This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Abnormal findings in cerebrospinal fluid
R18_ABNORMAL_FINDI_CEREBROS_FLUID
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
115 |
4. Check minimum number of eventsNone |
115 |
5. Include endpointsNone |
115 |
6. Filter based on genotype QC (FinnGen only) |
110 |
Control definitions (FinnGen only)
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- R8[3-9]
- Name in latin
- Reperta abnormia in liquore cerebrospinali
Similar endpoints
↥List of similar endpoints to
Abnormal findings in cerebrospinal fluid
based on the number of shared cases.
Similar with more cases:
- Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 110 | 72 | 38 |
| Unadjusted period prevalence (%) | 0.02 | 0.03 | 0.02 |
| Median age at first event (years) | 50.04 | 49.57 | 50.94 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 115
- Matched controls
- 1150
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
TAB00
NOMESCO Finland
Lumbar puncture
10.9
26.2
33
41
R83.8
ICD-10 Finland
Abnormal findings in cerebrospinal fluid, Other abnormal findings
+∞
24.9
23
*
R83.4
ICD-10 Finland
Abnormal findings in cerebrospinal fluid, Abnormal immunological findings
+∞
24.9
23
*
R83.6
ICD-10 Finland
Abnormal findings in cerebrospinal fluid, Abnormal cytological findings
+∞
22.6
21
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
7.1
17.3
31
57
R83.9
ICD-10 Finland
Abnormal findings in cerebrospinal fluid, Unspecified abnormal finding
+∞
12.7
12
*
R83.0
ICD-10 Finland
Abnormal findings in cerebrospinal fluid, Abnormal level of enzymes
+∞
12.7
12
*
R83.2
ICD-10 Finland
Abnormal findings in cerebrospinal fluid, Abnormal level of other drugs, medicaments and biological substances
+∞
11.7
11
*
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
60.2
9.8
11
*
Z01.8
ICD-10 Finland
Other specified special examinations
3.7
9.6
40
144
R51.80
ICD-10 Finland
Headache
3.5
8.5
38
142
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.4
8.4
24
65
H02AB06
ATC
prednisolone; systemic
3.1
8.1
73
409
TPH04
NOMESCO Finland
Cathetrisation of vein
3.4
7.9
36
135
N02AX02
ATC
tramadol; systemic, rectal
3.0
7.9
64
337
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
10.4
7.5
14
15
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.8
7.1
62
335
N06AA09
ATC
amitriptyline; systemic
4.4
7.0
19
49
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
18.1
6.9
10
6
G35
ICD-10 Finland
Multiple sclerosis
15.5
6.5
10
7
J01MA02
ATC
ciprofloxacin; systemic
2.7
6.4
54
283
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.7
6.4
56
299
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.6
6.4
24
79
R83.5
ICD-10 Finland
Abnormal findings in cerebrospinal fluid, Abnormal microbiological findings
+∞
6.3
6
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
6.7
6.2
15
25
R42
ICD-10 Finland
Dizziness and giddiness
3.0
6.2
34
141
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
28
28
12.90
25.78
1.8
1.3
200.35
3.00
e6/l
0.54
23
23
25
61
4.96
10.04
7.1
3.8
1.22
1.23
mmol/l
0.31
25
54
76
415
3.45
9.23
7.4
6.1
1.21
1.22
mmol/l
0.77
63
358
89
549
3.75
8.61
10.6
10.2
4.40
3.97
e9/l
1.12
79
485
16
18
10.12
8.36
1.2
1.2
—
—
—
0
0
16
18
10.12
8.36
1.2
1.2
—
—
—
0
0
77
440
3.27
8.36
4.2
3.3
0.00
0.01
estimate
0.49
31
94
77
441
3.26
8.31
5.3
4.5
0.00
0.00
estimate
-0.00
29
89
13
10
14.46
8.10
1.2
1.0
—
—
—
0
0
14
13
12.07
8.05
1.9
1.5
—
—
—
0
0
77
447
3.19
8.00
4.2
3.3
0.00
0.00
estimate
-0.00
27
89
65
346
3.02
7.84
4.6
3.4
—
—
—
0
0
56
277
2.99
7.68
2.3
2.1
119.06
151.51
u/l
0.46
49
262
14
15
10.45
7.53
1.1
1.1
—
—
—
0
0
10
6
18.06
6.88
1.2
1.5
—
—
—
0
0
50
252
2.74
6.37
3.5
2.5
0.56
0.26
e6/l
0.40
40
186
65
381
2.62
6.03
15.7
11.0
1.22
1.19
inr
0.11
33
117
16
41
4.37
5.94
2.5
2.0
36.31
47.00
u/l
1.14
16
36
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
10
9
12.02
5.92
1.1
1.4
—
—
—
0
0
32
132
2.97
5.87
3.8
1.8
11.56
13.96
umol/l
1.08
26
117
23
78
3.44
5.81
3.5
3.0
—
—
—
0
0
56
312
2.55
5.69
3.8
2.7
—
—
—
0
0
79
526
2.60
5.38
6.6
4.1
6.96
6.61
mmol/l
0.48
73
486
69
434
2.47
5.27
3.7
2.5
118.08
100.84
ug/l
0.29
63
398
10
13
8.30
4.96
1.3
1.1
—
—
—
0
0
45
239
2.45
4.92
5.3
3.7
0.00
0.00
estimate
-0.00
29
86
12
21
6.25
4.90
2.9
1.2
—
—
—
0
0
11
17
7.03
4.90
1.7
1.2
—
—
—
0
0
40
203
2.49
4.81
3.0
1.9
3.92
2.84
mg/l
0.93
35
173
55
330
2.28
4.47
4.4
2.9
46.52
39.93
ng/l
0.09
40
200
9
13
7.40
4.25
3.4
3.9
61.78
58.62
%
—
9
13
106
892
3.40
3.99
21.7
11.3
87.71
85.82
ml/min/173m2
0.41
96
729
53
325
2.17
3.97
1.9
1.9
98.38
97.70
pmol/l
0.04
25
180
14
39
3.94
3.86
6.1
7.1
25.41
24.95
mmol/l
0.17
14
39
6
5
12.55
3.80
1.2
1.0
—
—
—
0
0
6
5
12.55
3.80
1.3
1.8
—
—
—
0
0
51
319
2.08
3.54
5.1
2.8
41.67
31.19
u/l
0.30
46
300
14
49
3.11
3.32
1.6
1.3
—
—
—
0
0
9
19
5.04
3.31
4.9
1.6
24.99
26.34
mmol/l
—
9
19
21
95
2.48
3.13
4.5
7.2
105.86
104.23
mmol/l
1.02
21
95
5
5
10.37
3.00
1.0
1.4
—
—
—
0
0
5
5
10.37
3.00
1.2
1.6
—
—
—
0
0
26
133
2.23
2.95
1.6
1.7
—
—
—
0
0
9
22
4.34
2.95
1.2
1.2
—
—
—
0
0
90
721
2.14
2.89
5.1
3.9
14.55
14.58
pmol/l
0.03
85
661
5
6
8.64
2.77
1.0
1.2
—
—
—
0
0
5
6
8.64
2.77
1.4
1.8
—
—
—
0
0
109
973
3.30
2.71
23.9
11.8
16.88
21.21
mg/l
0.84
91
753
30
168
2.06
2.71
3.6
3.0
28.93
71.80
ng/l
0.62
24
118
48
318
1.87
2.67
3.3
2.7
2.32
2.37
mmol/l
1.18
40
280
34
201
1.98
2.64
1.9
1.8
0.70
0.85
mg/l
0.21
28
159
6
11
5.68
2.57
1.3
1.0
—
—
—
0
0
7
17
4.31
2.40
1.1
1.5
—
—
—
0
0
10
36
2.94
2.20
1.7
1.7
—
—
—
0
0
30
182
1.88
2.13
1.6
1.8
463.72
455.73
pmol/l
0.04
25
159
35
224
1.81
2.10
1.4
1.3
0.79
1.90
u/ml
0.64
12
61
5
10
5.17
2.09
2.8
2.7
104.80
107.20
mmol/l
—
5
10
10
38
2.78
2.06
1.2
1.5
—
—
—
0
0
5
11
4.70
1.96
2.0
2.0
—
—
—
0
0
32
204
1.79
1.93
1.2
1.3
39.13
29.86
iu/ml
0.16
12
68
7
22
3.32
1.91
5.9
1.6
141.00
130.23
g/l
—
7
13
9
35
2.70
1.84
2.2
10.0
22.22
24.44
mmol/l
—
9
35
99
868
2.01
1.83
28.8
14.0
14.23
14.58
%
0.38
99
858
16
82
2.10
1.80
2.8
2.5
0.21
0.22
g/l
0.11
16
74
31
200
1.75
1.79
1.3
1.3
3.33
9.74
u/ml
0.89
17
82
33
220
1.70
1.69
2.4
2.7
855.61
630.11
ng/l
0.29
28
187
16
85
2.02
1.65
1.5
1.6
—
—
—
0
0
5
14
3.68
1.63
1.0
1.3
—
—
—
0
0
7
26
2.80
1.61
1.3
1.2
—
—
—
0
0
5
16
3.22
1.45
1.0
1.1
—
—
—
0
0
30
203
1.65
1.45
2.5
1.5
—
—
—
0
0
16
90
1.90
1.41
1.6
1.6
—
—
—
0
0
9
44
2.13
1.30
1.2
1.4
—
—
—
0
0
11
57
2.03
1.21
1.9
1.5
—
—
—
0
0
25
169
1.61
1.20
1.2
1.2
—
—
—
0
0
21
136
1.67
1.19
2.4
2.3
1.41
2.93
e6/l
0.67
11
67
0
33
0.00
1.18
0.0
1.4
—
258.31
—
0
18
8
41
2.02
1.11
1.6
1.7
—
—
—
0
0
9
46
2.04
1.06
6.7
9.5
0.64
0.69
%
—
9
46
9
46
2.04
1.06
6.7
9.6
1.33
1.57
%
—
9
46
22
149
1.59
1.05
2.3
2.2
0.69
0.75
e6/l
0.07
12
81
5
22
2.33
1.04
1.4
2.3
—
—
—
0
0
95
864
1.57
1.02
5.3
5.1
40.50
39.06
mmol/mol
0.65
90
815
5
103
0.46
0.95
2.2
4.7
28.20
32.39
%
—
5
69
55
458
1.39
0.93
2.7
2.4
—
—
—
0
0
6
29
2.13
0.91
1.3
1.2
—
46.50
—
0
5
6
30
2.05
0.88
2.2
3.0
—
—
—
0
0
6
31
1.99
0.85
1.0
1.2
—
—
—
0
0
6
31
1.99
0.85
1.0
1.2
—
—
—
0
0
14
90
1.63
0.82
2.4
2.4
44.43
29.59
u/l
0.64
14
78
5
96
0.50
0.82
2.6
6.8
—
—
—
0
0
6
33
1.86
0.80
1.2
1.2
—
—
—
0
0
6
34
1.81
0.77
1.3
1.3
—
2.33
—
0
8
9
58
1.60
0.72
1.0
1.3
—
—
—
0
0
5
26
1.96
0.71
1.0
1.2
—
—
—
0
0
17
121
1.48
0.67
2.0
1.6
1.59
1.46
%
0.19
11
105
0
22
0.00
0.60
0.0
2.0
—
—
—
0
0
6
36
1.70
0.57
2.5
2.6
0.82
1.38
%
—
6
36
96
912
1.32
0.46
4.3
4.2
6.18
5.84
mmol/l
0.49
91
855
8
56
1.46
0.43
1.0
1.0
—
—
—
0
0
5
32
1.59
0.43
1.4
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
11
80
1.41
0.40
2.6
1.7
—
—
—
0
0
5
36
1.41
0.38
2.0
1.9
—
—
—
0
0
29
249
1.22
0.35
1.4
1.7
1.59
1.36
mmol/l
0.59
24
213
94
909
1.19
0.24
3.9
3.8
1.30
1.25
mmol/l
0.26
89
846
7
90
0.76
0.23
1.4
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
6
48
1.26
0.20
3.3
2.3
232.83
93.49
ng/l
—
6
41
17
196
0.84
0.20
4.4
3.5
23.36
22.64
%
—
7
74
98
959
1.15
0.15
5.0
4.6
2.77
2.83
mmol/l
0.27
93
895
27
249
1.11
0.13
3.4
3.8
16.79
15.30
mg/mmol
0.04
17
150
15
134
1.14
0.11
4.5
1.6
—
—
—
0
0
23
216
1.08
0.07
2.3
2.2
—
—
—
0
0
13
142
0.90
0.07
3.8
2.4
1.15
0.73
ug/l
—
8
86
12
109
1.11
0.06
1.6
1.5
—
—
—
0
0
69
677
1.05
0.05
4.6
3.3
—
—
—
0
0
16
151
1.07
0.03
5.3
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
64.00
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.3
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: R18_ABNORMAL_FINDI_CEREBROS_FLUID – Abnormal findings in cerebrospinal fluid
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).