPAT1231
SPAT
Assessment of adjustments needed in living environment
3.7
6.4
26
72
H05AA02
ATC
teriparatide; parenteral
14.4
6.4
10
7
9311
FHL
Knee cleansing surgery (synovectomy, debridement)
14.4
6.4
10
7
NG2AA
NOMESCO Finland
Patella X-ray examination
3.1
6.4
33
110
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
6.3
151
970
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
3.0
6.3
33
111
9503
FHL
Tendon or tendon sheath cleansing surgery (tenosynovectomy)
11.1
6.3
11
10
L50
ICPC
Musculoskeletal, Medication/prescr/renewal
11.1
6.3
11
10
7334B
ICD-9 Finland
Other disorders of bone and cartilage, Aseptic necrosis of bone[NECROSIS ASEPTICA CAPITIS ET COLLI FEMORIS]
+∞
6.3
6
*
Q65.81
ICD-10 Finland
Congenital dysplastic hip or acetabulum, bilateral
+∞
6.3
6
*
NFC30
NOMESCO Finland
Repair of hip prosthesis by bone transplant to femur
+∞
6.3
6
*
Q65.2
ICD-10 Finland
Congenital dislocation of hip, unspecified
+∞
6.3
6
*
NFS10
NOMESCO Finland
Incision and debridement of infection of hip joint
+∞
6.3
6
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
6.3
71
359
M47.9
ICD-10 Finland
Spondylosis, unspecified
2.9
6.2
36
128
R60.0
ICD-10 Finland
Localized oedema
1.8
6.2
106
621
NHG22
NOMESCO Finland
Fusion of subtalar joint
7.7
6.1
13
17
VALMI
NOMESCO Finland
NA
1.5
6.1
218
1548
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
4.9
6.1
18
37
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
6.1
201
1403
C08CA01
ATC
amlodipine; oral
1.4
6.0
344
2681
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.6
6.0
163
1085
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.4
6.0
49
212
E66.8
ICD-10 Finland
Other obesity
2.4
6.0
49
212
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
748
4519
2.66
60.10
4.9
4.0
—
—
—
0
0
963
7399
2.37
34.60
7.8
4.1
14.7
12.4
mm/h
4.79
914
6805
91
230
4.19
32.70
1.7
1.6
22262.8
14394.6
e6/l
0.50
63
171
76
181
4.41
29.48
2.2
1.5
—
—
—
0
0
55
119
4.79
24.00
1.5
1.7
62.0
58.3
%
0.23
31
79
87
268
3.42
23.46
1.4
1.4
—
—
—
0
0
765
5806
1.83
22.72
12.6
9.2
4.2
4.1
e9/l
0.79
696
5090
610
4385
1.77
21.17
6.0
4.8
34.7
35.5
g/l
2.50
575
4067
951
7852
1.92
20.18
10.8
7.6
79.8
78.6
u/l
0.33
914
7353
673
5044
1.73
19.58
7.8
6.7
1.2
1.2
mmol/l
0.03
585
4233
574
4127
1.73
19.31
2.7
2.2
79.7
77.6
nmol/l
0.89
524
3677
652
4879
1.71
18.76
5.4
3.6
0.0
0.0
estimate
0.00
122
899
659
4952
1.71
18.62
5.4
3.6
0.0
0.0
estimate
0.80
123
869
621
4612
1.70
18.16
7.1
5.9
1.2
1.2
mmol/l
0.11
580
4168
364
2333
1.79
18.06
2.5
2.4
—
—
—
0
0
650
4900
1.69
17.86
7.0
4.9
0.0
0.0
estimate
0.50
125
906
213
1160
2.01
17.41
6.6
8.0
1.5
1.2
mmol/l
0.71
171
917
213
1161
2.01
17.36
6.6
8.0
5.1
5.1
kpa
0.47
206
1111
213
1161
2.01
17.36
6.6
8.0
12.2
12.0
kpa
0.20
207
1113
1115
9925
2.26
16.59
23.2
14.3
22.4
24.5
mg/l
1.43
997
7854
684
5352
1.62
15.23
6.5
6.4
10.7
11.5
umol/l
1.32
646
5081
804
6551
1.65
15.17
5.5
4.4
3165.7
2538.5
e6/l
—
7
99
134
648
2.20
14.89
6.9
7.8
24.3
24.6
mmol/l
0.30
127
609
265
1635
1.79
14.54
1.3
1.2
36.5
11.5
u/ml
2.72
98
613
734
5902
1.60
14.11
5.5
4.8
6.7
6.8
mmol/l
0.35
691
5558
145
761
2.03
12.97
3.4
2.8
10.4
10.7
g/l
0.40
140
692
377
2630
1.62
12.91
2.8
2.7
1857.8
6036.6
umol/l
2.46
332
2276
115
555
2.18
12.82
8.0
11.2
—
—
—
0
0
354
2440
1.63
12.69
2.8
2.1
3.3
3.1
mg/l
0.56
314
2065
166
932
1.90
12.19
2.3
2.2
381.2
368.0
nmol/l
0.11
150
852
153
842
1.93
11.93
1.7
2.8
66.6
66.6
g/l
0.01
136
766
244
1559
1.70
11.59
3.0
2.4
11.2
13.1
umol/l
4.58
226
1441
434
3220
1.54
11.04
2.7
2.5
60.4
57.5
u/l
0.29
400
2973
34
93
3.73
11.01
1.5
1.3
122036.5
86978.6
e6/l
0.12
22
65
184
1118
1.76
10.40
2.8
2.6
1.9
1.8
%
0.45
159
1003
31
88
3.59
9.54
1.5
1.5
37.2
31.1
%
0.29
15
59
16
26
6.22
9.47
1.4
1.5
36.6
26.8
%
—
10
16
68
300
2.34
9.41
1.6
1.6
0.0
0.1
iu/ml
1.01
16
56
144
838
1.81
9.38
3.1
2.9
173.7
196.2
ng/l
0.35
130
764
129
727
1.86
9.32
1.5
1.6
—
—
—
0
0
251
1701
1.60
9.29
1.3
1.3
43.3
34.5
iu/ml
0.48
97
553
220
1445
1.64
9.25
3.0
2.4
2.2
2.3
g/l
2.04
209
1337
431
3286
1.48
9.24
3.4
3.3
31.2
32.6
u/l
0.51
412
3136
931
8238
1.53
9.17
26.1
17.5
13.9
13.7
%
3.63
923
8057
466
3616
1.46
9.10
4.3
3.1
—
—
—
0
0
1121
10395
1.84
8.97
23.3
16.5
139.3
139.7
mmol/l
5.61
1103
10114
1123
10425
1.84
8.87
23.5
16.6
4.0
4.0
mmol/l
0.28
1103
10131
201
1313
1.63
8.60
6.3
5.4
1.0
1.0
mmol/l
0.44
188
1213
133
777
1.80
8.55
2.9
2.6
68.1
65.5
ml/min/173m2
0.28
57
328
205
1355
1.61
8.35
3.0
2.4
21.2
22.7
%
0.91
155
1151
479
3787
1.43
8.26
6.1
3.8
—
—
—
0
0
353
2635
1.48
8.24
6.4
3.9
0.0
0.0
estimate
1.08
120
882
510
4108
1.41
7.79
3.3
2.7
132.3
138.0
ug/l
0.22
470
3769
364
2769
1.45
7.60
3.6
3.0
0.2
0.5
e6/l
2.47
293
2085
42
164
2.62
7.57
1.2
1.3
—
—
—
0
0
287
2089
1.49
7.51
2.7
2.5
4.6
6.0
e6/l
0.85
260
1844
401
3118
1.42
7.39
2.1
2.2
274.3
221.6
u/l
0.26
372
2927
232
1621
1.53
7.38
2.0
1.9
—
—
—
0
0
21
55
3.87
7.27
1.8
1.8
—
—
—
0
0
79
411
1.99
7.26
2.6
2.0
2.2
2.0
ug/l
0.04
68
367
295
2180
1.46
7.11
6.2
3.9
1.0
1.0
kg/l
0.15
39
304
46
194
2.42
7.09
3.3
3.5
4.4
4.4
e9/l
0.04
46
194
151
967
1.64
6.95
2.0
2.2
0.2
0.2
g/l
0.96
142
913
47
204
2.36
6.81
3.6
3.8
60.1
57.9
%
0.51
47
204
65
324
2.06
6.73
2.1
1.9
—
—
—
0
0
261
1907
1.47
6.62
1.8
1.7
1262.1
1212.1
nmol/l
0.35
195
1434
157
1039
1.59
6.31
3.7
3.4
—
—
—
0
0
996
9165
1.45
6.08
5.0
4.7
1.9
2.3
mu/l
0.88
918
8323
1134
10732
1.69
6.03
16.3
10.5
25.5
26.4
u/l
0.94
1100
10350
168
1146
1.54
5.91
2.0
1.8
—
—
—
0
0
57
288
2.03
5.73
1.2
1.2
—
—
—
0
0
168
1154
1.53
5.72
2.0
1.8
—
—
—
0
0
311
2405
1.39
5.68
1.6
1.5
21.1
20.9
nmol/l
0.06
265
2030
72
399
1.85
5.54
1.5
2.3
3.9
3.7
g/l
0.52
41
297
72
399
1.85
5.54
1.5
2.3
—
—
—
0
0
72
399
1.85
5.54
1.5
2.3
7.6
7.3
g/l
0.54
43
308
131
859
1.59
5.48
6.9
7.4
11.2
9.7
mmol/l
1.33
125
813
223
1641
1.44
5.38
3.3
3.3
0.8
0.8
mmol/l
0.96
203
1538
162
1122
1.51
5.31
4.2
4.4
253.7
253.2
u/l
0.01
154
1060
5
0
+∞
5.21
1.6
0.0
30.8
—
mg/l
—
5
0
226
1684
1.42
5.07
3.5
2.6
0.9
1.1
e6/l
0.96
138
953
121
797
1.57
4.97
4.3
3.6
93.8
85.7
ng/l
0.40
106
697
19
61
3.15
4.92
1.8
2.0
16.3
14.4
%
0.20
11
23
77
460
1.72
4.65
1.5
2.0
1.7
1.5
g/l
0.41
67
401
85
522
1.67
4.64
8.3
9.9
25.2
24.5
mmol/l
1.23
78
491
55
298
1.89
4.58
2.1
1.5
—
—
—
0
0
55
301
1.87
4.45
1.7
1.6
1.2
1.2
g/l
0.32
55
288
1155
11093
1.63
4.38
33.0
21.0
254.5
249.3
e9/l
1.81
1142
10801
176
1291
1.42
4.29
28.1
24.0
1.3
1.3
inr
0.11
24
161
1155
11099
1.62
4.29
33.0
21.0
4.4
4.5
e12/l
16.53
1141
10776
1155
11099
1.62
4.29
33.1
21.1
7.0
6.7
e9/l
4.22
1141
10775
1155
11102
1.62
4.25
33.3
21.1
131.5
135.4
g/l
15.41
1147
10918
417
3496
1.29
4.21
3.8
3.5
2.4
2.4
mmol/l
0.02
369
3050
64
374
1.75
4.20
1.5
2.4
3.1
3.1
g/l
0.11
41
300
21
79
2.69
4.17
1.2
1.1
—
—
—
0
0
26
109
2.42
4.16
1.1
1.2
60.7
52.6
u/l
0.33
18
79
279
2227
1.33
4.02
1.6
1.7
1.5
1.1
mg/l
1.91
219
1707
462
3945
1.27
3.98
3.9
3.6
30.6
47.8
ng/l
1.03
330
2782
63
373
1.73
3.97
1.5
2.3
9.7
10.5
g/l
0.79
48
322
15
49
3.09
3.81
1.9
2.0
—
—
—
0
0
248
1961
1.33
3.80
3.8
3.8
356.7
378.3
ng/l
0.06
208
1548
59
350
1.72
3.71
3.9
2.9
—
—
—
0
0
51
291
1.78
3.66
1.8
1.6
0.2
0.2
g/l
0.09
51
279
484
4188
1.26
3.65
2.1
2.0
93.3
94.9
pmol/l
0.29
240
2146
18
68
2.67
3.57
1.1
1.2
—
—
—
0
0
18
68
2.67
3.57
1.1
1.2
—
—
—
0
0
384
3244
1.27
3.53
4.0
3.9
10.6
7.9
mg/mmol
0.62
243
1993
997
9402
1.31
3.49
6.2
5.8
39.2
40.0
mmol/mol
2.30
932
8672
649
5831
1.24
3.41
2.7
2.8
—
—
—
0
0
150
1127
1.38
3.20
2.3
2.2
186.0
132.7
ug/g
0.52
115
893
10
28
3.59
3.20
2.4
3.0
121.3
33.1
au/ml
—
5
6
827
7657
1.24
3.17
4.1
4.0
14.9
14.8
pmol/l
0.41
754
6930
200
1573
1.32
3.16
1.9
2.0
30.2
29.6
s
0.87
192
1518
31
158
1.99
3.16
3.9
3.9
2.2
1.5
%
0.22
23
129
964
9089
1.28
3.12
24.3
15.5
39.2
39.7
%
0.98
620
6362
353
2991
1.25
3.11
3.0
2.9
1413.1
1215.8
ng/l
0.55
310
2524
20
86
2.35
3.09
1.1
1.2
—
—
—
0
0
20
86
2.35
3.09
1.3
1.2
—
—
—
0
0
328
2762
1.26
3.04
1.5
1.7
1.4
1.4
mmol/l
0.02
275
2301
44
257
1.74
2.97
1.3
1.3
—
—
—
0
0
375
3220
1.24
2.90
3.2
3.1
6.9
7.5
mmol/l
2.26
315
2693
45
269
1.70
2.82
1.4
1.2
1.5
3.5
u/ml
—
6
45
146
1117
1.35
2.79
4.5
4.3
18.2
25.7
ug/l
0.20
121
921
253
2088
1.27
2.77
1.3
1.2
1.0
1.5
u/ml
0.90
69
540
122
909
1.38
2.76
4.8
3.4
2.2
2.0
mmol/l
0.17
101
725
37
211
1.78
2.73
6.8
5.9
312.0
508.2
iu/ml
—
8
28
13
49
2.67
2.62
1.2
1.2
—
—
—
0
0
85
600
1.45
2.61
1.5
1.4
—
—
—
0
0
15
63
2.40
2.47
1.5
1.7
0.9
6.7
u/l
—
7
37
14
57
2.47
2.45
1.2
1.4
—
—
—
0
0
14
57
2.47
2.45
1.2
1.4
—
—
—
0
0
37
220
1.70
2.40
2.5
2.1
127.4
129.2
g/l
0.17
27
160
20
97
2.08
2.38
1.7
2.2
—
—
—
0
0
8
22
3.65
2.36
1.1
1.1
—
—
—
0
0
14
59
2.39
2.29
1.0
1.0
—
—
—
0
0
6
13
4.63
2.27
1.0
1.6
—
—
—
0
0
144
1144
1.29
2.15
2.9
2.7
7.0
8.6
umol/l
0.77
125
1004
36
220
1.66
2.14
1.2
1.4
—
—
—
0
0
24
131
1.85
2.09
2.5
2.4
33.2
32.5
pg
0.25
24
131
17
83
2.06
2.01
1.1
1.1
—
43.4
—
0
5
709
6614
1.17
1.98
3.4
3.2
63.0
51.4
u/l
1.33
649
6143
51
346
1.49
1.97
1.7
2.6
0.3
1.3
g/l
1.85
45
308
7
21
3.35
1.96
1.1
1.0
—
—
—
0
0
154
1249
1.27
1.96
10.6
6.8
—
—
—
0
0
17
84
2.04
1.96
1.1
1.1
—
68.0
—
0
7
8
27
2.98
1.93
1.8
1.6
—
—
—
0
0
33
203
1.64
1.93
1.4
1.2
73.3
50.6
u/ml
—
5
16
81
603
1.37
1.91
1.7
1.7
—
—
—
0
0
18
92
1.97
1.90
1.9
1.8
—
—
—
0
0
7
22
3.19
1.88
1.1
1.3
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
10
40
2.51
1.84
3.7
2.3
158.1
122.3
%
—
10
40
47
319
1.49
1.83
1.7
2.3
39.0
37.5
g/l
0.98
38
281
90
686
1.34
1.83
1.7
1.8
—
—
—
0
0
82
618
1.35
1.80
3.3
3.4
1.6
1.9
mmol/l
0.25
61
471
11
47
2.35
1.78
1.3
1.4
—
—
—
0
0
11
47
2.35
1.78
1.3
1.4
—
—
—
0
0
10
41
2.45
1.75
6.5
4.3
—
—
—
0
0
85
647
1.34
1.75
3.3
3.4
5.2
5.2
kpa
0.05
80
609
189
1590
1.22
1.75
3.7
2.8
3.4
2.2
e6/l
0.55
101
862
25
147
1.72
1.75
1.6
1.4
—
—
—
0
0
12
55
2.19
1.67
1.1
1.2
31.1
49.3
pmol/l
—
5
17
222
1913
1.20
1.61
3.3
3.0
2.5
2.5
mmol/l
1.53
204
1692
47
330
1.44
1.58
1.3
3.4
44.5
69.8
mg/l
0.53
40
267
47
330
1.44
1.58
1.3
3.4
22.1
40.5
mg/l
1.30
40
268
1020
9870
1.19
1.56
4.8
4.7
6.0
6.0
mmol/l
0.02
926
8954
8
33
2.43
1.54
1.0
9.6
—
64.3
—
0
14
9
37
2.44
1.48
1.2
1.4
—
—
—
0
0
5
16
3.13
1.44
1.4
2.1
—
—
—
0
0
29
188
1.56
1.43
1.1
1.2
—
—
—
0
0
47
337
1.41
1.43
1.7
1.3
29.7
32.4
iu/l
0.20
38
286
28
181
1.56
1.41
1.6
1.6
—
—
—
0
0
42
297
1.43
1.39
1.6
1.5
266.3
295.6
ug/g
0.38
26
176
20
120
1.68
1.34
1.4
1.2
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
44
317
1.40
1.32
2.9
2.8
0.3
0.4
u/ml
0.88
22
179
45
326
1.39
1.31
1.4
3.4
1.4
2.0
ratio
—
6
21
104
849
1.25
1.31
3.4
3.6
1.2
1.2
mmol/l
1.12
95
728
41
295
1.40
1.25
1.7
1.7
—
—
—
0
0
36
253
1.44
1.25
1.7
1.7
—
—
—
0
0
6
25
2.41
1.24
1.0
1.2
1.1
206.6
mg/l
—
6
17
354
3226
1.14
1.24
4.5
4.8
2.1
2.8
ug/l
1.06
314
2865
983
9533
1.15
1.23
18.3
13.2
81.1
79.6
ml/min/173m2
1.25
839
7878
36
254
1.43
1.23
1.2
1.2
—
—
—
0
0
1034
10068
1.17
1.21
4.6
4.5
4.7
4.7
mmol/l
0.39
944
9289
249
2221
1.15
1.20
1.7
1.7
51244238.1
34449140.0
pmol/l
0.12
201
1823
32
222
1.45
1.19
1.3
1.5
—
—
—
0
0
6
26
2.31
1.18
1.2
1.1
—
—
—
0
0
34
241
1.42
1.14
2.7
3.0
35.7
33.7
umol/l
0.21
29
198
31
216
1.45
1.14
2.8
2.5
16.0
16.2
%
0.07
18
108
7
30
2.34
1.12
1.1
1.1
—
—
—
0
0
41
303
1.37
1.10
1.3
1.1
—
—
—
0
0
26
177
1.48
1.08
1.2
1.2
320.2
280.9
u/ml
0.30
16
103
34
245
1.40
1.06
1.7
1.8
—
—
—
0
0
35
254
1.39
1.05
3.1
2.7
25.6
25.2
mmol/l
0.22
30
225
1024
9992
1.14
1.03
4.6
4.5
1.5
1.5
mmol/l
0.70
936
9150
11
60
1.84
1.03
1.4
1.2
—
—
—
0
0
111
942
1.20
1.00
2.9
2.3
689.8
40.5
u/l
0.49
92
796
19
123
1.55
1.00
1.6
1.2
102.2
25.0
u/ml
—
5
7
105
888
1.20
0.99
2.5
2.4
8.9
7.4
ug/l
0.17
88
782
40
301
1.34
0.98
1.3
1.1
—
—
—
0
0
74
605
1.24
0.97
1.9
1.6
—
—
—
0
0
46
356
1.30
0.94
1.5
1.7
—
—
—
0
0
6
27
2.23
0.93
1.2
1.3
—
—
—
0
0
9
52
1.74
0.92
4.7
3.8
—
—
—
0
0
10
171
0.58
0.92
1.3
1.5
—
—
—
0
0
5
101
0.49
0.89
1.4
1.5
—
—
—
0
0
23
160
1.45
0.89
1.4
1.4
106.5
104.1
u/ml
—
6
29
28
203
1.39
0.87
1.3
1.4
—
—
—
0
0
28
203
1.39
0.87
1.3
1.4
—
—
—
0
0
161
1428
1.15
0.87
1.4
1.4
—
—
—
0
0
19
274
0.69
0.85
1.5
1.4
—
—
—
0
0
14
88
1.60
0.84
1.3
1.9
1.4
2.6
u/field
—
9
39
1045
10245
1.13
0.83
5.3
5.0
2.7
2.8
mmol/l
1.18
953
9400
19
130
1.47
0.81
1.2
1.5
—
—
—
0
0
10
58
1.73
0.79
1.2
1.3
—
84.4
—
0
9
19
131
1.46
0.78
1.2
1.5
—
—
—
0
0
19
131
1.46
0.78
1.2
1.5
—
—
—
0
0
56
457
1.24
0.78
5.3
3.4
24.6
24.2
mmol/l
0.23
44
416
6
34
1.77
0.76
1.0
1.0
—
—
—
0
0
20
142
1.42
0.72
1.6
1.5
—
—
—
0
0
7
40
1.75
0.71
1.3
1.1
315.6
199.7
iu/ml
—
7
40
7
40
1.75
0.71
1.1
1.6
—
—
—
0
0
22
160
1.38
0.70
1.6
1.5
—
—
—
0
0
48
392
1.23
0.69
1.9
1.9
—
—
—
0
0
7
42
1.67
0.68
1.3
1.5
—
—
—
0
0
20
144
1.40
0.68
1.5
1.6
—
—
—
0
0
278
2586
1.10
0.68
4.0
4.1
22.4
21.6
%
0.37
136
1209
80
689
1.17
0.67
2.1
2.2
12.7
13.2
nmol/l
0.22
67
607
141
1269
1.13
0.64
4.2
4.6
31.6
32.5
%
0.43
98
844
29
370
0.78
0.64
1.6
1.8
8.8
4.5
mg/l
0.34
19
273
18
129
1.40
0.63
1.2
1.5
—
—
—
0
0
18
129
1.40
0.63
1.2
1.5
—
—
—
0
0
18
130
1.39
0.61
1.2
1.5
—
—
—
0
0
8
50
1.60
0.61
2.9
2.5
—
—
—
0
0
52
437
1.20
0.59
1.1
1.0
—
—
—
0
0
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
13
90
1.45
0.55
1.0
1.0
—
—
—
0
0
38
312
1.22
0.55
1.8
1.7
—
—
—
0
0
16
116
1.38
0.54
1.7
1.8
—
—
—
0
0
9
61
1.48
0.53
1.8
2.2
—
—
—
0
0
17
226
0.75
0.52
3.1
3.5
29.4
23.1
mg/l
—
9
139
6
40
1.50
0.51
1.0
1.0
—
—
—
0
0
27
215
1.26
0.51
1.6
1.3
7.3
10.6
u/l
1.35
21
171
15
109
1.38
0.51
2.1
2.6
—
—
—
0
0
27
217
1.25
0.48
3.4
3.2
7.0
7.7
mmol/l
0.71
27
212
12
85
1.42
0.47
1.6
1.4
—
—
—
0
0
31
255
1.22
0.46
1.2
1.6
—
—
—
0
0
19
148
1.29
0.43
1.6
1.3
0.7
0.6
nmol/l
0.40
19
141
19
148
1.29
0.43
1.7
2.3
501.6
88.0
u/ml
0.59
19
142
28
230
1.22
0.42
3.4
3.1
1.9
1.5
mmol/l
0.46
28
223
5
32
1.56
0.42
1.4
3.1
—
—
—
0
0
5
32
1.56
0.42
1.4
3.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
32.9
—
0
18
28
233
1.21
0.39
1.4
1.3
277.1
223.0
miu/ml
0.21
11
105
11
80
1.38
0.38
1.2
1.4
—
—
—
0
0
8
115
0.69
0.37
1.0
1.7
—
—
—
0
0
8
115
0.69
0.37
1.0
1.1
—
—
—
0
0
9
70
1.29
0.36
1.3
1.4
12.1
13.6
u/l
—
9
64
13
168
0.77
0.35
1.2
1.1
—
—
—
0
0
197
1867
1.07
0.34
3.0
2.9
0.7
0.8
ug/l
0.66
134
1193
36
312
1.16
0.33
1.3
1.4
—
—
—
0
0
22
183
1.21
0.32
1.5
1.9
—
—
—
0
0
64
581
1.11
0.31
2.5
3.2
4.4
4.5
pmol/l
0.37
59
510
7
55
1.27
0.30
1.1
1.9
—
—
—
0
0
7
55
1.27
0.30
1.1
1.9
—
—
—
0
0
7
55
1.27
0.30
1.1
1.9
—
—
—
0
0
7
55
1.27
0.30
1.1
1.9
—
—
—
0
0
28
241
1.17
0.29
1.5
1.7
4.6
5.2
iu/l
—
9
79
8
109
0.73
0.29
1.0
1.1
—
—
—
0
0
27
233
1.16
0.27
1.4
1.8
—
—
—
0
0
5
72
0.69
0.26
1.0
1.1
—
—
—
0
0
9
74
1.22
0.25
1.6
1.5
—
—
—
0
0
973
9643
1.04
0.23
4.1
4.0
1.3
1.3
mmol/l
0.02
878
8776
16
134
1.20
0.23
1.1
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
2.9
—
74.4
—
0
11
0
12
0.00
0.21
0.0
5.8
—
—
—
0
0
5
43
1.16
0.21
1.2
2.2
—
—
—
0
0
5
43
1.16
0.21
1.2
2.2
—
—
—
0
0
5
43
1.16
0.21
1.2
2.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
16
136
1.18
0.20
1.6
2.0
194.2
3430.4
u/l
—
6
52
9
113
0.79
0.20
1.2
1.1
95.1
96.4
%
—
9
106
6
52
1.15
0.19
1.2
3.3
511.3
1540.4
u/ml
—
6
52
28
252
1.11
0.18
1.8
1.7
35.1
39.6
nmol/l
0.81
28
241
7
60
1.17
0.17
1.0
1.1
—
—
—
0
0
13
110
1.18
0.17
4.5
3.4
—
—
—
0
0
5
66
0.76
0.17
1.0
1.3
—
—
—
0
0
11
93
1.18
0.14
1.3
1.7
—
—
—
0
0
11
93
1.18
0.14
1.3
1.7
—
—
—
0
0
11
93
1.18
0.14
1.3
1.7
—
—
—
0
0
66
626
1.06
0.14
1.3
1.2
219.6
190.5
u/ml
0.21
59
573
27
247
1.10
0.13
1.2
1.1
—
—
—
0
0
32
296
1.08
0.13
1.4
1.9
—
—
—
0
0
150
1456
1.03
0.13
1.7
1.4
—
—
—
0
0
27
248
1.09
0.12
1.6
1.3
—
—
—
0
0
16
142
1.13
0.12
1.2
1.1
—
—
—
0
0
16
142
1.13
0.12
1.2
1.1
—
—
—
0
0
51
482
1.06
0.12
1.3
1.3
—
—
—
0
0
17
152
1.12
0.12
1.6
1.6
—
—
—
0
0
118
1142
1.04
0.12
1.6
1.8
1.6
1.5
%
0.45
92
998
16
144
1.11
0.10
1.1
1.1
1.5
1.5
g/l
0.01
16
129
17
155
1.10
0.09
1.2
1.2
2.1
6.9
u/ml
—
9
66
18
165
1.09
0.08
1.2
1.1
1.0
117.7
iu/ml
—
5
33
87
845
1.03
0.08
1.8
1.8
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
64
1.09
0.08
1.0
1.2
—
—
—
0
0
7
67
1.05
0.08
1.0
1.0
898.9
297.2
ng/l
—
7
44
7
67
1.05
0.08
1.0
1.0
23.7
44.1
ng/l
—
7
42
7
67
1.05
0.08
1.0
1.0
1031.0
644.2
ng/l
—
7
43
67
648
1.04
0.08
1.2
1.2
68.2
145.5
iu/ml
1.56
20
263
8
74
1.08
0.07
1.3
1.6
1.1
1.0
g/l
—
8
74
9
84
1.07
0.07
1.4
1.7
—
—
—
0
0
22
234
0.94
0.06
1.3
1.2
3.8
3.8
mmol/l
0.01
22
222
9
100
0.90
0.06
1.0
1.1
—
—
—
0
0
27
257
1.05
0.05
2.0
2.4
119.7
95.7
ug/min
0.15
17
155
16
149
1.07
0.05
1.2
1.1
—
10.2
—
0
8
11
102
1.08
0.03
1.3
1.1
—
—
—
0
0
15
142
1.06
0.02
1.1
1.1
—
—
—
0
0
10
107
0.93
0.02
1.8
1.8
—
—
—
0
0
22
226
0.97
0.00
3.2
3.2
1.2
0.9
nmol/l
0.65
17
175
15
146
1.03
0.00
1.1
1.1
0.2
1.9
u/ml
—
9
58
18
184
0.98
0.00
1.8
1.9
190.7
215.9
pmol/l
0.80
18
171
23
234
0.98
0.00
1.3
1.4
2.2
25.4
e6/l
0.96
18
177
12
117
1.03
0.00
1.7
1.8
—
—
—
0
0
15
153
0.98
0.00
1.2
1.2
2.1
3.9
u/ml
—
7
43
10
105
0.95
0.00
1.2
1.6
—
—
—
0
0
7
72
0.97
0.00
1.0
1.1
—
—
—
0
0
7
72
0.97
0.00
1.0
1.1
—
—
—
0
0
6
61
0.98
0.00
1.8
1.6
—
—
—
0
0
7
69
1.01
0.00
1.4
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
0.00
1.6
1.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
5
55
0.91
0.00
1.4
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
7
70
1.00
0.00
1.6
1.2
—
—
—
0
0
5
55
0.91
0.00
1.6
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
0.00
1.8
1.6
—
—
—
0
0
5
59
0.85
0.00
1.0
1.1
—
—
—
0
0
7
71
0.99
0.00
1.0
1.1
—
—
—
0
0
7
72
0.97
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
7
71
0.99
0.00
1.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint SCND_OTH_COXARTHROSIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| SCND_OTH_COXARTHROSIS | 1.241 [1.1, 1.4] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.091 |
During the follow-up period (1.1.1998 — 31.12.2019), 576 out of 2900 females with SCND_OTH_COXARTHROSIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| SCND_OTH_COXARTHROSIS | 1.309 [1.14, 1.5] | < 0.001 |
| Birth year | 0.982 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 511 out of 2439 males with SCND_OTH_COXARTHROSIS died.
Mortality risk
Mortality risk for people of age
years, who have SCND_OTH_COXARTHROSIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.113% | 0.202% |
| 5 | 0.711% | 1.345% |
| 10 | 1.79% | 3.359% |
| 15 | 3.356% | 6.236% |
| 20 | 5.844% | 10.313% |
Relationships between endpoints
↥Index endpoint: SCND_OTH_COXARTHROSIS – Other secondary coxarthrosis
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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